CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP021105	Staphylococcus aureus strain CC5 chromosome, complete genome	11 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	5	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP021105_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_1

153975-154059

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_1

>merge|CP021105|1|153975-154059|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>CP021105|1|1|153975-154059|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU05739.1\|149589_149916_-\|monooxygenase-IsdI	unknown	unknown	gnl\|CDD\|183968
CP021105.1\|AVU05743.1\|154120_154324_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU08184.1\|162741_169917_+\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
CP021105.1\|AVU05742.1\|152866_153826_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
CP021105.1\|AVU08183.1\|159633_160659_+\|formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
CP021105.1\|AVU05740.1\|149922_150306_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377291
CP021105.1\|AVU05736.1\|146099_146987_+\|UDP-glucose-4-epimerase	unknown	unknown	gnl\|CDD\|187543
CP021105.1\|AVU05735.1\|145542_146100_+\|lipid-carrier--UDP-N-acetylgalactosaminyltransferase	unknown	unknown	gnl\|CDD\|225059
CP021105.1\|AVU05749.1\|159100_159460_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227896
CP021105.1\|AVU05744.1\|154502_155015_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379428
CP021105.1\|AVU05750.1\|161044_162295_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
CP021105.1\|AVU05738.1\|148379_149525_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458
CP021105.1\|AVU05746.1\|156110_157082_+\|nitrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
CP021105.1\|AVU05734.1\|144326_145532_+\|glycosyltransferase-WbuB	unknown	unknown	gnl\|CDD\|340825
CP021105.1\|AVU05737.1\|147040_148303_+\|UDP-N-acetyl-D-mannosamine-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
CP021105.1\|AVU05741.1\|150732_152220_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143435
CP021105.1\|AVU05733.1\|143120_144326_+\|capsular-biosynthesis-protein	unknown	unknown	unknown
CP021105.1\|AVU05748.1\|157852_158884_+\|butyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
CP021105.1\|AVU05747.1\|157078_157840_+\|sulfonate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
CP021105.1\|AVU05745.1\|155356_156097_+\|sulfonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU05739.1\|149589_149916_-\|monooxygenase-IsdI	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
CP021105.1\|AVU05746.1\|156110_157082_+\|nitrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.75927e-52
CP021105.1\|AVU08184.1\|162741_169917_+\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
CP021105.1\|AVU05742.1\|152866_153826_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.11026e-108
CP021105.1\|AVU08183.1\|159633_160659_+\|formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
CP021105.1\|AVU05740.1\|149922_150306_-\|hypothetical-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	5.80598e-41
CP021105.1\|AVU05736.1\|146099_146987_+\|UDP-glucose-4-epimerase	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.93098e-117
CP021105.1\|AVU05735.1\|145542_146100_+\|lipid-carrier--UDP-N-acetylgalactosaminyltransferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.08096e-87
CP021105.1\|AVU05749.1\|159100_159460_+\|hypothetical-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
CP021105.1\|AVU05744.1\|154502_155015_+\|hypothetical-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
CP021105.1\|AVU05738.1\|148379_149525_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
CP021105.1\|AVU05750.1\|161044_162295_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
CP021105.1\|AVU05734.1\|144326_145532_+\|glycosyltransferase-WbuB	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	3.56278e-74
CP021105.1\|AVU05737.1\|147040_148303_+\|UDP-N-acetyl-D-mannosamine-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
CP021105.1\|AVU05741.1\|150732_152220_+\|aldehyde-dehydrogenase	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
CP021105.1\|AVU05748.1\|157852_158884_+\|butyryl-CoA-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67474e-20
CP021105.1\|AVU05747.1\|157078_157840_+\|sulfonate-ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
CP021105.1\|AVU05745.1\|155356_156097_+\|sulfonate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.18703e-112

>CP021105.1|AVU05742.1|152866_153826_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILVAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>CP021105.1|AVU05741.1|150732_152220_+|aldehyde-dehydrogenase
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>CP021105.1|AVU05740.1|149922_150306_-|hypothetical-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>CP021105.1|AVU05739.1|149589_149916_-|monooxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>CP021105.1|AVU05738.1|148379_149525_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLADLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK
>CP021105.1|AVU05737.1|147040_148303_+|UDP-N-acetyl-D-mannosamine-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEVYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLEKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDICLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>CP021105.1|AVU05736.1|146099_146987_+|UDP-glucose-4-epimerase
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLTYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>CP021105.1|AVU05735.1|145542_146100_+|lipid-carrier--UDP-N-acetylgalactosaminyltransferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>CP021105.1|AVU05734.1|144326_145532_+|glycosyltransferase-WbuB
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKPLVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>CP021105.1|AVU05733.1|143120_144326_+|capsular-biosynthesis-protein
MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSILTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFLYFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYYLIQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLYLDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKTNLFAIAALCLVMIICYPITLIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLNTKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKSKFINKKDVD
>CP021105.1|AVU05743.1|154120_154324_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>CP021105.1|AVU05744.1|154502_155015_+|hypothetical-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>CP021105.1|AVU05745.1|155356_156097_+|sulfonate-ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNVIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEDRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIMETFALNHHQVEPEYYL
>CP021105.1|AVU05746.1|156110_157082_+|nitrate-ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>CP021105.1|AVU05747.1|157078_157840_+|sulfonate-ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>CP021105.1|AVU05748.1|157852_158884_+|butyryl-CoA-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>CP021105.1|AVU05749.1|159100_159460_+|hypothetical-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>CP021105.1|AVU08183.1|159633_160659_+|formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKAIGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSSSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>CP021105.1|AVU05750.1|161044_162295_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>CP021105.1|AVU08184.1|162741_169917_+|non-ribosomal-peptide-synthetase
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKDATPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHRNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELLEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPEAIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSGLNVAQLQQAVQHLIARHEILRTQYIVVDDEVRQRIVADVVADFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQQLINKHRVTVASIPLQMCSIMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENVILAIRGISDCVVTVSHFDTHDILNAYYVGEQQVEQDLKQYLNDQLPKYMIPKTITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMYQNQQSLVALPDNLSELQKIVMSRYNLGILEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: CP021105_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_2

393768-393869

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_2

>merge|CP021105|2|393768-393869|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>CP021105|2|2|393768-393869|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU05960.1\|393885_394842_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
CP021105.1\|AVU05964.1\|397262_398531_+\|xanthine-permease	unknown	unknown	gnl\|CDD\|274468
CP021105.1\|AVU05966.1\|400059_401601_+\|GMP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|234614
CP021105.1\|AVU05954.1\|388099_388669_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP021105.1\|AVU05965.1\|398568_400035_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP021105.1\|AVU05957.1\|391468_391567_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU05958.1\|391777_392035_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU05956.1\|389995_391384_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
CP021105.1\|AVU05951.1\|384837_385221_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU05950.1\|384190_384772_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP021105.1\|AVU05968.1\|402641_403346_-\|growth-inhibitor-PemK	unknown	unknown	gnl\|CDD\|367091
CP021105.1\|AVU05955.1\|389160_389916_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP021105.1\|AVU05959.1\|392235_393555_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
CP021105.1\|AVU05952.1\|385490_386117_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380196
CP021105.1\|AVU05962.1\|395764_396172_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP021105.1\|AVU05953.1\|386560_388084_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP021105.1\|AVU05967.1\|401713_402250_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU05961.1\|394959_395622_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU05969.1\|403744_404017_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
CP021105.1\|AVU05963.1\|396684_397263_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU05960.1\|393885_394842_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416
CP021105.1\|AVU05964.1\|397262_398531_+\|xanthine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	5.74823e-170
CP021105.1\|AVU05966.1\|400059_401601_+\|GMP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP021105.1\|AVU05954.1\|388099_388669_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
CP021105.1\|AVU05965.1\|398568_400035_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP021105.1\|AVU05962.1\|395764_396172_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
CP021105.1\|AVU05956.1\|389995_391384_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP021105.1\|AVU05969.1\|403744_404017_-\|hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
CP021105.1\|AVU05950.1\|384190_384772_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
CP021105.1\|AVU05968.1\|402641_403346_-\|growth-inhibitor-PemK	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.38181e-08
CP021105.1\|AVU05955.1\|389160_389916_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	4.50551e-88
CP021105.1\|AVU05959.1\|392235_393555_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.75686e-114
CP021105.1\|AVU05952.1\|385490_386117_-\|hypothetical-protein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
CP021105.1\|AVU05953.1\|386560_388084_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP021105.1\|AVU05963.1\|396684_397263_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119

>CP021105.1|AVU05959.1|392235_393555_+|ISL3-family-transposase
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPNYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRRSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKVVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA
>CP021105.1|AVU05958.1|391777_392035_-|hypothetical-protein
MLVNDESHKGTLIFTFTTNAFFLKQKYLFTVAFELPPAHTNPQKMLILIRQNFLQRVCSKRLFKVDHLLSFYSINMRLAIFIKPS
>CP021105.1|AVU05957.1|391468_391567_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG
>CP021105.1|AVU05956.1|389995_391384_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>CP021105.1|AVU05955.1|389160_389916_+|NADPH-dependent-oxidoreductase
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP021105.1|AVU05954.1|388099_388669_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP021105.1|AVU05953.1|386560_388084_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP021105.1|AVU05952.1|385490_386117_-|hypothetical-protein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP021105.1|AVU05951.1|384837_385221_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>CP021105.1|AVU05950.1|384190_384772_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>CP021105.1|AVU05960.1|393885_394842_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP021105.1|AVU05961.1|394959_395622_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP021105.1|AVU05962.1|395764_396172_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>CP021105.1|AVU05963.1|396684_397263_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP021105.1|AVU05964.1|397262_398531_+|xanthine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP021105.1|AVU05965.1|398568_400035_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDAIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP021105.1|AVU05966.1|400059_401601_+|GMP-synthase-(glutamine-hydrolyzing)
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP021105.1|AVU05967.1|401713_402250_-|hypothetical-protein
MHNKNEFNKKLKDFIGSDKRMALVKGYINEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNKIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>CP021105.1|AVU05968.1|402641_403346_-|growth-inhibitor-PemK
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSFSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALTQKYRDIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>CP021105.1|AVU05969.1|403744_404017_-|hypothetical-protein
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Crispr_ID: CP021105_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_3

742721-742803

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_3

>merge|CP021105|3|742721-742803|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>CP021105|3|3|742721-742803|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU06271.1\|729628_730339_+\|allophanate-hydrolase	unknown	unknown	gnl\|CDD\|224960
CP021105.1\|AVU06281.1\|743014_743182_+\|nitrogen-fixation-protein-NifR	unknown	unknown	unknown
CP021105.1\|AVU06283.1\|744458_744560_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06275.1\|735905_737687_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
CP021105.1\|AVU06279.1\|742029_742572_+\|5'(3')-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
CP021105.1\|AVU06288.1\|748254_748521_+\|ribonucleoside-diphosphate-reductase	unknown	unknown	unknown
CP021105.1\|AVU06273.1\|731800_733741_+\|lipoteichoic-acid-synthase	unknown	unknown	gnl\|CDD\|224287
CP021105.1\|AVU06272.1\|730322_731327_+\|allophanate-hydrolase	unknown	unknown	gnl\|CDD\|224895
CP021105.1\|AVU06274.1\|734010_735894_+\|heme-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223562
CP021105.1\|AVU06278.1\|740632_741691_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
CP021105.1\|AVU06270.1\|729334_729541_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06290.1\|749031_751137_+\|ribonucleotide-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
CP021105.1\|AVU06285.1\|746208_746454_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06284.1\|744637_746143_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225646
CP021105.1\|AVU06277.1\|738878_740393_+\|glycine/betaine-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|270328
CP021105.1\|AVU06282.1\|743450_744368_-\|lipid-kinase	unknown	unknown	gnl\|CDD\|224513
CP021105.1\|AVU06287.1\|747003_747870_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|223769
CP021105.1\|AVU06289.1\|748670_749069_+\|protein-NrdI	unknown	unknown	gnl\|CDD\|224694
CP021105.1\|AVU06276.1\|737908_738886_+\|glycine/betaine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
CP021105.1\|AVU06286.1\|746483_746984_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU06271.1\|729628_730339_+\|allophanate-hydrolase	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.34598e-94
CP021105.1\|AVU06275.1\|735905_737687_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
CP021105.1\|AVU06279.1\|742029_742572_+\|5'(3')-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
CP021105.1\|AVU06273.1\|731800_733741_+\|lipoteichoic-acid-synthase	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
CP021105.1\|AVU06272.1\|730322_731327_+\|allophanate-hydrolase	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
CP021105.1\|AVU06274.1\|734010_735894_+\|heme-ABC-transporter-ATP-binding-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
CP021105.1\|AVU06278.1\|740632_741691_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
CP021105.1\|AVU06290.1\|749031_751137_+\|ribonucleotide-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
CP021105.1\|AVU06284.1\|744637_746143_-\|MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
CP021105.1\|AVU06277.1\|738878_740393_+\|glycine/betaine-ABC-transporter-permease	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
CP021105.1\|AVU06282.1\|743450_744368_-\|lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79
CP021105.1\|AVU06287.1\|747003_747870_-\|EamA-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.04233e-10
CP021105.1\|AVU06289.1\|748670_749069_+\|protein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
CP021105.1\|AVU06276.1\|737908_738886_+\|glycine/betaine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	1.28246e-155
CP021105.1\|AVU06286.1\|746483_746984_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79

>CP021105.1|AVU06279.1|742029_742572_+|5'(3')-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>CP021105.1|AVU06278.1|740632_741691_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>CP021105.1|AVU06277.1|738878_740393_+|glycine/betaine-ABC-transporter-permease
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>CP021105.1|AVU06276.1|737908_738886_+|glycine/betaine-ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLDMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>CP021105.1|AVU06275.1|735905_737687_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>CP021105.1|AVU06274.1|734010_735894_+|heme-ABC-transporter-ATP-binding-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMIDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEVAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSYTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>CP021105.1|AVU06273.1|731800_733741_+|lipoteichoic-acid-synthase
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>CP021105.1|AVU06272.1|730322_731327_+|allophanate-hydrolase
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>CP021105.1|AVU06271.1|729628_730339_+|allophanate-hydrolase
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDIESLLKHYKIKLETFIELHSKTQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>CP021105.1|AVU06270.1|729334_729541_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIVTITTVISFILVYALIHELMPFVVRAMDLMYHQ
>CP021105.1|AVU06281.1|743014_743182_+|nitrogen-fixation-protein-NifR
MQVGVGRRNKFCENIISVPLPPIFKYTLALTNDKESLHNQSLVVLYHFRPALNKC
>CP021105.1|AVU06282.1|743450_744368_-|lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>CP021105.1|AVU06283.1|744458_744560_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS
>CP021105.1|AVU06284.1|744637_746143_-|MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>CP021105.1|AVU06285.1|746208_746454_-|hypothetical-protein
MIFLTYWCVFHLAYIIGYIKITFYTKVHQKNISTRIKQHFYRNLLHFNVNKYIFILSLINCARLITEYSQYFYFFVICWNI
>CP021105.1|AVU06286.1|746483_746984_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>CP021105.1|AVU06287.1|747003_747870_-|EamA-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>CP021105.1|AVU06288.1|748254_748521_+|ribonucleoside-diphosphate-reductase
MCLMYNETHNIVLVKRKRHNILCFVCKCFIYEEITFKSNLTQKFNSYYQLIVIFLENVLSKWKISNDVNTTYSDFYTFNPYKLLFSQI
>CP021105.1|AVU06289.1|748670_749069_+|protein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>CP021105.1|AVU06290.1|749031_751137_+|ribonucleotide-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI

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Crispr_ID: CP021105_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_4

783668-783746

Unclear

Consensus_repeat	Method
TGTAGAATTTCTTTTCGAAATTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_4

>merge|CP021105|4|783668-783746|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCT

>CP021105|4|4|783668-783746|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCT	CTGTGTTGGGGCCCCGCCAACTTGCATTGCC
TGTAGAATTTCTTTTCGAAATTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU06320.1\|780494_783341_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP021105.1\|AVU06324.1\|786282_787722_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276808
CP021105.1\|AVU06318.1\|777996_778233_+\|protein-CsbA	unknown	unknown	gnl\|CDD\|227234
CP021105.1\|AVU06312.1\|771971_774503_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
CP021105.1\|AVU06317.1\|777349_778000_+\|hydrolase	unknown	unknown	gnl\|CDD\|378993
CP021105.1\|AVU06311.1\|770985_771558_+\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP021105.1\|AVU06313.1\|774544_774649_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06314.1\|774932_775928_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP021105.1\|AVU06330.1\|793131_793719_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP021105.1\|AVU06322.1\|784942_785782_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP021105.1\|AVU06321.1\|784004_784937_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP021105.1\|AVU06326.1\|789051_789213_-\|nitrogen-fixation-protein-NifR	unknown	unknown	unknown
CP021105.1\|AVU06325.1\|787788_788724_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP021105.1\|AVU06323.1\|785789_786275_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP021105.1\|AVU06327.1\|789609_790521_+\|RNase-adaptor-protein-RapZ	unknown	unknown	gnl\|CDD\|224574
CP021105.1\|AVU06316.1\|776336_777176_+\|peptidase-M23	unknown	unknown	gnl\|CDD\|226451
CP021105.1\|AVU06328.1\|790517_791513_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
CP021105.1\|AVU06319.1\|778501_780487_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP021105.1\|AVU06329.1\|791623_792568_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
CP021105.1\|AVU06315.1\|776081_776189_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU06320.1\|780494_783341_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP021105.1\|AVU06318.1\|777996_778233_+\|protein-CsbA	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP021105.1\|AVU06312.1\|771971_774503_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP021105.1\|AVU06317.1\|777349_778000_+\|hydrolase	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP021105.1\|AVU06311.1\|770985_771558_+\|ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP021105.1\|AVU06324.1\|786282_787722_+\|hypothetical-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP021105.1\|AVU06314.1\|774932_775928_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP021105.1\|AVU06330.1\|793131_793719_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP021105.1\|AVU06322.1\|784942_785782_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
CP021105.1\|AVU06321.1\|784004_784937_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP021105.1\|AVU06325.1\|787788_788724_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP021105.1\|AVU06323.1\|785789_786275_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
CP021105.1\|AVU06327.1\|789609_790521_+\|RNase-adaptor-protein-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP021105.1\|AVU06328.1\|790517_791513_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP021105.1\|AVU06319.1\|778501_780487_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP021105.1\|AVU06329.1\|791623_792568_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP021105.1\|AVU06316.1\|776336_777176_+\|peptidase-M23	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42

>CP021105.1|AVU06320.1|780494_783341_+|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKLFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP021105.1|AVU06319.1|778501_780487_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP021105.1|AVU06318.1|777996_778233_+|protein-CsbA
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP021105.1|AVU06317.1|777349_778000_+|hydrolase
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP021105.1|AVU06316.1|776336_777176_+|peptidase-M23
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP021105.1|AVU06315.1|776081_776189_+|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>CP021105.1|AVU06314.1|774932_775928_+|peptide-chain-release-factor-2
MMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP021105.1|AVU06313.1|774544_774649_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>CP021105.1|AVU06312.1|771971_774503_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP021105.1|AVU06311.1|770985_771558_+|ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP021105.1|AVU06321.1|784004_784937_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP021105.1|AVU06322.1|784942_785782_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP021105.1|AVU06323.1|785789_786275_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP021105.1|AVU06324.1|786282_787722_+|hypothetical-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP021105.1|AVU06325.1|787788_788724_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP021105.1|AVU06326.1|789051_789213_-|nitrogen-fixation-protein-NifR
MQVGEGPQHREFRKEILQAMRVGVWAPTQKLTISQLTIMCKLGWYNDKVILFL
>CP021105.1|AVU06327.1|789609_790521_+|RNase-adaptor-protein-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP021105.1|AVU06328.1|790517_791513_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP021105.1|AVU06329.1|791623_792568_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP021105.1|AVU06330.1|793131_793719_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK

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Crispr_ID: CP021105_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_5

789243-789333

Orphan

Consensus_repeat	Method
TCTGTGTTGGGGCCCACACCCCAACTCGCATTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_5

>merge|CP021105|5|789243-789333|CRISPRCasFinder
TCTGTGTTGGGGCCCACACCCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTG

>CP021105|5|5|789243-789333|CRISPRCasFinder
TCTGTGTTGGGGCCCACACCCCAACTCGCATTG	CCTGTAGAATTTCTTTTCGAAATTC
TCTGTGTTGGGGCCCACACCCCAACTTGCATTG

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU06333.1\|797017_798031_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225263
CP021105.1\|AVU06332.1\|795566_796196_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
CP021105.1\|AVU06320.1\|780494_783341_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP021105.1\|AVU06334.1\|798083_799094_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
CP021105.1\|AVU06318.1\|777996_778233_+\|protein-CsbA	unknown	unknown	gnl\|CDD\|227234
CP021105.1\|AVU06336.1\|800544_801306_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP021105.1\|AVU06335.1\|799232_800423_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
CP021105.1\|AVU06317.1\|777349_778000_+\|hydrolase	unknown	unknown	gnl\|CDD\|378993
CP021105.1\|AVU06327.1\|789609_790521_+\|RNase-adaptor-protein-RapZ	unknown	unknown	gnl\|CDD\|224574
CP021105.1\|AVU06325.1\|787788_788724_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP021105.1\|AVU06319.1\|778501_780487_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP021105.1\|AVU06330.1\|793131_793719_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP021105.1\|AVU06322.1\|784942_785782_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP021105.1\|AVU06321.1\|784004_784937_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP021105.1\|AVU06326.1\|789051_789213_-\|nitrogen-fixation-protein-NifR	unknown	unknown	unknown
CP021105.1\|AVU06331.1\|793961_794864_-\|epimerase	unknown	unknown	gnl\|CDD\|224015
CP021105.1\|AVU06323.1\|785789_786275_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP021105.1\|AVU06328.1\|790517_791513_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
CP021105.1\|AVU06324.1\|786282_787722_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276808
CP021105.1\|AVU06329.1\|791623_792568_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU06332.1\|795566_796196_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
CP021105.1\|AVU06320.1\|780494_783341_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP021105.1\|AVU06334.1\|798083_799094_+\|aldehyde-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP021105.1\|AVU06318.1\|777996_778233_+\|protein-CsbA	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP021105.1\|AVU06336.1\|800544_801306_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
CP021105.1\|AVU06335.1\|799232_800423_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
CP021105.1\|AVU06317.1\|777349_778000_+\|hydrolase	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP021105.1\|AVU06327.1\|789609_790521_+\|RNase-adaptor-protein-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP021105.1\|AVU06325.1\|787788_788724_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP021105.1\|AVU06319.1\|778501_780487_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP021105.1\|AVU06330.1\|793131_793719_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP021105.1\|AVU06322.1\|784942_785782_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
CP021105.1\|AVU06321.1\|784004_784937_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP021105.1\|AVU06333.1\|797017_798031_+\|hypothetical-protein	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
CP021105.1\|AVU06331.1\|793961_794864_-\|epimerase	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
CP021105.1\|AVU06323.1\|785789_786275_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
CP021105.1\|AVU06328.1\|790517_791513_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP021105.1\|AVU06324.1\|786282_787722_+\|hypothetical-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP021105.1\|AVU06329.1\|791623_792568_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153

>CP021105.1|AVU06326.1|789051_789213_-|nitrogen-fixation-protein-NifR
MQVGEGPQHREFRKEILQAMRVGVWAPTQKLTISQLTIMCKLGWYNDKVILFL
>CP021105.1|AVU06325.1|787788_788724_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP021105.1|AVU06324.1|786282_787722_+|hypothetical-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP021105.1|AVU06323.1|785789_786275_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP021105.1|AVU06322.1|784942_785782_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP021105.1|AVU06321.1|784004_784937_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP021105.1|AVU06320.1|780494_783341_+|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKLFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP021105.1|AVU06319.1|778501_780487_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP021105.1|AVU06318.1|777996_778233_+|protein-CsbA
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP021105.1|AVU06317.1|777349_778000_+|hydrolase
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP021105.1|AVU06327.1|789609_790521_+|RNase-adaptor-protein-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP021105.1|AVU06328.1|790517_791513_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP021105.1|AVU06329.1|791623_792568_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP021105.1|AVU06330.1|793131_793719_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP021105.1|AVU06331.1|793961_794864_-|epimerase
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>CP021105.1|AVU06332.1|795566_796196_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>CP021105.1|AVU06333.1|797017_798031_+|hypothetical-protein
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>CP021105.1|AVU06334.1|798083_799094_+|aldehyde-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>CP021105.1|AVU06335.1|799232_800423_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>CP021105.1|AVU06336.1|800544_801306_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: CP021105_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_6

833335-833413

Orphan

Consensus_repeat	Method
CAGCTTCTGTGTTGGGGCCCCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_6

>merge|CP021105|6|833335-833413|CRISPRCasFinder
CAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTACCATCAGCTTCTGTGTTGGGGCCCCGC

>CP021105|6|6|833335-833413|CRISPRCasFinder
CAGCTTCTGTGTTGGGGCCCCGC	CAACTTGCACATTATTGTAAGCTGACTTACCAT
CAGCTTCTGTGTTGGGGCCCCGC

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU06377.1\|835608_836304_+\|methionine-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
CP021105.1\|AVU06364.1\|828089_828512_-\|organic-hydroperoxide-reductase-OsmC/OhrA	unknown	unknown	gnl\|CDD\|274649
CP021105.1\|AVU06371.1\|832534_832870_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226395
CP021105.1\|AVU06383.1\|841375_842626_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
CP021105.1\|AVU06363.1\|827196_827691_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
CP021105.1\|AVU06365.1\|828659_829376_+\|3-dehydroquinase	unknown	unknown	gnl\|CDD\|184156
CP021105.1\|AVU06366.1\|829458_829998_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
CP021105.1\|AVU06381.1\|839103_839865_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223473
CP021105.1\|AVU06375.1\|834044_834341_+\|thiol-reductase-thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP021105.1\|AVU06367.1\|830148_830469_-\|thiol-reductase-thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP021105.1\|AVU06380.1\|837924_838776_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
CP021105.1\|AVU06379.1\|837496_837691_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
CP021105.1\|AVU06372.1\|833038_833221_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06378.1\|836321_837143_+\|methionine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
CP021105.1\|AVU06374.1\|833665_834052_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
CP021105.1\|AVU06376.1\|834590_835616_+\|methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP021105.1\|AVU06368.1\|830612_830969_+\|arsenate-reductase	unknown	unknown	gnl\|CDD\|239334
CP021105.1\|AVU06369.1\|831126_831507_+\|glycine-cleavage-system-protein-H	unknown	unknown	gnl\|CDD\|234918
CP021105.1\|AVU06370.1\|831570_831684_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06382.1\|839962_841270_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU06377.1\|835608_836304_+\|methionine-ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	7.66296e-99
CP021105.1\|AVU06364.1\|828089_828512_-\|organic-hydroperoxide-reductase-OsmC/OhrA	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
CP021105.1\|AVU06371.1\|832534_832870_+\|hypothetical-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	6.74308e-31
CP021105.1\|AVU06383.1\|841375_842626_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
CP021105.1\|AVU06363.1\|827196_827691_-\|N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
CP021105.1\|AVU06368.1\|830612_830969_+\|arsenate-reductase	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP021105.1\|AVU06366.1\|829458_829998_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
CP021105.1\|AVU06381.1\|839103_839865_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
CP021105.1\|AVU06375.1\|834044_834341_+\|thiol-reductase-thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP021105.1\|AVU06367.1\|830148_830469_-\|thiol-reductase-thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
CP021105.1\|AVU06380.1\|837924_838776_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	7.67366e-77
CP021105.1\|AVU06379.1\|837496_837691_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
CP021105.1\|AVU06378.1\|836321_837143_+\|methionine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.02861e-112
CP021105.1\|AVU06374.1\|833665_834052_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
CP021105.1\|AVU06376.1\|834590_835616_+\|methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.03316e-170
CP021105.1\|AVU06365.1\|828659_829376_+\|3-dehydroquinase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	3.2619e-146
CP021105.1\|AVU06369.1\|831126_831507_+\|glycine-cleavage-system-protein-H	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
CP021105.1\|AVU06382.1\|839962_841270_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.36148e-135

>CP021105.1|AVU06372.1|833038_833221_+|hypothetical-protein
MHCLQNFFSKFSVLGPLTRIEKSLLQAHFRSVNYCQYNFVEHRTLIYVPACFHKPQLMCI
>CP021105.1|AVU06371.1|832534_832870_+|hypothetical-protein
MLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP021105.1|AVU06370.1|831570_831684_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>CP021105.1|AVU06369.1|831126_831507_+|glycine-cleavage-system-protein-H
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>CP021105.1|AVU06368.1|830612_830969_+|arsenate-reductase
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP021105.1|AVU06367.1|830148_830469_-|thiol-reductase-thioredoxin
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP021105.1|AVU06366.1|829458_829998_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>CP021105.1|AVU06365.1|828659_829376_+|3-dehydroquinase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>CP021105.1|AVU06364.1|828089_828512_-|organic-hydroperoxide-reductase-OsmC/OhrA
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP021105.1|AVU06363.1|827196_827691_-|N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP021105.1|AVU06374.1|833665_834052_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP021105.1|AVU06375.1|834044_834341_+|thiol-reductase-thioredoxin
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP021105.1|AVU06376.1|834590_835616_+|methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP021105.1|AVU06377.1|835608_836304_+|methionine-ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP021105.1|AVU06378.1|836321_837143_+|methionine-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP021105.1|AVU06379.1|837496_837691_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>CP021105.1|AVU06380.1|837924_838776_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>CP021105.1|AVU06381.1|839103_839865_+|ABC-transporter-ATP-binding-protein
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>CP021105.1|AVU06382.1|839962_841270_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>CP021105.1|AVU06383.1|841375_842626_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF

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Crispr_ID: CP021105_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_7

1101746-1101826

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAGGCAATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_7

>merge|CP021105|7|1101746-1101826|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCGAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGC

>CP021105|7|7|1101746-1101826|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGC	GAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCA
AAAAGAAATTCTACAGACAATGC

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU06639.1\|1108806_1109034_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06629.1\|1097326_1097560_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06641.1\|1110535_1110724_+\|DNA-binding-protein	unknown	unknown	unknown
CP021105.1\|AVU06631.1\|1099556_1100516_-\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
CP021105.1\|AVU06635.1\|1102832_1103558_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|106307
CP021105.1\|AVU06638.1\|1105839_1106772_+\|carbamate-kinase-1	unknown	unknown	gnl\|CDD\|237071
CP021105.1\|AVU06633.1\|1101291_1101516_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU08213.1\|1096114_1096369_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06627.1\|1095402_1095753_+\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|371594
CP021105.1\|AVU06626.1\|1094755_1095253_+\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|289007
CP021105.1\|AVU06636.1\|1103652_1104378_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|171855
CP021105.1\|AVU06632.1\|1101188_1101335_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06634.1\|1102008_1102725_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|171995
CP021105.1\|AVU06630.1\|1098078_1099398_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
CP021105.1\|AVU08214.1\|1096914_1097133_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU06642.1\|1111628_1111763_+\|hemolytic-protein	unknown	unknown	gnl\|CDD\|368464
CP021105.1\|AVU06640.1\|1109339_1110287_-\|permease	unknown	unknown	gnl\|CDD\|187765
CP021105.1\|AVU08215.1\|1107009_1108500_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224207
CP021105.1\|AVU06637.1\|1104815_1105817_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
CP021105.1\|AVU06628.1\|1096519_1096705_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU06626.1\|1094755_1095253_+\|fibrinogen-binding-protein	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.84801e-27
CP021105.1\|AVU06631.1\|1099556_1100516_-\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.66722e-141
CP021105.1\|AVU06635.1\|1102832_1103558_-\|hypothetical-protein	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	3.51282e-147
CP021105.1\|AVU06638.1\|1105839_1106772_+\|carbamate-kinase-1	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
CP021105.1\|AVU06640.1\|1109339_1110287_-\|permease	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.38933e-84
CP021105.1\|AVU06630.1\|1098078_1099398_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.75686e-114
CP021105.1\|AVU06636.1\|1103652_1104378_-\|hypothetical-protein	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	1.6289e-161
CP021105.1\|AVU06634.1\|1102008_1102725_-\|hypothetical-protein	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	2.65762e-152
CP021105.1\|AVU06627.1\|1095402_1095753_+\|fibrinogen-binding-protein	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
CP021105.1\|AVU06642.1\|1111628_1111763_+\|hemolytic-protein	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
CP021105.1\|AVU08215.1\|1107009_1108500_+\|hypothetical-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
CP021105.1\|AVU06637.1\|1104815_1105817_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0

>CP021105.1|AVU06633.1|1101291_1101516_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>CP021105.1|AVU06632.1|1101188_1101335_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>CP021105.1|AVU06631.1|1099556_1100516_-|alpha-hemolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>CP021105.1|AVU06630.1|1098078_1099398_+|ISL3-family-transposase
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPNYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRRSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKVVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA
>CP021105.1|AVU06629.1|1097326_1097560_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>CP021105.1|AVU08214.1|1096914_1097133_-|hypothetical-protein
MINFGLIIVPLLTTNDADFVWTSSSLIYMILLTSIILIVYIKTKDSLQLTIFILNIALIILYCAPLLFIYVF
>CP021105.1|AVU06628.1|1096519_1096705_-|hypothetical-protein
MNKHINKKATKLLEDYKKVQQRKSEETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>CP021105.1|AVU08213.1|1096114_1096369_+|hypothetical-protein
MQVGVGPQQREIGSPIPTDNASWRGPNIEKLDHQFQQTMQVGVGPNTEAGEKSAYKNVQVGVGPNTEAGEKSAYKNVQVGVGHR
>CP021105.1|AVU06627.1|1095402_1095753_+|fibrinogen-binding-protein
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>CP021105.1|AVU06626.1|1094755_1095253_+|fibrinogen-binding-protein
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVR
>CP021105.1|AVU06634.1|1102008_1102725_-|hypothetical-protein
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>CP021105.1|AVU06635.1|1102832_1103558_-|hypothetical-protein
MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>CP021105.1|AVU06636.1|1103652_1104378_-|hypothetical-protein
MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKSN
>CP021105.1|AVU06637.1|1104815_1105817_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>CP021105.1|AVU06638.1|1105839_1106772_+|carbamate-kinase-1
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>CP021105.1|AVU08215.1|1107009_1108500_+|hypothetical-protein
MILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPSGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>CP021105.1|AVU06639.1|1108806_1109034_+|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>CP021105.1|AVU06640.1|1109339_1110287_-|permease
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKENQDKFLRNASQ
>CP021105.1|AVU06641.1|1110535_1110724_+|DNA-binding-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSNEN
>CP021105.1|AVU06642.1|1111628_1111763_+|hemolytic-protein
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF

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Crispr_ID: CP021105_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_8

1574012-1574096

Orphan

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_8

>merge|CP021105|8|1574012-1574096|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>CP021105|8|8|1574012-1574096|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTGTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU07050.1\|1570843_1571470_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237622
CP021105.1\|AVU07055.1\|1577764_1579912_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
CP021105.1\|AVU07047.1\|1566725_1567664_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
CP021105.1\|AVU07045.1\|1564618_1565965_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
CP021105.1\|AVU07060.1\|1582322_1582907_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|224627
CP021105.1\|AVU08230.1\|1572578_1573703_-\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP021105.1\|AVU07056.1\|1579970_1580432_-\|ComE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
CP021105.1\|AVU07052.1\|1574268_1576092_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP021105.1\|AVU07061.1\|1582896_1583466_-\|nicotinate-nicotinamide-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
CP021105.1\|AVU07051.1\|1571501_1572479_-\|HrcA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|273017
CP021105.1\|AVU07059.1\|1581968_1582322_-\|ribosome-silencing-factor-RsfS	unknown	unknown	gnl\|CDD\|223870
CP021105.1\|AVU08229.1\|1563222_1563906_-\|serine-protease	unknown	unknown	gnl\|CDD\|223961
CP021105.1\|AVU07049.1\|1568942_1570775_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
CP021105.1\|AVU07058.1\|1581249_1581966_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP021105.1\|AVU07053.1\|1576437_1576689_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
CP021105.1\|AVU07057.1\|1580523_1581210_-\|competence-protein-ComE	unknown	unknown	gnl\|CDD\|224472
CP021105.1\|AVU07044.1\|1564149_1564326_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
CP021105.1\|AVU07046.1\|1565971_1566724_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
CP021105.1\|AVU07054.1\|1576733_1577708_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
CP021105.1\|AVU07048.1\|1567667_1568807_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237656

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU07050.1\|1570843_1571470_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
CP021105.1\|AVU07055.1\|1577764_1579912_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.49563e-90
CP021105.1\|AVU07047.1\|1566725_1567664_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.7051e-134
CP021105.1\|AVU07045.1\|1564618_1565965_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
CP021105.1\|AVU07060.1\|1582322_1582907_-\|HAD-family-hydrolase	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
CP021105.1\|AVU08230.1\|1572578_1573703_-\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP021105.1\|AVU07056.1\|1579970_1580432_-\|ComE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
CP021105.1\|AVU07052.1\|1574268_1576092_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP021105.1\|AVU07061.1\|1582896_1583466_-\|nicotinate-nicotinamide-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.64141e-76
CP021105.1\|AVU07051.1\|1571501_1572479_-\|HrcA-family-transcriptional-regulator	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119
CP021105.1\|AVU07059.1\|1581968_1582322_-\|ribosome-silencing-factor-RsfS	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47
CP021105.1\|AVU08229.1\|1563222_1563906_-\|serine-protease	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	8.78003e-63
CP021105.1\|AVU07049.1\|1568942_1570775_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
CP021105.1\|AVU07058.1\|1581249_1581966_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.79783e-16
CP021105.1\|AVU07053.1\|1576437_1576689_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17
CP021105.1\|AVU07057.1\|1580523_1581210_-\|competence-protein-ComE	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	1.06297e-33
CP021105.1\|AVU07044.1\|1564149_1564326_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
CP021105.1\|AVU07046.1\|1565971_1566724_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.90273e-91
CP021105.1\|AVU07054.1\|1576733_1577708_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	4.1415e-104
CP021105.1\|AVU07048.1\|1567667_1568807_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0

>CP021105.1|AVU08230.1|1572578_1573703_-|coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>CP021105.1|AVU07051.1|1571501_1572479_-|HrcA-family-transcriptional-regulator
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>CP021105.1|AVU07050.1|1570843_1571470_-|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>CP021105.1|AVU07049.1|1568942_1570775_-|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>CP021105.1|AVU07048.1|1567667_1568807_-|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>CP021105.1|AVU07047.1|1566725_1567664_-|50S-ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>CP021105.1|AVU07046.1|1565971_1566724_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>CP021105.1|AVU07045.1|1564618_1565965_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>CP021105.1|AVU07044.1|1564149_1564326_-|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>CP021105.1|AVU08229.1|1563222_1563906_-|serine-protease
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>CP021105.1|AVU07052.1|1574268_1576092_-|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>CP021105.1|AVU07053.1|1576437_1576689_+|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>CP021105.1|AVU07054.1|1576733_1577708_-|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>CP021105.1|AVU07055.1|1577764_1579912_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLSTFLFILLLYITYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>CP021105.1|AVU07056.1|1579970_1580432_-|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>CP021105.1|AVU07057.1|1580523_1581210_-|competence-protein-ComE
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI
>CP021105.1|AVU07058.1|1581249_1581966_-|SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDTERLFFIAKK
>CP021105.1|AVU07059.1|1581968_1582322_-|ribosome-silencing-factor-RsfS
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>CP021105.1|AVU07060.1|1582322_1582907_-|HAD-family-hydrolase
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>CP021105.1|AVU07061.1|1582896_1583466_-|nicotinate-nicotinamide-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

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Crispr_ID: CP021105_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_9

2003066-2003147

Orphan

Consensus_repeat	Method
GGCCCCCACCCCAACTTACATTGT	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP021105_9

>merge|CP021105|9|2003066-2003147|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCCACCCCAACTTGCATTGT

>CP021105|9|9|2003066-2003147|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGG
GGCCCCCACCCCAACTTGCATTGT

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU07462.1\|1994810_1995152_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU07472.1\|2005592_2006315_+\|exotoxin	unknown	unknown	gnl\|CDD\|280949
CP021105.1\|AVU07477.1\|2010934_2011276_-\|pathogenicity-island-protein	unknown	unknown	unknown
CP021105.1\|AVU07470.1\|2001621_2002845_+\|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|181490
CP021105.1\|AVU07474.1\|2008071_2008632_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|294014
CP021105.1\|AVU07467.1\|1998030_1998855_+\|sphingomyelin-phosphodiesterase	unknown	unknown	gnl\|CDD\|132436
CP021105.1\|AVU07476.1\|2010368_2010938_-\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|226251
CP021105.1\|AVU07475.1\|2009509_2010214_+\|toxin	unknown	unknown	gnl\|CDD\|171853
CP021105.1\|AVU07465.1\|1996631_1996874_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU07468.1\|1999092_2000109_-\|gamma-hemolysin-subunit-B	unknown	unknown	gnl\|CDD\|369625
CP021105.1\|AVU07469.1\|2000130_2001186_-\|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|369625
CP021105.1\|AVU07471.1\|2003288_2004596_+\|potassium-transporter-KtrB	unknown	unknown	gnl\|CDD\|273349
CP021105.1\|AVU07466.1\|1996936_1997974_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP021105.1\|AVU07461.1\|1993872_1994805_+\|ATP-dependent-helicase	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235735
CP021105.1\|AVU07463.1\|1995355_1995538_+\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU07478.1\|2011278_2011806_-\|spore-coat-protein	unknown	unknown	gnl\|CDD\|227864
CP021105.1\|AVU07473.1\|2006483_2007284_-\|enterotoxin	unknown	unknown	gnl\|CDD\|280949
CP021105.1\|AVU07464.1\|1995637_1996621_+\|glycosyl-transferase-family-A	unknown	unknown	gnl\|CDD\|366154
CP021105.1\|AVU07479.1\|2011856_2012075_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374753
CP021105.1\|AVU07480.1\|2012092_2012671_-\|pathogenicity-island-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU07472.1\|2005592_2006315_+\|exotoxin	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	5.47389e-31
CP021105.1\|AVU07479.1\|2011856_2012075_-\|hypothetical-protein	gnl\|CDD\|374753	pfam16722, SAPIS-gp6, Pathogenicity island protein gp6 in Staphylococcus. SAPIS-gp6 is a family of proteins produced from the pathogenicity island SAPI1 in pathogenic Staphylococcus aureus. This is a mobile genetic element that carries genes for several superantigen toxins. SAPIS-gp6 is a dimeric protein produced from the pathogenicity island with a helix-loop-helix motif similar to that of bacteriophage scaffolding proteins. It is thought to determine the size of the capsids of distribution of the SAPI1 genome as it acts as an internal scaffolding protein during capsid size determination.	1.50939e-18
CP021105.1\|AVU07470.1\|2001621_2002845_+\|succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
CP021105.1\|AVU07474.1\|2008071_2008632_+\|hypothetical-protein	gnl\|CDD\|294014	cd15783, SA1633_like, Uncharacterized protein family conserved in Staphylococci. Some proteins in this family have been described as putative beta-lactamases. They are structurally similar to the C-terminal beta-grasp domains of Staphylococcal and Streptococcal superantigens.	1.47157e-43
CP021105.1\|AVU07476.1\|2010368_2010938_-\|terminase-small-subunit	gnl\|CDD\|226251	COG3728, XtmA, Phage terminase, small subunit [DNA replication, recombination, and repair].	1.62287e-69
CP021105.1\|AVU07467.1\|1998030_1998855_+\|sphingomyelin-phosphodiesterase	gnl\|CDD\|132436	TIGR03395, Sphingomyelinase_C, sphingomyelin phosphodiesterase. Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. [Cellular processes, Pathogenesis].	2.2954e-127
CP021105.1\|AVU07468.1\|1999092_2000109_-\|gamma-hemolysin-subunit-B	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.05827e-99
CP021105.1\|AVU07469.1\|2000130_2001186_-\|succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.84035e-77
CP021105.1\|AVU07471.1\|2003288_2004596_+\|potassium-transporter-KtrB	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	7.96864e-82
CP021105.1\|AVU07466.1\|1996936_1997974_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.76637e-25
CP021105.1\|AVU07461.1\|1993872_1994805_+\|ATP-dependent-helicase	gnl\|CDD\|235735	PRK06195, PRK06195, DNA polymerase III subunit epsilon; Validated.	1.68456e-42
CP021105.1\|AVU07475.1\|2009509_2010214_+\|toxin	gnl\|CDD\|171853	PRK13038, PRK13038, superantigen-like protein; Reviewed.	1.96896e-09
CP021105.1\|AVU07478.1\|2011278_2011806_-\|spore-coat-protein	gnl\|CDD\|227864	COG5577, COG5577, Spore coat protein [Cell envelope biogenesis, outer membrane].	5.49894e-35
CP021105.1\|AVU07473.1\|2006483_2007284_-\|enterotoxin	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.74895e-25
CP021105.1\|AVU07464.1\|1995637_1996621_+\|glycosyl-transferase-family-A	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	3.06668e-26

>CP021105.1|AVU07470.1|2001621_2002845_+|succinyl-diaminopimelate-desuccinylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>CP021105.1|AVU07469.1|2000130_2001186_-|succinyl-diaminopimelate-desuccinylase
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>CP021105.1|AVU07468.1|1999092_2000109_-|gamma-hemolysin-subunit-B
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>CP021105.1|AVU07467.1|1998030_1998855_+|sphingomyelin-phosphodiesterase
MYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
>CP021105.1|AVU07466.1|1996936_1997974_+|site-specific-integrase
MKTRCYDGKKWQYEFKHEGKRYRKKGFRTKREANSAGLDKLNELRSGFNIDNYITLEEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINRQVYQKFINDHSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTDTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEAGSIINLQAINNALKSACRVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM
>CP021105.1|AVU07465.1|1996631_1996874_+|hypothetical-protein
MENFNYNNIKKLVLENVDIDKVKEVYKDYELLNYTIKNQTLYMNDYEVAKVSEKHLNENINNLRGTVNLDEKCILSLTYL
>CP021105.1|AVU07464.1|1995637_1996621_+|glycosyl-transferase-family-A
MKKVSVIMPTFNNGEKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETLNVIKKYKGLVRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHERALEDLYNYGKENNSDLIIGKYGVEGKGRSVPKAIFEKGNVAKADIIDNSIFYALSVLKMFKKSVIDKNKIKFKTFSKTAEDQLFTIEFLMNSKNYSIKTDYEYYIVVNDFESSNHLSVNKSTGNQYFATINEIYKAIYKSPIYKNQEKRHQLAGKYTTRLLRHGQKKNFANSKMKYEDKIEWLNNFSKTINKVPRDSDKYVTQIFNLKLEAIRQNDLLAVMIADKLL
>CP021105.1|AVU07463.1|1995355_1995538_+|hypothetical-protein
MKIKNCKIKKETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEFISQKLDGDKLTKEDSL
>CP021105.1|AVU07462.1|1994810_1995152_+|hypothetical-protein
MIKKIFTKKHVFLVIEDENHNHSDAVFGKSILLSIYVGVNKKTNSKSGKFIYLDRSKRIVRQSDITKIESANENDVDFYNLLKKEKEIVYSKNIVDKYNLANYIIYYEVSTKE
>CP021105.1|AVU07461.1|1993872_1994805_+|ATP-dependent-helicase
MKKYDIAVLDFETMNEHMNSPCEVAVSLIKDLSIVKVYSSYINPPNNRYNLKNAKIHKIPEDVILKAPKYPDIYQEILYLLKESHLIIAHNALFDISVLKNTNNYYDLPVPNFMYVDSINIFRSFHAISSFKLENLCSLYDIDKEKLHSAKFDVLALSKMLISLAKNNQHYSVLKLIHYMPKQYIRFSKYSNSPTKLFDSGFQKIHMKISEINKIEVESVIPILKDKNVVFTGNFDTEKQDLMILTRKKGAYIRSDVTAKTDILVEGVQDDKYKDVNGLVSKQRKAREYVGNGAKIQFLNEEDLINLIKE
>CP021105.1|AVU07471.1|2003288_2004596_+|potassium-transporter-KtrB
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>CP021105.1|AVU07472.1|2005592_2006315_+|exotoxin
MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVNLKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDVFGISYKYGSNSRTIYGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQDEFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGFPESFLKIYKDNKTVDSTQFHLDVEISKR
>CP021105.1|AVU07473.1|2006483_2007284_-|enterotoxin
MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG
>CP021105.1|AVU07474.1|2008071_2008632_+|hypothetical-protein
MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTDNALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINPQNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGKVGEDKSNVSNRYINPKDINEIQITKK
>CP021105.1|AVU07475.1|2009509_2010214_+|toxin
MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEIN
>CP021105.1|AVU07476.1|2010368_2010938_-|terminase-small-subunit
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKIIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELIEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEELDKTVQEVSNANPNHTVIVDDIPLED
>CP021105.1|AVU07477.1|2010934_2011276_-|pathogenicity-island-protein
MDKKQIKDFVCDYHERTRSDVLIDDEINTDEFFSIGDENSNEWMADDNIDDHIVRNHLEMIVDRVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYETLLDKIVEVIE
>CP021105.1|AVU07478.1|2011278_2011806_-|spore-coat-protein
MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPTFINKKIRMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKARLQNYKNRSISNMALLKNVLNFYTEKEQKKVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSHVKVV
>CP021105.1|AVU07479.1|2011856_2012075_-|hypothetical-protein
METKYELNNTKKVANAFGLNEEDTNLLINAVDLDIKNNMQEISSELQQSEQSKQKQYGTTLQNLAKQNRIIK
>CP021105.1|AVU07480.1|2012092_2012671_-|pathogenicity-island-protein
MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKLDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP021105_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_10

2143600-2143680

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP021105_10

>merge|CP021105|10|2143600-2143680|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>CP021105|10|10|2143600-2143680|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU07602.1\|2138364_2139303_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
CP021105.1\|AVU07600.1\|2136058_2137432_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
CP021105.1\|AVU07609.1\|2145394_2145487_+\|erm-Leader-peptide	unknown	unknown	unknown
CP021105.1\|AVU07597.1\|2133714_2134425_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP021105.1\|AVU07610.1\|2145615_2146473_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
CP021105.1\|AVU07596.1\|2132738_2133401_-\|2-deoxyribose-5-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
CP021105.1\|AVU07611.1\|2146540_2147323_-\|iron-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
CP021105.1\|AVU07598.1\|2134545_2134989_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
CP021105.1\|AVU07607.1\|2144552_2144735_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU07599.1\|2135188_2135602_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225556
CP021105.1\|AVU07614.1\|2151613_2153746_+\|PTS-lactose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226234
CP021105.1\|AVU07612.1\|2147554_2149360_-\|glutamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP021105.1\|AVU07613.1\|2150040_2151579_+\|PTS-mannitol-transporter-subunit-IICBA	unknown	unknown	gnl\|CDD\|225123
CP021105.1\|AVU07608.1\|2144799_2144958_+\|integrase	unknown	unknown	unknown
CP021105.1\|AVU07601.1\|2138103_2138334_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU07615.1\|2153757_2154192_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP021105.1\|AVU07604.1\|2140555_2140876_+\|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP021105.1\|AVU07605.1\|2140877_2141855_+\|cation-efflux-pump	unknown	unknown	gnl\|CDD\|224151
CP021105.1\|AVU07603.1\|2139738_2140404_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|187554
CP021105.1\|AVU07606.1\|2144015_2144120_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU07602.1\|2138364_2139303_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP021105.1\|AVU07600.1\|2136058_2137432_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	4.11455e-06
CP021105.1\|AVU07597.1\|2133714_2134425_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
CP021105.1\|AVU07596.1\|2132738_2133401_-\|2-deoxyribose-5-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	1.39422e-127
CP021105.1\|AVU07611.1\|2146540_2147323_-\|iron-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
CP021105.1\|AVU07598.1\|2134545_2134989_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP021105.1\|AVU07599.1\|2135188_2135602_-\|hypothetical-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP021105.1\|AVU07614.1\|2151613_2153746_+\|PTS-lactose-transporter-subunit-IIB	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
CP021105.1\|AVU07612.1\|2147554_2149360_-\|glutamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP021105.1\|AVU07610.1\|2145615_2146473_-\|HAD-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
CP021105.1\|AVU07615.1\|2153757_2154192_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP021105.1\|AVU07613.1\|2150040_2151579_+\|PTS-mannitol-transporter-subunit-IICBA	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP021105.1\|AVU07605.1\|2140877_2141855_+\|cation-efflux-pump	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	5.81737e-107
CP021105.1\|AVU07603.1\|2139738_2140404_-\|oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
CP021105.1\|AVU07604.1\|2140555_2140876_+\|transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17

>CP021105.1|AVU07605.1|2140877_2141855_+|cation-efflux-pump
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASTLVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP021105.1|AVU07604.1|2140555_2140876_+|transcriptional-regulator
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP021105.1|AVU07603.1|2139738_2140404_-|oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>CP021105.1|AVU07602.1|2138364_2139303_-|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP021105.1|AVU07601.1|2138103_2138334_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP021105.1|AVU07600.1|2136058_2137432_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP021105.1|AVU07599.1|2135188_2135602_-|hypothetical-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP021105.1|AVU07598.1|2134545_2134989_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP021105.1|AVU07597.1|2133714_2134425_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP021105.1|AVU07596.1|2132738_2133401_-|2-deoxyribose-5-phosphate-aldolase
MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY
>CP021105.1|AVU07606.1|2144015_2144120_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>CP021105.1|AVU07607.1|2144552_2144735_-|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>CP021105.1|AVU07608.1|2144799_2144958_+|integrase
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP021105.1|AVU07609.1|2145394_2145487_+|erm-Leader-peptide
MTYGSIVAILCALFVIFFIPYMEKKDKKKK
>CP021105.1|AVU07610.1|2145615_2146473_-|HAD-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP021105.1|AVU07611.1|2146540_2147323_-|iron-ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP021105.1|AVU07612.1|2147554_2149360_-|glutamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP021105.1|AVU07613.1|2150040_2151579_+|PTS-mannitol-transporter-subunit-IICBA
MSQTEEKKGIGRRVQAFGSFLSSMIMPNVGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVPSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP021105.1|AVU07614.1|2151613_2153746_+|PTS-lactose-transporter-subunit-IIB
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP021105.1|AVU07615.1|2153757_2154192_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA

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Crispr_ID: CP021105_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021105_11

2155921-2156006

Orphan

Consensus_repeat	Method
CCAACTGATTTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP021105_11

>merge|CP021105|11|2155921-2156006|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGGGCCAACTGATTTTTGCGTATCATTAGT

>CP021105|11|11|2155921-2156006|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGGG
CCAACTGATTTTTGCGTATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
CP021105.1\|AVU07621.1\|2173804_2174869_-\|chromosome-partitioning-protein-ParA	unknown	unknown	gnl\|CDD\|378455
CP021105.1\|AVU07617.1\|2163339_2164695_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
CP021105.1\|AVU07623.1\|2176781_2177255_-\|multidrug-resistance-efflux-pump-SepA	unknown	unknown	gnl\|CDD\|374975
CP021105.1\|AVU07609.1\|2145394_2145487_+\|erm-Leader-peptide	unknown	unknown	unknown
CP021105.1\|AVU07625.1\|2178873_2179557_-\|hemolysin-III	unknown	unknown	gnl\|CDD\|224191
CP021105.1\|AVU07618.1\|2164721_2165654_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227193
CP021105.1\|AVU07616.1\|2154191_2155298_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP021105.1\|AVU07620.1\|2166653_2167562_-\|arginase	unknown	unknown	gnl\|CDD\|212515
CP021105.1\|AVU07622.1\|2175016_2176459_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
CP021105.1\|AVU07611.1\|2146540_2147323_-\|iron-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
CP021105.1\|AVU07626.1\|2179575_2180763_-\|uridylyltransferase	unknown	unknown	gnl\|CDD\|133036
CP021105.1\|AVU07619.1\|2165655_2166465_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
CP021105.1\|AVU07607.1\|2144552_2144735_-\|hypothetical-protein	unknown	unknown	unknown
CP021105.1\|AVU07614.1\|2151613_2153746_+\|PTS-lactose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226234
CP021105.1\|AVU07610.1\|2145615_2146473_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
CP021105.1\|AVU07615.1\|2153757_2154192_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP021105.1\|AVU07613.1\|2150040_2151579_+\|PTS-mannitol-transporter-subunit-IICBA	unknown	unknown	gnl\|CDD\|225123
CP021105.1\|AVU07624.1\|2177353_2178697_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
CP021105.1\|AVU07612.1\|2147554_2149360_-\|glutamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP021105.1\|AVU07608.1\|2144799_2144958_+\|integrase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP021105.1\|AVU07617.1\|2163339_2164695_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP021105.1\|AVU07623.1\|2176781_2177255_-\|multidrug-resistance-efflux-pump-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
CP021105.1\|AVU07621.1\|2173804_2174869_-\|chromosome-partitioning-protein-ParA	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
CP021105.1\|AVU07625.1\|2178873_2179557_-\|hemolysin-III	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
CP021105.1\|AVU07618.1\|2164721_2165654_-\|hypothetical-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	7.0606e-117
CP021105.1\|AVU07616.1\|2154191_2155298_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP021105.1\|AVU07620.1\|2166653_2167562_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	9.8301e-146
CP021105.1\|AVU07622.1\|2175016_2176459_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.85929e-81
CP021105.1\|AVU07611.1\|2146540_2147323_-\|iron-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
CP021105.1\|AVU07626.1\|2179575_2180763_-\|uridylyltransferase	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
CP021105.1\|AVU07619.1\|2165655_2166465_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
CP021105.1\|AVU07614.1\|2151613_2153746_+\|PTS-lactose-transporter-subunit-IIB	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
CP021105.1\|AVU07610.1\|2145615_2146473_-\|HAD-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
CP021105.1\|AVU07615.1\|2153757_2154192_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP021105.1\|AVU07624.1\|2177353_2178697_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.95508e-43
CP021105.1\|AVU07612.1\|2147554_2149360_-\|glutamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP021105.1\|AVU07613.1\|2150040_2151579_+\|PTS-mannitol-transporter-subunit-IICBA	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0

>CP021105.1|AVU07616.1|2154191_2155298_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP021105.1|AVU07615.1|2153757_2154192_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP021105.1|AVU07614.1|2151613_2153746_+|PTS-lactose-transporter-subunit-IIB
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP021105.1|AVU07613.1|2150040_2151579_+|PTS-mannitol-transporter-subunit-IICBA
MSQTEEKKGIGRRVQAFGSFLSSMIMPNVGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVPSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP021105.1|AVU07612.1|2147554_2149360_-|glutamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP021105.1|AVU07611.1|2146540_2147323_-|iron-ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP021105.1|AVU07610.1|2145615_2146473_-|HAD-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP021105.1|AVU07609.1|2145394_2145487_+|erm-Leader-peptide
MTYGSIVAILCALFVIFFIPYMEKKDKKKK
>CP021105.1|AVU07608.1|2144799_2144958_+|integrase
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP021105.1|AVU07607.1|2144552_2144735_-|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>CP021105.1|AVU07617.1|2163339_2164695_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>CP021105.1|AVU07618.1|2164721_2165654_-|hypothetical-protein
MLESKWGLRFIVFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>CP021105.1|AVU07619.1|2165655_2166465_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>CP021105.1|AVU07620.1|2166653_2167562_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>CP021105.1|AVU07621.1|2173804_2174869_-|chromosome-partitioning-protein-ParA
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>CP021105.1|AVU07622.1|2175016_2176459_-|MFS-transporter
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNVLLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>CP021105.1|AVU07623.1|2176781_2177255_-|multidrug-resistance-efflux-pump-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>CP021105.1|AVU07624.1|2177353_2178697_-|MFS-transporter
MRLKSIITVIALILFMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>CP021105.1|AVU07625.1|2178873_2179557_-|hemolysin-III
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>CP021105.1|AVU07626.1|2179575_2180763_-|uridylyltransferase
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP021105_1	1.1\|154001\|33\|CP021105\|CRISPRCasFinder	154001-154033	33	CP021105.1	1307822-1307854	0	1.0
CP021105_4	4.1\|783692\|31\|CP021105\|CRISPRCasFinder	783692-783722	31	CP021105.1	277173-277203	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	153959-153983	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	277095-277119	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	277205-277229	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	617252-617276	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	741762-741786	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	789159-789183	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	1101738-1101762	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	1307722-1307746	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	1574088-1574112	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	1588619-1588643	0	1.0
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	1900546-1900570	0	1.0
CP021105_9	9.1\|2003090\|34\|CP021105\|CRISPRCasFinder	2003090-2003123	34	CP021105.1	783667-783700	0	1.0
CP021105_9	9.1\|2003090\|34\|CP021105\|CRISPRCasFinder	2003090-2003123	34	CP021105.1	1096078-1096111	0	1.0
CP021105_1	1.1\|154001\|33\|CP021105\|CRISPRCasFinder	154001-154033	33	CP021105.1	832998-833030	1	0.97
CP021105_4	4.1\|783692\|31\|CP021105\|CRISPRCasFinder	783692-783722	31	CP021105.1	277118-277148	1	0.968
CP021105_4	4.1\|783692\|31\|CP021105\|CRISPRCasFinder	783692-783722	31	CP021105.1	1608494-1608524	1	0.968
CP021105_4	4.1\|783692\|31\|CP021105\|CRISPRCasFinder	783692-783722	31	CP021105.1	1608550-1608580	1	0.968
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	277150-277174	1	0.96
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	833047-833071	1	0.96
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	903092-903116	1	0.96
CP021105_5	5.1\|789276\|25\|CP021105\|CRISPRCasFinder	789276-789300	25	CP021105.1	1608349-1608373	1	0.96
CP021105_8	8.1\|1574038\|33\|CP021105\|CRISPRCasFinder	1574038-1574070	33	CP021105.1	1307822-1307854	1	0.97
CP021105_9	9.1\|2003090\|34\|CP021105\|CRISPRCasFinder	2003090-2003123	34	CP021105.1	1694160-1694193	1	0.971
CP021105_1	1.1\|154001\|33\|CP021105\|CRISPRCasFinder	154001-154033	33	CP021105.1	1396088-1396120	2	0.939
CP021105_8	8.1\|1574038\|33\|CP021105\|CRISPRCasFinder	1574038-1574070	33	CP021105.1	832998-833030	2	0.939
CP021105_9	9.1\|2003090\|34\|CP021105\|CRISPRCasFinder	2003090-2003123	34	CP021105.1	1312195-1312228	2	0.941
CP021105_9	9.1\|2003090\|34\|CP021105\|CRISPRCasFinder	2003090-2003123	34	CP021105.1	2704999-2705032	2	0.941

1. spacer 1.1|154001|33|CP021105|CRISPRCasFinder matches to position: 1307822-1307854, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

2. spacer 4.1|783692|31|CP021105|CRISPRCasFinder matches to position: 277173-277203, mismatch: 0, identity: 1.0

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattgcc	Protospacer
*******************************

3. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 153959-153983, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

4. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 277095-277119, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

5. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 277205-277229, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

6. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 617252-617276, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

7. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 741762-741786, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

8. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 789159-789183, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

9. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 1101738-1101762, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

10. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 1307722-1307746, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

11. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 1574088-1574112, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

12. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 1588619-1588643, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

13. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 1900546-1900570, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

14. spacer 9.1|2003090|34|CP021105|CRISPRCasFinder matches to position: 783667-783700, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

15. spacer 9.1|2003090|34|CP021105|CRISPRCasFinder matches to position: 1096078-1096111, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

16. spacer 1.1|154001|33|CP021105|CRISPRCasFinder matches to position: 832998-833030, mismatch: 1, identity: 0.97

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattctcaat	Protospacer
****************************.****

17. spacer 4.1|783692|31|CP021105|CRISPRCasFinder matches to position: 277118-277148, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattacc	Protospacer
****************************.**

18. spacer 4.1|783692|31|CP021105|CRISPRCasFinder matches to position: 1608494-1608524, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttccattgcc	Protospacer
*********************** *******

19. spacer 4.1|783692|31|CP021105|CRISPRCasFinder matches to position: 1608550-1608580, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttccattgcc	Protospacer
*********************** *******

20. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 277150-277174, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaatttc	Protospacer
********************* ***

21. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 833047-833071, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgcagaatttcttttcgaaattc	Protospacer
****.********************

22. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 903092-903116, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttagaaattc	Protospacer
***************** *******

23. spacer 5.1|789276|25|CP021105|CRISPRCasFinder matches to position: 1608349-1608373, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttctttacgaaattc	Protospacer
**************** ********

24. spacer 8.1|1574038|33|CP021105|CRISPRCasFinder matches to position: 1307822-1307854, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

25. spacer 9.1|2003090|34|CP021105|CRISPRCasFinder matches to position: 1694160-1694193, mismatch: 1, identity: 0.971

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttgtgttgg	Protospacer
*************************.********

26. spacer 1.1|154001|33|CP021105|CRISPRCasFinder matches to position: 1396088-1396120, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tggaccccaacaaagagaaattgtattcccaat	Protospacer
***.******************* *********

27. spacer 8.1|1574038|33|CP021105|CRISPRCasFinder matches to position: 832998-833030, mismatch: 2, identity: 0.939

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgagaatccaatttctctttgttggggccca	Protospacer
****.*************** ************

28. spacer 9.1|2003090|34|CP021105|CRISPRCasFinder matches to position: 1312195-1312228, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtggaatttcttatcgaaattctctgtgttgg	Protospacer
****.********* *******************

29. spacer 9.1|2003090|34|CP021105|CRISPRCasFinder matches to position: 2704999-2705032, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttttgttgg	Protospacer
*************************.* ******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP021105_11	11.1\|2155947\|34\|CP021105\|CRISPRCasFinder	2155947-2155980	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
CP021105_11	11.1\|2155947\|34\|CP021105\|CRISPRCasFinder	2155947-2155980	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 11.1|2155947|34|CP021105|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

2. spacer 11.1|2155947|34|CP021105|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

720840 : 728661

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU06259.1\|720840_721896_-	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
AVU06260.1\|721895_722582_-	DNA-binding response regulator	NA	NA	NA	NA
AVU06261.1\|722556_723030_-	DoxX family protein	NA	NA	NA	NA
AVU06262.1\|723372_723813_-	hypothetical protein	NA	NA	NA	NA
AVU06263.1\|724092_724677_-	hypothetical protein	NA	NA	NA	NA
AVU06264.1\|724775_725489_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AVU06265.1\|725492_725912_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	1.8e-06	27.6
AVU06266.1\|725913_726582_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AVU06267.1\|726932_727526_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AVU06268.1\|727509_728661_+	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	6.0e-23	35.7

DBSCAN-SWA_2

740632 : 755273

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU06278.1\|740632_741691_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
AVU06279.1\|742029_742572_+	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AVU06280.1\|742743_742839_+	hypothetical protein	NA	NA	NA	NA
AVU06281.1\|743014_743182_+	nitrogen fixation protein NifR	NA	NA	NA	NA
AVU06282.1\|743450_744368_-	lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
AVU06283.1\|744458_744560_+	hypothetical protein	NA	NA	NA	NA
AVU06284.1\|744637_746143_-	MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AVU06285.1\|746208_746454_-	hypothetical protein	NA	NA	NA	NA
AVU06286.1\|746483_746984_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AVU06287.1\|747003_747870_-	EamA family transporter	NA	NA	NA	NA
AVU06288.1\|748254_748521_+	ribonucleoside-diphosphate reductase	NA	NA	NA	NA
AVU06289.1\|748670_749069_+	protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AVU06290.1\|749031_751137_+	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AVU06291.1\|751254_752226_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AVU06292.1\|752406_752562_+	hypothetical protein	NA	NA	NA	NA
AVU08204.1\|752600_753572_+	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AVU06293.1\|753558_754515_+	iron ABC transporter permease	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AVU06294.1\|754511_755273_+	iron ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

928547 : 979342

Streptococcus_phage(33.33%)

protease,tRNA,bacteriocin,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU06464.1\|928547_929537_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AVU06465.1\|929830_930226_+	regulatory protein Spx	NA	NA	NA	NA
AVU06466.1\|930596_931316_+	adaptor protein MecA	NA	NA	NA	NA
AVU06467.1\|931436_932423_+	competence protein CoiA	NA	NA	NA	NA
AVU06468.1\|932470_934279_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
AVU06469.1\|934738_935545_-	hypothetical protein	NA	NA	NA	NA
AVU06470.1\|935567_935933_-	globin	NA	NA	NA	NA
AVU06471.1\|936036_936630_-	adenylate cyclase	NA	NA	NA	NA
AVU06472.1\|936815_937163_+	hypothetical protein	NA	NA	NA	NA
AVU06473.1\|937179_937815_+	GTP pyrophosphokinase	NA	NA	NA	NA
AVU06474.1\|937831_938641_+	NAD(+) kinase	NA	NA	NA	NA
AVU06475.1\|938637_939492_+	RNA pseudouridine synthase	NA	NA	NA	NA
AVU06476.1\|939512_940898_+	magnesium transporter	NA	NA	NA	NA
AVU06477.1\|940907_942752_+	sodium:proton antiporter	NA	NA	NA	NA
AVU06478.1\|943029_943800_+	enoyl-ACP reductase	NA	NA	NA	NA
AVU06479.1\|943996_945082_-	AI-2E family transporter	NA	NA	NA	NA
AVU06480.1\|947136_947895_+	acetylesterase	NA	NA	NA	NA
AVU06481.1\|948088_948598_+	hypothetical protein	NA	NA	NA	NA
AVU06482.1\|948710_949919_-	MFS transporter	NA	NA	NA	NA
AVU06483.1\|949878_951054_-	diacylglycerol beta-glucosyltransferase	NA	NA	NA	NA
AVU06484.1\|951486_952971_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
AVU06485.1\|952951_953212_+	hypothetical protein	NA	NA	NA	NA
AVU06486.1\|953211_954774_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
AVU06487.1\|955075_955879_+	hypothetical protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
AVU06488.1\|956097_958422_+\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
AVU06489.1\|958438_959797_+	Ktr system potassium uptake protein D	NA	NA	NA	NA
AVU06490.1\|959935_961447_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
AVU06491.1\|961933_962503_-	competence protein ComK	NA	NA	NA	NA
AVU06492.1\|962712_962931_+	IDEAL domain protein	NA	NA	NA	NA
AVU06493.1\|963011_963998_-	lipoate--protein ligase	NA	NA	NA	NA
AVU06494.1\|964196_964373_+	DUF2187 domain-containing protein	NA	NA	NA	NA
AVU06495.1\|964387_964990_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AVU06496.1\|965259_965367_+\|holin	putative holin-like toxin	NA	NA	NA	NA
AVU06497.1\|965905_966007_+	hypothetical protein	NA	NA	NA	NA
AVU08208.1\|966016_966289_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
AVU06498.1\|966332_968297_+	hypothetical protein	NA	NA	NA	NA
AVU06499.1\|968299_968620_+	hypothetical protein	NA	NA	NA	NA
AVU06500.1\|968616_969258_+\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
AVU06501.1\|969345_969636_-	hypothetical protein	NA	NA	NA	NA
AVU06502.1\|969776_969914_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
AVU06503.1\|970002_970359_-	hypothetical protein	NA	NA	NA	NA
AVU06504.1\|970846_971806_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AVU06505.1\|971851_971983_-	hypothetical protein	NA	NA	NA	NA
AVU06506.1\|972046_972337_-	hypothetical protein	A0A060AN66	Enterococcus_phage	7.5e-07	38.0
AVU06507.1\|972426_972978_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVU06508.1\|973029_973968_-	1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA	NA	NA	NA
AVU06509.1\|974118_974223_+	hypothetical protein	NA	NA	NA	NA
AVU06510.1\|974299_975511_+	isochorismate synthase	NA	NA	NA	NA
AVU06511.1\|975497_977171_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase	NA	NA	NA	NA
AVU06512.1\|977157_977961_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
AVU06513.1\|977953_978775_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AVU06514.1\|979012_979342_-\|protease	cysteine protease	NA	NA	NA	NA

DBSCAN-SWA_4

1000616 : 1009071

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU08210.1\|1000616_1001081_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.5e-20	43.8
AVU06532.1\|1001067_1002192_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AVU06533.1\|1002195_1002900_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	6.2e-47	41.6
AVU06534.1\|1002899_1003163_+	phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
AVU06535.1\|1003164_1003836_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AVU06536.1\|1003828_1006018_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	7.9e-141	39.7
AVU06537.1\|1005996_1007481_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
AVU06538.1\|1007473_1008502_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
AVU06539.1\|1008504_1009071_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_5

1623679 : 1632722

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU07103.1\|1623679_1624198_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AVU07104.1\|1624219_1626493_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
AVU07105.1\|1626695_1628975_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AVU07106.1\|1629249_1629510_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AVU07107.1\|1629528_1630668_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AVU07108.1\|1630690_1631716_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AVU07109.1\|1631717_1632722_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_6

1757802 : 1819625

Staphylococcus_phage(95.56%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU07223.1\|1757802_1764363_-	peptidase	A0A2H4PQU6	Staphylococcus_phage	1.4e-305	98.2
AVU07224.1\|1764688_1765000_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
AVU07225.1\|1765021_1767436_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
AVU07226.1\|1767726_1768908_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
AVU07227.1\|1769017_1769971_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AVU07228.1\|1769967_1770531_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AVU07229.1\|1770653_1771055_-	MarR family transcriptional regulator	NA	NA	NA	NA
AVU07230.1\|1771626_1772454_-	lysophospholipase	NA	NA	NA	NA
AVU07231.1\|1772456_1772576_-	hypothetical protein	NA	NA	NA	NA
AVU07232.1\|1772687_1773689_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
AVU07233.1\|1773810_1774275_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
AVU07234.1\|1774287_1775469_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
AVU07235.1\|1775479_1776112_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
AVU08236.1\|1776118_1777150_-	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
AVU07236.1\|1777642_1779145_-	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
AVU07237.1\|1779667_1779982_+	transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
AVU07238.1\|1779981_1781274_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AVU07239.1\|1781360_1782215_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AVU07240.1\|1782490_1782715_-	hypothetical protein	NA	NA	NA	NA
AVU07241.1\|1782913_1783384_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	8.8e-82	98.1
AVU07242.1\|1783496_1783940_+	competence protein ComK	NA	NA	NA	NA
AVU07243.1\|1783926_1784370_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AVU07244.1\|1784665_1785301_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AVU07245.1\|1785740_1786454_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AVU07246.1\|1786713_1787016_+	hypothetical protein	NA	NA	NA	NA
AVU07247.1\|1787271_1787637_+	camphor resistance protein CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AVU07248.1\|1787633_1787987_+	camphor resistance protein CrcB	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
AVU07249.1\|1789983_1790817_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.3e-157	98.9
AVU07250.1\|1791028_1791937_-	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
AVU07251.1\|1792058_1793255_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
AVU07252.1\|1793626_1795219_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AVU08237.1\|1795596_1796343_-	dipeptidyl aminopeptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
AVU07253.1\|1796347_1796821_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
AVU07254.1\|1796886_1797144_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AVU07255.1\|1797140_1798142_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.3e-185	97.3
AVU07256.1\|1798146_1799625_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	4.0e-282	97.4
AVU08238.1\|1799783_1800239_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
AVU07257.1\|1800542_1801193_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.9e-51	94.0
AVU07258.1\|1801273_1802269_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
AVU07259.1\|1802343_1802970_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
AVU07260.1\|1803010_1803352_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
AVU07261.1\|1803452_1804025_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
AVU07262.1\|1805597_1805699_+	hypothetical protein	NA	NA	NA	NA
AVU07263.1\|1806774_1808004_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	4.0e-134	64.7
AVU07264.1\|1807996_1809736_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
AVU07265.1\|1809716_1809851_-	hypothetical protein	NA	NA	NA	NA
AVU07266.1\|1810403_1811123_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
AVU07267.1\|1811243_1811963_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
AVU07268.1\|1812020_1812743_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
AVU07269.1\|1812867_1813575_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
AVU07270.1\|1814010_1814229_-	hypothetical protein	NA	NA	NA	NA
AVU07271.1\|1814537_1815119_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8
AVU07272.1\|1815591_1815810_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	2.0e-25	80.6
AVU07273.1\|1816065_1816539_+	hypothetical protein	NA	NA	NA	NA
AVU07274.1\|1816543_1817335_+	hypothetical protein	NA	NA	NA	NA
AVU07275.1\|1817704_1818688_-	leucotoxin LukDv	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
AVU07276.1\|1818689_1819625_-	gamma-hemolysin subunit A	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0

DBSCAN-SWA_7

1825825 : 1830072

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU07282.1\|1825825_1826581_-	exotoxin	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4
AVU07283.1\|1826619_1827015_-	enterotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-26	50.4
AVU07284.1\|1826989_1827391_-	enterotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-10	37.9
AVU07285.1\|1827544_1828273_-	exotoxin	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
AVU07286.1\|1828307_1829027_-	exotoxin	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
AVU07287.1\|1829307_1830072_-	exotoxin	A0A1X9H080	Staphylococcus_phage	2.3e-31	37.1

DBSCAN-SWA_8

1953604 : 2018119

Staphylococcus_phage(92.21%)

integrase,head,coat,holin,portal,capsid,tail,terminase

attL 1974353:1974370|attR 1999170:1999187

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU07404.1\|1953604_1953805_+	hypothetical protein	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0
AVU07405.1\|1954176_1954356_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
AVU07406.1\|1954670_1954931_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
AVU07407.1\|1954983_1955334_-	inhibitor	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
AVU07408.1\|1956016_1956466_+	chemotaxis inhibitory protein	A0A075LZI2	Staphylococcus_phage	8.7e-79	100.0
AVU07409.1\|1957541_1958033_-	staphylokinase	A0A075LYD3	Staphylococcus_phage	8.0e-86	100.0
AVU07410.1\|1958227_1958983_-	amidase	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AVU07411.1\|1958994_1959249_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AVU07412.1\|1959300_1959408_+	hypothetical protein	NA	NA	NA	NA
AVU08241.1\|1959460_1959637_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
AVU07413.1\|1959839_1960622_-	exotoxin	A0A075M4C7	Staphylococcus_phage	1.6e-149	99.6
AVU07414.1\|1961033_1961408_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
AVU07415.1\|1961463_1961751_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
AVU07416.1\|1961796_1961949_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
AVU07417.1\|1961941_1965721_-	hypothetical protein	A0A068A201	Staphylococcus_phage	0.0e+00	99.5
AVU07418.1\|1965736_1967221_-\|tail	phage tail protein	A0A2I6PDJ0	Staphylococcus_phage	4.5e-297	99.8
AVU07419.1\|1971991_1972342_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AVU07420.1\|1972391_1972616_-	hypothetical protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
AVU07421.1\|1972657_1973302_-\|tail	phage tail protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
AVU07422.1\|1973302_1973710_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.9e-71	99.3
AVU07423.1\|1973706_1974111_-	hypothetical protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
AVU07424.1\|1974107_1974470_-\|head,tail	phage head-tail adapter protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
1974353:1974370	attL	NA	NA	NA	NA
AVU07425.1\|1974453_1974738_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AVU07426.1\|1974727_1975012_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AVU07427.1\|1975031_1976177_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
AVU07428.1\|1976200_1976938_-	peptidase	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
AVU07429.1\|1976921_1978109_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AVU07430.1\|1978124_1979786_-\|terminase	terminase	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	99.8
AVU07431.1\|1979782_1980127_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AVU07432.1\|1980256_1980556_-	HNH endonuclease	A0A2I6PDH9	Staphylococcus_phage	3.5e-52	100.0
AVU07433.1\|1980787_1981204_-	transcriptional regulator	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AVU07434.1\|1981231_1981432_-	hypothetical protein	D2JLD9	Staphylococcus_phage	5.3e-28	98.5
AVU07435.1\|1981431_1981581_-	transcriptional regulator	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AVU07436.1\|1981577_1981784_-	DUF1381 domain-containing protein	A0A2I6PEA2	Staphylococcus_phage	1.1e-17	94.1
AVU07437.1\|1981780_1982026_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	2.5e-35	98.8
AVU07438.1\|1982062_1982599_-	dUTPase	Q9MBR0	Staphylococcus_prophage	1.6e-95	100.0
AVU07439.1\|1982595_1982841_-	hypothetical protein	Q8SDV5	Staphylococcus_phage	1.7e-36	95.1
AVU07440.1\|1982855_1983104_-	hypothetical protein	A0A0K1LL46	Staphylococcus_phage	7.5e-40	96.3
AVU07441.1\|1983100_1983358_-	hypothetical protein	A0A1X9H067	Staphylococcus_phage	6.3e-42	98.8
AVU07442.1\|1983357_1983729_-	hypothetical protein	A0A2I6PDG3	Staphylococcus_phage	1.4e-50	91.1
AVU07443.1\|1983741_1984146_-	hypothetical protein	A0A075M042	Staphylococcus_phage	8.4e-73	100.0
AVU07444.1\|1984154_1984373_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
AVU07445.1\|1984379_1985273_-	DNA replication protein DnaD	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
AVU07446.1\|1985302_1985773_-	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	5.7e-81	100.0
AVU07447.1\|1985773_1986406_-	MBL fold metallo-hydrolase	A0A1P8L6F7	Staphylococcus_phage	1.2e-86	100.0
AVU07448.1\|1986471_1987392_-	recombinase	A0A1P8L6F6	Staphylococcus_phage	5.1e-166	100.0
AVU07449.1\|1987393_1989337_-	ATPase	A0A1P8L6F1	Staphylococcus_phage	0.0e+00	100.0
AVU07450.1\|1989345_1989609_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AVU07451.1\|1989617_1989878_-	hypothetical protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
AVU07452.1\|1989882_1990185_-	hypothetical protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
AVU07453.1\|1990278_1990440_-	DUF1270 domain-containing protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
AVU07454.1\|1990436_1990760_-	hypothetical protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
AVU07455.1\|1990814_1991195_+	hypothetical protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
AVU07456.1\|1991181_1991379_-	hypothetical protein	O80075	Staphylococcus_phage	2.5e-30	100.0
AVU07457.1\|1991394_1992147_-	oxidoreductase	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
AVU07458.1\|1992197_1992527_+	hypothetical protein	M9NS98	Staphylococcus_phage	5.1e-52	98.2
AVU07459.1\|1992515_1992731_-	hypothetical protein	A0A0H3U4C7	Staphylococcus_phage	4.8e-35	100.0
AVU07460.1\|1993143_1993857_+	transcriptional regulator	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
AVU07461.1\|1993872_1994805_+	ATP-dependent helicase	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
AVU07462.1\|1994810_1995152_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
AVU07463.1\|1995355_1995538_+	hypothetical protein	A0A2I6PDF8	Staphylococcus_phage	6.9e-27	100.0
AVU07464.1\|1995637_1996621_+	glycosyl transferase family A	NA	NA	NA	NA
AVU07465.1\|1996631_1996874_+	hypothetical protein	NA	NA	NA	NA
AVU07466.1\|1996936_1997974_+\|integrase	site-specific integrase	Q38086	Staphylococcus_phage	1.4e-175	98.6
AVU07467.1\|1998030_1998855_+	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	6.8e-162	100.0
AVU07468.1\|1999092_2000109_-	gamma-hemolysin subunit B	A0A1X9IGW5	Staphylococcus_phage	6.7e-26	30.2
1999170:1999187	attR	NA	NA	NA	NA
AVU07469.1\|2000130_2001186_-	succinyl-diaminopimelate desuccinylase	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
AVU07470.1\|2001621_2002845_+	succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
AVU07471.1\|2003288_2004596_+	potassium transporter KtrB	NA	NA	NA	NA
AVU07472.1\|2005592_2006315_+	exotoxin	A0A1X9H080	Staphylococcus_phage	1.2e-26	34.9
AVU07473.1\|2006483_2007284_-	enterotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	6.1e-51	47.5
AVU07474.1\|2008071_2008632_+	hypothetical protein	Q4ZBG8	Staphylococcus_virus	5.4e-62	68.1
AVU07475.1\|2009509_2010214_+	toxin	NA	NA	NA	NA
AVU07476.1\|2010368_2010938_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.2e-101	98.9
AVU07477.1\|2010934_2011276_-	pathogenicity island protein	A0A1W6JQM3	Staphylococcus_phage	3.2e-57	97.3
AVU07478.1\|2011278_2011806_-\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	1.7e-86	94.9
AVU07479.1\|2011856_2012075_-	hypothetical protein	NA	NA	NA	NA
AVU07480.1\|2012092_2012671_-	pathogenicity island protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
AVU07481.1\|2012682_2013024_-	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	1.6e-56	96.5
AVU07482.1\|2014111_2014357_-	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	7.7e-29	95.2
AVU07483.1\|2014340_2015210_-	mobile element-associated protein	A0A1W6JQL5	Staphylococcus_phage	2.7e-161	95.8
AVU08242.1\|2015297_2015597_-	pathogenicity island protein	A0A1W6JQH0	Staphylococcus_phage	1.9e-21	61.2
AVU07484.1\|2015742_2015889_-	pathogenicity island protein	NA	NA	NA	NA
AVU07485.1\|2016142_2017759_-	molecular chaperone GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
AVU07486.1\|2017834_2018119_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP021105

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection