CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP019797	Stenotrophomonas acidaminiphila strain SUNEO chromosome, complete genome	2 crisprs	DEDDh,DinG,WYL,cas3,csa3	0	8	0	0

1. CP019797

CRISPR-Cas detection and classification

Crispr_ID: CP019797_5

• CRISPR_ID: CP019797_5
• CRISPR_location: 2656125-2656264
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of CP019797_5

Consensus_repeat	Method
GCGCCGTTCAATCACAGGCAGGGGCTACGTCCTCCGCGCCCGCAT	CRISPRCasFinder

spacers of CP019797_5

>5.1|2656170|50|CP019797|CRISPRCasFinder
CCAGGGCATCGTGCGGGGCAAGCCCCGCACCTACGGAGAGCGTTGCCAAT

CRISPR arrays and Neighbor proteins around CP019797_5

CRISPR arrays

The CRISPR arrays of CP019797_5

>merge|CP019797|5|2656125-2656264|CRISPRCasFinder
GCGCCGTTCAATCACAGGCAGGGGCTACGTCCTCCGCGCCCGCATCCAGGGCATCGTGCGGGGCAAGCCCCGCACCTACGGAGAGCGTTGCCAATGCGCCGTTCAATCACAGGCAGGGGCTAGGTCCTCCGCGCCCGCAT

>CP019797|5|4|2656125-2656264|CRISPRCasFinder
GCGCCGTTCAATCACAGGCAGGGGCTACGTCCTCCGCGCCCGCAT	CCAGGGCATCGTGCGGGGCAAGCCCCGCACCTACGGAGAGCGTTGCCAAT
GCGCCGTTCAATCACAGGCAGGGGCTAGGTCCTCCGCGCCCGCAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP019797.1|AUZ55675.1|2657186_2658356_-|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
CP019797.1|AUZ55674.1|2656494_2657190_-|DnaA-regulatory-inactivator-Hda	unknown	unknown	gnl|CDD|181541
CP019797.1|AUZ55667.1|2643953_2647295_-|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|274362
CP019797.1|AUZ55664.1|2642740_2643100_+|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
CP019797.1|AUZ56575.1|2662483_2663227_+|hypothetical-protein	unknown	unknown	gnl|CDD|378635
CP019797.1|AUZ55672.1|2654327_2655341_+|aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|225719
CP019797.1|AUZ55665.1|2643096_2643330_+|hypothetical-protein	unknown	unknown	gnl|CDD|238089
CP019797.1|AUZ55681.1|2663988_2664864_-|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|180194
CP019797.1|AUZ55677.1|2660642_2661086_+|hypothetical-protein	unknown	unknown	unknown
CP019797.1|AUZ55678.1|2661129_2661738_+|hypothetical-protein	unknown	unknown	gnl|CDD|378345
CP019797.1|AUZ55669.1|2651873_2652206_-|competence-protein-ComEA	unknown	unknown	gnl|CDD|378965
CP019797.1|AUZ56574.1|2659559_2660618_+|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl|CDD|235439
CP019797.1|AUZ55670.1|2652406_2653900_+|peptidase-M20	unknown	unknown	gnl|CDD|349931
CP019797.1|AUZ55668.1|2647536_2649774_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
CP019797.1|AUZ55680.1|2663229_2663913_+|hypothetical-protein	unknown	unknown	gnl|CDD|378635
CP019797.1|AUZ55673.1|2655337_2656042_+|mannose-1-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|133044
CP019797.1|AUZ55676.1|2658352_2659513_-|hypothetical-protein	unknown	unknown	gnl|CDD|225788
CP019797.1|AUZ55671.1|2653964_2654234_+|hypothetical-protein	unknown	unknown	gnl|CDD|225170
CP019797.1|AUZ55666.1|2643577_2643934_+|alkylhydroperoxidase	unknown	unknown	gnl|CDD|223672
CP019797.1|AUZ55679.1|2661734_2662394_+|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl|CDD|235544

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP019797.1|AUZ55664.1|2642740_2643100_+|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	3.7e-22	73.6	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP019797.1|AUZ55675.1|2657186_2658356_-|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	9.80708e-65
CP019797.1|AUZ55674.1|2656494_2657190_-|DnaA-regulatory-inactivator-Hda	gnl|CDD|181541	PRK08727, PRK08727, DnaA regulatory inactivator Hda.	6.90041e-125
CP019797.1|AUZ55667.1|2643953_2647295_-|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.6131e-46
CP019797.1|AUZ55664.1|2642740_2643100_+|transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	5.97983e-21
CP019797.1|AUZ56575.1|2662483_2663227_+|hypothetical-protein	gnl|CDD|378635	pfam11306, DUF3108, Protein of unknown function (DUF3108). This is a bacterial family of putative lipoproteins. Structure 3fzx, the first structural template for this large family including several homologs in the human gut microbiome and in metagenomic datasets, folds into a beta barrel that topologically looks like a small-scale porin (such as FepA). Bacteroides fragilis glyA is a putative exported protein, and this fold is of the YmcC-like type, with a predicted signal peptide SpI cleavage site AGAMA|QNQDC, and a Phobius server prediction of non-cytoplasmic localization for amino acids 21-236. The possibility of it being a membrane protein can be ruled out by the hydrophilic nature of the solvent exposed surface outside the barrels. Analysis of sequence conservation suggests that an area near Glu172/Trp206 is potentially interesting. These two residues are also conserved in Dali hit Structure 2in5, a hypothetical lipoprotein classified as a new YmcC-like fold in SCOP (SCOP:159271, with a 12-stranded meander beta-sheet folded into a deformed beta-barrel) despite large structural differences between the two structures, suggesting similarity in function.	2.11155e-14
CP019797.1|AUZ55672.1|2654327_2655341_+|aminoglycoside-phosphotransferase	gnl|CDD|225719	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only].	3.87255e-101
CP019797.1|AUZ55665.1|2643096_2643330_+|hypothetical-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.17869e-10
CP019797.1|AUZ55681.1|2663988_2664864_-|succinate--CoA-ligase-subunit-alpha	gnl|CDD|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
CP019797.1|AUZ55678.1|2661129_2661738_+|hypothetical-protein	gnl|CDD|378345	pfam09997, DUF2238, Predicted membrane protein (DUF2238). This domain, found in various hypothetical bacterial proteins, has no known function.	6.309e-49
CP019797.1|AUZ55669.1|2651873_2652206_-|competence-protein-ComEA	gnl|CDD|378965	pfam12836, HHH_3, Helix-hairpin-helix motif. The HhH domain is a short DNA-binding domain.	3.78508e-21
CP019797.1|AUZ56574.1|2659559_2660618_+|phosphoribosylformylglycinamidine-cyclo-ligase	gnl|CDD|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
CP019797.1|AUZ55670.1|2652406_2653900_+|peptidase-M20	gnl|CDD|349931	cd05682, M20_dipept_dapE, uncharacterized M20 dipeptidase. Peptidase M20 family, unknown dipeptidase-like subfamily (inferred by homology to be dipeptidases). M20 dipeptidases include a large variety of bacterial enzymes including cytosolic nonspecific dipeptidase (CNDP), Xaa-methyl-His dipeptidase (anserinase),and canosinase. These dipeptidases have been shown to act on a wide range of dipeptides, but not larger peptides. For example, anserinase mainly catalyzes the hydrolysis of N-alpha-acetylhistidine while carnosinase degrades beta-alanyl-L-histidine. This family includes dapE (Lpg0809) from Legionella pneumophila.	0
CP019797.1|AUZ55668.1|2647536_2649774_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.48004e-54
CP019797.1|AUZ55680.1|2663229_2663913_+|hypothetical-protein	gnl|CDD|378635	pfam11306, DUF3108, Protein of unknown function (DUF3108). This is a bacterial family of putative lipoproteins. Structure 3fzx, the first structural template for this large family including several homologs in the human gut microbiome and in metagenomic datasets, folds into a beta barrel that topologically looks like a small-scale porin (such as FepA). Bacteroides fragilis glyA is a putative exported protein, and this fold is of the YmcC-like type, with a predicted signal peptide SpI cleavage site AGAMA|QNQDC, and a Phobius server prediction of non-cytoplasmic localization for amino acids 21-236. The possibility of it being a membrane protein can be ruled out by the hydrophilic nature of the solvent exposed surface outside the barrels. Analysis of sequence conservation suggests that an area near Glu172/Trp206 is potentially interesting. These two residues are also conserved in Dali hit Structure 2in5, a hypothetical lipoprotein classified as a new YmcC-like fold in SCOP (SCOP:159271, with a 12-stranded meander beta-sheet folded into a deformed beta-barrel) despite large structural differences between the two structures, suggesting similarity in function.	8.20384e-18
CP019797.1|AUZ55673.1|2655337_2656042_+|mannose-1-phosphate-guanylyltransferase	gnl|CDD|133044	cd06422, NTP_transferase_like_1, NTP_transferase_like_1 is a member of the nucleotidyl transferase family. This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.	1.24979e-85
CP019797.1|AUZ55676.1|2658352_2659513_-|hypothetical-protein	gnl|CDD|225788	COG3249, COG3249, Uncharacterized protein conserved in bacteria [Function unknown].	3.16188e-70
CP019797.1|AUZ55671.1|2653964_2654234_+|hypothetical-protein	gnl|CDD|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	5.12245e-10
CP019797.1|AUZ55666.1|2643577_2643934_+|alkylhydroperoxidase	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	3.72554e-20
CP019797.1|AUZ55679.1|2661734_2662394_+|phosphoribosylglycinamide-formyltransferase	gnl|CDD|235544	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed.	4.56e-99

Protein sequences

>CP019797.1|AUZ55673.1|2655337_2656042_+|mannose-1-phosphate-guanylyltransferase
MKALVFAAGLGERMRPLTEHTPKPLLPAGGKPLIAWHLEKLAALGVRDVVINTSWLAEQFPRALGDGSRWNLRLHYAHEGPTPLETGGGMLNALPLLGEAPFLVVNGDIWTDFDFSRLPREPAGEAHLLLVDNPPQHPRGDYHLDAHGVLHDDRDAPCLTYAGIGVYRPSILQGWRAVIGDAPGSERTPPRFSVVPLQKHFMAQGRMTGQHYRGRWTDVGTPQRLQALEETLSS
>CP019797.1|AUZ55672.1|2654327_2655341_+|aminoglycoside-phosphotransferase
MNPDISLEPQRARHRLEWARERLADATASIERASVDAGFRSYWRVTGDAGSHIVMDAPPGLEDPRPWLRMRELLLAHGLRVPALLAQDLDAGFLLLEDLGAPTLARLLDDGNADAWFDRAMEQLVRLQSIPVPDGFGEFGEALLQRDAGLFDEWFLQRHLGLQLDCGEVEGLQLVQRRLMDNALGQPQVMTHRDFMPRNLMPVADGPAVLDFQDMVRGPIAYDPVSLFKDAFLSWPLPRVDDWLARYHACALGAGLPVPDRATFLRDADWMGVQRHLKILGIFSRLHYRDGKSHYLEDVPRFIAYLDEVLPRHPQLSALQSLLQRRIKPALAARATR
>CP019797.1|AUZ55671.1|2653964_2654234_+|hypothetical-protein
MSGLFGSDSWLYIILVGFVVGLLGRFFMPGNNRMGCLLTIVLGIAGAVFAGWFGREMGWYAAGQPAGFVGAIIGAIALLALLRLVSGKR
>CP019797.1|AUZ55670.1|2652406_2653900_+|peptidase-M20
MDSAKLGQFLSDKWDSDIVPQLVDYIRIPNKSPMFDANWVANGYMDQAVALMEGWARAQKIPGLQVEVVRLEGRTPLIFLEIPASGPETGDDTVLLYGHLDKQPEMTGWDADLGPWKPVLRGDKLYGRGGADDGYALFGSLAAVLALQEQGLPHARCVILIEACEESGSYDLPAYVDHLAGRIGQPSLVVCLDSGCANYDQLWCTTSLRGLTGGNFTVKVLNEGVHSGDASGVVPSSFRLLRQLLSRIEDENTGRILLDGLHTEIPAERLEQARRAAEVVDTAIFDKFPLVDGLKPMNEDLTELVLNRTWRPALSVTGIGGMPPLESAGNVLRPETSVKLSLRLPPTANGKACGELLKEALLRDPPNGAHVSLELEKASTGWNAPAMAPWLEKSIDDASQAFFGKPAMYMGEGGSIPFMGMLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVSKVLFDHHAASLRGETSGSPVAADSGTRHGGHGCC
>CP019797.1|AUZ55669.1|2651873_2652206_-|competence-protein-ComEA
MKRFTVMLKSLVLALLLTASAHATDKVDINTATAAELDQVLVNVGAAKAQAIVEYRQANGPFKSVEELALVKGIGLKTVERNRDLIGVGAGTASAARPAKPAAAKPVERR
>CP019797.1|AUZ55668.1|2647536_2649774_-|TonB-dependent-receptor
MKRKYLSMAVGCALLAPAAFVQAQQQQPAAGQQATQLDEVTVTARRRAESIQDVPVAVSAFGEEQIKDLQASTVEGLQGAVPNMNIAQGRGSANSVNVFIRGIGQPDALQTFDPGVGMYVDDVYYSRINGALFSLFDIQQLEVLRGPQGTLYGKNSTGGAIKLTTKNPFDNEGGAVEVTAGDYGRLEGRFYVSGKLSDTIAASIAGAKITNDGYVKDAETGKRYNDDDTEALRFKMAFNPTDSFRATLSLDTTKQDAALTLGRPMADLRQTSLAPAGVIVLQPGETGEWNRRALTSFKNGEGQYLKHSGASLAMDWDINAQWTLKSISSYRKLKTKSYIDIDASEYELGDVLVALDQDQKSQEFQLHYDNGSNLHATFGAYYMKENVPSYQEAYADDLFSFLGAKVPFLRTINDDLTTTSNAAFAHLNWEFVPSWTVAAGVRWTKDKKDYARSTSTFWGAPFTALNETVAFAANASWTAVTPSISLQKAFGDNLMGYVSANRGFKSGGFNGRANTRYDTQHAKFDPEYVWTYELGLKGSSADRRFRGSAAAFYSNYSDFQARVSQDVGTFPVLNAAKLNIKGIELEGSALLGEATTLSAQIGWMDAKYDKFEDFRLDPSYPGFDPNVSHDHVPFSPDWTARVALQHVFSLGDNGNLTFGGDVSYRGKTWLSVDNRAVLSQDAYTLLGVYGVWDSPQMAWQVRAGVRNLTDKEYKTEGQEFASVGNIQTAYYGLPRNWYMSLRYNF
>CP019797.1|AUZ55667.1|2643953_2647295_-|hybrid-sensor-histidine-kinase/response-regulator
MLSLVTVALAGVAWLVLMFGVALYGERRPTVFARHWRHVYALSLAVHCTSWTFYGTVTQAARYGWPLPPTFVGAILFYALGIGMMVRLVRLARETNATSLADLIAARLGRDAWLAATVTLIAALGLIPYIALQLKAVAMSFAMLTLRSADAVDAAPWRDSALYVALAMALFAMLFGARRADVSEHNRGLVLAMAAESLFKLGAMLALGAFVWFGLDAVAVPPPAPVADAPAGGFMPLVLLGALAMFLLPHQFHVGVVECRDPADIRTSRWLFPLYLLLIALPILPLARAGTALLGDSVPSDMYTLALPFSAGHTGVALFAFLGGLSAATGMVVVSTLTLSLMIGNHWFAPGLLRSTWARAGGDHRRELVWLRRAGICVIMLLAWGYSRSIGGGNVLADIGAISFSAMATLVPVLGFAIWRPQTPPRAAIAGVLAGFATWAWVLLLPTLLESSGRVPAWLAHGPLGWRWLAPEALFGLTGWSPLGRAVGASLFVGTAVTLLVMAWRRDTPDRTRRNLDADALRDAGRRFLPWEKVQRLLADAPRQGPVPAATEASIERELSAVLGAASARLLLDAARRESGELATVAAIVSEASLDLRFNQQVLQAALQNMSQGISVIDREQRLVAWNRPYAQLFGFPDELLQVGRPIVDLTRWALQALPQRGSDERAVDRRLAFMRAGTAHLTERVFPDGRIVEIRGNPMPGGGFVATFTDVTEFRRTEQELMRSNETLEQRVGERTALLESAKREAERANDAKSRFLAAIGHDLLQPLHAAHLFTDTLAQQVEAPSQRQAVAQIRGALDSTTQLLTGLFDMSRLEAGGLVPQPRGMPLAEVLDPLASEFRALAAARGLGFRYVPTRAWVNSDPQLLRRVLQNFLANAVRYTARGGVLLGVRREGGRLRIEVHDTGPGIAATEQRRIFEEFRRGEDSGGQGLGLGLAIADRIAGLLQAPLRLRSTLGRGTVFSVAVDALPVSTPAAPPPGPAEPAARGAVRVLVVDNDPAALAGLAALLRGWGYDVAEASAEAAAVAAMQAAPAALWLFDYNLDDGDTGTALQARLGARFGTRPTLILSADDSLATRREVLEQGLTLLHKPVRPLALKSIMDRLLAARALARP
>CP019797.1|AUZ55666.1|2643577_2643934_+|alkylhydroperoxidase
MSATPSYTELTRDISRNLTPLRTHNADVMQGFGALSKAAMAAGALDEKTKELIAMAIGVANRCDGCLGFHAKALVRLGATPEEFREMLGVAVYMGGGPSLMYAANALAAFEEFSTAQG
>CP019797.1|AUZ55665.1|2643096_2643330_+|hypothetical-protein
MITLLRPLFGRRGGQLTAHEARARMQRGAVLVDVREAAEFARGHAPGARLLPLSRIRAGAAGALESLDLPGAPANCC
>CP019797.1|AUZ55664.1|2642740_2643100_+|transcriptional-regulator
MMMADTASRPPFDVTAMRAHAGDAAQLLKALANENRLQVLCLLAEGERSVGEINALLDLSQSALSQHLAVLREEGLVLTRREAQTIVYALADGPAAAVMHTLHGIYCGRPATRGKAGKP
>CP019797.1|AUZ55674.1|2656494_2657190_-|DnaA-regulatory-inactivator-Hda
MSVPQLPLALRYPPDQRLETFIGAPDGALAQLRAAATGDSRDWVYLVGPAGSGKTHLALAVCAAAEQAGRGSAYLPLQAAAGRLRDALEALEGRDVVALDGLDAIAGQREDEVALFDFHNRARAAGVTLLYTASAAPDALGLVLPDLRSRLSQCGRILLDALDDAGRGAVLRERAIRRGLALDQAAIDWLLTRTGRDLGGLVVLLDRLDRESLAAKRRITVPFLRQVLDGS
>CP019797.1|AUZ55675.1|2657186_2658356_-|AI-2E-family-transporter
MNSSADTEIALFLRRVKWAVLGAFAMWVLWLLAPILTPFVVALMLAWLGDPLVDRLEARGRSRNTAVILVFALMILLLALALLILVPMIQRQITTLVAALPQAQEWLMGTALPWIERRTGVEILGWLEPERLFEWIRTHWQQAGGAASTLFGYLSRSGFAMVAWVVNLALLPILAYYFLRDWDRLVERVASVIPRNHIETVSRLARESNDVLGAFIRGQIAVMIALGVVYAVGLSVVGLNLGLLIGLVAGLISFIPYLGATTGVVLAVLAALVQAQGFDLKLLALVGVVFTVGQLLESYVLTPRIVGDKIGLHPVAVIFAVMAGGQLFGFLGMLLALPAAAVINVLLRYAHERYRQSELYAGHGPTIVLQSSGEPAPGMGIVPKDVEQK
>CP019797.1|AUZ55676.1|2658352_2659513_-|hypothetical-protein
MAPRPHSGNNSHRNRRAMEPSMRRSLAFFLFMALCLSVPAALAQSGLRTEGDIASAQNAYEAEVPVNSQGDADRNGALARALGAVLGKLSGDRSAMTRPGVAQALRSARDMVESYDYRQDQSVSASGAPSFRTMLVARFRQDDVDGLVAALGLPVWPQPRPKPVVWMAIDDGSGPRLVSVQQANAARPLLDRAIERGFRLGLPGGGAAEQALVGAIWRQDTAAIARASARYAPPMQLVGKLYRASGGGWMADWVFVDDGRELARWSTRDGDARRAMAGGADGAADALVKRYAKAPVTGAAGTYRIRVSGLRTAADYLRVAATLQSVPVVRSVVPVQASGDRLELDLELMSGLQGLNRMLGADAALQPVAPPAEGAPASTTAEYRVR
>CP019797.1|AUZ56574.1|2659559_2660618_+|phosphoribosylformylglycinamidine-cyclo-ligase
MTSSPTSANSPLTYRDAGVDIDAGNELVERIKPLVKRSFRPEVMGGLGGFGALFDLSGKYREPVLVSGTDGVGTKLKLAQQLGRHDTIGIDLVAMCVNDVLVQGAEPLFFLDYFATGKLDIDTAAAVVGGIANGCTEAGCALIGGETAEMPDMYAPGEYDLAGFTVAAVEKSELKDGSSVRQGDVLIGIASSGPHSNGYSLVRRIYDRAGQPADLVLEDGVKLVDALMAPTRLYVKPILSLLKEHGAAIHGMAHITGGGLTENIIRVVPDGLGLDIDAGSWTLPPVFQWLQREGNVADSEMWRTFNCGIGFVLLVPADQAAAIGASLDTLQLAHWQIGQVVAAEGGERVRIG
>CP019797.1|AUZ55677.1|2660642_2661086_+|hypothetical-protein
MDPVTAPAPPPRLTDEDASQLRLLSIFHYVVAAITGLFSLIPVLHLVMGLAMATGRLPVETGTSGAQAIDPRLFGWFFVAFAGVFIACGLALAGFMAHAGRCLRQRRRYTLCLVVAAISCMMMPFGTVLGVFTLIVLMRPSVKAAFA
>CP019797.1|AUZ55678.1|2661129_2661738_+|hypothetical-protein
MSPAKKAAFAGVLAVFLLTWIKPLWPLEQALHSSLTVVGLAALWWVDRRWPLDGGAFAAICGFVALHCIGARWLYSNVPYETWLQALAGWSPGAAFGWQRNHFDRLIHLLYGACFTPALAQLARHAWPALRGGQAFVLAVMAVMCSSLVYEWLEWGIALALSPEAAEAYNGQQGDVWDAHADMLLATVGSLLAWPLARRVAR
>CP019797.1|AUZ55679.1|2661734_2662394_+|phosphoribosylglycinamide-formyltransferase
MSAPARIAVLASGRGSNLQCLLDGIGSGQLHARIAGVFSDKPGAAALDKVAPALRWARSPREFAGRDAFDAALGDAVAASTPDWIVCAGYMRILGAGFVQRFGGRLVNIHPSLLPRHKGLHTHARALEAGDAEHGASVHFVVPELDAGAVIAQARVPVLAGDDADALAARVLAVEHPLLLATVRLLVDGRVAEQDGTVLFDGQSLFNPLRLDSDGTLRR
>CP019797.1|AUZ56575.1|2662483_2663227_+|hypothetical-protein
MLASLLTTLPVMAQETAPATAAALPPAEWDPPALEPFVATYQAFYKGKEAGDATMRVVHDDGARWRVDMAVRGRRGFAGVLGLNLEQSTVFDNQGTVYVPLSQSTVKKALFLGKKVTGTYDWRDGTAQWHGDLKKERQRPIPLQPGDQSALLLNLSLMRDARPGQPLRYRYVDVGRVRQYEYQAATSTETVQVGDLSYDALRVYRTNGGNDETILWIANGVPTPVRILQREDGEDAIDLRLTEYQGA
>CP019797.1|AUZ55680.1|2663229_2663913_+|hypothetical-protein
MKPSLRHLPLAAAALAALASTPALAMQPFTANYQASYMGLQANGVMTLAAESGGKWRYTLQVKNQLAELSQSTLFDEQNGRLRPLSSHDASVIPFKRRAVDARYDWGSSQATWSGDVKPERRGPVALQNGDMDGLLINLAIARDVAAGKPLNYRMVDDGRVKTLTYRVVGKENMTVDGKTVEATKVARVDGNKEQIAWIAPGMPVPVRLLQREGGRDALDLTIKSLR
>CP019797.1|AUZ55681.1|2663988_2664864_-|succinate--CoA-ligase-subunit-alpha
MSVLINKNTKVIVQGFTGQQGTFHATQMIEYGTQVVGGVTPGKGGTTHIDLPVFNTVADAVASTGADASVIYVPPPFAADAILEAAAAGIKVIVCITEGIPVLDMLRVKNVLTRTYPETVLIGPNCPGVITPGECKIGIMPGHIHKPGKIGIVSRSGTLTYEAVKQTTEVGLGQSTCIGIGGDPINGLNFVDCLKLFNEDPQTEGIIMVGEIGGDAEEAGAEYIKAHVKKPVVGFIAGASAPAGKRMGHAGAIASGGKGTAEGKFAAMEAAGVVTVRSPGDLGAAIAKLVK

Crispr_ID: CP019797_6

• CRISPR_ID: CP019797_6
• CRISPR_location: 2766375-2766493
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP019797_6

Consensus_repeat	Method
CGCTCCTGGCGGTTTTTGGTTCCCACCCTCCATGGCGGGAACCCT	CRISPRCasFinder

spacers of CP019797_6

>6.1|2766420|29|CP019797|CRISPRCasFinder
GCGGGCCATCGACAAGCGATGTCAAAAAC

CRISPR arrays and Neighbor proteins around CP019797_6

CRISPR arrays

The CRISPR arrays of CP019797_6

>merge|CP019797|6|2766375-2766493|CRISPRCasFinder
CGCTCCTGGCGGTTTTTGGTTCCCACCCTCCATGGCGGGAACCCTGCGGGCCATCGACAAGCGATGTCAAAAACCGCTCCTGGCGGCTTTTGGTTCCCACCCTCCATGGCGGGAACCCT

>CP019797|6|5|2766375-2766493|CRISPRCasFinder
CGCTCCTGGCGGTTTTTGGTTCCCACCCTCCATGGCGGGAACCCT	GCGGGCCATCGACAAGCGATGTCAAAAAC
CGCTCCTGGCGGCTTTTGGTTCCCACCCTCCATGGCGGGAACCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP019797.1|AUZ55747.1|2766815_2768090_-|citrate-(Si)-synthase	unknown	unknown	gnl|CDD|180164
CP019797.1|AUZ55743.1|2760390_2761068_-|fimbrial-protein	unknown	unknown	gnl|CDD|225708
CP019797.1|AUZ56586.1|2755825_2756743_-|ATPase	unknown	unknown	gnl|CDD|376643
CP019797.1|AUZ55745.1|2763054_2765478_+|peptidase	unknown	unknown	gnl|CDD|227342
CP019797.1|AUZ55741.1|2757943_2759833_-|fimbrial-protein	unknown	unknown	gnl|CDD|274173
CP019797.1|AUZ55750.1|2769787_2771932_-|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl|CDD|236794
CP019797.1|AUZ55752.1|2772891_2775051_-|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis(diphosphate)-3'-diphosphatase	unknown	unknown	gnl|CDD|223394
CP019797.1|AUZ56587.1|2761777_2762836_-|pilus-assembly-protein-PilM	unknown	unknown	gnl|CDD|378558
CP019797.1|AUZ55739.1|2754378_2755374_-|hypothetical-protein	unknown	unknown	gnl|CDD|238744
CP019797.1|AUZ55742.1|2759854_2760391_-|fimbrial-protein	unknown	unknown	gnl|CDD|377322
CP019797.1|AUZ56588.1|2776510_2777605_-|hypothetical-protein	unknown	unknown	gnl|CDD|365903
CP019797.1|AUZ55754.1|2775794_2776406_-|guanylate-kinase	unknown	unknown	gnl|CDD|234719
CP019797.1|AUZ55755.1|2778042_2778903_-|YicC-family-protein	unknown	unknown	gnl|CDD|236993
CP019797.1|AUZ55749.1|2768780_2769722_-|nucleoside-hydrolase	unknown	unknown	gnl|CDD|239115
CP019797.1|AUZ55748.1|2768454_2768697_-|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|234969
CP019797.1|AUZ55744.1|2761064_2761778_-|fimbrial-protein	unknown	unknown	gnl|CDD|225707
CP019797.1|AUZ55740.1|2755373_2755829_-|hypothetical-protein	unknown	unknown	gnl|CDD|379552
CP019797.1|AUZ55751.1|2771941_2772325_-|reactive-intermediate/imine-deaminase	unknown	unknown	gnl|CDD|129116
CP019797.1|AUZ55753.1|2775307_2775607_-|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl|CDD|234744
CP019797.1|AUZ55746.1|2765556_2766195_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP019797.1|AUZ55747.1|2766815_2768090_-|citrate-(Si)-synthase	gnl|CDD|180164	PRK05614, gltA, citrate synthase.	0
CP019797.1|AUZ55742.1|2759854_2760391_-|fimbrial-protein	gnl|CDD|377322	pfam04351, PilP, Pilus assembly protein, PilP. The PilP family are periplasmic proteins involved in the biogenesis of type IV pili.	1.08435e-71
CP019797.1|AUZ56586.1|2755825_2756743_-|ATPase	gnl|CDD|376643	pfam01882, DUF58, Protein of unknown function DUF58. This family of prokaryotic proteins have no known function. Caldicellulosiruptor saccharolyticus PepX, a protein of unknown function in the family, has been misannotated as alpha-dextrin 6-glucanohydrolase.	5.3043e-21
CP019797.1|AUZ55745.1|2763054_2765478_+|peptidase	gnl|CDD|227342	COG5009, MrcA, Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane].	0
CP019797.1|AUZ55741.1|2757943_2759833_-|fimbrial-protein	gnl|CDD|274173	TIGR02515, Putative_DNA_transport_protein_HofQ, type IV pilus secretin (or competence protein) PilQ. A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures].	0
CP019797.1|AUZ55750.1|2769787_2771932_-|ATP-dependent-DNA-helicase-RecG	gnl|CDD|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
CP019797.1|AUZ55752.1|2772891_2775051_-|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis(diphosphate)-3'-diphosphatase	gnl|CDD|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
CP019797.1|AUZ56587.1|2761777_2762836_-|pilus-assembly-protein-PilM	gnl|CDD|378558	pfam11104, PilM_2, Type IV pilus assembly protein PilM;. The type IV pilus assembly protein PilM is required for competency and pilus biogenesis. It binds to PilN and ATP.	9.21755e-171
CP019797.1|AUZ55739.1|2754378_2755374_-|hypothetical-protein	gnl|CDD|238744	cd01467, vWA_BatA_type, VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup are bacterial in origin. They are typified by the presence of a MIDAS motif.	1.19075e-77
CP019797.1|AUZ55743.1|2760390_2761068_-|fimbrial-protein	gnl|CDD|225708	COG3167, PilO, Tfp pilus assembly protein PilO [Cell motility and secretion / Intracellular trafficking and secretion].	3.7458e-77
CP019797.1|AUZ56588.1|2776510_2777605_-|hypothetical-protein	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.75464e-39
CP019797.1|AUZ55754.1|2775794_2776406_-|guanylate-kinase	gnl|CDD|234719	PRK00300, gmk, guanylate kinase; Provisional.	5.89886e-121
CP019797.1|AUZ55749.1|2768780_2769722_-|nucleoside-hydrolase	gnl|CDD|239115	cd02649, nuc_hydro_CeIAG, nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains eukaryotic, bacterial and archeal proteins similar to the purine-preferring nucleoside hydrolase (IAG-NH) from C. elegans and the salivary purine nucleosidase from Aedes aegypti. C. elegans IAG-NH exhibits a high affinity for the substrate analogue p-nitrophenylriboside (p-NPR). .	8.04037e-121
CP019797.1|AUZ55748.1|2768454_2768697_-|50S-ribosomal-protein-L31	gnl|CDD|234969	PRK01678, rpmE2, type B 50S ribosomal protein L31.	1.24624e-50
CP019797.1|AUZ55744.1|2761064_2761778_-|fimbrial-protein	gnl|CDD|225707	COG3166, PilN, Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion].	1.32755e-55
CP019797.1|AUZ55740.1|2755373_2755829_-|hypothetical-protein	gnl|CDD|379552	pfam14316, DUF4381, Domain of unknown function (DUF4381). This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 158 and 180 amino acids in length.	3.48894e-25
CP019797.1|AUZ55751.1|2771941_2772325_-|reactive-intermediate/imine-deaminase	gnl|CDD|129116	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase. This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other].	3.30744e-58
CP019797.1|AUZ55753.1|2775307_2775607_-|DNA-directed-RNA-polymerase-subunit-omega	gnl|CDD|234744	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed.	1.57553e-21
CP019797.1|AUZ55755.1|2778042_2778903_-|YicC-family-protein	gnl|CDD|236993	PRK11820, PRK11820, YicC family protein.	1.00078e-124

Protein sequences

>CP019797.1|AUZ55746.1|2765556_2766195_+|hypothetical-protein
MPRPAPNAQRGSRERQLIAQEAARLVRESGIHDLDQARRKAASRLGIHDEALWPRQAQVEEVLREQQRLFDAHAQPTALRQRRESAVQAMQFLQAFQPRLGGAVLAGTANASTPVVLHLHCDDPDAVQRFLHDQRIPAEARTSLLQLAGHTSRQPYPRWEFAADGIAFELIVLPEDALRHPPVSSDDGKPLPRATLAQLRQLLAGAQGQSAP
>CP019797.1|AUZ55745.1|2763054_2765478_+|peptidase
MPRFRRWLRWLLALCVALALVGAIAAGALYYVVSSKLPDVQALREVELQEPMYVHASDGKLMAVFGETRRYPVEMKDVPERLKQAFLATEDARFYEHGGVDYKGIARAVWLLATTSDRRVPGGSTITQQVARQFFLSSEYSYTRKLAEILLARRIESELSKDEIFELYLNKSFFGNRAYGIGAAAEYYYGKKLGELDLDEMASLAGIPKFPSSGNPISNPERARQRRDNYVLQRMADLGFISQAEADAAKAVPMHASPHEPPIEVNAPYVAEMVRQEMIALHGGDVLNKGYRVTTTIDSQAQEAANIAVRDGLLLYDHRHGWRGPEQHFDVAAEADAAALARHLAAIPAQSGLLPAIVSAVHADGGISVVLADRTELVLPVAASRWTTRAPAKLAARGDVIRVRAGDKEGEWLIEQLPLGQAALVSLDAGNGALRALVGGFSFAGNKFNRATQARRQPGSSFKPFLYAAAFDKGFNPASIVLDAPVVFRDRRGKTWEPKNDGGGFRGPMRLREALVQSRNLVSVRLLDSIGVDFARKYISEFGFQEAELPPNLSMSLGTASLTPLSVARGYAVFANGGSRVDTWTIDEVKDRDGNVVFKANPALACRGCGGAAGGTAPASQVVDGFNFGAEAAPVPASADAGTGTQAEPVAPNPDARTAPRAIDERTAYQLVSMMRDVVQRGTGTAAKVLGREDVGGKTGSTNDHRDAWFSGFGGPLATTVWVGRDDFRSLGYREYGGRAALPIWIDYMRVALKDAPIARNDPPSGMVQATLNGATEWIKVEDLDRMQEFDFDQHDPQADDAAFDIF
>CP019797.1|AUZ56587.1|2761777_2762836_-|pilus-assembly-protein-PilM
MGLIPKSQPPIIGVDISSTAVKLLQLARSGNRFRVEHYAVEPLPPNAVVEKNIVEVEAVGEAIRRAVARSGTRAKGAAAAVAGSAVITKVIPMPADLDEADMEAQVELEAVNYIPYPIEEVSLDFEVLGPVPNNPEMVQVLLAASRSENVELRQSALELGGLVAKVMDVEAFAIENAFALVASELPVASDGVVALVDIGATMTTLNVLRGGRSLYSREQVFGGKQLTDEVMRRYGLSYEEAGLAKRQGGLPESYEVEVLEPFKEATVQQIGRLLQFFYAGSEFNRVDHIVLAGGCASLPGLPVMVEEQLGVSTSVANPLAQMTLGQKVQAHALAQDAPALMIATGLALRGFD
>CP019797.1|AUZ55744.1|2761064_2761778_-|fimbrial-protein
MARINLLPWRAERRKQRQREFYTMLGLAAVAGVLMSLLLYFYYDGQVSGQNERNAYLEAEIAKVKEQNKEIDRLDSQKKRLLDRKQVIEELQGKRSQMVHLFDALVRTIPDGVVLTALKQEGETLTLEGRTQSNARVSTYMRNLESSGWMSNPELSVIEAKAQEPSGSAVDIKSLPYVFTLKVKLPAPGENAAQGNVAPNADAAAPAATPAAAADPAAPAPAAPAPAADTAQKEARP
>CP019797.1|AUZ55743.1|2760390_2761068_-|fimbrial-protein
MSQKKSSFNNLDLNNIGNWPQGPKLVFCALLALLILGLSYLLVIRGTAEELEGLEAKEVELRASFEKEQQRAVNLEPLKQQLAQMEQVLQQMLRQLPSKTEMPDLIIDVSQTALSSGLNNELFKPGDEQLKEFYAEKPIALRLVGSYHQFGAFVSGVASLPRVVILTMHDINLKPKDPKAGISARSGALELSGTVKTYRYLDDNELADQEKKAADEEAARKKGGK
>CP019797.1|AUZ55742.1|2759854_2760391_-|fimbrial-protein
MKGSLRIRALCAVLLLLAASGCSRGITSTPGDAPNLEKWVADVRARPATPLEPLPVMQQFETFEYSAQGLRDPFSDAWASADGNSALRPDPNRRKEPLEAFPLDSLDMVGTIGKGAAMVALVMGPDKVTYRVRPGVYLGQSDGRVTSVREDGIELIELVPDGAGGWLERPASLALDDR
>CP019797.1|AUZ55741.1|2757943_2759833_-|fimbrial-protein
MTFSKALSLRPARRHAMVNARALGVALALACGSPFAAFAADLAPAAAAQPAATVAVTKVDFKRGDDGAGRLILQFDGQGASPDLRTQGNDIVVDMGNATLPAALQRPLNVVDFATPVQRIDARPSGHGSQLVLSTQGAFESLAYQSGNEYVVEISPRQAPSATGAVTAQTVAQAAATVAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNVVASDTVQGNVTLRLVNVPWDQALDIVLRAKGLDKRRDGGVIWVAPQPELAKFEQDKEDARIAIEERENLATDYIQINYHSAEAIFKALTEAKGIGNAGAGGGGTGGGSQHENGFLSKRGMIVADERTNTLMISDIPKKIAQMRELIAVIDRPVDQVLIEGRIVIASDTFARDLGAKFGIQGRRIGDRTQAISGSLGGNSSIINNGIVSNEGLNVNLPAKSYTESPAGAIAYTLLGANFALDVELSAMQEEGRGEVVSNPRIVTANQREGVIKQGKEIGYVTISGGGGAGGAPTANVQFKEALLELKVTPTITQDNRVFLNMNVKKDEIDRFLDVTDFGTVPIINRREINTAVLVDDGQTVVIGGVYEFNDRSSVAKVPFLGDVPFLGNLFKKRGRAKDKAELLVFVTPKILRVAKPH
>CP019797.1|AUZ56586.1|2755825_2756743_-|ATPase
MAAPGSRLPATEGIAPSLAELIALRRAAMPARGPRRGRRGASARALSAQRGRGMEYAESREYVAGDDARHIDWKLSARTGFTHTKTFQAERERLTLLVADTAPALYFGTRVRFKSVQAARAGAVAAWSALRDGDRVAALCAGGGAALVPPAGGMRGVLRVLDALVRWYGAAAVDDAGLQPALERAARLLHPGARVLVLADPGSALAVAPATWSALSMHVDVRLLLLVDPLEMRPPHCVLPVLAPGARMELDLAAGATRDAWHAAFVAPVEALCRSLPGRRIQVQVLASDDASDAWLAPTAARSGR
>CP019797.1|AUZ55740.1|2755373_2755829_-|hypothetical-protein
MIATALPLRDVHLPAAPGVWPPAPGWWLLLGVLLLGLAVFVALRLRRRHRRRRWQSLFDAALAAASAPAARVGRASDLLRRAARRCDPAAALLQGEAWLRFLDGPARRDFSQGEGRLLLDGGFRRQVDEAQATRACALARGRFVDLMERRR
>CP019797.1|AUZ55739.1|2754378_2755374_-|hypothetical-protein
MERLHALLGGLPEFAWPWLWLAVPLPLLMALWPRAAGNGPALRVPWPPARLQATAAHRHGPWPRTLLLWLAWLCLCAAAARPQQLGDAVEPPRQTRQMMLAVDLSGSMSEGDMLLGGRVVDRLTAAKAVLADFLDRREGDSIGLLVFGQRAYALTPLTRDRASVREQLRDSVVGLAGRETALGDAIALAVKRLRGQPEGQRVLILLTDGVNTAGVIDPLKAAELARAEGVRVHTIAFGGNGGVSLFGMRLPGAEDPIDEDTLARIARDTGGRFFRARDTGELVGIYAELDRLEPVRSAGPALRPRLERYAWPLAAALLLGLLALAWPERRR
>CP019797.1|AUZ55747.1|2766815_2768090_-|citrate-(Si)-synthase
MSDLDQVTLNAGDTSVVLPVVKPVLGNDCVDISKLTKETGLFTYDSGYTATASCKSAITYIDGDKGVLLYRGYPIEQLAEKSSFVEVAYMLVNGERPDAAQLKAFEAELAEEAGVDASINTLIGSFAKDAHPMAILAAAIAQLSAKYHDSLDLADAEQRRKAAVRLIAKVPTLSSLIYRHGKGLPANTPDTSLDYVSRFLKQTFESADGQYELNPHVVKALDLLFILHADHEQNASTSTVRLVGSTGANPYASVAAGVTALWGPAHGGANEAVLKMLEEIGSADNVESAVLKAKDKTSGFRLMGFGHRVYKNFDPRAKVIGEMTKQVLGQLGVTDPLLDVAIKLEQAALQDDYFVARKLYPNVDFYSGIIYKALQIPTEMFTVMFALGRTAGWVSHWLEQQVDPEMKIGRPRQVYTGHAVRDYT
>CP019797.1|AUZ55748.1|2768454_2768697_-|50S-ribosomal-protein-L31
MKADIHPDYHNVVFHDVTSDFKFLTRSTMSSKETVKWEDGEEYPLIKVEISSASHPFYTGKHKVIDTSGRIDKFQKRYAR
>CP019797.1|AUZ55749.1|2768780_2769722_-|nucleoside-hydrolase
MSKKIPLLIDTDPGVDDALALLMAFADARHDVVGLTVAAGNVGLGYTVRNALKLCEVAGRGDVPVFAGAPDPLVYPAEDAAHVHGRDGFGDVDLPAAARAVEDEHAALAILRLSHQYAGELLLVALGPLTNIALALKLDPTLPQRVKRFLVMGGAITGHGNITPVAEFNIAFDPEAAHIVFTAFPHVEVADWEATVAHGLLHRNVEQWLAADTDKARFYELISRQTRLWSEDSRGEYWYAADALAMAWALQPEGATRLEQRPLAIEMAGGRTRGATVVDWNRQTGAADNTTLLIGYDQARFERQVQRALGLDS
>CP019797.1|AUZ55750.1|2769787_2771932_-|ATP-dependent-DNA-helicase-RecG
MARTRAAAPALAASGETPVTALPGVGPAVAAKLQARGIGSLQDLWLHLPLRYEDRTRLSAIATLLPGSAAQVEGRVVAVERGFRYRPVLRVALEDDSRGTLVLRFFHFRAAQVAQFAVGARLRCYGTPRPGQHGLEIVHPSYRMLGDGEEAGLGDALDPVYPVVEGIGPATLRKLIGQALERLPGEAALELLPAALLDGLALPSLRQALLTMHRPPADADVAALAAGTHPAQRRLAMEELLAHHLSLRRQRIALQQHHAPALTGGDKRVRQLRQSLPFRLTGAQQRVFAQIRQDLARPHPMLRLVQGDVGSGKTVVAALAAMLAVEQGKQVALAAPTELLAEQHLANLRGWLEPLGVQVAWLAGKVTGKARARALEDIASGRAQVVVGTHALMQDSVVFHDLALAIVDEQHRFGVHQRLALRDKGADGRSVPHQLVMTATPIPRTLAMAAYSDLDVSAIDELPPGRTPVQTIVISAERRPELVERIRAACAQGRQAYWVCTLIDESGDDGGGPAANAGRMEAVAAQATFEALSAQLPGVRVGLVHGRMKAAEKQAAMRAFKAGETGLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLMYQGPLSAMARQRLETMRQTSDGFVIAEKDLELRGPGELLGTRQTGLAAFRVADLARDAGLLPGVHALAERLLADAPAVADRVVARWVGGAARYASA
>CP019797.1|AUZ55751.1|2771941_2772325_-|reactive-intermediate/imine-deaminase
MSRQIINTANAPAAIGPYSQAVRAGNTVYFSGQIPLDPATGEIVAGDVAAQARRAFDNLKAVATEAGGSLDQIVRLGLYLTDLGEFAKVNAVMQEYFQAPFPARSTIEVSGLPKGAAFEVDAVMILD
>CP019797.1|AUZ55752.1|2772891_2775051_-|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis(diphosphate)-3'-diphosphatase
MNPGPSAQVAAPAGGAVPDYVLQLERAASYLPAEQLPMLRRAWEVGASAHAGQTRKSGEPYITHPVAVAGILAELGLDVEALVAAILHDTIEDTPLTYDELAGEFGQTVAELVEGVTKLDKLRFRDRQEAAAESFRKMLLAMSRDLRVIMIKLADRLHNMRTLGAQSAEARRRIAMETLDIYAPIAQRLGMSLIKSELQNLGFKALYPWRHAILEKHIRSQPVVRREAMAQVEVQLSQRLAREGLEHRLVSRIKTPWSIYTKMREENKTFDQVMDVFGFRLVMRSVPSCYHALGAVHAAFKPLDGRFRDFIAIPKANGYQSLHTVLFGPYGSPIEVQIRTEEMDLIAERGVAAHWTYKFGGDSPNSAQSRAHAWIVELIDSQRSAGSSLEFLDNVKVDLFPDEVYLFTPKGKILALPRNSTALDFAYAVHTDIGNRAVASRVDKKLVPLRTKLASGQTVEVITARSATPKPQWLEFVVSSKARTAIRHQLKQLEHEDAVQLGHRMLDRALEAMDSSIERLPKGRLDAFLGEHRYPRLEAFLADVALGNWMPTQAAQALMAHGEPRAGGTTQRAQEKILINGSERGVVSFAGCCQPIPGDEIMGYHTAGKGIVVHRMDCPNLAELRKSPERWVPIGWDSSVVGDYDTALVVEVENGTGVLAQLAAAIAQSQSNIERVDYLDRDFNAAVLCFNIQVRDRTHLAEVMRRLRRLSVVQSVRRQ
>CP019797.1|AUZ55753.1|2775307_2775607_-|DNA-directed-RNA-polymerase-subunit-omega
MARITVEDCLEVVNNRFELVMMASKRARQLANGVQATLDNSETEDKPTVLALREIAARKIDNALIEEVEKAERERAEREALEWAAAEVVADEDMSKNDD
>CP019797.1|AUZ55754.1|2775794_2776406_-|guanylate-kinase
MRGTLFIVAAPSGAGKSSLVNATLARDAQIALSISFTSRAMRPGEENGRHYHFVSAAEFERMIAAGDFFEYARVHGDWKGTARQSVEPQLAAGKDVLLEIDWQGARQVREKVPDAVSVFILPPSKQALDDRMRKRGQDSEAVMAQRLAAAREEMLHYDEFDYVIVNEVFDTAVDEMCAIFTASRLRRAQQQARHGGLIRSLLD
>CP019797.1|AUZ56588.1|2776510_2777605_-|hypothetical-protein
MRAFGVPGVAIAVVDQGELAWHRGFGVADVDSGAPVDADSVFECASLSKPVFAYLVLQLVDAGALALDRPLVDYHRPDFLADDDPQLARITVRDVLRHSSGLPGWRAHPDRDPLRTIAEPGQRVDYSGEAFFWLQRVVETVTGQALDQWAQQHLFGPAGMHGSTYTWNAHAARHSVTGVPAPGARPVVQTFRAQWPLLQPLAEASGKPLAAWTWDDAVRALPQAQAAAPAGMFVWPGDLLANAAASLRGPVQDYARFIAHIMRHPVRQDWEIGEATRQAMLTPQLAVRPGWLDKGLGWNLERIDADTRWFFHGGANAGRYKTFAVGDPRHGRGLVVMTSGGGGTGVYQRIVRAATGRDMLAFDL
>CP019797.1|AUZ55755.1|2778042_2778903_-|YicC-family-protein
MIRSMTAYAGGERGTRWGTLGCELRSVNHRFLEVGVRLPEELRALEPQLRERVAARISRGKLDLVMRLRAPDAAPTLAVDEALVEQLGSLARRLHSRFPDMRIGFTELLAYPGVLRGEAVDAAALQAEALALLDETLDGFVAAREREGAKLTAAISERVDAIERIAGEVRGLIPAIREGQRAKLAARLADLPHPVDPGRAEQELVLWLQKLDVDEELDRLVSHIGEIRRVLRQREPVGRRLDFLLQEFNREANTLGSKSVDSRTSNAAVELKVLIDQIREQVQNLE

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	244483-244513	5	0.839
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	57654-57684	5	0.839
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	261371-261401	5	0.839
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	531428-531458	5	0.839
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	524428-524458	6	0.806
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	28863-28893	6	0.806
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	194590-194620	6	0.806
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	244701-244731	6	0.806
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	533604-533634	6	0.806
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	686377-686407	6	0.806
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	NC_009475	Bradyrhizobium sp. BTAi1 plasmid pBBta01, complete sequence	156515-156545	6	0.806
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_CP031420	Nocardia farcinica strain W6977 plasmid unnamed2, complete sequence	26829-26862	6	0.824
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_LN868942	Nocardia farcinica strain NCTC11134 plasmid 5, complete sequence	23110-23143	6	0.824
CP019797_6	6.1|2766420|29|CP019797|CRISPRCasFinder	2766420-2766448	29	NZ_LN890332	Leuconostoc gelidum subsp. gasicomitatum KG16-1 isolate LEKG1 plasmid II, complete sequence	19986-20014	6	0.793
CP019797_6	6.1|2766420|29|CP019797|CRISPRCasFinder	2766420-2766448	29	NZ_CP042398	Leuconostoc citreum strain CBA3623 plasmid unnamed5, complete sequence	10662-10690	6	0.793
CP019797_6	6.1|2766420|29|CP019797|CRISPRCasFinder	2766420-2766448	29	NZ_CP035269	Weissella cibaria strain SRCM103448 plasmid unnamed2, complete sequence	8188-8216	6	0.793
CP019797_1	1.2|533822|32|CP019797|CRISPRCasFinder	533822-533853	32	NZ_CP033873	Caulobacter sp. FWC26 plasmid p1, complete sequence	256046-256077	7	0.781
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP030128	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence	83580-83610	7	0.774
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1174414-1174444	7	0.774
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	37412-37442	7	0.774
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	JN699011	Mycobacterium phage Stinger, complete genome	62885-62915	7	0.774
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	877539-877572	7	0.794
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	935582-935615	7	0.794
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	57967-58000	7	0.794
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1136791-1136824	7	0.794
CP019797_6	6.1|2766420|29|CP019797|CRISPRCasFinder	2766420-2766448	29	NZ_CP026273	Klebsiella oxytoca strain KONIH4 plasmid pKOX-ea2b, complete sequence	82950-82978	7	0.759
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	MF919504	Mycobacterium phage DmpstrDiver, complete genome	87246-87276	8	0.742
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	74196-74226	8	0.742
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	NC_047958	Burkholderia phage vB_BmuP_KL4, complete genome	29054-29084	8	0.742
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	NC_024123	Pseudomonas phage KPP25 DNA, complete sequence	25051-25081	8	0.742
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	95024-95057	8	0.765
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NC_011879	Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence	421251-421284	8	0.765
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	153929-153962	8	0.765
CP019797_4	4.5|2199893|34|CP019797|CRISPRCasFinder	2199893-2199926	34	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	827686-827719	8	0.765
CP019797_3	3.2|1839729|37|CP019797|PILER-CR	1839729-1839765	37	NC_022001	Streptomyces collinus Tu 365 plasmid pSCO1, complete sequence	33026-33062	9	0.757
CP019797_3	3.2|1839729|37|CP019797|PILER-CR	1839729-1839765	37	NC_010851	Streptomyces sp. FR1 plasmid pFRL1, complete sequence	27038-27074	9	0.757
CP019797_3	3.2|1839729|37|CP019797|PILER-CR	1839729-1839765	37	MT451984	Microbacterium phage Nebulous, complete genome	2625-2661	9	0.757
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP029211	Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence	343568-343598	9	0.71
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	140075-140105	9	0.71
CP019797_4	4.2|2199725|31|CP019797|CRISPRCasFinder	2199725-2199755	31	LR606148	Rhizobium sp. Q54 genome assembly, plasmid: 5	257041-257071	9	0.71
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	67532-67565	9	0.735
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	462144-462177	9	0.735
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_LR536452	Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 3	63370-63403	9	0.735
CP019797_4	4.5|2199893|34|CP019797|CRISPRCasFinder	2199893-2199926	34	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	254899-254932	9	0.735
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	1702283-1702313	10	0.677
CP019797_4	4.1|2199671|31|CP019797|CRISPRCasFinder	2199671-2199701	31	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	1932757-1932787	10	0.677
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	484360-484393	10	0.706
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	390055-390088	10	0.706
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_CP013856	Pseudonocardia sp. HH130630-07 plasmid pLS2-2, complete sequence	34158-34191	10	0.706
CP019797_4	4.5|2199893|34|CP019797|CRISPRCasFinder	2199893-2199926	34	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	7410-7443	10	0.706
CP019797_4	4.5|2199893|34|CP019797|CRISPRCasFinder	2199893-2199926	34	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	287710-287743	10	0.706
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	NZ_CP033583	Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence	61550-61583	11	0.676
CP019797_4	4.3|2199779|34|CP019797|CRISPRCasFinder	2199779-2199812	34	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	378104-378137	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	356495-356528	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	356471-356504	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1645209-1645242	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1662755-1662788	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	356278-356311	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	356265-356298	11	0.676
CP019797_4	4.4|2199836|34|CP019797|CRISPRCasFinder	2199836-2199869	34	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1628090-1628123	11	0.676

1. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

gtgaaggc-ccgggacatcaaggcgctggcca	CRISPR spacer
-tggacgcgcccggccatcaaggcgctggcca	Protospacer
 **.* ** ** ** *****************

2. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

gtgaaggc-ccgggacatcaaggcgctggcca	CRISPR spacer
-tggacgcgcccggccatcaaggcgctggcca	Protospacer
 **.* ** ** ** *****************

3. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

gtgaaggc-ccgggacatcaaggcgctggcca	CRISPR spacer
-tggacgcgcccggccatcaaggcgctggcca	Protospacer
 **.* ** ** ** *****************

4. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.839

atcgag--ctggacaacgtcggcgcgctgcacg	CRISPR spacer
--cgaggcccggacaatgtcggcgcgctgctcg	Protospacer
  ****  *.******.************* **

5. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.806

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gagaaggcccgggagatcatggcgcgcacca	Protospacer
* ************ **** *****  .***

6. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.806

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gagaaggcccgggagatcatggcgcgcacca	Protospacer
* ************ **** *****  .***

7. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 6, identity: 0.806

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gagaaggcccgggagatcatggcgcgcacca	Protospacer
* ************ **** *****  .***

8. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 6, identity: 0.806

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gagaaggcccgggagatcatggcgcgcacca	Protospacer
* ************ **** *****  .***

9. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.806

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gagaaggcccgggagatcatggcgcgcacca	Protospacer
* ************ **** *****  .***

10. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.806

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gagaaggcccgggagatcatggcgcgcacca	Protospacer
* ************ **** *****  .***

11. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to NC_009475 (Bradyrhizobium sp. BTAi1 plasmid pBBta01, complete sequence) position: , mismatch: 6, identity: 0.806

atcgagctggacaacgtcggcgcgctgcacg-	CRISPR spacer
gtcgagctggccaaagtcggcgcgc-ggacat	Protospacer
.********* *** ********** * **. 

12. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_CP031420 (Nocardia farcinica strain W6977 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.824

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
gtgccagtcggcggggtgcgcggcgataccggcg	Protospacer
** *  *********************.**.* *

13. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_LN868942 (Nocardia farcinica strain NCTC11134 plasmid 5, complete sequence) position: , mismatch: 6, identity: 0.824

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
gtgccagtcggcggggtgcgcggcgataccggcg	Protospacer
** *  *********************.**.* *

14. spacer 6.1|2766420|29|CP019797|CRISPRCasFinder matches to NZ_LN890332 (Leuconostoc gelidum subsp. gasicomitatum KG16-1 isolate LEKG1 plasmid II, complete sequence) position: , mismatch: 6, identity: 0.793

gcgggccatcgacaagcgatgtcaaaaac	CRISPR spacer
gcgggtcatcgacaagcgatgaccgtagc	Protospacer
*****.*************** * . *.*

15. spacer 6.1|2766420|29|CP019797|CRISPRCasFinder matches to NZ_CP042398 (Leuconostoc citreum strain CBA3623 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.793

gcgggccatcgacaagcgatgtcaaaaac	CRISPR spacer
gcgggtcatcgacaagcgatgaccgtagc	Protospacer
*****.*************** * . *.*

16. spacer 6.1|2766420|29|CP019797|CRISPRCasFinder matches to NZ_CP035269 (Weissella cibaria strain SRCM103448 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

gcgggccatcgacaagcgatgtcaaaaac	CRISPR spacer
gcgcgccatcgacaagcgatgaccgtagc	Protospacer
*** ***************** * . *.*

17. spacer 1.2|533822|32|CP019797|CRISPRCasFinder matches to NZ_CP033873 (Caulobacter sp. FWC26 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

ggcgtcgccggaggcaggccgcgatgggggcg	CRISPR spacer
cgggtccccggaggcaggcggcgatgtctgcg	Protospacer
 * *** ************ ******   ***

18. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP030128 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
gtgaaggcccaggacatcaaggccgcgatcc	Protospacer
**********.************  .*..* 

19. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

atcgagctggacaacgtcggcgcgctgcacg	CRISPR spacer
gtgtggcgtgacaacgccggcgcgctgcacg	Protospacer
.*  .**  *******.**************

20. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

atcgagctggacaacgtcggcgcgctgcacg	CRISPR spacer
ggcgagctgcacaatgtcggcgcgcaacccg	Protospacer
. ******* ****.********** .* **

21. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to JN699011 (Mycobacterium phage Stinger, complete genome) position: , mismatch: 7, identity: 0.774

atcgagctggacaacgtcggcgcgctgcacg	CRISPR spacer
gtggtgctggacgacatcggcgcgctgctgg	Protospacer
.* * *******.**.************  *

22. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.794

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
ctcggcgtcgccggggtgcgcggcgagggccgtg	Protospacer
 ** ****** *************** * * * *

23. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.794

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
ctcggcgtcgccggggtgcgcggcgagggccgtg	Protospacer
 ** ****** *************** * * * *

24. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 7, identity: 0.794

gtccgcgtcggcggggtgcgcggcgatgccaggg-	CRISPR spacer
ggccgggtcggcggggtgcgcgccga-accacagc	Protospacer
* *** **************** *** .*** .* 

25. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.794

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
gtgccagtcggcggggtgggcgccgatgcccgcg	Protospacer
** *  ************ *** ******* * *

26. spacer 6.1|2766420|29|CP019797|CRISPRCasFinder matches to NZ_CP026273 (Klebsiella oxytoca strain KONIH4 plasmid pKOX-ea2b, complete sequence) position: , mismatch: 7, identity: 0.759

gcgggccatcgacaagcgatgtcaaaaac	CRISPR spacer
tgcagccatcgacaagcgttgtcaaagtc	Protospacer
   .************** *******. *

27. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to MF919504 (Mycobacterium phage DmpstrDiver, complete genome) position: , mismatch: 8, identity: 0.742

-----gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
tatctgcg-----ccgggacatcaaggccctggccg	Protospacer
     *.*     *************** ******.

28. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 8, identity: 0.742

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
ccggaggcccgggacggcaaggcgctgcgcg	Protospacer
 .*.***********. **********  *.

29. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to NC_047958 (Burkholderia phage vB_BmuP_KL4, complete genome) position: , mismatch: 8, identity: 0.742

atcgagctggacaacgtcggcgcgctgcacg	CRISPR spacer
cgcctgctgcgcaacgtcggcgcgctgcgct	Protospacer
  *  **** .*****************.* 

30. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to NC_024123 (Pseudomonas phage KPP25 DNA, complete sequence) position: , mismatch: 8, identity: 0.742

atcgagctggacaacgtcggcgcgctgcacg	CRISPR spacer
atcgagctgcgcaacgtcggcgctggcatcg	Protospacer
********* .************      **

31. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 8, identity: 0.765

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
atccgcgttgtcggggtgcgcggcgaccgccgtg	Protospacer
.*******.* ***************.  * * *

32. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NC_011879 (Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence) position: , mismatch: 8, identity: 0.765

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
caggaacggcgcgtcgtgcagggcaatcagggca	Protospacer
* ***** ***** ************.  **. *

33. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP034149 (Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence) position: , mismatch: 8, identity: 0.765

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
ctgcattcgcgcaacgtgcagggcaacgtcgatc	Protospacer
*** * ..****.**************** **  

34. spacer 4.5|2199893|34|CP019797|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 8, identity: 0.765

gccgacatcagcggcgtccgcggcacggtcggcc	CRISPR spacer
accggcgatggcggcgtcggcggcacgctcggcc	Protospacer
.***.*. ..******** ******** ******

35. spacer 3.2|1839729|37|CP019797|PILER-CR matches to NC_022001 (Streptomyces collinus Tu 365 plasmid pSCO1, complete sequence) position: , mismatch: 9, identity: 0.757

-gcatgccggccggcgcctacaccatcgccgccaccta	CRISPR spacer
aggacg-cggccggcgcctacacctccgccgccgacag	Protospacer
 * *.* ***************** .*******. * .

36. spacer 3.2|1839729|37|CP019797|PILER-CR matches to NC_010851 (Streptomyces sp. FR1 plasmid pFRL1, complete sequence) position: , mismatch: 9, identity: 0.757

-gcatgccggccggcgcctacaccatcgccgccaccta	CRISPR spacer
aggacg-cggccggcgcctacacctccgccgccgacag	Protospacer
 * *.* ***************** .*******. * .

37. spacer 3.2|1839729|37|CP019797|PILER-CR matches to MT451984 (Microbacterium phage Nebulous, complete genome) position: , mismatch: 9, identity: 0.757

gcatgccggccggcgcctacaccatcgccgccaccta	CRISPR spacer
tgatgagcgacggcacctacaccatcgccgccatctt	Protospacer
  ***   * ****.******************.** 

38. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP029211 (Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence) position: , mismatch: 9, identity: 0.71

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
cgcccgagccgggacgtcaaggcgctggccg	Protospacer
     *. *******.**************.

39. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 9, identity: 0.71

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
cctgaggcccgggacggcaaggcgctgcgcg	Protospacer
 . .***********. **********  *.

40. spacer 4.2|2199725|31|CP019797|CRISPRCasFinder matches to LR606148 (Rhizobium sp. Q54 genome assembly, plasmid: 5) position: , mismatch: 9, identity: 0.71

atcgagctggacaacgtcggcgcgctgcacg	CRISPR spacer
gacgagctggacaaggtcggcacgcaagtct	Protospacer
. ************ ******.*** .  * 

41. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NC_018022 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence) position: , mismatch: 9, identity: 0.735

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
ctgcgcgtcggcggtgtgcgcgtcgatgatgctg	Protospacer
 * *********** ******* ***** ..  *

42. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 9, identity: 0.735

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
cacctcgtcgtcggggtgcgcggcgaccaccagg	Protospacer
  ** ***** ***************.  * .**

43. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_LR536452 (Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 3) position: , mismatch: 9, identity: 0.735

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
cccggcgtcggcgcggcgcgcggcgatgaggcgg	Protospacer
 .* ********* **.***********  . **

44. spacer 4.5|2199893|34|CP019797|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.735

gccgacatcagcggcgtccgcggcacggtcggcc	CRISPR spacer
acccggatcagcggcgtccgcggcccgatccgaa	Protospacer
.** . ****************** **.** *  

45. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 10, identity: 0.677

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
cccggcaacctggacatcaaggcgctggcct	Protospacer
 . .. . ** ******************* 

46. spacer 4.1|2199671|31|CP019797|CRISPRCasFinder matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 10, identity: 0.677

gtgaaggcccgggacatcaaggcgctggcca	CRISPR spacer
cccggcaacctggacatcaaggcgctggcct	Protospacer
 . .. . ** ******************* 

47. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
gcggtagtcggcgtagtgcgcggcgatgccgtag	Protospacer
*.    ******* .***************. .*

48. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
atccgcgtcggcgtgctgcgcggcgggcccgtca	Protospacer
.************ * *********.  **.  .

49. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_CP013856 (Pseudonocardia sp. HH130630-07 plasmid pLS2-2, complete sequence) position: , mismatch: 10, identity: 0.706

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
cacagcggcggtggggtgcgcggcgatgaacccg	Protospacer
  * *** ***.****************     *

50. spacer 4.5|2199893|34|CP019797|CRISPRCasFinder matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 10, identity: 0.706

gccgacatcagcggcgtccgcggcacggtcggcc	CRISPR spacer
ctcggtgagggcggcggcggcggcacggtcggcc	Protospacer
 .**...  .****** * ***************

51. spacer 4.5|2199893|34|CP019797|CRISPRCasFinder matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 10, identity: 0.706

gccgacatcagcggcgtccgcggcacggtcggcc	CRISPR spacer
ctcggtgagggcggcggcggcggcacggtcggcc	Protospacer
 .**...  .****** * ***************

52. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to NZ_CP033583 (Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence) position: , mismatch: 11, identity: 0.676

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
ccccgcgtcggcggggagcacggcgaacgggtga	Protospacer
 .************** **.******    . *.

53. spacer 4.3|2199779|34|CP019797|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 11, identity: 0.676

gtccgcgtcggcggggtgcgcggcgatgccaggg	CRISPR spacer
caggccgtcggccgggagcgcggcgatgcgctgc	Protospacer
     ******* *** ************   * 

54. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. * 

55. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. * 

56. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. * 

57. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. * 

58. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. * 

59. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. * 

60. spacer 4.4|2199836|34|CP019797|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.676

ctggaactgcgcgacgtgcagggcaacgtggaga	CRISPR spacer
gcaagcctgcgcggcgtccagggcaacgtgacgt	Protospacer
 .... *******.*** ************. *