CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025990	Actinoalloteichus sp. AHMU CJ021 chromosome, complete genome	43 crisprs	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas4,csa3,WYL,DEDDh,cas6,DinG,cas8c	3	141	2	0

1. CP025990

CRISPR-Cas detection and classification

Crispr_ID: CP025990_1

• CRISPR_ID: CP025990_1
• CRISPR_location: 123593-123864
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of CP025990_1

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAAGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAAGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAAGAC	CRT

spacers of CP025990_1

>1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTGGACATCTGGCCGCCCGACACCGGCTGGCTG
>1.2|123682|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GACTTCGCCGCCGTGGAGGTTTCCGCTGATGAC
>1.3|123743|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGCCCTTGCCCATGACCCGGATCGTCCCGGTG
>1.4|123804|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCGTCAAGGTCAATCGGGGTGCCCTGCATCGG

CRISPR arrays and Neighbor proteins around CP025990_1

CRISPR arrays

The CRISPR arrays of CP025990_1

>merge|CP025990|1|123593-123864|PILER-CR,CRISPRCasFinder,CRT
GGAACAGCCCCTCGTGCGCGGGGAAGACGTGGACATCTGGCCGCCCGACACCGGCTGGCTGGGAACAGCCCCGCGTGCGCGGGGAAGACGACTTCGCCGCCGTGGAGGTTTCCGCTGATGACGGAACAGCCCCGCGTGCGCGGGGAAGACCGGCCCTTGCCCATGACCCGGATCGTCCCGGTGGGAACAGCCCCGCGTGCGCGGGGAAGACGCCGTCAAGGTCAATCGGGGTGCCCTGCATCGGGGAACAGCCCCGCGTGCGCGGGGAAGAC

>CP025990|1|1|123593-123864|PILER-CR
GGAACAGCCCCTCGTGCGCGGGGAAGAC	GTGGACATCTGGCCGCCCGACACCGGCTGGCTG
GGAACAGCCCCGCGTGCGCGGGGAAGAC	GACTTCGCCGCCGTGGAGGTTTCCGCTGATGAC
GGAACAGCCCCGCGTGCGCGGGGAAGAC	CGGCCCTTGCCCATGACCCGGATCGTCCCGGTG
GGAACAGCCCCGCGTGCGCGGGGAAGAC	GCCGTCAAGGTCAATCGGGGTGCCCTGCATCGG
GGAACAGCCCCGCGTGCGCGGGGAAGAC

>CP025990|1|1|123593-123864|CRISPRCasFinder
GGAACAGCCCCTCGTGCGCGGGGAAGAC	GTGGACATCTGGCCGCCCGACACCGGCTGGCTG
GGAACAGCCCCGCGTGCGCGGGGAAGAC	GACTTCGCCGCCGTGGAGGTTTCCGCTGATGAC
GGAACAGCCCCGCGTGCGCGGGGAAGAC	CGGCCCTTGCCCATGACCCGGATCGTCCCGGTG
GGAACAGCCCCGCGTGCGCGGGGAAGAC	GCCGTCAAGGTCAATCGGGGTGCCCTGCATCGG
GGAACAGCCCCGCGTGCGCGGGGAAGAC

>CP025990|1|1|123593-123864|CRT
GGAACAGCCCCTCGTGCGCGGGGAAGAC	GTGGACATCTGGCCGCCCGACACCGGCTGGCTG
GGAACAGCCCCGCGTGCGCGGGGAAGAC	GACTTCGCCGCCGTGGAGGTTTCCGCTGATGAC
GGAACAGCCCCGCGTGCGCGGGGAAGAC	CGGCCCTTGCCCATGACCCGGATCGTCCCGGTG
GGAACAGCCCCGCGTGCGCGGGGAAGAC	GCCGTCAAGGTCAATCGGGGTGCCCTGCATCGG
GGAACAGCCCCGCGTGCGCGGGGAAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
CP025990.1|AUS77094.1|120032_120557_+|hypothetical-protein	unknown	unknown	gnl|CDD|274679
CP025990.1|AUS77092.1|118939_119506_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|334450
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|378243
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
CP025990.1|AUS77091.1|118032_118749_-|polyketide-cyclase	unknown	unknown	gnl|CDD|176908
CP025990.1|AUS77097.1|122307_123159_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77089.1|116016_116424_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|132706
CP025990.1|AUS77096.1|121295_121967_-|transcriptional-regulator	unknown	unknown	gnl|CDD|224647
CP025990.1|AUS77093.1|119565_120036_+|transcriptional-regulator	unknown	unknown	gnl|CDD|224647
CP025990.1|AUS77095.1|120678_121299_-|DNA-binding-protein	unknown	unknown	gnl|CDD|223340
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
CP025990.1|AUS77098.1|123194_123536_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS77090.1|116785_116968_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	1.6e-30	100.9	0.8
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	8.7e-61	200.6	0.0
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	1.6e-61	202.9	0.3
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	5.7e-44	144.8	1.4
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	4.5e-115	380.0	0.6
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	5.7e-105	344.9	0.1
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.4e-30	100.1	0.5
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.7e-119	394.3	1.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.76798e-34
CP025990.1|AUS77094.1|120032_120557_+|hypothetical-protein	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	0.00351382
CP025990.1|AUS77092.1|118939_119506_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	1.14858e-13
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.35097e-73
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.77767e-40
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.53404e-75
CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.54305e-166
CP025990.1|AUS77091.1|118032_118749_-|polyketide-cyclase	gnl|CDD|176908	cd08899, SRPBCC_CalC_Aha1-like_6, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	2.24661e-27
CP025990.1|AUS77097.1|122307_123159_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS77089.1|116016_116424_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|132706	TIGR03667, Rv3369, PPOX class probable F420-dependent enzyme, Rv3369 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	9.63172e-31
CP025990.1|AUS77096.1|121295_121967_-|transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	7.80904e-27
CP025990.1|AUS77093.1|119565_120036_+|transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	3.70436e-34
CP025990.1|AUS77095.1|120678_121299_-|DNA-binding-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	4.71621e-20
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	3.6946e-126
CP025990.1|AUS77098.1|123194_123536_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	5.35727e-124
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.41024e-40
CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066

Protein sequences

>CP025990.1|AUS77098.1|123194_123536_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS77097.1|122307_123159_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS77096.1|121295_121967_-|transcriptional-regulator
MRTYGDACGITRALDAVGERWALPVVRELVFGPRRYSDLAAALPGVSTNILGTRLRELAEVGVVVRRRLPPPTPVAVYELTAWGRALEPVLIALGRWAAHTPVDLAAQVLSPSSFALALRTTFDASLAAGRTVAVRLEMGEDVFDARIEEGAFHIARAAPDSRPPAVRVAAPPAVLSDLTFGSLSVEAAERRQLAVVSGPHADVESLLSCFVLPDPPPEEGHS
>CP025990.1|AUS77095.1|120678_121299_-|DNA-binding-protein
MSKVVVDISMSLDGFVTGPNAGPDQGLGEGGEPIHRWVMPEEPSPEDSALLDAAFRATGAVVMGRRTFDVIDGAAGWKDDLGYGYKQDQSQAPPNFVVTHEPPADPRHQTGFTFVTEGVAAAVAAAREVAGDRETVIMGGGDVCGQALALNLVDELRIHLSPVLMGSGTPLFAHIDQRVLLSQATVAVTPNATHLTYQLPRDEREA
>CP025990.1|AUS77094.1|120032_120557_+|hypothetical-protein
MTTPARAALIGRDTPPGSTPIPWEEARDSFAAASTYWWSTASGDHPTLRPVLSVWVDDAPHVSTSPVTRKSRPLAASPTTTLACQTGIADTVVEGTTTRVTDPATLRAVATAYATKYGWSPSVVGDALGGEEGAPTAGPPPYEVYRITPRRAYAFGIDEDHGARSTRWVFPDHS
>CP025990.1|AUS77093.1|119565_120036_+|transcriptional-regulator
MQRTRFGDMPCSIARTWNVIGEPWSPLILRDIYVGVRRFDDLQASLGISRKVLAERLTWLVDQQVLDRHPYSDRPTRHEYVLTPRGVELCDALLVLARWGDRWLAGADGPPALFRHRSCGATSHVTLHCSHCDQPMTASDVDVLDGPGAPAREETP
>CP025990.1|AUS77092.1|118939_119506_-|pyridoxamine-5'-phosphate-oxidase
METRIPAGDAVDLLGREGVGAPPARTEPLFGPSDASPFDDRAPLTPWVEAERWLTAASTVWLATVRPDGRPHAVPVFALWVDGALFVTLRPTSRKGRNLAANPQVSVIVSSEELELVLEGRAERVREVGALRRLTGVLAERFGWRLAVAGDGVVVDPDLPGEPEYGIYCVVPRVSFGFAGSSATRWSW
>CP025990.1|AUS77091.1|118032_118749_-|polyketide-cyclase
MAERACHWWDRVERFDDDGRTRGGGAADRGRAAMDLLDHINRTHRAVKRGTELNSVILTRAYDTTLTELWDACVNPERLPRWFEPVSGDLREGGRYRLEGRGIEGTIEVCVPRERLRVTWEDSGAGSFVEVTLREEGDQAVLRVEHVQAGGDFWDTFGPSATGVGWDGSVLSLALHLAGDPRATPEEMAKVGASEEGVEFMRRTASAWADADVEAGADPDHARGTADRTFAFYTGAEQ
>CP025990.1|AUS77090.1|116785_116968_-|hypothetical-protein
MAWRPGVPAFPVEHGHFAASSPGEPESREDEELGAYYALTQLNGDTGRALHALALGGFAT
>CP025990.1|AUS77089.1|116016_116424_+|pyridoxamine-5'-phosphate-oxidase
MTTNSPLEGLSEKAEDRVLWLGTVTPSKRPALRPVWFVYVDEKLVVFSEPHAAKVRHLRANPEVVVTFHTDPSAGHIRVVSGRAEVSLDGPPASSIPEFLDKYEDLYPVAGYTRHSFDTALSARITITPTRSWGW
>CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVVVVTACPVGLRGHLTRWLLEISPGVFVGGITARVRALLWGRVQEMVKTGRAIMVYNADTEQGLAFEVHGHEWTPVDHEGVQLMLRPAQRKRSAPKQRAGWSTASKRRRYGRGQKSE
>CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTEIPGARPVPISHLVRAADRLTFVYLEHCVVHRDANAITSRDERGTFHIPAATLSVLMLGPGTTISHHAVNLLAESGSTVVWVGEHGVRYYAHGRMLTDSSRLLERQAALVSNRTSRLSVARRMYGMRFPGEDVSASTMQQLRGREGARVRRLYREYAARTGIDWDGREYDPLDFAGGSPINQALSAAHTSLYGVVHAVIVSLGLAPGLGFVHTGNRRSFVYDIADLYKAQVTIPVAFEVAATDPDDIGAVTRRAVRDRMKDGQFLRTCVRDIVTLLRDPADGQLGDATDLQLPDVVMLWNEDGPDVPAGVSYGQDDEYDDGVNQDGEAS
>CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MHLTRFELNPARRATRHLLASPHRLHGAVMKAFPAAHREPTEDGRVLWRLDQTPKQTLLYIVSPHRPDLTHLVEETGWPATSTWDTRPYGPLLDQLAAGQEWAFRLTANPTRSVRRTSDVDTKRYGHLTVTQQTDWLLGRVERLGFSIPPAVENEPDVTVRGRDRRRFARQGTTVTLTLATYEGRLRVADPALFRRTLTHGIGSAKGYGCGLLTLARVRPT
>CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTALVLRFAAPLQSWGTSSRFTRRNTDLAPSRSGVIGLLASACGVRRADDLGAFTHLRVGVRVDQEGQLERDFQTARSLDGSQVMPLSTRFYLADAVFCVAVEGDAELLDRVRAALRRPAAPLFLGRRSCPPAGRLVEAVIDGDIRTALATVPWLASPAVRRKRASDREVTVDVVLDCPPDTPGSDVVRDVPISFDPRHRQYSWRSVHRDTVTIPNPDHSPPPDEHPHDPMELLGSPS
>CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSRTIIDLHVIQTVPPSNINRDDTGSPKTAMYGGVRRARVSSQAWKRATRDAFESLLDKENLGVRTKRIVELVAETIGERSPEHADRAQELAKSVLEAAGFKLKAPRKAPEGTPDEADFLVFLSRAQIINLADLAVESAREAGDGKTKIDKSEAKARADRSHSVDVALFGRMVANLPDLNVEAATQVAHALSVHGVTNEYDYYTAVDDHKKADEEEDAGAGMIGTIEFNSSTLYRYATIDVDQLQENLGDVEATRRAVEAFVRAFVSSMPTGKQNTFANRTLPDAVLVVARETQPINLVGAFEEAVTAREQGGRISGSIRRIATHATDIHAAFDETPLRAWSFGVGERVEPLAEIGERVSLDVAVKGAGQLVAERLAP
>CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTGNHSEHPPLRKWVNEQTGRLQQEYVKDRSHAVAGLARLRRAVDTPPGVMPDILDLTYAPFMTQGWHSDQPSAQETAAHHAMTLFAVHQQSLRKHACVPGWGVGRAARALHPQAEISPTDPAARRFATLVTSTDLDELLVHLRGLVKLLRGAEIPLDYGLLADQLVRWHRFEDAPERIRRVWGREFHRVPNTESDTTPPSDNEKTEDAS
>CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSLPDPYDLVERPWLLVRDLDGEVTEKSLLDTLTQSETLAGLVGDIPTQQFAHLRLLLAVCHRAFGRGLDDDGWKRLWDEGVPQDQIKDYLEQHRSRFDLFHPAEPFMQVATLRTAKDEVFELNRIVADVPNGHPFFSTRLERDLTLSPAEAARWLVHCHAFDPSGIKSGAVGDSRVKNGKGYPIGTGWSGRLGGVAPEGDTLWRTLLLNLVLPTRENDLPAWEQGQRGPLGKEREPTGPVDLYTWQSRRIRLVGTGDRVTGVLVCNGDPLGPQNQHKHETHTSWRRSETQEKKLKSSTPVYMPLEHSPERVIWRGLTAMLPQTVTSNQRSEASDRLSPGVLDQIARLTSDRRLPRDYPLRLHTIGMTYGSQSSTTAEIVDDAISLHAALLDRELAHLKEVVLGCVRDAEKAAYAVGDLALNLAKACGSREEPNVNGRLGPKDTALELAYAALDPAFRRWLAARLPEDDPIDVKEQWHVAARAEMRAVGSRLIAEAPPTGWTGRLVKDKWLTIPVAERWFTFALNRALPMASPAQPPEKDEE
>CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3
MHQHLADSAGVARLLVREWLSPAVVDRLAAEFPGGREDVETLTVWLASVHDLLKCSPAFACQVPELANHMASRGLTVRRGIKADPERPRANHAVAGQRVVREWLEEELGFDFLGGAHELASVVGSHHGLPPDDTALHRLDGLEYLLGDRRWQEVRAHILGWSLDHLGGPQALVRFRGVRFSRPALALLTALVIVADWIASNSELFPLYPVGALDRAPGPDDTVTERRVAEAWSKLNLSPRWRAVPFDGDVAGLLRCRFERDRPRDVQIAAVRAAVEQPEPGLLIIEAPMGSGKTEAALLVAEVMAHRAGADGVIVALPTQATTDAMFGRVHTWLHRLDGIPDRASVSLAHGKAHLNDTYSGLVRRGRFASMGDDVERRGSSRRSQDDCEDPVVAHWWLSGRKKSGLAPFVVGTIDQLLFAALKSRHVMLRHLALAGKVVVVDEVHAYDVYMSQYLHRVLEWLGAYRVPVVLLSATLPDHRRAELLHAYDTGRGGDASCVPAGHPGYPVVSVSGGPPPTVLPLPPERTRVALDRLDDGQDTLVTYLRAKLADGGCAVVVHNTVGRVQETARRLSEEFGEDAVTIAHSRFLACDRAEIDRGLLRRFGPPESAPDRPPLHIVVASQVVEQSLDVDFDLMVTDLAPVDLLLQRMGRLHRHTRSRPTAVSSPRCAIVGVEDWAAEPARSHPGSRRVYGEHLLLRAAALVIDRDEIALPHDIAPLVQAGYGDTTLGPNSWQPAMTAAAQAAEETASRRAKDAETYRLGAPSETGALTGWLKAGVGDASEDTARGAAQVRDGAASLEVLVVERDAGGGLRTLPWVPGGGKQLPLDSKVPWDQARVVAACSLRLPLALSTPDVIDEVIDELEDNWFASFQANPLLSGQLVLTLDAERRTRLHDHILTYDRRRGLMHEPA
>CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS

Crispr_ID: CP025990_3

• CRISPR_ID: CP025990_3
• CRISPR_location: 135362-135695
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

Consensus repeat of CP025990_3

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT

spacers of CP025990_3

>3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TATGCCGGCGCCCTCCCGGGCGGTTCGGATCGC
>3.2|135451|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGCGGCGCCAGATGGCCGCTGCCTTGATCCAGC
>3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCCTGCCACTGCGCCAACGCCTCCTGCTTGAGG
>3.4|135574|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGACCGGTCCGTCCTCGTGGACGTCGCCACGAC
>3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCGCCGTGATCCGCGCGTCCTGCCTCCTCCGC

CRISPR arrays and Neighbor proteins around CP025990_3

CRISPR arrays

The CRISPR arrays of CP025990_3

>merge|CP025990|3|135362-135695|PILER-CR,CRISPRCasFinder,CRT
GGAACAGCCCCGCGTGCGCGGGGAGGACTATGCCGGCGCCCTCCCGGGCGGTTCGGATCGCGGAACAGCCCCGCGTGCGCGGGGAGGACTGCGGCGCCAGATGGCCGCTGCCTTGATCCAGCGGAACAGCCCCGCGTGCGCGGGGAGGACGCCCTGCCACTGCGCCAACGCCTCCTGCTTGAGGGGAACAGCCCCGCGTGCGCGGGGAGGACCGACCGGTCCGTCCTCGTGGACGTCGCCACGACGGAACAGCCCCGCGTGCGCGGGGAGGACGCCGCCGTGATCCGCGCGTCCTGCCTCCTCCGCGGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|3|3|135362-135695|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TATGCCGGCGCCCTCCCGGGCGGTTCGGATCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TGCGGCGCCAGATGGCCGCTGCCTTGATCCAGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCCCTGCCACTGCGCCAACGCCTCCTGCTTGAGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGACCGGTCCGTCCTCGTGGACGTCGCCACGAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCCGCCGTGATCCGCGCGTCCTGCCTCCTCCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|3|2|135362-135695|CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TATGCCGGCGCCCTCCCGGGCGGTTCGGATCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TGCGGCGCCAGATGGCCGCTGCCTTGATCCAGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCCCTGCCACTGCGCCAACGCCTCCTGCTTGAGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGACCGGTCCGTCCTCGTGGACGTCGCCACGAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCCGCCGTGATCCGCGCGTCCTGCCTCCTCCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|3|3|135362-135695|CRT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TATGCCGGCGCCCTCCCGGGCGGTTCGGATCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TGCGGCGCCAGATGGCCGCTGCCTTGATCCAGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCCCTGCCACTGCGCCAACGCCTCCTGCTTGAGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGACCGGTCCGTCCTCGTGGACGTCGCCACGAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCCGCCGTGATCCGCGCGTCCTGCCTCCTCCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|378243
CP025990.1|AUS77109.1|135948_136728_-|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|180295
CP025990.1|AUS77115.1|144200_145352_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
CP025990.1|AUS77113.1|142393_143131_-|thioesterase	unknown	unknown	gnl|CDD|225749
CP025990.1|AUS77117.1|145643_146510_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|224170
CP025990.1|AUS77114.1|143127_144204_-|hypothetical-protein	unknown	unknown	gnl|CDD|273757
CP025990.1|AUS77116.1|145355_145616_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|376348
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77112.1|138711_139851_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173851
CP025990.1|AUS77110.1|136724_137672_-|3-hydroxyisobutyrate-dehydrogenase	unknown	unknown	gnl|CDD|130753
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
CP025990.1|AUS77111.1|137668_138712_-|3-hydroxyisobutyryl-CoA-hydrolase	unknown	unknown	gnl|CDD|235533
CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS81362.1|139860_141360_-|methylmalonate-semialdehyde-dehydrogenase-(CoA-acylating)	unknown	unknown	gnl|CDD|143404

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	1.6e-30	100.9	0.8
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.4e-30	100.1	0.5
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	1.6e-61	202.9	0.3
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	5.7e-44	144.8	1.4
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	4.5e-115	380.0	0.6
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	5.7e-105	344.9	0.1
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	8.7e-61	200.6	0.0
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.7e-119	394.3	1.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.76798e-34
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.53404e-75
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.35097e-73
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.77767e-40
CP025990.1|AUS77109.1|135948_136728_-|enoyl-CoA-hydratase	gnl|CDD|180295	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional.	3.049e-153
CP025990.1|AUS77115.1|144200_145352_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	8.36634e-92
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.54305e-166
CP025990.1|AUS77113.1|142393_143131_-|thioesterase	gnl|CDD|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	2.36748e-75
CP025990.1|AUS77117.1|145643_146510_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein	gnl|CDD|224170	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism].	2.26297e-106
CP025990.1|AUS77114.1|143127_144204_-|hypothetical-protein	gnl|CDD|273757	TIGR01686, modular_polyketide_synthase, FkbH-like domain. This model describes a domain of a family of proteins of unknown overall function. One of these, however, is a modular polyketide synthase 4800 amino acids in length from Streptomyces avermilitis in which this domain is the C-terminal segment. By contrast, the FkbH protein from Streptomyces hygroscopicus aparently contains only this domain. The remaining members of the family all contain an additional N-terminal domain of between 200 and 275 amino acids which show less than 20% identity to one another. It seems likely then that these proteins are involved in disparate functions, probably the biosynthesis of different natural products. For instance, the FkbH gene is found in a gene cluster believed to be responsible for the biosynthesis of unususal "PKS extender units" in the ascomycin pathway. This domain is composed of two parts, the first of which is a member of subfamily IIIC (TIGR01681) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. All of the characterized enzymes within subfamily III are phosphatases, and all of the active site residues characteristic of HAD-superfamily phosphatases are present in this domain. The C-terminal portion of this domain is unique to this family (by BLAST).	1.31945e-77
CP025990.1|AUS77116.1|145355_145616_-|acyl-carrier-protein	gnl|CDD|376348	pfam00550, PP-binding, Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of the anguibactin system regulator AngR has the attachment serine replaced by an alanine.	7.44266e-05
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	3.6946e-126
CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS77112.1|138711_139851_-|acyl-CoA-dehydrogenase	gnl|CDD|173851	cd01162, IBD, Isobutyryl-CoA dehydrogenase. Isobutyryl-CoA dehydrogenase (IBD) catalyzes the alpha, beta- dehydrogenation of short branched chain acyl-CoA intermediates in valine catabolism. It is predicted to be a homotetramer.	0
CP025990.1|AUS77110.1|136724_137672_-|3-hydroxyisobutyrate-dehydrogenase	gnl|CDD|130753	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase. 3-hydroxyisobutyrate dehydrogenase is an enzyme that catalyzes the NAD+-dependent oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde of the valine catabolism pathway. In Pseudomonas aeruginosa, 3-hydroxyisobutyrate dehydrogenase (mmsB) is co-induced with methylmalonate-semialdehyde dehydrogenase (mmsA) when grown on medium containing valine as the sole carbon source. The positive transcriptional regulator of this operon (mmsR) is located upstream of these genes and has been identified as a member of the XylS/AraC family of transcriptional regulators. 3-hydroxyisobutyrate dehydrogenase shares high sequence homology to the characterized 3-hydroxyisobutyrate dehydrogenase from rat liver with conservation of proposed NAD+ binding residues at the N-terminus (G-8,10,13,24 and D-31). This enzyme belongs to the 3-hydroxyacid dehydrogenase family, sharing a common evolutionary origin and enzymatic mechanism with 6-phosphogluconate. HIBADH exhibits sequence similarity to the NAD binding domain of 6-phosphogluconate dehydrogenase above trusted (pfam03446). [Energy metabolism, Amino acids and amines].	5.37983e-107
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	5.35727e-124
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.41024e-40
CP025990.1|AUS77111.1|137668_138712_-|3-hydroxyisobutyryl-CoA-hydrolase	gnl|CDD|235533	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional.	1.55672e-179
CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS81362.1|139860_141360_-|methylmalonate-semialdehyde-dehydrogenase-(CoA-acylating)	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0

Protein sequences

>CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3
MHQHLADSAGVARLLVREWLSPAVVDRLAAEFPGGREDVETLTVWLASVHDLLKCSPAFACQVPELANHMASRGLTVRRGIKADPERPRANHAVAGQRVVREWLEEELGFDFLGGAHELASVVGSHHGLPPDDTALHRLDGLEYLLGDRRWQEVRAHILGWSLDHLGGPQALVRFRGVRFSRPALALLTALVIVADWIASNSELFPLYPVGALDRAPGPDDTVTERRVAEAWSKLNLSPRWRAVPFDGDVAGLLRCRFERDRPRDVQIAAVRAAVEQPEPGLLIIEAPMGSGKTEAALLVAEVMAHRAGADGVIVALPTQATTDAMFGRVHTWLHRLDGIPDRASVSLAHGKAHLNDTYSGLVRRGRFASMGDDVERRGSSRRSQDDCEDPVVAHWWLSGRKKSGLAPFVVGTIDQLLFAALKSRHVMLRHLALAGKVVVVDEVHAYDVYMSQYLHRVLEWLGAYRVPVVLLSATLPDHRRAELLHAYDTGRGGDASCVPAGHPGYPVVSVSGGPPPTVLPLPPERTRVALDRLDDGQDTLVTYLRAKLADGGCAVVVHNTVGRVQETARRLSEEFGEDAVTIAHSRFLACDRAEIDRGLLRRFGPPESAPDRPPLHIVVASQVVEQSLDVDFDLMVTDLAPVDLLLQRMGRLHRHTRSRPTAVSSPRCAIVGVEDWAAEPARSHPGSRRVYGEHLLLRAAALVIDRDEIALPHDIAPLVQAGYGDTTLGPNSWQPAMTAAAQAAEETASRRAKDAETYRLGAPSETGALTGWLKAGVGDASEDTARGAAQVRDGAASLEVLVVERDAGGGLRTLPWVPGGGKQLPLDSKVPWDQARVVAACSLRLPLALSTPDVIDEVIDELEDNWFASFQANPLLSGQLVLTLDAERRTRLHDHILTYDRRRGLMHEPA
>CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSLPDPYDLVERPWLLVRDLDGEVTEKSLLDTLTQSETLAGLVGDIPTQQFAHLRLLLAVCHRAFGRGLDDDGWKRLWDEGVPQDQIKDYLEQHRSRFDLFHPAEPFMQVATLRTAKDEVFELNRIVADVPNGHPFFSTRLERDLTLSPAEAARWLVHCHAFDPSGIKSGAVGDSRVKNGKGYPIGTGWSGRLGGVAPEGDTLWRTLLLNLVLPTRENDLPAWEQGQRGPLGKEREPTGPVDLYTWQSRRIRLVGTGDRVTGVLVCNGDPLGPQNQHKHETHTSWRRSETQEKKLKSSTPVYMPLEHSPERVIWRGLTAMLPQTVTSNQRSEASDRLSPGVLDQIARLTSDRRLPRDYPLRLHTIGMTYGSQSSTTAEIVDDAISLHAALLDRELAHLKEVVLGCVRDAEKAAYAVGDLALNLAKACGSREEPNVNGRLGPKDTALELAYAALDPAFRRWLAARLPEDDPIDVKEQWHVAARAEMRAVGSRLIAEAPPTGWTGRLVKDKWLTIPVAERWFTFALNRALPMASPAQPPEKDEE
>CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTGNHSEHPPLRKWVNEQTGRLQQEYVKDRSHAVAGLARLRRAVDTPPGVMPDILDLTYAPFMTQGWHSDQPSAQETAAHHAMTLFAVHQQSLRKHACVPGWGVGRAARALHPQAEISPTDPAARRFATLVTSTDLDELLVHLRGLVKLLRGAEIPLDYGLLADQLVRWHRFEDAPERIRRVWGREFHRVPNTESDTTPPSDNEKTEDAS
>CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSRTIIDLHVIQTVPPSNINRDDTGSPKTAMYGGVRRARVSSQAWKRATRDAFESLLDKENLGVRTKRIVELVAETIGERSPEHADRAQELAKSVLEAAGFKLKAPRKAPEGTPDEADFLVFLSRAQIINLADLAVESAREAGDGKTKIDKSEAKARADRSHSVDVALFGRMVANLPDLNVEAATQVAHALSVHGVTNEYDYYTAVDDHKKADEEEDAGAGMIGTIEFNSSTLYRYATIDVDQLQENLGDVEATRRAVEAFVRAFVSSMPTGKQNTFANRTLPDAVLVVARETQPINLVGAFEEAVTAREQGGRISGSIRRIATHATDIHAAFDETPLRAWSFGVGERVEPLAEIGERVSLDVAVKGAGQLVAERLAP
>CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTALVLRFAAPLQSWGTSSRFTRRNTDLAPSRSGVIGLLASACGVRRADDLGAFTHLRVGVRVDQEGQLERDFQTARSLDGSQVMPLSTRFYLADAVFCVAVEGDAELLDRVRAALRRPAAPLFLGRRSCPPAGRLVEAVIDGDIRTALATVPWLASPAVRRKRASDREVTVDVVLDCPPDTPGSDVVRDVPISFDPRHRQYSWRSVHRDTVTIPNPDHSPPPDEHPHDPMELLGSPS
>CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MHLTRFELNPARRATRHLLASPHRLHGAVMKAFPAAHREPTEDGRVLWRLDQTPKQTLLYIVSPHRPDLTHLVEETGWPATSTWDTRPYGPLLDQLAAGQEWAFRLTANPTRSVRRTSDVDTKRYGHLTVTQQTDWLLGRVERLGFSIPPAVENEPDVTVRGRDRRRFARQGTTVTLTLATYEGRLRVADPALFRRTLTHGIGSAKGYGCGLLTLARVRPT
>CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTEIPGARPVPISHLVRAADRLTFVYLEHCVVHRDANAITSRDERGTFHIPAATLSVLMLGPGTTISHHAVNLLAESGSTVVWVGEHGVRYYAHGRMLTDSSRLLERQAALVSNRTSRLSVARRMYGMRFPGEDVSASTMQQLRGREGARVRRLYREYAARTGIDWDGREYDPLDFAGGSPINQALSAAHTSLYGVVHAVIVSLGLAPGLGFVHTGNRRSFVYDIADLYKAQVTIPVAFEVAATDPDDIGAVTRRAVRDRMKDGQFLRTCVRDIVTLLRDPADGQLGDATDLQLPDVVMLWNEDGPDVPAGVSYGQDDEYDDGVNQDGEAS
>CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVVVVTACPVGLRGHLTRWLLEISPGVFVGGITARVRALLWGRVQEMVKTGRAIMVYNADTEQGLAFEVHGHEWTPVDHEGVQLMLRPAQRKRSAPKQRAGWSTASKRRRYGRGQKSE
>CP025990.1|AUS77109.1|135948_136728_-|enoyl-CoA-hydratase
MNDLHTITLERPADRVALITLNRPKAKNALNLQTMREITDLTARLDADPDVGAIIITGSDTVFAAGADIKEMRDLTFSEVHAQDWLAGWTALADVRTPLIAAVAGYALGGGCELAMMCDLLIAADNAKFGQPEITLGVIPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAEEADRSGLVSRVVPTATLREEALTAATRIAGFSAPAVAMAKEVVNQAFETGLAEGLLFERRVFHSTFATEDQKEGMAAFSEKRAPQFRHR
>CP025990.1|AUS77110.1|136724_137672_-|3-hydroxyisobutyrate-dehydrogenase
MSVAFLGLGNMGGPMAVNLARAGQRVVGYDPVPMARDRVFAAGVTTVEEPGAAVADADVVITMLPGGGHVLDCYQEVLPLAAPGALFLDCSTIDVADARAAAELALVAGHPAVDAPVSGGVVGAEAATLTFMVGGEDTAFTAAEPYLRLMGARAIHCGASGAGQAAKVCNNLILGASMIAVSEAFALGEKLGLTNQALFDVASTASGQCWALTTNCPVPGPVPKSPANRDYAGGFASGLMLKDLGLAMAAAEQTGTTTALGRRAAELYAAFVAQDGPARDFSAIITAIRDGSLDPGTPATAEPVVDDTRNQDGTP
>CP025990.1|AUS77111.1|137668_138712_-|3-hydroxyisobutyryl-CoA-hydrolase
MTDVLRTVRGHLGRLTLNRPKALNALTHDMVRALHAALDDWEHDDTVRTVLVDGAGDRGLCAGGDIRSIHDDARAGGTASLDFWADEYRLNARIARYPKPYVALMDGVVMGGGVGISAHGRHRVVTERSRIAMPEVGIGFIPDVGGTYLLSRAPGQLGTHLALTGAPVSAADALHCGLADHHVPSDRLDDLTEALTQAPAAEAIQAHATPAPASALATDAGWIDHCYTAGTVTDILRRLRDHGGPAAEAAATLDTKSPTALAVTLRALRSAATLPDLEAVLRQEYRTSRAALRSADLVEGVRAQIIDKDRSPRWSPATLAEVDEATVAAYFTADDSDEARLEGVWSR
>CP025990.1|AUS77112.1|138711_139851_-|acyl-CoA-dehydrogenase
MPLTDEQRALRETVADFATEHLEPHAVHWDQTKHFPVDVLRTAAQLGLGGVCVREDVGGSDLTRTDAVLIFEALATGCPSIAGYVSIHNMVARMIDQYGTDQQRHRHLPALCRMDTLGSYCLTEPDAGSDAAALTTRARRDGDHWVLDGVKQFISGAGTSGVYVVLARTGGPGAAGISAFLLEPDTPGLSFGPNEVKMGWNAQPTRQVILDGARVPADALLGGEGGGFRIAMSALDGGRLNIAACSLGGAEAALTKAVRHLTERSAFGGRLADAQALQFRLADMRTELEAARTLLWRAADALDHGEPDATPLCAMAKRFCTDAGFDIANQALQLHGGYGYLTEYGMEKLVRDLRVHQILEGTNEIMRVIVSRWMLREAA
>CP025990.1|AUS81362.1|139860_141360_-|methylmalonate-semialdehyde-dehydrogenase-(CoA-acylating)
MTAELRHFRSGETVPGTSGRFADVHDPSTGAVRARVPLASADEVHATVADAAAAQREWARWNPQRRARVLMRFLELVRAEQDDLARLLSTEHGKTLADSHGDIQRGLEVVEFAVGIPHLLKGEYTESAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAAPAIACGNAFVLKPSERDPSVPLRLAELLIEAGLPPGVFNVVNGDKEAVDALLTHPTIQAVGFVGSSAIAEYVYATAAAHGKRAQCFGGAKNHLVVMPDADLDQAVDALVGAGYGSAGERCMAVSVAVPVGQATADALVERLADRVRALRVGPALDDTADFGPLITAEAVTRVRDYVDLGVSEGATLVVDGRDVTVPDHENGFYLGGCLFDHVRPEMRIHQEEIFGPVLSVVRATDYEDALRLPSEHQYGNGVAIFTRDGDTARDFTSRVNTGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSIRFYTRTKTVTSRWPSGAKEGASFVIPTMH
>CP025990.1|AUS77113.1|142393_143131_-|thioesterase
MTGSRWLPFGVPDRAAPRLFCFPHAGAGAAAFAEWRRLAPPEVQVCPLQPPGRAERMAETAHHDLDALLDDLLDDIGDEFTGRYALYGHSMGALVVFELTRRLRARGATPPAHLVVSGRTAPQRRNPRRVLHTLSTAELVPELRRIGGTPEEVLTEPALLELFLPTLRADFAVNENYRYAEQAPLDVPLTVFGGDDDPRATEEELGEWTAQAGAGCTVRVLPGDHFFLVPHAKELVTTATGELLG
>CP025990.1|AUS77114.1|143127_144204_-|hypothetical-protein
MTSTPTAGEATTTAPTSRPGRIKCVVWDLDDTVWEGVLLEDEQVTVRPEVVAELRRLDQLGVLHSIASRNDPDLAMDRLRAEGLDHYFLHPKITWNPKSSSIERIAADLNIGLDAIAFVDDQPFEREEVRFALPEVTTVDAADITEVLRRDEFHPRFVTDESRHRRAMYQSAAVRDQAEQDHQGTSEEFLATLDLRFTISRAEEADLQRAEELTVRTNQLNSTGRTYSYEELDRLRRSEDHLLLVAALTDRYGDYGKIGLALVERGDEVWHLRMMLMSCRVMARGVGTVLLNHVMRLAGEDGARLRADFVETGRNRMMYVTYAFAGFRELTRDGDSVVFESDLEVVQPMPGYLTVETR
>CP025990.1|AUS77115.1|144200_145352_-|acyl-CoA-dehydrogenase
MTAADTREPAPPTAPDPTLVRDFVDTEIRPRVERYDEDERVPDDLLRRVTELGLWAPFLPEEHGGTGTSTATLARIHEEIGRGCSSLRSLLTVHGMVSWSVWRWGDQGQRDRLLPGLAAGRPLAAFCLTEPEGGSDTSVAATRAEPDGDGWVLTGHKKWITGGQLAGLLLVFAGTGEAMTAFLVPADAPGITVTPLSGVLGTRASMLAEIRFDDVRLGPDAVLGPPGWAAATVMTSALDLGRLSVASGSVGIISAALEACADLTATRPSGDGVLADRQLVRRMLSDMITNRRAARLLCAEAGRLRDTDDPGVITATWVAKYFAATAAARAASDAVQIHGALGCGPRSPVARLYRDAKVMEIIEGSTELQQTAIADHAHREVAP
>CP025990.1|AUS77116.1|145355_145616_-|acyl-carrier-protein
MAQDVRAEVRQFITGRFPQITLDDDQDIFALGFVNSLFAMELVMFVEQRLGVRVPNDELRRENFSSVTAMAALVDRVGTGTEATAG
>CP025990.1|AUS77117.1|145643_146510_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein
MTHVGVVGAGVMGAGVAQNLARHGHPVVLVDSDPHALTRARETIDRDCRMSRFLGGPDLDAEEVLGRITTSEDLAALADTEVVIENITESWDLKKDLYPRLDAAVRADAVFVANTSAIPITRLASLTRRPRRFVGVHFMNPVPMKPAVEIIPGEHTSAEALATVRALLDSIGKKAIPVNDACGFVSNRVLMLTVNEAAFLVHEGVADAATVDEVFRSCFGHPMGPLETADLIGVDTILHSVEVLHDHFADSKYRPCPLLKRMTDAGHHGRKTGRGFYTYDGAAAPANP

Crispr_ID: CP025990_2

• CRISPR_ID: CP025990_2
• CRISPR_location: 133484-134003
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 8 spacers
• Cas_protein_info: cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

Consensus repeat of CP025990_2

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT

spacers of CP025990_2

>2.1|133512|33|CP025990|PILER-CR,CRT
ACTGTCCCGACCGTGGTCTTCACCGGCGTGTGC
>2.2|133573|33|CP025990|PILER-CR,CRT
TAGATGGCCTCCCGCTCATCGCGCGATCCGTCC
>2.3|133634|33|CP025990|PILER-CR,CRT
GACGCGGAGGGAGAAGCGGTGAAGGGGCTAGCA
>2.4|133695|33|CP025990|PILER-CR,CRT
GTGCCGCTGATCCCCCGCAGCGATCGTGATGGA
>2.5|133756|34|CP025990|CRT
GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
>2.6|133818|34|CP025990|CRT
GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
>2.7|133880|34|CP025990|CRT
GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
>2.8|133942|34|CP025990|CRT
GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG

CRISPR arrays and Neighbor proteins around CP025990_2

CRISPR arrays

The CRISPR arrays of CP025990_2

>merge|CP025990|2|133484-134003|PILER-CR,CRT
GGAACAGCCCCGCGTGCACGGGGAGGACACTGTCCCGACCGTGGTCTTCACCGGCGTGTGCGGAACAGCCCCGCATGCGCGGGGAGGACTAGATGGCCTCCCGCTCATCGCGCGATCCGTCCGGAATAGCCCCGCGTGCGCGGGGAGGACGACGCGGAGGGAGAAGCGGTGAAGGGGCTAGCAGGAACAGCCCCGCGTGCGCGGGGAGGACGTGCCGCTGATCCCCCGCAGCGATCGTGATGGAGGAACAGCCCCGCGTGCGCGGGGAGGACGTTGTCCCGCATGGAAATCCGGGACGACGAGTCGGGAACAGCCCCGCGTGCGCGGGGAGGACGTTGTCCCGCATGGAAATCCGGGACGACGAGTCGGGAACAGCCCCGCGTGCGCGGGGAGGACGTTGTCCCGCATGGAAATCCGGGACGACGAGTCGGGAACAGCCCCGCGTGCGCGGGGAGGACGTTGTCCCGCATGGAAATCCGGGACGACGAGTCGGGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|2|2|133484-133755|PILER-CR
GGAACAGCCCCGCGTGCACGGGGAGGAC	ACTGTCCCGACCGTGGTCTTCACCGGCGTGTGC
GGAACAGCCCCGCATGCGCGGGGAGGAC	TAGATGGCCTCCCGCTCATCGCGCGATCCGTCC
GGAATAGCCCCGCGTGCGCGGGGAGGAC	GACGCGGAGGGAGAAGCGGTGAAGGGGCTAGCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTGCCGCTGATCCCCCGCAGCGATCGTGATGGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|2|2|133484-134003|CRT
GGAACAGCCCCGCGTGCACGGGGAGGAC	ACTGTCCCGACCGTGGTCTTCACCGGCGTGTGC
GGAACAGCCCCGCATGCGCGGGGAGGAC	TAGATGGCCTCCCGCTCATCGCGCGATCCGTCC
GGAATAGCCCCGCGTGCGCGGGGAGGAC	GACGCGGAGGGAGAAGCGGTGAAGGGGCTAGCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTGCCGCTGATCCCCCGCAGCGATCGTGATGGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTTGTCCCGCATGGAAATCCGGGACGACGAGTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|378243
CP025990.1|AUS77109.1|135948_136728_-|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|180295
CP025990.1|AUS77115.1|144200_145352_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
CP025990.1|AUS77113.1|142393_143131_-|thioesterase	unknown	unknown	gnl|CDD|225749
CP025990.1|AUS77097.1|122307_123159_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77114.1|143127_144204_-|hypothetical-protein	unknown	unknown	gnl|CDD|273757
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
CP025990.1|AUS77098.1|123194_123536_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS77112.1|138711_139851_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173851
CP025990.1|AUS77110.1|136724_137672_-|3-hydroxyisobutyrate-dehydrogenase	unknown	unknown	gnl|CDD|130753
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
CP025990.1|AUS77111.1|137668_138712_-|3-hydroxyisobutyryl-CoA-hydrolase	unknown	unknown	gnl|CDD|235533
CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS81362.1|139860_141360_-|methylmalonate-semialdehyde-dehydrogenase-(CoA-acylating)	unknown	unknown	gnl|CDD|143404

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	1.6e-30	100.9	0.8
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.4e-30	100.1	0.5
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	1.6e-61	202.9	0.3
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	5.7e-44	144.8	1.4
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	4.5e-115	380.0	0.6
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	5.7e-105	344.9	0.1
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	8.7e-61	200.6	0.0
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.7e-119	394.3	1.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.76798e-34
CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.53404e-75
CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.35097e-73
CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.77767e-40
CP025990.1|AUS77109.1|135948_136728_-|enoyl-CoA-hydratase	gnl|CDD|180295	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional.	3.049e-153
CP025990.1|AUS77115.1|144200_145352_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	8.36634e-92
CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.54305e-166
CP025990.1|AUS77113.1|142393_143131_-|thioesterase	gnl|CDD|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	2.36748e-75
CP025990.1|AUS77097.1|122307_123159_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS77114.1|143127_144204_-|hypothetical-protein	gnl|CDD|273757	TIGR01686, modular_polyketide_synthase, FkbH-like domain. This model describes a domain of a family of proteins of unknown overall function. One of these, however, is a modular polyketide synthase 4800 amino acids in length from Streptomyces avermilitis in which this domain is the C-terminal segment. By contrast, the FkbH protein from Streptomyces hygroscopicus aparently contains only this domain. The remaining members of the family all contain an additional N-terminal domain of between 200 and 275 amino acids which show less than 20% identity to one another. It seems likely then that these proteins are involved in disparate functions, probably the biosynthesis of different natural products. For instance, the FkbH gene is found in a gene cluster believed to be responsible for the biosynthesis of unususal "PKS extender units" in the ascomycin pathway. This domain is composed of two parts, the first of which is a member of subfamily IIIC (TIGR01681) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. All of the characterized enzymes within subfamily III are phosphatases, and all of the active site residues characteristic of HAD-superfamily phosphatases are present in this domain. The C-terminal portion of this domain is unique to this family (by BLAST).	1.31945e-77
CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	3.6946e-126
CP025990.1|AUS77098.1|123194_123536_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS77112.1|138711_139851_-|acyl-CoA-dehydrogenase	gnl|CDD|173851	cd01162, IBD, Isobutyryl-CoA dehydrogenase. Isobutyryl-CoA dehydrogenase (IBD) catalyzes the alpha, beta- dehydrogenation of short branched chain acyl-CoA intermediates in valine catabolism. It is predicted to be a homotetramer.	0
CP025990.1|AUS77110.1|136724_137672_-|3-hydroxyisobutyrate-dehydrogenase	gnl|CDD|130753	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase. 3-hydroxyisobutyrate dehydrogenase is an enzyme that catalyzes the NAD+-dependent oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde of the valine catabolism pathway. In Pseudomonas aeruginosa, 3-hydroxyisobutyrate dehydrogenase (mmsB) is co-induced with methylmalonate-semialdehyde dehydrogenase (mmsA) when grown on medium containing valine as the sole carbon source. The positive transcriptional regulator of this operon (mmsR) is located upstream of these genes and has been identified as a member of the XylS/AraC family of transcriptional regulators. 3-hydroxyisobutyrate dehydrogenase shares high sequence homology to the characterized 3-hydroxyisobutyrate dehydrogenase from rat liver with conservation of proposed NAD+ binding residues at the N-terminus (G-8,10,13,24 and D-31). This enzyme belongs to the 3-hydroxyacid dehydrogenase family, sharing a common evolutionary origin and enzymatic mechanism with 6-phosphogluconate. HIBADH exhibits sequence similarity to the NAD binding domain of 6-phosphogluconate dehydrogenase above trusted (pfam03446). [Energy metabolism, Amino acids and amines].	5.37983e-107
CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	5.35727e-124
CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.41024e-40
CP025990.1|AUS77111.1|137668_138712_-|3-hydroxyisobutyryl-CoA-hydrolase	gnl|CDD|235533	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional.	1.55672e-179
CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS81362.1|139860_141360_-|methylmalonate-semialdehyde-dehydrogenase-(CoA-acylating)	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0

Protein sequences

>CP025990.1|AUS77106.1|130007_132743_-|CRISPR-associated-helicase/endonuclease-Cas3
MHQHLADSAGVARLLVREWLSPAVVDRLAAEFPGGREDVETLTVWLASVHDLLKCSPAFACQVPELANHMASRGLTVRRGIKADPERPRANHAVAGQRVVREWLEEELGFDFLGGAHELASVVGSHHGLPPDDTALHRLDGLEYLLGDRRWQEVRAHILGWSLDHLGGPQALVRFRGVRFSRPALALLTALVIVADWIASNSELFPLYPVGALDRAPGPDDTVTERRVAEAWSKLNLSPRWRAVPFDGDVAGLLRCRFERDRPRDVQIAAVRAAVEQPEPGLLIIEAPMGSGKTEAALLVAEVMAHRAGADGVIVALPTQATTDAMFGRVHTWLHRLDGIPDRASVSLAHGKAHLNDTYSGLVRRGRFASMGDDVERRGSSRRSQDDCEDPVVAHWWLSGRKKSGLAPFVVGTIDQLLFAALKSRHVMLRHLALAGKVVVVDEVHAYDVYMSQYLHRVLEWLGAYRVPVVLLSATLPDHRRAELLHAYDTGRGGDASCVPAGHPGYPVVSVSGGPPPTVLPLPPERTRVALDRLDDGQDTLVTYLRAKLADGGCAVVVHNTVGRVQETARRLSEEFGEDAVTIAHSRFLACDRAEIDRGLLRRFGPPESAPDRPPLHIVVASQVVEQSLDVDFDLMVTDLAPVDLLLQRMGRLHRHTRSRPTAVSSPRCAIVGVEDWAAEPARSHPGSRRVYGEHLLLRAAALVIDRDEIALPHDIAPLVQAGYGDTTLGPNSWQPAMTAAAQAAEETASRRAKDAETYRLGAPSETGALTGWLKAGVGDASEDTARGAAQVRDGAASLEVLVVERDAGGGLRTLPWVPGGGKQLPLDSKVPWDQARVVAACSLRLPLALSTPDVIDEVIDELEDNWFASFQANPLLSGQLVLTLDAERRTRLHDHILTYDRRRGLMHEPA
>CP025990.1|AUS77105.1|128392_130021_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSLPDPYDLVERPWLLVRDLDGEVTEKSLLDTLTQSETLAGLVGDIPTQQFAHLRLLLAVCHRAFGRGLDDDGWKRLWDEGVPQDQIKDYLEQHRSRFDLFHPAEPFMQVATLRTAKDEVFELNRIVADVPNGHPFFSTRLERDLTLSPAEAARWLVHCHAFDPSGIKSGAVGDSRVKNGKGYPIGTGWSGRLGGVAPEGDTLWRTLLLNLVLPTRENDLPAWEQGQRGPLGKEREPTGPVDLYTWQSRRIRLVGTGDRVTGVLVCNGDPLGPQNQHKHETHTSWRRSETQEKKLKSSTPVYMPLEHSPERVIWRGLTAMLPQTVTSNQRSEASDRLSPGVLDQIARLTSDRRLPRDYPLRLHTIGMTYGSQSSTTAEIVDDAISLHAALLDRELAHLKEVVLGCVRDAEKAAYAVGDLALNLAKACGSREEPNVNGRLGPKDTALELAYAALDPAFRRWLAARLPEDDPIDVKEQWHVAARAEMRAVGSRLIAEAPPTGWTGRLVKDKWLTIPVAERWFTFALNRALPMASPAQPPEKDEE
>CP025990.1|AUS77104.1|127763_128396_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTGNHSEHPPLRKWVNEQTGRLQQEYVKDRSHAVAGLARLRRAVDTPPGVMPDILDLTYAPFMTQGWHSDQPSAQETAAHHAMTLFAVHQQSLRKHACVPGWGVGRAARALHPQAEISPTDPAARRFATLVTSTDLDELLVHLRGLVKLLRGAEIPLDYGLLADQLVRWHRFEDAPERIRRVWGREFHRVPNTESDTTPPSDNEKTEDAS
>CP025990.1|AUS77103.1|126630_127767_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSRTIIDLHVIQTVPPSNINRDDTGSPKTAMYGGVRRARVSSQAWKRATRDAFESLLDKENLGVRTKRIVELVAETIGERSPEHADRAQELAKSVLEAAGFKLKAPRKAPEGTPDEADFLVFLSRAQIINLADLAVESAREAGDGKTKIDKSEAKARADRSHSVDVALFGRMVANLPDLNVEAATQVAHALSVHGVTNEYDYYTAVDDHKKADEEEDAGAGMIGTIEFNSSTLYRYATIDVDQLQENLGDVEATRRAVEAFVRAFVSSMPTGKQNTFANRTLPDAVLVVARETQPINLVGAFEEAVTAREQGGRISGSIRRIATHATDIHAAFDETPLRAWSFGVGERVEPLAEIGERVSLDVAVKGAGQLVAERLAP
>CP025990.1|AUS77102.1|125917_126634_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTALVLRFAAPLQSWGTSSRFTRRNTDLAPSRSGVIGLLASACGVRRADDLGAFTHLRVGVRVDQEGQLERDFQTARSLDGSQVMPLSTRFYLADAVFCVAVEGDAELLDRVRAALRRPAAPLFLGRRSCPPAGRLVEAVIDGDIRTALATVPWLASPAVRRKRASDREVTVDVVLDCPPDTPGSDVVRDVPISFDPRHRQYSWRSVHRDTVTIPNPDHSPPPDEHPHDPMELLGSPS
>CP025990.1|AUS77101.1|125252_125918_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MHLTRFELNPARRATRHLLASPHRLHGAVMKAFPAAHREPTEDGRVLWRLDQTPKQTLLYIVSPHRPDLTHLVEETGWPATSTWDTRPYGPLLDQLAAGQEWAFRLTANPTRSVRRTSDVDTKRYGHLTVTQQTDWLLGRVERLGFSIPPAVENEPDVTVRGRDRRRFARQGTTVTLTLATYEGRLRVADPALFRRTLTHGIGSAKGYGCGLLTLARVRPT
>CP025990.1|AUS77100.1|124260_125256_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTEIPGARPVPISHLVRAADRLTFVYLEHCVVHRDANAITSRDERGTFHIPAATLSVLMLGPGTTISHHAVNLLAESGSTVVWVGEHGVRYYAHGRMLTDSSRLLERQAALVSNRTSRLSVARRMYGMRFPGEDVSASTMQQLRGREGARVRRLYREYAARTGIDWDGREYDPLDFAGGSPINQALSAAHTSLYGVVHAVIVSLGLAPGLGFVHTGNRRSFVYDIADLYKAQVTIPVAFEVAATDPDDIGAVTRRAVRDRMKDGQFLRTCVRDIVTLLRDPADGQLGDATDLQLPDVVMLWNEDGPDVPAGVSYGQDDEYDDGVNQDGEAS
>CP025990.1|AUS77099.1|123904_124264_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVVVVTACPVGLRGHLTRWLLEISPGVFVGGITARVRALLWGRVQEMVKTGRAIMVYNADTEQGLAFEVHGHEWTPVDHEGVQLMLRPAQRKRSAPKQRAGWSTASKRRRYGRGQKSE
>CP025990.1|AUS77098.1|123194_123536_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS77097.1|122307_123159_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS77107.1|134076_134928_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS77108.1|134963_135305_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS77109.1|135948_136728_-|enoyl-CoA-hydratase
MNDLHTITLERPADRVALITLNRPKAKNALNLQTMREITDLTARLDADPDVGAIIITGSDTVFAAGADIKEMRDLTFSEVHAQDWLAGWTALADVRTPLIAAVAGYALGGGCELAMMCDLLIAADNAKFGQPEITLGVIPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAEEADRSGLVSRVVPTATLREEALTAATRIAGFSAPAVAMAKEVVNQAFETGLAEGLLFERRVFHSTFATEDQKEGMAAFSEKRAPQFRHR
>CP025990.1|AUS77110.1|136724_137672_-|3-hydroxyisobutyrate-dehydrogenase
MSVAFLGLGNMGGPMAVNLARAGQRVVGYDPVPMARDRVFAAGVTTVEEPGAAVADADVVITMLPGGGHVLDCYQEVLPLAAPGALFLDCSTIDVADARAAAELALVAGHPAVDAPVSGGVVGAEAATLTFMVGGEDTAFTAAEPYLRLMGARAIHCGASGAGQAAKVCNNLILGASMIAVSEAFALGEKLGLTNQALFDVASTASGQCWALTTNCPVPGPVPKSPANRDYAGGFASGLMLKDLGLAMAAAEQTGTTTALGRRAAELYAAFVAQDGPARDFSAIITAIRDGSLDPGTPATAEPVVDDTRNQDGTP
>CP025990.1|AUS77111.1|137668_138712_-|3-hydroxyisobutyryl-CoA-hydrolase
MTDVLRTVRGHLGRLTLNRPKALNALTHDMVRALHAALDDWEHDDTVRTVLVDGAGDRGLCAGGDIRSIHDDARAGGTASLDFWADEYRLNARIARYPKPYVALMDGVVMGGGVGISAHGRHRVVTERSRIAMPEVGIGFIPDVGGTYLLSRAPGQLGTHLALTGAPVSAADALHCGLADHHVPSDRLDDLTEALTQAPAAEAIQAHATPAPASALATDAGWIDHCYTAGTVTDILRRLRDHGGPAAEAAATLDTKSPTALAVTLRALRSAATLPDLEAVLRQEYRTSRAALRSADLVEGVRAQIIDKDRSPRWSPATLAEVDEATVAAYFTADDSDEARLEGVWSR
>CP025990.1|AUS77112.1|138711_139851_-|acyl-CoA-dehydrogenase
MPLTDEQRALRETVADFATEHLEPHAVHWDQTKHFPVDVLRTAAQLGLGGVCVREDVGGSDLTRTDAVLIFEALATGCPSIAGYVSIHNMVARMIDQYGTDQQRHRHLPALCRMDTLGSYCLTEPDAGSDAAALTTRARRDGDHWVLDGVKQFISGAGTSGVYVVLARTGGPGAAGISAFLLEPDTPGLSFGPNEVKMGWNAQPTRQVILDGARVPADALLGGEGGGFRIAMSALDGGRLNIAACSLGGAEAALTKAVRHLTERSAFGGRLADAQALQFRLADMRTELEAARTLLWRAADALDHGEPDATPLCAMAKRFCTDAGFDIANQALQLHGGYGYLTEYGMEKLVRDLRVHQILEGTNEIMRVIVSRWMLREAA
>CP025990.1|AUS81362.1|139860_141360_-|methylmalonate-semialdehyde-dehydrogenase-(CoA-acylating)
MTAELRHFRSGETVPGTSGRFADVHDPSTGAVRARVPLASADEVHATVADAAAAQREWARWNPQRRARVLMRFLELVRAEQDDLARLLSTEHGKTLADSHGDIQRGLEVVEFAVGIPHLLKGEYTESAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAAPAIACGNAFVLKPSERDPSVPLRLAELLIEAGLPPGVFNVVNGDKEAVDALLTHPTIQAVGFVGSSAIAEYVYATAAAHGKRAQCFGGAKNHLVVMPDADLDQAVDALVGAGYGSAGERCMAVSVAVPVGQATADALVERLADRVRALRVGPALDDTADFGPLITAEAVTRVRDYVDLGVSEGATLVVDGRDVTVPDHENGFYLGGCLFDHVRPEMRIHQEEIFGPVLSVVRATDYEDALRLPSEHQYGNGVAIFTRDGDTARDFTSRVNTGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSIRFYTRTKTVTSRWPSGAKEGASFVIPTMH
>CP025990.1|AUS77113.1|142393_143131_-|thioesterase
MTGSRWLPFGVPDRAAPRLFCFPHAGAGAAAFAEWRRLAPPEVQVCPLQPPGRAERMAETAHHDLDALLDDLLDDIGDEFTGRYALYGHSMGALVVFELTRRLRARGATPPAHLVVSGRTAPQRRNPRRVLHTLSTAELVPELRRIGGTPEEVLTEPALLELFLPTLRADFAVNENYRYAEQAPLDVPLTVFGGDDDPRATEEELGEWTAQAGAGCTVRVLPGDHFFLVPHAKELVTTATGELLG
>CP025990.1|AUS77114.1|143127_144204_-|hypothetical-protein
MTSTPTAGEATTTAPTSRPGRIKCVVWDLDDTVWEGVLLEDEQVTVRPEVVAELRRLDQLGVLHSIASRNDPDLAMDRLRAEGLDHYFLHPKITWNPKSSSIERIAADLNIGLDAIAFVDDQPFEREEVRFALPEVTTVDAADITEVLRRDEFHPRFVTDESRHRRAMYQSAAVRDQAEQDHQGTSEEFLATLDLRFTISRAEEADLQRAEELTVRTNQLNSTGRTYSYEELDRLRRSEDHLLLVAALTDRYGDYGKIGLALVERGDEVWHLRMMLMSCRVMARGVGTVLLNHVMRLAGEDGARLRADFVETGRNRMMYVTYAFAGFRELTRDGDSVVFESDLEVVQPMPGYLTVETR
>CP025990.1|AUS77115.1|144200_145352_-|acyl-CoA-dehydrogenase
MTAADTREPAPPTAPDPTLVRDFVDTEIRPRVERYDEDERVPDDLLRRVTELGLWAPFLPEEHGGTGTSTATLARIHEEIGRGCSSLRSLLTVHGMVSWSVWRWGDQGQRDRLLPGLAAGRPLAAFCLTEPEGGSDTSVAATRAEPDGDGWVLTGHKKWITGGQLAGLLLVFAGTGEAMTAFLVPADAPGITVTPLSGVLGTRASMLAEIRFDDVRLGPDAVLGPPGWAAATVMTSALDLGRLSVASGSVGIISAALEACADLTATRPSGDGVLADRQLVRRMLSDMITNRRAARLLCAEAGRLRDTDDPGVITATWVAKYFAATAAARAASDAVQIHGALGCGPRSPVARLYRDAKVMEIIEGSTELQQTAIADHAHREVAP

Crispr_ID: CP025990_4

• CRISPR_ID: CP025990_4
• CRISPR_location: 207411-208352
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 15 spacers

Consensus repeat of CP025990_4

Consensus_repeat	Method
NNNNGGAACAGCCCCGCGTGCGCGGGGACGAC	CRT
GGAACAGCCCCGCGTGCGCGGGGACGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGACGAC	CRISPRCasFinder

spacers of CP025990_4

>4.1|207439|29|CP025990|CRT
GTGGCGGGTTGACGGACGGCCACCACCTG
>4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
TCGCCGCCGCCGCTGGCCCGGACGGCCGGTGGC
>4.3|207557|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GGGCGCCCTCTCCGTGCCCGCGCCTCCTACGAC
>4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
>4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
ATCGCCATCGACCGCCACCAGCAGGACGGGACC
>4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
>4.7|207803|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GTGCCGCTGATCCCCCGCAGTGATCGTGACGGA
>4.8|207864|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GACCGGCTCCAGAGTGCGGCCCGTCGCAGCGAA
>4.9|207925|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
CGACCGTGCTCTCCGACGAACCGGACCCGGACCC
>4.10|207987|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GCAGCGCCTCGGTGTGATCCGCCGTGGCCTGCG
>4.11|208048|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GCTGGTCTCACCCGCCCCACGTGGGGGCGGAAG
>4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GGCCGCATCCGGATCGTGCTGGTCGGCGGGTCC
>4.13|208170|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GATTCGTGTTCCTGGAGAACGTCGCAGCGATCC
>4.14|208231|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
AACGGGGTGCACCCAGTGCACCCAAAGCAGTCC
>4.15|208292|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
ACTTCATCGAAACGATGAAGGAAATGTCTACCC

CRISPR arrays and Neighbor proteins around CP025990_4

CRISPR arrays

The CRISPR arrays of CP025990_4

>merge|CP025990|4|207411-208352|CRT,PILER-CR,CRISPRCasFinder
CTCGGGACCAGCTTCGCGCGGGGACGACGTGGCGGGTTGACGGACGGCCACCACCTGGGAACAGCCCCGCGTGCGCGGGGACGACTCGCCGCCGCCGCTGGCCCGGACGGCCGGTGGCGGAACAGCCCCGCGTGCGCGGGGACGACGGGCGCCCTCTCCGTGCCCGCGCCTCCTACGACGGAACAGCCCCGCGTGCGCGGGGACGACTCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCAGGAACAGCCCCGCGTGCGCGGGGACGACATCGCCATCGACCGCCACCAGCAGGACGGGACCGGAACAGCCCCGCGTGCGCGGGGACGACTCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCAGGAACAGCCCCGCGTGCGCGGGGACGACGTGCCGCTGATCCCCCGCAGTGATCGTGACGGAGGAACAGCCCCGCGTGCGCGGGGACGACGACCGGCTCCAGAGTGCGGCCCGTCGCAGCGAAGGAACAGCCCCGCGTGCGCGGGGACGACCGACCGTGCTCTCCGACGAACCGGACCCGGACCCGGAACAGCCCCGCGTGCGCGGGGACGACGCAGCGCCTCGGTGTGATCCGCCGTGGCCTGCGGGAACAGCCCCGCGTGCGCGGGGACGACGCTGGTCTCACCCGCCCCACGTGGGGGCGGAAGGGAACAGCCCCGCGTGCGCGGGGACGACGGCCGCATCCGGATCGTGCTGGTCGGCGGGTCCGGAACAGCCCCGCGTGCGCGGGGACGACGATTCGTGTTCCTGGAGAACGTCGCAGCGATCCGGAACAGCCCCGCGTGCGCGGGGACGACAACGGGGTGCACCCAGTGCACCCAAAGCAGTCCGGAACAGCCCCGCGTGCGCGGGGACGACACTTCATCGAAACGATGAAGGAAATGTCTACCCGGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|4|4|207411-208352|CRT
CTCGGGACCAGCTTCGCGCGGGGACGAC	GTGGCGGGTTGACGGACGGCCACCACCTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCGCCGCCGCCGCTGGCCCGGACGGCCGGTGGC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GGGCGCCCTCTCCGTGCCCGCGCCTCCTACGAC
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
GGAACAGCCCCGCGTGCGCGGGGACGAC	ATCGCCATCGACCGCCACCAGCAGGACGGGACC
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
GGAACAGCCCCGCGTGCGCGGGGACGAC	GTGCCGCTGATCCCCCGCAGTGATCGTGACGGA
GGAACAGCCCCGCGTGCGCGGGGACGAC	GACCGGCTCCAGAGTGCGGCCCGTCGCAGCGAA
GGAACAGCCCCGCGTGCGCGGGGACGAC	CGACCGTGCTCTCCGACGAACCGGACCCGGACCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCAGCGCCTCGGTGTGATCCGCCGTGGCCTGCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCTGGTCTCACCCGCCCCACGTGGGGGCGGAAG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GGCCGCATCCGGATCGTGCTGGTCGGCGGGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GATTCGTGTTCCTGGAGAACGTCGCAGCGATCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	AACGGGGTGCACCCAGTGCACCCAAAGCAGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	ACTTCATCGAAACGATGAAGGAAATGTCTACCC
GGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|4|4|207468-208352|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCGCCGCCGCCGCTGGCCCGGACGGCCGGTGGC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GGGCGCCCTCTCCGTGCCCGCGCCTCCTACGAC
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
GGAACAGCCCCGCGTGCGCGGGGACGAC	ATCGCCATCGACCGCCACCAGCAGGACGGGACC
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
GGAACAGCCCCGCGTGCGCGGGGACGAC	GTGCCGCTGATCCCCCGCAGTGATCGTGACGGA
GGAACAGCCCCGCGTGCGCGGGGACGAC	GACCGGCTCCAGAGTGCGGCCCGTCGCAGCGAA
GGAACAGCCCCGCGTGCGCGGGGACGAC	CGACCGTGCTCTCCGACGAACCGGACCCGGACCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCAGCGCCTCGGTGTGATCCGCCGTGGCCTGCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCTGGTCTCACCCGCCCCACGTGGGGGCGGAAG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GGCCGCATCCGGATCGTGCTGGTCGGCGGGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GATTCGTGTTCCTGGAGAACGTCGCAGCGATCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	AACGGGGTGCACCCAGTGCACCCAAAGCAGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	ACTTCATCGAAACGATGAAGGAAATGTCTACCC
GGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|4|3|207468-208352|CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCGCCGCCGCCGCTGGCCCGGACGGCCGGTGGC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GGGCGCCCTCTCCGTGCCCGCGCCTCCTACGAC
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
GGAACAGCCCCGCGTGCGCGGGGACGAC	ATCGCCATCGACCGCCACCAGCAGGACGGGACC
GGAACAGCCCCGCGTGCGCGGGGACGAC	TCCGCCGGGCCGAGCTGGCCGCCCGTCCAAGTCA
GGAACAGCCCCGCGTGCGCGGGGACGAC	GTGCCGCTGATCCCCCGCAGTGATCGTGACGGA
GGAACAGCCCCGCGTGCGCGGGGACGAC	GACCGGCTCCAGAGTGCGGCCCGTCGCAGCGAA
GGAACAGCCCCGCGTGCGCGGGGACGAC	CGACCGTGCTCTCCGACGAACCGGACCCGGACCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCAGCGCCTCGGTGTGATCCGCCGTGGCCTGCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCTGGTCTCACCCGCCCCACGTGGGGGCGGAAG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GGCCGCATCCGGATCGTGCTGGTCGGCGGGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	GATTCGTGTTCCTGGAGAACGTCGCAGCGATCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	AACGGGGTGCACCCAGTGCACCCAAAGCAGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	ACTTCATCGAAACGATGAAGGAAATGTCTACCC
GGAACAGCCCCGCGTGCGCGGGGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77127.1|210512_211202_+|hypothetical-protein	unknown	unknown	gnl|CDD|371490
CP025990.1|AUS77126.1|209082_210306_-|hypothetical-protein	unknown	unknown	gnl|CDD|226156
CP025990.1|AUS81364.1|203863_205012_+|phospho-2-dehydro-3-deoxyheptonate-aldolase	unknown	unknown	gnl|CDD|366662
CP025990.1|AUS77124.1|202448_203792_+|hypothetical-protein	unknown	unknown	gnl|CDD|275237
CP025990.1|AUS81363.1|146506_150076_-|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|238429
CP025990.1|AUS77122.1|183894_190167_-|polyketide-synthase	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS77121.1|172563_183870_-|beta-ketoacyl-synthase	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS77120.1|166167_172509_-|modular-polyketide-synthase	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS77132.1|215352_218211_-|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226415
CP025990.1|AUS77131.1|214564_214855_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77133.1|218255_220778_-|hypothetical-protein	unknown	unknown	gnl|CDD|379062
CP025990.1|AUS77128.1|211595_212591_-|O-succinylbenzoate-synthase	unknown	unknown	gnl|CDD|235084
CP025990.1|AUS77123.1|190183_202522_-|polyketide-synthase	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS77130.1|213442_214330_-|transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS77125.1|205027_207217_-|hypothetical-protein	unknown	unknown	gnl|CDD|276938
CP025990.1|AUS77134.1|220774_223555_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|379062
CP025990.1|AUS77119.1|159523_166135_-|hypothetical-protein	unknown	unknown	gnl|CDD|238429
CP025990.1|AUS77118.1|150087_159408_-|polyketide-synthase	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS77129.1|212590_212893_-|hypothetical-protein	unknown	unknown	gnl|CDD|237600
CP025990.1|AUS81365.1|213185_213416_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77127.1|210512_211202_+|hypothetical-protein	gnl|CDD|371490	pfam11361, DUF3159, Protein of unknown function (DUF3159). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed. Currently this family of proteins has no known function.	2.891e-06
CP025990.1|AUS77126.1|209082_210306_-|hypothetical-protein	gnl|CDD|226156	COG3629, DnrI, DNA-binding transcriptional activator of the SARP family [Signal transduction mechanisms].	3.1885e-15
CP025990.1|AUS81364.1|203863_205012_+|phospho-2-dehydro-3-deoxyheptonate-aldolase	gnl|CDD|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	1.93351e-140
CP025990.1|AUS77124.1|202448_203792_+|hypothetical-protein	gnl|CDD|275237	TIGR04444, hypothetical_protein_ThecoDRAFT_3161, chorismatase, FkbO/Hyg5 family. Members of this include two chemically distinct enzymes that cleave pyruvate from chorismate. FkbO and RapK convert chorismate to pyruvate plus (4R,5R)-4,5-dihydroxycyclohexa-1,5-dienecarboxylic acid (DCDC). HygB and Bra8 convert chorismate to pyruvate, water, and 3-hydroxybenzoate. These two enzymes are closely related, and lack homology to chorismate lyase, EC 4.1.3.40, which converts chorismate to pyruvate plus 4-hydroxybenzoate.	3.16248e-107
CP025990.1|AUS81363.1|146506_150076_-|short-chain-dehydrogenase	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	7.56654e-164
CP025990.1|AUS77122.1|183894_190167_-|polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS77121.1|172563_183870_-|beta-ketoacyl-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS77120.1|166167_172509_-|modular-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS77132.1|215352_218211_-|LuxR-family-transcriptional-regulator	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.46896e-19
CP025990.1|AUS77133.1|218255_220778_-|hypothetical-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.01467e-11
CP025990.1|AUS77128.1|211595_212591_-|O-succinylbenzoate-synthase	gnl|CDD|235084	PRK02901, PRK02901, O-succinylbenzoate synthase; Provisional.	2.3218e-153
CP025990.1|AUS77123.1|190183_202522_-|polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS77130.1|213442_214330_-|transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.91888e-09
CP025990.1|AUS77125.1|205027_207217_-|hypothetical-protein	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	2.31155e-46
CP025990.1|AUS77134.1|220774_223555_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	5.2454e-14
CP025990.1|AUS77119.1|159523_166135_-|hypothetical-protein	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	2.28712e-168
CP025990.1|AUS77118.1|150087_159408_-|polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS77129.1|212590_212893_-|hypothetical-protein	gnl|CDD|237600	PRK14072, PRK14072, diphosphate--fructose-6-phosphate 1-phosphotransferase.	0.0064681
CP025990.1|AUS81365.1|213185_213416_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	7.19878e-19

Protein sequences

>CP025990.1|AUS77125.1|205027_207217_-|hypothetical-protein
MEFGILGPLSVSRGGAPLPVSGVHQRAVLAYLLLHGNEVIPTSRLLRTMWGDNAPRTARKMLQNAVSGLRGLLAAEEDAPILLTHAPGYLLQVDPVRVDRHAFTDLAERGRAALRAGDPAGAAESLRLALGLWRGDPLADLVELGFDWPELNVLREARASAVEDRFEAELARGRHQDVVGELELAVTADPLRERLCGLLMLAAYRCGRQHEALAAYRSLRTRLVAELGVEPGETLRTLERDILNQRPELAAPTTPGAAAGVPGPTVVPGAAPSPALAPAPRHNGGASATRLGAPAPPEPARPAPGPIPENGAVAEQRALTVVMVMTTAEHAATVEGFVCQQIRHHGGQPAPGPGSSWCGYFGASGRQPDHADRALAAAGAIARRSVVDFHPAEVRVAVHSGEAVVTRLVDGDTAVPKVAAVVLDSCRRLAAAATPGRVVLNTAPPEGPVGHGPFAARPRPTGAPAELPSSWHGPTPFVGRSFELDLLQRTAARTHATGRPAMVTLLGAPGVGKTRLVSELVDQLRDGTLNTTRVLRTRVRPGHGDAGTVLSELVRDQPGGGVEALRGLASRQPALVVVDDAHHADDDLLAALAALVDTPDPLPLMIVTTARDAFSRRVSENATGPNSLSFVLDRLTDNAVTRLLDVVLNPRRRQSHLGPSQPSAATGEWRELLGEIRGCPLRALEYAARFNAAGDDQAAHREGMAGFARFNPRGAEAGVPVPAVAAIPG
>CP025990.1|AUS81364.1|203863_205012_+|phospho-2-dehydro-3-deoxyheptonate-aldolase
MDWHGVPALQQLDWRWDESHTPVLRALEAAEPLVTGAEVRELSTRLAAVCSGDGVLVQAGDCAESFHAASDPRTDAVVAVLDRLAAGFGGGRPVLRVGRIGGQFAKPRSRSEEVVDGVPLPPFRGHLVNSEVADARARRPDPRRMLTGYRLAASAHRRLAAHRASRPDGWGPWSSHEALVLDYESAFLRPDDTGELVLGSTHFPWVGERTRQLDHGQVRLVASAGNPVACKLGPGATGEDVVRLCEVLNPDRTPGRLTFVVRMGVPAITSALPPLLRAVRAVHHPVVWVSDPMHANTVAAPGGRKTRFLTAMVEEVGWFTRIVRDHGEHAGGLHLEVAAEEVTECVGGPVPDVEALDARYETLCDPRLSPAQAAELVARAGF
>CP025990.1|AUS77124.1|202448_203792_+|hypothetical-protein
MRSGMSRAWSRTSSWTGRINSVLSMSPHFAHWGRGRPARGAGRDRRPRYERRPSARCGRSPPHGHPPGIRAAAHQPAVTDRWKSGTAPGLAWFLASGPTAVGTPLLGWSMTRSPVQPVGALAPLLLAPDSDSASAEDGPVLGVNRYLDVASAPADAAHPGMTVPLAAPTDEVAEVWPADGPIRSGDHGGIRYAHSDRFLFCSARLPGSGSGAREVGRMYRELFALLARLDYPRLVRVWNHIAGINDRTGTGEETYRDFCVGRSLALEELGMLSDMPATTVIGAAAGGVELSLIATRGVDPVNVENPRQVPAYHYPSRYGRRAPNFARATYLPRHGDPAARGSVLVSGTASIIGHETRHVGDVRAQCRTALGNVELLVGPENLGRHGVDHAYGLADLRAAKVYVRHAEDLPAVREVCAELLPADGRVAYLRADICRADLLVEVEGVAT
>CP025990.1|AUS77123.1|190183_202522_-|polyketide-synthase
MLRTELIRPVHELVRDHARDIPERTAYSDARRSVSYAELSARTGRLAGHLAALGVAPGERVAFVLGNGVSLVESYLATARASAVGVPVNPLSSDDELAHLLADSGAVAVITDPARIARLTRVAPALTTVLADEVDPVDWDGPRFEDLATSPAPEPARDDLGVDDWAFMLYTSGTTGRPKGVRSSTRNSLWTIAACYAPILGLSGEDRVLWPLPLHHCLGHHLGTLGVLAVGASAHVTSGFAAEEVLAGLAAGEFSVLVGVPAMYQELLRAADADGIVAPGLRLCLTAGAVGGAELPARVEARFGAPLIDSYGTTETCGPITTNWPGGTRVPGSCGLPVPGLSVRLVDPGTRTDVPVGEDGEVWVRGPNVMAGYHRDPGATADALPGGWYRTGDLARRDDHGYLTVTGRISELIIRGGENIHPAEVEQVLLGAPGVLDAAVGPAPDPRLGEVPVAYLVARDDLDPEEVLRVCREKLAGFRVPTQLRALDALPRTAAGKVTRHLLAERPWRLLAEVPTTAEEPAPGADEGRADGLRASLLPLSRRERHRRLLGLVREGTAAALGVDRADVTDDRPFGELGLTSLTALLVRDAVVRRAGVPLPATVVFDHPTPDSVARLLRDRLFGTTTTVTAGGTSSRPEPRRRAAPAEPDDDPVVIVGMGCRLPGGVDDPADLWRLVVDGVDATGEFPTTRGWPLHRLHDPDPDRPGRSITTRGGFRADVEDFDAEHFGISPREALAMDPQQRLLLEVAWRTLENAGIAPDSLRDREVGVFTGVMRHEYGAGIDPLPPELEGYLDVGKLGSVASGRIAYTLGLRGPALTVDTACSSSLVALHLAARSLRAGECELALAGAATVISTPQLFVEFSRQRGLSPDGRCRSFSADADGTGWAEGAGLLLLQRLSAARRDGREVLAVLRGSAVNSDGASHGLTVPNGQAQRAVIRRALADAGLEPSEVDAVEAHGTGTVLGDPIEANALADTYGADRDHPLWLGSLKSNLGHTQAAAGVAGVIKVVLALRAGRLPRTLHVDRPSPHVDWATSGLALLTEEQPWPDHGRPRRAGVSSFGISGTNAHVVLEQAPAPPEAAPTTRTPPPLVPLVLSGRDDQALRAQVDRLTDHLRGSGGADASDLGFSLAAGRATLDHRGVLLLGADEDPARALRDWSDRAVTTTVGGGGDGVVLVFPGQGSQWAGMGTRLLAVSAPFRAELAACDDALRPHLGYSALDVLTGAEGAPGLDTVDVVQPVLWAVMVALGRLWTSLGVRPDAVIGHSQGELAALCVAGGLDLGDAARIIALRARALREIAGDGGMVSVPLSAADTERRLPPGTVVAASNGPRSTVVSGDGAALDRLVASCADDGIRARRIPVDYASHSPRMEALRDRLVDLAADIRPRACDTRFYSTVTGTRVDTADLGPEYWFRNLRDPVRFQDAVEAALADGHRVFVESSPHPVLTVGLTDILDEREATGVVTGSLRRDHDDLTPLLTAAAQLWTAGVDVDWTSWFQGSGARRVPLPGYAFRRQRFWLPPAGGGTGDLGSAGITAADHPLLGASVDLPDATVHTALISLTTHPWLADHAVRGTALVPGTAVLDLVATVAAGHGCDRIEELTLTAPVAVELDVPVTLRLVVDQPDADGRRPVALHARAGDRPWTTHATGAVVAAGPGPAPAAWSTGAAEPVDLDGAYDRLADRGYEYGPLFRGLRALWRTGTGPGAELHAEVELPEDTGGDFTCHPALLDAVLQAIGASGADVGGAGTPLPFGFTGVELRAPTGRALRARLRVLDATTVEVVAVDHAGRLVARVEALTLRSPAAAAPAPHRLDHVPVDHPAATDVRVAALDADLTAPHPVPDPVPVEDAEFVLVRAPAGDPGTATRAALALAKDWIGRDATLVVLTRGGGPVTGLFRAAATEHPGAFATVDGDPGPAWPAVFGALRAGESDLAVRDGVVTAARLRPASAPPPTDPPPLPVPDGPWRLAIGGTGSLDDLAAVPAPPAPLRPGQVRIAVRAAGVNFRDVLLALGVVAVTDDVLGGEAAGVVVETAADVTHLHPGDRVFGVVDGAFAPRVVADARMLAPIPAGWSFADAAGVPIAQLTAHYGLFDVAGLQPGQTVLVHAGTGGVGMAAIALARRHGARVLATASPGKWSVLRDLGIPEDHIASSRDTGFEERFRAVTGGRGVDVVLNSLTGEFVDAGLRLTAPGGRFVELGKTDIRDPGTAPGLTYRAFDLLTDAGPERIGEMLAALTTDGPGPLPTRAWDVRHARAALRVMAAGRHTGKNVLTVPAPVDPGGTALITGGTGVLGGLVARHLAARHGIRRLVLLSRGGHAAPELLADLAEAGAEVRVVACDAADRAALRALLATVDDLGVVVHAAGVLADATVANTDPDTLPAVLDPKIAAARHLHELTAHTDLAAFVLFSSIAGTLGGAGQAGYAAANAALDALAVERRAAGLPAVSIAWGMWAEVSGMTGHLTDRDRERLRRGGVLPMDTDAALALFDAALDSPDPCVVAAALDPRSARPLPPAMRVLVRGRPVDRPARGGGARLGDLPAADRPAAALALVRAEAAAVLGHPGPAAVVPDRAFSEQGFDSLTGVELRNRLQAATGLRMSTTAAFDHPTPAALATHLLTALDGTPAPARTATRAAPAAEDEPVAIIGMSCRFPGGIASPEDLWRVVDDEVDVVGPFPTDRGWDLAALFDEDPDRTGTSYVRAGAFLDDVAGFDAAFFGISPREATAMDPQQRLLLELAWEVFEDAGIDPTALRGSPVAVYAGQIHHDYVGRLRTVPGELEGYLGHGTAGSVASGRIAYTFGLEGPAVTVDTACSSSLVALHLAVGALRSGECDLALAGGASVMSSPTPFVEFSRQRGLAPDGRCKPFAAAADGTGWSEGAGLLLVERLSDARRHGHPVLAVVRGTSVNQDGASNGLTAPNGPAQQRVIRQALASAGLAARDVHLVEAHGTGTRLGDPIEAEALLATYGRDRDTPLWLGSVKSNLGHSQAAAGVAGLIKVVQAMRHARMPRTLHVDRPTGHVDWTAGAVELLTEARDWTGEAPRRGAVSSFGVSGTNAHVILEQAPDEPGRPDPAPDIGPSTAPPLLLSARSGAALTEQAGRLARLLTDDDVDVTDVAHGLLTRRAALDRRAVVLGADRDGLHAGLRALASSRPTPSVVTGVVDPDARTVLVFPGQGAQWPGMARDLLAESPVFAARIADCAAALRRHADLDLEAALRTGAGLDRVDVLQPALFAMMVSLAAVWEEHGVRPDAVIGHSQGEIAAACVAGALSLDDAARVVAVRARALRDLAGTGGMLSVGLSAADAADHLAPHAGRVSVAATNGPLATVLAGPPEDLDALAAALHSAGVRARRIAVDYASHSPAVDTLRDTLVRDLADIHPGHPTVPMRSTVSGDWVRAGELTADHWFRNLREPVRYLPATEALLAGGHRTFVEVSPHPVLLPATGDIAEAAGVPVGLVATLRRDHGGHRQVLTAVAEAHVRGVPVDWSTVIARRTARPVALPTYPFQHRRYWIDEPDTPQERDDDFWTAVHDGDTETLRTRLGLADVEDLHALDRLLPALATWHTPAGADLCHRVEWRPLPHRPATTPPEGRWLVLTPSSVEVPAGIPAGFEVRTATDTSRAGLARLLADGETAGVVSLLSLADEGTATGGLFATVHLVQALPKGVPLWIVTRGAVSAAPGDDVPNPGQAAQWGLGRVLAAERPDSWGGLVDVVDLDALTWLPTAVAGDEDELALRAGRAWTRRIRPAPAPPTPGRWRPAGTAVVTGGEGTTGRLVATWLAALGAPRVLLLTDPATPPPEDLPSAVHPVPCDPADEDALRAALADETPRVVVHTAGVLDDAMLTDLTDAQLTRVLRARVTAATALDRVSRDHEVDAFVLFSSVGGTLGASGQGGYAPGHAVLDALAARRRAQGLPATSVAWGHWASDGDHGRRPGVRDLDPERALATLRRILDAPADTLVADLDWAVVAGPTPPPLLRDLLPAAEDTAGPADLLARLRAADPAARHRIVRALVLDTTAAVLQHGELDSVDPGRGFREQGFDSLASVRLRDGLNTATGLRLPATAAFDHPTPDALTRHVLAELDLDDAPGAGGADIESASDEELIALLDAEFGIS
>CP025990.1|AUS77122.1|183894_190167_-|polyketide-synthase
MTDDDRMRRLLNKVTVELRQARAQLAARPEDPGREPVAIVAASCRYPGGADSPEALWDLVAQGRDATGDFPTDRHWDIEGLHAEDPGTRGGITTRRGGFLADVAGFDADLFGISPREALAMDPQQRLLLELTWEALERAGIAPDGLRGERVGVYTGISATEYGARHAGVPHDLEGHLGTGKAGSVVSGRLSFAYGFEGPSLTVDTACSSSLVALHLATRALRAGECRLAVAAGVAVIAEPAVFVEFSRQRGLAPDGRCKAFSAAADGAGFSEGAGVLLLAPLSEARRAGLPVLGLVRGSAVNSDGASSGLTTPNGPAQQRVIRAALADAGLRPSDVDLVEAHGTGTRLGDPIEARALLATYGQDRDTPVWLGSVKSNLGHAQGAAGMAGVIKALGALRHGALPRTLHADTPTPEVDWTAGRVELLTQARPWPAGPGPRRAAVSGFGMSGTNAHVVLEAAPEPEPQPEPEPAPVSPPVVATGDPTGGPTPPAVPWLLSAPNPPALLAQARTLADFLTAHPELRPADVGLTLATRRALLPHRVVVTGGLDELRSLPADAGEHGHGGGIAFTFTGQGAQHPGMGRELRAAHPRYAEAFDEVCAELDRHLGAATPLADLVLTGADDGRLDDTGHAQAALFAVEVALFRLLESWGVRPDVLIGHSVGELAAAHVAGAWDLPDACRVVAARARLMAALPPGGAMVAVAAPEAEVSVEVAGTAVSVAAVNGPASVVISGEATEVRALAARWAGRGTRTRELRVSHAFHSALVEPVLDEFRAVVAGTTAREPSIPVLSNRTAAPLTADQVASPDYWADHARGTVRFADCVAAAERGGTTTFVELGPGGVLSAMVTDTLRRPGGAAIALLRHDTPETRSVAAGVGRLVTRGHDVTLTPLFTDLGATPVELPTYSFQHTPYWLGAPAAATGAAALGQDTTGHPLAGAAVDLPDGGVLLTGRLSRADQPWLADHRVLDRVLVPGTALVDLAVRAGDELGASTLEEFVVHRPLELPDRGAVRIRVVATPGEPATVSVLARPDHPGGTWTEHASGTLTDGHAEPDPLTDWPPSGGRALSTGDVYTSLRAVGVDYGPGFRGLRAAWRRDDVVFAEVTLPAPAEPDGFAVHPALLDAALHTLRLTGFLPADAAFVPFSFAGMRVHATGARTLRVRVTHLGGQAVRLVLADAGGAPVAEIAALTVRRLGGDPTTRDPAVLDHLLRPGWTPTSGTEEDPARWAPLGEDRFGLGPGEGTDAQVRIWSPPTGDVRTATTAALTTLRDWLATDDGTRLLVLTTGAVSTAPGEDVPDLAAAAVHGLVRSAQSEHPGRLVLVDVDTTTATTRDLPAALRRALATGEPQIAVREGRPLAARLTRFTSDGVLAPPPGEPAWRLGTSGTGTVENLRIDPCPDVLDTPLPAGRVRIDVRAAGVNFRDVFTILGLFPSVTGLLGGEAAGVVREVGPGVTDLRPGDPVTGLVFGGFGPVAVADRRLLTRFPDGWTFEQAAGMPLVFLTAYHALVDLADLAPGESVLVHAAAGGVGMAATQLAHHLGATVHGTAHPRKWDALRGNGIAEERIASSRTLEFEDAFADGVDVVLNSLSGEFVDASLRLLRPGGRFLEMGKVDIRDDATIARDHPGVRYRDFDVLDAGPDHIQRMFTALLDLFDRGALAPLPVTTWDVHRAREAFRHVREGHHTGKVVLTLPRRPDPDGTVLVTGGTGDLGGLLARHLVDAHGVRHLLLLSRRGPDAPGAAALTEDLTSAGARVRVLACDVGDRDALAEAIASVPAAHPLTGVVHTAAVVDDAVIGSLTPDQLDRVLRPKADAALHLHELTSDLALFALFSSAAGVLGGPGQGNYAAANAVLDGLAAHRHAHGLPATSLAWGLWEQDRGITAGLSATDRARMRRDGLLPLGRSEGLDLFDHAVTTAEPRCLPLRLDLATVAGRPVPPPLARLVRPTRRAASEGDTAPAALADRLAALPTARAGAAVLDVVREHTASVLGHGETTDIRPDQGFGDLGFDSLTAVELRNRLVRATGVRLTATAVFDHPTPEALADHLLDTLRPPTADPGTDPGTATPPTEDAESELDSLDPDELIRRALAGAGD
>CP025990.1|AUS77121.1|172563_183870_-|beta-ketoacyl-synthase
MPPGWTRAIGPPPHPDLACCWTARPLRRRRGMAEADERLVEALRASLKENERLTRRVRERDETEAEPIAIIGAACRFPGGVDSPEDLWRLLAEGRDVAGPFPTDRGWDLDHLFDSDPAASGRTYVDRGGFLADAALFDAALFDISPREALAMDPQQRVLLETAWRAVEHARIDPRSLRGTPTGVFVGVSGQDYDRDARHGVPEVEGYLLAGNTTSVASGRLAYTLGLEGPALSVDTACSSSLVALHLAARSLRSGESRLALVGGATVLTSPHLFVEFARQRGLAPDGRCKSFADAADGTAWSEGAGLLLVERLSDALRHGRRILAVVRATAVNSDGASHGLTAPNGPAQQRMIRTALAAAGLEPADVDAVEAHGTGTALGDPIEAQALLATYGQRRDTPLLLGSVKSNLGHTQAAAGVAGVLRTALALGRGVLPRTLHVDRPTSHVDWTSGAVTLTTEDTPWPEHDRPRRAAVSSFGISGTNAHVILEQAPPPPPNAAPGRVRGPLTPLVLSARTPEAVPVQARNIAEVLRDGAQPADLGHSLATTRASLDHRAVVLGRDRADLLAGLAEVTAPRPTRPGRLAVLFGGQGTQRPGLGRRLHAAYPAFAAALDEVCAALEPELGFPVRDLVLGETSPADAARLDRTGHAQPALFAVEAALHAVVSSWGVRAEVVAGHSVGELTAAYVAGVWDLPDACRVVAARARLMDALPDGGAMAALNTDRGTAEALRVDGVEIAAVNGPEAVVVSGPAHAVDAAVRTAAARGIRATRLRVSHAFHSALVEPALADLRAALDGVTFHEPGLTGLSNVTGGTAERWTDPDYWVEHARATVLFGDLVAALPGLGVTAVLELGADSTLTGLTGLVLGDAVPAVPALRRDHDEAESLLRALADLHVAGVPVAWREFFEDARTLDLPGYPFHRRHYWLTAPGPRADGTGLGVRAAGHPLLGGVVDVPGSDEVLFTGRLCPDTPPWLADHRVLGRTVVPGAALVDLALRVGDEVGHPQVTELTSLAPLVLDGPLVLRVVVAPADATGDRPFTVHARPESGDEWTRHATGTLGVAGPPPTPAPPPAAPDPVDTAALYAELAERGLDYGPSFQGLRAARRDGTTVHASVEVPGPAEGFGPHPAVLDSTLHALHPSGLLPDHDGAPLVPYSWRGVRAHHPGTTAARATITRLDDSSVSLLLTDGTDRPLLTVDRLTLRPATPPPAATSGGHLHATDWVEVAPTSTAPAAATEWAPSGDAAEELPTLLDLLDRPDRVVVRTRGAVDLGDEPVVPEAAGLWGLVRSAQAEHPGRLVLLDADDSAEAVRLALATGEPQVAVRDGRVFAPRLTPVAEDTAGRRSPTAHGTVLVTGGTGGVGSHVVRHLVHQWGATRVVVAARSDTGVADLVADCGEAVRFVPCDVSNPDELAGLLATLADTLAGVVHAAGVLDDGVLTSLTPDRLRRVAAPKAGAARTLDQLTRDLDLDFLVAFTSAAGVLGAPGQAAYAAANAEVDALMARRRRQGLPGQTVAWGLWADTGMARTLTASERRRLVTTGFPPLDPPRALELLDLAMTRAEPSLVALDLDPGQLARHPDPPALLTDLLPAARPRTAEPPPPPSDPLALVRAHLAAVLGHDDPRRVDAHRGLRELGVDSLAAVELRNRLSAATGRPLPATLAFDHPTAERLAAFLAADGHPEETPAAAPTAGSSDDPIAIVGLACRYPGGVRGPDDLWDLLTAEVDAIGPFPTDRGWDLHRVLGSDPTRPGTSSVGEGGFLDDAALFDAGLFGISPREAMAMDPQQRQLLETSWEALEHAGIDPRSARGSRTGVFTGIMYHDYGPGFADAPPEVEGLLGAGTTGSVASGRVAHVLGLEGPALTVDTACSSSLVAVHLAARSLRTGESTLALAGGATVMSTPAAFVEFSRQGGLAADGRCKSFSEDADGTAWSEGVGVLVLERLSDARRHGRHVLGLLRGSAVNHDGAASGLTAPNGPAQRRVIRAALADAGLTARDVDVVEAHGTGTALGDPIEAHALLTTYGADREAPLLLGTVKSNLGHTQAAAGVAGVIKALLAMRHGTVPRTLHVTTPTSRVDWSAGAVRLATETRPWPDTPGPRRAAVSSFGFSGTNAHVVLEAPPPTPAREEPGRTENPVPLLLSGRTPSALRAQAARLAELVDTRPEVPLGALARSLAHTRARLDHRAVVLADDRPAASAALGALARGETNPRLVSGVVPVHQLAVVFGGQGSQRIGMGRELHDRFPVYADTFDRVCAALDAELAADRPLAEVVFGADADALDRTGWAQPALFAVEAALHALVSSWGVRAEVVAGHSVGELTAAYVAGVWDLPDACRVVAARARLMDALPDGGAMVAVAAGRGEVEELLVPGAGVGAVNGPTSVVVSGESGAVATVAEAAEARGLRTRALRVSHAFHSHLVEPVLADFARVLREVRFAAPTLPGLSNVTGGPADRWTDPDYWVDHVRAPVLFADDLAALEASGVDAVLELGADATLTGLAATVLAEPGRAVAALRRDRPEAASLLAAVGELYCAGVPVEWDDLFGAGDWVDLPTYPFDRERFWLTGTSRPAADTSGLGVTGTDHPLLAAAVEVPGTGAVVLTGALSTTSRPWLADHRVLGQVVVPGAAIVEMAVRAGDEVGRGTVDELVTTAPLVLSDHEPTQLRLVVARENDQGHRPFTLHARLESEGEWRVHATGALSAGPDHAPAPDADLARRAPVSAGTDGVYETFAAAGLDYGPAFRGLRATRRDGDHALASVELPEPEHAPATAFGVHPALLDAALHAVGAAQLLPAGDGGPLLPYSWRGVTPHASGATAVRVRVSRLSDNTVSLRAVDAEGVPVLTVDRLMLRAASPEGVRAAAATGGALHEVAWRAVERPTEGTVGWSWDRVTGADALRDLDTAPDVLFWEAASGTGPVTALDLVQTFLAADRFTRTRLVVLTRDAVTADPDEGLAEAPVDPAAAGVWGLLRSAQSENPGRILLVDTDRPLSVNAPEVRGAVAAGEPQLALRSGRLWAPRMRPVDGGLSLPGTPWTVGTEPGGSLDGVRVDTARREALGLGEIRVSVRASGVNFRDVMTVLGMYPGEPLPLGLEAAGVVTEVGRGVDGFAVGDRVMGLCEGGFASEVVVDHRMWSRFPGSWSFAEAATVPVTFLTAWYGLRDLGRLVEGESVLVHSAAGGVGMAAVQLAREWGAVVYGTCGPVKRGFVEALGVAPERVASSRDTGFAERFGRVDVVLNSLAGEFVDASRGLLGEGGRFVEMGKTDLRDPGEFPGVEYRSFDLLEAGPVRIREMFTELLPLFEDGSLTPLPVSTWDIRRCSEALRFMSQARHVGKIVVTVPRAFDPDAPVLVTGGTGGVGAHLVRHLVSAWGARHVVVASRRGLDAPGAADLVADHDGAVTVTACDVTDQDSLTALLGAHPDLQGVVHAAGTVDDGVLGSLTADRVRALLAPKADAAELLDQATRTHDLSFFVGFSSSAGVLGAPGQAGYASANATLDAVALRRRQRGLPGQSLAWGLWADTGMAGDLTDTDRRRLAEQGFPPLTADQALGLFDQATRRPEALLVPLRVDPRRLGAAAPPLLRDLAGPVRRTATTTAPAPDTSTLVRQLAGLSPAEAAERLTELAVDRASAVLGHDGTRRVQPDEAFADLGFDSLLAVEFRNGLNAATGLTLPATVTFDHPTPRAVGRALLAELDLDGVPSTSALLAQLDRIDAAVDALGADESGRAALAARLHALAERLTTPDTEAGAAGAVGVGDRIADASADELADLLSEEFGIS
>CP025990.1|AUS77120.1|166167_172509_-|modular-polyketide-synthase
MVEQDRMLHLLKQVTSELHETRNRLKRIEDRSTEPIAIVGMGCRYPGGVVDPDTLWDLVDTGRDATSDFPTDRGWDLANLFDDDPAAVGRCYTRRGGFLTGAADFDREFFGISPREALAMDPQQRILLETAWETFEHAGIDPTGLKGSDAGVFVGIPAAEYNHRSSPRDDVEGYLLTGNGCSVASGRLAYTFGFEGPVVSVDTACSSSLVALHHAVRSLRAGECSMALTGGVTVLSVPTIYVEFARQRGLSPDGRCKSFSDDADGTAWSEGAGMVLVERLSDALRNGHRVHGVIRGTSINSDGASNGLTAPNGPSQQRVIRSALASAGLSTGDVDVVEAHGTGTALGDPIEAQALIATYGQGRTPDRPLLLGSIKSNIGHSMAAAGVAGVIKMVQAMRHGRVPRTLHVSEPSSHVDWSGGTVALASDPTAWPDTGRPRRSAVSSFGISGTNAHVVLEQGPPVEPAPAAPETSPAPLVVTARSEEALRAQAGRLAAHLTAHPELPLGTVARSLATTRARLDFRAVVLAEDHAGALAGLDALTRDQPDPRVRTGTAVPPRLAVLFGGQGTQRAGMGRELHARFPAYRDAFDEVCAALDPEVGFSVRDAVLGADQDLLDDTGHAQPALFAVQTALYRLLASWGVRPDIVGGHSIGEVTAAHIAGVWDLPAACRVVAARAGLMRRLPPGGAMAALAATPSTVDALLVEGVEVAAVNGPTSVVVSGDADAVDRVVAAATGRGVKATRLRVSHAFHSARMDPVLAEFTRALETLEFREPQLVGLSNVTGGTADRWTEPAYWAEHVRSTVRFADNLAKLGDLGATAVVEVGADSTLAGMAGLVLDETVPVVSTLRRDGDEPAHVLTALGALFCAGTPVGWDTVLGHGEVVGLPTYPFQRERFWLSGSGQSADPRGLGVAAADHPVLGAVVDLPGDGGVVLTGRLASGTHGWLADHPVRGRVVVTVGALLEAAVRAGDEAGHDTVAEFQVAEPLAVPDAADVHLRVTLVPDGDAASALSVHGRVEGTTPWTELATGRLTSGGAATVPSPPETGDVEELSVSEGGALRRLRRSEDLVLADLDLPADHARDARHFDLHPALLDAALAAARTAGLLGADTVTATWAGLRLHAVGAAEVRAVLHRLGTGELDVLLADGAGQPVLTGRVTAFREATVATPEGTTAAEEDPLYRVEWTSASPTATEDTGSWHVLDEFAPAGALAAVDGEPDTLVWPAFPPADDEPRSVRAATHATLAVLQTFLAEERWSGARLVVVTRGGAATHPAHHAPVTATAAAVGGMVRSAQSEDPGRILLVDLPPGSGVPLDEVRSAVAVGEPQTAVRDAAVWVPRLQPSPAATVAPPPEGTWRLAADGRGSVDGVAPEATEPVEDLPEGAIRVSVRASGVNFRDVMTVLGMYPGEPLPLGLEAAGVVTEVGRGVDGFAVGDRVMGLCEGGFASEVVVDHRMWSRFPGSWSFAEAATVPVTFLTAWYGLRDLGRLVEGESVLVHSAAGGVGMAAVQLAREWGAVVYGTCGPVKRGFVEALGVAPERVASSRDTGFAERFGRVDVVLNSLAGEFVDASRGLLGEGGRFVEMGKTDLRDPGEFPGVEYRSFDLLEAGPVRIREMFTELLPLFDQGRIHPLPVSCWDVRQAGDALRFMSQARHVGKVVVTVPRPPDPEGTVLVTGGTGGVGRAVAERLVTHHGVRHLLLTGRRGPDAPGATDLVAHLADLGATATLVACDVADPDQTRALLDGIDAAHPLTGVVHVAGVVDDGLLGTLTPDRVDAVLAPKADAAHHLDRLTADLDLSFLTLFSSAAGLMGAPGQANYAAANAAVEAVALRRAATGRPARALAWGLWEGIGMGAGLSEQDVARISRGGITPLRPERALPLLDTAHRSTSPVVVPILVDTARLEATAGTAPPMLHGLVRRTVRRQASAATTGLDTAWTEELPGLSGMERQRVVLDVVTTQLAVVLGHADHRRIRPQQPFTELGLDSLTGVELRNRLAAATGLRLPATLVFDHPSPQAVAGALLTELVGDAGTDAPPADRAAPLRERIHRLEELLASADPTDEAYSGVEPALRRLLSTWSTRAAAPGGPDGDARGHDDVTDASAEDMFALLDSELGTS
>CP025990.1|AUS77119.1|159523_166135_-|hypothetical-protein
MASEEKYLDYLKRATVDLRHARRQLAELEDRAHEPIAVVGMACRFPGGADTPEALWRLLADGPDPVGPFPTDRGWRLDDLFDDDPTNPRTTYARNGSFLRDAGWFDPDPFDIGEREALAMDPQQRVLLELAWESAERAGIAPTSLRGGDTGVYLGVVAQEYGRGAPEAADVAGHVMTGRTTSIASGRIAYTLGLEGPTATVDTACSSALLALHLAVRALRAGECSLALAGGAAILGQPDMLVEFGTLRGSAPDGVCRPFAEDATGIGWGEGAGMVLVQRLSDALAQGRPVLAVLRGSAVNSDGASNGLTAPHGPAQRRVIQAALDDARLPGTAVDAVEAHGTGTPLGDTIEAHALQATYGRDRDDPLHVGSVKSVLGHTQAASGMAGLLSMVMALREGTLPRTRHTERPTTRVDWRTGALRLLTEPTPWPARDRPRRGAVSSFSFSGTNVHLILEQAPGAPTPPTATTAPTTTVWPVSARTPDGVRAQAARLRDALDTAADVDPHAVAWTLGTGRAALETRAVVLGHDLASLRAGLDVLAAEGTADPAGAALLVGTQEVEDPAVAVVFTGELPPGQAEDLAARFPVFAASYEELRPAGERIAHQIALFDLVVSAGITPEVVAGAGADEYAAAVAAGLWSRADALRVLTATPDQHRAVLDAVTFHEPDLPAVAERPVSTRDWLDPAYWSDRPGPSTGTAGAVDLAALAGEGTTVHLVLGTSPPATSPGPDIVVSVEDGPLAALARLHTLGRTVDWRRVLPARHPVDLPTYAFQRRHYWLGGGLEPAATAGTTDPTGRPAAPPDADATSGAGGDDSPERAARRAATRDRLAALPSATRERHLVRLVTRTVADALDQPAGGTVPARRSFTDLGVGSLAAVRIRDALAAETGVSLAVSAAFDHPTPRDLARHLLAALFHEDVAEPRPPRRPEAAPATGDTVALVGMACRFPGGSDSPDAYWRLLVEGTDPVTDVPAGRWDAAAYHDPDRAAPGRAYTQRAAYLPDIADWDATLFGYTAREAVRLDPQHRMVLELVWSALEDAGLSADRVRGSRTGVFLGMTDSQQYQARQAEAEGRSLADDPLFALGTSASAAAGRIAYHLDLRGPCLTVDTACSSSLVAVHLAVRSLRAGECDTAIVAASSATLSPEVFVQACKSHMLAEDAHCKVFDAAADGYVIGEGGAAVVLRRSRDVRPEDAPPHAVLRGTSINSDGHTNGLTAPSGAAQRAAITDALADAGLRPGDLDFVEAHGSGTALGDAIEFGVLREVFSRRDDDRPLLVGAAKSNVGHLLVAAGMAGLVKAVLALRARRLPPNQHLTTPSDQVDLDGPVRPATGTHPLPGAPGQPPRAGISSFGWSGTNAHLVLEAAPDPTHHHQDTGHPGPHLLTVSGATHQAARDNAVALADHLDAHPELRLSDVAHTLAAGRAALAHRLAVVASEPTEAVTALRAAATRTTTPTTGDTPHAVEATDDARPELAERLAAWGLGQDASDPASDPDPDPEAEAGTEVVLSTTGTGEFPLPDASDERGWLDLVGRLWERGIGVDLTPLSRPGARTLRLPTYRFHRVRHWPETTGHADTRPGAPAPGITFHGPTWHRDESPRALAPAEPGTVLVLAHDDALADGLRATGHTPVAVRPGQVLRLDGHPPHELDPGEADHLRQLLSEVDTGTGPLRVVHALGLRPAPDTPTALRDGPHSLVALVQAASAVAPTRPLHLLVASTGAADVLGGETLDPLRALPAGLNRSIRREYPSARVSCVDLDPDATDHARHVHIELSALAAPTPPDTAHAWRRGRRWRAVLDPLTLPAVPTRQVWREGGTYAITGGTGELALALAAQLAPLRPRLALLHRRTLPPADRWDTVLAEHPRGEDARVIGELRALRAAGVEAHPFTADVTDPDAVSAALEEAHERLGPLDGVLHLAGVAGGGLLQHRTRERADAVLAPKIAGTLALAEALRRRPVPLLALFSSAVTAVGGFGETDYAAANAFLDAFALAHDGTGAIADRVVSVAWGPWRRDRWQTEALADAPELRARMLRYRARSGISDAAGLDALTRVVAAGPPHVYALGDTLDGLTAQATGTGPEVEAAAGGVPAERRRPRPTLRTPYLAPRDDTERHIAEVWQDQLGVDRVGVHDPFFELGGTSLVGLSVVAHLSSHFGIEFAPANLFERPTVARFAELVRDPDDHTPEPGTTRAARRGERRRAVAARRRR
>CP025990.1|AUS77118.1|150087_159408_-|polyketide-synthase
MTESARESGDTGADIALVGMAGRFPGAPDVRRLWTNLRSGVESISRFTDEELRAAGVPADQLADPDYVRAGSVLDDIDLFDAGFFGYTPREAQLLDPQQRLFLESSWHALEDAGVDPARFDGTIGVVGGAALSTYLTHHLLGHPDLLELLGQVQVGLANDKDSLATRVAHALGLTGPAYAVQSYCSTSLVAVSLGCSTLLAGEADLVLAGGVTVSLPHRVGYLYQEAGMSSRDGSCRAFDATATGTPVGSGVGVVALRRLEDALADGDRVHAVIRGWAVNNDGSDKVGFTAPGVAGQAAVVAEALAAAGLEPADLDYLEAHGTGTPLGDAAEISAIQQVFDTEGVRLRIGSAKTNLGHLDRAAGVTGLIKTALALRHEEIPATLHLTTPNPQLARSGDRIRVVTDRQPWPRSSRPRRAGVSAFGMGGTNAHVVLEEPADTTPTAPLPARRHQVLVWSGRDAAAADESTARLATYLQGTPDLPSAAYTLQTGRAVLEHRRAAVVTSASDAADAVTTQAAQRLSTRVDATTGRTTGFLLAGVGEHYRGMVAGLHRTEPVFAEALDACRAVFARHLDGDPVEELLRDRETGGNDLARLLGRDTGPAADDDGDLARTEVVQPAMFAVDYALGQLVSSWGVRPRVLLGYSIGEFAAACLAGTLTLDEAASLVAVRATLISRLPRGAMAAVPLSSDELRHRYGTTGLGVDIAAENGPRFVVVSGAADAVDQLADRLARDGVPLRRLRTRHAFHSEALRPVADDLTDWARRNLSPRPPTIPYLSNVTGQLVTESQLADPGYWAQHMVSTVRFADMLGTVLAGGDDVLLELGPGQSLGAMARNHPDCEPRRWPLLVPTLPAEADPATDEAVLANAVAQLWLAGADVDWAAYHRGRGARKTTVPDYPFQRRRYWIEASPATPPGPTTRPGAAPDPAGHTPGRAAGTPPPATRTPTATGGPEILRPHWAPAPLPATPPPAPTGPVWILADDRGIGAALADRLPDHTCVLVHPGEEPDEDNGVLRPDDPADYRRLLDRTGLPAAVVHLWGVDTRTAGDATHALRLGFDSLCALATALGAAAGAPLPVTVVTDSARAVAPGDVPVAERATAFGACLVIPQEYPSLLVRAVDVRLPTEDLPALVAAEMWATGTDRFVAHRDGVRSTLDHRPAEPADTPTPWRPRADGVTLVTGGLGAVGLRLAARLGGHVVLTTRRALPAREDWPAVLDAAEDPALRARLRGLTDLAEQGASVEVATVDITDEDAMRALVTTLTHRHGRLDAVIHLAGLTDPAAFGVLAELDPAVRARHFAPKVRGTRVLERVLADVDVDRCVLFSSISTTLGGIGFAAYAAANSFLDAVAARNTGWSAINWDTWASTADALRDQDFGSSQVEHSLTEDQALTALDRVLAAPVTRTLVSAGDLAGRIRQWVDQGDDPTTPGDRFPRPDLAQQFVPPRGEVERRLTKVWEDVLAIDGVGSHDNFADLGGTSLMALQLVKRVQRVFGIALSAVSLFEAPSVRTMAALLERAGGTAEEEPADPPPAPAPDPTGAPDPIAVVGMAGRFPGAPDLGTFWANLAAGVESVTEFTEDELRASGVPEADIHSPDYVPRRPVLDDIRGFDAEFFGYSPRDASITDPQHRLFLECCWEALDDGGYGSARGRDRVGVFGGSNLSAYMARRQDAVRDGGEADLYASLIGNDKDSLASGVSYKLGLTGPSISVQTFCSTALVALHLACQSLRARECELALAGGVAIHVPDRVGHRYQPGGMESPDGHVRTFDAAAAGTLFGDGAGVVLLKRLADALADGDTVHAVIRGSAVNNDGSLKVGYTAPSVVGQARVVSDALRAARVRPEQVGYVEAHGTATELGDPIEVAALARAFGEGPPRQSCPIGSVKTNIGHLAAAAGASGLIKTVLALRNRQLPPSLHFTTPNPEIDFPASPFHVTTALTDWTPPPGGRRIAGVNSLGMGGTNVHVVVEEAPDPEPRPGTGHRRYQLVPLSGRTAESADAAVDRLRDHLAAHPGLDLRDVAHTLQVGRETFEHRRALVVSATDDLAAGGTAPATPLLRRDPARDRPVAFLFAGVGEQYPGMVRELYHREPRFRATVDECAAELADLVDVDVVALLTGPRTGPDSPEASELTRTEVAHLAVFVAEYALARLFLDWGVTPAVMLGYSLGEYVAACLSGVLSTRDTLRLLVHRAALIDTLPGGAMLTVALAPDTLDRRFGPLADRGVDVCAVNGEEMTVVGGTVEAVDALTRLLDEAGEPHRRFPSAHAYHSRLLRPAHEELTRWVAENLSPRPPRIPYLSNATGAPVTADQVTDPEYWARHMVSTVRFADGLGHLLADPDLVLLELGPGRSLGAMARAHPDCDRDRGPLIVPVLPAAVDTDADDHTLMGGLARLWLSGVDLDWSAHHHGEARRVPLPSYPFQRREYWLEETPRASHPGSPAPEGAPLDISALPLLEEPDWLHTEVWRQTPPRPTPPPAARWLLLVDDPDAPLTRSLAESLRAAGGTVRFALPDDDATEPRWDGDTATLRPGDADQLRAALRHTRELDELPDRVVHLWSLPDHAADGDQAHDPAGAVDTALTRGLHTLVGLAVAFRDLGSTSWALDVVTSGVCSATGTEALRPAWATLTGPVRVVPLEYPGVTCRLVDLDPAEPPASPRLARALTAELAADPADPVVALRGGRRWLPEHDRIPPAQPDTDARTTAGQGALRERGVYLVTGGLGGIGLAMAEHLATTCQARLVLFGRTGLPPRDTWDDILADPRTGEEVRRRVAGVRRLEGTGAEVLVVTGDVSLPEDTDRAVRAALDRFGALHGVLHAAGVPGIGLMQFKTRAEMARVLAPKVAGTLALTRALRAVPDLDFLVLFSSITATTGGGPGQVDYCAANAFLDAHARDPRRATEPWRTLSVGWGEWRWNAWEAGLAGYDSALQDYFRANRARLGIDFDAGWRSLLRALATDQPHAVVNTQDFTTLVRASSQFTVDAVNGPRPTDQPSPRHPRPDLVTPYVAPTGDVETAVAEVWAEALGLDRVGAQDGFFDLGGNSLVGIKVLADIRRRLDVDDLAPHVLYQAPTVGALAQLIAPDQAPPTPAVTETGGDRGQRRRAGLRAAQRRKNA
>CP025990.1|AUS81363.1|146506_150076_-|short-chain-dehydrogenase
MPEDDTRIAIVGMTGRFPGAGTVEQLWSNLTGGPTAIREITEEELAAARVPPAMLANPQYVRRGAPLDDPGLFDASFFGFSAREAEATDPQHRLFLECCWEALESAGYQPNRVPGRVGVFGGVGHSFYGLRHVLASPEVMDTITRGQYAMGTAPDSLCMVVSYRLGLDGPVFSVQSSCSTSLVAVHVAVQSLLTQECDTALAGASRIEEPVPEGYLFEEGSLTSPDGIVRSLDADANGTVLGNGVGVVVLKRLTDALADGDHVHAVILGSAVNNDGSARAGLVAPSVEGQSTVISDAMSVAGVDPGEIDYVECHAPGTRLGDSVELAALDRAFPTARDTPCVLSSTKPDLGHLDRASGMAGLIKAATAVERAQLPATRGFRQPNTALPRDRFRVLTTYQPWTTPGDTPRRAGVSSFGAGGTNAHVVLEQAPPRPAADPLPGPHVLVLSARTATALTAARLALRDRLADGTLTDTDLGDVAYTLQLSRAGFGHRLVCVADDLADAVAALDDPTRHRTAHPSSRGAPATRPGTLTTAADQWLDGADVDWAALHRRTVRRVPLPTYPFERREYFIPRPALGAAAAREDAGLPGHRLPDRADWINHPSWRRVPLPSVRDPGHARALGPWLVVADDEVGAAAAALLRADGAEVALVDPATVATPTDAAAFLREHGRPRALLHTASLAAPRPEDPAARFAAAQDRGFHSVRALAKALSEHPTPGDVDLLVCTGGAVNATTHDLTAPEQATLLGLLRVIAQEVGDLDCRLIDVDVTGCAAALGGTRELAAAVLTELGVDLVEPVALRGTDRWVRHFDRLPLPAPPARGRRIPEGGTVLITGGLGAVGQILAEHLVTTRHTRLVLTATTPLPPEDQWDEHLAHHDPASDRTAQHITTLRRLTGLGADVLALAADAGDPVAMAAALDVARQRFGPLDAVIHAAGTMRSDRYGPVVDLDRAACEEHFHSKVTGQRVLHDLLHEGEAPVRLAVSSMSTLLGGLGHGPYAAANSALDAQSVALTDTTPARWQTVDWDTWLTDGVDPRTLAPAIRDYTHDRAEGTDLFERALSLFDRAPHLVVSCGPLDERITNLTDSRGADKAPTLRHPRPELDIPYEEPTPGDETHLAAIWCEVLGLDRVGANDDFFDLGGHSLAGVRVMTRVRARFGGTKADVLIANPTVRRLATALAATATAGTGDQP
>CP025990.1|AUS77126.1|209082_210306_-|hypothetical-protein
MASVPGPRGHRRSGDRRWPSQRGTALRRRPAVTGRGSGTADPRHRAGRARQRGTTHHDGGAAAQHRRLIRKRGRRMRIRVLGAVRAEARGTALLLGGPKHRAVLRYLALRANSVVSIEDLLAALWRDEPPRTGRKMIQNTVSELRGVLAQDDDPSGGAVLLTHSPGYLLRIDPDRVDAGRFARHAEDGLRLLRDGDRRQGLDRLRSALAVWPPEAPQPAPGSLEAEWAEWRDLLRLRRAVEERIVEESEAGGALAARPEPDRPPREVIGPDGGGLGTSSVLLVTAESPATPGESPAETTHREAWAAARVHAHLRAAGGRVHVEFGSLVIAVLPAPPAEARAVAGRIRADLIGREGGRARTVSAVVLPAGPAEEPVPAALVDEGVRLLSERERGVEAAPAELLSEVRA
>CP025990.1|AUS77127.1|210512_211202_+|hypothetical-protein
MLGGVFLDAGLSVSAYLVFRWAGAGDYLALLAGTVVAGLRLGWVLLRTRRLDAFALFMTATFAVGLGLSFVTGDARFLLLKESVGTAVTGLLFLLTCLLRRPLLYAASKRFAGLDAAESTAWDERWRASPHFRRLFYRTTIVWGLGFVAEAVLRVPLVFLLPIPVMATVGSLGTPVLIVGLLGWTLWYGPRRELRVQEIERAESAGAAGTDRENALPAGTEARDRTTSG
>CP025990.1|AUS77128.1|211595_212591_-|O-succinylbenzoate-synthase
MTTGIDFEGARIYAIPMRARFRGITVREGMLLEGPAGWGEFCPFSDYDDTVSAGWLSTTIEQCAIGWPPAVRDRIPINCTVPAVGPERAYEITANSGCRTAKIKVADHPESLPEDLARVEAVRAALGRDGAIRVDANGVWDTDTAVSHIRQLDKAAGGLEYVEQPCRTIEELAIVRRAVEVRIAADESIRRADDPLRVAVAGAADVAVIKCTPLGGVRRSLRVAEAAGLPCVVSSALETSVGLAAQVALAAALPELDFACGLGTLSLFESDLVSGPGSLRAVDGFLPVPRTPPAPDPSLLATYELVEPEQAGWWRDRLARVRAVHGADRSG
>CP025990.1|AUS77129.1|212590_212893_-|hypothetical-protein
MIKQALDTYEPWRVRSRCFVQADLALAHLASRDLEQAASVGRDAVRMARQVSSNRVLDRLRMLQRRVRPLSSTSPDARELDDRITDLTRTRTHRDEDTAT
>CP025990.1|AUS81365.1|213185_213416_-|DUF397-domain-containing-protein
MDNDALAHAAWRKSSFSGSGGPGGGNCVEVAPLANGTIAMRNSKHPDAGVVFFTRAEMAAWIKGCKAGEFDDLDTQ
>CP025990.1|AUS77130.1|213442_214330_-|transcriptional-regulator
MSQDNGDVVNATVRRWQLTETLRQLRERAGLTIEQVAEQLRASGAGKWSRSKIGRIETREQGVRIREVEQLLDLYQVADANLRAWLLDLAATAHERGYWRAIRKDLPEDFHDFLNVEASLVALRQFETMLVPGLLQTPDYTRALISGMSPGLAAEVVERRVVARMARQQILTRPKPLDCHVILEETILERPVGTPVIMRNQLRRLVEEAEADHITLQVLPRTVGASPAMEGPFSVLTLPDPIPDFGYAEGSGGAAYIEDRDAVRACILKWAVLTERALPHTDSVDLVRKAAKEYQ
>CP025990.1|AUS77131.1|214564_214855_+|hypothetical-protein
MEPICDEAEFTALVRGMVADEAPRLFAVVQEYGDRVDAQIAAWGMVFGDRAEIVLLDGGTRVSATTPESALRGFHLGPHIRARLVWCAPHTAPRRG
>CP025990.1|AUS77132.1|215352_218211_-|LuxR-family-transcriptional-regulator
MRLCEREGEVAAIRAAVRAAHAGHGSLTAVVGPLGIGRTALLRSVADQLEETADTRVVLASGAPLEREFAHGVTRQLFEPAIWSADPERRSRWFAGAAAPAAPLLDADPGPPDPGPPEPVPPATLWPALRALAANLAAERPLLVVVDDLQWVDTESLRWLGYLARRLAGVPVTVVAAAWDVGCWSERPDVQDVLAAATRTLRPRPLGVDAARTLARDRFGAPVEEEFVTRAHAASGGNPMFLTGILDAVASSGAPATADQLTAEDSPWSGLLGDRLTTWLDAVVAPVRDVGRAVLVLGEEATPELVADLVGLDQLTCDRSLHVLGQLGLVDVDGTCSFRHPCASAAVDRAMGVAERERLRQGAALLLHQRGRPPERVAEHLLAVTTPQHAWATRVLREAADTALRRGAPRKAADYLRRLLLDVDDGVVRARLLVELALAEREFDRAAARRHLTQAVPLLPHPRERAVAATRLAPELLDEVTPAVRELLGRAEADLRSGEPLTGQDLEIALRVECRVRRAGLAPDTEDSVLDRLRDLDVVPGGRTPAERELVSVLLHQATGGLLLSSDAVGRIGRAVLAGEPAAARHVHTGLVLLPPTLVAADAAEDVGTWLDIALDQARRQNSVVARVLVSVGLVSVRLGAGDVTGARTCGLDAVALAESEWPDGLPLCLAALVPTALLPRDARMARWLLDRLERHATGSEGAAYHHDALLPLRGFLRSHAGDLPGALHHVQECGQLLARAGRRNPALSPWRHWATSLHLRMGDPAAARAVAAEEYDLAVRWGAPATLGAALRLLGTVTDGRRGIELLRESRRVLAGSGNRLELGRTLAELGRALLRAGDPAAEPVLREGHDLTADRGIDWLTDRFRFDLAACSRASGVDLVLTRAELRVAVLAAEGRTNKEIADTLTVSVRAVEKHLTRVYRKLAVDGRSGLAAALVPVSTGPGDPSTRAC
>CP025990.1|AUS77133.1|218255_220778_-|hypothetical-protein
MNPDQPAAPPATSAASVLTGRRHWQDQAARAHLLDRAPQLAILRRIVSQLLASTPSVGVVEGTPGSGRSALLLHAAAAAERRGARVVLARGTPAETRLRHGITSQLLGALTPPGSSLWTSPVWTDPDRDAELVPLLCRDFLSVARQQPLLVVVDDAHWADRWSVGWLGALRRRLRDVPLALLLAGDTGAVPLSPRAEGAPHGPDRVTAPHLLAVGPLTPESVRTALGRAGAPAPETLARAATDATGGNPWLLDVLRRHLGSASVPPEDLAATDVWRVVAAAHGDRVTRLAATLEAEPAGLLRALAATGGRLPFRLVAALAGLRDASERVVLDRLAGMGLVRGRGGPDDRPDVVGPIVRDRVLAEMPTHDREDLYARAADLGHRSAVDDVDVAELLMRAPSGGGGWAVGVLRRAAHQARATGHPDDAARYLDRALREPLAPTTRVNTLIERAAVSATADTGERYLADVLADAGGGRAPGEATLRAADLLLAGGRGRTAYWQLSALADAHHADTTPEEIHAPFTALCQLAHATQRGEPGGLVELAPPPLPPDPGDPARSAALAHALAVAGVDLTRTVDLARRALSPNGQPATSAPLTAALTAPRLAAARALSLAGRDEEALDAIDTVLAEARRQAPSWVVARVLTVRAGTALRAALPAEVDRTLALISDALPAVRRSRSLAAQVASVRALHHLDVGDVADAERALRTCPPDVTIGGEIGARVLYTRGRLSLALGEPGKALADLRQCGWRLLARQEPNPALLPWRGHTATACLATGDVAQATRLFDEERELAGRWGAPAPLRRTEELAARAWSTLHRTRRRDLVEPGYPLGRRSGEPGREDVR
>CP025990.1|AUS77134.1|220774_223555_-|helix-turn-helix-transcriptional-regulator
MGPVIVGREREFDQLAAHTDHVRAGLARLVVVTGAAGTGRTVVLDTLRRRLAADFTVLRAACRPSSATRHRGTVHALLAPLGHHPGPADAGDDTHEALHAPYRRVSQLMRHRPLALVIDDAQWCDAASLRWLDFLLRRTTRGPLLVVLGWHDAVRAPADPVLTRLLRGPGAAGLPLPPLTEPAVAELVREAFDGPGTPSFVRRCHDLTGGNPALLRRLLDELHTAGITPDDRDAHRVTELGAEVRRRSALIRLDTLPDHVRVVARALAVLEDPGPGATPGIGLVAALAGVPEHVASHAMTALARAGLVTGGRFTHTTGRLAVLTAHPADELPRLRDRAARLLNDAGRPAEEVALRLLERNGPLEPWMTGVFREAADAARRRGAPEDAASYLARVLAAGGPLTPPVQLRIELARPLAQVDPAAALAHLAPALAGTTGARDRASLAVQVGLTAVSAQRAPEGTRVLADARAELIAAVGDNPGPTDRELRAQVESTLLLTGIQEASTLAETRALARSIPAPPGRTPGERQLLGVLAALDAGGGTDLPRSLDLAERAVRVPEGTGDWALVSATFALHLADELPTALTVLDRLTDPARRRTHSGTLSVALANRAHVLFAAGRVRDAVADARDAAEAAARNPRRTRAAWPNTMLAVTLVAHGDLPGAERALLLARRPGADRVVWNHPYHLLARGRARWQSGDTEGALHHLRRCGDHLDRTGITNPLFATWWVDATAILVELGRRTEAGELAHRQHERALRWGAPRAIGLGLTARGLAESGRRAVALLSDAVDLLATSPARLCLANARFRLGEALLRVGRNRQAREHLRAALDLSTQCGSQALFLAASRRHAAAGGRRRSTGPAAVDLLTGAERRVAALASAGHTNREIADALFVTVRTVEVHLTNTYRKLDVPGRAALRAVLPEPDPTGQHR

Crispr_ID: CP025990_6

• CRISPR_ID: CP025990_6
• CRISPR_location: 408215-409095
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 13 spacers
• Cas_protein_info: cas7,cas5,cas3,cas4,cas1,cas2

Consensus repeat of CP025990_6

Consensus_repeat	Method
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CRISPRCasFinder
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CRT

spacers of CP025990_6

>6.1|408245|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGCTCCCATCGGAGGACCGGCGGAGCGTCGTCGTG
>6.2|408310|34|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTGGCGGACGTTGCGTTGACGACACCCGCCGCGA
>6.3|408374|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCTGCGGATTGCCCGCGAGCGGGCTACTGCCGAGA
>6.4|408439|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCGTGGCTGGCCGACTGCGGCGGCCGCATGGACCCC
>6.5|408505|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGAGGTGGATGCGGAAATCGCAGTCCTGATTCGCGA
>6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGCTCGGCGCGCACCGCGGCGAGCTCGGCGCGCAG
>6.7|408636|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACGAGGCCGAGATCCGCGTGCACCGGTTCGCCGCCTC
>6.8|408703|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
ATGATGCTGCCCACCGGGTCCACGGTGGGCTCGACCT
>6.9|408770|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGCGAACACGACGACGCCGCCCCGACGACCGGGC
>6.10|408835|36|CP025990|CRISPRCasFinder,CRT
GCCGCGTGGGCGGCCACCCGCCACCGGGAGACCGGC
>6.11|408901|34|CP025990|CRISPRCasFinder,CRT
CGGGGAGGTAGGCCCATCTGGTCCTCGATCGCGG
>6.12|408965|35|CP025990|CRISPRCasFinder,CRT
TCCTGCGCGTCCCGCGCGTCCGGCGTCAGCGCCAC
>6.13|409030|36|CP025990|CRISPRCasFinder,CRT
CGGCTGGACACGAGGTCAGACACGGCGCCGGATCTC

CRISPR arrays and Neighbor proteins around CP025990_6

CRISPR arrays

The CRISPR arrays of CP025990_6

>merge|CP025990|6|408215-409095|PILER-CR,CRISPRCasFinder,CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAACTGCTCCCATCGGAGGACCGGCGGAGCGTCGTCGTGGTCCTCATCGCTCCTACGAGGAGTTCCAACGTGGCGGACGTTGCGTTGACGACACCCGCCGCGAGTCCTCATCGCTCCTACGAGGAGTTCCAACGCTGCGGATTGCCCGCGAGCGGGCTACTGCCGAGAGTCCTCATCGCTCCTACGAGGAGTTCCAACGCGTGGCTGGCCGACTGCGGCGGCCGCATGGACCCCGTCCTCATCGCTCCTACGAGGAGTTCCAACCGAGGTGGATGCGGAAATCGCAGTCCTGATTCGCGAGTCCTCATCGCTCCTACGAGGAGTTCCAACCGCTCGGCGCGCACCGCGGCGAGCTCGGCGCGCAGGTCCTCATCGCTCCTACGAGGAGTTCCAACACGAGGCCGAGATCCGCGTGCACCGGTTCGCCGCCTCGTCCTCATCGCTCCTACGAGGAGTTCCAACATGATGCTGCCCACCGGGTCCACGGTGGGCTCGACCTGTCCTCATCGCTCCTACGAGGAGTTCCAACCGGCGAACACGACGACGCCGCCCCGACGACCGGGCGTCCTCATCGCTCCTACGAGGAGTTCCAACGCCGCGTGGGCGGCCACCCGCCACCGGGAGACCGGCGTCCTCATCACTCCTACGAGGAGTTCCAACCGGGGAGGTAGGCCCATCTGGTCCTCGATCGCGGGTCCTCATCGCTCCTACAAAGAGTTCCAACTCCTGCGCGTCCCGCGCGTCCGGCGTCAGCGCCACGTCCTCATCGCTCCTACGAGGAGTTCCATCCGGCTGGACACGAGGTCAGACACGGCGCCGGATCTCGTCCTCATCGGTCCTAGGGCGAGTTTCAGC

>CP025990|6|5|408215-408834|PILER-CR
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	TGCTCCCATCGGAGGACCGGCGGAGCGTCGTCGTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GTGGCGGACGTTGCGTTGACGACACCCGCCGCGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCTGCGGATTGCCCGCGAGCGGGCTACTGCCGAGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCGTGGCTGGCCGACTGCGGCGGCCGCATGGACCCC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGAGGTGGATGCGGAAATCGCAGTCCTGATTCGCGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGCTCGGCGCGCACCGCGGCGAGCTCGGCGCGCAG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ACGAGGCCGAGATCCGCGTGCACCGGTTCGCCGCCTC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ATGATGCTGCCCACCGGGTCCACGGTGGGCTCGACCT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGGCGAACACGACGACGCCGCCCCGACGACCGGGC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC

>CP025990|6|5|408215-409095|CRISPRCasFinder
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	TGCTCCCATCGGAGGACCGGCGGAGCGTCGTCGTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GTGGCGGACGTTGCGTTGACGACACCCGCCGCGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCTGCGGATTGCCCGCGAGCGGGCTACTGCCGAGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCGTGGCTGGCCGACTGCGGCGGCCGCATGGACCCC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGAGGTGGATGCGGAAATCGCAGTCCTGATTCGCGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGCTCGGCGCGCACCGCGGCGAGCTCGGCGCGCAG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ACGAGGCCGAGATCCGCGTGCACCGGTTCGCCGCCTC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ATGATGCTGCCCACCGGGTCCACGGTGGGCTCGACCT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGGCGAACACGACGACGCCGCCCCGACGACCGGGC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCGCGTGGGCGGCCACCCGCCACCGGGAGACCGGC
GTCCTCATCACTCCTACGAGGAGTTCCAAC	CGGGGAGGTAGGCCCATCTGGTCCTCGATCGCGG
GTCCTCATCGCTCCTACAAAGAGTTCCAAC	TCCTGCGCGTCCCGCGCGTCCGGCGTCAGCGCCAC
GTCCTCATCGCTCCTACGAGGAGTTCCATC	CGGCTGGACACGAGGTCAGACACGGCGCCGGATCTC
GTCCTCATCGGTCCTAGGGCGAGTTTCAGC

>CP025990|6|5|408215-409095|CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	TGCTCCCATCGGAGGACCGGCGGAGCGTCGTCGTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GTGGCGGACGTTGCGTTGACGACACCCGCCGCGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCTGCGGATTGCCCGCGAGCGGGCTACTGCCGAGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCGTGGCTGGCCGACTGCGGCGGCCGCATGGACCCC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGAGGTGGATGCGGAAATCGCAGTCCTGATTCGCGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGCTCGGCGCGCACCGCGGCGAGCTCGGCGCGCAG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ACGAGGCCGAGATCCGCGTGCACCGGTTCGCCGCCTC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ATGATGCTGCCCACCGGGTCCACGGTGGGCTCGACCT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGGCGAACACGACGACGCCGCCCCGACGACCGGGC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCGCGTGGGCGGCCACCCGCCACCGGGAGACCGGC
GTCCTCATCACTCCTACGAGGAGTTCCAAC	CGGGGAGGTAGGCCCATCTGGTCCTCGATCGCGG
GTCCTCATCGCTCCTACAAAGAGTTCCAAC	TCCTGCGCGTCCCGCGCGTCCGGCGTCAGCGCCAC
GTCCTCATCGCTCCTACGAGGAGTTCCATC	CGGCTGGACACGAGGTCAGACACGGCGCCGGATCTC
GTCCTCATCGGTCCTAGGGCGAGTTTCAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77238.1|418868_419294_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77231.1|410712_412152_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|187853
CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|274215
CP025990.1|AUS77230.1|409990_410716_+|CRISPR-associated-protein-Cas6	unknown	unknown	gnl|CDD|224499
CP025990.1|AUS77228.1|401573_404336_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS77223.1|392495_393320_+|dehydrogenase	unknown	unknown	gnl|CDD|212491
CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl|CDD|273860
CP025990.1|AUS77227.1|399432_400656_-|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|181146
CP025990.1|AUS81376.1|393440_394208_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235975
CP025990.1|AUS77226.1|396678_397785_-|alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176240
CP025990.1|AUS77239.1|419692_421294_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341259
CP025990.1|AUS81378.1|404739_405930_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
CP025990.1|AUS77225.1|395850_396534_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
CP025990.1|AUS81377.1|397852_399280_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143456
CP025990.1|AUS77224.1|394413_395634_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173844
CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl|CDD|366863
CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|187770
CP025990.1|AUS77229.1|406505_407789_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|238045

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	3.9e-56	185.3	0.0
CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1e-20	68.5	0.0
CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	3.5e-52	172.1	0.0
CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	9.3e-36	118.1	0.0
CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	6.6e-94	309.4	0.0
CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	3.2e-19	64.1	1.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	6.89138e-54
CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.35232e-119
CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl|CDD|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	4.72222e-55
CP025990.1|AUS77230.1|409990_410716_+|CRISPR-associated-protein-Cas6	gnl|CDD|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.83323e-13
CP025990.1|AUS77228.1|401573_404336_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	4.36908e-14
CP025990.1|AUS77223.1|392495_393320_+|dehydrogenase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.22413e-46
CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5	gnl|CDD|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	6.0735e-15
CP025990.1|AUS77227.1|399432_400656_-|acetyl-CoA-C-acyltransferase	gnl|CDD|181146	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase.	0
CP025990.1|AUS81376.1|393440_394208_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|235975	PRK07231, FabG-like, SDR family oxidoreductase.	5.75784e-111
CP025990.1|AUS77226.1|396678_397785_-|alcohol-dehydrogenase	gnl|CDD|176240	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase. Glutathione-dependent formaldehyde dehydrogenases (FDHs, Class III ADH) are members of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. Class III ADH are also known as glutathione-dependent formaldehyde dehydrogenase (FDH), which convert aldehydes to corresponding carboxylic acid and alcohol. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	1.43206e-145
CP025990.1|AUS77239.1|419692_421294_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|341259	cd05936, FC-FACS_FadD_like, Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD. This subfamily of the AMP-forming adenylation family contains Escherichia coli FadD and similar prokaryotic fatty acid CoA synthetases. FadD was characterized as a long-chain fatty acid CoA synthetase. The gene fadD is regulated by the fatty acid regulatory protein FadR. Fatty acid CoA synthetase catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions.	0
CP025990.1|AUS81378.1|404739_405930_+|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	3.63729e-15
CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.03711e-22
CP025990.1|AUS77225.1|395850_396534_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.54359e-14
CP025990.1|AUS81377.1|397852_399280_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143456	cd07138, ALDH_CddD_SSP0762, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like. The 6-oxolauric acid dehydrogenase (CddD) from Rhodococcus ruber SC1 which converts 6-oxolauric acid to dodecanedioic acid, and the aldehyde dehydrogenase (locus SSP0762) from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 and other similar sequences, are included in this CD.	0
CP025990.1|AUS77224.1|394413_395634_+|acyl-CoA-dehydrogenase	gnl|CDD|173844	cd01155, ACAD_FadE2, Acyl-CoA dehydrogenases similar to fadE2. FadE2-like Acyl-CoA dehydrogenase (ACAD). Acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACAD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. ACAD's are generally homotetramers and have an active site glutamate at a conserved position.	0
CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein	gnl|CDD|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	8.60246e-46
CP025990.1|AUS77229.1|406505_407789_-|XRE-family-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.42932e-08

Protein sequences

>CP025990.1|AUS77229.1|406505_407789_-|XRE-family-transcriptional-regulator
MVLTSMGEAYAGVRQRRVRAAKGTSVKLEDDLIGTRIRQIRHWRGMTASSVAGPAGISRSYLSRIELGGRAVSSRSLLEALASALRVAPSALTSEPHKTLRRGDQSAHDVIQSLDSALTSAMPGERPEDTTPRPLPALAAAIDGVNAARHACDYPALADLAPRLVRELLVLYASGPHRRQAGEWLASTYQAIMDAAKALHGVGLPALAYTHVRTIAEDLDDPQLRGLGYWMRGQAFGPGRRREQVAFSAAAAGSLEPHIGEPGVLEAYGQVHLNAALGAVASGQHDVADAHVREARDAARRVSGPGSPWAGLWFGPTNVAVWSLVIASEKKDIGAVDRIAGQIDIDVIPYAGRRAAFYSEWGRAVLSETRSRERGLALLLKAEKLAPHRVRNHPLVRDAVSSLLVRSRREAGAGALRGLALRMGIAT
>CP025990.1|AUS81378.1|404739_405930_+|PucR-family-transcriptional-regulator
MRSRASAEAVAVVHHAARSLLSELPQLTDHLVALLREQEPAYRSAATDFDGLWREVHESLEHNIRSILAPRETRESARRCSWRIGAERAEQGLPLDALLHAFRLGGGVVWQGLVDATTRSDPDRVHLLVHVAADVWNFVDEHCGLLADAYRKVEGQLTRRREERLRALVGALLDGSTRLADVPAVAAALDLPQQARYAVVVVAGQGRAVLRDPGLRVGVPGTRIIWHTGVEEELGIVQLGDVAVADLAAALTVPRGCRVGVSPAVEELAAVGAARRFADTALRTCEDDAQVALLEDHLPSAMVVSCPELSAALTRRALGPVLDLDPPDRKVLLSTLEVWLDCDGSALRAGTRLFCHRNTVLNRLRRYEQLSGRSLNRQRDLLELALALEAQRLLGE
>CP025990.1|AUS77228.1|401573_404336_+|helix-turn-helix-transcriptional-regulator
MDPPPTPPGAPGGVAPLPARGTFAPAARAGPPPTALDRLPADTRRLVLVAAAATVFDGPPALDLLHRAARRAGLSPSCLDPAEDTGLLVVDGDLVRFRDPHLRDAVYREAPRPHLRAAHAVVADVLDPGPGGLRRLCHRAAATVGPDDRLAAALARAVDRHSPTGRGPLLDHAQCSTALASAARLTTDARRRARRVLAAVDHAWLAGDPRRAWALLTAPELPAADDDVVGRRELVRGALELRGGVVSDAHASLELAAALLRPHGGPLARAALMDRLAASWASGDLPRHLAALDHAAADDPPGPSTAGNRPAAETPPAPTSGHRLPRAPRFPDVRLAARLAGVRAAAHTQPWAHPAAARPHPPGGGLVSWCEAPRSAVRPTPSWTVHRHPGLPGTRTPPEATERPLPAPRQPPDPPRPGRHPSGWEADYAGGLAAVLRGRPHEGTPLLRRMLDGELDGAVPLFAATVAALAAGRPRDAATAAARALASARAGGPAALIPIALEHLAHTELVLGDHARAHSHASAGLRAAHRAGQPNQATHHRALLAFTSALLGEEESCHDHAARAAREAAARGLVFAETLATWALAMLDLAGRRPETAADRLRPLLVGSGPRGHFAAREFAVPSLVEAAVLAGDTHGVHAPLRRFERWAAATGDPDRRAQALRCRALLHADDSGADALFREAIDLHERAGQGFEQGRTRLLHGEALRRRRSPGAARDQLRAALVLFELCGARQWATRARDELRAVGDSPPRAVNLAGRRRRTVDTDRLTPQQLRIARAVASGNTNREVAVSLRLSPRTVDHHLRNVFATLGVRSRVELTLLLSNGGSDRDDTPAASGVGVGVAVGRHPTGREAAGQASVTALATAPRRRLPPGQQPVFGRPRNPATTTSGEAPPRPTSETSAPRRRSLPSRPGGQAEEAGA
>CP025990.1|AUS77227.1|399432_400656_-|acetyl-CoA-C-acyltransferase
MPEAVIVAAARSPIGRARKGSLRDVRPDDLAAAMVRAALDQVPELPVEDVEDLYLGCGNPSGEQGFNIARVVAVSLGLDALPGATISRHCASSLQTTRMAFHAIRAGEGLAYVSGGVECVSRIARPADAQAGGRGENPRYAAAMARSATRAGGGAPPWEDPRLSGELPDVYLAMGQTAENVAQHRGISRREQDEFAVRSQRAAARALDDGFWAEDITPVTLPDGTVVAADDGPRPGTTLDRLAGLAPVFRPDGTVTAGNCCPLNDGAAALVVMDEDRAGDLGITPLARIRSTGVSALSPEIMGLGPVAACRLALRRAGLGVGDLDLAEINEAFAAQVIPVHRDLGLDEDRLNVHGGAIAVGHPFGMTGARLTATLLHGLRVRDGQFGLVSMCVAGGQGMAMVVERLS
>CP025990.1|AUS81377.1|397852_399280_-|aldehyde-dehydrogenase-family-protein
MPPDRLYLDGRWTAPRTSTPIDVEDPATGELLGRVAAAGPEDVHEAVLAAERAFPAWAALEPGERADHLDALRSAMADRAADLAELVTAELGTPIRFSRAVQVGLPLRVLESTSALLRDPGFAAPERLGHSLVLRDPVGVVGGITPWNYPLHQAVAKIAGAFAAGCPVVLKPSGLTPLSALALADLADRAGLPPGVLNVVPGGGRVVGEALVRHPGVAVVSFTGSTTAGARVAALAGERLARVALELGGKSASVVLPGADLARAVRRTVDSCLLNAGQTCTAQTRLLVRHDRYAEAVDLAVAASQRYRPGDPTDPETRLGPLVSADHRRTVTGHIARAVHDGARLAVDGRDAAGPDGRGHYCGPTVVVDADPAAAIAQQEVFGPVLTVLPYRDEEEAVRIANGTPYGLAGAVWAEDDDTATAVARRLRTGQVDINGAPFNPVAPFGGYGHSGYGRELGPHGIAEFQQLKAVQLPL
>CP025990.1|AUS77226.1|396678_397785_-|alcohol-dehydrogenase
MPSTAVGAVLRATDQPLRVEEIELRDPGPSEVRVRMTAAGVCHSDLSLARGVLPHHLPAVLGHEGVGDVVEVGEGVTGLRVGDQVVLNWSPPCRDCWFCRGGQPYLCQASLRYATRPHAVGADGQPLFPGLGAAAFATETLVAEDACVPLPPGTPAVEAALLGCAALTGVGAVRNAARVRPGESVVVLGLGGVGLCAVQAARIAGAAPVIAVDPAPDKAALAESLGATEVLEPGPELARRVRRLTGGRGADHAVECVGRATSIRAAWDVLRRGGRATVVGLGERSDTLTLSAAEVAMLGRTLAGCMYGDCDPAEDLPVLLGLLGAGALDLGSLVDRRIDLAEVEDVFADLDRGRGARAVVVFDQGDQG
>CP025990.1|AUS77225.1|395850_396534_+|GNAT-family-N-acetyltransferase
MAPCQHEWLPSRVAARASRLVSPPPSRTTATTSPRSTAWRTPTPRAVGPSTSAVGLVADRRPATPDFTIRPARLDDWPRIWPIVEDVVTEARTLPYDPGMGADDARRMWLLPAPARTVVAADGDRVLGTANMYANRPGPGSHVASGSLMVARAARGAGVGRALTTDLIGWARENGFAAVQFNAVVDTNTSAVRLYESLGFVTLGVAPGAFRHPEHGDVGLRIMWLDL
>CP025990.1|AUS77224.1|394413_395634_+|acyl-CoA-dehydrogenase
MDFAHDERTRELADRLRGFMAEHVHPAEEALARGEADPGPEWGPPPLLAELRAEARRRGLWNLFLPGEHGAGLTTLQYAPLAEITGRSPRLAPAALNCAAPDTGNMEILALAGTEDQRRRWLAPLLDARIRSAFAMTEPDVGSSDATNIATTVERVGAEYVVNGRKWFVSGALSPECELLIVLGRTSEDGPARERHSMVLVPTGTPGVTVRRGMSQFGYSDDDHGGHAEILFEDVRVPAANLLGEPGSGFAIAQARLGPGRVHHCMRLLGMAERAVELACARAATRTTFGRRLSDQGVVREWVAESRVRIDQCRLLVLRAAWLMDREGNRAARDEIQGIKIAVPRAVEWVVDRAVQIHGAAGVSQDLPLARFWAIARSLRIADGPDEVHLRSLGRREIERQLAALA
>CP025990.1|AUS81376.1|393440_394208_+|SDR-family-NAD(P)-dependent-oxidoreductase
MPTADGTPRLAGRVALVTGAGRGIGLAIARRLLAEGARVCVTARHAEPLAEAAADLGGPDRVLAVPGRSHDAEHRAEAVRRTVERFGRLDVLVNNAGTNPVRGPLLTAGLDAVRKTFEVNVFAALGWVSEAHQAWLGEHGGAVLNVASIAGLDTSPGLGVYGASKAALIRLTGQLAVELAPRVRVNAVAPAVVRTRFAAALYEGREDRVTSAYPLGRLGDPADVASAAAFLVSDDASWITGQTLVLDGGHTLRPA
>CP025990.1|AUS77223.1|392495_393320_+|dehydrogenase
MTSSFSFHGRLAVVTGGGSGIGRALASGLAEEGARVVVADLDAAAAARVAAALPGGRGVPLALDVTDPVALDRAISGVEAELGPVSVFCSNAGIAGSRLLGSPEEWERMWLVHVAAHVHVARRVLPGMVARGEGRLLVTASAAGLLTTLDSAAYAVTKHGAVAVAEWLAIEHHDAGVRVSCLCPQGVATPMLTGSDGGAPATTAAGGVRSAEDVAAEALDALRHGRFLVLPHPEVGEFERRRATDRERWLDGMRRLRRRLRPADPHLAGGTSPG
>CP025990.1|AUS77230.1|409990_410716_+|CRISPR-associated-protein-Cas6
MTTTAPGIPWAEVLRPGRGIVYQMLGDNAPALGAELHSAGFGPHRLVPVGCGAPRFPRARRQRGRYAAGGEGTLEFGSPLPEVIEALAAGLAGARVLDWGGVALRVQNVVSVPAPEFSDGSARLATTTPVVVKGPPARDAAGARLRSQRWLLPGEPEWDVFFVRNLRRKAETLGLDPEISLTEVWRVGPKRSFAVGQGDTVGAKVGAAVGVTLVGSPDTLAAVWSWGLGAANIAGFGAVET
>CP025990.1|AUS77231.1|410712_412152_+|hypothetical-protein
MTAADMRATSTGEPFLVELTAHPLQRVGAFALAVLAKESHPRRVSEDRFLRVWNRMTEDAVAATRETDAKQPGAFLLSASYALWPNSKMNIPSLRKLSADQRGQAVVEWRTPRPPESWPEAPCALCGRRACGFYGKVDVPLAMSTEYRNTTVVGHDGMPLCRTCLGSFYALPYACHFQGGRATITHAWDEDFLSFATRHQVEDTRKRIGRVSVTPSKWPAYVRESLLVNRIRAYGHPVRSDVSLIIFTNNNQEQELTEQRMDQPLVEWIHAVRQDKTSDPWNSLERACHSEKVPGAAALAGELVRSPRRLPAKVLRYLGPLLTSAPDTRDEIRQLVGALRSFVGKVLHVNDRELQEIEGLGKRTAALMMATRKKVKPFVVAYRKSTTFRKWFNDGAVEWLLWRDREELTSLIDTTEPFVTPTHLRWLFEPDEQAWLRRNLLFVAVIHELHSQGYRPDSDDTRSIEDTLHTDGEDKENDE
>CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MTYLVGTLVLEIKAGAPNNGRGEDNVGKVKATRVGNRVFPYVSAQAVRRWWRDSLPPGEARSPVIRSGKGAKQQAHTQGRGDLYLDDDLFGYMVAIEKKSFNRDTVLAVGTAVSVAPRQVTHDFGTMSRGFEVGADPVIHEHEHYTGDLACPVLLDLARLGTFQLEGQGNRPDLNPDAAKEARVNGAEEIDFRFGQALRLPLAERRRRAAVLWRTLAELRGGAKQALHYGERSPALVILAPVKGGNNPFTRLLRHDLGETVVALDVLRAEMRAWEDELDGPVRIGWAPGYLERQRDAAERELKDLVDSGQVVFDHPRVVLRQLAAELEGGDLDSWFEDRS
>CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5
MSVPALEVTFDASVASFRNPLYPGLQVGLPCPPPSTVGGLLAAAAGGWGQVPRDTRFALCCHAEGHGTDLETFHPLAEGVRQPSPVPKDRDYLWGVRLTVWLFEDLDRWYRRFRRPVWPLRLGRSQDLCSARAAWVDLREQPGRQGTALLVDRPDAVGTRLRLTTAISVDRARMRWDDYRHSSDAAAARGVLSDGWSTHDGQAVIPLPPTHPEVVEARS
>CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3
MTEDLPHLWAKSPAKEATTGESLTEHSARTSAVVPLIRARIGVVDGIWDESWWPAVQLAALLHDGGKIDPGFQRQVRTNTRWGLRHEVLSLGFVDLLVTDQEVRRRVAAAVVTHHRPLHGDATRSILPDNLSQDQQALGQAFTVAEDDGTVRALAAWFADAAARVGLPVDRSRLGGLTRDDIRAGTLTLLRDLAEDWWYPGTEQGGLPWVLLQGVVTMADHVASAHGELLTGEPLRGYGDRVRVRLAAAGHRLTRAQEEATAAHHLLLVSPTGSGKTEGGLLWAEAAWRQVAEQRNALPRVFYVLPFLASINAMALRLQEEDGVEDVGVLHSRAGMFHLNELIEARAAGSDDRPEPTVDDAATALDHVNASRTHRELFRVTTPYQLLRAAFGGPGDSSTLADTVNSVFLFDELHAYEPRRLGMLLAMIRLWTQELGGRVGVLSATLPERFRRILRDTIAGRLDVVDGFAGVRHTPRHRLRIGGGHLTSPESVDRIAADLHAGQAVLVVANNVADALDLYDLLGPVAKEQGGEAVLLHSRFRNCDRAQKEKRILELFGTDRRSSRGLLVATQVVEVSLNVDFDVLHTSGAALEALLQRFGRVNRRGKRAPASVWVCEPEYRRRRGGGEETWADGVYDEVPTRLCWAALQNHDGETIDEADAQQWLNAIYDSPWGDTWEKEVLVSQERFDEDYLDFRSPFADREGLRKEFFATFDGVEAILSDDLADYQADRRQGEKGQGALLASRFLLPLPVHLSSSGHFDRRHGITVINGDYHPELGLKGIVRETRYQPGEIL
>CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein
MISADDVGGVHIKYLYHCRRQLWLYSRGFRPEQLSETVALGTAIHDISYSRFSPVDLGAATLDHLDNQLWVHEVKHSDKRREADRAQARHYCHQLTRVGVDVQGAVLHYRSPRKTERFPYTEEEHMHASEDIEQVVATIALPESPPRLPKSRCRGCSYSDYCWSV
>CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1
MPAASRTYWLLNPCRLRRQDDSIRVEREGKPPAFVPIKDVRDIIALAEVDLNTSMISLLNKHRVAIHILSHYGDYAGSFLPAETSVSGTVALNQARIASDDGESLTIARSLVDTAAFNIRRVIDRKLLTRPYGVLTEALEAATTREQLMAAEGNFRRSAWEALDTKLPDWLQLDGRSRRPPRNAGNAVISFINGTVYARILTGLRLTPLHTGVAFLHASTQRHRHSLALDLAEVFKPLFAERILLRLANRKQLKKHHFDVGSNQAMLSEAGRKFIVQTVRDDLAESVNHRTLGRKVTYDELIYLDALALTRTCLEGTPYKPFRIWW
>CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2
MYTILVYDTAAERNAGVLRTCRRYLRHQQRSVFEGELSAAQFVRLREELRQRIDADYDHILVYTFPPGTDPQRQAWGRPDDEPPDIL
>CP025990.1|AUS77238.1|418868_419294_+|hypothetical-protein
MFGTRWRSGTGSGGCVFGAAGVVIGGGMTAQVDAALGALVRHGFVFRHAPGDRYVPWTLFGQRPRGAYGDYLHVSGPDDCLAARMRTSSQPAPSDVVWCEEGAFLDTVSALLSLPAPDVANAPRLATRRTAALWTPGMPLG
>CP025990.1|AUS77239.1|419692_421294_-|long-chain-fatty-acid--CoA-ligase
MTATLSLTSVLRESALRHPDKVGVVDGDNRVTYAELWQRSLRYAAALRELCPGPRPTVALLAPNTVEFPTTYYGALAAGCVVVPVHLLFTAPEMAHVLRDSGADLLVCHHALAAVGAAASAEAGVPLVTVGGAPSGGDAGIPADGAADGSTPVPSLDQLADTTTPLPVAETTAPEDPAVVLYTSGTTGEPKGAVLTHLNLVMNATISAFDANEVRHADVVLGCLPLFHTFGQTVSMNACFRAGGTLVLLARFHPDTAIDLMLREDVDVFHGVPTMYVALLAAASRHDRLPALRLCVSGGAALPVPVLEGFSTTFDAQIYEGYGLSETSPVATASQPRFGTRAGTVGHAIWGVEVEIAELEDPERIRLLGEGELGEIVVRGHNVFAGYLNRPQATEQVVVDGWFRTGDLGTKDADGFVRVVDRKGDVVIRGGYNIYPREVEDVLARHPSVRQVAVIGLPDPVYGEEVCAVVVAEEGGEPVTEETLVSWSRPLLGKHKYPRHVRFVDELPLGPSHKVLKRELRRRLAAQPGAEAG

Crispr_ID: CP025990_7

• CRISPR_ID: CP025990_7
• CRISPR_location: 418057-418284
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,cas4,cas3,cas5,cas7

Consensus repeat of CP025990_7

Consensus_repeat	Method
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CRISPRCasFinder
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CRT

spacers of CP025990_7

>7.1|418087|38|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGACGGTGCCTGCACCAGGCCCCGTGTCCCCGGTGCCC
>7.2|418155|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCCGCACGTACTCCATACTGAAAACGACAATCGC
>7.3|418220|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
AGGACACCTCGGCCCCGCAGATGGGGCACGTCCTG

CRISPR arrays and Neighbor proteins around CP025990_7

CRISPR arrays

The CRISPR arrays of CP025990_7

>merge|CP025990|7|418057-418284|PILER-CR,CRISPRCasFinder,CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAACGGACGGTGCCTGCACCAGGCCCCGTGTCCCCGGTGCCCGTCCTCATCGCTCCTACGAGGAGTTCCAACGCCCGCACGTACTCCATACTGAAAACGACAATCGCGTCCTCATCGCTCCTACGAGGAGTTCCAACAGGACACCTCGGCCCCGCAGATGGGGCACGTCCTGGTCCTCATCGCTCCTACGAGGAGTTCCAAC

>CP025990|7|6|418057-418284|PILER-CR
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GGACGGTGCCTGCACCAGGCCCCGTGTCCCCGGTGCCC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCCGCACGTACTCCATACTGAAAACGACAATCGC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	AGGACACCTCGGCCCCGCAGATGGGGCACGTCCTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC

>CP025990|7|6|418057-418284|CRISPRCasFinder
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GGACGGTGCCTGCACCAGGCCCCGTGTCCCCGGTGCCC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCCGCACGTACTCCATACTGAAAACGACAATCGC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	AGGACACCTCGGCCCCGCAGATGGGGCACGTCCTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC

>CP025990|7|6|418057-418284|CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GGACGGTGCCTGCACCAGGCCCCGTGTCCCCGGTGCCC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCCGCACGTACTCCATACTGAAAACGACAATCGC
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	AGGACACCTCGGCCCCGCAGATGGGGCACGTCCTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77238.1|418868_419294_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|187770
CP025990.1|AUS77245.1|427442_428261_-|lipase	unknown	unknown	gnl|CDD|238287
CP025990.1|AUS77247.1|429373_431002_-|malate-synthase-A	unknown	unknown	gnl|CDD|236432
CP025990.1|AUS77242.1|422776_423928_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|274215
CP025990.1|AUS77230.1|409990_410716_+|CRISPR-associated-protein-Cas6	unknown	unknown	gnl|CDD|224499
CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|187853
CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl|CDD|273860
CP025990.1|AUS77231.1|410712_412152_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77239.1|419692_421294_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341259
CP025990.1|AUS77244.1|425490_427332_+|DNA-helicase-RecQ	unknown	unknown	gnl|CDD|273594
CP025990.1|AUS81378.1|404739_405930_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
CP025990.1|AUS77240.1|421290_421755_-|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239534
CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl|CDD|366863
CP025990.1|AUS77243.1|424190_425099_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223489
CP025990.1|AUS77241.1|421941_422700_-|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl|CDD|187594
CP025990.1|AUS77246.1|428825_429404_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77229.1|406505_407789_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|238045

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	3.9e-56	185.3	0.0
CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1e-20	68.5	0.0
CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	3.5e-52	172.1	0.0
CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	9.3e-36	118.1	0.0
CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	6.6e-94	309.4	0.0
CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	3.2e-19	64.1	1.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	6.89138e-54
CP025990.1|AUS77245.1|427442_428261_-|lipase	gnl|CDD|238287	cd00519, Lipase_3, Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site. .	1.35491e-41
CP025990.1|AUS77247.1|429373_431002_-|malate-synthase-A	gnl|CDD|236432	PRK09255, PRK09255, malate synthase; Validated.	0
CP025990.1|AUS77242.1|422776_423928_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	2.28585e-160
CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl|CDD|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	4.72222e-55
CP025990.1|AUS77230.1|409990_410716_+|CRISPR-associated-protein-Cas6	gnl|CDD|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.83323e-13
CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.35232e-119
CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5	gnl|CDD|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	6.0735e-15
CP025990.1|AUS77239.1|419692_421294_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|341259	cd05936, FC-FACS_FadD_like, Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD. This subfamily of the AMP-forming adenylation family contains Escherichia coli FadD and similar prokaryotic fatty acid CoA synthetases. FadD was characterized as a long-chain fatty acid CoA synthetase. The gene fadD is regulated by the fatty acid regulatory protein FadR. Fatty acid CoA synthetase catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions.	0
CP025990.1|AUS77244.1|425490_427332_+|DNA-helicase-RecQ	gnl|CDD|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
CP025990.1|AUS81378.1|404739_405930_+|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	3.63729e-15
CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.03711e-22
CP025990.1|AUS77240.1|421290_421755_-|MaoC-family-dehydratase	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	1.39296e-70
CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein	gnl|CDD|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	8.60246e-46
CP025990.1|AUS77243.1|424190_425099_-|alpha/beta-hydrolase	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	1.092e-07
CP025990.1|AUS77241.1|421941_422700_-|3-oxoacyl-ACP-reductase-FabG	gnl|CDD|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.00974e-112
CP025990.1|AUS77229.1|406505_407789_-|XRE-family-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.42932e-08

Protein sequences

>CP025990.1|AUS77237.1|417681_417945_+|CRISPR-associated-endonuclease-Cas2
MYTILVYDTAAERNAGVLRTCRRYLRHQQRSVFEGELSAAQFVRLREELRQRIDADYDHILVYTFPPGTDPQRQAWGRPDDEPPDIL
>CP025990.1|AUS77236.1|416698_417679_+|subtype-I-B-CRISPR-associated-endonuclease-Cas1
MPAASRTYWLLNPCRLRRQDDSIRVEREGKPPAFVPIKDVRDIIALAEVDLNTSMISLLNKHRVAIHILSHYGDYAGSFLPAETSVSGTVALNQARIASDDGESLTIARSLVDTAAFNIRRVIDRKLLTRPYGVLTEALEAATTREQLMAAEGNFRRSAWEALDTKLPDWLQLDGRSRRPPRNAGNAVISFINGTVYARILTGLRLTPLHTGVAFLHASTQRHRHSLALDLAEVFKPLFAERILLRLANRKQLKKHHFDVGSNQAMLSEAGRKFIVQTVRDDLAESVNHRTLGRKVTYDELIYLDALALTRTCLEGTPYKPFRIWW
>CP025990.1|AUS77235.1|416201_416699_+|Dna2/Cas4-domain-containing-protein
MISADDVGGVHIKYLYHCRRQLWLYSRGFRPEQLSETVALGTAIHDISYSRFSPVDLGAATLDHLDNQLWVHEVKHSDKRREADRAQARHYCHQLTRVGVDVQGAVLHYRSPRKTERFPYTEEEHMHASEDIEQVVATIALPESPPRLPKSRCRGCSYSDYCWSV
>CP025990.1|AUS77234.1|413823_416205_+|CRISPR-associated-helicase/endonuclease-Cas3
MTEDLPHLWAKSPAKEATTGESLTEHSARTSAVVPLIRARIGVVDGIWDESWWPAVQLAALLHDGGKIDPGFQRQVRTNTRWGLRHEVLSLGFVDLLVTDQEVRRRVAAAVVTHHRPLHGDATRSILPDNLSQDQQALGQAFTVAEDDGTVRALAAWFADAAARVGLPVDRSRLGGLTRDDIRAGTLTLLRDLAEDWWYPGTEQGGLPWVLLQGVVTMADHVASAHGELLTGEPLRGYGDRVRVRLAAAGHRLTRAQEEATAAHHLLLVSPTGSGKTEGGLLWAEAAWRQVAEQRNALPRVFYVLPFLASINAMALRLQEEDGVEDVGVLHSRAGMFHLNELIEARAAGSDDRPEPTVDDAATALDHVNASRTHRELFRVTTPYQLLRAAFGGPGDSSTLADTVNSVFLFDELHAYEPRRLGMLLAMIRLWTQELGGRVGVLSATLPERFRRILRDTIAGRLDVVDGFAGVRHTPRHRLRIGGGHLTSPESVDRIAADLHAGQAVLVVANNVADALDLYDLLGPVAKEQGGEAVLLHSRFRNCDRAQKEKRILELFGTDRRSSRGLLVATQVVEVSLNVDFDVLHTSGAALEALLQRFGRVNRRGKRAPASVWVCEPEYRRRRGGGEETWADGVYDEVPTRLCWAALQNHDGETIDEADAQQWLNAIYDSPWGDTWEKEVLVSQERFDEDYLDFRSPFADREGLRKEFFATFDGVEAILSDDLADYQADRRQGEKGQGALLASRFLLPLPVHLSSSGHFDRRHGITVINGDYHPELGLKGIVRETRYQPGEIL
>CP025990.1|AUS77233.1|413167_413827_+|CRISPR-associated-protein-Cas5
MSVPALEVTFDASVASFRNPLYPGLQVGLPCPPPSTVGGLLAAAAGGWGQVPRDTRFALCCHAEGHGTDLETFHPLAEGVRQPSPVPKDRDYLWGVRLTVWLFEDLDRWYRRFRRPVWPLRLGRSQDLCSARAAWVDLREQPGRQGTALLVDRPDAVGTRLRLTTAISVDRARMRWDDYRHSSDAAAARGVLSDGWSTHDGQAVIPLPPTHPEVVEARS
>CP025990.1|AUS77232.1|412148_413171_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MTYLVGTLVLEIKAGAPNNGRGEDNVGKVKATRVGNRVFPYVSAQAVRRWWRDSLPPGEARSPVIRSGKGAKQQAHTQGRGDLYLDDDLFGYMVAIEKKSFNRDTVLAVGTAVSVAPRQVTHDFGTMSRGFEVGADPVIHEHEHYTGDLACPVLLDLARLGTFQLEGQGNRPDLNPDAAKEARVNGAEEIDFRFGQALRLPLAERRRRAAVLWRTLAELRGGAKQALHYGERSPALVILAPVKGGNNPFTRLLRHDLGETVVALDVLRAEMRAWEDELDGPVRIGWAPGYLERQRDAAERELKDLVDSGQVVFDHPRVVLRQLAAELEGGDLDSWFEDRS
>CP025990.1|AUS77231.1|410712_412152_+|hypothetical-protein
MTAADMRATSTGEPFLVELTAHPLQRVGAFALAVLAKESHPRRVSEDRFLRVWNRMTEDAVAATRETDAKQPGAFLLSASYALWPNSKMNIPSLRKLSADQRGQAVVEWRTPRPPESWPEAPCALCGRRACGFYGKVDVPLAMSTEYRNTTVVGHDGMPLCRTCLGSFYALPYACHFQGGRATITHAWDEDFLSFATRHQVEDTRKRIGRVSVTPSKWPAYVRESLLVNRIRAYGHPVRSDVSLIIFTNNNQEQELTEQRMDQPLVEWIHAVRQDKTSDPWNSLERACHSEKVPGAAALAGELVRSPRRLPAKVLRYLGPLLTSAPDTRDEIRQLVGALRSFVGKVLHVNDRELQEIEGLGKRTAALMMATRKKVKPFVVAYRKSTTFRKWFNDGAVEWLLWRDREELTSLIDTTEPFVTPTHLRWLFEPDEQAWLRRNLLFVAVIHELHSQGYRPDSDDTRSIEDTLHTDGEDKENDE
>CP025990.1|AUS77230.1|409990_410716_+|CRISPR-associated-protein-Cas6
MTTTAPGIPWAEVLRPGRGIVYQMLGDNAPALGAELHSAGFGPHRLVPVGCGAPRFPRARRQRGRYAAGGEGTLEFGSPLPEVIEALAAGLAGARVLDWGGVALRVQNVVSVPAPEFSDGSARLATTTPVVVKGPPARDAAGARLRSQRWLLPGEPEWDVFFVRNLRRKAETLGLDPEISLTEVWRVGPKRSFAVGQGDTVGAKVGAAVGVTLVGSPDTLAAVWSWGLGAANIAGFGAVET
>CP025990.1|AUS77229.1|406505_407789_-|XRE-family-transcriptional-regulator
MVLTSMGEAYAGVRQRRVRAAKGTSVKLEDDLIGTRIRQIRHWRGMTASSVAGPAGISRSYLSRIELGGRAVSSRSLLEALASALRVAPSALTSEPHKTLRRGDQSAHDVIQSLDSALTSAMPGERPEDTTPRPLPALAAAIDGVNAARHACDYPALADLAPRLVRELLVLYASGPHRRQAGEWLASTYQAIMDAAKALHGVGLPALAYTHVRTIAEDLDDPQLRGLGYWMRGQAFGPGRRREQVAFSAAAAGSLEPHIGEPGVLEAYGQVHLNAALGAVASGQHDVADAHVREARDAARRVSGPGSPWAGLWFGPTNVAVWSLVIASEKKDIGAVDRIAGQIDIDVIPYAGRRAAFYSEWGRAVLSETRSRERGLALLLKAEKLAPHRVRNHPLVRDAVSSLLVRSRREAGAGALRGLALRMGIAT
>CP025990.1|AUS81378.1|404739_405930_+|PucR-family-transcriptional-regulator
MRSRASAEAVAVVHHAARSLLSELPQLTDHLVALLREQEPAYRSAATDFDGLWREVHESLEHNIRSILAPRETRESARRCSWRIGAERAEQGLPLDALLHAFRLGGGVVWQGLVDATTRSDPDRVHLLVHVAADVWNFVDEHCGLLADAYRKVEGQLTRRREERLRALVGALLDGSTRLADVPAVAAALDLPQQARYAVVVVAGQGRAVLRDPGLRVGVPGTRIIWHTGVEEELGIVQLGDVAVADLAAALTVPRGCRVGVSPAVEELAAVGAARRFADTALRTCEDDAQVALLEDHLPSAMVVSCPELSAALTRRALGPVLDLDPPDRKVLLSTLEVWLDCDGSALRAGTRLFCHRNTVLNRLRRYEQLSGRSLNRQRDLLELALALEAQRLLGE
>CP025990.1|AUS77238.1|418868_419294_+|hypothetical-protein
MFGTRWRSGTGSGGCVFGAAGVVIGGGMTAQVDAALGALVRHGFVFRHAPGDRYVPWTLFGQRPRGAYGDYLHVSGPDDCLAARMRTSSQPAPSDVVWCEEGAFLDTVSALLSLPAPDVANAPRLATRRTAALWTPGMPLG
>CP025990.1|AUS77239.1|419692_421294_-|long-chain-fatty-acid--CoA-ligase
MTATLSLTSVLRESALRHPDKVGVVDGDNRVTYAELWQRSLRYAAALRELCPGPRPTVALLAPNTVEFPTTYYGALAAGCVVVPVHLLFTAPEMAHVLRDSGADLLVCHHALAAVGAAASAEAGVPLVTVGGAPSGGDAGIPADGAADGSTPVPSLDQLADTTTPLPVAETTAPEDPAVVLYTSGTTGEPKGAVLTHLNLVMNATISAFDANEVRHADVVLGCLPLFHTFGQTVSMNACFRAGGTLVLLARFHPDTAIDLMLREDVDVFHGVPTMYVALLAAASRHDRLPALRLCVSGGAALPVPVLEGFSTTFDAQIYEGYGLSETSPVATASQPRFGTRAGTVGHAIWGVEVEIAELEDPERIRLLGEGELGEIVVRGHNVFAGYLNRPQATEQVVVDGWFRTGDLGTKDADGFVRVVDRKGDVVIRGGYNIYPREVEDVLARHPSVRQVAVIGLPDPVYGEEVCAVVVAEEGGEPVTEETLVSWSRPLLGKHKYPRHVRFVDELPLGPSHKVLKRELRRRLAAQPGAEAG
>CP025990.1|AUS77240.1|421290_421755_-|MaoC-family-dehydratase
MRIFDSPAALLDATGDHLGPGPATVIDQERVDTFADVTDDHQWIHTDPTRAAHGPFGGTVAHGYLTLSLLPSFIRGLYRVRGARLIVNYGLNRVRFPAPLRTGDTVRATARLDQAHQVGDAVQVHLLVTIQADGADKPCCVAESLSRFYPEEEA
>CP025990.1|AUS77241.1|421941_422700_-|3-oxoacyl-ACP-reductase-FabG
MRGFTDTAAIVTGAAQGIGAATARRLAAEGAAVAVVDLNADRAAEVAADIERTGGRALALGCDVTDPDSVQTTTDHVVAEFGRLDILVNNAGITRDDLLFKMTLPDWNAVLTTNLTSMFLCTQAAQAHMVQARSGRIVNLSSRSALGNRGQSNYAAAKAGVQGLTATLALELGPFGIRVNAVAPGYVATDMTAATARRVGFEPEKHQERAAEQIPLRRVATPEEIASTITFLASDDASYVTGQTLYVNGGSR
>CP025990.1|AUS77242.1|422776_423928_-|acyl-CoA-dehydrogenase
MDLSLTPEHADLRQLARNFADDEIAPHAAEWDRRESLDLDLIPRMGELGFLGLTIPEEHGGSGGDHLAYYLVLEELGRADSSVRGVVSVSLGLVAATIARHGTPEQHQRWLPALCSGRALGCFALTEPGTGSDAGALTTRAVRDGDDWLITGAKTFITNGTWADVALLLARTSDDGSRGITAFLVPTASAGFHRREINDKLGLRAQATAELHLDGVRVPDTARLGEVGRGFPLAMSALGKGRVSVAAGCVGIAQASLDAALRYAGERHQFGKAIAGHQLVQRLLATTAVDTAAARLLVWQAADLLDRGQPHETAASMAKLFASEAAVRAADNAVQVFGGYGYVDEYPVSRYLRDARVTTLYEGTSQIQQLVIGRSLTGVAAFS
>CP025990.1|AUS77243.1|424190_425099_-|alpha/beta-hydrolase
MRSTLSRPTPPRSRLRRALTSAVLTLGLVAGSLAAAPAASGQENPYERGPAPTERSIEALRGPFSTSSTNVPRLAASGFGGGTIYYPTSTAEGTFGAVAISPGYTALESSISWLGHRLASQGFIVFTIDTITTLDQPASRGRQLLAALDHLVDHRSVRDRIDPTRLGVIGHSMGGGGTLEAASNRPSLKAAVPLTGWHLSKNWSDVQVPTLVVGAENDSIASVTLHSKPFYNSLPSTLNKAYLELAGASHFAPNISNTTIAKYTISWLKRFIDDDTRYEQFLCPAPSGDRDISEYRDTCPHS
>CP025990.1|AUS77244.1|425490_427332_+|DNA-helicase-RecQ
MAATDTGQDTRDALEVLRRVFGYDSFRDGQREIVDHVVDGGDALVLMPTGGGKSLCYQIPSLVRDGVGVVVSPLIALMQDQVDALTALGVRAGFLNSTQEPEERERVEEAFVDGRIDVLYLAPERLRLESTVRLLDRGTISLFAIDEAHCVAQWGHDFRPDYLLLSHLHERWPEVPRIALTATATEATRAEIVSRLDLGGARQFVASFDRPNIQYRIVPKNDPKRQLLQLLRTEHAGEAGIVYCLSRSSVERTAEFLVANDIPAVPYHAGLDGRTRAENQARFLREDGLVVVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPSTAWLAYGLPDVVQQRRLIDGSEGDDQHRARLVAHLDAMLALCETVECRRVRLLAYFGQHGEPCGNCDTCLSPPETWDGTVAAQKLLSTVSRLHRERRQRFGAGQVVDILLGRKTAKVIQHDHDTLSVFGIGTELSEAEWRAVTRQLLAQGLLAVQGEHGVLVLTEASGAVLRREREVPLRRDAARRAAGGSTRPVKRSGSAPVDLPAEAVPVFERLRAWRAATAKEQGVPAYVIFHDATLRQIAADSPSTLAELGGVSGVGENKLAKYGQAVLDTLAS
>CP025990.1|AUS77245.1|427442_428261_-|lipase
MAITALDHHETGYRLEHAYWLARAAKLAYSDESAIREAVGEWGFDRFRFLEGTPVTPLPIDHTQAFVAASDSMIIVAFRGTEPTQIRDWLTDANAPAGPGPDRRGLVHLGFSQALASVHPALLATLEEFRDNDQTLWFTGHSLGGALAQLAAAWLYFEDPNLLADGIYTFGQPRTCDRELATAYDGAIRARTHRFVNNNDVVPELPPEPFYRHVERVRYFDSQGRLQERTTLLGGAVDRLRGHTADPLSPGADALRDHPINRYLECLEKNLP
>CP025990.1|AUS77246.1|428825_429404_+|hypothetical-protein
MWETVRLVDVIDFPGGGGGGGGGRPGVPVGAVGVGWVVVPVPARPEPVRGPLAARRGCPLEELWGGGAGVYLAGLSAGGWRGRAPPSGTGRAGPGRGGVGDAPAWVRSGPAARRRLGRGGERVGGPVRRAPTRGGPPPSGRGTRWAVPGGLGMVGLGGFTGGSAVVGGGPPAGGGRGAGWGQGQRWVVRWWA
>CP025990.1|AUS77247.1|429373_431002_-|malate-synthase-A
MTTATRHTPFPTAGRVEIHGPLRDRYDEILTPEALDFLALLDNTFAADRRALLDRRRHRRARLTDGTETPHFLPETAAIRDDPTWRVPPPPPGLLDRRVEITGPPDRRMTVNALNSGAKVWMADFEDATAPTWDNIIGGQLNLHDAIRRRIDFTTDTGRRYRIAEDPATIVPRPRGWHLVEKHLRIDGRPVSASLVDFGLHVFHNATRLIQDGSGPYLYLPKLENHREARLWNEVFLLAQRALGLPPGTIRATVLIETITAAFEMDEILHELRDHAAGLNAGRWDYLFSLIRTLGGRGADVVLPDRARLTMTVPFMRAYTELLVRTCHRRGAHAIGGMAAVIPSRDPDANREALAQVRQDKDREATDGFDGSWVAHPALVPVCGEAFTAVLGDRPHQLHRTRDDVHVTADQLLDLGGAGREVTREGVRSNVGVCLRYLDAWLRGSGAVAIHGLMEDAATAEIARAQLWQWIHTATTLTDGTTVTRDLVGDALRAERDVIRAENPEATRLDAAVDILTATALGPTMPDFLTPHAYAHHLTTHR

Crispr_ID: CP025990_8

• CRISPR_ID: CP025990_8
• CRISPR_location: 478656-479050
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of CP025990_8

Consensus_repeat	Method
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	CRISPRCasFinder
GGCTCACCCCCGCTTGCGCGGGGCTTTC	PILER-CR
GGCTCACCCCCGCTTGCGCGGGGCTTTC	CRT

spacers of CP025990_8

>8.1|478685|32|CP025990|CRISPRCasFinder
GACAACGGCCGCGCGGCCAGCTCGACAAACCC
>8.2|478746|32|CP025990|CRISPRCasFinder
CGCGGCCTGCTGCTGAGCTGGCCACTCGAAAG
>8.3|478807|32|CP025990|CRISPRCasFinder
GCGATCTCACCGATCCCGCGCCGCTGGTGGAT
>8.4|478868|32|CP025990|CRISPRCasFinder
AGGACTTCACCGCCGGAGAGAGCACGGTCGTC
>8.5|478929|32|CP025990|CRISPRCasFinder
GCGCCCCGGACGCGGACGTCCTCGAACTCCTG
>8.6|478990|32|CP025990|CRISPRCasFinder
TGCGGCCGTGATGGTCGCCGGCGGTGGACTGG
>8.7|478685|33|CP025990|PILER-CR,CRT
GACAACGGCCGCGCGGCCAGCTCGACAAACCCC
>8.8|478746|33|CP025990|PILER-CR,CRT
CGCGGCCTGCTGCTGAGCTGGCCACTCGAAAGC
>8.9|478807|33|CP025990|PILER-CR,CRT
GCGATCTCACCGATCCCGCGCCGCTGGTGGATC
>8.10|478868|33|CP025990|PILER-CR,CRT
AGGACTTCACCGCCGGAGAGAGCACGGTCGTCC
>8.11|478929|33|CP025990|PILER-CR,CRT
GCGCCCCGGACGCGGACGTCCTCGAACTCCTGA
>8.12|478990|33|CP025990|PILER-CR,CRT
TGCGGCCGTGATGGTCGCCGGCGGTGGACTGGC

CRISPR arrays and Neighbor proteins around CP025990_8

CRISPR arrays

The CRISPR arrays of CP025990_8

>merge|CP025990|8|478656-479050|CRISPRCasFinder,PILER-CR,CRT
GGGCTCACCCCCGCTTGCGTGGGGCTTTCGACAACGGCCGCGCGGCCAGCTCGACAAACCCCGGCTCACCCCCGCTTGCGCGGGGCTTTCCGCGGCCTGCTGCTGAGCTGGCCACTCGAAAGCGGCTCACCCCCGCTTGCGCGGGGCTTTCGCGATCTCACCGATCCCGCGCCGCTGGTGGATCGGCTCACCCCCGCTTGCGCGGGGCTTTCAGGACTTCACCGCCGGAGAGAGCACGGTCGTCCGGCTCACCCCCGCTTGCGCGGGGCTTTCGCGCCCCGGACGCGGACGTCCTCGAACTCCTGAGGCTCACCCCCGCTTGCGCGGGGCTTTCTGCGGCCGTGATGGTCGCCGGCGGTGGACTGGCGGCTCACCCCCGCTTGCGCGGGGCTTTC

>CP025990|8|7|478656-479050|CRISPRCasFinder
GGGCTCACCCCCGCTTGCGTGGGGCTTTC	GACAACGGCCGCGCGGCCAGCTCGACAAACCC
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	CGCGGCCTGCTGCTGAGCTGGCCACTCGAAAG
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	GCGATCTCACCGATCCCGCGCCGCTGGTGGAT
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	AGGACTTCACCGCCGGAGAGAGCACGGTCGTC
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	GCGCCCCGGACGCGGACGTCCTCGAACTCCTG
AGGCTCACCCCCGCTTGCGCGGGGCTTTC	TGCGGCCGTGATGGTCGCCGGCGGTGGACTGG
CGGCTCACCCCCGCTTGCGCGGGGCTTTC

>CP025990|8|7|478657-479050|PILER-CR
GGCTCACCCCCGCTTGCGTGGGGCTTTC	GACAACGGCCGCGCGGCCAGCTCGACAAACCCC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	CGCGGCCTGCTGCTGAGCTGGCCACTCGAAAGC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	GCGATCTCACCGATCCCGCGCCGCTGGTGGATC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	AGGACTTCACCGCCGGAGAGAGCACGGTCGTCC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	GCGCCCCGGACGCGGACGTCCTCGAACTCCTGA
GGCTCACCCCCGCTTGCGCGGGGCTTTC	TGCGGCCGTGATGGTCGCCGGCGGTGGACTGGC
GGCTCACCCCCGCTTGCGCGGGGCTTTC

>CP025990|8|7|478657-479050|CRT
GGCTCACCCCCGCTTGCGTGGGGCTTTC	GACAACGGCCGCGCGGCCAGCTCGACAAACCCC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	CGCGGCCTGCTGCTGAGCTGGCCACTCGAAAGC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	GCGATCTCACCGATCCCGCGCCGCTGGTGGATC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	AGGACTTCACCGCCGGAGAGAGCACGGTCGTCC
GGCTCACCCCCGCTTGCGCGGGGCTTTC	GCGCCCCGGACGCGGACGTCCTCGAACTCCTGA
GGCTCACCCCCGCTTGCGCGGGGCTTTC	TGCGGCCGTGATGGTCGCCGGCGGTGGACTGGC
GGCTCACCCCCGCTTGCGCGGGGCTTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77279.1|471864_472983_-|gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
CP025990.1|AUS81382.1|476420_477053_-|DUF385-domain-containing-protein	unknown	unknown	gnl|CDD|211538
CP025990.1|AUS77276.1|466121_467126_-|NAD-dependent-epimerase/dehydratase	unknown	unknown	gnl|CDD|366597
CP025990.1|AUS77278.1|471619_471895_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77286.1|480626_481190_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
CP025990.1|AUS77277.1|467157_468381_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|378005
CP025990.1|AUS77280.1|472979_473768_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|366542
CP025990.1|AUS81381.1|468541_471358_-|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS77291.1|485718_486759_-|myristoyl-transferase	unknown	unknown	gnl|CDD|223787
CP025990.1|AUS77285.1|479895_480630_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
CP025990.1|AUS81383.1|487636_488377_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
CP025990.1|AUS77292.1|486800_487640_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
CP025990.1|AUS77290.1|484958_485735_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
CP025990.1|AUS77288.1|482600_483461_+|DNA-polymerase-subunit-beta	unknown	unknown	unknown
CP025990.1|AUS77289.1|483484_484801_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
CP025990.1|AUS77287.1|481247_481568_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77284.1|479125_479899_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|372253
CP025990.1|AUS77281.1|474013_475300_-|oxidoreductase	unknown	unknown	gnl|CDD|223745
CP025990.1|AUS77283.1|477632_478130_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240041
CP025990.1|AUS77282.1|475179_476013_-|trehalose-utilization-protein-ThuA	unknown	unknown	gnl|CDD|153236

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77279.1|471864_472983_-|gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.00318e-53
CP025990.1|AUS81382.1|476420_477053_-|DUF385-domain-containing-protein	gnl|CDD|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	1.91817e-08
CP025990.1|AUS77276.1|466121_467126_-|NAD-dependent-epimerase/dehydratase	gnl|CDD|366597	pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilize NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.	1.6317e-44
CP025990.1|AUS77280.1|472979_473768_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	2.34525e-15
CP025990.1|AUS77286.1|480626_481190_-|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.78352e-15
CP025990.1|AUS77277.1|467157_468381_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|378005	pfam08484, Methyltransf_14, C-methyltransferase C-terminal domain. This domain is found in bacterial C-methyltransferase proteins. This domain is found C-terminal to methyltransferase domains such as pfam08241 or pfam08242. But this domain is not a methyltransferase.	1.14204e-73
CP025990.1|AUS81381.1|468541_471358_-|LuxR-family-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	9.52512e-15
CP025990.1|AUS77291.1|485718_486759_-|myristoyl-transferase	gnl|CDD|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	3.37168e-42
CP025990.1|AUS77285.1|479895_480630_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.74311e-67
CP025990.1|AUS81383.1|487636_488377_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	7.33468e-118
CP025990.1|AUS77292.1|486800_487640_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	3.86853e-58
CP025990.1|AUS77289.1|483484_484801_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.36176e-120
CP025990.1|AUS77290.1|484958_485735_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	3.94831e-53
CP025990.1|AUS77284.1|479125_479899_-|ABC-transporter-permease	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	3.68811e-08
CP025990.1|AUS77281.1|474013_475300_-|oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.33026e-46
CP025990.1|AUS77283.1|477632_478130_-|NUDIX-domain-containing-protein	gnl|CDD|240041	cd04685, Nudix_Hydrolase_26, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	2.11545e-29
CP025990.1|AUS77282.1|475179_476013_-|trehalose-utilization-protein-ThuA	gnl|CDD|153236	cd03142, GATase1_ThuA, Type 1 glutamine amidotransferase (GATase1)-like domain found in Sinorhizobium meliloti Rm1021 ThuA (SmThuA). Type 1 glutamine amidotransferase (GATase1)-like domain found in Sinorhizobium meliloti Rm1021 ThuA (SmThuA). This group includes proteins similar to SmThuA which plays a role in a major pathway for trehalose catabolism. SmThuA is induced by trehalose but not by related structurally similar disaccharides like sucrose or maltose. Proteins in this group lack the catalytic triad of typical GATase1 domains: a His replaces the reactive Cys found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. S. meliloti Rm1021 thuA mutants are impaired in competitive colonization of Medicago sativa roots but are more competitive than the wild-type Rml021 in infecting alfalfa roots and forming nitrogen-fixing nodules.	4.89631e-119

Protein sequences

>CP025990.1|AUS77283.1|477632_478130_-|NUDIX-domain-containing-protein
MTASTSTVTPRIGARVLLLDPADRVLLIHALDPAEPDHHWWELPGGGLDDGEDLRDAARREAAEETGIMLPTLGRELWVRESRFRYKGRDHHRIEHVFLGRTQGNAPQVAPRPTENEKAGLIGRRWWPADELRQCRDKLLPAELPTLLDDLLSGRFSTAPLTLID
>CP025990.1|AUS81382.1|476420_477053_-|DUF385-domain-containing-protein
MIVLGGVLRVRTEDDGELVVHPGEVVHLPANSTNEFVAEEEVTACYVAGPPDVYARHADDPASHRWEPQPASRGTGTPDEAAVRRALDSDVLVDITTTGRRSGLPRRLEIWLYRSGGRFFLTGYPEDRPRDWYRNLLADPRLTVHLKESVVVDLPATAVEVTDAVDRRRVLDDILDQLSRPDNPQGLSEELDRAGWQARSPLLEITGLTG
>CP025990.1|AUS77282.1|475179_476013_-|trehalose-utilization-protein-ThuA
MSAVPDHRPAADTPGDAPGPPRITVWNENVHERTQPEVAERYPRGIHGAVAAAIADHLGPAASIRTATLDEPGQGLPPEVLDTTDVLVWWGHLAHDRVDDALVERVRERVLGGMGLVVLHSGHFSKVFTRLLGTTCALRWRNGDDRELVWTVDPRHPIAEGVPSPLVIDRQEMYGEFFDIPAPDELVFVSSFSGGEVFRSGVTFRRGHGRIFYFSPGDQDYPVYHHPDVRRVIANGVRWARPDRPVGSPPRLRRSPVGWWDDEPATHSGAASPGADR
>CP025990.1|AUS77281.1|474013_475300_-|oxidoreductase
MGEAGPAGRVPAEVAPLPGGLVGRRAGDTLGGRVPGCGPMTVGAFRTVDHHGPLRAVVVGAGAMGRAWLNTVDASPTVDLVGVVDLDPNAATAALSACGVPPVPVSTSLSALAEATLPDLVVDVTIPSAHYSVTREALDLGLAVLGEKPLAATLAEAIGLVVAAERAGRLFAVSQNRRHSPGLAALRRQVWTLGAVGTVSTEFFRAPRFGGFREEMEHPLLLDMAIHPFDAARYLVGGDPVTVWCEEFNPHWSWYRGDAAATAIFEMTGGVRYLYTGSWCAPGLETSWNGRWRVSGRHGAAVWDGEGEPVVEHAVPVAGAAEAAAESRARGWGSPSPTDIAGSLADFEHALRTGLAPSTVAADNLLSLAMVHGAIASAGTGTRVVIADLLAEAHRDAVDGADEDLRPALRDWRPPTPGGNGGGSGAGT
>CP025990.1|AUS77280.1|472979_473768_-|sugar-phosphate-isomerase/epimerase
MSDPTSPILSTPPAVQLYTVREQLAADRVGVLAALAGFGYGAVEPFDVLTDAPGLRDDLDAAGLAVCAVHAPVLSEDVDALFDGARTVGADTVIVPVAPPERFGDRDAVTALAAELNAVASRAADAGLRLGYHNHEFEFTDVDGTPALVVLADALAPEVVLEVDTYWAAVAGQDVPALLRRLGDRVRYLHVKDGPVTRTDPMTAVGAGRMPVAEVLTANPAVEWRVVELDDCATDVLAAVGDSLDWLRDNGFAHPAGGGSDR
>CP025990.1|AUS77279.1|471864_472983_-|gfo/Idh/MocA-family-oxidoreductase
MTAPDPVAPLGVAVVGCGSISDQYLTNLTSFPEVSVLFCADLDVDRAAAQAARYGVPASGTFGQALEHPGVELVVNLTVPAAHVEVASAALEAGLHVWNEKPLTLDLEDGRALVAQAGRVGRRLGCAPDTVLGTGFQAARRLIDAGAIGTPLTALALVQEPGPDRWHPNPAFLFQRGAGPLFDLGPYYLTVLASLFGPAHRVGAVGRQALTTRRIVAGDRAGTEFRVEVPTHVSALVEYAGGPAATLLFSFDSPLRRHGFVEVTGTEATLALPDPNHFAGEVRIRDRGDEEWRVAAPPVPSAGRGLGVVDMVRSLRAGTPHRASGELGLHVLELMTAIERSAAAGEFDTVRGSFPMPEPLPPGWAPGTATGS
>CP025990.1|AUS77278.1|471619_471895_-|hypothetical-protein
MGARDGHGELTAAEDTPAACTVREPGVSSATTGRYIGFEIPSTFVAAPGTATMTTRLPRVVSLPTNGPVTVRSGSRARALTARESEHNCFA
>CP025990.1|AUS81381.1|468541_471358_-|LuxR-family-transcriptional-regulator
MDALHSLYVESTTGTGKLVLVSGGLASGKTELLHAFTRYAVEAGALVLTAGGSRAERSVQGGLIDQLFHGSALPATVVDHVSRLVVPDTSDAEDVGADIRHVGVHAMHEICAVLLELAREKPLVIAVDDVQFADSSSLQFLLYLRRRINSARLLIVLVEWERPQPTLPVFHAEVTRRRHHRIRLRPLPPARIADMLATATSEQDARLLAPCYHRLTGGNPLLVNALVDDHLASDPTERVDQDGRPRPVVGTAFGQAVLACLHRWEPRLLDVARAVAVLGAHQTPLLVGRLAGTTSAEADLVLEILTRAGLLEDGRFRHPAAELAVAESLSGDHRASLHVRAAELLYQRGVGAVEVARHFAAADRAAGAWSVGVLREAAEQALIGDDVATAVHLLELALEVPEGDAADRLAVTRVLVRALWRVNPSAASRYLEPMLRAVEAGELGGRDAVFVVSHDLWNGDTDSALARLERFAGKPGLLDDQTAAELDVAYQWFHGSPPARERPQGEAAPSTDDPWVDATQRLMTAWTQGCDPATMASAEHVLRSCRLGETTLEVVATALLVLVHGDQPATAARWCRQLLDEADRRGAVTWQAVLGGIESDVALRRGDPEAAVALARTALTRLPPRSWGVLIGWPLTTLLLADTALGRVEDAAHTLRQRVPDRMFATLFGVRYLHARGHHYLATDRLLAAISDFQACGRIVRGWDVDVPMLVPWRSDLAEANRQLGRLGVARDLARQQLDRSAGLDQRTRAITLRVLAASSDPADRAALLEEAVRCLEEAGDTFLLRAVRADLAAAQRSRAEPTRGGDAPPAGTRTAGGTRAEHPPTTADDGRSSHDTGPEDPAEDAGASPSTSGNEPRAADLAVAALSDSERRVAELAALGCTNREISARLYVTVSTVEQHLTRVYRKLGVRCRGDLPAGLRAPEAEADGPGPAREGP
>CP025990.1|AUS77277.1|467157_468381_-|class-I-SAM-dependent-methyltransferase
MPATPCRVCSGPVREFFDFGEQPLSDAFPLPDQLDGEFSFRLAIGCCESCSMVQLMEEVPRDRMFHEDYPYLSNGSAVMRDHFRAVASRFLRDELAGPDPFIVELGCNDGTMLRTVADAGVRHLGVEPSGGVADLAAARGVRVDKRFFEAETARDILAADGSADVIYAANTLCHIPYIDSILRGVDELLAPSGVFVFEDPYFAEIVRRTSFDQIYDEHFFFFTARSVRAMAARHGLELVDVEELPVHGGEVRYTLARTGAREISPAVGALIERETRSGLTDPTTLDAFAARVNQIRTDLLAFLRAEKAAGRPVVGYGATAKSATVLNFCGIGPDLISHVFDTTPAKQGRLTPGSHIPVRPAEEFADPYPAHAVLFAWNHAEEILAKETAFREAGGRWVLYVPELHVR
>CP025990.1|AUS77276.1|466121_467126_-|NAD-dependent-epimerase/dehydratase
MPASHIPLVAVLGASGFVGSAVAARLASRPIRLRLVARRPSTVPAGQAHVEVRTADLTEPGAVQDAVAGADAVVHLPLHTAGGTYRAAETDPAGERVNLGTARDLVAALRRRPPGQGPPPVVVFPGSTSQVGPPRTPLLDGTEADRPATEYDRQKCAVEEDLRAATAAGVLRGVTLRLPTVFGAPAAPEAVDRGVVTAMVRRALAGQPLTLWGDGRVRRDLLHVTDVAAAIALSLDRADALAGGRWLLGSGTGVSLRTLFELVAEVVAEHTGRPPVPVTSVPVPAQATEMDGRDLVADPAAFRAATGWTAAVPPRAGIAGIVSAQLAATPGGSG
>CP025990.1|AUS77284.1|479125_479899_-|ABC-transporter-permease
MNNFRGACWVEIHKASAARPLWITGGVFVVGLALLGCGLVLAVSTGNDQVVDRLGAAADLDGWPLLFTIVTQIAAAGGLLAFGIALSWSFGREFTDGTVLGLLASPTTRSVVVLAKLLTHLLWVCAVALVSVGALFLVGILLGLGPVNGDVLADFTRLVLLLVLTGAVVVPTSLVATLGRGALPGIGAAIALIVVSQVAAIVQPATAAWLPFATPAIWALFPEVVGMAQLGLVIATSAVFCGLTVHVWNRLELDRGV
>CP025990.1|AUS77285.1|479895_480630_-|ABC-transporter-ATP-binding-protein
MTALLEVTGAVRSYSPGVGVRGVTLTVEEGEVHALVGLNGAGKTTLMRLILGIARLRSGDIRIAGTPVARMTGSRWRCVGHMLDRPFAYPELTAQRNMLVAARLRGLPASTAAEAARKALDDAGLGDYAAVRAGRLSQGNRQRLGVAVAMLDEPRLLVLDEPTNALDPAGVIDLRERLRRRAARGAGVLVSSHHLDEVARIAHRITVMNRGEIAGTLDPGGTDLERALFDLVLSDDERRNRERV
>CP025990.1|AUS77286.1|480626_481190_-|TetR-family-transcriptional-regulator
MSVATVSKRERTLALLTERALALFEEQGFDQTSVVQIAASAGVSEMTFFRHFGSKEQAVLVDPFDPVIARAIGQRPLGEAALLRAVRGVRGALSGLDDAELGMVRRRVRIIASTLTLRVALAKQNEETAAAIQQQLISDGTDPRAARAAAAALLGALSAGLFEWAENEGTTLVEAIETALSVLEVGA
>CP025990.1|AUS77287.1|481247_481568_-|hypothetical-protein
MDTLPERQGIEGNDQEKGWLEGLTDYLVALAGTARWLGCGLEEVRRLLASAATAVARLVGVVGATCPRAPGCEPALRSGGMVHAATHTVAVIRSFVPAATALAAPR
>CP025990.1|AUS77288.1|482600_483461_+|DNA-polymerase-subunit-beta
MPHTEPTALARRIDRFREAAHAEPRLDGVLLYGSWTLGEADAYSDVEAYLFVRDADVADFDGVEFAARLGPVAYSYENQFGVLTVVFDDLMRGEFHVTASGAGVEQVRGWRGMIHLPDTERAVVLDRDGRLTSAARTLAEFQPPEPVGTASHLVGELTNWTLMEAHLLARGETARAHAWAQFMVAPAQLKLCRLLRDSTRHWLTPSRAVEQDLPAADVERYRATTSAAEPASVLAAAVRSWRWTRELAAEAEARWSISVPTELHGRIAALLADLEAGAGWPGPAVG
>CP025990.1|AUS77289.1|483484_484801_-|HlyC/CorC-family-transporter
MDSVATNLALVLLFVFAGGYFAASEIALVSLRDSQVDRLAATRGNRGKRLARLRSDPNRFLSAVQIGVTFTGFFASGYGGATIAVRLEPYLADWGLPAGLAATLALVLVTLFVSYLSLVLGELAPKRLALQKSEGVALFTAGVLDRLATVFRPLIWLLSRSTNAVVRLMGIDPQAAEEKVGEEELRDMVRTNEQLTVEERRLLDDAFAVGDRVLSEVMIPRTEVEFLDADLPLPDAVRLMRGKPHSRYPVIRESPDDVVGFVHVRDLLAVVDGEDPQGRTLADIARPVAAFPGSKPVLAALSQMRRKGGHLAMVIDEYGGTDGIVTVEDLVEEVVGEIYDEYDPGAVPSRRSPEGSVEVDGLLHRTEVEEQTGLTLPDGPFDTLAGYVVALFNRLPREGDSVEALHHRFTVRALDGRRVSRILVTPLRRSRPAEEDED
>CP025990.1|AUS77290.1|484958_485735_-|ABC-transporter-permease
MSSTTERRDRALPLLVGAASLAGGVGLWWALAAFSGLPSYVLPSPGQLVTRAVSLWQAGGLSIHLQQTLAEVLQGVALGSVIGIALAVLFVRVGWIERLLMPIIVVIQVTPKISIAPLIVLWLGLGIGSKITLITLVTFYPVLINMVGKLRGMPSTMHDLADVLNIRRGRRALLIDLPYSLPALAAGLRVGVLQAVTAAVIGEFIGAQAGLGYLEKQAQDNDDIQVVMICLILLSAIGWALYTLVGLIERKLTERFGG
>CP025990.1|AUS77291.1|485718_486759_-|myristoyl-transferase
MSPSPRSLRGVAALGLAAALGGVAACSPADNAGTTTGGDEGTTSVTVQIDGAAVPYYAPLYEAVEQGYFADHGLDVEFTYANGADIVQNVAAGNVDFGFPNGDSVITAYGSGVRTNVVHTTYQKGIGALLFANDSGIETPADLEGRSVAVTDLGSPNYAQLQAMLDSADLTVDDIDLRTIGTGAIVQALQSGEVDAIVFSRLRYFALQNAGMDVGQILSDEYLPSFGNILVTSPDTVENTPEVVASFTAALDEALQYTIDHIDESTAMSIEKYAPTFEGQEDEISEVLRDVYAAELWQSADTEENGFGHGNLDRWQEAIDSQAEFELIDEAFDAADLVRDHRELDN
>CP025990.1|AUS77292.1|486800_487640_-|ABC-transporter-permease
MSTAEITTGAATPPPAPGGNRPGGGPFGKGTPLRRITVAAAYLAVVLLAWQLYVTLADVPSYLLPDPLSVGDALWRLASSGELWPHLGYTVRNIAVGLGAGIVIGSLLGWVIASFRTVRLILAPYVVILQAAPKIALAPLLVLWFGLGLGSQLALIVMLAFFPMMIAMMLGLGEVTDDQRALGRVLNLGPARFFRLVQLPTALPALFAGARIAVIDAMTGAFLAEYISAQQGLGFLMVQGRSTYDTPQLIAAVVLTVVVGLTGFALVSLVERRALPWRR
>CP025990.1|AUS81383.1|487636_488377_-|ABC-transporter-ATP-binding-protein
MLEIRGVSKEYVSVKGASVRALDDVNLDIGDGEIIAIIGPSGCGKSTLLRMVAGLDTDYEGTIEWTRAPRPGRDIGFVFQEPALLPWRTVARNVSLGIEVQKDRSDLPTDRVDQLLELVGLRDFAKSYPKELSGGMRQRVAIVRALAYDPRILLMDEPFGALDAITRDKLHDDILRIWAATRKTIVFVTHSVEEAAYLADRVVVMSPRPGRLRSVHQVPLDRNRDAATRQLPVFAEFAGMLRGELA

Crispr_ID: CP025990_9

• CRISPR_ID: CP025990_9
• CRISPR_location: 481652-482209
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of CP025990_9

Consensus_repeat	Method
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder
GTTGGAACTCCTCGTAGGAGCGATGAGGACC	CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR

spacers of CP025990_9

>9.1|481682|36|CP025990|CRISPRCasFinder
CCGGGCACACCACGCCCTCGTCCGGCGCGTCGACTT
>9.2|481748|35|CP025990|CRISPRCasFinder,PILER-CR
CAGCAGATCTTCCACCTCCGCCGCACCGACCGCTG
>9.3|481813|35|CP025990|CRISPRCasFinder,PILER-CR
CACGCCACTGACGGCTACCCGGTGGAGGGAGTCGC
>9.4|481878|39|CP025990|CRISPRCasFinder,PILER-CR
TGGCTTCCAGTTCGGCCAAGACGTCGTCGGCGGCCGCGT
>9.5|481947|37|CP025990|CRISPRCasFinder,PILER-CR
GGTGACAGCGGATTTGTCCGGGGCCTGTGGTATGGCG
>9.6|482014|37|CP025990|CRISPRCasFinder,PILER-CR
CGTTCGAACTGCCAGCGCTCCATGCCCCCTGGCTCAG
>9.7|482081|35|CP025990|CRISPRCasFinder,PILER-CR
CTGCGCGAACTCGGCCTCCTCCCTCCCGCGCCCGC
>9.8|482146|33|CP025990|CRISPRCasFinder,PILER-CR
CCGTGGTCGGACGTGGTGTCGATCGGCATGCTT
>9.9|481683|35|CP025990|CRT
CGGGCACACCACGCCCTCGTCCGGCGCGTCGACTT
>9.10|481749|34|CP025990|CRT
AGCAGATCTTCCACCTCCGCCGCACCGACCGCTG
>9.11|481814|34|CP025990|CRT
ACGCCACTGACGGCTACCCGGTGGAGGGAGTCGC
>9.12|481879|38|CP025990|CRT
GGCTTCCAGTTCGGCCAAGACGTCGTCGGCGGCCGCGT
>9.13|481948|36|CP025990|CRT
GTGACAGCGGATTTGTCCGGGGCCTGTGGTATGGCG
>9.14|482015|36|CP025990|CRT
GTTCGAACTGCCAGCGCTCCATGCCCCCTGGCTCAG
>9.15|482082|34|CP025990|CRT
TGCGCGAACTCGGCCTCCTCCCTCCCGCGCCCGC
>9.16|482147|32|CP025990|CRT
CGTGGTCGGACGTGGTGTCGATCGGCATGCTT

CRISPR arrays and Neighbor proteins around CP025990_9

CRISPR arrays

The CRISPR arrays of CP025990_9

>merge|CP025990|9|481652-482209|CRISPRCasFinder,CRT,PILER-CR
GTTGTGGTTCCTCGTAGGAGCGATGAGGACCCGGGCACACCACGCCCTCGTCCGGCGCGTCGACTTGTTGGAACTCCTCGTAGGAGCGATGAGGACCAGCAGATCTTCCACCTCCGCCGCACCGACCGCTGGTTGGAACTCCTCGTAGGAGCGATGAGGACCACGCCACTGACGGCTACCCGGTGGAGGGAGTCGCGTTGGAACTCCTCGTAGGAGCGATGAGGACTGGCTTCCAGTTCGGCCAAGACGTCGTCGGCGGCCGCGTGTTGGAACTCCTCGTAGGAGCGATGAGGACGGTGACAGCGGATTTGTCCGGGGCCTGTGGTATGGCGGTTGGAACTCCTCGTAGGAGCGATGAGGACCGTTCGAACTGCCAGCGCTCCATGCCCCCTGGCTCAGGTTGGAACTCCTCGTAGGAGCGATGAGGACCTGCGCGAACTCGGCCTCCTCCCTCCCGCGCCCGCGTTGGAACTCCTCGTAGGAGCGATGAGGACCCGTGGTCGGACGTGGTGTCGATCGGCATGCTTGTTGGAACTCCTCGTAGGAGCGATGAGGACC

>CP025990|9|8|481652-482208|CRISPRCasFinder
GTTGTGGTTCCTCGTAGGAGCGATGAGGAC	CCGGGCACACCACGCCCTCGTCCGGCGCGTCGACTT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CAGCAGATCTTCCACCTCCGCCGCACCGACCGCTG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CACGCCACTGACGGCTACCCGGTGGAGGGAGTCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	TGGCTTCCAGTTCGGCCAAGACGTCGTCGGCGGCCGCGT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GGTGACAGCGGATTTGTCCGGGGCCTGTGGTATGGCG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CGTTCGAACTGCCAGCGCTCCATGCCCCCTGGCTCAG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CTGCGCGAACTCGGCCTCCTCCCTCCCGCGCCCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCGTGGTCGGACGTGGTGTCGATCGGCATGCTT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

>CP025990|9|8|481652-482209|CRT
GTTGTGGTTCCTCGTAGGAGCGATGAGGACC	CGGGCACACCACGCCCTCGTCCGGCGCGTCGACTT
GTTGGAACTCCTCGTAGGAGCGATGAGGACC	AGCAGATCTTCCACCTCCGCCGCACCGACCGCTG
GTTGGAACTCCTCGTAGGAGCGATGAGGACC	ACGCCACTGACGGCTACCCGGTGGAGGGAGTCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGACT	GGCTTCCAGTTCGGCCAAGACGTCGTCGGCGGCCGCGT
GTTGGAACTCCTCGTAGGAGCGATGAGGACG	GTGACAGCGGATTTGTCCGGGGCCTGTGGTATGGCG
GTTGGAACTCCTCGTAGGAGCGATGAGGACC	GTTCGAACTGCCAGCGCTCCATGCCCCCTGGCTCAG
GTTGGAACTCCTCGTAGGAGCGATGAGGACC	TGCGCGAACTCGGCCTCCTCCCTCCCGCGCCCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGACC	CGTGGTCGGACGTGGTGTCGATCGGCATGCTT
GTTGGAACTCCTCGTAGGAGCGATGAGGACC

>CP025990|9|8|481718-482208|PILER-CR
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CAGCAGATCTTCCACCTCCGCCGCACCGACCGCTG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CACGCCACTGACGGCTACCCGGTGGAGGGAGTCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	TGGCTTCCAGTTCGGCCAAGACGTCGTCGGCGGCCGCGT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GGTGACAGCGGATTTGTCCGGGGCCTGTGGTATGGCG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CGTTCGAACTGCCAGCGCTCCATGCCCCCTGGCTCAG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CTGCGCGAACTCGGCCTCCTCCCTCCCGCGCCCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCGTGGTCGGACGTGGTGTCGATCGGCATGCTT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77279.1|471864_472983_-|gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
CP025990.1|AUS77294.1|490519_491323_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
CP025990.1|AUS77287.1|481247_481568_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77280.1|472979_473768_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|366542
CP025990.1|AUS77286.1|480626_481190_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
CP025990.1|AUS81382.1|476420_477053_-|DUF385-domain-containing-protein	unknown	unknown	gnl|CDD|211538
CP025990.1|AUS77293.1|489512_490523_+|dihydroorotate-dehydrogenase	unknown	unknown	gnl|CDD|240091
CP025990.1|AUS77291.1|485718_486759_-|myristoyl-transferase	unknown	unknown	gnl|CDD|223787
CP025990.1|AUS77285.1|479895_480630_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
CP025990.1|AUS81383.1|487636_488377_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
CP025990.1|AUS77292.1|486800_487640_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
CP025990.1|AUS81384.1|488823_489516_+|phosphorylase	unknown	unknown	gnl|CDD|350167
CP025990.1|AUS77295.1|491322_491808_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77289.1|483484_484801_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
CP025990.1|AUS77284.1|479125_479899_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|372253
CP025990.1|AUS77290.1|484958_485735_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
CP025990.1|AUS77288.1|482600_483461_+|DNA-polymerase-subunit-beta	unknown	unknown	unknown
CP025990.1|AUS77281.1|474013_475300_-|oxidoreductase	unknown	unknown	gnl|CDD|223745
CP025990.1|AUS77283.1|477632_478130_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240041
CP025990.1|AUS77282.1|475179_476013_-|trehalose-utilization-protein-ThuA	unknown	unknown	gnl|CDD|153236

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77279.1|471864_472983_-|gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.00318e-53
CP025990.1|AUS77294.1|490519_491323_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.3243e-50
CP025990.1|AUS81382.1|476420_477053_-|DUF385-domain-containing-protein	gnl|CDD|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	1.91817e-08
CP025990.1|AUS77284.1|479125_479899_-|ABC-transporter-permease	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	3.68811e-08
CP025990.1|AUS77286.1|480626_481190_-|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.78352e-15
CP025990.1|AUS77290.1|484958_485735_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	3.94831e-53
CP025990.1|AUS77293.1|489512_490523_+|dihydroorotate-dehydrogenase	gnl|CDD|240091	cd04740, DHOD_1B_like, Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires FMN as co-factor. DHOD divides into class 1 and class 2 based on their amino acid sequences and cellular location. Members of class 1 are cytosolic enzymes and multimers while class 2 enzymes are membrane associated and monomeric. The class 1 enzymes can be further divided into subtypes 1A and 1B which are homodimers and heterotetrameric proteins, respectively.	2.63533e-117
CP025990.1|AUS77291.1|485718_486759_-|myristoyl-transferase	gnl|CDD|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	3.37168e-42
CP025990.1|AUS77285.1|479895_480630_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.74311e-67
CP025990.1|AUS81383.1|487636_488377_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	7.33468e-118
CP025990.1|AUS77292.1|486800_487640_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	3.86853e-58
CP025990.1|AUS81384.1|488823_489516_+|phosphorylase	gnl|CDD|350167	cd17767, UP_EcUdp-like, uridine phosphorylases similar to Escherichia coli Udp and related phosphorylases. Uridine phosphorylase (UP) is specific for pyrimidines, and is involved in pyrimidine salvage and in the maintenance of uridine homeostasis. In addition to E. coli Udp, this subfamily includes Shewanella oneidensis MR-1 UP and Plasmodium falciparum purine nucleoside phosphorylase (PfPNP). PfPNP is an outlier in terms of genetic distance from the other families of PNPs. PfPNP is catalytically active for inosine and guanosine, and in addition, has a weak UP activity. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	3.32582e-77
CP025990.1|AUS77289.1|483484_484801_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.36176e-120
CP025990.1|AUS77280.1|472979_473768_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	2.34525e-15
CP025990.1|AUS77281.1|474013_475300_-|oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.33026e-46
CP025990.1|AUS77283.1|477632_478130_-|NUDIX-domain-containing-protein	gnl|CDD|240041	cd04685, Nudix_Hydrolase_26, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	2.11545e-29
CP025990.1|AUS77282.1|475179_476013_-|trehalose-utilization-protein-ThuA	gnl|CDD|153236	cd03142, GATase1_ThuA, Type 1 glutamine amidotransferase (GATase1)-like domain found in Sinorhizobium meliloti Rm1021 ThuA (SmThuA). Type 1 glutamine amidotransferase (GATase1)-like domain found in Sinorhizobium meliloti Rm1021 ThuA (SmThuA). This group includes proteins similar to SmThuA which plays a role in a major pathway for trehalose catabolism. SmThuA is induced by trehalose but not by related structurally similar disaccharides like sucrose or maltose. Proteins in this group lack the catalytic triad of typical GATase1 domains: a His replaces the reactive Cys found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. S. meliloti Rm1021 thuA mutants are impaired in competitive colonization of Medicago sativa roots but are more competitive than the wild-type Rml021 in infecting alfalfa roots and forming nitrogen-fixing nodules.	4.89631e-119

Protein sequences

>CP025990.1|AUS77287.1|481247_481568_-|hypothetical-protein
MDTLPERQGIEGNDQEKGWLEGLTDYLVALAGTARWLGCGLEEVRRLLASAATAVARLVGVVGATCPRAPGCEPALRSGGMVHAATHTVAVIRSFVPAATALAAPR
>CP025990.1|AUS77286.1|480626_481190_-|TetR-family-transcriptional-regulator
MSVATVSKRERTLALLTERALALFEEQGFDQTSVVQIAASAGVSEMTFFRHFGSKEQAVLVDPFDPVIARAIGQRPLGEAALLRAVRGVRGALSGLDDAELGMVRRRVRIIASTLTLRVALAKQNEETAAAIQQQLISDGTDPRAARAAAAALLGALSAGLFEWAENEGTTLVEAIETALSVLEVGA
>CP025990.1|AUS77285.1|479895_480630_-|ABC-transporter-ATP-binding-protein
MTALLEVTGAVRSYSPGVGVRGVTLTVEEGEVHALVGLNGAGKTTLMRLILGIARLRSGDIRIAGTPVARMTGSRWRCVGHMLDRPFAYPELTAQRNMLVAARLRGLPASTAAEAARKALDDAGLGDYAAVRAGRLSQGNRQRLGVAVAMLDEPRLLVLDEPTNALDPAGVIDLRERLRRRAARGAGVLVSSHHLDEVARIAHRITVMNRGEIAGTLDPGGTDLERALFDLVLSDDERRNRERV
>CP025990.1|AUS77284.1|479125_479899_-|ABC-transporter-permease
MNNFRGACWVEIHKASAARPLWITGGVFVVGLALLGCGLVLAVSTGNDQVVDRLGAAADLDGWPLLFTIVTQIAAAGGLLAFGIALSWSFGREFTDGTVLGLLASPTTRSVVVLAKLLTHLLWVCAVALVSVGALFLVGILLGLGPVNGDVLADFTRLVLLLVLTGAVVVPTSLVATLGRGALPGIGAAIALIVVSQVAAIVQPATAAWLPFATPAIWALFPEVVGMAQLGLVIATSAVFCGLTVHVWNRLELDRGV
>CP025990.1|AUS77283.1|477632_478130_-|NUDIX-domain-containing-protein
MTASTSTVTPRIGARVLLLDPADRVLLIHALDPAEPDHHWWELPGGGLDDGEDLRDAARREAAEETGIMLPTLGRELWVRESRFRYKGRDHHRIEHVFLGRTQGNAPQVAPRPTENEKAGLIGRRWWPADELRQCRDKLLPAELPTLLDDLLSGRFSTAPLTLID
>CP025990.1|AUS81382.1|476420_477053_-|DUF385-domain-containing-protein
MIVLGGVLRVRTEDDGELVVHPGEVVHLPANSTNEFVAEEEVTACYVAGPPDVYARHADDPASHRWEPQPASRGTGTPDEAAVRRALDSDVLVDITTTGRRSGLPRRLEIWLYRSGGRFFLTGYPEDRPRDWYRNLLADPRLTVHLKESVVVDLPATAVEVTDAVDRRRVLDDILDQLSRPDNPQGLSEELDRAGWQARSPLLEITGLTG
>CP025990.1|AUS77282.1|475179_476013_-|trehalose-utilization-protein-ThuA
MSAVPDHRPAADTPGDAPGPPRITVWNENVHERTQPEVAERYPRGIHGAVAAAIADHLGPAASIRTATLDEPGQGLPPEVLDTTDVLVWWGHLAHDRVDDALVERVRERVLGGMGLVVLHSGHFSKVFTRLLGTTCALRWRNGDDRELVWTVDPRHPIAEGVPSPLVIDRQEMYGEFFDIPAPDELVFVSSFSGGEVFRSGVTFRRGHGRIFYFSPGDQDYPVYHHPDVRRVIANGVRWARPDRPVGSPPRLRRSPVGWWDDEPATHSGAASPGADR
>CP025990.1|AUS77281.1|474013_475300_-|oxidoreductase
MGEAGPAGRVPAEVAPLPGGLVGRRAGDTLGGRVPGCGPMTVGAFRTVDHHGPLRAVVVGAGAMGRAWLNTVDASPTVDLVGVVDLDPNAATAALSACGVPPVPVSTSLSALAEATLPDLVVDVTIPSAHYSVTREALDLGLAVLGEKPLAATLAEAIGLVVAAERAGRLFAVSQNRRHSPGLAALRRQVWTLGAVGTVSTEFFRAPRFGGFREEMEHPLLLDMAIHPFDAARYLVGGDPVTVWCEEFNPHWSWYRGDAAATAIFEMTGGVRYLYTGSWCAPGLETSWNGRWRVSGRHGAAVWDGEGEPVVEHAVPVAGAAEAAAESRARGWGSPSPTDIAGSLADFEHALRTGLAPSTVAADNLLSLAMVHGAIASAGTGTRVVIADLLAEAHRDAVDGADEDLRPALRDWRPPTPGGNGGGSGAGT
>CP025990.1|AUS77280.1|472979_473768_-|sugar-phosphate-isomerase/epimerase
MSDPTSPILSTPPAVQLYTVREQLAADRVGVLAALAGFGYGAVEPFDVLTDAPGLRDDLDAAGLAVCAVHAPVLSEDVDALFDGARTVGADTVIVPVAPPERFGDRDAVTALAAELNAVASRAADAGLRLGYHNHEFEFTDVDGTPALVVLADALAPEVVLEVDTYWAAVAGQDVPALLRRLGDRVRYLHVKDGPVTRTDPMTAVGAGRMPVAEVLTANPAVEWRVVELDDCATDVLAAVGDSLDWLRDNGFAHPAGGGSDR
>CP025990.1|AUS77279.1|471864_472983_-|gfo/Idh/MocA-family-oxidoreductase
MTAPDPVAPLGVAVVGCGSISDQYLTNLTSFPEVSVLFCADLDVDRAAAQAARYGVPASGTFGQALEHPGVELVVNLTVPAAHVEVASAALEAGLHVWNEKPLTLDLEDGRALVAQAGRVGRRLGCAPDTVLGTGFQAARRLIDAGAIGTPLTALALVQEPGPDRWHPNPAFLFQRGAGPLFDLGPYYLTVLASLFGPAHRVGAVGRQALTTRRIVAGDRAGTEFRVEVPTHVSALVEYAGGPAATLLFSFDSPLRRHGFVEVTGTEATLALPDPNHFAGEVRIRDRGDEEWRVAAPPVPSAGRGLGVVDMVRSLRAGTPHRASGELGLHVLELMTAIERSAAAGEFDTVRGSFPMPEPLPPGWAPGTATGS
>CP025990.1|AUS77288.1|482600_483461_+|DNA-polymerase-subunit-beta
MPHTEPTALARRIDRFREAAHAEPRLDGVLLYGSWTLGEADAYSDVEAYLFVRDADVADFDGVEFAARLGPVAYSYENQFGVLTVVFDDLMRGEFHVTASGAGVEQVRGWRGMIHLPDTERAVVLDRDGRLTSAARTLAEFQPPEPVGTASHLVGELTNWTLMEAHLLARGETARAHAWAQFMVAPAQLKLCRLLRDSTRHWLTPSRAVEQDLPAADVERYRATTSAAEPASVLAAAVRSWRWTRELAAEAEARWSISVPTELHGRIAALLADLEAGAGWPGPAVG
>CP025990.1|AUS77289.1|483484_484801_-|HlyC/CorC-family-transporter
MDSVATNLALVLLFVFAGGYFAASEIALVSLRDSQVDRLAATRGNRGKRLARLRSDPNRFLSAVQIGVTFTGFFASGYGGATIAVRLEPYLADWGLPAGLAATLALVLVTLFVSYLSLVLGELAPKRLALQKSEGVALFTAGVLDRLATVFRPLIWLLSRSTNAVVRLMGIDPQAAEEKVGEEELRDMVRTNEQLTVEERRLLDDAFAVGDRVLSEVMIPRTEVEFLDADLPLPDAVRLMRGKPHSRYPVIRESPDDVVGFVHVRDLLAVVDGEDPQGRTLADIARPVAAFPGSKPVLAALSQMRRKGGHLAMVIDEYGGTDGIVTVEDLVEEVVGEIYDEYDPGAVPSRRSPEGSVEVDGLLHRTEVEEQTGLTLPDGPFDTLAGYVVALFNRLPREGDSVEALHHRFTVRALDGRRVSRILVTPLRRSRPAEEDED
>CP025990.1|AUS77290.1|484958_485735_-|ABC-transporter-permease
MSSTTERRDRALPLLVGAASLAGGVGLWWALAAFSGLPSYVLPSPGQLVTRAVSLWQAGGLSIHLQQTLAEVLQGVALGSVIGIALAVLFVRVGWIERLLMPIIVVIQVTPKISIAPLIVLWLGLGIGSKITLITLVTFYPVLINMVGKLRGMPSTMHDLADVLNIRRGRRALLIDLPYSLPALAAGLRVGVLQAVTAAVIGEFIGAQAGLGYLEKQAQDNDDIQVVMICLILLSAIGWALYTLVGLIERKLTERFGG
>CP025990.1|AUS77291.1|485718_486759_-|myristoyl-transferase
MSPSPRSLRGVAALGLAAALGGVAACSPADNAGTTTGGDEGTTSVTVQIDGAAVPYYAPLYEAVEQGYFADHGLDVEFTYANGADIVQNVAAGNVDFGFPNGDSVITAYGSGVRTNVVHTTYQKGIGALLFANDSGIETPADLEGRSVAVTDLGSPNYAQLQAMLDSADLTVDDIDLRTIGTGAIVQALQSGEVDAIVFSRLRYFALQNAGMDVGQILSDEYLPSFGNILVTSPDTVENTPEVVASFTAALDEALQYTIDHIDESTAMSIEKYAPTFEGQEDEISEVLRDVYAAELWQSADTEENGFGHGNLDRWQEAIDSQAEFELIDEAFDAADLVRDHRELDN
>CP025990.1|AUS77292.1|486800_487640_-|ABC-transporter-permease
MSTAEITTGAATPPPAPGGNRPGGGPFGKGTPLRRITVAAAYLAVVLLAWQLYVTLADVPSYLLPDPLSVGDALWRLASSGELWPHLGYTVRNIAVGLGAGIVIGSLLGWVIASFRTVRLILAPYVVILQAAPKIALAPLLVLWFGLGLGSQLALIVMLAFFPMMIAMMLGLGEVTDDQRALGRVLNLGPARFFRLVQLPTALPALFAGARIAVIDAMTGAFLAEYISAQQGLGFLMVQGRSTYDTPQLIAAVVLTVVVGLTGFALVSLVERRALPWRR
>CP025990.1|AUS81383.1|487636_488377_-|ABC-transporter-ATP-binding-protein
MLEIRGVSKEYVSVKGASVRALDDVNLDIGDGEIIAIIGPSGCGKSTLLRMVAGLDTDYEGTIEWTRAPRPGRDIGFVFQEPALLPWRTVARNVSLGIEVQKDRSDLPTDRVDQLLELVGLRDFAKSYPKELSGGMRQRVAIVRALAYDPRILLMDEPFGALDAITRDKLHDDILRIWAATRKTIVFVTHSVEEAAYLADRVVVMSPRPGRLRSVHQVPLDRNRDAATRQLPVFAEFAGMLRGELA
>CP025990.1|AUS81384.1|488823_489516_+|phosphorylase
MPGDPARVDRAAAVLDDFRVLGQNREFRVGVGRRGEVEVGVCSTGIGGPSTEIALVELARLGVRTVLRTGGMGALSARIAPGDLCVVTEAVREGGAASWYADPEVRALSSPEVRTALAATADRAGERAHGITVLSCDSYYVGEGRPVPGLEDRAARRFAQVEALGVDAMDMECETVLAVGAAVGLRVGGLLVAHASRATDSWLEDYEPAQLRMLRVAADAAARLSSEGQR
>CP025990.1|AUS77293.1|489512_490523_+|dihydroorotate-dehydrogenase
MTAVTTGPRPVGDPPAGEDARARFFAAAPAPEGGAAPDLRVRLGSLTLRNPVMPASGCFGPELAPLVPTSEIGATVTKTVFARRRGGNPTHRLTETPMGMINSVGIPSLGTDGFVREMLPRYRAMAAPVIVSVGGLAVGEYLTVMDELAGARFDGVEVNVSCPNLEHGGLDIGTDPDAVARVVSGVVARTDVPVLVKLTPMVSSIAEVARAAEEAGATALTVANSFPGMTLDPRTRRPVLGNRVGGVSGPAVKPLALRLTWATAEAVGVPVIGCGGISTVDDALDFLAVGATAVQVGTAHFARPFVMAEIARGLAARCAAADATRLTDYVRTLGET
>CP025990.1|AUS77294.1|490519_491323_+|IclR-family-transcriptional-regulator
MSVDKPMQVVVRALDVLTALSNARGGRTLQDLHEELDIPLGSMHRVLSTLTQQGFVSRSRVNKRYFIGPAARALSAQRSHGGSPLVVPPAALAQAGEESGETVFLTEMIGELPVCVALVEARHPLRLFVRIGQEMPLHAAAASRSILAHQPEDVVRTLLAGTSMTGFTADTPRTVAEVLDHLAVVRDRGYDVCDDELDRDVWAVSAPLLAADGSVTSSVTLAAAGSRMSDPLTRARATEIVLRAAREMSFDLGWSGEDVAHSTQRGT
>CP025990.1|AUS77295.1|491322_491808_+|hypothetical-protein
MNQQSSPTRPRVDPTEFAADVLAAGGGTPAQPTSLPAALRGGRWVARPALLRRAAALLAPVLPAGVDRIVGVGPAEQPLVVATALHTGLPFAVLDDTTGDPATAGDAGPSLLVGEVHRHETVVLVAAAPSPADHHAGEAMRSHGVRVPRTALLSEVLATAD

Crispr_ID: CP025990_10

• CRISPR_ID: CP025990_10
• CRISPR_location: 554773-555412
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers

Consensus repeat of CP025990_10

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGACGAC	CRT
GGAACAGCCCCGCGTGCGCGGGGACGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGACGAC	CRISPRCasFinder

spacers of CP025990_10

>10.1|554801|33|CP025990|CRT
ATCATCGGCCTGGCCTCCGCCGGCCCGGCTGCG
>10.2|554862|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
TGCCGGCCTTAATCACTTCTGACGTCGTAACGA
>10.3|554923|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
ACGGCCGTTCCCATCGACGAGGCGGTGCCCGTG
>10.4|554984|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
GTCCTAGCCGCACTGTGCCGGGCTGGCCGGCCG
>10.5|555045|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
GCGGAGGCGGCGCTCCGGGCCTATGACCTGGCTG
>10.6|555107|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
CGCCGCTACCGGCGGACGGACGAAGAACAGGTA
>10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
TTTGCCCTGGCCCGGCCTGCCGCCGACCAGCCAG
>10.8|555230|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
CCCAGCTCAATCGGTTCGTTCCGGCCCGCGTCC
>10.9|555291|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
CATTGGTTTCGGACCGGGCAGCCCGCGCAGATC
>10.10|555352|33|CP025990|CRT,PILER-CR,CRISPRCasFinder
CCCAGCGGATGGCGGACATCCGAATGGAAGGCC

CRISPR arrays and Neighbor proteins around CP025990_10

CRISPR arrays

The CRISPR arrays of CP025990_10

>merge|CP025990|10|554773-555412|CRT,PILER-CR,CRISPRCasFinder
GCGCACAACCCGGATGCGCGGGGAGGACATCATCGGCCTGGCCTCCGCCGGCCCGGCTGCGGGAACAGCCCCGCGTGCGCGGGGACGACTGCCGGCCTTAATCACTTCTGACGTCGTAACGAGGAACAGCCCCGCGTGCGCGGGGACGACACGGCCGTTCCCATCGACGAGGCGGTGCCCGTGGGAACAGCCCCGCGTGCGCGGGGACGACGTCCTAGCCGCACTGTGCCGGGCTGGCCGGCCGGGAACAGCCCCGCGTGCGCGGGGACGACGCGGAGGCGGCGCTCCGGGCCTATGACCTGGCTGGGAACAGCCCCGCGTGCGCGGGGACGACCGCCGCTACCGGCGGACGGACGAAGAACAGGTAGGAACAGCCCCGCGTGCGCGGGGACGACTTTGCCCTGGCCCGGCCTGCCGCCGACCAGCCAGGGAACAGCCCCGCGTGCGCGGGGACGACCCCAGCTCAATCGGTTCGTTCCGGCCCGCGTCCGGAACAGCCCCGCGTGCGCGGGGACGACCATTGGTTTCGGACCGGGCAGCCCGCGCAGATCGGAACAGCCCCGCGTGCGCGGGGACGACCCCAGCGGATGGCGGACATCCGAATGGAAGGCCGGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|10|9|554773-555412|CRT
GCGCACAACCCGGATGCGCGGGGAGGAC	ATCATCGGCCTGGCCTCCGCCGGCCCGGCTGCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	TGCCGGCCTTAATCACTTCTGACGTCGTAACGA
GGAACAGCCCCGCGTGCGCGGGGACGAC	ACGGCCGTTCCCATCGACGAGGCGGTGCCCGTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GTCCTAGCCGCACTGTGCCGGGCTGGCCGGCCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCGGAGGCGGCGCTCCGGGCCTATGACCTGGCTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CGCCGCTACCGGCGGACGGACGAAGAACAGGTA
GGAACAGCCCCGCGTGCGCGGGGACGAC	TTTGCCCTGGCCCGGCCTGCCGCCGACCAGCCAG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CCCAGCTCAATCGGTTCGTTCCGGCCCGCGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	CATTGGTTTCGGACCGGGCAGCCCGCGCAGATC
GGAACAGCCCCGCGTGCGCGGGGACGAC	CCCAGCGGATGGCGGACATCCGAATGGAAGGCC
GGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|10|9|554834-555412|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGACGAC	TGCCGGCCTTAATCACTTCTGACGTCGTAACGA
GGAACAGCCCCGCGTGCGCGGGGACGAC	ACGGCCGTTCCCATCGACGAGGCGGTGCCCGTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GTCCTAGCCGCACTGTGCCGGGCTGGCCGGCCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCGGAGGCGGCGCTCCGGGCCTATGACCTGGCTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CGCCGCTACCGGCGGACGGACGAAGAACAGGTA
GGAACAGCCCCGCGTGCGCGGGGACGAC	TTTGCCCTGGCCCGGCCTGCCGCCGACCAGCCAG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CCCAGCTCAATCGGTTCGTTCCGGCCCGCGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	CATTGGTTTCGGACCGGGCAGCCCGCGCAGATC
GGAACAGCCCCGCGTGCGCGGGGACGAC	CCCAGCGGATGGCGGACATCCGAATGGAAGGCC
GGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|10|9|554834-555412|CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGACGAC	TGCCGGCCTTAATCACTTCTGACGTCGTAACGA
GGAACAGCCCCGCGTGCGCGGGGACGAC	ACGGCCGTTCCCATCGACGAGGCGGTGCCCGTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GTCCTAGCCGCACTGTGCCGGGCTGGCCGGCCG
GGAACAGCCCCGCGTGCGCGGGGACGAC	GCGGAGGCGGCGCTCCGGGCCTATGACCTGGCTG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CGCCGCTACCGGCGGACGGACGAAGAACAGGTA
GGAACAGCCCCGCGTGCGCGGGGACGAC	TTTGCCCTGGCCCGGCCTGCCGCCGACCAGCCAG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CCCAGCTCAATCGGTTCGTTCCGGCCCGCGTCC
GGAACAGCCCCGCGTGCGCGGGGACGAC	CATTGGTTTCGGACCGGGCAGCCCGCGCAGATC
GGAACAGCCCCGCGTGCGCGGGGACGAC	CCCAGCGGATGGCGGACATCCGAATGGAAGGCC
GGAACAGCCCCGCGTGCGCGGGGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77336.1|560757_561648_-|citryl-CoA-lyase	unknown	unknown	gnl|CDD|235748
CP025990.1|AUS77335.1|559195_560557_-|hypothetical-protein	unknown	unknown	gnl|CDD|238623
CP025990.1|AUS77334.1|557983_559087_-|carboxylesterase	unknown	unknown	gnl|CDD|365903
CP025990.1|AUS77330.1|554369_554597_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77327.1|546956_547823_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77340.1|565350_566337_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|225722
CP025990.1|AUS77324.1|542200_543481_+|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224567
CP025990.1|AUS77325.1|543581_544502_+|oxidoreductase	unknown	unknown	gnl|CDD|379468
CP025990.1|AUS77326.1|545981_546263_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77337.1|561644_562868_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
CP025990.1|AUS77329.1|550716_551892_-|glycosyl-transferase	unknown	unknown	gnl|CDD|273616
CP025990.1|AUS81395.1|552542_553694_-|epoxide-hydrolase	unknown	unknown	gnl|CDD|377658
CP025990.1|AUS77333.1|557026_557728_+|KR-domain-containing-protein	unknown	unknown	gnl|CDD|223377
CP025990.1|AUS77331.1|555786_555990_-|hypothetical-protein	unknown	unknown	gnl|CDD|224759
CP025990.1|AUS77328.1|549156_550248_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|223786
CP025990.1|AUS77332.1|556245_556875_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS77338.1|563207_564713_-|tripartite-tricarboxylate-transporter-TctA	unknown	unknown	gnl|CDD|225870
CP025990.1|AUS81393.1|544645_545911_+|threonine--tRNA-ligase	unknown	unknown	gnl|CDD|237050
CP025990.1|AUS77339.1|564712_565354_-|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl|CDD|377815
CP025990.1|AUS81394.1|547819_549109_-|hypothetical-protein	unknown	unknown	gnl|CDD|226382

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77336.1|560757_561648_-|citryl-CoA-lyase	gnl|CDD|235748	PRK06224, PRK06224, citryl-CoA lyase.	9.36603e-112
CP025990.1|AUS77335.1|559195_560557_-|hypothetical-protein	gnl|CDD|238623	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are catalyzed by atrazine chlorohydrolase (AtzA), hydroxyatrazine ethylaminohydrolase (AtzB), and N-isopropylammelide N-isopropylaminohydrolase (AtzC). All three enzymes belong to the superfamily of metal dependent hydrolases. AtzA and AtzB, beside other related enzymes are represented in this CD.	7.55602e-71
CP025990.1|AUS77334.1|557983_559087_-|carboxylesterase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.59952e-45
CP025990.1|AUS77337.1|561644_562868_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	6.84398e-149
CP025990.1|AUS77340.1|565350_566337_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|225722	COG3181, COG3181, Uncharacterized protein conserved in bacteria [Function unknown].	2.22244e-83
CP025990.1|AUS77324.1|542200_543481_+|carbohydrate-ABC-transporter-substrate-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.32568e-51
CP025990.1|AUS77325.1|543581_544502_+|oxidoreductase	gnl|CDD|379468	pfam14100, PmoA, Methane oxygenase PmoA. This family is a putative methane oxygenase.	3.35494e-65
CP025990.1|AUS77329.1|550716_551892_-|glycosyl-transferase	gnl|CDD|273616	TIGR01426, Glycosyl_transferase, glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance].	4.08128e-122
CP025990.1|AUS81395.1|552542_553694_-|epoxide-hydrolase	gnl|CDD|377658	pfam06441, EHN, Epoxide hydrolase N-terminus. This family represents the N-terminal region of the eukaryotic epoxide hydrolase protein. Epoxide hydrolases (EC:3.3.2.3) comprise a group of functionally related enzymes that catalyze the addition of water to oxirane compounds (epoxides), thereby usually generating vicinal trans-diols. EHs have been found in all types of living organisms, including mammals, invertebrates, plants, fungi and bacteria. In animals, the major interest in EH is directed towards their detoxification capacity for epoxides since they are important safeguards against the cytotoxic and genotoxic potential of oxirane derivatives that are often reactive electrophiles because of the high tension of the three-membered ring system and the strong polarization of the C--O bonds. This is of significant relevance because epoxides are frequent intermediary metabolites which arise during the biotransformation of foreign compounds. This family is often found in conjunction with pfam00561.	9.89268e-64
CP025990.1|AUS77333.1|557026_557728_+|KR-domain-containing-protein	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	4.04141e-30
CP025990.1|AUS77331.1|555786_555990_-|hypothetical-protein	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	0.00215826
CP025990.1|AUS77328.1|549156_550248_-|AAA-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.10716e-12
CP025990.1|AUS77332.1|556245_556875_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.38557e-08
CP025990.1|AUS77338.1|563207_564713_-|tripartite-tricarboxylate-transporter-TctA	gnl|CDD|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
CP025990.1|AUS81393.1|544645_545911_+|threonine--tRNA-ligase	gnl|CDD|237050	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed.	8.08324e-175
CP025990.1|AUS77339.1|564712_565354_-|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl|CDD|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	5.02555e-08
CP025990.1|AUS81394.1|547819_549109_-|hypothetical-protein	gnl|CDD|226382	COG3864, COG3864, Uncharacterized protein conserved in bacteria [Function unknown].	3.16212e-20

Protein sequences

>CP025990.1|AUS77330.1|554369_554597_-|hypothetical-protein
MKLRAFDQLLAGLITTDHPEVTNVHCYGEDRPQHRTRFRVDFASGAAAYLYVDDVSGPGIPRMAADSPEVPREAL
>CP025990.1|AUS81395.1|552542_553694_-|epoxide-hydrolase
MITPFRIDVPHADLDDLTDRLARTRWPNEIADAGWDYGFPLTRLRDLVEYWRTGYDWRAHEAGLNELPHFTTEIDGQRIHFVHVRSSKPDALALILTHGWPGSFLEFLDVIGPLSRDFHLVIPSIPGYGFSGPTRERGWDIPRIARAWAELMRRLGYERYGAQGGDFGSGISTALGAVAPDRVVGVHVNYLPTPPVPDADVELSPADEVRLDRIRQLMANRPPYQALQALTPQTIGYALTDSPVGQLAWIAERFAHWTDPDSRISDDRMLTNVSLYWLTATAASAARLHREAPRRAERCPVPVGVAVFAHDITLPVRPLAERLYDIRHWSEFERGGHFAAVEVPELLAADVRTFFLSRLAEEPSGAASAAPTGQPRAGSPAQA
>CP025990.1|AUS77329.1|550716_551892_-|glycosyl-transferase
MSRRRAHIAMVSVPAVSHVLPSLEIIRELVARGHRVTYANDPAVSHLITPTGAELVPYRSVLPVADNDWPEDPIAAMGLFLDEGIQALPALRAFYDADPADVYLYDIGAYAARVIAETQGRPLVQLSPAFVSWDGYDEEVAAPLWGLPGADAYRERFGRWLADTGATTTDMDAFAGRPSTSLALIPRAMQPNADRVDTTTVTFVGSCAGPRADRDTWVRPEGAEKVLLVSLGSAYTRQPEFYRQCLAAYGNLPGWHVVLQIGKYVDPAELGAIPGNVEVRSWVPQLSILEQADAFVTHAGMGSSAEGLSAGVPMIAVPQAVDQFMNADRLVELGVARRVDTADATAEVLRDTLSELVADPEVARRSARSREDALLEGGTSRAADLIEAALG
>CP025990.1|AUS77328.1|549156_550248_-|AAA-family-ATPase
MTSNQTVREALAVAVAANLPVLLWGDPGTGKTSTVLALGERLGLPVEAVVGSIREPSDFAGLPVVRADGTWFAPPRWAERLATAGTGLLFLDELTTAPPAVQAAMLRVVLERTVGDLTLPTTVRIVAAANPPGLAADGWELTAPLANRLVHLTWEVSAADIAEGFTRGFAADDGSPPPTAPTPAQVAAAKARIGEFLRVRPELLLDVPDSPERAGRGWPSPRSWAMAATALAAGEANASDEPVIAALLVGAVGEGAGYEALTWLRTLDLPAPETLLANPDAPLPERADRRHALLSALVAHVLADGTVDSWERAWAVIGRVARSTTDVAATSARTLAAHRPTGATPPTTVLELAPILRAAGLLP
>CP025990.1|AUS81394.1|547819_549109_-|hypothetical-protein
MRRFAEARLWAAAQAPYLASAVFALRPVVLEARSDEHTGEPVPDPEFRALPTDTRWRVHLDPGTLLTTPVEEAGWWLLHHIGHLVRRHAARGPNRGAGRRTGGTGGADEEAAHRWNQAADAEVNDDLESAGLTTPEGVVSPRALGLPEGRLAEEYVSLIEVLDTAHRRGGRRLVDLVDCGPAVRGLDGRYEETGAGEGIDDTERHVLELALARDIERRAAARTAVPGGWRRWAEDRRRPVVDWRTRLGAVLRRGVRRTTGRVDFSYRRPSRRPGPGGVLLPTMVAPAPGIALVIDTSGSVAAPVLAGFLSEITGVLARAAGPERRLRAICCDDRAHPVQEVREAADIELTGGGGTDLRAGIAAALALRPRPDLVLVLTDGHTPWPERRPPVPVVVGLVAAHPPPADAPTPPAWAHPIPLPATAPRGAEA
>CP025990.1|AUS77327.1|546956_547823_-|hypothetical-protein
MSIAAADEPDDHGERRDGTREGAHEPAPSNEARRQAAPGHDGDPVPEDLHEWTGRGVTVAEARQWIDHGFLLDSAERWRTSGVYTAEQALAWRTAGLTPYTVRPLLRAGMTPRDAVRWHELGYGHAEAAERHLAGENPRPRRWWWRLMAPGPAGSSELDDGQHATLRMLLGAGVPAFTARAYLDTGWSGEEAVPWAGSGTSPTHAALYRVMGFTPAEAADLGERGEDPAALLARWWDAGVPRAEVPSWVVAGFTVEEARRARAAGTTAEQAAVLRALGGGQPPDQDAP
>CP025990.1|AUS77326.1|545981_546263_-|hypothetical-protein
MDDDYRLDVPASFDDSDDEDGQVHPIARRLFSGATAAEVFEKARRWVSEHDVFLIDVSWNWSHDEPEPFWLSVYFRFEFDEDEDEDEGTSAGA
>CP025990.1|AUS81393.1|544645_545911_+|threonine--tRNA-ligase
MRSLASRKRGDLMHDHRRLGRELELFDTDPLIGAGLPYWRPAGAAIRHTLEEYVRAVEREAGYQHVYSPVLGKRELYEMSGHWAHYADSMFPPMDLGGEQVVLRPSLCPHHAVIYRSRSHSHRELPVRIAEVGGMFRSELSGVLGGLTRVRGIQLNDAHVFCAPDQVAAEVRGALELIGRAYRDLGLRAARYRLSLPPEGAAVVGDPEDWRRASTLLAGVLEELGVPHDAEEGEAAFYGPKIDVQVVDGAEREATLSTVQVDFHQPSRFDLRYVGADGRRHRPVMVHRSIIGSVERAVACLVEQHGGAFPAWLAPVQVAVLPVSDQEVGAAAGLVERCAGRGLRAELVGPDRGSLGARVRRSRLVPYQAVIGPREAAEDRVALRLRDGRRLDPLASGEAVDRVAAVVDARSGVLWPDPVAA
>CP025990.1|AUS77325.1|543581_544502_+|oxidoreductase
MTAAEPDPTPEATLRVAGTPVADHVTDVGWWEPTLAPRPHLHPVRTLAGVEVTEARPVDHPWHLGVFVAVQDVEDCNFWGGRTFVRGQGPTWRPDHGSVRHERWTHRDADALASEQSWISVAGETVISETRATRSLVGPPTTGGWVLDYAFTLRNVTGRDLDLGSPATNGKVGGGYGGFFWRAPLSSATPRVFTATAEGEEAVHTTRSGWLAFLGHHPNAEDLVREDGPTGDYTLLFVPADERTAEDPWFVRVADYPGVGSSLAPEHPLRLPAGDSLRRRFRVLVLDGHLERGACADAARSVAELP
>CP025990.1|AUS77324.1|542200_543481_+|carbohydrate-ABC-transporter-substrate-binding-protein
MPAHRPRRVAWVALGSAVALTAAGCGGSAADDGSVTLLFTWWGDDSRARATQEVVDLFEERNPGITVNTSFTSGGNYFEKLSTEVAGGNPPDVFQLDYSNLREFADRGVVLDLADHGDDVDLDGVAEAMRDAGSIDDGVYGLPMGQNTHALIYDPRLWEEAGVPTPEYGWTWDDFFDSARAITESTDGEVYGSTDFGWSWETFQAWLRQRDRDLYAEDGSLAFDESDVREYLTLLDDFRAGQATTPASLNGMIDGAVENTPFAKGRSATDLAWDSVLAGYDTAMGRPLAMAPLPSDTDRFGQYAKPSMLISAARASDHPREAAMLIDFVINDVDAGRILGTTRGLPPNQEVREALADDLEGLDRQVYDYETGLEEHLEGTPPAPPEGNGTLKREWQRHNDAVSFGNKTIEEAAADFMRIAEQEVGA
>CP025990.1|AUS77331.1|555786_555990_-|hypothetical-protein
MAEATGVGLADLSEKTADLVAVGYVVWSGEPGNRVLRMTPAGRMVALDLLPAVEAFLAELAGASSAP
>CP025990.1|AUS77332.1|556245_556875_-|TetR/AcrR-family-transcriptional-regulator
MRADAQRNAEKLRAAAAELFQERGLQVPLKEIARRAGVSHGTLYNLFGTREALIDAVVAEGAARRLDEVAQQALSHDDAWQGFAHYVERLCELQATDPAVADVVGGRYPDAERLMAACGRSMEAARRIVRRAHEAGALRPDFTNADLVFAFAANALLARATAAAAPDAWRRQVAYLLDGLRAEAARTPLPASQPTEGQVREALRGLGEV
>CP025990.1|AUS77333.1|557026_557728_+|KR-domain-containing-protein
MSKVIAVFGAGTGLGSSVARRFGREGFRVALVARRRPRLDALVEQLAAEGIEAAGFTADLSRPAEVPALIASIRDRFGRIDVIEYGPFSADQGFGPAAQTDAALLEQGLPMFLLTPVEVVRAVLPEWTERGDGAFLLTSGVTAVHPVPGLSGLAPVGAAIRNYLYSLHGELAEAGIYVGTLAVGATIARSEMSALVADSGASTGFPVVDPDDLAEQYWDMYTTRHQVERIHPA
>CP025990.1|AUS77334.1|557983_559087_-|carboxylesterase
MTVPHGGHTTPAFAAVRDAFLDLLHTGRETGAAVAVLHRGRPVVEIWGGWRDQHRTHPWTADTLVHTYSVGKPLAALATLTAVADGALDLDDPVADVWPEYGQAGKERTTLRHLLAHQGGLPAFPETAAHLPLLADDQLRAALARAEPEFAPGTAHAEHALTYGHLLDGVLRGTGAASLGQVFRDRIARPLGLDAHFGVPAQDLPRVADLEYGDARWPTATAGEPGSLEHRAMTRPTGALDVEVLNGPAWRRAEFPAIGLHTTASAIGKFYAGLVDPGGPVAGLLGERVHRELLSPQARGTDLFLGHEVTWSLGFQLSGDEVAMGGAGGSAAWVSQGEEYACAYVTRRLAGFDRVDTIEHAVRECLS
>CP025990.1|AUS77335.1|559195_560557_-|hypothetical-protein
MVDRIYHGALVVTGPRDAHPFVGDVGIDGDTIAFVRPTTGAVVGGGSAPDTWPPASHPAAEHVDATGHVLLPGLVNGHLHPTPALLRTALAATTIDHQDGHPLADGLYAALTADRETLRLSAKLAITEAISSGTTALCLHEYLDPVVAAEVAADLGIPATVALHPEPGGTAWRDTLRQVQDTGCSAMLAGVNENDPDHTPEYLRELVTHAGDLGIRVHTHVSETTLRHETTRARTGRSPIRYYQALGLLDHLYAVHCTAVEPADIDLLADHRVPVVLTPSSEALLGDGTPPLPALLAAGARLALGTDGSAWAGSEDLLAELRATALLTRARWGPEAVDGAQLIELATLGGADVLDTPDTRGAIEPGRRADLVLLDARRPGLRPLATTDGPLSTARDVLAFAATGADVVETTIGGRVRYRRDGPGLLAGDELAELDERARRVWRDSGAATATSW
>CP025990.1|AUS77336.1|560757_561648_-|citryl-CoA-lyase
MTQHDENTRPADTASATGEAATIPTEKVTGWWATDIARIHPGEIALRGYPVEQLIGRAGFADTIWLMLRGDLPTPGQGRLLEAALVSAVDHGPQAPSIAAARMAATCGVGLNNAVATGVNLLGDVHGGAGQQCMDLLARLHTEVAAGETLDAVAARAVTEHREAGRHVPGFGHRFHPRDPRRDPLLGLLTEAADAGVVPGDHLAIGLALEDALATGRRRPVPMNIDGATALIYSELGFAPELGRGLFVLSRSVGILAHAWEERRSGTRIKGPIPRPLLADYTGPDLRDVPTTPPQH
>CP025990.1|AUS77337.1|561644_562868_-|CoA-transferase
MPTAATDGEGLLSGVRVLDLSNVLAGPYASYQLGLFGADVIKVEVPGSGDLARQLGADPDLNRDLLGASFLAQNGGKRSVTVNLKSEAGREVFTRLVAQADVLVENFRPGVLARLGFPWERLQEINPRLVYCAISGFGQSGPLRDRPAYDQIIQGLSGMMAVTGTEDTAPLRAGYPVGDTLGGLAAAMAVAAALVRVARTGVGSCLDVSMLESAITALGWAASNHLIAGRDPVPMGNENATAAPSGTFRTGHGALNIAANKQEQFEAVCRVVGRPDLATDPRFARREDRKTHRLALRDALEAALASHPAEHWENALAEAGVPAARVLDVRQALELDQIAERGFLHDLPHPADPDRTVRVLGNGVRVDGHASTPSAPPPVLGEHTTPLLRELGYTDEEIRALREEGAV
>CP025990.1|AUS77338.1|563207_564713_-|tripartite-tricarboxylate-transporter-TctA
MEALNNLFEGFAGAVSPINLLWVVVGAVLGTAVGVLPGLGSAMAVALLLPVTFSLDPIGAFIMFAGVYYGGLFGDSTTGILLNTPGNSSAIATTFEGHRMAKAGRAPQALATSAIGAFTGGMIATTLVVFFAPHLAELASLFGPAEYFALAVFAFVATATVVAESVIKGLAALVIGLALAMVGIDGPSGASRFTLGMPQLFDGVAIVVITVGLLALGEVLFVASRIHRDKGRTTTPFTGRPWLSRSDVRKAWPAWLRGAGFGVPFGVIPVGGSEIPTFMAYGTERRLDRRRKNPMFGKGAIQGVAAPEAAGNATAGSAMGALLALGLPTSATAAIMLAAFQQYGMQPGPLLFERNAELVWTLLASLFIGMVVLLILNLPFAPLWAKLLMIPKHYLYAGISVFCGLGVYATSSSTADLVLLLLIGLLGFMMRRYGLPLAPVLIAVILGPLAETELRRALAVSEGDVGILFDSGIAVTLYVILALAVLFMVVNKIRRRVRQDI
>CP025990.1|AUS77339.1|564712_565354_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MSSTVESSSGAGTEHRSFWTGRSGLVVAAFLLGLAIFLTYGTLTMEVPPNVSSPGPQFFPTIVTVLTYLLAVLLAVQVIRHPSVPQEETAAEETDGAAEEEGAGEGAEASGEETPASAGGAGERPAVERYRTHTDWRTVGIVVASFVAFTVLLVPVGWLISGALLFWGVTYALHGKRPLFDASVALVVSSVIQLAFSAGLGLNLPAGILGGVF
>CP025990.1|AUS77340.1|565350_566337_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MRPKRPLVTGIYGVVVAALVVLAGIDAGNSAAGASARNKLTLMAPAAPGGGWDLAARESQQALRSSGVVNNAQVVNVPGAGGTIGLSQTVGRAGDETTLMVTGTVMLGAVEVNGSEHGLDDVTPIARLADDYVVVVVPADSPYQTLDDFLADWRSNPHGTAIGGGSLGGTDHLLAGLLAQEGGVDPGSLNYISYAGGGEVMTALLSHTVAVGVSGYNDFSDQIEAGRLRALGVSAAEPVEGIEIPTFIEQGVDVELPNWRGVMAPPGLTDEARAEMEAIITEMVETEEWADALDRNRWADTFMVGEEFEEFLDQDIARIRQVIEELGL

Crispr_ID: CP025990_11

• CRISPR_ID: CP025990_11
• CRISPR_location: 711658-712113
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: WYL,csa3

Consensus repeat of CP025990_11

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT

spacers of CP025990_11

>11.1|711686|34|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGGGTCGGCATCCGGCCGGCTGACCGTCACGTCG
>11.2|711748|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGCCCCGGACGGCATCCGGGGGATGCCCGGCCC
>11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCATGCTCGCCTCGGGCGGCACTGGCCCGACGG
>11.4|711870|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGCTGCCCTGAGCCGGTTGGCGATCTGCACAGA
>11.5|711931|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCCGTCGGATTCCGGCCTGGGCGAGCGGCCTTA
>11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
AACGCCCGGCTGTAGGCGGTTCGGGCCTGGCCC
>11.7|712053|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCGCCGACCGGGTGCGAACCGGGTTGGACCTCG

CRISPR arrays and Neighbor proteins around CP025990_11

CRISPR arrays

The CRISPR arrays of CP025990_11

>merge|CP025990|11|711658-712113|PILER-CR,CRISPRCasFinder,CRT
GGAACAGCCCCGCGTGCGCGGGGAGGACGGGGTCGGCATCCGGCCGGCTGACCGTCACGTCGGGAACAGCCCCGCGTGCGCGAGGAGGACCGCCCCGGACGGCATCCGGGGGATGCCCGGCCCGGAACGGCCCCGCGTGCGCGGGGAGGACCCATGCTCGCCTCGGGCGGCACTGGCCCGACGGGGAACAGCCCCGCGTGCGCGGGGAGGACCGCTGCCCTGAGCCGGTTGGCGATCTGCACAGAGGAACAGCCCCGCGTGCGCGGGGAGGACCCCGTCGGATTCCGGCCTGGGCGAGCGGCCTTAGGAACAGCCCCGCGTGCGCGGGGAGGACAACGCCCGGCTGTAGGCGGTTCGGGCCTGGCCCGGAACAGCCCCGCGTGCGCGGGGAGGACCCGCCGACCGGGTGCGAACCGGGTTGGACCTCGGGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|11|10|711658-712113|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GGGGTCGGCATCCGGCCGGCTGACCGTCACGTCG
GGAACAGCCCCGCGTGCGCGAGGAGGAC	CGCCCCGGACGGCATCCGGGGGATGCCCGGCCC
GGAACGGCCCCGCGTGCGCGGGGAGGAC	CCATGCTCGCCTCGGGCGGCACTGGCCCGACGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGCTGCCCTGAGCCGGTTGGCGATCTGCACAGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCCGTCGGATTCCGGCCTGGGCGAGCGGCCTTA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	AACGCCCGGCTGTAGGCGGTTCGGGCCTGGCCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGCCGACCGGGTGCGAACCGGGTTGGACCTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|11|10|711658-712113|CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GGGGTCGGCATCCGGCCGGCTGACCGTCACGTCG
GGAACAGCCCCGCGTGCGCGAGGAGGAC	CGCCCCGGACGGCATCCGGGGGATGCCCGGCCC
GGAACGGCCCCGCGTGCGCGGGGAGGAC	CCATGCTCGCCTCGGGCGGCACTGGCCCGACGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGCTGCCCTGAGCCGGTTGGCGATCTGCACAGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCCGTCGGATTCCGGCCTGGGCGAGCGGCCTTA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	AACGCCCGGCTGTAGGCGGTTCGGGCCTGGCCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGCCGACCGGGTGCGAACCGGGTTGGACCTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|11|10|711658-712113|CRT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GGGGTCGGCATCCGGCCGGCTGACCGTCACGTCG
GGAACAGCCCCGCGTGCGCGAGGAGGAC	CGCCCCGGACGGCATCCGGGGGATGCCCGGCCC
GGAACGGCCCCGCGTGCGCGGGGAGGAC	CCATGCTCGCCTCGGGCGGCACTGGCCCGACGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGCTGCCCTGAGCCGGTTGGCGATCTGCACAGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCCGTCGGATTCCGGCCTGGGCGAGCGGCCTTA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	AACGCCCGGCTGTAGGCGGTTCGGGCCTGGCCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGCCGACCGGGTGCGAACCGGGTTGGACCTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77426.1|696824_697040_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77437.1|714162_715152_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
CP025990.1|AUS77432.1|704556_706800_-|daunorubicin-resistance-protein-DrrC	unknown	unknown	gnl|CDD|223256
CP025990.1|AUS77427.1|697747_698566_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS77440.1|719760_721710_+|DNA-helicase-UvrD	unknown	unknown	gnl|CDD|223288
CP025990.1|AUS77441.1|721826_724409_+|hypothetical-protein	unknown	unknown	gnl|CDD|379207
CP025990.1|AUS77428.1|698587_698779_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS77439.1|716773_717568_-|aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|270701
CP025990.1|AUS77435.1|710497_711469_-|EamA-family-transporter	unknown	unknown	gnl|CDD|183142
CP025990.1|AUS77431.1|703152_704226_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	unknown	unknown	gnl|CDD|225316
CP025990.1|AUS77429.1|699310_700054_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
CP025990.1|AUS77430.1|700486_702067_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
CP025990.1|AUS81409.1|713372_714170_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP025990.1|AUS77438.1|715242_715959_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
CP025990.1|AUS77444.1|726889_728992_+|hypothetical-protein	unknown	unknown	gnl|CDD|379155
CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
CP025990.1|AUS77434.1|708078_709971_-|hypothetical-protein	unknown	unknown	gnl|CDD|223496
CP025990.1|AUS77442.1|724589_724931_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77443.1|725184_725580_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.8e-15	51.5	0.0
CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	2.6e-53	176.2	0.6

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77437.1|714162_715152_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.3076e-62
CP025990.1|AUS77432.1|704556_706800_-|daunorubicin-resistance-protein-DrrC	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
CP025990.1|AUS77427.1|697747_698566_+|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.48013e-08
CP025990.1|AUS77440.1|719760_721710_+|DNA-helicase-UvrD	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.56819e-09
CP025990.1|AUS77441.1|721826_724409_+|hypothetical-protein	gnl|CDD|379207	pfam13472, Lipase_GDSL_2, GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.	8.57046e-14
CP025990.1|AUS77428.1|698587_698779_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	8.04639e-20
CP025990.1|AUS77439.1|716773_717568_-|aminoglycoside-phosphotransferase	gnl|CDD|270701	cd05152, MPH2', Macrolide 2'-Phosphotransferase. MPH2' catalyzes the transfer of the gamma-phosphoryl group from ATP to the 2'-hydroxyl of macrolide antibiotics such as erythromycin, clarithromycin, and azithromycin, among others. Macrolides penetrate the bacterial cell and bind to ribosomes, where it interrupts protein elongation, leading ultimately to the demise of the bacterium. Phosphorylation of macrolides leads to their inactivation. Based on substrate specificity and amino acid sequence, MPH2' is divided into types I and II, encoded by mphA and mphB genes, respectively. MPH2'I inactivates 14-membered ring macrolides while MPH2'II inactivates both 14- and 16-membered ring macrolides. Enzymatic inactivation of macrolides has been reported as a mechanism for bacterial resistance in clinical samples. MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.11772e-25
CP025990.1|AUS77435.1|710497_711469_-|EamA-family-transporter	gnl|CDD|183142	PRK11453, PRK11453, O-acetylserine/cysteine exporter.	2.78688e-60
CP025990.1|AUS77431.1|703152_704226_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	gnl|CDD|225316	COG2518, Pcm, Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones].	3.24705e-28
CP025990.1|AUS77429.1|699310_700054_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	5.88538e-41
CP025990.1|AUS77430.1|700486_702067_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	8.08226e-62
CP025990.1|AUS81409.1|713372_714170_-|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.44904e-08
CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.10456e-45
CP025990.1|AUS77438.1|715242_715959_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.09316e-09
CP025990.1|AUS77444.1|726889_728992_+|hypothetical-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	4.56082e-25
CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	8.85964e-15
CP025990.1|AUS77434.1|708078_709971_-|hypothetical-protein	gnl|CDD|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	4.56469e-05

Protein sequences

>CP025990.1|AUS77435.1|710497_711469_-|EamA-family-transporter
MPLRHCLLALSVAVVWGLNFVAISASLEHFPPMFLVALRFAVVAIPTVLFVPAPGVPLRWLLGYGCGFGIVQFLFLFWGMAVGMPTGLASLVLQSSAPFTVLLGATVLRERISARQLAGILVGVGGLAVVGWYRAETASVVPFLLTVAGAFGWAVGNICGRLAKPSSPVRLMLWMCVVPPLPMFALAFVVEGPTRIGVSLSTLGAPGAWAALLGLAYTVLIAGVLGSGAWTWLLARHPAGVVAPFSMLAPVVGMTAAWLVLRETVAAWELLGGLLIVGGVLLGCVGRQGTGTRLPRVAPPGAPEPSEARVAGNGRPVNPRPPG
>CP025990.1|AUS77434.1|708078_709971_-|hypothetical-protein
MAVVGPIDRGKTSMIECVDFLFGRTVQFRGAVDQRLRAVQAQIQIGDGTYRVTRDRDHPGTVWVEEADGTPVGHFLLRSQDEKPSWSTWLLMRLGLDEMFASVRLPGDRRLSFAEDLLPYLHIRQEDIDRFVVRPPSRTTPRLAVFKLLLHLTTPETERLAGAITDTRNRITLQRRKARDLARFLRSSDATSEKALDAELVTLREREREARDVVARLRAAANASATHMAHLHRQVDEARARLSEAEDTVERDHRRHQEARSKVKALRDSLSHVDAVEDVEPCEREQLTYAFDACPACRQGLGERVVPPGHCGVCVLPLPGAAVEAERARLRKMEEAAATALATADQDLRGSGEVVRRARADLDTARQRVDQHLAASTSPHVDAIAAATGELAALSAQISALTRLRAPHDQLRRLERDTERDARKLKEMRERHLQLSAQLVRPGDALERLNSLFRQIVHAFDLPWATGRARLDPETWTPLVDDQDFGQRGGGSRTAVSVAYSLALLLYALEQPADFHLPHLLILDSPQKNLGRNSHDQALAARMYRWMADYLQDRAAALSGTTSGQRYRDFQLVIVDNAIPAEVRDSFRPTVTFDEDTGFVRELEHPHGPPLPAEQLRFGDDVGIELGSTA
>CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator
MADVTQRSLALLAALQTGRAFTGGELARHLDVSPRTLRRDIDRLRGYGYPVETQPGPGGYYRLATGNSMPPLLLDDDEAAATLLALAALAATGSAEQGSLDAAATSAYGKVDQYLPARLRPRVAALRASLETDQTAAPSTSTETLSTLGTAIQRSHVVAFDYTTARGTTSSRRVEPHRQVHLLHRWYLLAWDLGPEDWRVFRVDRISDARDAGRSFRPRPLPAGGGVEHVRQAVTRARQRVVVTIEAPIAKVADALRHQYTELTPLDADRTRIVLMPESWQWLVLNIALVDADFTIEEPASMREQCQRFGARLAGGGQG
>CP025990.1|AUS77432.1|704556_706800_-|daunorubicin-resistance-protein-DrrC
MSQQRNIRVRGARTNNLKSLDVDVPRGQLVVFVGLSGSGKSSLVFDTIAAEAGHQLNETFPPFVRNRMTKWTRPEVTEISGLSPAVVIGQRRVGGNSRSTVGTYTDAWSYLRLIFSRLSTPHVGESNRFSFNDPTGMCPTCSGLGEVVVTAVDRVVDMDRSLEDGAVRLPGFVQGGYWYSLYADIGSFDATTPLRDWSEDQRQALLYGGEHAERLDPRPPKGFEGVVERFERIYLNTSEDLSERKRETLAQFTRSDLCPDCHGDRLNEESRSATVLGRTIGAMARMEVSDLADLVTGVTEPSVRPAVAALKDRLDALVTIGLGYLHLGRPTPTLSGGESQRIKTVKHLGSSLMEMLYVFDEPTVGLHPHDVSAMITLLRQLCDKGNSVLVVEHDPAVMAAADQVVEIGPRAGEHGGALVFQGPFSELGAAGTATSVELSRTRRPREEPRTPTGQVVVADACRNNLRKVTVEIPTGVMTVLTGVAGSGKSSLARELVNQHDAIVIDQRPVSASRRSTPITYTGVAAPIRKLFARRNGVAASLFSANSEGGCPDCGGTGVIYTDLAFMDGQETVCETCQGRRFTPDVLRYTVDGLSIADVEDLTIEEAIRRLPDRAITKALSHLDKVGLGYLRLGQPLSTLSGGECQRVKVAKELREASMPTLYVLDEPTTGLHLADIDTLLGLLDDLVEHGHGVVVIEHNLDVIRHADWLIDLGPGPGRHGGRVLYEGPVTGVGDTPTGRALREAFPS
>CP025990.1|AUS77431.1|703152_704226_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase
MVHSWSLFLLGGVVVTIAPTVASVAGTIPETHYSHHGGRGHTPMRSNPLVIHRELTLLDVHPAQRVCEIGTGSGYSGALLSSLVGEDGRVVSVVSVDIDPYLVQWARCAHRERGVRNVRCVVGDGRQGFAAEAPYDRLVAWCTPPHLPKAWVDQSQVGGVIVTPLPVARVPQITVVAEILVDEDRIPRVQRVLHGGYMETVSSPCDPDTPTRLVDWEYRLPSAAWRSVGWRKEDNELRDGARGALDRLLARSSIRETVGEEDIDWGSWRTWAAATDDHYLTAVGWPSGGIAVGHSTPESVAVLRHDGTILADRRASPSLRIVRDWFRAWDRAGRPAVEEYEGTLHPQQEGWRLRLSR
>CP025990.1|AUS77430.1|700486_702067_-|MFS-transporter
MLMVKHSSTEEIGTAPPRPPRPGVVLTVVSLGAAIVALDGTVISVANPDIAADLRPSLAGLQWVTNGYLLAIASTLVIFGRAADRFSRRTFWLTGTALFTVASLMIALSGSINALIFWRVVQGIAGALVMPAGVGLLRATFSGPALSRALATWSGCTAIAAAAGPVVAGLLVQAQGWQSVFLINVPIGAVAVTLGALHLRDQRGTTETGRLDAVGAVLLALTMVSLAWGVLQAEHGHLDATVLGYLGLAVVLGALFVWRQRRAARPLLDLTIFANRTVPAATLLVVFAFFTLYGTLFFLTLYMQRVQGVSALEAGVRVLPLTAALALASALVGHLNARVGPRPALLGGMTIIAASAFGLSQLEVGSTYHAMWPSLLGMGLGIGMVSVASTDALVSNVHPRLSSVAGGLQQTASQLGGVMGTAVLTTLLSVAVSTGLAGNLAERGVGPDESQFVLDRADRVTQGEVPLPPGVGPGTADAIVEAGHASFVAGMTGAMSVAVVVALVGVVAALFVRKGEHSSADAVVMH
>CP025990.1|AUS77429.1|699310_700054_+|GntR-family-transcriptional-regulator
MQTRPWIQIAEDLRLRITSGEYAEGERLPSGSTLMGEYGVARQTIQNAVDQLRAEGLVSSIAGRGWFVSKRRPITRLARNRLSADERTAGRGAFLTDAAAADFTPTVTVRVWKEEAGEEVASYLDVPSGTQVLVRDRVMRADGDVVQLAASYLPADLVQGTQVEHVDTGPGGTYARLEEAGFALSHFTEFVSARSPRPAEAESLRIPHGHPVIQVTRVAFAADRPVEVNFISMASDRFQLVYQIDAR
>CP025990.1|AUS77428.1|698587_698779_+|DUF397-domain-containing-protein
MRTKLTNWYTSTYSNGGGGACVEVGSAPDLVGIRDSKNRDGGVLIVDHRSFTRFITAIKSERY
>CP025990.1|AUS77427.1|697747_698566_+|XRE-family-transcriptional-regulator
MRRVCRELRKWRESAGLKATEAAKQLKWSPSKISRIEHAVQAPTSVETLALALTYGVPERDRDRLFAAVTTAQEGGWWSQYSDVLWDAAQDLIELEDEASSVRIFKAQLVPGLFQTGDYFAALSESWLPRPTAEVSRQRSFIRETRQQRLTSTNPLHVHAVLWEPLLHGAVGGPEVMRGQLRRLLELAELPHVRIQVLPTGAGAHPALGTEFDLLGFEENHLDDVVYFETLNRGDYVEEQTSVQRHKDSFVALQSRALSDSESTKLIKRLSS
>CP025990.1|AUS77426.1|696824_697040_-|hypothetical-protein
MVLEMALGALIALVGLWVVERLDRWFGPAIRMALRVRRARRTTRQALASVGMTRPTSTRRPFRATGSRSAR
>CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator
MAEDRDSCELLCLDLPHAEAIRADLPGLDEVEPAAAVARALGDPTRLRIAAAFREGGELCVCDASWIVGHARNLVSHHLRQLKSVGLVSSRRDGKLVMYRLTERGHTLVGIILGAEPPAPAETTASARTGVSPHVGG
>CP025990.1|AUS81409.1|713372_714170_-|ABC-transporter-permease
MSEQSTLSPPAPRSAGVPPRIGIWLSYGNLLRWMMAQTGAMLPFVIVVQALLAAGIIIGFGFVIPDIDTSSAQFLSTGTPTVLLMFIGLVMVPHSVAQARTTGTFTYLRSLPVPRPLLLMADLAIWLLVALPSVAVAVVVAHLRYGFGYSFDWPVLLTASILAAVTATAVGYAIAVSLPPLITQLVTQVLVFFVMLFSPVTFPASQLPTWFQAVHDVLPFRAAADLLRAGLLADTYTASWRDLVVLLAWCALGVAVGIRALTRRN
>CP025990.1|AUS77437.1|714162_715152_-|ABC-transporter-ATP-binding-protein
MGGAVLEVDNLTRRFGAVVANDGIGLRVRPGEVVGLLGHNGAGKTTLVSQVVGLLRPEDGSIRVAGTDAVAEPATARRAVALQPQAQAPLDGLTPKMAIEIAGRLRGMSRADARAGARALADELDIGEWFDRPATPDGGGLSGGVRRLTAFAMAAVAPVPLIVLDEPTNDVDAARRRRLWKVVRRLGDEGAGVLLVTHNVTEAERVVDALVILDHGRVVAAGSPSRLRGSSDADLQLELSLHPDGEDPSESLAQAPIPINRRVRVGRRVLLTLAAVDAEAAVAWATALRRTERIDGYSLAPATLEDAYLAATSSANTNTTTRTEDAADV
>CP025990.1|AUS77438.1|715242_715959_+|TetR-family-transcriptional-regulator
MADARSAPPPRTRRTQAERRRETREALVIAALNAFARDGYHTASLEGIAGEAGFSKGAVYSNFNGKSDLFLAAMDYNLETLNGGGWNPLRKVGAATTAASEPGAADMDVAGLVRGFGLATLEFIATAARDDELVKALRERMRRMIDAYGRIATEARPDTERLPSDDVARLMAALDQGVSVLALSGITEMDGALTRVGLHRLVNPLEAAAEPAPERDGQGEPLADIPRVQRLIGDILGT
>CP025990.1|AUS77439.1|716773_717568_-|aminoglycoside-phosphotransferase
METDSAPPRNRVELTSGWDSAAVLVDGRWLERRPRRPEVAAALLRESRLLPWLAGRLPIRVPTPTVVQADPIVVRHELVPGRPISEFTAEQGAALGGFLAALHVVDPVEAVAHGLFTRRATRQERSGLLLRLTSEVVPLLPTVHRPRAERLLSVVASLPADHVVHGDLGPEHVLTTNGVITGVIDFGDVHLGDPAIDLAWALYGTPEHFARALVAAYHPSQDMVERALVWHQLGPWHEVLHGLDTGDGALVDSGIAGVLCRLGS
>CP025990.1|AUS77440.1|719760_721710_+|DNA-helicase-UvrD
MISARERRHQRLWKVLAEHHATLSQLPRWGQQALGELLHRYSSGVRLLVPSPSGGALPIRTDRDLDAYVVGPFGVAALLSVDRRPDDDQIRRLHRGAERLLGAIPLDFGRRIASVRMIVVRPDHLTDLRTNGRYLVRTAADVPTLVADRDYQVLSGASAVDLAGRIAAALPDHVLVDLPETAPPPEEGSLFGAAGLRESSLRRAVNGPFAEWLTYLDETQLRLVHRQYNGPARISGPAGTGKTVVALHRLRRIARETTGPLLLTTLVTTLLRTHATSFRRLAPEVADRVRVENLHLWARQFLEERGRHVRNDHDKVSTCFFLAWSKVNRQTDLPRVNANPQYWREEIDHVIKGRGINDLAEYQRANRRGRGIAGGGLDAGRREQVWQLHQAYQRNLAERGLTDHNDVLVLATEEVRERPLAEPFAAVVVDEVQDLPQVGLRLLHTLVGDRPDGLLLVGDGQQQVYPGGWRLIDAGIHVQGRGETLRVNYRNTRAVLAAAQDVPAPNQLDEEDGAPGATLREVTATLAGGTVHRWSGPAEELEQALVTEAKVVSEAHEETAVLLGSNDDVSQAIRWLRQAGVLAMPLKDYDGTQSGVKVGTVHRAKGMEFGAVLVVLRGTEDDQDASLMDRRLLVAITRARDHAWLATVR
>CP025990.1|AUS77441.1|721826_724409_+|hypothetical-protein
MVFRFRCPTRNGVRSSRPPERQRSRPLPGGSAGRRNFPGKAWPATRRMREYGKGSLVRTGDTVSVSMRKDGHMPESGVVTLVGRWLASNGWSPAQGRLLITPLRRVVENGKTALVPDDTFSVELVNGRIPHRVTCPVDLDDAVETLLHVEEHVLGMRVRTKVVRVEGPVVDLPRAVPVSLSVEERAVVRAATSGAPLSEAGSPVAAMAAAGAGGGEAPPRPEAPLRPVAPAHRGTIGLGTAGASLLTGFAGQLGGASSPPGTGEVRPARATVPGLWQWGRAWSQTGLRKVRVVAVGSSSTQGVGASHIERSFVSRLGQILGEPGRHYPAADGGWLSSGVPLIVDADLGFRSRRLLGGEWIERDLPSGTTLLTVFHGQGSNNGSFEVSVDGGAPVSVIPDRSGQADRADGEWTSPPLPPGTRTVRITAREAVTISGVYAHTDSAGTGIQVFIAGKGGTQSGNYLPSRIMGSHCDRVARLDPDLIVIQLGANDYAAGVAPEVYAERMRQQLNLYRTVCSRRPSILLLHTFRRFDVTTPAHRWEDYARAAHQLAKELDDVAVIDVSAHFPVTQDVDDADMDLVHVDRIHLSDAGHGLTARLIADQLRLPLVPRSAPPTPDHPVGRDPAANRGVVVALRASELDGGPGDRIAEFTPHQGTEPGPRQEREDARPELRVEAGRWFLRFDRVDGPRWMQSPAWSRAHTPPVTVFLVARPRDVHGTWVSGHSGSYLAWFTAGNPLCHMMCGAGGLSAPDAATVWTGVGRWNVFAAVFDGERSRHLTYGHEVTRIVTGTGPAASLPGLTLATNAATTGVYADIDIADLVVVDRAFTDTELQGGADWLARHYRLDQAGRTSVTAGPLSAG
>CP025990.1|AUS77442.1|724589_724931_+|hypothetical-protein
MPGTVRVVTATAALWVRTDHGLVRADAFTHVRVAGGKLVVSNGVPVGVEGTFRGMGKVSTDLYALCEVGKDDAEDIAERFVRFLARHQAAGRAGLISADGDGAFHLDAVDTAG
>CP025990.1|AUS77443.1|725184_725580_+|hypothetical-protein
MSELVEFDDLAQLRVLLRAAMVLKFDIPEASAGPLAGSPVFASAVHRLRDALVAALESTGSSAAARTEAGWYRLAEHPHQWELLARRASNHPRWAELDGKARRDWVETLAAPLVVDEESLTAIITRADGER
>CP025990.1|AUS77444.1|726889_728992_+|hypothetical-protein
MAARAIMAATVVATTFSAPHAVASPSDGGIGTPSHGTTVADAIRTGERSRSEVPRMALEDGGDSHLDQPSELSMQGGAVACDVGAARPWLSTTTPRLRARVSSQNGGLLTAHFEWGLVGQEATGSRSVSRTPSGSSAEITVPEGQLSEGETYFWRVRAHDGVAYSPYSQPCEMVIDATAPHSPPTVSSTTYPRDKWAGGMGIPGEFTFEANGVDDVVRYLYSTVPPSLTTPAPTDGLGGPATVEITPTSDGPYTLSVRSQDRAGNLSPVTYYSFLVAGRTPAVSHWKFDEFDGTTTPDSSGNGHAASVAGTVRWSDGHAGNAPHFDGATGHLTTDSAGVRTDNSFAVTAWVQLTGKELSRTAVSQDGAQSSGYHLHYSRDEDRWAFSLPSADGGSSTTARALSVEPADTDGRWTHLAGVYEAHRERIILYVDGVEQSSAEVSSHWNATGSVRIGAAQSGGRTSDFWAGAVDEVRVYERALAADEVAEIFNQVVLKGHWGLEESADGTIPDESQWNHPGVVRGGATWREDDYMATTVLELDGQSGHVADIPAAVDTSKSFSVSVWVYSEDLGTSSQTAISLGNGAQLQYRASSGRWAFVLPGPPETEGPIVAESLRSAREGQWTHLVGLYDSAERQVSLHVDARLDKKVDHVYSASSEDGIQIGRAESDASYWRGSVSDVRVFSGVLSQPRISDLAFPRRW

Crispr_ID: CP025990_12

• CRISPR_ID: CP025990_12
• CRISPR_location: 718127-718684
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers
• Cas_protein_info: csa3,WYL

Consensus repeat of CP025990_12

Consensus_repeat	Method
GGTCCTCATCGCTCCTACGAGGAGT	CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CRISPRCasFinder

spacers of CP025990_12

>12.1|718152|42|CP025990|CRT
TCCAACATCTCGCGCATCAGCGTGGATGCCTCCCAGAGCCAA
>12.2|718219|39|CP025990|CRT
TCCAACTTGATGTTCCAGGACCGTCCAACCTTGGTGGCG
>12.3|718283|40|CP025990|CRT
TCCAACCCGTGGATGACCAGCGCCTCGGTGTCGTCCCACG
>12.4|718348|42|CP025990|CRT
TCCAACCGTCATCTACGGTGACAGCGGATTTGTCCGGGGCCT
>12.5|718415|41|CP025990|CRT
TCCAACGCCACGGACCTGCGTGCCGCCGCCGCAGAGGACGA
>12.6|718481|41|CP025990|CRT
CCCAACTCGGACCGGCTGGCCTCCTGCTCTGTGAGCCAACG
>12.7|718547|40|CP025990|CRT
CCCAACGCGTAGCGGTGGCGGCACACCGTGACCGTGGCAC
>12.8|718612|42|CP025990|CRT
TCCAACTCGCGGTCCCGCGCCCGTTGCCGGCTGGCGGCGTCG
>12.9|718158|37|CP025990|PILER-CR,CRISPRCasFinder
ATCTCGCGCATCAGCGTGGATGCCTCCCAGAGCCAAG
>12.10|718225|34|CP025990|PILER-CR,CRISPRCasFinder
TTGATGTTCCAGGACCGTCCAACCTTGGTGGCGG
>12.11|718289|35|CP025990|PILER-CR,CRISPRCasFinder
CCGTGGATGACCAGCGCCTCGGTGTCGTCCCACGA
>12.12|718354|37|CP025990|PILER-CR,CRISPRCasFinder
CGTCATCTACGGTGACAGCGGATTTGTCCGGGGCCTG
>12.13|718421|36|CP025990|PILER-CR,CRISPRCasFinder
GCCACGGACCTGCGTGCCGCCGCCGCAGAGGACGAG
>12.14|718487|36|CP025990|PILER-CR,CRISPRCasFinder
TCGGACCGGCTGGCCTCCTGCTCTGTGAGCCAACGC
>12.15|718553|35|CP025990|PILER-CR,CRISPRCasFinder
GCGTAGCGGTGGCGGCACACCGTGACCGTGGCACG
>12.16|718618|37|CP025990|CRISPRCasFinder
TCGCGGTCCCGCGCCCGTTGCCGGCTGGCGGCGTCGG

CRISPR arrays and Neighbor proteins around CP025990_12

CRISPR arrays

The CRISPR arrays of CP025990_12

>merge|CP025990|12|718127-718684|CRT,PILER-CR,CRISPRCasFinder
GGTCCTCATCGCTCCTACGAGGAGTTCCAACATCTCGCGCATCAGCGTGGATGCCTCCCAGAGCCAAGGTCCTCATCGCTCCTACGAGGAGTTCCAACTTGATGTTCCAGGACCGTCCAACCTTGGTGGCGGGTCCTCATCGCTCCTACGAGGAGTTCCAACCCGTGGATGACCAGCGCCTCGGTGTCGTCCCACGAGTCCTCATCGCTCCTACGAGGAGTTCCAACCGTCATCTACGGTGACAGCGGATTTGTCCGGGGCCTGGTCCTCATCGCTCCTACGAGGAGTTCCAACGCCACGGACCTGCGTGCCGCCGCCGCAGAGGACGAGGTCCTCATCGCTCCTACGAGGAGTCCCAACTCGGACCGGCTGGCCTCCTGCTCTGTGAGCCAACGCGTCCTCATCGCTCCTACGAGGAGTCCCAACGCGTAGCGGTGGCGGCACACCGTGACCGTGGCACGGTCCTCATCGCTCCTACGAGGAGTTCCAACTCGCGGTCCCGCGCCCGTTGCCGGCTGGCGGCGTCGGGTCCTCATCGCTCCTACGAGGTTCCAGCTG

>CP025990|12|11|718127-718678|CRT
GGTCCTCATCGCTCCTACGAGGAGT	TCCAACATCTCGCGCATCAGCGTGGATGCCTCCCAGAGCCAA
GGTCCTCATCGCTCCTACGAGGAGT	TCCAACTTGATGTTCCAGGACCGTCCAACCTTGGTGGCG
GGTCCTCATCGCTCCTACGAGGAGT	TCCAACCCGTGGATGACCAGCGCCTCGGTGTCGTCCCACG
AGTCCTCATCGCTCCTACGAGGAGT	TCCAACCGTCATCTACGGTGACAGCGGATTTGTCCGGGGCCT
GGTCCTCATCGCTCCTACGAGGAGT	TCCAACGCCACGGACCTGCGTGCCGCCGCCGCAGAGGACGA
GGTCCTCATCGCTCCTACGAGGAGT	CCCAACTCGGACCGGCTGGCCTCCTGCTCTGTGAGCCAACG
CGTCCTCATCGCTCCTACGAGGAGT	CCCAACGCGTAGCGGTGGCGGCACACCGTGACCGTGGCAC
GGTCCTCATCGCTCCTACGAGGAGT	TCCAACTCGCGGTCCCGCGCCCGTTGCCGGCTGGCGGCGTCG
GGTCCTCATCGCTCCTACGAGGTTC

>CP025990|12|11|718128-718617|PILER-CR
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ATCTCGCGCATCAGCGTGGATGCCTCCCAGAGCCAAG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	TTGATGTTCCAGGACCGTCCAACCTTGGTGGCGG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CCGTGGATGACCAGCGCCTCGGTGTCGTCCCACGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGTCATCTACGGTGACAGCGGATTTGTCCGGGGCCTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCACGGACCTGCGTGCCGCCGCCGCAGAGGACGAG
GTCCTCATCGCTCCTACGAGGAGTCCCAAC	TCGGACCGGCTGGCCTCCTGCTCTGTGAGCCAACGC
GTCCTCATCGCTCCTACGAGGAGTCCCAAC	GCGTAGCGGTGGCGGCACACCGTGACCGTGGCACG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC

>CP025990|12|11|718128-718684|CRISPRCasFinder
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	ATCTCGCGCATCAGCGTGGATGCCTCCCAGAGCCAAG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	TTGATGTTCCAGGACCGTCCAACCTTGGTGGCGG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CCGTGGATGACCAGCGCCTCGGTGTCGTCCCACGA
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	CGTCATCTACGGTGACAGCGGATTTGTCCGGGGCCTG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	GCCACGGACCTGCGTGCCGCCGCCGCAGAGGACGAG
GTCCTCATCGCTCCTACGAGGAGTCCCAAC	TCGGACCGGCTGGCCTCCTGCTCTGTGAGCCAACGC
GTCCTCATCGCTCCTACGAGGAGTCCCAAC	GCGTAGCGGTGGCGGCACACCGTGACCGTGGCACG
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	TCGCGGTCCCGCGCCCGTTGCCGGCTGGCGGCGTCGG
GTCCTCATCGCTCCTACGAGGTTCCAGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77437.1|714162_715152_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
CP025990.1|AUS77432.1|704556_706800_-|daunorubicin-resistance-protein-DrrC	unknown	unknown	gnl|CDD|223256
CP025990.1|AUS77445.1|730121_732584_-|beta-mannosidase	unknown	unknown	gnl|CDD|225789
CP025990.1|AUS77444.1|726889_728992_+|hypothetical-protein	unknown	unknown	gnl|CDD|379155
CP025990.1|AUS77441.1|721826_724409_+|hypothetical-protein	unknown	unknown	gnl|CDD|379207
CP025990.1|AUS81410.1|734827_735700_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
CP025990.1|AUS77435.1|710497_711469_-|EamA-family-transporter	unknown	unknown	gnl|CDD|183142
CP025990.1|AUS77439.1|716773_717568_-|aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|270701
CP025990.1|AUS77434.1|708078_709971_-|hypothetical-protein	unknown	unknown	gnl|CDD|223496
CP025990.1|AUS77431.1|703152_704226_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	unknown	unknown	gnl|CDD|225316
CP025990.1|AUS77440.1|719760_721710_+|DNA-helicase-UvrD	unknown	unknown	gnl|CDD|223288
CP025990.1|AUS81409.1|713372_714170_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP025990.1|AUS77438.1|715242_715959_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
CP025990.1|AUS77447.1|733697_734828_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
CP025990.1|AUS77448.1|735777_736773_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
CP025990.1|AUS77442.1|724589_724931_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77446.1|732651_733701_-|dipeptide/oligopeptide/nickel-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
CP025990.1|AUS77443.1|725184_725580_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.8e-15	51.5	0.0
CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	2.6e-53	176.2	0.6

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77437.1|714162_715152_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.3076e-62
CP025990.1|AUS77432.1|704556_706800_-|daunorubicin-resistance-protein-DrrC	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
CP025990.1|AUS77444.1|726889_728992_+|hypothetical-protein	gnl|CDD|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	4.56082e-25
CP025990.1|AUS77441.1|721826_724409_+|hypothetical-protein	gnl|CDD|379207	pfam13472, Lipase_GDSL_2, GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.	8.57046e-14
CP025990.1|AUS81410.1|734827_735700_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.2599e-72
CP025990.1|AUS77435.1|710497_711469_-|EamA-family-transporter	gnl|CDD|183142	PRK11453, PRK11453, O-acetylserine/cysteine exporter.	2.78688e-60
CP025990.1|AUS77439.1|716773_717568_-|aminoglycoside-phosphotransferase	gnl|CDD|270701	cd05152, MPH2', Macrolide 2'-Phosphotransferase. MPH2' catalyzes the transfer of the gamma-phosphoryl group from ATP to the 2'-hydroxyl of macrolide antibiotics such as erythromycin, clarithromycin, and azithromycin, among others. Macrolides penetrate the bacterial cell and bind to ribosomes, where it interrupts protein elongation, leading ultimately to the demise of the bacterium. Phosphorylation of macrolides leads to their inactivation. Based on substrate specificity and amino acid sequence, MPH2' is divided into types I and II, encoded by mphA and mphB genes, respectively. MPH2'I inactivates 14-membered ring macrolides while MPH2'II inactivates both 14- and 16-membered ring macrolides. Enzymatic inactivation of macrolides has been reported as a mechanism for bacterial resistance in clinical samples. MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.11772e-25
CP025990.1|AUS77434.1|708078_709971_-|hypothetical-protein	gnl|CDD|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	4.56469e-05
CP025990.1|AUS77431.1|703152_704226_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	gnl|CDD|225316	COG2518, Pcm, Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones].	3.24705e-28
CP025990.1|AUS77440.1|719760_721710_+|DNA-helicase-UvrD	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.56819e-09
CP025990.1|AUS81409.1|713372_714170_-|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.44904e-08
CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.10456e-45
CP025990.1|AUS77438.1|715242_715959_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.09316e-09
CP025990.1|AUS77447.1|733697_734828_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.98304e-143
CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	8.85964e-15
CP025990.1|AUS77448.1|735777_736773_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.42202e-101
CP025990.1|AUS77446.1|732651_733701_-|dipeptide/oligopeptide/nickel-ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	3.59824e-105
CP025990.1|AUS77445.1|730121_732584_-|beta-mannosidase	gnl|CDD|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	6.50858e-81

Protein sequences

>CP025990.1|AUS77439.1|716773_717568_-|aminoglycoside-phosphotransferase
METDSAPPRNRVELTSGWDSAAVLVDGRWLERRPRRPEVAAALLRESRLLPWLAGRLPIRVPTPTVVQADPIVVRHELVPGRPISEFTAEQGAALGGFLAALHVVDPVEAVAHGLFTRRATRQERSGLLLRLTSEVVPLLPTVHRPRAERLLSVVASLPADHVVHGDLGPEHVLTTNGVITGVIDFGDVHLGDPAIDLAWALYGTPEHFARALVAAYHPSQDMVERALVWHQLGPWHEVLHGLDTGDGALVDSGIAGVLCRLGS
>CP025990.1|AUS77438.1|715242_715959_+|TetR-family-transcriptional-regulator
MADARSAPPPRTRRTQAERRRETREALVIAALNAFARDGYHTASLEGIAGEAGFSKGAVYSNFNGKSDLFLAAMDYNLETLNGGGWNPLRKVGAATTAASEPGAADMDVAGLVRGFGLATLEFIATAARDDELVKALRERMRRMIDAYGRIATEARPDTERLPSDDVARLMAALDQGVSVLALSGITEMDGALTRVGLHRLVNPLEAAAEPAPERDGQGEPLADIPRVQRLIGDILGT
>CP025990.1|AUS77437.1|714162_715152_-|ABC-transporter-ATP-binding-protein
MGGAVLEVDNLTRRFGAVVANDGIGLRVRPGEVVGLLGHNGAGKTTLVSQVVGLLRPEDGSIRVAGTDAVAEPATARRAVALQPQAQAPLDGLTPKMAIEIAGRLRGMSRADARAGARALADELDIGEWFDRPATPDGGGLSGGVRRLTAFAMAAVAPVPLIVLDEPTNDVDAARRRRLWKVVRRLGDEGAGVLLVTHNVTEAERVVDALVILDHGRVVAAGSPSRLRGSSDADLQLELSLHPDGEDPSESLAQAPIPINRRVRVGRRVLLTLAAVDAEAAVAWATALRRTERIDGYSLAPATLEDAYLAATSSANTNTTTRTEDAADV
>CP025990.1|AUS81409.1|713372_714170_-|ABC-transporter-permease
MSEQSTLSPPAPRSAGVPPRIGIWLSYGNLLRWMMAQTGAMLPFVIVVQALLAAGIIIGFGFVIPDIDTSSAQFLSTGTPTVLLMFIGLVMVPHSVAQARTTGTFTYLRSLPVPRPLLLMADLAIWLLVALPSVAVAVVVAHLRYGFGYSFDWPVLLTASILAAVTATAVGYAIAVSLPPLITQLVTQVLVFFVMLFSPVTFPASQLPTWFQAVHDVLPFRAAADLLRAGLLADTYTASWRDLVVLLAWCALGVAVGIRALTRRN
>CP025990.1|AUS77436.1|712483_712897_-|transcriptional-regulator
MAEDRDSCELLCLDLPHAEAIRADLPGLDEVEPAAAVARALGDPTRLRIAAAFREGGELCVCDASWIVGHARNLVSHHLRQLKSVGLVSSRRDGKLVMYRLTERGHTLVGIILGAEPPAPAETTASARTGVSPHVGG
>CP025990.1|AUS77435.1|710497_711469_-|EamA-family-transporter
MPLRHCLLALSVAVVWGLNFVAISASLEHFPPMFLVALRFAVVAIPTVLFVPAPGVPLRWLLGYGCGFGIVQFLFLFWGMAVGMPTGLASLVLQSSAPFTVLLGATVLRERISARQLAGILVGVGGLAVVGWYRAETASVVPFLLTVAGAFGWAVGNICGRLAKPSSPVRLMLWMCVVPPLPMFALAFVVEGPTRIGVSLSTLGAPGAWAALLGLAYTVLIAGVLGSGAWTWLLARHPAGVVAPFSMLAPVVGMTAAWLVLRETVAAWELLGGLLIVGGVLLGCVGRQGTGTRLPRVAPPGAPEPSEARVAGNGRPVNPRPPG
>CP025990.1|AUS77434.1|708078_709971_-|hypothetical-protein
MAVVGPIDRGKTSMIECVDFLFGRTVQFRGAVDQRLRAVQAQIQIGDGTYRVTRDRDHPGTVWVEEADGTPVGHFLLRSQDEKPSWSTWLLMRLGLDEMFASVRLPGDRRLSFAEDLLPYLHIRQEDIDRFVVRPPSRTTPRLAVFKLLLHLTTPETERLAGAITDTRNRITLQRRKARDLARFLRSSDATSEKALDAELVTLREREREARDVVARLRAAANASATHMAHLHRQVDEARARLSEAEDTVERDHRRHQEARSKVKALRDSLSHVDAVEDVEPCEREQLTYAFDACPACRQGLGERVVPPGHCGVCVLPLPGAAVEAERARLRKMEEAAATALATADQDLRGSGEVVRRARADLDTARQRVDQHLAASTSPHVDAIAAATGELAALSAQISALTRLRAPHDQLRRLERDTERDARKLKEMRERHLQLSAQLVRPGDALERLNSLFRQIVHAFDLPWATGRARLDPETWTPLVDDQDFGQRGGGSRTAVSVAYSLALLLYALEQPADFHLPHLLILDSPQKNLGRNSHDQALAARMYRWMADYLQDRAAALSGTTSGQRYRDFQLVIVDNAIPAEVRDSFRPTVTFDEDTGFVRELEHPHGPPLPAEQLRFGDDVGIELGSTA
>CP025990.1|AUS77433.1|706862_707822_+|transcriptional-regulator
MADVTQRSLALLAALQTGRAFTGGELARHLDVSPRTLRRDIDRLRGYGYPVETQPGPGGYYRLATGNSMPPLLLDDDEAAATLLALAALAATGSAEQGSLDAAATSAYGKVDQYLPARLRPRVAALRASLETDQTAAPSTSTETLSTLGTAIQRSHVVAFDYTTARGTTSSRRVEPHRQVHLLHRWYLLAWDLGPEDWRVFRVDRISDARDAGRSFRPRPLPAGGGVEHVRQAVTRARQRVVVTIEAPIAKVADALRHQYTELTPLDADRTRIVLMPESWQWLVLNIALVDADFTIEEPASMREQCQRFGARLAGGGQG
>CP025990.1|AUS77432.1|704556_706800_-|daunorubicin-resistance-protein-DrrC
MSQQRNIRVRGARTNNLKSLDVDVPRGQLVVFVGLSGSGKSSLVFDTIAAEAGHQLNETFPPFVRNRMTKWTRPEVTEISGLSPAVVIGQRRVGGNSRSTVGTYTDAWSYLRLIFSRLSTPHVGESNRFSFNDPTGMCPTCSGLGEVVVTAVDRVVDMDRSLEDGAVRLPGFVQGGYWYSLYADIGSFDATTPLRDWSEDQRQALLYGGEHAERLDPRPPKGFEGVVERFERIYLNTSEDLSERKRETLAQFTRSDLCPDCHGDRLNEESRSATVLGRTIGAMARMEVSDLADLVTGVTEPSVRPAVAALKDRLDALVTIGLGYLHLGRPTPTLSGGESQRIKTVKHLGSSLMEMLYVFDEPTVGLHPHDVSAMITLLRQLCDKGNSVLVVEHDPAVMAAADQVVEIGPRAGEHGGALVFQGPFSELGAAGTATSVELSRTRRPREEPRTPTGQVVVADACRNNLRKVTVEIPTGVMTVLTGVAGSGKSSLARELVNQHDAIVIDQRPVSASRRSTPITYTGVAAPIRKLFARRNGVAASLFSANSEGGCPDCGGTGVIYTDLAFMDGQETVCETCQGRRFTPDVLRYTVDGLSIADVEDLTIEEAIRRLPDRAITKALSHLDKVGLGYLRLGQPLSTLSGGECQRVKVAKELREASMPTLYVLDEPTTGLHLADIDTLLGLLDDLVEHGHGVVVIEHNLDVIRHADWLIDLGPGPGRHGGRVLYEGPVTGVGDTPTGRALREAFPS
>CP025990.1|AUS77431.1|703152_704226_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase
MVHSWSLFLLGGVVVTIAPTVASVAGTIPETHYSHHGGRGHTPMRSNPLVIHRELTLLDVHPAQRVCEIGTGSGYSGALLSSLVGEDGRVVSVVSVDIDPYLVQWARCAHRERGVRNVRCVVGDGRQGFAAEAPYDRLVAWCTPPHLPKAWVDQSQVGGVIVTPLPVARVPQITVVAEILVDEDRIPRVQRVLHGGYMETVSSPCDPDTPTRLVDWEYRLPSAAWRSVGWRKEDNELRDGARGALDRLLARSSIRETVGEEDIDWGSWRTWAAATDDHYLTAVGWPSGGIAVGHSTPESVAVLRHDGTILADRRASPSLRIVRDWFRAWDRAGRPAVEEYEGTLHPQQEGWRLRLSR
>CP025990.1|AUS77440.1|719760_721710_+|DNA-helicase-UvrD
MISARERRHQRLWKVLAEHHATLSQLPRWGQQALGELLHRYSSGVRLLVPSPSGGALPIRTDRDLDAYVVGPFGVAALLSVDRRPDDDQIRRLHRGAERLLGAIPLDFGRRIASVRMIVVRPDHLTDLRTNGRYLVRTAADVPTLVADRDYQVLSGASAVDLAGRIAAALPDHVLVDLPETAPPPEEGSLFGAAGLRESSLRRAVNGPFAEWLTYLDETQLRLVHRQYNGPARISGPAGTGKTVVALHRLRRIARETTGPLLLTTLVTTLLRTHATSFRRLAPEVADRVRVENLHLWARQFLEERGRHVRNDHDKVSTCFFLAWSKVNRQTDLPRVNANPQYWREEIDHVIKGRGINDLAEYQRANRRGRGIAGGGLDAGRREQVWQLHQAYQRNLAERGLTDHNDVLVLATEEVRERPLAEPFAAVVVDEVQDLPQVGLRLLHTLVGDRPDGLLLVGDGQQQVYPGGWRLIDAGIHVQGRGETLRVNYRNTRAVLAAAQDVPAPNQLDEEDGAPGATLREVTATLAGGTVHRWSGPAEELEQALVTEAKVVSEAHEETAVLLGSNDDVSQAIRWLRQAGVLAMPLKDYDGTQSGVKVGTVHRAKGMEFGAVLVVLRGTEDDQDASLMDRRLLVAITRARDHAWLATVR
>CP025990.1|AUS77441.1|721826_724409_+|hypothetical-protein
MVFRFRCPTRNGVRSSRPPERQRSRPLPGGSAGRRNFPGKAWPATRRMREYGKGSLVRTGDTVSVSMRKDGHMPESGVVTLVGRWLASNGWSPAQGRLLITPLRRVVENGKTALVPDDTFSVELVNGRIPHRVTCPVDLDDAVETLLHVEEHVLGMRVRTKVVRVEGPVVDLPRAVPVSLSVEERAVVRAATSGAPLSEAGSPVAAMAAAGAGGGEAPPRPEAPLRPVAPAHRGTIGLGTAGASLLTGFAGQLGGASSPPGTGEVRPARATVPGLWQWGRAWSQTGLRKVRVVAVGSSSTQGVGASHIERSFVSRLGQILGEPGRHYPAADGGWLSSGVPLIVDADLGFRSRRLLGGEWIERDLPSGTTLLTVFHGQGSNNGSFEVSVDGGAPVSVIPDRSGQADRADGEWTSPPLPPGTRTVRITAREAVTISGVYAHTDSAGTGIQVFIAGKGGTQSGNYLPSRIMGSHCDRVARLDPDLIVIQLGANDYAAGVAPEVYAERMRQQLNLYRTVCSRRPSILLLHTFRRFDVTTPAHRWEDYARAAHQLAKELDDVAVIDVSAHFPVTQDVDDADMDLVHVDRIHLSDAGHGLTARLIADQLRLPLVPRSAPPTPDHPVGRDPAANRGVVVALRASELDGGPGDRIAEFTPHQGTEPGPRQEREDARPELRVEAGRWFLRFDRVDGPRWMQSPAWSRAHTPPVTVFLVARPRDVHGTWVSGHSGSYLAWFTAGNPLCHMMCGAGGLSAPDAATVWTGVGRWNVFAAVFDGERSRHLTYGHEVTRIVTGTGPAASLPGLTLATNAATTGVYADIDIADLVVVDRAFTDTELQGGADWLARHYRLDQAGRTSVTAGPLSAG
>CP025990.1|AUS77442.1|724589_724931_+|hypothetical-protein
MPGTVRVVTATAALWVRTDHGLVRADAFTHVRVAGGKLVVSNGVPVGVEGTFRGMGKVSTDLYALCEVGKDDAEDIAERFVRFLARHQAAGRAGLISADGDGAFHLDAVDTAG
>CP025990.1|AUS77443.1|725184_725580_+|hypothetical-protein
MSELVEFDDLAQLRVLLRAAMVLKFDIPEASAGPLAGSPVFASAVHRLRDALVAALESTGSSAAARTEAGWYRLAEHPHQWELLARRASNHPRWAELDGKARRDWVETLAAPLVVDEESLTAIITRADGER
>CP025990.1|AUS77444.1|726889_728992_+|hypothetical-protein
MAARAIMAATVVATTFSAPHAVASPSDGGIGTPSHGTTVADAIRTGERSRSEVPRMALEDGGDSHLDQPSELSMQGGAVACDVGAARPWLSTTTPRLRARVSSQNGGLLTAHFEWGLVGQEATGSRSVSRTPSGSSAEITVPEGQLSEGETYFWRVRAHDGVAYSPYSQPCEMVIDATAPHSPPTVSSTTYPRDKWAGGMGIPGEFTFEANGVDDVVRYLYSTVPPSLTTPAPTDGLGGPATVEITPTSDGPYTLSVRSQDRAGNLSPVTYYSFLVAGRTPAVSHWKFDEFDGTTTPDSSGNGHAASVAGTVRWSDGHAGNAPHFDGATGHLTTDSAGVRTDNSFAVTAWVQLTGKELSRTAVSQDGAQSSGYHLHYSRDEDRWAFSLPSADGGSSTTARALSVEPADTDGRWTHLAGVYEAHRERIILYVDGVEQSSAEVSSHWNATGSVRIGAAQSGGRTSDFWAGAVDEVRVYERALAADEVAEIFNQVVLKGHWGLEESADGTIPDESQWNHPGVVRGGATWREDDYMATTVLELDGQSGHVADIPAAVDTSKSFSVSVWVYSEDLGTSSQTAISLGNGAQLQYRASSGRWAFVLPGPPETEGPIVAESLRSAREGQWTHLVGLYDSAERQVSLHVDARLDKKVDHVYSASSEDGIQIGRAESDASYWRGSVSDVRVFSGVLSQPRISDLAFPRRW
>CP025990.1|AUS77445.1|730121_732584_-|beta-mannosidase
MRMELHDGWTVRAVRGPAPDALADREVPATVPGCVHTDLLALDLIPDPYQDRNEAELHWIGRTDWRYRTTFDWEPGDGTERVDLACAGLDTIARLELNGHVIAGTANMHRAYRFDVTDQLRAGPNELTVTFTSALDHADRVRELLGHRPHTNHHPYNQIRKMACNFGWDWGPDLVTAGIWRPLALERWHGARLTSVRPLATVDADGDGVVHVHVDVDRAPGHDDELPVTVHVGVVAAAGVVPAGATTTTIEARVDQPRRWWPHGYGDQHRYPVDVALTVEDQPTPDNGDLTTWAGEVGFRSVRLDTEPDEHGTPFTFVVNDVPVFARGVNWIPDDCFPHRVDAARYRQRLAQARDAGVNLVRVWGGGIYESDDFYDACDELGILTWQDFLFACAAYPEEEPLRSEVEAEARDAITRLAPHPSLVLWNGNNENIWGHHDWGWRDQLGDRTWGAGYYHRLLPDLLAELDPTRPYSAGSPWSFSHDIHPNDPAHGATHIWDVWNQRDYTAYRDHVPRFVAEFGFQGPPAYATLRASLSDDPLRPDSPGMLAHQKAEDGNGKLARGLAEHFPEPQDFDDWFWATQLNQARALRFGVEHFRSHAPRCAGTVWWQLNDCWPVTSWSVVDGQGRRKPAWYALRAAYQDRLVTVRPRPGGLAAVLCNETDEPWTTRLVVARTAFAGAVLGEVRHQLTVPPRAVHEEPLPDTITTATDPAAELLVATAGDVRATWFHLPDLELALPVPELTTAVEALEDGYRVEVTAGTLVRDLALLADRVASDAEVDDMLGTLLPGESTSIVVRTALPVDPEDLVAPLVLRSANQLLR
>CP025990.1|AUS77446.1|732651_733701_-|dipeptide/oligopeptide/nickel-ABC-transporter-ATP-binding-protein
MSRLAAHGLVREFRLPGRSRRHPLRAVSDVSLELHAGETVALVGESGSGKSTVARILARLDTPDAGTILLDGQPATPGRRGLRHHHRQVQIVFQDPFASLNPFHTVDHHLRRPLRLHHPALGRAEEDERIHHLLDRVNLVPAGRVAAAHPHELSGGQRQRVAIARALACRPGVLLADEPVSMLDVSIRLEILRLLDRLRAEDDLAVLYITHDLATARHFAHRILVMYRGELVESGPSDAVILDPRHPYTRLLAAAAPDPRRRGTSALAGPDLPVTRVEVPGATDAGGCPFLDRCPQAMPRCRLRPPLVPLGGGRTARCWLHAADTDPAGSPPGPATTRPPAPPTARPDP
>CP025990.1|AUS77447.1|733697_734828_-|ABC-transporter-ATP-binding-protein
MGDHHDTGRPVLSVRGLRVDYQLDPPVHAVRDLSLVLRRGEVLGVAGESGCGKSTLAYAVNRLLRPPAEVVGGSVVFHGPDGHDTDVLALTGEALRSFRWRRVAMVFQGAMNALNPVLTIHTQLTDVLAAHEPGSRRRDRARRCAELLSLVGVHPDRARSYPHELSGGMRQRVMIAMALALNPDVLVMDEPTTALDVVVQRDILRELGRLRERFGFALVLITHDLSLLLEISDRIAVMYAGRVVEEGTATRLLTAPRHPYTTGLLGSFPSLTGPRQDMRGIPGQPPDLTQALDHCAFHDRCPHRRDVCAHQRPPLGPAPAAGEHPTPGGGEHPTPGGGAHLVACHAWHPDRYGAPAPTALRHGTFRPTHTAEVVDP
>CP025990.1|AUS81410.1|734827_735700_-|ABC-transporter-permease
MPRDGRARVGLAVIAGFVLVAVVGPFLVTGASGIGPDPLAPPSAQHWLGTTQTGQDVLAQLVVATRGSLLVGALAGLLATVLSIVVGVVGGYVGGRVDEALSLLSNVTLVIPSLPLVILVTHYLDGGGILAISVVIGLTSWAASARVLRAQTRSVRARDHVAASRALGERPWRMVLVEVVPNLLPVIAAQFVFAVIFAILTEAGLSFLGLGGVDHLTWGTMLYFAQNAQALAIGAWWWFIPPGLAIALLGCALSLLNLSLDEVINPRLRGSRSRRDRRAARRPAQPREER
>CP025990.1|AUS77448.1|735777_736773_-|ABC-transporter-permease
MRHLRRKLAFYLVALWAAVTVNFLLPRLMPGDPVDALLSRMQQTGGAVSPEARQALEVMLGSGGQENLAAQYLTYLGNLLRGDFGVSATYFPTPVSTVLTQSLPWTLVLVGLSTVVSFVLGVTLGALVGWRRGRWSDALVPATTFLAAVPYFWLALVLVFVFGATLGLFPLTGGYDYGLEVGFSGPFLASALHHGLLPAITIVLSSVGTWLLGMRNMTVSTMAEDYVLTAQAKGLRPRRVLVTYAARNAVIPSLASFAISLGFVVSGSIVTEAVFSYPGIGFTLLQAVQNNDYPLMQAVFLVITLAVLGANLLVDLLHAVIDPRTRQTGGR

Crispr_ID: CP025990_13

• CRISPR_ID: CP025990_13
• CRISPR_location: 791846-792836
• CRISPR_type: Unclear
• Repeat_type: NA:I-C,III-B
• Spacer_info: 13 spacers
• Cas_protein_info: cas6,WYL

Consensus repeat of CP025990_13

Consensus_repeat	Method
GTTG-------CACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	PILER-CR
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACG	CRISPRCasFinder
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CRT

spacers of CP025990_13

>13.1|791883|38|CP025990|PILER-CR,CRT
GTCGGCGAGGACGACGCCCAAAGAACCCGCGCCGCCCG
>13.2|791958|36|CP025990|PILER-CR,CRT
CTCGGTGTCTCGCGGGGACTCCCCAGCTCAGGAGCT
>13.3|792031|36|CP025990|PILER-CR,CRT
CCCGGCGAGGGCGGCGGGTGGTCGGCGGCCGTTCCC
>13.4|792104|35|CP025990|PILER-CR,CRT
CACCGCATCGCCCTCACCGACATCGACGCCCTCGC
>13.5|792176|34|CP025990|PILER-CR,CRT
CTCCGAGCCACCCCGGAGGGGGACGTCGTGCGGA
>13.6|792247|34|CP025990|PILER-CR,CRT
GAGTGGATGCTCTTGCGCAGCCTCGCTCCTGCGA
>13.7|792318|39|CP025990|PILER-CR,CRT
ACCGGCCCTCACCACCCCGGCGGGTGGCCCGGCGAACGA
>13.8|792394|38|CP025990|PILER-CR,CRT
TGATGACGGTCTCCCAGCTCATCGCCGCCCTGTCCCGG
>13.9|792469|37|CP025990|PILER-CR,CRT
GTCACCTATGTTCTCTATCCGGTCTTGCTGTCCTAGG
>13.10|792543|36|CP025990|PILER-CR,CRT
CTGGTCGCCGCAGGACCGGTGGACGACCGTCGAGTA
>13.11|792616|35|CP025990|PILER-CR,CRT
GAGGCACTCACGGCAGACCCACTCGGGCCGCCCGG
>13.12|792688|36|CP025990|PILER-CR,CRT
GCCTCCTGGCTGGCGTGCTGGCTGGGCCACGCCGCC
>13.13|792761|38|CP025990|PILER-CR,CRT
GGGCGCAACGTGCGCTGCGTGACCTCTCACAGCCTCGT
>13.14|791884|37|CP025990|CRISPRCasFinder
TCGGCGAGGACGACGCCCAAAGAACCCGCGCCGCCCG
>13.15|791959|35|CP025990|CRISPRCasFinder
TCGGTGTCTCGCGGGGACTCCCCAGCTCAGGAGCT
>13.16|792032|35|CP025990|CRISPRCasFinder
CCGGCGAGGGCGGCGGGTGGTCGGCGGCCGTTCCC
>13.17|792105|34|CP025990|CRISPRCasFinder
ACCGCATCGCCCTCACCGACATCGACGCCCTCGC
>13.18|792177|33|CP025990|CRISPRCasFinder
TCCGAGCCACCCCGGAGGGGGACGTCGTGCGGA
>13.19|792248|33|CP025990|CRISPRCasFinder
AGTGGATGCTCTTGCGCAGCCTCGCTCCTGCGA
>13.20|792319|38|CP025990|CRISPRCasFinder
CCGGCCCTCACCACCCCGGCGGGTGGCCCGGCGAACGA
>13.21|792395|37|CP025990|CRISPRCasFinder
GATGACGGTCTCCCAGCTCATCGCCGCCCTGTCCCGG
>13.22|792470|36|CP025990|CRISPRCasFinder
TCACCTATGTTCTCTATCCGGTCTTGCTGTCCTAGG
>13.23|792544|35|CP025990|CRISPRCasFinder
TGGTCGCCGCAGGACCGGTGGACGACCGTCGAGTA
>13.24|792617|34|CP025990|CRISPRCasFinder
AGGCACTCACGGCAGACCCACTCGGGCCGCCCGG
>13.25|792689|35|CP025990|CRISPRCasFinder
CCTCCTGGCTGGCGTGCTGGCTGGGCCACGCCGCC
>13.26|792762|37|CP025990|CRISPRCasFinder
GGCGCAACGTGCGCTGCGTGACCTCTCACAGCCTCGT

CRISPR arrays and Neighbor proteins around CP025990_13

CRISPR arrays

The CRISPR arrays of CP025990_13

>merge|CP025990|13|791846-792836|PILER-CR,CRISPRCasFinder,CRT
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACGTCGGCGAGGACGACGCCCAAAGAACCCGCGCCGCCCGGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACCTCGGTGTCTCGCGGGGACTCCCCAGCTCAGGAGCTGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACCCCGGCGAGGGCGGCGGGTGGTCGGCGGCCGTTCCCGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACCACCGCATCGCCCTCACCGACATCGACGCCCTCGCGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACCTCCGAGCCACCCCGGAGGGGGACGTCGTGCGGAGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACGAGTGGATGCTCTTGCGCAGCCTCGCTCCTGCGAGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACACCGGCCCTCACCACCCCGGCGGGTGGCCCGGCGAACGAGTTGCATCGGCCCTCCGGGGCCGGTGAGGATCGCAACTGATGACGGTCTCCCAGCTCATCGCCGCCCTGTCCCGGGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACGTCACCTATGTTCTCTATCCGGTCTTGCTGTCCTAGGGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACCTGGTCGCCGCAGGACCGGTGGACGACCGTCGAGTAGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACGAGGCACTCACGGCAGACCCACTCGGGCCGCCCGGGTTGCACCGGCCATCCGGGGCCGGTGAGGATCGCAACGCCTCCTGGCTGGCGTGCTGGCTGGGCCACGCCGCCGTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACGGGCGCAACGTGCGCTGCGTGACCTCTCACAGCCTCGTGTTGCACCGGCCCTTCGGGGCCGGCGAGGATCGCAACG

>CP025990|13|12|791846-792835|PILER-CR
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GTCGGCGAGGACGACGCCCAAAGAACCCGCGCCGCCCG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CTCGGTGTCTCGCGGGGACTCCCCAGCTCAGGAGCT
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CCCGGCGAGGGCGGCGGGTGGTCGGCGGCCGTTCCC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CACCGCATCGCCCTCACCGACATCGACGCCCTCGC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CTCCGAGCCACCCCGGAGGGGGACGTCGTGCGGA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GAGTGGATGCTCTTGCGCAGCCTCGCTCCTGCGA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	ACCGGCCCTCACCACCCCGGCGGGTGGCCCGGCGAACGA
GTTGCATCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	TGATGACGGTCTCCCAGCTCATCGCCGCCCTGTCCCGG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GTCACCTATGTTCTCTATCCGGTCTTGCTGTCCTAGG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CTGGTCGCCGCAGGACCGGTGGACGACCGTCGAGTA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GAGGCACTCACGGCAGACCCACTCGGGCCGCCCGG
GTTGCACCGGCCATCCGGGGCCGGTGAGGATCGCAAC	GCCTCCTGGCTGGCGTGCTGGCTGGGCCACGCCGCC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GGGCGCAACGTGCGCTGCGTGACCTCTCACAGCCTCGT
GTTGCACCGGCCCTTCGGGGCCGGCGAGGATCGCAAC

>CP025990|13|12|791846-792836|CRISPRCasFinder
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACG	TCGGCGAGGACGACGCCCAAAGAACCCGCGCCGCCCG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACC	TCGGTGTCTCGCGGGGACTCCCCAGCTCAGGAGCT
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACC	CCGGCGAGGGCGGCGGGTGGTCGGCGGCCGTTCCC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACC	ACCGCATCGCCCTCACCGACATCGACGCCCTCGC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACC	TCCGAGCCACCCCGGAGGGGGACGTCGTGCGGA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACG	AGTGGATGCTCTTGCGCAGCCTCGCTCCTGCGA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACA	CCGGCCCTCACCACCCCGGCGGGTGGCCCGGCGAACGA
GTTGCATCGGCCCTCCGGGGCCGGTGAGGATCGCAACT	GATGACGGTCTCCCAGCTCATCGCCGCCCTGTCCCGG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACG	TCACCTATGTTCTCTATCCGGTCTTGCTGTCCTAGG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACC	TGGTCGCCGCAGGACCGGTGGACGACCGTCGAGTA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACG	AGGCACTCACGGCAGACCCACTCGGGCCGCCCGG
GTTGCACCGGCCATCCGGGGCCGGTGAGGATCGCAACG	CCTCCTGGCTGGCGTGCTGGCTGGGCCACGCCGCC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAACG	GGCGCAACGTGCGCTGCGTGACCTCTCACAGCCTCGT
GTTGCACCGGCCCTTCGGGGCCGGCGAGGATCGCAACG

>CP025990|13|12|791846-792835|CRT
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GTCGGCGAGGACGACGCCCAAAGAACCCGCGCCGCCCG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CTCGGTGTCTCGCGGGGACTCCCCAGCTCAGGAGCT
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CCCGGCGAGGGCGGCGGGTGGTCGGCGGCCGTTCCC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CACCGCATCGCCCTCACCGACATCGACGCCCTCGC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CTCCGAGCCACCCCGGAGGGGGACGTCGTGCGGA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GAGTGGATGCTCTTGCGCAGCCTCGCTCCTGCGA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	ACCGGCCCTCACCACCCCGGCGGGTGGCCCGGCGAACGA
GTTGCATCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	TGATGACGGTCTCCCAGCTCATCGCCGCCCTGTCCCGG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GTCACCTATGTTCTCTATCCGGTCTTGCTGTCCTAGG
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	CTGGTCGCCGCAGGACCGGTGGACGACCGTCGAGTA
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GAGGCACTCACGGCAGACCCACTCGGGCCGCCCGG
GTTGCACCGGCCATCCGGGGCCGGTGAGGATCGCAAC	GCCTCCTGGCTGGCGTGCTGGCTGGGCCACGCCGCC
GTTGCACCGGCCCTCCGGGGCCGGTGAGGATCGCAAC	GGGCGCAACGTGCGCTGCGTGACCTCTCACAGCCTCGT
GTTGCACCGGCCCTTCGGGGCCGGCGAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81416.1|784802_786104_+|hypothetical-protein	unknown	unknown	gnl|CDD|187643
CP025990.1|AUS77495.1|800335_801334_+|DNA-binding-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP025990.1|AUS77483.1|780743_781580_+|thioesterase	unknown	unknown	gnl|CDD|225749
CP025990.1|AUS77490.1|793319_794063_-|peptidase-E	unknown	unknown	gnl|CDD|153240
CP025990.1|AUS77486.1|786000_786633_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380058
CP025990.1|AUS77493.1|797205_798663_+|beta-xylosidase	unknown	unknown	gnl|CDD|350143
CP025990.1|AUS77489.1|792855_793275_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77484.1|782300_782990_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
CP025990.1|AUS77482.1|780348_780570_+|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
CP025990.1|AUS77492.1|795589_796738_-|sugar-kinase	unknown	unknown	gnl|CDD|224851
CP025990.1|AUS77487.1|786688_789484_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77481.1|779255_780137_+|hypothetical-protein	unknown	unknown	gnl|CDD|276938
CP025990.1|AUS81417.1|803951_804755_+|nucleotidyltransferase	unknown	unknown	gnl|CDD|376187
CP025990.1|AUS77497.1|802929_803673_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
CP025990.1|AUS77491.1|794461_794977_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|274679
CP025990.1|AUS77480.1|775857_778926_+|hypothetical-protein	unknown	unknown	gnl|CDD|276938
CP025990.1|AUS77488.1|789480_791253_-|HSP90-family-protein	unknown	unknown	gnl|CDD|237603
CP025990.1|AUS77494.1|798853_800272_-|FAD-linked-oxidoreductase	unknown	unknown	gnl|CDD|223354
CP025990.1|AUS77496.1|801448_801910_-|DUF1348-domain-containing-protein	unknown	unknown	gnl|CDD|377770
CP025990.1|AUS77485.1|783581_784949_-|F420H(2):quinone-oxidoreductase	unknown	unknown	gnl|CDD|109787

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77495.1|800335_801334_+|DNA-binding-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	4.4e-55	182.1	0.0
CP025990.1|AUS77484.1|782300_782990_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	1.4e-16	56.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81416.1|784802_786104_+|hypothetical-protein	gnl|CDD|187643	cd08939, KDSR-like_SDR_c, 3-ketodihydrosphingosine reductase (KDSR) and related proteins, classical (c) SDR. These proteins include members identified as KDSR, ribitol type dehydrogenase, and others. The group shows strong conservation of the active site tetrad and glycine rich NAD-binding motif of the classical SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.85738e-74
CP025990.1|AUS77483.1|780743_781580_+|thioesterase	gnl|CDD|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	5.16476e-64
CP025990.1|AUS77490.1|793319_794063_-|peptidase-E	gnl|CDD|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.68953e-47
CP025990.1|AUS77486.1|786000_786633_+|TetR-family-transcriptional-regulator	gnl|CDD|380058	pfam17928, TetR_C_22, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present the TetR Transcriptional Repressor present in sco1712 proteins from Streptomyces coelicolo which act as a regulator of antibiotic production.	2.72719e-18
CP025990.1|AUS77493.1|797205_798663_+|beta-xylosidase	gnl|CDD|350143	cd18822, GH43_CtGH43-like, Glycosyl hydrolase family 43 protein such as Clostridium thermocellum exo-beta-1,3-galactanase (Ct1,3Gal43A or CtGH43). This glycosyl hydrolase family 43 (GH43) subgroup includes characterized enzymes with exo-beta-1,3-galactanase (EC 3.2.1.145, also known as galactan 1,3-beta-galactosidase) activity such as Clostridium thermocellum exo-beta-1,3-galactanase (Ct1,3Gal43A or CtGH43), Streptomyces avermitilis MA-4680 = NBRC 14893 (Sa1,3Gal43A;SAV2109) (1,3Gal43A), and Ruminiclostridium thermocellum ATCC 27405 (Ct1,3Gal43A;CtGH43;Cthe_0661) (1,3Gal43A). It belongs to the GH43_CtGH43 subgroup of the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43_CtGH43 includes proteins such as Clostridium thermocellum exo-beta-1,3-galactanase (Ct1,3Gal43A or CtGH43) which is comprised of the GH43 domain, a CBM13 domain, and a dockerin domain, exhibits an unusual ability to hydrolyze beta-1,3-galactan in the presence of a beta-1,6 linked branch, and is missing an essential acidic residue suggesting a mechanism by which it bypasses beta-1,6 linked branches in the substrate. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	5.08761e-158
CP025990.1|AUS77481.1|779255_780137_+|hypothetical-protein	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	7.03179e-42
CP025990.1|AUS77484.1|782300_782990_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.23205e-19
CP025990.1|AUS77482.1|780348_780570_+|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	2.75347e-17
CP025990.1|AUS77492.1|795589_796738_-|sugar-kinase	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	5.12178e-51
CP025990.1|AUS77495.1|800335_801334_+|DNA-binding-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	8.83046e-51
CP025990.1|AUS81417.1|803951_804755_+|nucleotidyltransferase	gnl|CDD|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	6.10976e-05
CP025990.1|AUS77497.1|802929_803673_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.55466e-14
CP025990.1|AUS77491.1|794461_794977_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.25959e-12
CP025990.1|AUS77480.1|775857_778926_+|hypothetical-protein	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	1.16324e-37
CP025990.1|AUS77488.1|789480_791253_-|HSP90-family-protein	gnl|CDD|237603	PRK14083, PRK14083, HSP90 family protein; Provisional.	0
CP025990.1|AUS77494.1|798853_800272_-|FAD-linked-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	3.57167e-27
CP025990.1|AUS77496.1|801448_801910_-|DUF1348-domain-containing-protein	gnl|CDD|377770	pfam07080, DUF1348, Protein of unknown function (DUF1348). This family consists of several highly conserved hypothetical proteins of around 150 residues in length. The function of this family is unknown.	1.41092e-86
CP025990.1|AUS77485.1|783581_784949_-|F420H(2):quinone-oxidoreductase	gnl|CDD|109787	pfam00743, FMO-like, Flavin-binding monooxygenase-like. This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.	3.82182e-46

Protein sequences

>CP025990.1|AUS77488.1|789480_791253_-|HSP90-family-protein
MNQKFQVDLRGVVDLLSHHLYSSPRVYLRELLQNAVDAVTARRVGNPDAPAAIGIELTDRALTISDTGVGLTESQVHELLATIGRSSKRDELGFARHEFLGQFGIGLLSAFLVADEVRVVTRSVSGGAAVEWLGRSDGTYAIGPAERDEPGTTASLRARRGAEQWFEPETVRDLCRLYGSLLPFRVTVAGEAVSGDGPPWRSDDRTPGERDADLLGYAQDTFGFTPFDVIDLAVPEAGLTGVAYVLPFPANPAERAGHRVYLKRMLLTESGDGLLPDWAFFARCVVDAEGLRPTASREALYDDGLLEATREALGARLRGWMTGLARTQPARLARFLEIHHLGVKALALHDDEMLRLVERWMPMETNVGRMTLADFRARHGTVRYTTTAEDFRQLAAVAAAQGLAVVNGGYTYDSEIIDRLPVVDADAVVVRLDPTDLVTRFEPVDPAEELAARPFVTAAQGVLDGLGCELVLRSFDPVNLPVLYLVDRSAAFQSELRSTRQQVDELWAGVLSAFEKPREDRPRLVLNHRNDLVRRVCASRDPEAVRLAVESLYGQALLLGYHPIRPADAALLNRSFLGLLERAIPSEDQQ
>CP025990.1|AUS77487.1|786688_789484_-|hypothetical-protein
MSHSEQEVEEMLRAAWRLPYGASQVAAAEEVVRRSDAVGRPGLRYASRILAVAAYQYGGEPAKMVVPFSWCLAAYDRGESDSRFDHQLFWYFKGVIGALTSFPEVSLDRTRAVLADMERRYRLAGHGVGPVHQRRARVHRHLGDLDAAEEEYRLWCASPRSAMSDCAGCEPSEKVYHLEDTGRYEEAVALAAPVLDGELACTEQPHGILTALLRPYLRVGALDDAADAHRRAYRAVQHDRSELALVAEHIRFCALSGNEVRGLELVERHLGWLDEPPSPMTEMEFAAAASRTLDLIVARGHGDDPVRRPGFREREATTVPVARLRDELADRALAVAARFDERNGTSHQSESVRGQLVEEPLVDHLPLSGLVRRGRSGQAPATAPTAPGEPPTAEVLPERPEALAELAEREMWFENDGRAASAWERFDELCPHPEPALLARRLVAHGFRLADGDVELAQETWRRAMTLFARVGDLVRENETRTRLGVLLCQGGRSEEGLAEINRGLLALDGDGHRGEALRARCRLAAAYHLSDRTDDAVELLAEAVERAERFGDRVVLAGVVAQHARFASQAGLDARTRLLPLWERALEELEAFPPSTLLRRVQFGLASLRANLGELPGAYGLFAEAARTDESALRFAALHRRAQVALNLGRSLEAQEQLTDLVVDLEEDGQAERAAYVRLDLADACLRIELPDEAAEATEEALPALERLGDVDELYRGRFLLAQSYRALGHVEQALALFDELVEYCEREENPAGVAQMHGHVADVLDEQDRDAEAAERYLRAAEACRRAERRVEELENRRKAALSWHWAGEGERAWEVLSGADELAAELPAGDPAVGWQRARLSYDAARILAALGRLDDGLPRASAAAAGFRALDGRVEAAIADVLRGRMLIDLDRRDEAEVVLTHALDELPEGADNYRERVAELLAELRG
>CP025990.1|AUS77486.1|786000_786633_+|TetR-family-transcriptional-regulator
MSTAIPGYRRRPAQARTQERARRILAAAEELLVGEGYAAVTTSRVAAVAGIPVSSLYHLFRDRDSIIDALVAGYLDRFLDITDDISSAVEHHTVGLDQVVSELIDGYASLYRTEPGYRVLWLGGHLDGRLAAKDRDNSSRVAERLRTVLAEQPEAAHRPELVALACRVGVEIGDHLLRLAFQENPDGDPAILEQAKIAVTAYVRQALTRR
>CP025990.1|AUS81416.1|784802_786104_+|hypothetical-protein
MSVDEVEGNGPTPERGGERQTGGSGADDEIPVRCRRGTTGTRRPFPGGHHQPREESGTRIEFELYSQDQHAVKSLPEVRAMPVTPEKPSRHPHPVPATTARHWPPRRHPSPDFWAGRHAVVTGGSSGIGLALVDRLLHLGARVSAVALDDEHLDRLTRRATTTPRLVTRALDVTDLGATRDTLAGLAEQHGPCHSLFTCAGITEPGYFHRLSDDTFRSIMEVNYFGTLHSVRAVVPAMTAAGHGTLTCVVSVAGILGVFGYGAYSPSKFAVRGLTEVLRQELRPAGVRVSAVYPPDVDTPMLAQETPLKPPELRALSGTIRPLSASRVAEAILAGTQRGHPVIIPDWRTRGLRWVAGAAPGVANAIMDRIITGASRPGGGDPRNPGPTPDRQDGKARAAREHSDPRLPTSTSAGAHPGTSTPHPRRGGGTAGR
>CP025990.1|AUS77485.1|783581_784949_-|F420H(2):quinone-oxidoreductase
MTTRKRPSGSGGPASTSDRYLVIGAGPAGLALAAAFRRRSISFDLVDRHHAIGGLWDRENPGTPLYDSAHFISSRTMSAFAGFPMPARYPDYPGHRLILDYLREFAAHHDVHEHFTGGRAVTSARPEPSGGWAVSFSDGRSHRYAGLAVATGRQWTPRRPEWPGAFDGELIHARDYDGPGRLRGRRVLVVGGGNSGVDIACDAATAAVETRLSLRRGYHVIPKYVLGRPADVFAAQSPPLPAWLRQAVMRRLLRLLAGRPEDYGLPAPDHRIFESHPILNDRILHHLGHGDVTAVPDVVALEGPEIRFTDDSTWRPDLVIQATGYRVDFPFLPPGLVGAGAGTPDLYLHVLDRRRPDLFFLGLFETDAGAFPLLSRQADLVASAVLTHRVGGPAARLLAVRKQLRPNLSGGVRHLASPRHRAYADQRVYRRELERAHRELEALRAGGDPSRWRDH
>CP025990.1|AUS77484.1|782300_782990_-|CRISPR-associated-endoribonuclease-Cas6
MRIRVDVDTKAETMHWADVFGPARAVAYTLLRSQNGELARSLHDEGWRGDPMRPFGLTCPQFRGAPRRRGVYTTSDRGAVWFGSPMPEIAGPMAAALHRHDSLRWGRTVLRVREVRVETAEPTAGGEVELTTATPVLVKYDNQFIEPTHPAFLGRLAHNLRHKADVLGLPAPQDLVLVDSGPRRRFLVQGAPRIGAVIRVRLSADPRFVEAIRSWGLGLGNNQGFGWIR
>CP025990.1|AUS77483.1|780743_781580_+|thioesterase
MTVGEVRRSGLPPLTAVQEGMPTVTTSTTGTESPWFRRFHRTAVNPRARLVCFHSAGGNANQFRSWPGLLPLDLDVLAVQPPGRQDRIGEPVVDRMDDLVSLVVAELLPLTDLPLVLFGHSMGAAVAHEVAARLEDEHDVRVPLLLVSGRAGPGRTRPRGLAYADDETLLADVSRLSQLDRALFADPDLREVVLPSIRGDYRLVETYRAPVGRTVEAPIVAYTGAADPVVRVEDVREWATATSSRFEMRVFDGGHSYLVPQEAALVADVRVRIDRALG
>CP025990.1|AUS77482.1|780348_780570_+|MbtH-family-protein
MTKGTKGTTGAEATHHRFLVLGNETGQYSVRPAFAEVPSGWTVAFGADTRRNCLDFLVSRCPVAPGRGSFRAG
>CP025990.1|AUS77481.1|779255_780137_+|hypothetical-protein
MPRACPTEAGLRFGILGSLEVEDDACDVRTPGASKPRVLLAHLLTNADRVVSVERLIAQMWRRQPPRTARTALHVYVSKLRRLLGGETTTPDRSMLVTQPPGYLLRLGGAGLDARAFDTLLATARTRANQGRLCEASQLITDALGLWRGPALADVRSAGGDLENEARRLDEARIAAYERRVELDLRLDRHADLVGELYAATSDHPMRESLHEYLMVALHRSGRPGEALEVYRAIHRSLQDTLGLEPGPRLQRLQRTVLTRGAEDLEYPGRWAGSGRGLAGGTRPRPKLSVRSA
>CP025990.1|AUS77480.1|775857_778926_+|hypothetical-protein
MNVLESRNPARASPIRTGCVRGRQARPFGGILRLDVLGPLSLFGDDGQQIVVPRGRAATVLAFLTARRGQPARRDLLVDVLWGERPPRTNAASVHNYVSTVRALLNRATESGADRLLLTPQGYRLVLHPSECDLLEFEGLVSAGRDAARRGEPARAARQLRRALDLWRGEPFPQLASSPRSWSEPRRLHELRQSVHEDCLEAELSLRRPAELVPELRQLVEDEPLSERVRALLMRALVLAGETASALAVFQEARETLVNALGIEPGRELRELHGSILRDDMPRTPPPPGGDAEGTTADPGSDETGPDPCETDPWTPPRQLPRDLPDFVGRDEVLAQILAHAASTRSVPVLVVTGGPGTGKTALAVHAAHHLVPRFPDGQLYLNLGGGSEHPVTPEDALAALLRNLGVTDACVPTGLEHRAAAYRSRLAGRRVLVVLDDAADVDQITPLLPGTAGSAVLVTGRRRLPALPSDLSTVLEPFTPEESLRFLARLLGAQRVEDEPEAAARLVELCGGLPLGIRIMLSRLETRRHWSLASLVGRMRDERRVLDGFDAGHLSVRASFTLSYSGLGEAERALFRRFPLTPARELACWALAALAGTRNPDEAIDHLLLAHLVEPADGPYERYRVHDLVRSFAAERGAEADGLVGEPTSEARAAVRRLFDTAHALIGAAHRRLPTPGGWPTPCGSPPASPPPVPVPPGLAEDAMSWLTEEAPTLVPTLVQGCELGWAASSLDAVERLAPFLAFRHRTDETRRLYRAVASGLADDRRLLARAHFGLAQSEVMAGRLDSASMLLDESAWLLADAGDHDALAHTLVLASFCRTHHQEFDVAERLAKRALRVAETTRDRHALVRSLRQWGNVRLKRGDDRAAVHLLDHALTLVEGHDEPDLEAMVLNTLANALIGLGELDRADHLCDRAVSLLDVLGQPVGRAYVRVAQVVIRAERGDHLESLAIAQDLLTTFRQFGDQRGEAYVRHRMALAELALGRSARAVPLLRAASSLYQALHMPTKAHEVRSTLDSLMPR
>CP025990.1|AUS77489.1|792855_793275_+|hypothetical-protein
MISYALAGQADASARVLDEAMRLLSQPSRDDEVRLGQRSVVGDDLYAVYQTTCDIYLGLGTDVIDALQPRLDGLARSSPRTAMISRAKLAHAYANAGQPADAVRLAWETLDAHDQVGSHSALTEVRCASGRFVRTCAGR
>CP025990.1|AUS77490.1|793319_794063_-|peptidase-E
MAADAPTILATSMGFNRARDPWRPGPVFSYAFDLAGGPPRPRLCFVSTGTGDRQASIDAFYAAFADTEVRTSHLALFEQPNVPDVAAHLHEQDVVWVDRGSVVNLLAVWHAHDLPAILADCWQAGVVLAGESAGSLCWHTWTVTDSYGGVRGSGEGLGLLPHANAVHYGEGERRAAFHHLLATEGAAGGLVGYATDTGAGLHYEHDRLVAAIADRPNAGVYRVTRSSDGEVREEPLDALRLKRGKGA
>CP025990.1|AUS77491.1|794461_794977_+|pyridoxamine-5'-phosphate-oxidase
MAIDEPVAELDPRFSAPDALPTSWLRMEKALRGAETYWLSSVRDDGRPHVSTLLAVWLDGAAYFCTGEDEQKARNIQRSPLCALTTGSNLLNEGLDVVVEGTAEQISEESVLREIADSYLDKYGEAWRFEVRDGRFHGTGGGGNVAVVYRIRPAKILAFDKGGSSQTRWRF
>CP025990.1|AUS77492.1|795589_796738_-|sugar-kinase
MFRLVLTDGPVRRGELVRRTGLSQPSITKITRAFLDRGYLAEVSPGHGRNGVGGRDVRIGRPSVPLDVRADREFVVGVKVTANELIGVVTDLRAHVRHAARNHLSGHDVADVVGSVAGLVDELRRLEPRFRVRTHALGVSVAGAVDRDRGIARYEPFHGWRDLRLADLLSAETGLPTVVDNDVRALTEAENWFGVGARADSFLLVTVGAGVTGGLVVDGRVRTGAFGVAGELGHVPVDPRGPRCYCGATGCLEAVASEPAIVRRAAELLGEPDLALPDLVRRAQGGDARVRGVFEEAGRAVGRAAAGVVNLLGPEVVVVSADHQAGLALLEPHLRAALHEASYGAAGRAEVVVRLAPFEEWARGAAAVAIARRIGDFTSPPG
>CP025990.1|AUS77493.1|797205_798663_+|beta-xylosidase
MSRTRWTRRRPGAVLAAVVGTVALLMTGVLTGTASAEPVRIPNATQFTDTDGNPLHAHGGGVLKVGDYYYWFGENRNPDFTFRHVSAYRSTDLRNWEFRNHVLTQDSDPELAVANIERPKVIYNESTGQFVMWMHKENGRDYGEARAAVAVSDTVDGDYEWRGSFRPFDEHMSRDITAFVDGDGTGYMISSARENYDLHVYRLTPDYTQVEELVHVLWPGGHREAPAMFERDGVYFLVTSGATGWNPNQQKYATAECVECPWTEPTNLGNSTAFGSQTAFVLPVEGSETTSYLYMGDRWGPAQGGTPNDSEYVWLPLEFPTPTSLTMDWTPELEIDTATGRISGLDGGQARPVVARHSSKCLDVADESTAEGHRVIQWECTGGNNQRWVSRDVGGGHVELVAWHSGRCLTVEGGSTSDGGAVTQRACTGEPHQQWRAEDAGAGHVRYVARHSGLCLDVADESTANNATVHQWSCGTGPHQQWSRG
>CP025990.1|AUS77494.1|798853_800272_-|FAD-linked-oxidoreductase
MTTSTSAITPVVATLRAEVAGPVLLPEDPGFATATVGFQTYGPHRPDVAVLAATTADVRAAVRVAADHDLPVAVLNSGHGVPPRYTGGLLVVTRDLAGVRVDPGRRVAWIEAGAPWSAVIEAAGAHGLAPLSGSTPHVGAVGYTLGGGLGLLARRFGYAADHVREIELVTADGTTRSVTARTHPDLFWASRGGGGNFGVVTGMEVDLFPVPTLYGGGLFYDAPLVGEALRAWRDWTSAAPEEITTSVALVPFPDVDGVPDPLRGRHVLHVRIAATLDVATGDEVIAPLRAVGPRLLDAVGELPYTDSATICSDPTEPMGYQTTNLFLDGLPDQALSGVLDRVGPGAPSPQVLEIRHLGGALRRPPAEANCVSHRDAEYLLGLTRRTPPDATPEQAAALRAPHAEVRAALRPWSTGASYLNFLDGDGADTERVRSAYTPENYRRLADTKARWDPRNLFRHNRNVPPTAPTSPN
>CP025990.1|AUS77495.1|800335_801334_+|DNA-binding-transcriptional-regulator
MNASLPARLLSLLSLLQSRREWSGAELARRLEVTDRTVRRDVGRLRALGYPVRGTTGTAGGYRMVAGRDLPPLLLDDEEAVAVATALLTAAGGTVTGIEDTSVRALAKLEQVLPARLRHRAAAVSRATVPLVRPAPNQVCPEVLSVLAVACRDHEVVTCSYRDRDGVVTERRVEPHHLVTGHQLWYLIAHDLRRGGWRTFRVDRISEVAPTGRRFQRGEVPGGDPAEYPRGVLLSTPFPHRAELWVAASATRVSRVLTDPLPGRVRDIEDGGCVVALGSDTVDGLLREVLAVVALGEPVTMTASDLLRERLRALSARLSEVADGGPASDGAG
>CP025990.1|AUS77496.1|801448_801910_-|DUF1348-domain-containing-protein
MPEDRPPYPPFTQETALLKVQAAEDAWNTRDPHRVATAYTPDSVWRNRDTVLRGRAEIIDFLTGKWERELDYALRKSLWTWRGNRIAVRFQYECRDRTGQWWRCYGNELWEFDDRGLMSRREASINDVAISDAQRRIHGPRLPEEHGTEIPLW
>CP025990.1|AUS77497.1|802929_803673_+|class-I-SAM-dependent-methyltransferase
MRQEEIWDAETAQRYDTPGRGRFAREVLEPTVDRLAALAGDGEALEFAIGTGRVAVPLAERGVRVTGIDLSRPMVERLRTKVDDRAVPVVIGDMATATAPGEYSLVYLVYNTISNLLTQAEQVSCFRNAARHLVPGGRFVIELEVPELRRLPPGQEALVYHAEPGYVGLDTYDTVRQHLVSHHFTFGEGRQARLARSPHRYVWPAELDLMGQLAGFDLENRWADWSGAEFTSDSRSHVSVYRLPPAP
>CP025990.1|AUS81417.1|803951_804755_+|nucleotidyltransferase
MDERGVDGTGAIVREGALDRVGAAFTPVVEATRARLAATFDADRLHSAYLYGSIPRGTAVPGTSDLDVLVALRAEPSATDRAEVRTIESELDDAFPEIDGAGILLSSMTSLLSDGERYDGGFFVACLCTPLLGQDLAELLPRYRPDSVLARETNGDLGSLLPRWRDRNAAATTDAERRSLVRGVTRRVVRTGFTLVMPRWGGWTSDLTRSADLFARYYPDQAERMRAVAEAASAPTANTDVLPMVLDDLGPWLAEEYAAVHGVPGPR

Crispr_ID: CP025990_14

• CRISPR_ID: CP025990_14
• CRISPR_location: 1142119-1142806
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers
• Cas_protein_info: WYL

Consensus repeat of CP025990_14

Consensus_repeat	Method
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	PILER-CR
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CRISPRCasFinder
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CRT

spacers of CP025990_14

>14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCCTCCAGCAGCGCGACGACGTCGACGACCTTCGC
>14.2|1142214|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCGAGAGGGAGGCCAAGGACGCCGAGAACGCCGCGA
>14.3|1142280|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
ATGTTGAACTTGGGGCGCGGCTTGTCCAGGGCCGA
>14.4|1142345|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCCACAGGAGAACGTGCCCCAGCGCGGAGTCGGGGG
>14.5|1142411|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACGAGCACGGCCACCTCAACGTGACCCGGGGGGGACC
>14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACCGGGACACCGGGGACGCCTGCGACGCCGACGGG
>14.7|1142543|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCGTTGGTGAACGACCAGCTCCGGAGCGTCTCCGGG
>14.8|1142609|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGCTCGTACCCGGCGATCCGTTCGACCGGGTACCCG
>14.9|1142675|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCGCAACCGAGATCGATTGGTGCCGGCCGCTTGCCG
>14.10|1142741|36|CP025990|CRISPRCasFinder,CRT
GTGCCGGCCAGGCGCAGCAGCGCCGGCAGGTCCCAT

CRISPR arrays and Neighbor proteins around CP025990_14

CRISPR arrays

The CRISPR arrays of CP025990_14

>merge|CP025990|14|1142119-1142806|PILER-CR,CRISPRCasFinder,CRT
GTCCTCATCGCCCCTAAGAGGGGTCACAACTCCTCCAGCAGCGCGACGACGTCGACGACCTTCGCGTCCTCATCGCCCCTAAGAGGGGTCACAACCCGAGAGGGAGGCCAAGGACGCCGAGAACGCCGCGAGTCCTCATCGCCCCTAAGAGGGGTCACAACATGTTGAACTTGGGGCGCGGCTTGTCCAGGGCCGAGTCCTCATCGCCCCTAAGAGGGGTCACAACTCCACAGGAGAACGTGCCCCAGCGCGGAGTCGGGGGGTCCTCATCGCCCCTAAGAGGGGTCACAACACGAGCACGGCCACCTCAACGTGACCCGGGGGGGACCGTCCTCATCGCCCCTAAGAGGGGTCACAACACCGGGACACCGGGGACGCCTGCGACGCCGACGGGGTCCTCATCGCCCCTAAGAGGGGTCACAACTCGTTGGTGAACGACCAGCTCCGGAGCGTCTCCGGGGTCCTCATCGCCCCTAAGAGGGGTCACAACGGCTCGTACCCGGCGATCCGTTCGACCGGGTACCCGGTCCTCATCGCCCCTAAGAGGGGTCACAACCCGCAACCGAGATCGATTGGTGCCGGCCGCTTGCCGGTCCTCATCGCCCCTAAAAGGGGTCACAACGTGCCGGCCAGGCGCAGCAGCGCCGGCAGGTCCCATGTCCTCATCGCCCCTAAGAAGGGTCACGAC

>CP025990|14|13|1142119-1142740|PILER-CR
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCCTCCAGCAGCGCGACGACGTCGACGACCTTCGC
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CCGAGAGGGAGGCCAAGGACGCCGAGAACGCCGCGA
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ATGTTGAACTTGGGGCGCGGCTTGTCCAGGGCCGA
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCCACAGGAGAACGTGCCCCAGCGCGGAGTCGGGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ACGAGCACGGCCACCTCAACGTGACCCGGGGGGGACC
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ACCGGGACACCGGGGACGCCTGCGACGCCGACGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCGTTGGTGAACGACCAGCTCCGGAGCGTCTCCGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	GGCTCGTACCCGGCGATCCGTTCGACCGGGTACCCG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CCGCAACCGAGATCGATTGGTGCCGGCCGCTTGCCG
GTCCTCATCGCCCCTAAAAGGGGTCACAAC

>CP025990|14|13|1142119-1142806|CRISPRCasFinder
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCCTCCAGCAGCGCGACGACGTCGACGACCTTCGC
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CCGAGAGGGAGGCCAAGGACGCCGAGAACGCCGCGA
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ATGTTGAACTTGGGGCGCGGCTTGTCCAGGGCCGA
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCCACAGGAGAACGTGCCCCAGCGCGGAGTCGGGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ACGAGCACGGCCACCTCAACGTGACCCGGGGGGGACC
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ACCGGGACACCGGGGACGCCTGCGACGCCGACGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCGTTGGTGAACGACCAGCTCCGGAGCGTCTCCGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	GGCTCGTACCCGGCGATCCGTTCGACCGGGTACCCG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CCGCAACCGAGATCGATTGGTGCCGGCCGCTTGCCG
GTCCTCATCGCCCCTAAAAGGGGTCACAAC	GTGCCGGCCAGGCGCAGCAGCGCCGGCAGGTCCCAT
GTCCTCATCGCCCCTAAGAAGGGTCACGAC

>CP025990|14|13|1142119-1142806|CRT
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCCTCCAGCAGCGCGACGACGTCGACGACCTTCGC
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CCGAGAGGGAGGCCAAGGACGCCGAGAACGCCGCGA
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ATGTTGAACTTGGGGCGCGGCTTGTCCAGGGCCGA
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCCACAGGAGAACGTGCCCCAGCGCGGAGTCGGGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ACGAGCACGGCCACCTCAACGTGACCCGGGGGGGACC
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	ACCGGGACACCGGGGACGCCTGCGACGCCGACGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	TCGTTGGTGAACGACCAGCTCCGGAGCGTCTCCGGG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	GGCTCGTACCCGGCGATCCGTTCGACCGGGTACCCG
GTCCTCATCGCCCCTAAGAGGGGTCACAAC	CCGCAACCGAGATCGATTGGTGCCGGCCGCTTGCCG
GTCCTCATCGCCCCTAAAAGGGGTCACAAC	GTGCCGGCCAGGCGCAGCAGCGCCGGCAGGTCCCAT
GTCCTCATCGCCCCTAAGAAGGGTCACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77733.1|1134356_1136468_+|xanthine-dehydrogenase	unknown	unknown	gnl|CDD|224446
CP025990.1|AUS77743.1|1149461_1150322_-|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	unknown	unknown	gnl|CDD|223268
CP025990.1|AUS81467.1|1142825_1143353_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77741.1|1148039_1148489_+|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS81469.1|1146058_1146805_-|ABC-transporter	unknown	unknown	gnl|CDD|366444
CP025990.1|AUS77730.1|1131692_1132670_+|DNA-binding-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP025990.1|AUS81468.1|1144705_1146052_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
CP025990.1|AUS77729.1|1131269_1131617_-|hypothetical-protein	unknown	unknown	gnl|CDD|378915
CP025990.1|AUS77732.1|1133367_1134360_+|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl|CDD|224238
CP025990.1|AUS77734.1|1136707_1137664_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
CP025990.1|AUS77738.1|1140817_1141789_+|pseudouridylate-synthase	unknown	unknown	gnl|CDD|211332
CP025990.1|AUS77745.1|1151888_1152680_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
CP025990.1|AUS77731.1|1132855_1133371_+|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|236910
CP025990.1|AUS77736.1|1139551_1140118_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
CP025990.1|AUS77744.1|1150318_1150939_-|formimidoyltetrahydrofolate-cyclodeaminase	unknown	unknown	gnl|CDD|377428
CP025990.1|AUS77742.1|1148524_1149394_+|hypothetical-protein	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77740.1|1146822_1147758_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
CP025990.1|AUS77739.1|1144088_1144709_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
CP025990.1|AUS77737.1|1140217_1140631_+|hypothetical-protein	unknown	unknown	gnl|CDD|236307
CP025990.1|AUS77735.1|1137707_1138967_-|MFS-transporter	unknown	unknown	gnl|CDD|340951

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS77730.1|1131692_1132670_+|DNA-binding-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	2.7e-45	149.9	5.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77738.1|1140817_1141789_+|pseudouridylate-synthase	gnl|CDD|211332	cd02558, PSRA_1, Pseudouridine synthase, a subgroup of the RluA family. This group is comprised of bacterial proteins assigned to the RluA family of pseudouridine synthases. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. The RluA family is comprised of proteins related to Escherichia coli RluA.	3.92245e-131
CP025990.1|AUS77733.1|1134356_1136468_+|xanthine-dehydrogenase	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	0
CP025990.1|AUS77743.1|1149461_1150322_-|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	gnl|CDD|223268	COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism].	2.18356e-104
CP025990.1|AUS77741.1|1148039_1148489_+|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	6.30487e-06
CP025990.1|AUS81469.1|1146058_1146805_-|ABC-transporter	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.95422e-11
CP025990.1|AUS77730.1|1131692_1132670_+|DNA-binding-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.71033e-37
CP025990.1|AUS81468.1|1144705_1146052_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	8.32073e-61
CP025990.1|AUS77729.1|1131269_1131617_-|hypothetical-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	4.80369e-07
CP025990.1|AUS77732.1|1133367_1134360_+|xanthine-dehydrogenase-family-protein-subunit-M	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	2.78437e-84
CP025990.1|AUS77734.1|1136707_1137664_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	1.27509e-38
CP025990.1|AUS77739.1|1144088_1144709_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.20973e-71
CP025990.1|AUS77745.1|1151888_1152680_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.85165e-26
CP025990.1|AUS77731.1|1132855_1133371_+|(2Fe-2S)-binding-protein	gnl|CDD|236910	PRK11433, PRK11433, aldehyde oxidoreductase 2Fe-2S subunit; Provisional.	1.36778e-77
CP025990.1|AUS77736.1|1139551_1140118_+|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.17728e-31
CP025990.1|AUS77744.1|1150318_1150939_-|formimidoyltetrahydrofolate-cyclodeaminase	gnl|CDD|377428	pfam04961, FTCD_C, Formiminotransferase-cyclodeaminase. Members of this family are thought to be Formiminotransferase- cyclodeaminase enzymes EC:4.3.1.4. This domain is found in the C-terminus of the bifunctional animal members of the family.	1.03648e-48
CP025990.1|AUS77742.1|1148524_1149394_+|hypothetical-protein	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.06705e-78
CP025990.1|AUS77740.1|1146822_1147758_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.03526e-96
CP025990.1|AUS77737.1|1140217_1140631_+|hypothetical-protein	gnl|CDD|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	1.73432e-15
CP025990.1|AUS77735.1|1137707_1138967_-|MFS-transporter	gnl|CDD|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.25868e-83

Protein sequences

>CP025990.1|AUS77738.1|1140817_1141789_+|pseudouridylate-synthase
MRRKARSPLPQRNGLDAARLRLPADGPWATLREHLVDRLPRVAPERIDALFREGGFVDHSGPLAPDSPFVPHAVLWFHRDLPEEVPVPFEIGIVHQDEDLLVVDKPHFLASIPRGRHILQTALVRLRDELDLPDLVPAHRLDRVTAGLLMFVVRPELRGAYQTLFRDRVVHKEYQAVAPHDPAVELPRTVRSRIVKERGVITAQEVPGAPNSETRIELVEHRDGLGRYRLLPSTGRTHQLRLHLAGLGLPILGDDFYPMLTEKPLDDFTRPLQLLAKALSFTDPVTGRPRRFESRLTLGAWDDYETWSGGRHDPRPTSSASHP
>CP025990.1|AUS77737.1|1140217_1140631_+|hypothetical-protein
MVVNRGEIALRVIRSCRELGIRTVVAHSTADDDPPATRAADACGCGTDQVPPRLNPGRATYRRTTNPLAPSTTARPGRQHPEATPADRRRACALRARPHVARPPRGPRGRQLPRSVRRTSPPQALPATSPSSRIARA
>CP025990.1|AUS77736.1|1139551_1140118_+|TetR-family-transcriptional-regulator
MTTRRVDPERRDRIITAALDLIAEEGVAGTSHRKVARAADVPLGSMTYHFTGMDELLREAFSRFAGAVSARMDHRLGRARDREEAKAAIADIIHHHIFDTARNLVLTHELYTLAARKPAFRSITHDWMRRTRHALERHFDPDTARQLDSLIEGLTIQHALGTEPLERAFTVDAIERISGGSTPSPPGS
>CP025990.1|AUS77735.1|1137707_1138967_-|MFS-transporter
MAADEQGTVVPPEHRETARRRFALLVLFAIPGISLASWVTRTPAIRDQLDATTGQMGLVLFGLSIGSMTGVISAATFVRRYGTRRVAAVSMMLMIAGLAVIGLAAFLASAVVAFLGLLLFGLGMGAGEIAVNIDGAEVERLQGRPLLPTLHGTFSLGTVAGALLGIWFTAVDFPVAVHLAGVAGLCATAAVLAVRAVPAGFGQRPPAATRGVLAASRRQREVWRDSRILLIGVVALAIALAEGAANDWLPLLMVDGHGFDPTSGSLVYTGFVAAMTVGRFCGSVVVRRFGRVAVVRASASLGAVGLATVVFVDNPVVAACAVVVWGLGVSLGFPLAISAAGDGGGDATARVSAVATAGYVAFLVGPPLLGFLGDHVGLRDAMIVVLVLVVCALFAAGATRPPAEDDDGVGHASAGTRTG
>CP025990.1|AUS77734.1|1136707_1137664_-|LLM-class-flavin-dependent-oxidoreductase
MIVDDRATGVLLPRDLPAGRVLDFAREAERFGFGELWVVEDLGFRGGFAQAGAVLAATDRIRVGIGVLPVGARGVAFAAMEAATLAELFPGRVDIGVGHGMPDWMRQVGAWPASPLTLLEEYTVALRALLRGERVDVAGRHVRLDGVRLETPPAVPPPVLAGVRGPRSLAVAGRVAEGTVLAEPVSPEYARTALGSIASHGPHRLVGYNLAVVHDDGGAAVAAVRPALAPLGEPDWRPHLAPLPFADEVVALRDGCADGAEFARRLPAEWVRQLAVVGTPDQARRRVDVLHEAGVTSTVLIPVGSDPFVSLASLARVL
>CP025990.1|AUS77733.1|1134356_1136468_+|xanthine-dehydrogenase
MTGTPPPAPAESGRPRERLDGPAKVAGRAPYAYEQPVEDPLFLFPVRSTIARGRVRWVDTEEAEAVPGVVAVLTHLNAPRLASRDDLELWVLQDDEVRHHGQFVGAVIAGTPEVARHAASLVKVEYQREWHDVVLRADHPERYRPDHVNPSFDTDTSHGDVDGALADAAATVDQTYRTPVQHHVPMEPHTTVVRWPGAADLGAVAMYDSNQGVSPIRKVLAPLLDLDPEQLWIHSPHVGGAFGSKASPKAHHVLTALAARLVPGRPVKCALTRQQMFGNAGHRTPTIQRVRLGADRRGRLTAIAHDVVEHTARFKEFAEQTAVATRTMYAAEHRRTTHRLVPLDVPAPVIMRAPGEAPGMFALESAMDELAVALGMDPVELRIRNEPDADPESGLPFSTRHLARCLREGATRFGWADRPPAGQGRRDGDWLVGVGMAASTYPLFPQQGSRARIRALPDGRRQVEIAASDLGTGTWTALTQIAADALRVPAEAVDLVIGDSALPATVGAGGSSGLSIWGTTVVAAARAFRDRHGDDPPAGAEVVGELPENTAVGRYALHAFGAQFAEVRVDAVTGEIRVPRMVGVFDVGRVINPRTARSQLMGGMTMGLSMALHEESVVDPRFGHVVNGDYAGYHIPTNADVGDIDVSWLDEPDPLYNPMGSKGIGEIGIVGTAAAIANAVWHATGVRVRDVPITPDRLLGRHR
>CP025990.1|AUS77732.1|1133367_1134360_+|xanthine-dehydrogenase-family-protein-subunit-M
MIPFDYHRATDVEDAVRTATSRPDATYLAGGTNLVDHLRLGITSPSLLVDVSRLPFDDIDPLPDGGVRVGAGVRNSDLAAHPTIRRDYPMLAAALLAGASWQLRNLATTGGNLLQRTRCAYFQNPATPCNKREPGSGCSALAGWQRHHAILGASEHCVAVHPSDMAVPLAALDATVRLTGAHGDRGVPLTAFHRLPGDEPRRDTVLEHGELITAVDLPRLPPTTRSAYRKVRDRASYAFALVSVAAALTVTDGVVRDVRIALGGVAHKPWRATRAEETLRGADARPASFRAAAEAELAEAEPLPGSAFKTTMAREALVSVLTGLAEEGAR
>CP025990.1|AUS77731.1|1132855_1133371_+|(2Fe-2S)-binding-protein
MEAEIRLRVDGTTHTLRVDTRTSLLDALRDRLGNTSPKKGCDHGQCGSCTVLLDGRRITSCLALAVSHDGAEVTTADGLAPGDTLHPVQRAFLDQDAFQCGYCTPGQVCSVVGMLAEATDGRASHVTGELTGPVQLTDEEIRERLSGNLCRCGAYVNIVAAVRQTLAEEAP
>CP025990.1|AUS77730.1|1131692_1132670_+|DNA-binding-transcriptional-regulator
MRADRLVSLVLLLRQHGRLSASALARELEVSTRTVLRDVEALSTAGVPIYAERGRHGGFALLPGFRTELTGLNHDEALALLVVGSRRGAQAFGLGPALASAMRKVVDALPEGSRASAAGAVQRLLVDPETDLLERRLVAEEVVPTPVVAEVRRAVFAGSRLRIHYAAAEQPPAWRTVDPIGLVTARDQVYLLATRSGADRTYRLSRVLAAEALPEPARRPDRVDLAGVWRERGRRFRAGGQQITVLVRVDPARRAELVGTAVAVHSEDTGPDGWPRLEVSFQDARHAEWALWRLAADAEALEPQWLRTSLRDRAATLAARYATPS
>CP025990.1|AUS77729.1|1131269_1131617_-|hypothetical-protein
MATEPNDLGRYFIERGNVGDVDGLVALYEPDAVLAFPPGNVSKGHAEIREVYERFVAAAPELEPGRQHPALVSGDLALTVSTLTTGEMAVEVARRQEDGTWLWVVDQPVLLPDNG
>CP025990.1|AUS81467.1|1142825_1143353_-|hypothetical-protein
MNEVAVRALEPGGLAGATPVAELAPELREVLDEGIVRAGPALVFARRATRAHAPHAATEDLTAWECATNEIHLDDVVPVDVGCLEDGEPVISEADQVRMSRHGLGFALEVVRLVRALPEPVAVRCIVGANSTNGTFRFHRARPGESWLGPDVDGFLGDKLIVVDSGPASLGGTPW
>CP025990.1|AUS77739.1|1144088_1144709_-|DNA-binding-response-regulator
MIRLVVVDDHPIVRGGLRDTFADAEDILVVGEAGDGAEGIERAERLAADVVLMDLRMPGMDGVAATAALRERSPNTRVLILTTFDSESDVLPAIEAGATGYLLKDALPDELTRAVRAAARGEPVLAPSVTHHLMGQVRRPGRGTLTDREREVLQLVANGSSNREAATALFIGEASIKTHLQHIYDKLGVRDRASAVAEGYRRRLLT
>CP025990.1|AUS81468.1|1144705_1146052_-|two-component-sensor-histidine-kinase
MTRDAGTGERLNFAAHESAISQEAAIANRSRLAWKAEQLRVWDLLQLVSPWLLLAISTAIHFSWVLPTSGEPFWPDGPAVLGLVAISVLWVLFGHTLPIRRRTLRPTSAGIYLVGLLASCVTLMTYSDIFLVFIIAGFFHAYLLRPWPLGVLGVLATSVALNGSVMRVWAHPAPDVLAEFILIVAVQTAAIGVGILLTAHTEPEERRREELVERLEAALHENAGLHAQLVAQARESGAQDERQRLAGEIHDTLAQGLAGIITQLQAAERSARAPGEAEEHVARALRLARDSLTEARRSVRALAPQELGRAHLPDALRTLTERWSEDQGIRTQVEVTGTREPLSPAIEVSLFRVAQESLTNVAKHAEASRVGVTLSYTGTEVLLDVRDDGRGFTNGVGTGFGLTSMRQRIRGVGGHVEVQSAPGEGTSVSARVPAIAPGGTGAKGETDG
>CP025990.1|AUS81469.1|1146058_1146805_-|ABC-transporter
MVKVEGKLFLRDSATVIFGVLFPTGLLLGLGAIPALREPSPETGGLRDIDIWAPTALVFGMVMIAVQHVPAVTATYRERGILRRLSTTPAHPRGVLLAQMIVALSSVVVSAALMTFLAWAVLDIAPPERPLEFVVAFVVGYAALLGLGMVSAAVVRTSSAANQLGTLLFVALMFFGGAFLPRVVMPDVLREVGEFIPPGLQALTAAWSAEAGQITATAGGQPFWPQIAVMAGIAVTASAVAAKLFRWE
>CP025990.1|AUS77740.1|1146822_1147758_-|ABC-transporter-ATP-binding-protein
MTALEVRNLHKRYGQHVAVDDVSFTVEKGEIFGIIGPNGAGKTTTVESIAGLRTPDSGSLSVLGLDPTKDRAEVRERLGVQLQESSFPDAIKVAEALELHSSFYRNPADWRELMELLGLTEKRDTQYKALSGGQKQRLSIALALVGNPEVAILDELTTGLDPQARRDTWSLIERVRDTGVTILLVTHFMDEAERLSDRIAVINGGRVAAVDTPAGLIARSSGARQVRFRVSQPLDRSVLTDLPDVTDVEITEGRWLVTGRGQLLSSVAGALARARVVAEDLRVDQRNLDDAFVAFTGRAPESPGNSTRRVG
>CP025990.1|AUS77741.1|1148039_1148489_+|hypothetical-protein
MTPEVIVPSSPRTRGCSGSLILVPYWICWRPCTPGRMRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTDTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS77742.1|1148524_1149394_+|hypothetical-protein
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNQLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSIGRRGDSYDNAPAESVYALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEQRNRRQAMAADGRERH
>CP025990.1|AUS77743.1|1149461_1150322_-|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase
MTTVLSGKVLAAQIKKDTAERVQALTARGVQVGLAIVTATDDEASAWYVRSITKAAAAVGIAGRVEELGVTATESDIRSMLVKLGDDPGVHGIILQTPLPDGVRSERVSVAIAPEKDVDGANPESFGRLATGLRAFAPATAQAVVELLDHHGIDLHGKHAVVVGRSTVVGKPLAHLLLDRHSTVTIAHSRTHGLAEVTSRGDVVVAAVGRARLITADHIGPVAVVVDVGTNPTPEGGLVGDVDPGVTGKAAALSPVPGGVGPVTTALLLRHTVDVAERGGRAAVGS
>CP025990.1|AUS77744.1|1150318_1150939_-|formimidoyltetrahydrofolate-cyclodeaminase
MHRSAIGAFLDELAARTPTPGGGASSALHAAQAAALVGMVGRYSDGAKYAEHADTIGRIVAESDDVREAALAVAARDAAAFEAVGHAYALPRGTEPQEVERRQAIERALVASAAPPVEVVELTDRIVGLAEGLLPIGNRNVVTDIACAAEAARAAAVTARVNIEINRAGIKDEPTRTELAAQAARVQVITKRAERVTSAVLEGISK
>CP025990.1|AUS77745.1|1151888_1152680_+|FkbM-family-methyltransferase
MVMAQEDRLVAYVVPDTTSAGRTHEFLTRSQSGELDGLPSRELPNGMIVLGRNNAEIDFLHQEIFERREYLRHGVTLPRDAVVFDIGAHIGLFSLFVAQNAPDATIYAFEPIPDLRREFALNMSVNGVEAHVFECGVGAEPGTASFTFYPQLSMLSGRFGDESDERAVVEAYALRNAGEGVVGAIAELVTERLRDRHDVVCSVRTVSDIIDEHRVEQIDLLKVDAEMSEAEVLRGIRPEHWSRIRQVVAEVHDRDGRLDMVTE

Crispr_ID: CP025990_15

• CRISPR_ID: CP025990_15
• CRISPR_location: 1148002-1148090
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP025990_15

Consensus_repeat	Method
GTCGTTCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder

spacers of CP025990_15

>15.1|1148030|33|CP025990|CRISPRCasFinder
AGGGGGAGGAATGACGCCAGAGGTGATCGTGCC

CRISPR arrays and Neighbor proteins around CP025990_15

CRISPR arrays

The CRISPR arrays of CP025990_15

>merge|CP025990|15|1148002-1148090|CRISPRCasFinder
GTCGTTCCCGCGCACGCGGGGCTGTTCCAGGGGGAGGAATGACGCCAGAGGTGATCGTGCCGTCGTCCCCGCGCACGCGGGGCTGTTCC

>CP025990|15|14|1148002-1148090|CRISPRCasFinder
GTCGTTCCCGCGCACGCGGGGCTGTTCC	AGGGGGAGGAATGACGCCAGAGGTGATCGTGCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS77748.1|1158703_1159129_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81467.1|1142825_1143353_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81470.1|1157206_1157992_+|hypothetical-protein	unknown	unknown	gnl|CDD|341301
CP025990.1|AUS77743.1|1149461_1150322_-|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	unknown	unknown	gnl|CDD|223268
CP025990.1|AUS81469.1|1146058_1146805_-|ABC-transporter	unknown	unknown	gnl|CDD|366444
CP025990.1|AUS81468.1|1144705_1146052_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
CP025990.1|AUS77750.1|1161169_1161352_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS77738.1|1140817_1141789_+|pseudouridylate-synthase	unknown	unknown	gnl|CDD|211332
CP025990.1|AUS77742.1|1148524_1149394_+|hypothetical-protein	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS77739.1|1144088_1144709_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
CP025990.1|AUS77745.1|1151888_1152680_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
CP025990.1|AUS77747.1|1154131_1155436_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
CP025990.1|AUS77736.1|1139551_1140118_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
CP025990.1|AUS77744.1|1150318_1150939_-|formimidoyltetrahydrofolate-cyclodeaminase	unknown	unknown	gnl|CDD|377428
CP025990.1|AUS77734.1|1136707_1137664_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
CP025990.1|AUS77740.1|1146822_1147758_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
CP025990.1|AUS77746.1|1152676_1154005_+|hypothetical-protein	unknown	unknown	gnl|CDD|236668
CP025990.1|AUS77737.1|1140217_1140631_+|hypothetical-protein	unknown	unknown	gnl|CDD|236307
CP025990.1|AUS77749.1|1160383_1160809_-|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl|CDD|377399
CP025990.1|AUS77735.1|1137707_1138967_-|MFS-transporter	unknown	unknown	gnl|CDD|340951

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS77743.1|1149461_1150322_-|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	gnl|CDD|223268	COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism].	2.18356e-104
CP025990.1|AUS81470.1|1157206_1157992_+|hypothetical-protein	gnl|CDD|341301	cd17646, A_NRPS_AB3403-like, Peptide Synthetase. The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions.	2.35431e-48
CP025990.1|AUS77745.1|1151888_1152680_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.85165e-26
CP025990.1|AUS81469.1|1146058_1146805_-|ABC-transporter	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.95422e-11
CP025990.1|AUS81468.1|1144705_1146052_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	8.32073e-61
CP025990.1|AUS77738.1|1140817_1141789_+|pseudouridylate-synthase	gnl|CDD|211332	cd02558, PSRA_1, Pseudouridine synthase, a subgroup of the RluA family. This group is comprised of bacterial proteins assigned to the RluA family of pseudouridine synthases. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. The RluA family is comprised of proteins related to Escherichia coli RluA.	3.92245e-131
CP025990.1|AUS77742.1|1148524_1149394_+|hypothetical-protein	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.06705e-78
CP025990.1|AUS77739.1|1144088_1144709_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.20973e-71
CP025990.1|AUS77747.1|1154131_1155436_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.14601e-69
CP025990.1|AUS77736.1|1139551_1140118_+|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.17728e-31
CP025990.1|AUS77744.1|1150318_1150939_-|formimidoyltetrahydrofolate-cyclodeaminase	gnl|CDD|377428	pfam04961, FTCD_C, Formiminotransferase-cyclodeaminase. Members of this family are thought to be Formiminotransferase- cyclodeaminase enzymes EC:4.3.1.4. This domain is found in the C-terminus of the bifunctional animal members of the family.	1.03648e-48
CP025990.1|AUS77734.1|1136707_1137664_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	1.27509e-38
CP025990.1|AUS77740.1|1146822_1147758_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.03526e-96
CP025990.1|AUS77746.1|1152676_1154005_+|hypothetical-protein	gnl|CDD|236668	PRK10252, entF, enterobactin non-ribosomal peptide synthetase EntF.	3.12344e-62
CP025990.1|AUS77737.1|1140217_1140631_+|hypothetical-protein	gnl|CDD|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	1.73432e-15
CP025990.1|AUS77749.1|1160383_1160809_-|SsgA-family-sporulation/cell-division-regulator	gnl|CDD|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	5.05492e-39
CP025990.1|AUS77735.1|1137707_1138967_-|MFS-transporter	gnl|CDD|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.25868e-83

Protein sequences

>CP025990.1|AUS77740.1|1146822_1147758_-|ABC-transporter-ATP-binding-protein
MTALEVRNLHKRYGQHVAVDDVSFTVEKGEIFGIIGPNGAGKTTTVESIAGLRTPDSGSLSVLGLDPTKDRAEVRERLGVQLQESSFPDAIKVAEALELHSSFYRNPADWRELMELLGLTEKRDTQYKALSGGQKQRLSIALALVGNPEVAILDELTTGLDPQARRDTWSLIERVRDTGVTILLVTHFMDEAERLSDRIAVINGGRVAAVDTPAGLIARSSGARQVRFRVSQPLDRSVLTDLPDVTDVEITEGRWLVTGRGQLLSSVAGALARARVVAEDLRVDQRNLDDAFVAFTGRAPESPGNSTRRVG
>CP025990.1|AUS81469.1|1146058_1146805_-|ABC-transporter
MVKVEGKLFLRDSATVIFGVLFPTGLLLGLGAIPALREPSPETGGLRDIDIWAPTALVFGMVMIAVQHVPAVTATYRERGILRRLSTTPAHPRGVLLAQMIVALSSVVVSAALMTFLAWAVLDIAPPERPLEFVVAFVVGYAALLGLGMVSAAVVRTSSAANQLGTLLFVALMFFGGAFLPRVVMPDVLREVGEFIPPGLQALTAAWSAEAGQITATAGGQPFWPQIAVMAGIAVTASAVAAKLFRWE
>CP025990.1|AUS81468.1|1144705_1146052_-|two-component-sensor-histidine-kinase
MTRDAGTGERLNFAAHESAISQEAAIANRSRLAWKAEQLRVWDLLQLVSPWLLLAISTAIHFSWVLPTSGEPFWPDGPAVLGLVAISVLWVLFGHTLPIRRRTLRPTSAGIYLVGLLASCVTLMTYSDIFLVFIIAGFFHAYLLRPWPLGVLGVLATSVALNGSVMRVWAHPAPDVLAEFILIVAVQTAAIGVGILLTAHTEPEERRREELVERLEAALHENAGLHAQLVAQARESGAQDERQRLAGEIHDTLAQGLAGIITQLQAAERSARAPGEAEEHVARALRLARDSLTEARRSVRALAPQELGRAHLPDALRTLTERWSEDQGIRTQVEVTGTREPLSPAIEVSLFRVAQESLTNVAKHAEASRVGVTLSYTGTEVLLDVRDDGRGFTNGVGTGFGLTSMRQRIRGVGGHVEVQSAPGEGTSVSARVPAIAPGGTGAKGETDG
>CP025990.1|AUS77739.1|1144088_1144709_-|DNA-binding-response-regulator
MIRLVVVDDHPIVRGGLRDTFADAEDILVVGEAGDGAEGIERAERLAADVVLMDLRMPGMDGVAATAALRERSPNTRVLILTTFDSESDVLPAIEAGATGYLLKDALPDELTRAVRAAARGEPVLAPSVTHHLMGQVRRPGRGTLTDREREVLQLVANGSSNREAATALFIGEASIKTHLQHIYDKLGVRDRASAVAEGYRRRLLT
>CP025990.1|AUS81467.1|1142825_1143353_-|hypothetical-protein
MNEVAVRALEPGGLAGATPVAELAPELREVLDEGIVRAGPALVFARRATRAHAPHAATEDLTAWECATNEIHLDDVVPVDVGCLEDGEPVISEADQVRMSRHGLGFALEVVRLVRALPEPVAVRCIVGANSTNGTFRFHRARPGESWLGPDVDGFLGDKLIVVDSGPASLGGTPW
>CP025990.1|AUS77738.1|1140817_1141789_+|pseudouridylate-synthase
MRRKARSPLPQRNGLDAARLRLPADGPWATLREHLVDRLPRVAPERIDALFREGGFVDHSGPLAPDSPFVPHAVLWFHRDLPEEVPVPFEIGIVHQDEDLLVVDKPHFLASIPRGRHILQTALVRLRDELDLPDLVPAHRLDRVTAGLLMFVVRPELRGAYQTLFRDRVVHKEYQAVAPHDPAVELPRTVRSRIVKERGVITAQEVPGAPNSETRIELVEHRDGLGRYRLLPSTGRTHQLRLHLAGLGLPILGDDFYPMLTEKPLDDFTRPLQLLAKALSFTDPVTGRPRRFESRLTLGAWDDYETWSGGRHDPRPTSSASHP
>CP025990.1|AUS77737.1|1140217_1140631_+|hypothetical-protein
MVVNRGEIALRVIRSCRELGIRTVVAHSTADDDPPATRAADACGCGTDQVPPRLNPGRATYRRTTNPLAPSTTARPGRQHPEATPADRRRACALRARPHVARPPRGPRGRQLPRSVRRTSPPQALPATSPSSRIARA
>CP025990.1|AUS77736.1|1139551_1140118_+|TetR-family-transcriptional-regulator
MTTRRVDPERRDRIITAALDLIAEEGVAGTSHRKVARAADVPLGSMTYHFTGMDELLREAFSRFAGAVSARMDHRLGRARDREEAKAAIADIIHHHIFDTARNLVLTHELYTLAARKPAFRSITHDWMRRTRHALERHFDPDTARQLDSLIEGLTIQHALGTEPLERAFTVDAIERISGGSTPSPPGS
>CP025990.1|AUS77735.1|1137707_1138967_-|MFS-transporter
MAADEQGTVVPPEHRETARRRFALLVLFAIPGISLASWVTRTPAIRDQLDATTGQMGLVLFGLSIGSMTGVISAATFVRRYGTRRVAAVSMMLMIAGLAVIGLAAFLASAVVAFLGLLLFGLGMGAGEIAVNIDGAEVERLQGRPLLPTLHGTFSLGTVAGALLGIWFTAVDFPVAVHLAGVAGLCATAAVLAVRAVPAGFGQRPPAATRGVLAASRRQREVWRDSRILLIGVVALAIALAEGAANDWLPLLMVDGHGFDPTSGSLVYTGFVAAMTVGRFCGSVVVRRFGRVAVVRASASLGAVGLATVVFVDNPVVAACAVVVWGLGVSLGFPLAISAAGDGGGDATARVSAVATAGYVAFLVGPPLLGFLGDHVGLRDAMIVVLVLVVCALFAAGATRPPAEDDDGVGHASAGTRTG
>CP025990.1|AUS77734.1|1136707_1137664_-|LLM-class-flavin-dependent-oxidoreductase
MIVDDRATGVLLPRDLPAGRVLDFAREAERFGFGELWVVEDLGFRGGFAQAGAVLAATDRIRVGIGVLPVGARGVAFAAMEAATLAELFPGRVDIGVGHGMPDWMRQVGAWPASPLTLLEEYTVALRALLRGERVDVAGRHVRLDGVRLETPPAVPPPVLAGVRGPRSLAVAGRVAEGTVLAEPVSPEYARTALGSIASHGPHRLVGYNLAVVHDDGGAAVAAVRPALAPLGEPDWRPHLAPLPFADEVVALRDGCADGAEFARRLPAEWVRQLAVVGTPDQARRRVDVLHEAGVTSTVLIPVGSDPFVSLASLARVL
>CP025990.1|AUS77742.1|1148524_1149394_+|hypothetical-protein
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNQLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSIGRRGDSYDNAPAESVYALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEQRNRRQAMAADGRERH
>CP025990.1|AUS77743.1|1149461_1150322_-|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase
MTTVLSGKVLAAQIKKDTAERVQALTARGVQVGLAIVTATDDEASAWYVRSITKAAAAVGIAGRVEELGVTATESDIRSMLVKLGDDPGVHGIILQTPLPDGVRSERVSVAIAPEKDVDGANPESFGRLATGLRAFAPATAQAVVELLDHHGIDLHGKHAVVVGRSTVVGKPLAHLLLDRHSTVTIAHSRTHGLAEVTSRGDVVVAAVGRARLITADHIGPVAVVVDVGTNPTPEGGLVGDVDPGVTGKAAALSPVPGGVGPVTTALLLRHTVDVAERGGRAAVGS
>CP025990.1|AUS77744.1|1150318_1150939_-|formimidoyltetrahydrofolate-cyclodeaminase
MHRSAIGAFLDELAARTPTPGGGASSALHAAQAAALVGMVGRYSDGAKYAEHADTIGRIVAESDDVREAALAVAARDAAAFEAVGHAYALPRGTEPQEVERRQAIERALVASAAPPVEVVELTDRIVGLAEGLLPIGNRNVVTDIACAAEAARAAAVTARVNIEINRAGIKDEPTRTELAAQAARVQVITKRAERVTSAVLEGISK
>CP025990.1|AUS77745.1|1151888_1152680_+|FkbM-family-methyltransferase
MVMAQEDRLVAYVVPDTTSAGRTHEFLTRSQSGELDGLPSRELPNGMIVLGRNNAEIDFLHQEIFERREYLRHGVTLPRDAVVFDIGAHIGLFSLFVAQNAPDATIYAFEPIPDLRREFALNMSVNGVEAHVFECGVGAEPGTASFTFYPQLSMLSGRFGDESDERAVVEAYALRNAGEGVVGAIAELVTERLRDRHDVVCSVRTVSDIIDEHRVEQIDLLKVDAEMSEAEVLRGIRPEHWSRIRQVVAEVHDRDGRLDMVTE
>CP025990.1|AUS77746.1|1152676_1154005_+|hypothetical-protein
MIARQWIYRPRRDFGSADTQWTYQRHRDQQSAHRNCACGVTRPRARNPGIEDRTSNGIERAVAGLPGAQRLRLPGVAAGLAERQTGPQGASRACPHLVGISAGSRRAPSNPVEEFLCGLFAEAVGLDHVGVDDDFFDIGGHSLLAARLVSSIKASFGVELSISRLFQAPTVAQMSDLFNTGEVSNNEDVLLPIRANGDRPPIFFVHPGIGLSWCYAGFARWLRGPAIYGLQARAVSDADLLAPTLTDMALDYLSRLREVQPAGPYRLAGWSFGGNVAHTIAAMLGEAGEQIDLLALIDCYPYAGGEPGSTAEEPAPDLETVRRLHLDGTALSQVDDGRAAELATVLGHNTRLAVKHDPPLFDGDVLFFSATGDRDIPELKPTAWRRFVTGSLHLHVIAAQHHEMLRPEPLGRIAEVFAEKIERTSRDRDVRQSRRGVPNAGE
>CP025990.1|AUS77747.1|1154131_1155436_+|MFS-transporter
MSAEFVCFDSPTEGTFTVSTKESGGAKVKLGRRFNRLFAATLVSSIGTGMYAAALPLLALQSTSSPLALSAVVMAAEIPWVLLSLHAGVVVDRLDRRRVMVWADLGRFAVLVVLAALILTAQVHLVWLVLAAFLLGVGQVFFDIAAQSAIPHLVSRDPRSLATANGRIAMADSNGEDFVGPPVGSALFGVWNVLPFASNALSFVASGLLIFSIGADAKSKEKPEAPRKSVRSDIVEGIRWLFGNRTLRALATVSCLGNVAATAQFAMLALLAKEVLELPDFGFGLLLTATAVGATVGGLAAGAASKRFGPGTVMLVGKSGVGAAILVLGLVGNSWVAAAMMTVTGALMTAEKVVVSTLRQQIVPDDLLGRVLSSSRLVVMTGGPIGAMLGGVLATVFAVQVSYIVSGVFLILVALAFYPVLNNRALVSATENSA
>CP025990.1|AUS81470.1|1157206_1157992_+|hypothetical-protein
MDLAASINETGTTLPELFQAQVARSPERTAVEFEDVPLSYAELNARANRLAHRLIAHGAGPEQVVALAVPRSEDLVVALLAVLKSGAAYLPIDPSYPADRIAFMLADTSCRIVLVTPETIGVLPELKCPHLLLDSVANGQWPSTDPVDQDRLAPLHQDHPAYTSGSTGRPKRGGAAMRCPGEPGVVARLRIADRPAGPDRAVLRNQLRRLGHGDPVDATPWRVPGHARRADTAQPGAVRALARGQPGQRTARAQRDGRRGV
>CP025990.1|AUS77748.1|1158703_1159129_+|hypothetical-protein
MQQAQCTGHFGGCAVPMRGKFLPEGHCASCGRNRLVDVGYEADCGNALLLCPTGDLDFLRCCAELSWSSHADHDTVGQAEDRVFSETNGLGSVRIESYASAGFGHRRSRVARGRHVEAGRISVVMRCRSPVTSGTVGCRAA
>CP025990.1|AUS77749.1|1160383_1160809_-|SsgA-family-sporulation/cell-division-regulator
MRNDHVTLCSKAVFDLLAPRTPAVPVHVELRYDTRDPYAIVAAFQTGRGGSVEWVFARDLLADGLIAEVGDGDVRLRPAMDNPEVVVIELSSPSGHAMFEASAQELADFLDQTYDVVMPGNENLWVNVDDALARLLPHDRS
>CP025990.1|AUS77750.1|1161169_1161352_+|hypothetical-protein
MSRRRELSRAPDHPPGAATREATHLGTGDAGARRRVAAHQAFPFHDPAATPRAKTAEQVV

Crispr_ID: CP025990_17

• CRISPR_ID: CP025990_17
• CRISPR_location: 2049619-2049711
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP025990_17

Consensus_repeat	Method
CGGCGCGGGCGGCACCCGGCTGGAACAGCGCGGG	CRISPRCasFinder

spacers of CP025990_17

>17.1|2049653|25|CP025990|CRISPRCasFinder
CGACCGGAGCGACGCGGACGGCACC

CRISPR arrays and Neighbor proteins around CP025990_17

CRISPR arrays

The CRISPR arrays of CP025990_17

>merge|CP025990|17|2049619-2049711|CRISPRCasFinder
CGGCGCGGGCGGCACCCGGCTGGAACAGCGCGGGCGACCGGAGCGACGCGGACGGCACCCGGCGCGGGCGGCACCCGGCTGGAGCAGCGCGGG

>CP025990|17|16|2049619-2049711|CRISPRCasFinder
CGGCGCGGGCGGCACCCGGCTGGAACAGCGCGGG	CGACCGGAGCGACGCGGACGGCACC
CGGCGCGGGCGGCACCCGGCTGGAGCAGCGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS78411.1|2057615_2058305_+|vitamin-K-epoxide-reductase	unknown	unknown	gnl|CDD|240605
CP025990.1|AUS78395.1|2041205_2042129_-|UTP--glucose-1-phosphate-uridylyltransferase	unknown	unknown	gnl|CDD|224131
CP025990.1|AUS81580.1|2046410_2047676_-|protease	unknown	unknown	gnl|CDD|273938
CP025990.1|AUS78401.1|2045206_2045413_+|antitoxin	unknown	unknown	gnl|CDD|379416
CP025990.1|AUS78405.1|2052489_2053950_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
CP025990.1|AUS78406.1|2054324_2054741_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81579.1|2045721_2046222_-|molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
CP025990.1|AUS78409.1|2056651_2057074_-|TIGR03668-family-PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|132707
CP025990.1|AUS78398.1|2043404_2044070_+|hypothetical-protein	unknown	unknown	gnl|CDD|274472
CP025990.1|AUS78412.1|2058354_2059173_-|VOC-family-protein	unknown	unknown	gnl|CDD|319911
CP025990.1|AUS78403.1|2049734_2051150_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
CP025990.1|AUS78410.1|2057083_2057362_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS78396.1|2042205_2042802_+|5-formyltetrahydrofolate-cyclo-ligase	unknown	unknown	gnl|CDD|274270
CP025990.1|AUS78408.1|2055676_2056615_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176191
CP025990.1|AUS78407.1|2054957_2055578_+|deaminase	unknown	unknown	gnl|CDD|334719
CP025990.1|AUS78400.1|2044750_2044933_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS78399.1|2044211_2044649_+|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|376605
CP025990.1|AUS78402.1|2048192_2049311_-|galactose-1-phosphate-uridylyltransferase	unknown	unknown	gnl|CDD|238341
CP025990.1|AUS78404.1|2051146_2051851_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|223816
CP025990.1|AUS78397.1|2042912_2043260_+|FmdB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225210

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS78411.1|2057615_2058305_+|vitamin-K-epoxide-reductase	gnl|CDD|240605	cd12922, VKOR_5, Vitamin K epoxide reductase family in bacteria. This family includes vitamin K epoxide reductase (VKOR) mostly present in actinobacteria. VKOR (also named VKORC1) is an integral membrane protein that catalyzes the reduction of vitamin K 2,3-epoxide and vitamin K to vitamin K hydroquinone, an essential co-factor subsequently used in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. All homologs of VKOR contain an active site CXXC motif, which is switched between reduced and disulfide-bonded states during the reaction cycle. In some bacterial homologs, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases which may function as redox partners in initiating the reduction cascade.	5.17105e-71
CP025990.1|AUS78395.1|2041205_2042129_-|UTP--glucose-1-phosphate-uridylyltransferase	gnl|CDD|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	2.41635e-128
CP025990.1|AUS81580.1|2046410_2047676_-|protease	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.33355e-89
CP025990.1|AUS78401.1|2045206_2045413_+|antitoxin	gnl|CDD|379416	pfam14013, MT0933_antitox, MT0933-like antitoxin protein. This family of proteins contains the MT0933 protein, which has been identified as an antitoxin to /protein MT0934. This family of proteins is found in bacteria. Proteins in this family are typically between 61 and 90 amino acids in length.	3.60747e-08
CP025990.1|AUS78405.1|2052489_2053950_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	4.52342e-48
CP025990.1|AUS81579.1|2045721_2046222_-|molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	3.86809e-48
CP025990.1|AUS78409.1|2056651_2057074_-|TIGR03668-family-PPOX-class-F420-dependent-oxidoreductase	gnl|CDD|132707	TIGR03668, Rv0121_F420, PPOX class probable F420-dependent enzyme, Rv0121 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	1.10879e-40
CP025990.1|AUS78398.1|2043404_2044070_+|hypothetical-protein	gnl|CDD|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	9.06545e-12
CP025990.1|AUS78412.1|2058354_2059173_-|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.88147e-25
CP025990.1|AUS78403.1|2049734_2051150_-|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.20932e-50
CP025990.1|AUS78396.1|2042205_2042802_+|5-formyltetrahydrofolate-cyclo-ligase	gnl|CDD|274270	TIGR02727, Uncharacterized_protein_YqgN, 5,10-methenyltetrahydrofolate synthetase. This enzyme, 5,10-methenyltetrahydrofolate synthetase, is also called 5-formyltetrahydrofolate cycloligase. Function of bacterial proteins in this family was inferred originally from the known activity of eukaryotic homologs. Recently, activity was shown explicitly for the member from Mycoplasma pneumonia. Members of this family from alpha- and gamma-proteobacteria, designated ygfA, are often found in an operon with 6S structural RNA, and show a similar pattern of high expression during stationary phase. The function may be to deplete folate to slow 1-carbon biosynthetic metabolism. [Central intermediary metabolism, One-carbon metabolism].	7.94567e-48
CP025990.1|AUS78408.1|2055676_2056615_+|NADP-dependent-oxidoreductase	gnl|CDD|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.78983e-85
CP025990.1|AUS78407.1|2054957_2055578_+|deaminase	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	1.15678e-16
CP025990.1|AUS78399.1|2044211_2044649_+|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.98144e-46
CP025990.1|AUS78402.1|2048192_2049311_-|galactose-1-phosphate-uridylyltransferase	gnl|CDD|238341	cd00608, GalT, Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme contains two identical subunits. It also demonstrates that the active site is formed by amino acid residues from both subunits of the dimer.	5.45921e-113
CP025990.1|AUS78404.1|2051146_2051851_-|DNA-binding-response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.84137e-89
CP025990.1|AUS78397.1|2042912_2043260_+|FmdB-family-transcriptional-regulator	gnl|CDD|225210	COG2331, COG2331, Uncharacterized protein conserved in bacteria [Function unknown].	9.68015e-26

Protein sequences

>CP025990.1|AUS78402.1|2048192_2049311_-|galactose-1-phosphate-uridylyltransferase
MRRTVAQLADGREIIYFDADPAAPTRGASDTRDLPPYQPASEMRRDPLSGEWVAIAAHRQSRTYKPPADLCPLCPSTADRPTEIPEADYDVVVFQNRFPSFGTPPGVPVPVGDERAATVLAGVDGGTLVPSRPAVGRCEVVCFTSDHDTSFAQLTPARARTVVDAWADRTAALAATPGVEEVFCFENRGEQIGVTLHHPHGQIYGYPFVTPRTARLQAQAERHHASHGRPLLGDVLDAERAAGTRVVAENEHWTAFVPAAARWPVEVQLVPRRQVADLPALTSDERDAFVPLYLDLLGRLDRLHDQPLPYVAGWHQAPVRADRERSWLRLEVFSVLRGPDRLKYLAGSESGMAVWIGDVLPERVAQRLRELG
>CP025990.1|AUS81580.1|2046410_2047676_-|protease
MPYSSSAQHHGGQYQYPGSQYGAGSGAHGGSGQPGPFQPVPEHGFGNNPEHHRPAAAGRGKGTGRLVAGVAALALLAGAVGGGVTGWIVSERAGGGSSVSALDQQPPARNASNAPEGSVQQVAEKVLPSVTQLQVRGQSGAGEGSGVVLSSDGLILTNNHVVEPAVQGGQIVVAFADGTTAPAEIIGRDPSSDLAVVKASGVSDLTPAELGRSDDLSVGQDAVAIGSPFGLTGTVTSGIISSLDRPVRAGGEQGTEATVLDAIQTDAAINPGNSGGPLVDMEGRVIGINSAIYSPGAGTGQAGSVGLGFAIPIDQARRIADELRENGVATRAVLGVQLAVDSRQNGADVAQVIPGGAAAEAGVEEGDVVTKLNDRVIQSSDALIAAVRSEEPGATVTLTVRNQGGGDEREIQVTLGSETVG
>CP025990.1|AUS81579.1|2045721_2046222_-|molybdenum-cofactor-biosynthesis-protein
MERSPQRLGRALVVIVDDRVAQGEHGDSIGPLVTELLEEAGFIVDGTVAVAGEVVDIRNALNTAVIGGVDVVVTVGGTGVSPRDVTPDATLGVLDRPIPGIAEALRASGLAAGAVDAGISRGLVGVSGSTLVVNLAGSRAAVRDGMATLTPLVTHVIEELSSLDTP
>CP025990.1|AUS78401.1|2045206_2045413_+|antitoxin
MNGFLDKAKELAQQAREKAAQGVDAAASKVDEMTGGKYTEHIENVSNKVENALDPNAGDEGQNKDGRA
>CP025990.1|AUS78400.1|2044750_2044933_-|hypothetical-protein
MAERDRPERGRRRVTRPADVVGELLPDTTSDERDDQERYWQERSAEDWYRENRPPHHDGG
>CP025990.1|AUS78399.1|2044211_2044649_+|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKDFLMRGNVVELAVAVVIGSAFTAIVTAVTENLIQPILDAVGPADVGNLGIRIGTSPDGTPITVDFGGVITAGINFLMVAAVVYFIFVLPMNKLQERRQRGEEPAAATPTELELLTEIRDLLREQRRTAEEGAVLERDRG
>CP025990.1|AUS78398.1|2043404_2044070_+|hypothetical-protein
MRGGTGRGASSLSSSVWRRCRAALPPWSGPPRAVTLLRLAVAAALAVVGLVLLPGHDVPHREGRADTVTTLVAATDLAPGTPVDVSAVRGAQLPPEAVPAAALTAPDQAAGRFPLVPVQAGEVLTEARFAVAGRPGHIAVPVRPHDPAVVDLVRPGARVDLVSLDPGGAGHVLATDVTVVSVVDADGAATQGSFVVVALPETLGHQVAAATLRTQITITLR
>CP025990.1|AUS78397.1|2042912_2043260_+|FmdB-family-transcriptional-regulator
MPTYQYACTACDHRFEQVQSFTDQALTACPECQGKLRKLFSSVGVVFKGSGFYRTDSRSSGGGTAAKSSSSSSEGATKSGDSGSSSNSSSSSNSSSSDSGKSTASSGSSKAASTS
>CP025990.1|AUS78396.1|2042205_2042802_+|5-formyltetrahydrofolate-cyclo-ligase
MPPEGTSSAKRTWRRRLLAARRAVPPEQRRAEAERITAVISEVARDRAGTTVAAHVPFGTEPGSLHLVDALREGGCRVLLPVVVEPDGPMRWAEYGGEAMLRPGNLGVLEPSGPLLAPEALSEATAILVPALAVDRAGVRLGRGGGCYDRSLPLAAPSTLTAAVVRDAELVDQLPHGPHDALLTSVITPGRGLLHLPR
>CP025990.1|AUS78395.1|2041205_2042129_-|UTP--glucose-1-phosphate-uridylyltransferase
MSPTSAFQTAIVPAAGLGTRFLPTTKSVPKELLPVVDTPAIELVAGEAAEAGAERLVIVTSPEKSSVARHFEPRPELERTLEERGKTALVEKVRRAPQLIRAEVAIQEQALGLGHAVACARPNLNDSDEAVAVLLPDDLVLPTGVLSRMAEVRERFGGSVLCAFDIPREQISAYGVFEVEDTGVEDVLRVHGMVEKPAPEDAPSTYAAAGRYLLDRAIFDALDRITPGAGGELQLTDAVALLISEGHPVHVVVHRGGRHDLGNPGGFLRAAVDFALSNPEYGPELREWLRHVVADPAGTIEGGTRSN
>CP025990.1|AUS78403.1|2049734_2051150_-|sensor-histidine-kinase
MTDAHRPPQRTVGIERWNDWHQRMALRTRVSMLAAICVGAAVALVSLGAYLAVHKSLYDELDRSLTQRATQAVGESMAASQLRSAPAVVLVASDVQLGLVYASGEVLSAGTRAPATGRAELAVARGELPRSLRTDTATDTRVIALPIGTGAALVVAQPLDSIRGTLGLLSVVLAVVGGAGIVVAAIAGTAVARAALKPVERLTAATERVATTGDLRPIVVSGDDELARMTMSFNTMLGAVAESQERQRRLVADAGHELRTPLTSLRTNLELLVASSKPDAPQLSPQDRMEIYEDVRAQINELSNLVGDLVELAREDAPQVVHEPVELVDVVERALDRARRRAPGIAFEVRPHPWTLLGDANALERAVLNLLDNAAKWSPPEGTVLLTMTPENDTTIRVEVADSGPGIAPADLPHVFERFYRSPEARTLPGSGLGLAIVSQAAERHGGTVRAGRADTGGALLTLRLPGRAGV
>CP025990.1|AUS78404.1|2051146_2051851_-|DNA-binding-response-regulator
MRILVVDDDRAVRESLRRSLRFNGYQVELAADGQQALAAVMGLAPDARPDAMVLDVMMPRLDGLEVCRRLRGVGDDLPILVLTARDAVSDRVAGLDAGADDYLPKPFALEELLARLRALLRRRGPANPAEDEVDVLSFADLELDTGTREVRRGERRISLTRTEFALLELFIAHPRRVLTRTRILEEVWGYDFPTSGNALEVYVGYLRRKTEAGGEPRLIHTVRGVGYVLRETPP
>CP025990.1|AUS78405.1|2052489_2053950_+|GGDEF-domain-containing-protein
MRFLVESGQTDEANTLLDAVLERPDPRTGWHRVAMLVNRAIAAWRLDRLTLALELAAEGWTELDAERPEGRTAAHTLGLLGHLIDSMGHRRAALDMLRLSVEVARGTEDDATLAACLQRLGGTLNMLASQEASENAGAVFAESRSLLAEGLSLVEGGRVHRSLLVAHARSLVGVGRLAEAEEECSRALLLAEAADDGWAAATARWVLACSARDRDDLVPARALAAEALDGVERTGDTTLINRFAEDLADICAGLGDHRGEANALRRGLAASRKVTETLKEAMGQALEQRRLAVQAHRAAVAAREAAARDPLTGLVNRLGLERSAPRLIKRTASKGRVPWLVLVDVDWFKDVNDDAGHAAGDAALREIAQLLRRECRADDLVARWAGDEFVILLVDATENRLDAGPVVAERIRAAVDTHDWRTVLGKTTRPPTVSIGVAAGPSQLDQLFTAADVALYRAKQQGRNRVEVQPPPEDKGFTPRQSLSGS
>CP025990.1|AUS78406.1|2054324_2054741_-|hypothetical-protein
MADDPIEEPAFEPSPEDVASVLAWFDDYDELAATAQVERMADLAMFPLNSVTDDAEGNGSASWSDREQYVREMTEIVGDGARMESVRTPHFLSRSLVFVVTDATYTHDGVRHRMRYGDLLIRREGRWYFQTMVQGGWG
>CP025990.1|AUS78407.1|2054957_2055578_+|deaminase
MGQITVTTQLSLDGVVQSPGAPEEDPSGGFDRGGWVAPHVDDDMLRIIAEDFGRAGAFLLGRRTYEIFAAHWPLVTDRQDPIATALNTLPKHVVSGTLGTPGWAGTEVVRGDLVTEVTRLRDTTDGELQVHGSITLVRALLEADLVDEYRLWTFPVVVGAGRRLFAEGLPSRTVRLVDTASTDAGAIRARYQPVGPARFGSLALGG
>CP025990.1|AUS78408.1|2055676_2056615_+|NADP-dependent-oxidoreductase
MRALVATDYGALDQALVLASVPEPVPAPGQVLVRVRAAALNPLDLALILGSMREQMPIAHPFTVGMDAAGVVVAVGDGVRDHAPGDEVLGYSAFVSGTVAEYTLIESGPYLASRPAGLDPVRAAGVPESGLTATHLLRAAGLRPGSSMLVIGATGGIGLYTVQLATAAGVEVLATGKPTDRDYVRSLGAVEMVDYTRGQVVRDALALRPDGVDVVLDLVNAGPDIVASAEAVRPGGRVVSPLGGPTELGRGVTAHYIGQMTPRPGDLAELAARAASGRLRVEVGAVYPLDEAKQAVTDFASRHIHGKVVVRI
>CP025990.1|AUS78409.1|2056651_2057074_-|TIGR03668-family-PPOX-class-F420-dependent-oxidoreductase
MPTLTSERCRSRFAGSPVARLATVSGGGQPHLVPLTFAVLPDDPDVLVSAVDRKPKSGRRLRRLDNIRDDPRFSALVDSYDADWSALWWVRADGIAEVREEPDESAARALRTKYPQYRDADPFDALVLLRVRRWSGWTAT
>CP025990.1|AUS78410.1|2057083_2057362_-|hypothetical-protein
MGGFIEAHLVPVLFIGAFVVVFSGAVGAMLTRVGMRTMILALAILGISFVLVVPIIPLLVCAAVGVPVGYVVHRRVRQRYSEAAEPPLGAGR
>CP025990.1|AUS78411.1|2057615_2058305_+|vitamin-K-epoxide-reductase
MSEQLATHTVDSEGPSGKASPDSREPGQTGSEDLLGAPSPTRGLGWLLTVGGFLGFLASFVLMVERIELLKDPLYIPSCSLDAVLSCGSVMTTPQAALFGFPNPLIGVAAFPAVVTVGAAVLAGARLPRWFWLGLQLGATLGTVFVHWLMFQSFFNISALCPYCMVVWAVTVPIFWYTTTHNIERGHLRLGGFGRALVAYRGPVLAAWALSVVGLVVAVFWTHWSQLLS
>CP025990.1|AUS78412.1|2058354_2059173_-|VOC-family-protein
MAVLETGTDLLYGSLPAGLPCWIDLRTPDLPAAEDFYHRLFGWEYHQEDGYTLALLDGYPVAGLCPSQDSAPAWTLYLAADDVERTSERVRETGGRLLRPSAEVPGVGLRAVARDPHLAEFGFLRASRSWQFHVGVPGSLMWGELITTGPRTADEFYGDLFDFRVDQHGRGATADFAVWYSGGESVLARVRMVPDVVRTKPHWLIYLGVRPEDGVDEVLRRAVTAGAEVRVDPFDGSYGRVAVIRDTAGARVALLDQTRAVGWGHDHDPYDD

Crispr_ID: CP025990_18

• CRISPR_ID: CP025990_18
• CRISPR_location: 2981839-2982294
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of CP025990_18

Consensus_repeat	Method
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CRISPRCasFinder
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CRT

spacers of CP025990_18

>18.1|2981868|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CAGCCCCGGACGAGACCCTTCGCGGAGGACCC
>18.2|2981929|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GATGCCCTCGACATCGGTCGGCGTCTCCCCTT
>18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGCGTGATGGCGGAGATCGCCTGGCCCACTAT
>18.4|2982051|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCGGACACGGCGTAGGCGACGCCGCAGCTCAC
>18.5|2982112|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCGTGTACCAGGGGCAGGAGTACACCGCGAG
>18.6|2982173|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCCGACCGCACCCGTCACACGTGTGACGCCGT
>18.7|2982234|32|CP025990|CRISPRCasFinder,CRT
CCGCCACCTGCCGGCCGCATCCGCACCCCCCG

CRISPR arrays and Neighbor proteins around CP025990_18

CRISPR arrays

The CRISPR arrays of CP025990_18

>merge|CP025990|18|2981839-2982294|PILER-CR,CRISPRCasFinder,CRT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGCAGCCCCGGACGAGACCCTTCGCGGAGGACCCGAAAGCCCCGCGCAAGCGGGGGTGAGCCGGATGCCCTCGACATCGGTCGGCGTCTCCCCTTGAAAGCCCCGCGCAAGCGGGGGTGAGCCGTGCGTGATGGCGGAGATCGCCTGGCCCACTATGAAAGCCCCGCGCAAGCGGGGGTGAGCCGTCGGACACGGCGTAGGCGACGCCGCAGCTCACGAAAGCCCCGCGCAAGCGGGGGTGAGCCGGCCGTGTACCAGGGGCAGGAGTACACCGCGAGGAAAGCCCCGCGCAAGCGGGGGTGAGCCGCCCGACCGCACCCGTCACACGTGTGACGCCGTGAAAGCCCCGCGCAAGTGGGGGTGAGCGGCCGCCACCTGCCGGCCGCATCCGCACCCCCCGGAAAGCCTTGCGCAAGTGGGTGAGCCGCG

>CP025990|18|14|2981839-2982233|PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CAGCCCCGGACGAGACCCTTCGCGGAGGACCC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GATGCCCTCGACATCGGTCGGCGTCTCCCCTT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TGCGTGATGGCGGAGATCGCCTGGCCCACTAT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TCGGACACGGCGTAGGCGACGCCGCAGCTCAC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GCCGTGTACCAGGGGCAGGAGTACACCGCGAG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CCCGACCGCACCCGTCACACGTGTGACGCCGT
GAAAGCCCCGCGCAAGTGGGGGTGAGCGG

>CP025990|18|17|2981839-2982294|CRISPRCasFinder
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CAGCCCCGGACGAGACCCTTCGCGGAGGACCC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GATGCCCTCGACATCGGTCGGCGTCTCCCCTT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TGCGTGATGGCGGAGATCGCCTGGCCCACTAT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TCGGACACGGCGTAGGCGACGCCGCAGCTCAC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GCCGTGTACCAGGGGCAGGAGTACACCGCGAG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CCCGACCGCACCCGTCACACGTGTGACGCCGT
GAAAGCCCCGCGCAAGTGGGGGTGAGCGG	CCGCCACCTGCCGGCCGCATCCGCACCCCCCG
GAAAGCCTTGCGCAAGTGGGTGAGCCGCG

>CP025990|18|14|2981839-2982294|CRT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CAGCCCCGGACGAGACCCTTCGCGGAGGACCC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GATGCCCTCGACATCGGTCGGCGTCTCCCCTT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TGCGTGATGGCGGAGATCGCCTGGCCCACTAT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TCGGACACGGCGTAGGCGACGCCGCAGCTCAC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GCCGTGTACCAGGGGCAGGAGTACACCGCGAG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CCCGACCGCACCCGTCACACGTGTGACGCCGT
GAAAGCCCCGCGCAAGTGGGGGTGAGCGG	CCGCCACCTGCCGGCCGCATCCGCACCCCCCG
GAAAGCCTTGCGCAAGTGGGTGAGCCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79071.1|2982462_2982645_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS79073.1|2984133_2984565_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79074.1|2985166_2986162_+|hypothetical-protein	unknown	unknown	gnl|CDD|188593
CP025990.1|AUS79066.1|2974994_2975747_+|phosphoglyceromutase	unknown	unknown	gnl|CDD|184519
CP025990.1|AUS79065.1|2972320_2973883_+|D-inositol-3-phosphate-glycosyltransferase	unknown	unknown	gnl|CDD|132490
CP025990.1|AUS79067.1|2975875_2977084_+|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|274368
CP025990.1|AUS79077.1|2988283_2989792_+|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|235095
CP025990.1|AUS79079.1|2991453_2991666_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
CP025990.1|AUS81711.1|2973918_2974395_+|histidine-kinase	unknown	unknown	gnl|CDD|371210
CP025990.1|AUS81713.1|2989827_2990220_+|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS79064.1|2970904_2972146_-|SGNH-hydrolase	unknown	unknown	gnl|CDD|238868
CP025990.1|AUS79076.1|2987948_2988245_+|hypothetical-protein	unknown	unknown	gnl|CDD|377508
CP025990.1|AUS81712.1|2979587_2980511_+|hypothetical-protein	unknown	unknown	gnl|CDD|224007
CP025990.1|AUS79072.1|2982641_2983475_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS79063.1|2970390_2970588_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79068.1|2977080_2977761_+|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|223816
CP025990.1|AUS79069.1|2978274_2979582_+|hypothetical-protein	unknown	unknown	gnl|CDD|368953
CP025990.1|AUS79075.1|2986158_2987952_+|hypothetical-protein	unknown	unknown	gnl|CDD|238949
CP025990.1|AUS79070.1|2980637_2981519_+|proline-dehydrogenase	unknown	unknown	gnl|CDD|223580
CP025990.1|AUS79078.1|2990442_2991279_+|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl|CDD|237008

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79072.1|2982641_2983475_-|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	7.57079e-10
CP025990.1|AUS79078.1|2990442_2991279_+|pyrroline-5-carboxylate-reductase	gnl|CDD|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	2.08244e-105
CP025990.1|AUS79074.1|2985166_2986162_+|hypothetical-protein	gnl|CDD|188593	TIGR04078, radical_SAM_domain_protein_protein, peptide modification radical SAM enzyme, YydG family. Members of this radical SAM protein family for peptide modification occur only in the context of members of family TIGR04077, which average about 50 amino acids in length. In Bacillus subtilis, this protein (YydG) appears to act on its cognate target peptide (YydF) prior to its export, and result in the creation of a signaling molecule that induces the LiaRS two-component system. [Regulatory functions, Protein interactions].	2.55228e-23
CP025990.1|AUS79066.1|2974994_2975747_+|phosphoglyceromutase	gnl|CDD|184519	PRK14120, gpmA, phosphoglyceromutase; Provisional.	1.10344e-179
CP025990.1|AUS79065.1|2972320_2973883_+|D-inositol-3-phosphate-glycosyltransferase	gnl|CDD|132490	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase. Members of this protein family, found exclusively in the Actinobacteria, are MshA, the glycosyltransferase of mycothiol biosynthesis. Mycothiol replaces glutathione in these species.	0
CP025990.1|AUS79067.1|2975875_2977084_+|two-component-sensor-histidine-kinase	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.02966e-74
CP025990.1|AUS81713.1|2989827_2990220_+|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	3.32192e-07
CP025990.1|AUS79079.1|2991453_2991666_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.24317e-15
CP025990.1|AUS81711.1|2973918_2974395_+|histidine-kinase	gnl|CDD|371210	pfam10722, YbjN, Putative bacterial sensory transduction regulator. YbjN is a putative sensory transduction regulator protein found in Proteobacteria. As it is a multi-copy suppressor of the coenzyme A-associated temperature sensitivity in temperature-sensitive mutant strains of Escherichia coli the suggestion is that it both helps CoA-A1 and possibly works as a general stabilizer for some other unstable proteins. This family was expanded to subsume other related families: DUF1790, DUF1821 and DUF2596.	1.02147e-16
CP025990.1|AUS79064.1|2970904_2972146_-|SGNH-hydrolase	gnl|CDD|238868	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	5.71856e-59
CP025990.1|AUS79077.1|2988283_2989792_+|lysine--tRNA-ligase	gnl|CDD|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	0
CP025990.1|AUS81712.1|2979587_2980511_+|hypothetical-protein	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	4.88585e-24
CP025990.1|AUS79076.1|2987948_2988245_+|hypothetical-protein	gnl|CDD|377508	pfam05402, PqqD, Coenzyme PQQ synthesis protein D (PqqD). This family contains several bacterial coenzyme PQQ synthesis protein D (PqqD) sequences. This protein is required for coenzyme pyrrolo-quinoline-quinone (PQQ) biosynthesis.	7.61076e-12
CP025990.1|AUS79068.1|2977080_2977761_+|DNA-binding-response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.79287e-95
CP025990.1|AUS79069.1|2978274_2979582_+|hypothetical-protein	gnl|CDD|368953	pfam06524, NOA36, NOA36 protein. This family consists of several NOA36 proteins which contain 29 highly conserved cysteine residues. The function of this protein is unknown.	1.33755e-05
CP025990.1|AUS79075.1|2986158_2987952_+|hypothetical-protein	gnl|CDD|238949	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. The three-dimensional architecture of the N-terminal domain of asparagine synthetase B is similar to that observed for glutamine phosphoribosylpyrophosphate amidotransferase while the molecular motif of the C-domain is reminiscent to that observed for GMP synthetase .	7.87219e-21
CP025990.1|AUS79071.1|2982462_2982645_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	8.50505e-14
CP025990.1|AUS79070.1|2980637_2981519_+|proline-dehydrogenase	gnl|CDD|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	0.000194971

Protein sequences

>CP025990.1|AUS79070.1|2980637_2981519_+|proline-dehydrogenase
MPSRARVLLTSAALAAARNDAVRGRSVVTRRRTRQNAGKDAVGAVLAARRLVARFGRVRLDHLVEGATDRGAAVRATQELLDLLGEIDLSGLAPFVDVGLRPSGCGLALDVGLAEENLDRICGLAHRVGCTVTLDTEDHSSVDQVLAVAGSLRDRWRGLGVVLHANLHRTVEDCVAHSRAGSRVVLSPASHPESASVAVFDPHEVDLQYVRCARVLLAGACRPVFAARRPRLLGAVVGAARWHRRDVRSFECQVPPWMPPSDRRRLAGAGVALRAVVRFGADAGPPVVPRPGH
>CP025990.1|AUS81712.1|2979587_2980511_+|hypothetical-protein
MGDGVRIPVGLSTASVWPEPAEGAFRLAAELGYDGVEVMVWADPVSQDPEAVRRLAGQYRVPVLAVHAPCLLITQRVWSSDPVERLRQAVRAAQTLDAATVVVHPPFRWQRRYADMFADLVAELEDDTGITVAVENMFPVRPLGNRQLGTRPPGSGPLSSRLMNSQLMGAYLKGEQLIGSQLRDSWPPRVSAFHPSPDPTEAGYRSYTLDLSHAAVAHADAMLLAARMGSGLRHVHLGDGTGAPRDEHLLPGRGNQPCAELLRSLRPSGFDGSVVLEVNTRKARAPGERAAELTEALLFARKHLGPE
>CP025990.1|AUS79069.1|2978274_2979582_+|hypothetical-protein
MSRDNRSESEGQRSVAELLAAYGGKGGGGRRRRRRAEDPTDTAPQAIIDRVLSESGNLRRVEEADEAPGPEGQQYQPPPRPAPVGQDRPTPSPHPEPPHHPAEPDYPRNDYPQGDYPEDDYPTASDYPRGDYPVDRGQRGQVDGPGPQPEAGARPAFPAAGQLPADQTVLYPVDPDMTAQYPPLTGEAPAVASDVGGRLDAPPDDPHTEQFPRVAGDNFGGSILDDPAGTLDAGSDAERTVVGTGWFETGEVAAYREDGPDPSAGPAETRQQAPVAPGVDVDPDAGERPADRRDDADDHDYEPGDYGADDYGSGDYEPDDYGADDYDEDYDEDDSAEEGVEEPAEKPVSPVKEWLLMIGQLVVGVVGGAGLWLVFQWLWLNIPAVALVVALLVITGMVFLVRKIRRSDDLQTTLFTVLVGLIVTVSPAALLLLGT
>CP025990.1|AUS79068.1|2977080_2977761_+|DNA-binding-response-regulator
MTRVLIVEDEESFADPLAFMLRREGFTPAVATDGQQALAEFDRNGADIVLLDLMLPGMSGTDVCRQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGESEETAPQVLAAGPVRMDVERHVVTVGGGDVTLPLKEFDLLEYLLRNSGRVLTRAQLIDRVWGADYVGDTKTLDVHVKRLRSKIEPDPGNPRHLVTVRGLGYKFEA
>CP025990.1|AUS79067.1|2975875_2977084_+|two-component-sensor-histidine-kinase
MGYLALSISLVLVGGLLGFVAGRLSERRPRRGHGGVTVAELLRRLVNSSHSGVAVLNRFGDVLFHNQRAVELGVVTANVIDPRAGQAADLALAENRVVAVDLPPTGAVRKRRPEAVAAEVRPLGEGFTVVDAADESEAVRLEATRRDFVANVSHELKTPVGALALLAEAMLDAADEPDEVRRFSEKIRHEATRLGALTSELIVLSRLQGAEPLPDPDPVSVDAVVDEALGRCRLTAEAAGITVTTDPRSGLVCAGDRVLLTTALSNLLTNAIAYSPEGSAVSVSRRLRDGMVEVAVTDRGLGIAPEHQERVFERFFRVDPARSRATGGTGLGLAIVKHVANNHGGSVRLWSLPGTGSTFTLSLPALDAEEPRAGTERPLAAASAGGPGTTISSQPRNPGGKP
>CP025990.1|AUS79066.1|2974994_2975747_+|phosphoglyceromutase
MTKAVGTLVLLRHGESTWNAENLFTGWVDVPLSEKGQAEARRGGELLAEAGLLPDVLHTSLLRRAISTANIALDVADRHWIPVRRDWRLNERHYGALQGKNKKQTLEAYGEERFMLWRRSYDTPPPEIEPGAEYGQDGDPRYAELGDELPRTECLKDVVARLLPYWESSIVPDLRAGRTVLVAAHGNSLRALVKHLDGVSDEVIAKLNIPTGIPLRYDLDEQLMPVVPGGTYLDPDAAAEAIDAVANQGR
>CP025990.1|AUS81711.1|2973918_2974395_+|histidine-kinase
MRTVERTLRDRDLDFDHASPGRFLVRLPGERKQRTSCWLVVGRHGLLVEAFVCRRPDENQAGVHHFLLRRNARLYGVHYTVDEDGDIHLVGRLGAHAVTEDELDRVLGQVLEAADGDFNKLLELGFAGAIRREWAWRRSRGESLANLAAFEHLARDQR
>CP025990.1|AUS79065.1|2972320_2973883_+|D-inositol-3-phosphate-glycosyltransferase
MTGSEHRGAGRPGKVDYTWLSVGSCARQPRRFDSLVAADPPIEEGLLVSDSLRVITGGEGRSATSAGSGSPRRVALLSLHTSPLEQPGTGDAGGMNVYVLQTARRLARRGVEVEVFTRATSSEHPPLVRVEPGLLVRNIIAGPFEGLGKNDLPAQLCAFAAGVLRVEARHEPGYYDLVHSHYWLSGQVGWLARERMGAPLVHTAHTLARVKNAALAEGEPAEPRVRVIGEQQVVDEADRLVANTSVEAEQLVRLYGADPAAVVTVEPGVDLDCFTPGERSEARRTLRAAGVVLPPDPVVLTFVGRIQPLKAPDVLLRAAARLLAEEPRLRGRLAVLVVGGPSGSGLQEPEALQKLAGELGITDVVTFLPPRSGAELADVYRASDVVAVPSHNESFGLVALEAQACGTPVVAADVGGLSVAVVDGSTGLLVPSHAPEDWAAALRAVALPATGSPDEVPESVRSRAAGVRPENAVRHANDFSWDRTTDGLLRAYRQAALAFGRGVRDAGGGRNRHGRRGGEA
>CP025990.1|AUS79064.1|2970904_2972146_-|SGNH-hydrolase
MVRLLLIVVCCLGLLVSAEPVVPPTPLSPGTAEPVPTTGVTTWAAPQMPAQPNQREELGFANVTLRTMVRISAGGSGVRVRLDNTYGDRPLRIGAASVALADGFDGSSLPGTVRPLLLDGRSDFTVPPGHHRYTDPAGLDVPDRARLHVSLFLPGPTGPLGNHPISGEPTLLARGDHTENPTSDRFRPVEHRAVVDAVLVLGSEASGTVVAVGGSLTDGLGVDFPESGRWPDVLADRLLSLPPGRRLAVANSGLSGNRILLGSVGGGPRLLDRYDTDVLSLPGAAAVILAVGTNDIQQTPHETDARTLFAAIDDLARRSRDAGLRVVVATIPPFGSWETWKPELETTRTRVNALIRTHADEYDAVFDLDTLLRDPDDPELVRPDLDLGDGLHLNQRGYTLVGESVPVEALLPR
>CP025990.1|AUS79063.1|2970390_2970588_-|hypothetical-protein
MRSSRKSGRSRPSPPHPRQPRKGNGSSRGSPTTPSAPGCASAPVVRRSVCGSTTPSAPTSCTSAG
>CP025990.1|AUS79071.1|2982462_2982645_-|DUF397-domain-containing-protein
MTRWRKPRRSVSSSNCVEIGTGASEVVGIRDTKNRDGGTLLVHRAAFAALVDAVKADRLH
>CP025990.1|AUS79072.1|2982641_2983475_-|XRE-family-transcriptional-regulator
MARSPAVLALGRALAQARTAAGLSQQQAARQLGVSQSLISRSERGSRTPDGSAVDRMIELYDPPGALRAELGKLVDTVTVQQWSPVGSDEIAESLTDLERYERDASSITEVHPVLVPGPLQTREYAAALLAHGETPAIDMDQALAMRERRRAHVLGGDVGYLAIIDELALRRTTPPGGVDVRRGQLAALREWSRLPAVSVRVIPAERGFYRGLVAGFEIIEFDDAPAVVHLEHYRSSTWLYSERDVAPVVATRDHLLGVALSEEESRTRLRALEGEL
>CP025990.1|AUS79073.1|2984133_2984565_+|hypothetical-protein
MDGAGAVTAPARRTSRQCSATVPAVDPTGRLTTLALTLTVERSAVALAGSGTRFLVLPSGVRQVAAALRTRRRLAVSAHIGPTTRTLSVAPTAMPGALASGARLTLRSASQVAAYWPLMLGPGPARSLARLLDQAADQCQPRR
>CP025990.1|AUS79074.1|2985166_2986162_+|hypothetical-protein
MRYNTLGIHMTNTCQLSCDHCITDSSPTASGDLEWAQIEAAIRAAASHVDGVCVTGGEALIRRSRTLRTIRLTRELGLISSLVTNGYWARREAFAQRTLDELVTAGLHKMAVSYDTYHERFLGPEVYARLLALGTDTDIVIKLQYCGDGRDEAYRNAVALASRYGVELDRAEVLPFGRGSALVPAGVPAVDEVPNGPCGVVVRPVLTPENELFTCCGPARGSHPHSPLRLEITTTSDVGSALGEAEADPILNVIHSHGPRRLFDYLDPSTRDRITGRLRDPSLCSMCRAITDDPDAVAELTRALDPQRLRLIALSAVLHDAREDQKRRSAS
>CP025990.1|AUS79075.1|2986158_2987952_+|hypothetical-protein
MTGLALAVVPDQPRGTVQAMLAAIGRDISTWNIAEGPGAALGVGVVNQGSPTAEMLTLPGGVRIAVDAPGWVRRDLASRLHRLRECETRTTPAALVGLFASIAGDGHCVAVVPDLGCVAYRGPMSPRPLFYTCDEGSILVASQIRALNAARPTEIDADGLASFLVPQLCDPRGTTWKAVRRLPPGYVLTTGDGTVDVRPVAQVEPLDSRGASRSDFITEFRERFLMAVRRCSGPSTGILLSGGIDSSALACASTAVSDTPGRAYVLDYEAPLTSCDERRFADDVIATCGLEAVRVPGNRLLPLVADYPHSDEPEAWAYSGRNWAMLRRIAAGMPAPTTVLAGEGGDELLLGQVFAVADRIALGDTDAAHRELATFPDPDGTAKVVHRLLAGDYDTRGARVIRALRELPPWLSTAYVESVGIVDQLASTYPSLSPPGHIASSYSRALVAEAGAAGRAQCGGWWPDMGHRVGLTITYPFLDPDLAALVWSLPPVLLRDMGEEKVVLREALADRLPISVARRRDKAEALALLRAGLVEGIDQLHSMASESPLNDLGIIDCARLRNGIDRYAAGESGLGPALWATVSTHRWLTEINRGAPS
>CP025990.1|AUS79076.1|2987948_2988245_+|hypothetical-protein
MSANYLPCRVPATMTKIGVHWVIVPVDDAEVALINETGRTIVEQCDGTRTVEDLVHAVAGAGVEHDIALADVTEFLNRLYSSGLLKRVLGPTPLDHVG
>CP025990.1|AUS79077.1|2988283_2989792_+|lysine--tRNA-ligase
MSDTADDLADLTTLPEQIRVRREKLDRLRAAGADPFMQRSPRTISIGDVREKHGHLEPDHSTGEQVGVAGRVMLYRTGGKLCFATIRDATGDLQIMLSLDRLGEEALAAWKSDVDLGDHVGIEGEIITSRRGELSVMADRWVLTAKALRPLPEKHKGLTDPEARVRRRYVDLIVNPEAREMALRRSAAVRALRDGLHEQGFVEVETPMLQQVHGGATARPFTTHINAYDLDLYLRIAPELYLKRLVVGGMDKVFEINRNFRNEGADSTHNPEFTMLEFYQAHADYDEVARVTRELVQGVARAVLGGTVIERDGTEIDIGGDWPSITLYGSVSDALGEEITPHTSVETLATLADAHGLGRDVRWGNGKFTEYLFEELVEPTIVQPTFVRDFPLETSPLTRQHPDEPLLTEKWDLIGWGMELGTGFTELTDPLEQRRRLTEQSLLAAGGDAEAMQLDEDFLEALEYGMPPTGGVGVGVDRLLMAFTGRGIRDTILFPIVKPNVQ
>CP025990.1|AUS81713.1|2989827_2990220_+|hypothetical-protein
MTRGGWVRRTIARSRGAWLPHTRAVDGDVLSRGRPAELWSRQGGGGGGGHDLRKLTCCSAWSSHSECRPVSVTVSPFRSDGEPVEFDQSVPLFFPSLASLPIEQVRRAVAEYFQTGRRPDCVQRQPGDWY
>CP025990.1|AUS79078.1|2990442_2991279_+|pyrroline-5-carboxylate-reductase
MSSIAVLGAGKIGEALLSGLIRAGHQPDTLSFTERHPGRAKELAGRHGVDAVAVAEAAVNADVLVVAVKPQDIEPLLDDLSGSVAERPADRGLPLVVSLCAGLPTALYESRLPPGTPVVRAMPNTPMLVGEAMSVISAGSHASEDDLSLVEELLASVGRVLRVPEEQQDAVTALSGSGPAYFFYLVEAMIDAGILLGLPRAAAAELIIQSAVGAATMLRGSESHPVILREAVTSPAGTTIAGIRELEKHGVRAAMIDAIEAARDRSVELGRAHEGTGS
>CP025990.1|AUS79079.1|2991453_2991666_+|helix-turn-helix-domain-containing-protein
MLTQREHDNGFGQVRFLTVAEVAAMMRVSKMTVYRLVHSGELPAVRVGRSFRVPEKTVHAYLQKSYYDVG

Crispr_ID: CP025990_19

• CRISPR_ID: CP025990_19
• CRISPR_location: 3490633-3490993
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of CP025990_19

Consensus_repeat	Method
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRT

spacers of CP025990_19

>19.1|3490663|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
GAAACCGCACTTCAGGTCGCCGCGTACAGGTACGC
>19.2|3490728|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACAACGCCGACCACATCCACCTGGCCGCGATCCTGCT
>19.3|3490795|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCGGGCTGGCGGAAGTCGCGGCGCAGCGCGAACCAGA
>19.4|3490862|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCCCTCCCCGCCGTCCTCGTCGGACTCGGGCTCGC
>19.5|3490927|36|CP025990|CRISPRCasFinder,CRT
CGTCCGACACGCGCCCCATCTCGCTGGCCTCAATGC

CRISPR arrays and Neighbor proteins around CP025990_19

CRISPR arrays

The CRISPR arrays of CP025990_19

>merge|CP025990|19|3490633-3490993|PILER-CR,CRISPRCasFinder,CRT
GTTGGAACTCCTCGTAGGAGCGATGAGGACGAAACCGCACTTCAGGTCGCCGCGTACAGGTACGCGTTGGAACTCCTCGTAGGAGCGATGAGGACACAACGCCGACCACATCCACCTGGCCGCGATCCTGCTGTTGGAACTCCTCGTAGGAGCGATGAGGACCCGGGCTGGCGGAAGTCGCGGCGCAGCGCGAACCAGAGTTGGAACTCCTCGTAGGAGCGATGAGGACCCCCTCCCCGCCGTCCTCGTCGGACTCGGGCTCGCGTTGGAACTCCTCGTAGGAGCGATGAGGACCGTCCGACACGCGCCCCATCTCGCTGGCCTCAATGCGTTGGAACTCCTCGTAGGAGCGATGAAGACC

>CP025990|19|15|3490633-3490926|PILER-CR
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GAAACCGCACTTCAGGTCGCCGCGTACAGGTACGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	ACAACGCCGACCACATCCACCTGGCCGCGATCCTGCT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCGGGCTGGCGGAAGTCGCGGCGCAGCGCGAACCAGA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCCCTCCCCGCCGTCCTCGTCGGACTCGGGCTCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

>CP025990|19|18|3490633-3490993|CRISPRCasFinder
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GAAACCGCACTTCAGGTCGCCGCGTACAGGTACGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	ACAACGCCGACCACATCCACCTGGCCGCGATCCTGCT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCGGGCTGGCGGAAGTCGCGGCGCAGCGCGAACCAGA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCCCTCCCCGCCGTCCTCGTCGGACTCGGGCTCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CGTCCGACACGCGCCCCATCTCGCTGGCCTCAATGC
GTTGGAACTCCTCGTAGGAGCGATGAAGACC

>CP025990|19|15|3490633-3490992|CRT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GAAACCGCACTTCAGGTCGCCGCGTACAGGTACGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	ACAACGCCGACCACATCCACCTGGCCGCGATCCTGCT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCGGGCTGGCGGAAGTCGCGGCGCAGCGCGAACCAGA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCCCTCCCCGCCGTCCTCGTCGGACTCGGGCTCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CGTCCGACACGCGCCCCATCTCGCTGGCCTCAATGC
GTTGGAACTCCTCGTAGGAGCGATGAAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	unknown	unknown	gnl|CDD|226425
CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase	unknown	unknown	unknown
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	unknown	unknown	gnl|CDD|380463
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	unknown	unknown	gnl|CDD|226607
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	unknown	unknown	gnl|CDD|378935
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	unknown	unknown	gnl|CDD|377550
CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	unknown	unknown	gnl|CDD|379057
CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	unknown	unknown	gnl|CDD|223943
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	unknown	unknown	gnl|CDD|369438
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	unknown	unknown	gnl|CDD|379414
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	unknown	unknown	gnl|CDD|379504

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.08071e-14
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	gnl|CDD|380463	cd19540, LCL_NRPS-like, LCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs) and similar domains. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	9.56636e-56
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.53334e-30
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.34402e-14
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.27895e-07
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	gnl|CDD|377550	pfam05711, TylF, Macrocin-O-methyltransferase (TylF). This family consists of bacterial macrocin O-methyltransferase (TylF) proteins. TylF is responsible for the methylation of macrocin to produce tylosin. Tylosin is a macrolide antibiotic used in veterinary medicine to treat infections caused by Gram-positive bacteria and as an animal growth promoter in the swine industry. It is produced by several Streptomyces species. As with other macrolides, the antibiotic activity of tylosin is due to the inhibition of protein biosynthesis by a mechanism that involves the binding of tylosin to the ribosome, preventing the formation of the mRNA-aminoacyl-tRNA-ribosome complex. The structure of one representative sequence from this family, NovP, shows it to be an S-adenosyl-l-methionine-dependent O-methyltransferase that catalyzes the penultimate step in the biosynthesis of the aminocoumarin antibiotic novobiocin. Specifically, it methylates at 4-OH of the noviose moiety, and the resultant methoxy group is important for the potency of the mature antibiotic. It is likely that the key structural features of NovP are common to the rest of the family and include: a helical 'lid' region that gates access to the co-substrate binding pocket and an active centre that contains a 3-Asp putative metal binding site. A further conserved Asp probably acts as the general base that initiates the reaction by de-protonating the 4-OH group of the noviose unit.	1.14175e-129
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	gnl|CDD|379057	pfam13186, SPASM, Iron-sulfur cluster-binding domain. This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many radical SAM domain, pfam04055 proteins. The domain occurs in a number of proteins that modify a protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.	0.000130476
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	gnl|CDD|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	3.49919e-58
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	2.24119e-17
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	6.71984e-17
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	4.31218e-17
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	gnl|CDD|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	4.53447e-45
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	gnl|CDD|379504	pfam14206, Cys_rich_CPCC, Cysteine-rich CPCC. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 68 and 104 amino acids in length. There are six conserved cysteines and a conserved CPCC sequence motif.	2.03318e-24

Protein sequences

>CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein
MVSTSRTSHDDHEQVHTVLLARERAIRDKDVLASSSVYVPDVTVFALAPPLSLRGQAAFDEAGTRAWYDSFTGPIGRQRRDLVVEVSGDVACAHCLVHLTGRRTDGVETDLWFRETLVLRRHDDTWLISHEHASVPLLMDGSGAAATQLHP
>CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein
MADLQAVVFDWRGTLVTTLNSEQWVREALRLLGRDQGAASVAAVHGAIERAAGNPNRLEAAGVDSDKGLHHDTYYSVFSEAGLDAELADALYTVESDPAYNHFADDVAETLHAVSARGCGVAILSDIHFDLRPVFAEAGLDRFVNAFVLSFERGMQKPQLAMFRSALDELGTEPRRTLMVGDRASYDGVAVELGMPTMLVPPLTDARQRRLHHVRNLVGSVPTSS
>CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase
MTLPCRRTRRGTGPDPRCLGGAPGAGTRTNHEGRVAVIARQNTSHSSAPDTSETGAALYLDLLERVVTNLIYEDDGIPNRYLPDGRFDLDRRQNGIDWPSVAHTMVGLKRVRNVRYCLERVLAEGVPGDFIETGVWRGGVCVFARGVLKAYGCTDRAVWVADSFQGIPDTGPDGHHLDRALALHEANHVLGVPLDVVRRNFQQYGLLDDQVRFLPGWFRDTLPTAPMERLAVLRLDGDLYESTTDALTNLYPKLSPGGFVIIDDFVIEACAQAVHDFRQRAGVEEPLVAIDDGGVYWRREN
>CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase
MNSLTDPRVADVIARLHQEAEAADQPVLEDRPGGAMADEDLIRRTLEEEARDYRSLYHRYADNYFSVSPTFGQFLYVCARTTRSRLVIEYGTSFGVSTLYLAAALRDNGAGHLVTTELEPAKAARAQENLAEAGLADLVDVRVGDALDTLRAEPAEPVDLLLLDGAFSLYLPVLRLVEPYLRPGALVVAENAIEAVSDYRDHVRAPHNGYLTLTVPFDETRGNELSLRTG
>CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein
MDGTRSLSSSRRTFSFPCRQTCADGAVSTGELIFTEFDEKRPFRRAGHALVGRREHLRAVRTALAAVAAGDEAVILVEGGAGTGKSALLRAAGSSAHGLGLPVLPVSASSYEADEPLGLARRICEAAGTEPPALVDDIPEARRVVLERVTAWARGAPALLAIDDFQWCDAASLRCLSFLLRRGVRGLGVLASLTTGVSGADPVLVDEAQRSHPRPVRVRLGPLGRAEADRLVAGVLGPVPADLRAALFEWTGGNPFLLDEVLTELPGHPRGQVTDIVPRTVYPWLSGLLANGNPVCLPVVRALAALGDHASPTVLGEVAGLSALEVDYGIRALAELSLLRPGPRPAFAHPVVEAAVARQITPHELVRLRLVGARWLVTTGAPETSVISYLVDSGVADHPEGAELVVATARGMVDRSPPEEAVARLRDALSRRLPLPVRTELLQLCARAELDLDVGLAERRLGEAVVLLGCSRRPAVLVDHARALHALGRLDEAARLLCSVDAETPAGERDPALRDRVRLELATIVAGDPAVAMAPTSDPRDAVAAVVHLLVDGGVRGAPRHGLALGDLWDLLTPAAPDGLPLTWFTAVRALLSAGEGAGLLSYARLWVSAARQGTLRLALGHAQLAEALFRLDRIRCAGAAVNDVLRQWETLDHPGGCLPIIAAMPPVLDTLIERDELDSAVELLRQLPLNPDRRPHWHQLALLLRRGRLRRLLGDPAGGLSDLVRCGRVLRERGSRVPHPLRWRRHATVALLDLGRLDAARRLIDVELSDVRRRSPVGNELGVTLRLAGRVAGPSVGLGLLSQSVEVLEAGGSRVELARSLGELGTALSRMGRSRAARSRLRRACGLAEETGAVRLRACLEARLRDAGGRVRKQVTGVGALTAGERRVARLAATGHTNRQIAAELFITRRAVEMHLTQVYRKLGISGRGQLARALDDADDPVVRHGVVPAGR
>CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein
MHQTVIVGGNVRPSHAARRLQRQVQFAGQGRLHHLVPSGPGREGPAQCLLGGNRALVARLPLGSLDVQAHLHQTIFRLEPPQINAGINPELVVSVGVRRRPRDGSQGECVTVLERSQLSASGPGEQPNDPIASEDFSYLTGVSIPVDGGVAAGRPLRLPAL
>CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein
MTRRSRAGPLVLTRPLFLAAAAPQLSLAAYAHQDLPFERLVEVLNPTRSLSRHPLFQVMIAFQTTTGTVFDLPGLDARLEPDASRIAKFDLTCGLHERRGEDGGPAGISGALEYATDLFDEPTAASFADRLVRLLTDLVTGPDQALSSWDLLGSSERELVVRGWNDTELAVPPVSVAGFVHPGAPRWSYSSAGC
>CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein
MGGGAAGGGGGMAGGGARGRGGQGEDDGEHKRADYLLETDDVFGDGRLVAPSVLGDQPPTGR
>CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein
MTVSPRGRITLPAIAVDVIQTRLRATLPAALKTVGFGSTEDERRMLHQRAWQELEARGLVRTGDLDPFLEDAFQILARPPLAVWALLQTDRENGIDAVIAASGDFAVLAMQSGPENAPREEKELVLEAVRPTGLAHVAASLLPEHRPGKGQSVSCPSDLIEKATANASPGPGGLRASLTSHGMRPGEAEFIAEVLTSERLRYGEFSTRSFNRLAGKTTRSAYRVDVLDTSIGRYLLQHKPDGQGRPWFAMAPTDRTRMAGRIQELITSVTT
>CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein
MYFTDRGIEELEDRRGDEEVSFGYLADRLRAFVDENPRFEDAVERLATYLARDDGDEDAD
>CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein
MDRAVDRVRTWRRERDEATALLRSAGCRVNSFVPGTLVLLADGTHKPIEDNQLGDEVLASDPDTGEIGPQRVVATITNEGPKTLVDVSHTPSPDHLPDTVTDEHPFWVNNHGHWIHATDLTRGDTLLTPTGDHTTITHAHSYPHHHRVHNLTTNTIHTYYVLAGATPVLVHNATPEENCDLTLGAGPNAPEGVAFVDGNIDVSGGRELIEKSGQAHGCHTCSFRSPNTPNGRWIPDHQPPSSLVPPGSP
>CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein
MNLYPCPCCGYLVHNFPPGSHCICPICDWEDDLVQLRWPDISGANQVPLTESQLIYKDIGIADSNSTSKIRPLADFWSIDFGFRTIDEKIHNFEPNGAIEANWPEDRTRLYWWRPNFWRRLHKSP
>CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein
MSPRVVYQHVTHTIRHTPEGGITYEAFRVAANCGAESGPHAEQEAAQDWALRHTGRTGHDLFRRVFTGHAKVTRAE
>CP025990.1|AUS79460.1|3498163_3498349_+|excisionase
MRGDELLTVPEAMARLKIGRSALYDLLRTRRLASLTISRARRIPAHALDDYVQRHLEQASR
>CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein
MDIEQLMEKLGRSGVTVILKVDDERMAEGGEPWTLVMSGPGLGPEGFIRAESSSLSDCLEQGFNRLRSRPGDWEWLAEIS
>CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein
MAVAADGTVWPCVFSRWLPVGNVRVAPLAEILTGPTMLKTTTVLAAHFSARPSNPCVPNMCDPQCGPSCSPACVPANNCAPVGACVPSEY
>CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter
MLARRAYIPDELLSSEVADSWPLTVPCVAQLAEQGMVFDKPITFLVGENGSGKSTLVEAFAEAWGLDARGGRAGRKYVNDRPKTALGELIRWETTSAGARHKSGTRTKRRGYFLRAETAFGFMEAVSGMRGYWEEDTSEMSHGEGFLTVLANMFREPGFYLMDEPEAALSFKSCLRLVNLLYDLGQSGAQVICATHSPVLAATPGADIIEVGDDGFQRIEWEDLDLVDHWRRYMNNPTAYLRYITDE
>CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase
MVVDTSEADARFRQWMHGNLDRAAERFGVVVIGEPLLGWLDRSISAPVRKGGADYWLRVVSEDKQWIGGDFWTGNVDANVVTGLAKPRVLDVFEWEEWRQQRAEIMTRLPGSPCSPTDALRAEVDLADEWWTELRHTVDVIATTPTERVNSTQDKVADRIVHRFGDAVDPAVPAWETVHGDVHWANLFGPRFGLLDWELWGRGPVGTDAATLLCYSLLVPTIAQRVHKVFADVLDTEAGRFAQLYVIARLSRRTDSGEFPDLAGPLERRARALLNP
>CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein
MGALLLAAALVLASCSTEDASEPDTTDATTESTAAPSLTEEFPRETELLAPPVSTPLDATDIEPCALISDQEVSAMGYDAGSARTGFENSCTWDSTEHEGSRATLRANTEDGGLSWIYQIRDRYGVFDEMMVGEYPAVHAHTIEDESRCVLYTGIADDQYLNTNFVRNTLDDFDACQAAIEFTEAVIAELPAAS
>CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein
MSGSYEVDPEALPRAIAELKEAREVVAELEDRGIAISAKRSTRGDDGVSMNAGDQLARLGGDPGEGSLAATAAKLRAELDNTIFAFEEMLREYLELEQSATLPEYDGEVSQVSLPPDYWERQALNNGRRSGGDYVAI

Crispr_ID: CP025990_20

• CRISPR_ID: CP025990_20
• CRISPR_location: 3491195-3491357
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP025990_20

Consensus_repeat	Method
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder

spacers of CP025990_20

>20.1|3491225|37|CP025990|CRISPRCasFinder
CGGCCGCTGTGACCGCAGACCAGCGCATCGCCGAAAT
>20.2|3491292|35|CP025990|CRISPRCasFinder
AAGCTCCGCCGGAACGAAGAGGCGGGTCAGCTCAC

CRISPR arrays and Neighbor proteins around CP025990_20

CRISPR arrays

The CRISPR arrays of CP025990_20

>merge|CP025990|20|3491195-3491357|CRISPRCasFinder
GTAGGAACTCCTCGTAGGAGCGATGAGGACCGGCCGCTGTGACCGCAGACCAGCGCATCGCCGAAATGTTGGAACTCCTCGTAGGAGCGATGAGGACAAGCTCCGCCGGAACGAAGAGGCGGGTCAGCTCACGTTGGAACTCCTCGTAGGAGCGATGAGGACC

>CP025990|20|19|3491195-3491357|CRISPRCasFinder
GTAGGAACTCCTCGTAGGAGCGATGAGGAC	CGGCCGCTGTGACCGCAGACCAGCGCATCGCCGAAAT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	AAGCTCCGCCGGAACGAAGAGGCGGGTCAGCTCAC
GTTGGAACTCCTCGTAGGAGCGATGAGGACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	unknown	unknown	gnl|CDD|226425
CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase	unknown	unknown	unknown
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	unknown	unknown	gnl|CDD|380463
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	unknown	unknown	gnl|CDD|226607
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	unknown	unknown	gnl|CDD|378935
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	unknown	unknown	gnl|CDD|377550
CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	unknown	unknown	gnl|CDD|379057
CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	unknown	unknown	gnl|CDD|223943
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	unknown	unknown	gnl|CDD|369438
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	unknown	unknown	gnl|CDD|379414
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	unknown	unknown	gnl|CDD|379504

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.08071e-14
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	gnl|CDD|380463	cd19540, LCL_NRPS-like, LCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs) and similar domains. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	9.56636e-56
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.53334e-30
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.34402e-14
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.27895e-07
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	gnl|CDD|377550	pfam05711, TylF, Macrocin-O-methyltransferase (TylF). This family consists of bacterial macrocin O-methyltransferase (TylF) proteins. TylF is responsible for the methylation of macrocin to produce tylosin. Tylosin is a macrolide antibiotic used in veterinary medicine to treat infections caused by Gram-positive bacteria and as an animal growth promoter in the swine industry. It is produced by several Streptomyces species. As with other macrolides, the antibiotic activity of tylosin is due to the inhibition of protein biosynthesis by a mechanism that involves the binding of tylosin to the ribosome, preventing the formation of the mRNA-aminoacyl-tRNA-ribosome complex. The structure of one representative sequence from this family, NovP, shows it to be an S-adenosyl-l-methionine-dependent O-methyltransferase that catalyzes the penultimate step in the biosynthesis of the aminocoumarin antibiotic novobiocin. Specifically, it methylates at 4-OH of the noviose moiety, and the resultant methoxy group is important for the potency of the mature antibiotic. It is likely that the key structural features of NovP are common to the rest of the family and include: a helical 'lid' region that gates access to the co-substrate binding pocket and an active centre that contains a 3-Asp putative metal binding site. A further conserved Asp probably acts as the general base that initiates the reaction by de-protonating the 4-OH group of the noviose unit.	1.14175e-129
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	gnl|CDD|379057	pfam13186, SPASM, Iron-sulfur cluster-binding domain. This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many radical SAM domain, pfam04055 proteins. The domain occurs in a number of proteins that modify a protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.	0.000130476
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	gnl|CDD|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	3.49919e-58
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	2.24119e-17
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	6.71984e-17
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	4.31218e-17
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	gnl|CDD|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	4.53447e-45
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	gnl|CDD|379504	pfam14206, Cys_rich_CPCC, Cysteine-rich CPCC. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 68 and 104 amino acids in length. There are six conserved cysteines and a conserved CPCC sequence motif.	2.03318e-24

Protein sequences

>CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein
MVSTSRTSHDDHEQVHTVLLARERAIRDKDVLASSSVYVPDVTVFALAPPLSLRGQAAFDEAGTRAWYDSFTGPIGRQRRDLVVEVSGDVACAHCLVHLTGRRTDGVETDLWFRETLVLRRHDDTWLISHEHASVPLLMDGSGAAATQLHP
>CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein
MADLQAVVFDWRGTLVTTLNSEQWVREALRLLGRDQGAASVAAVHGAIERAAGNPNRLEAAGVDSDKGLHHDTYYSVFSEAGLDAELADALYTVESDPAYNHFADDVAETLHAVSARGCGVAILSDIHFDLRPVFAEAGLDRFVNAFVLSFERGMQKPQLAMFRSALDELGTEPRRTLMVGDRASYDGVAVELGMPTMLVPPLTDARQRRLHHVRNLVGSVPTSS
>CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase
MTLPCRRTRRGTGPDPRCLGGAPGAGTRTNHEGRVAVIARQNTSHSSAPDTSETGAALYLDLLERVVTNLIYEDDGIPNRYLPDGRFDLDRRQNGIDWPSVAHTMVGLKRVRNVRYCLERVLAEGVPGDFIETGVWRGGVCVFARGVLKAYGCTDRAVWVADSFQGIPDTGPDGHHLDRALALHEANHVLGVPLDVVRRNFQQYGLLDDQVRFLPGWFRDTLPTAPMERLAVLRLDGDLYESTTDALTNLYPKLSPGGFVIIDDFVIEACAQAVHDFRQRAGVEEPLVAIDDGGVYWRREN
>CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase
MNSLTDPRVADVIARLHQEAEAADQPVLEDRPGGAMADEDLIRRTLEEEARDYRSLYHRYADNYFSVSPTFGQFLYVCARTTRSRLVIEYGTSFGVSTLYLAAALRDNGAGHLVTTELEPAKAARAQENLAEAGLADLVDVRVGDALDTLRAEPAEPVDLLLLDGAFSLYLPVLRLVEPYLRPGALVVAENAIEAVSDYRDHVRAPHNGYLTLTVPFDETRGNELSLRTG
>CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein
MDGTRSLSSSRRTFSFPCRQTCADGAVSTGELIFTEFDEKRPFRRAGHALVGRREHLRAVRTALAAVAAGDEAVILVEGGAGTGKSALLRAAGSSAHGLGLPVLPVSASSYEADEPLGLARRICEAAGTEPPALVDDIPEARRVVLERVTAWARGAPALLAIDDFQWCDAASLRCLSFLLRRGVRGLGVLASLTTGVSGADPVLVDEAQRSHPRPVRVRLGPLGRAEADRLVAGVLGPVPADLRAALFEWTGGNPFLLDEVLTELPGHPRGQVTDIVPRTVYPWLSGLLANGNPVCLPVVRALAALGDHASPTVLGEVAGLSALEVDYGIRALAELSLLRPGPRPAFAHPVVEAAVARQITPHELVRLRLVGARWLVTTGAPETSVISYLVDSGVADHPEGAELVVATARGMVDRSPPEEAVARLRDALSRRLPLPVRTELLQLCARAELDLDVGLAERRLGEAVVLLGCSRRPAVLVDHARALHALGRLDEAARLLCSVDAETPAGERDPALRDRVRLELATIVAGDPAVAMAPTSDPRDAVAAVVHLLVDGGVRGAPRHGLALGDLWDLLTPAAPDGLPLTWFTAVRALLSAGEGAGLLSYARLWVSAARQGTLRLALGHAQLAEALFRLDRIRCAGAAVNDVLRQWETLDHPGGCLPIIAAMPPVLDTLIERDELDSAVELLRQLPLNPDRRPHWHQLALLLRRGRLRRLLGDPAGGLSDLVRCGRVLRERGSRVPHPLRWRRHATVALLDLGRLDAARRLIDVELSDVRRRSPVGNELGVTLRLAGRVAGPSVGLGLLSQSVEVLEAGGSRVELARSLGELGTALSRMGRSRAARSRLRRACGLAEETGAVRLRACLEARLRDAGGRVRKQVTGVGALTAGERRVARLAATGHTNRQIAAELFITRRAVEMHLTQVYRKLGISGRGQLARALDDADDPVVRHGVVPAGR
>CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein
MHQTVIVGGNVRPSHAARRLQRQVQFAGQGRLHHLVPSGPGREGPAQCLLGGNRALVARLPLGSLDVQAHLHQTIFRLEPPQINAGINPELVVSVGVRRRPRDGSQGECVTVLERSQLSASGPGEQPNDPIASEDFSYLTGVSIPVDGGVAAGRPLRLPAL
>CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein
MTRRSRAGPLVLTRPLFLAAAAPQLSLAAYAHQDLPFERLVEVLNPTRSLSRHPLFQVMIAFQTTTGTVFDLPGLDARLEPDASRIAKFDLTCGLHERRGEDGGPAGISGALEYATDLFDEPTAASFADRLVRLLTDLVTGPDQALSSWDLLGSSERELVVRGWNDTELAVPPVSVAGFVHPGAPRWSYSSAGC
>CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein
MGGGAAGGGGGMAGGGARGRGGQGEDDGEHKRADYLLETDDVFGDGRLVAPSVLGDQPPTGR
>CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein
MTVSPRGRITLPAIAVDVIQTRLRATLPAALKTVGFGSTEDERRMLHQRAWQELEARGLVRTGDLDPFLEDAFQILARPPLAVWALLQTDRENGIDAVIAASGDFAVLAMQSGPENAPREEKELVLEAVRPTGLAHVAASLLPEHRPGKGQSVSCPSDLIEKATANASPGPGGLRASLTSHGMRPGEAEFIAEVLTSERLRYGEFSTRSFNRLAGKTTRSAYRVDVLDTSIGRYLLQHKPDGQGRPWFAMAPTDRTRMAGRIQELITSVTT
>CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein
MYFTDRGIEELEDRRGDEEVSFGYLADRLRAFVDENPRFEDAVERLATYLARDDGDEDAD
>CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein
MDRAVDRVRTWRRERDEATALLRSAGCRVNSFVPGTLVLLADGTHKPIEDNQLGDEVLASDPDTGEIGPQRVVATITNEGPKTLVDVSHTPSPDHLPDTVTDEHPFWVNNHGHWIHATDLTRGDTLLTPTGDHTTITHAHSYPHHHRVHNLTTNTIHTYYVLAGATPVLVHNATPEENCDLTLGAGPNAPEGVAFVDGNIDVSGGRELIEKSGQAHGCHTCSFRSPNTPNGRWIPDHQPPSSLVPPGSP
>CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein
MNLYPCPCCGYLVHNFPPGSHCICPICDWEDDLVQLRWPDISGANQVPLTESQLIYKDIGIADSNSTSKIRPLADFWSIDFGFRTIDEKIHNFEPNGAIEANWPEDRTRLYWWRPNFWRRLHKSP
>CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein
MSPRVVYQHVTHTIRHTPEGGITYEAFRVAANCGAESGPHAEQEAAQDWALRHTGRTGHDLFRRVFTGHAKVTRAE
>CP025990.1|AUS79460.1|3498163_3498349_+|excisionase
MRGDELLTVPEAMARLKIGRSALYDLLRTRRLASLTISRARRIPAHALDDYVQRHLEQASR
>CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein
MDIEQLMEKLGRSGVTVILKVDDERMAEGGEPWTLVMSGPGLGPEGFIRAESSSLSDCLEQGFNRLRSRPGDWEWLAEIS
>CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein
MAVAADGTVWPCVFSRWLPVGNVRVAPLAEILTGPTMLKTTTVLAAHFSARPSNPCVPNMCDPQCGPSCSPACVPANNCAPVGACVPSEY
>CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter
MLARRAYIPDELLSSEVADSWPLTVPCVAQLAEQGMVFDKPITFLVGENGSGKSTLVEAFAEAWGLDARGGRAGRKYVNDRPKTALGELIRWETTSAGARHKSGTRTKRRGYFLRAETAFGFMEAVSGMRGYWEEDTSEMSHGEGFLTVLANMFREPGFYLMDEPEAALSFKSCLRLVNLLYDLGQSGAQVICATHSPVLAATPGADIIEVGDDGFQRIEWEDLDLVDHWRRYMNNPTAYLRYITDE
>CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase
MVVDTSEADARFRQWMHGNLDRAAERFGVVVIGEPLLGWLDRSISAPVRKGGADYWLRVVSEDKQWIGGDFWTGNVDANVVTGLAKPRVLDVFEWEEWRQQRAEIMTRLPGSPCSPTDALRAEVDLADEWWTELRHTVDVIATTPTERVNSTQDKVADRIVHRFGDAVDPAVPAWETVHGDVHWANLFGPRFGLLDWELWGRGPVGTDAATLLCYSLLVPTIAQRVHKVFADVLDTEAGRFAQLYVIARLSRRTDSGEFPDLAGPLERRARALLNP
>CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein
MGALLLAAALVLASCSTEDASEPDTTDATTESTAAPSLTEEFPRETELLAPPVSTPLDATDIEPCALISDQEVSAMGYDAGSARTGFENSCTWDSTEHEGSRATLRANTEDGGLSWIYQIRDRYGVFDEMMVGEYPAVHAHTIEDESRCVLYTGIADDQYLNTNFVRNTLDDFDACQAAIEFTEAVIAELPAAS
>CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein
MSGSYEVDPEALPRAIAELKEAREVVAELEDRGIAISAKRSTRGDDGVSMNAGDQLARLGGDPGEGSLAATAAKLRAELDNTIFAFEEMLREYLELEQSATLPEYDGEVSQVSLPPDYWERQALNNGRRSGGDYVAI

Crispr_ID: CP025990_23

• CRISPR_ID: CP025990_23
• CRISPR_location: 3492711-3492934
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP025990_23

Consensus_repeat	Method
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder

spacers of CP025990_23

>23.1|3492741|35|CP025990|CRISPRCasFinder
AGCCGGAACACCAGGGCGCGGATCGACTCCTACCA
>23.2|3492806|32|CP025990|CRISPRCasFinder
CGTGCCGACCTCGCATGTCAGGCAGCGAAGAC
>23.3|3492868|37|CP025990|CRISPRCasFinder
CCGAACGCGGAGCTCCGGGTCCTGGGCGCACAAAAGG

CRISPR arrays and Neighbor proteins around CP025990_23

CRISPR arrays

The CRISPR arrays of CP025990_23

>merge|CP025990|23|3492711-3492934|CRISPRCasFinder
GTCGTGACCCCTCTTAGGGGCGATGAGGACAGCCGGAACACCAGGGCGCGGATCGACTCCTACCAGTTGTGACCCCTTTTAGGGGCGATGAGGACCGTGCCGACCTCGCATGTCAGGCAGCGAAGACGTTGTGATTCCTTTAGGGGGCGATGAGGACCCGAACGCGGAGCTCCGGGTCCTGGGCGCACAAAAGGGTTGTGACCCCTCTTAGGGGCGATGAGGAC

>CP025990|23|22|3492711-3492934|CRISPRCasFinder
GTCGTGACCCCTCTTAGGGGCGATGAGGAC	AGCCGGAACACCAGGGCGCGGATCGACTCCTACCA
GTTGTGACCCCTTTTAGGGGCGATGAGGAC	CGTGCCGACCTCGCATGTCAGGCAGCGAAGAC
GTTGTGATTCCTTTAGGGGGCGATGAGGAC	CCGAACGCGGAGCTCCGGGTCCTGGGCGCACAAAAGG
GTTGTGACCCCTCTTAGGGGCGATGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	unknown	unknown	gnl|CDD|226425
CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase	unknown	unknown	unknown
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	unknown	unknown	gnl|CDD|380463
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	unknown	unknown	gnl|CDD|226607
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	unknown	unknown	gnl|CDD|378935
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	unknown	unknown	gnl|CDD|377550
CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	unknown	unknown	gnl|CDD|379057
CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	unknown	unknown	gnl|CDD|223943
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	unknown	unknown	gnl|CDD|369438
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	unknown	unknown	gnl|CDD|379414
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	unknown	unknown	gnl|CDD|379504

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.08071e-14
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	gnl|CDD|380463	cd19540, LCL_NRPS-like, LCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs) and similar domains. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	9.56636e-56
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.53334e-30
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.34402e-14
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.27895e-07
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	gnl|CDD|377550	pfam05711, TylF, Macrocin-O-methyltransferase (TylF). This family consists of bacterial macrocin O-methyltransferase (TylF) proteins. TylF is responsible for the methylation of macrocin to produce tylosin. Tylosin is a macrolide antibiotic used in veterinary medicine to treat infections caused by Gram-positive bacteria and as an animal growth promoter in the swine industry. It is produced by several Streptomyces species. As with other macrolides, the antibiotic activity of tylosin is due to the inhibition of protein biosynthesis by a mechanism that involves the binding of tylosin to the ribosome, preventing the formation of the mRNA-aminoacyl-tRNA-ribosome complex. The structure of one representative sequence from this family, NovP, shows it to be an S-adenosyl-l-methionine-dependent O-methyltransferase that catalyzes the penultimate step in the biosynthesis of the aminocoumarin antibiotic novobiocin. Specifically, it methylates at 4-OH of the noviose moiety, and the resultant methoxy group is important for the potency of the mature antibiotic. It is likely that the key structural features of NovP are common to the rest of the family and include: a helical 'lid' region that gates access to the co-substrate binding pocket and an active centre that contains a 3-Asp putative metal binding site. A further conserved Asp probably acts as the general base that initiates the reaction by de-protonating the 4-OH group of the noviose unit.	1.14175e-129
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	gnl|CDD|379057	pfam13186, SPASM, Iron-sulfur cluster-binding domain. This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many radical SAM domain, pfam04055 proteins. The domain occurs in a number of proteins that modify a protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.	0.000130476
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	gnl|CDD|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	3.49919e-58
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	2.24119e-17
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	6.71984e-17
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	4.31218e-17
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	gnl|CDD|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	4.53447e-45
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	gnl|CDD|379504	pfam14206, Cys_rich_CPCC, Cysteine-rich CPCC. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 68 and 104 amino acids in length. There are six conserved cysteines and a conserved CPCC sequence motif.	2.03318e-24

Protein sequences

>CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein
MVSTSRTSHDDHEQVHTVLLARERAIRDKDVLASSSVYVPDVTVFALAPPLSLRGQAAFDEAGTRAWYDSFTGPIGRQRRDLVVEVSGDVACAHCLVHLTGRRTDGVETDLWFRETLVLRRHDDTWLISHEHASVPLLMDGSGAAATQLHP
>CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein
MADLQAVVFDWRGTLVTTLNSEQWVREALRLLGRDQGAASVAAVHGAIERAAGNPNRLEAAGVDSDKGLHHDTYYSVFSEAGLDAELADALYTVESDPAYNHFADDVAETLHAVSARGCGVAILSDIHFDLRPVFAEAGLDRFVNAFVLSFERGMQKPQLAMFRSALDELGTEPRRTLMVGDRASYDGVAVELGMPTMLVPPLTDARQRRLHHVRNLVGSVPTSS
>CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase
MTLPCRRTRRGTGPDPRCLGGAPGAGTRTNHEGRVAVIARQNTSHSSAPDTSETGAALYLDLLERVVTNLIYEDDGIPNRYLPDGRFDLDRRQNGIDWPSVAHTMVGLKRVRNVRYCLERVLAEGVPGDFIETGVWRGGVCVFARGVLKAYGCTDRAVWVADSFQGIPDTGPDGHHLDRALALHEANHVLGVPLDVVRRNFQQYGLLDDQVRFLPGWFRDTLPTAPMERLAVLRLDGDLYESTTDALTNLYPKLSPGGFVIIDDFVIEACAQAVHDFRQRAGVEEPLVAIDDGGVYWRREN
>CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase
MNSLTDPRVADVIARLHQEAEAADQPVLEDRPGGAMADEDLIRRTLEEEARDYRSLYHRYADNYFSVSPTFGQFLYVCARTTRSRLVIEYGTSFGVSTLYLAAALRDNGAGHLVTTELEPAKAARAQENLAEAGLADLVDVRVGDALDTLRAEPAEPVDLLLLDGAFSLYLPVLRLVEPYLRPGALVVAENAIEAVSDYRDHVRAPHNGYLTLTVPFDETRGNELSLRTG
>CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein
MDGTRSLSSSRRTFSFPCRQTCADGAVSTGELIFTEFDEKRPFRRAGHALVGRREHLRAVRTALAAVAAGDEAVILVEGGAGTGKSALLRAAGSSAHGLGLPVLPVSASSYEADEPLGLARRICEAAGTEPPALVDDIPEARRVVLERVTAWARGAPALLAIDDFQWCDAASLRCLSFLLRRGVRGLGVLASLTTGVSGADPVLVDEAQRSHPRPVRVRLGPLGRAEADRLVAGVLGPVPADLRAALFEWTGGNPFLLDEVLTELPGHPRGQVTDIVPRTVYPWLSGLLANGNPVCLPVVRALAALGDHASPTVLGEVAGLSALEVDYGIRALAELSLLRPGPRPAFAHPVVEAAVARQITPHELVRLRLVGARWLVTTGAPETSVISYLVDSGVADHPEGAELVVATARGMVDRSPPEEAVARLRDALSRRLPLPVRTELLQLCARAELDLDVGLAERRLGEAVVLLGCSRRPAVLVDHARALHALGRLDEAARLLCSVDAETPAGERDPALRDRVRLELATIVAGDPAVAMAPTSDPRDAVAAVVHLLVDGGVRGAPRHGLALGDLWDLLTPAAPDGLPLTWFTAVRALLSAGEGAGLLSYARLWVSAARQGTLRLALGHAQLAEALFRLDRIRCAGAAVNDVLRQWETLDHPGGCLPIIAAMPPVLDTLIERDELDSAVELLRQLPLNPDRRPHWHQLALLLRRGRLRRLLGDPAGGLSDLVRCGRVLRERGSRVPHPLRWRRHATVALLDLGRLDAARRLIDVELSDVRRRSPVGNELGVTLRLAGRVAGPSVGLGLLSQSVEVLEAGGSRVELARSLGELGTALSRMGRSRAARSRLRRACGLAEETGAVRLRACLEARLRDAGGRVRKQVTGVGALTAGERRVARLAATGHTNRQIAAELFITRRAVEMHLTQVYRKLGISGRGQLARALDDADDPVVRHGVVPAGR
>CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein
MHQTVIVGGNVRPSHAARRLQRQVQFAGQGRLHHLVPSGPGREGPAQCLLGGNRALVARLPLGSLDVQAHLHQTIFRLEPPQINAGINPELVVSVGVRRRPRDGSQGECVTVLERSQLSASGPGEQPNDPIASEDFSYLTGVSIPVDGGVAAGRPLRLPAL
>CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein
MTRRSRAGPLVLTRPLFLAAAAPQLSLAAYAHQDLPFERLVEVLNPTRSLSRHPLFQVMIAFQTTTGTVFDLPGLDARLEPDASRIAKFDLTCGLHERRGEDGGPAGISGALEYATDLFDEPTAASFADRLVRLLTDLVTGPDQALSSWDLLGSSERELVVRGWNDTELAVPPVSVAGFVHPGAPRWSYSSAGC
>CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein
MGGGAAGGGGGMAGGGARGRGGQGEDDGEHKRADYLLETDDVFGDGRLVAPSVLGDQPPTGR
>CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein
MTVSPRGRITLPAIAVDVIQTRLRATLPAALKTVGFGSTEDERRMLHQRAWQELEARGLVRTGDLDPFLEDAFQILARPPLAVWALLQTDRENGIDAVIAASGDFAVLAMQSGPENAPREEKELVLEAVRPTGLAHVAASLLPEHRPGKGQSVSCPSDLIEKATANASPGPGGLRASLTSHGMRPGEAEFIAEVLTSERLRYGEFSTRSFNRLAGKTTRSAYRVDVLDTSIGRYLLQHKPDGQGRPWFAMAPTDRTRMAGRIQELITSVTT
>CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein
MYFTDRGIEELEDRRGDEEVSFGYLADRLRAFVDENPRFEDAVERLATYLARDDGDEDAD
>CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein
MDRAVDRVRTWRRERDEATALLRSAGCRVNSFVPGTLVLLADGTHKPIEDNQLGDEVLASDPDTGEIGPQRVVATITNEGPKTLVDVSHTPSPDHLPDTVTDEHPFWVNNHGHWIHATDLTRGDTLLTPTGDHTTITHAHSYPHHHRVHNLTTNTIHTYYVLAGATPVLVHNATPEENCDLTLGAGPNAPEGVAFVDGNIDVSGGRELIEKSGQAHGCHTCSFRSPNTPNGRWIPDHQPPSSLVPPGSP
>CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein
MNLYPCPCCGYLVHNFPPGSHCICPICDWEDDLVQLRWPDISGANQVPLTESQLIYKDIGIADSNSTSKIRPLADFWSIDFGFRTIDEKIHNFEPNGAIEANWPEDRTRLYWWRPNFWRRLHKSP
>CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein
MSPRVVYQHVTHTIRHTPEGGITYEAFRVAANCGAESGPHAEQEAAQDWALRHTGRTGHDLFRRVFTGHAKVTRAE
>CP025990.1|AUS79460.1|3498163_3498349_+|excisionase
MRGDELLTVPEAMARLKIGRSALYDLLRTRRLASLTISRARRIPAHALDDYVQRHLEQASR
>CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein
MDIEQLMEKLGRSGVTVILKVDDERMAEGGEPWTLVMSGPGLGPEGFIRAESSSLSDCLEQGFNRLRSRPGDWEWLAEIS
>CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein
MAVAADGTVWPCVFSRWLPVGNVRVAPLAEILTGPTMLKTTTVLAAHFSARPSNPCVPNMCDPQCGPSCSPACVPANNCAPVGACVPSEY
>CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter
MLARRAYIPDELLSSEVADSWPLTVPCVAQLAEQGMVFDKPITFLVGENGSGKSTLVEAFAEAWGLDARGGRAGRKYVNDRPKTALGELIRWETTSAGARHKSGTRTKRRGYFLRAETAFGFMEAVSGMRGYWEEDTSEMSHGEGFLTVLANMFREPGFYLMDEPEAALSFKSCLRLVNLLYDLGQSGAQVICATHSPVLAATPGADIIEVGDDGFQRIEWEDLDLVDHWRRYMNNPTAYLRYITDE
>CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase
MVVDTSEADARFRQWMHGNLDRAAERFGVVVIGEPLLGWLDRSISAPVRKGGADYWLRVVSEDKQWIGGDFWTGNVDANVVTGLAKPRVLDVFEWEEWRQQRAEIMTRLPGSPCSPTDALRAEVDLADEWWTELRHTVDVIATTPTERVNSTQDKVADRIVHRFGDAVDPAVPAWETVHGDVHWANLFGPRFGLLDWELWGRGPVGTDAATLLCYSLLVPTIAQRVHKVFADVLDTEAGRFAQLYVIARLSRRTDSGEFPDLAGPLERRARALLNP
>CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein
MGALLLAAALVLASCSTEDASEPDTTDATTESTAAPSLTEEFPRETELLAPPVSTPLDATDIEPCALISDQEVSAMGYDAGSARTGFENSCTWDSTEHEGSRATLRANTEDGGLSWIYQIRDRYGVFDEMMVGEYPAVHAHTIEDESRCVLYTGIADDQYLNTNFVRNTLDDFDACQAAIEFTEAVIAELPAAS
>CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein
MSGSYEVDPEALPRAIAELKEAREVVAELEDRGIAISAKRSTRGDDGVSMNAGDQLARLGGDPGEGSLAATAAKLRAELDNTIFAFEEMLREYLELEQSATLPEYDGEVSQVSLPPDYWERQALNNGRRSGGDYVAI

Crispr_ID: CP025990_21

• CRISPR_ID: CP025990_21
• CRISPR_location: 3491554-3491848
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP025990_21

Consensus_repeat	Method
GGTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder
GTCCTCATCGCTCCTACGAGGAGTTCCAACC	PILER-CR

spacers of CP025990_21

>21.1|3491585|33|CP025990|CRT
GCCGCGCCCAGCGGAGGGGATGGACCTACCGCC
>21.2|3491649|36|CP025990|CRT,PILER-CR
AAGGCCGTGACACCACCCACGGGACCGAAGACCCAC
>21.3|3491716|35|CP025990|CRT,PILER-CR
ACGCACGTCACCGCGACAGGCCGCCCAGCACAGGA
>21.4|3491782|35|CP025990|CRT
TCCCGGGCCTGCTTCAGGTCCCCTCGTACGCGGCC
>21.5|3491585|34|CP025990|CRISPRCasFinder
GCCGCGCCCAGCGGAGGGGATGGACCTACCGCCG
>21.6|3491649|37|CP025990|CRISPRCasFinder
AAGGCCGTGACACCACCCACGGGACCGAAGACCCACG
>21.7|3491716|36|CP025990|CRISPRCasFinder
ACGCACGTCACCGCGACAGGCCGCCCAGCACAGGAG
>21.8|3491782|36|CP025990|CRISPRCasFinder
TCCCGGGCCTGCTTCAGGTCCCCTCGTACGCGGCCG

CRISPR arrays and Neighbor proteins around CP025990_21

CRISPR arrays

The CRISPR arrays of CP025990_21

>merge|CP025990|21|3491554-3491848|CRT,CRISPRCasFinder,PILER-CR
CGCAGGAACTCCTCCTAGGAGCGATGAGGACGCCGCGCCCAGCGGAGGGGATGGACCTACCGCCGGTTGGAGTTCCTCGTAGGAGCGATGAGGACAAGGCCGTGACACCACCCACGGGACCGAAGACCCACGGTTGGGACTCCTCGTAGGAGCGATGAGGACACGCACGTCACCGCGACAGGCCGCCCAGCACAGGAGGTTGGAACTCCTCGTAGGAGCGATGAGGACTCCCGGGCCTGCTTCAGGTCCCCTCGTACGCGGCCGGTTGGAACTCCTCGTAGGAGCGATGAGGACC

>CP025990|21|16|3491554-3491847|CRT
CGCAGGAACTCCTCCTAGGAGCGATGAGGAC	GCCGCGCCCAGCGGAGGGGATGGACCTACCGCC
GGTTGGAGTTCCTCGTAGGAGCGATGAGGAC	AAGGCCGTGACACCACCCACGGGACCGAAGACCCAC
GGTTGGGACTCCTCGTAGGAGCGATGAGGAC	ACGCACGTCACCGCGACAGGCCGCCCAGCACAGGA
GGTTGGAACTCCTCGTAGGAGCGATGAGGAC	TCCCGGGCCTGCTTCAGGTCCCCTCGTACGCGGCC
GGTTGGAACTCCTCGTAGGAGCGATGAGGAC

>CP025990|21|20|3491555-3491848|CRISPRCasFinder
GCAGGAACTCCTCCTAGGAGCGATGAGGAC	GCCGCGCCCAGCGGAGGGGATGGACCTACCGCCG
GTTGGAGTTCCTCGTAGGAGCGATGAGGAC	AAGGCCGTGACACCACCCACGGGACCGAAGACCCACG
GTTGGGACTCCTCGTAGGAGCGATGAGGAC	ACGCACGTCACCGCGACAGGCCGCCCAGCACAGGAG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	TCCCGGGCCTGCTTCAGGTCCCCTCGTACGCGGCCG
GTTGGAACTCCTCGTAGGAGCGATGAGGACC

>CP025990|21|16|3491618-3491781|PILER-CR
GGTTGGAGTTCCTCGTAGGAGCGATGAGGAC	AAGGCCGTGACACCACCCACGGGACCGAAGACCCAC
GGTTGGGACTCCTCGTAGGAGCGATGAGGAC	ACGCACGTCACCGCGACAGGCCGCCCAGCACAGGA
GGTTGGAACTCCTCGTAGGAGCGATGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	unknown	unknown	gnl|CDD|226425
CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase	unknown	unknown	unknown
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	unknown	unknown	gnl|CDD|380463
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	unknown	unknown	gnl|CDD|226607
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	unknown	unknown	gnl|CDD|378935
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	unknown	unknown	gnl|CDD|377550
CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	unknown	unknown	gnl|CDD|379057
CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	unknown	unknown	gnl|CDD|223943
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	unknown	unknown	gnl|CDD|369438
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	unknown	unknown	gnl|CDD|379414
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	unknown	unknown	gnl|CDD|379504

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.08071e-14
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	gnl|CDD|380463	cd19540, LCL_NRPS-like, LCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs) and similar domains. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	9.56636e-56
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.53334e-30
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.34402e-14
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.27895e-07
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	gnl|CDD|377550	pfam05711, TylF, Macrocin-O-methyltransferase (TylF). This family consists of bacterial macrocin O-methyltransferase (TylF) proteins. TylF is responsible for the methylation of macrocin to produce tylosin. Tylosin is a macrolide antibiotic used in veterinary medicine to treat infections caused by Gram-positive bacteria and as an animal growth promoter in the swine industry. It is produced by several Streptomyces species. As with other macrolides, the antibiotic activity of tylosin is due to the inhibition of protein biosynthesis by a mechanism that involves the binding of tylosin to the ribosome, preventing the formation of the mRNA-aminoacyl-tRNA-ribosome complex. The structure of one representative sequence from this family, NovP, shows it to be an S-adenosyl-l-methionine-dependent O-methyltransferase that catalyzes the penultimate step in the biosynthesis of the aminocoumarin antibiotic novobiocin. Specifically, it methylates at 4-OH of the noviose moiety, and the resultant methoxy group is important for the potency of the mature antibiotic. It is likely that the key structural features of NovP are common to the rest of the family and include: a helical 'lid' region that gates access to the co-substrate binding pocket and an active centre that contains a 3-Asp putative metal binding site. A further conserved Asp probably acts as the general base that initiates the reaction by de-protonating the 4-OH group of the noviose unit.	1.14175e-129
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	gnl|CDD|379057	pfam13186, SPASM, Iron-sulfur cluster-binding domain. This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many radical SAM domain, pfam04055 proteins. The domain occurs in a number of proteins that modify a protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.	0.000130476
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	gnl|CDD|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	3.49919e-58
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	2.24119e-17
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	6.71984e-17
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	4.31218e-17
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	gnl|CDD|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	4.53447e-45
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	gnl|CDD|379504	pfam14206, Cys_rich_CPCC, Cysteine-rich CPCC. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 68 and 104 amino acids in length. There are six conserved cysteines and a conserved CPCC sequence motif.	2.03318e-24

Protein sequences

>CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein
MVSTSRTSHDDHEQVHTVLLARERAIRDKDVLASSSVYVPDVTVFALAPPLSLRGQAAFDEAGTRAWYDSFTGPIGRQRRDLVVEVSGDVACAHCLVHLTGRRTDGVETDLWFRETLVLRRHDDTWLISHEHASVPLLMDGSGAAATQLHP
>CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein
MADLQAVVFDWRGTLVTTLNSEQWVREALRLLGRDQGAASVAAVHGAIERAAGNPNRLEAAGVDSDKGLHHDTYYSVFSEAGLDAELADALYTVESDPAYNHFADDVAETLHAVSARGCGVAILSDIHFDLRPVFAEAGLDRFVNAFVLSFERGMQKPQLAMFRSALDELGTEPRRTLMVGDRASYDGVAVELGMPTMLVPPLTDARQRRLHHVRNLVGSVPTSS
>CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase
MTLPCRRTRRGTGPDPRCLGGAPGAGTRTNHEGRVAVIARQNTSHSSAPDTSETGAALYLDLLERVVTNLIYEDDGIPNRYLPDGRFDLDRRQNGIDWPSVAHTMVGLKRVRNVRYCLERVLAEGVPGDFIETGVWRGGVCVFARGVLKAYGCTDRAVWVADSFQGIPDTGPDGHHLDRALALHEANHVLGVPLDVVRRNFQQYGLLDDQVRFLPGWFRDTLPTAPMERLAVLRLDGDLYESTTDALTNLYPKLSPGGFVIIDDFVIEACAQAVHDFRQRAGVEEPLVAIDDGGVYWRREN
>CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase
MNSLTDPRVADVIARLHQEAEAADQPVLEDRPGGAMADEDLIRRTLEEEARDYRSLYHRYADNYFSVSPTFGQFLYVCARTTRSRLVIEYGTSFGVSTLYLAAALRDNGAGHLVTTELEPAKAARAQENLAEAGLADLVDVRVGDALDTLRAEPAEPVDLLLLDGAFSLYLPVLRLVEPYLRPGALVVAENAIEAVSDYRDHVRAPHNGYLTLTVPFDETRGNELSLRTG
>CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein
MDGTRSLSSSRRTFSFPCRQTCADGAVSTGELIFTEFDEKRPFRRAGHALVGRREHLRAVRTALAAVAAGDEAVILVEGGAGTGKSALLRAAGSSAHGLGLPVLPVSASSYEADEPLGLARRICEAAGTEPPALVDDIPEARRVVLERVTAWARGAPALLAIDDFQWCDAASLRCLSFLLRRGVRGLGVLASLTTGVSGADPVLVDEAQRSHPRPVRVRLGPLGRAEADRLVAGVLGPVPADLRAALFEWTGGNPFLLDEVLTELPGHPRGQVTDIVPRTVYPWLSGLLANGNPVCLPVVRALAALGDHASPTVLGEVAGLSALEVDYGIRALAELSLLRPGPRPAFAHPVVEAAVARQITPHELVRLRLVGARWLVTTGAPETSVISYLVDSGVADHPEGAELVVATARGMVDRSPPEEAVARLRDALSRRLPLPVRTELLQLCARAELDLDVGLAERRLGEAVVLLGCSRRPAVLVDHARALHALGRLDEAARLLCSVDAETPAGERDPALRDRVRLELATIVAGDPAVAMAPTSDPRDAVAAVVHLLVDGGVRGAPRHGLALGDLWDLLTPAAPDGLPLTWFTAVRALLSAGEGAGLLSYARLWVSAARQGTLRLALGHAQLAEALFRLDRIRCAGAAVNDVLRQWETLDHPGGCLPIIAAMPPVLDTLIERDELDSAVELLRQLPLNPDRRPHWHQLALLLRRGRLRRLLGDPAGGLSDLVRCGRVLRERGSRVPHPLRWRRHATVALLDLGRLDAARRLIDVELSDVRRRSPVGNELGVTLRLAGRVAGPSVGLGLLSQSVEVLEAGGSRVELARSLGELGTALSRMGRSRAARSRLRRACGLAEETGAVRLRACLEARLRDAGGRVRKQVTGVGALTAGERRVARLAATGHTNRQIAAELFITRRAVEMHLTQVYRKLGISGRGQLARALDDADDPVVRHGVVPAGR
>CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein
MHQTVIVGGNVRPSHAARRLQRQVQFAGQGRLHHLVPSGPGREGPAQCLLGGNRALVARLPLGSLDVQAHLHQTIFRLEPPQINAGINPELVVSVGVRRRPRDGSQGECVTVLERSQLSASGPGEQPNDPIASEDFSYLTGVSIPVDGGVAAGRPLRLPAL
>CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein
MTRRSRAGPLVLTRPLFLAAAAPQLSLAAYAHQDLPFERLVEVLNPTRSLSRHPLFQVMIAFQTTTGTVFDLPGLDARLEPDASRIAKFDLTCGLHERRGEDGGPAGISGALEYATDLFDEPTAASFADRLVRLLTDLVTGPDQALSSWDLLGSSERELVVRGWNDTELAVPPVSVAGFVHPGAPRWSYSSAGC
>CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein
MGGGAAGGGGGMAGGGARGRGGQGEDDGEHKRADYLLETDDVFGDGRLVAPSVLGDQPPTGR
>CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein
MTVSPRGRITLPAIAVDVIQTRLRATLPAALKTVGFGSTEDERRMLHQRAWQELEARGLVRTGDLDPFLEDAFQILARPPLAVWALLQTDRENGIDAVIAASGDFAVLAMQSGPENAPREEKELVLEAVRPTGLAHVAASLLPEHRPGKGQSVSCPSDLIEKATANASPGPGGLRASLTSHGMRPGEAEFIAEVLTSERLRYGEFSTRSFNRLAGKTTRSAYRVDVLDTSIGRYLLQHKPDGQGRPWFAMAPTDRTRMAGRIQELITSVTT
>CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein
MYFTDRGIEELEDRRGDEEVSFGYLADRLRAFVDENPRFEDAVERLATYLARDDGDEDAD
>CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein
MDRAVDRVRTWRRERDEATALLRSAGCRVNSFVPGTLVLLADGTHKPIEDNQLGDEVLASDPDTGEIGPQRVVATITNEGPKTLVDVSHTPSPDHLPDTVTDEHPFWVNNHGHWIHATDLTRGDTLLTPTGDHTTITHAHSYPHHHRVHNLTTNTIHTYYVLAGATPVLVHNATPEENCDLTLGAGPNAPEGVAFVDGNIDVSGGRELIEKSGQAHGCHTCSFRSPNTPNGRWIPDHQPPSSLVPPGSP
>CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein
MNLYPCPCCGYLVHNFPPGSHCICPICDWEDDLVQLRWPDISGANQVPLTESQLIYKDIGIADSNSTSKIRPLADFWSIDFGFRTIDEKIHNFEPNGAIEANWPEDRTRLYWWRPNFWRRLHKSP
>CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein
MSPRVVYQHVTHTIRHTPEGGITYEAFRVAANCGAESGPHAEQEAAQDWALRHTGRTGHDLFRRVFTGHAKVTRAE
>CP025990.1|AUS79460.1|3498163_3498349_+|excisionase
MRGDELLTVPEAMARLKIGRSALYDLLRTRRLASLTISRARRIPAHALDDYVQRHLEQASR
>CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein
MDIEQLMEKLGRSGVTVILKVDDERMAEGGEPWTLVMSGPGLGPEGFIRAESSSLSDCLEQGFNRLRSRPGDWEWLAEIS
>CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein
MAVAADGTVWPCVFSRWLPVGNVRVAPLAEILTGPTMLKTTTVLAAHFSARPSNPCVPNMCDPQCGPSCSPACVPANNCAPVGACVPSEY
>CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter
MLARRAYIPDELLSSEVADSWPLTVPCVAQLAEQGMVFDKPITFLVGENGSGKSTLVEAFAEAWGLDARGGRAGRKYVNDRPKTALGELIRWETTSAGARHKSGTRTKRRGYFLRAETAFGFMEAVSGMRGYWEEDTSEMSHGEGFLTVLANMFREPGFYLMDEPEAALSFKSCLRLVNLLYDLGQSGAQVICATHSPVLAATPGADIIEVGDDGFQRIEWEDLDLVDHWRRYMNNPTAYLRYITDE
>CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase
MVVDTSEADARFRQWMHGNLDRAAERFGVVVIGEPLLGWLDRSISAPVRKGGADYWLRVVSEDKQWIGGDFWTGNVDANVVTGLAKPRVLDVFEWEEWRQQRAEIMTRLPGSPCSPTDALRAEVDLADEWWTELRHTVDVIATTPTERVNSTQDKVADRIVHRFGDAVDPAVPAWETVHGDVHWANLFGPRFGLLDWELWGRGPVGTDAATLLCYSLLVPTIAQRVHKVFADVLDTEAGRFAQLYVIARLSRRTDSGEFPDLAGPLERRARALLNP
>CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein
MGALLLAAALVLASCSTEDASEPDTTDATTESTAAPSLTEEFPRETELLAPPVSTPLDATDIEPCALISDQEVSAMGYDAGSARTGFENSCTWDSTEHEGSRATLRANTEDGGLSWIYQIRDRYGVFDEMMVGEYPAVHAHTIEDESRCVLYTGIADDQYLNTNFVRNTLDDFDACQAAIEFTEAVIAELPAAS
>CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein
MSGSYEVDPEALPRAIAELKEAREVVAELEDRGIAISAKRSTRGDDGVSMNAGDQLARLGGDPGEGSLAATAAKLRAELDNTIFAFEEMLREYLELEQSATLPEYDGEVSQVSLPPDYWERQALNNGRRSGGDYVAI

Crispr_ID: CP025990_22

• CRISPR_ID: CP025990_22
• CRISPR_location: 3491989-3492486
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of CP025990_22

Consensus_repeat	Method
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder
GTTGGAACTCCTCGTAGGAGCGATGAGGACCCG	CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR

spacers of CP025990_22

>22.1|3492019|36|CP025990|CRISPRCasFinder
CCGACAGGCCACACCTCTGCCGGCGTGCACGGTGTG
>22.2|3492085|37|CP025990|CRISPRCasFinder,PILER-CR
GCGAGCCTGTATGACCTGCTCGCCGCCAAGAACGGAT
>22.3|3492152|35|CP025990|CRISPRCasFinder,PILER-CR
GCGGCACGCAGTCAGGCAGCGTGCAACCCACGTGG
>22.4|3492217|39|CP025990|CRISPRCasFinder,PILER-CR
CGGGCGGCACGTCATCCTGAACAACGTGTCCCGCCACCA
>22.5|3492286|38|CP025990|CRISPRCasFinder,PILER-CR
CCTATGCCCGGCCAACCTCGCTGACCGGCCCGTACACA
>22.6|3492354|36|CP025990|CRISPRCasFinder,PILER-CR
CCTTCCGATCGCCGGGGACATCGCCGCGACGTCCGC
>22.7|3492420|34|CP025990|CRISPRCasFinder
CCGAACCGGTCATCGTCGGGGCCTACGAGGACAC
>22.8|3492022|33|CP025990|CRT
ACAGGCCACACCTCTGCCGGCGTGCACGGTGTG
>22.9|3492088|34|CP025990|CRT
AGCCTGTATGACCTGCTCGCCGCCAAGAACGGAT
>22.10|3492155|32|CP025990|CRT
GCACGCAGTCAGGCAGCGTGCAACCCACGTGG
>22.11|3492220|36|CP025990|CRT
GCGGCACGTCATCCTGAACAACGTGTCCCGCCACCA
>22.12|3492289|35|CP025990|CRT
ATGCCCGGCCAACCTCGCTGACCGGCCCGTACACA
>22.13|3492357|33|CP025990|CRT
TCCGATCGCCGGGGACATCGCCGCGACGTCCGC
>22.14|3492423|31|CP025990|CRT
AACCGGTCATCGTCGGGGCCTACGAGGACAC

CRISPR arrays and Neighbor proteins around CP025990_22

CRISPR arrays

The CRISPR arrays of CP025990_22

>merge|CP025990|22|3491989-3492486|CRISPRCasFinder,CRT,PILER-CR
CAGCTGGAACCTCGTAGGAGCGATGAGGACCCGACAGGCCACACCTCTGCCGGCGTGCACGGTGTGGTTGGAACTCCTCGTAGGAGCGATGAGGACGCGAGCCTGTATGACCTGCTCGCCGCCAAGAACGGATGTCGGAACTCCTCGTAGGAGCGATGAGGACGCGGCACGCAGTCAGGCAGCGTGCAACCCACGTGGGTTGGAACTCCTCGTAGGAGCGATGAGGACCGGGCGGCACGTCATCCTGAACAACGTGTCCCGCCACCAGTTGGAACTCCTCGTAGGAGCGATGAGGACCCTATGCCCGGCCAACCTCGCTGACCGGCCCGTACACAGTTGGAACTCCTCGTAGGAGCGATGAGGACCCTTCCGATCGCCGGGGACATCGCCGCGACGTCCGCGTTGGAACTCCTCGTAGGAGCGATGAGGACCCGAACCGGTCATCGTCGGGGCCTACGAGGACACGTTGGAACTCCTCGTAGGAGCGATGAGGACCCG

>CP025990|22|21|3491989-3492484|CRISPRCasFinder
CAGCTGGAACCTCGTAGGAGCGATGAGGAC	CCGACAGGCCACACCTCTGCCGGCGTGCACGGTGTG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GCGAGCCTGTATGACCTGCTCGCCGCCAAGAACGGAT
GTCGGAACTCCTCGTAGGAGCGATGAGGAC	GCGGCACGCAGTCAGGCAGCGTGCAACCCACGTGG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CGGGCGGCACGTCATCCTGAACAACGTGTCCCGCCACCA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCTATGCCCGGCCAACCTCGCTGACCGGCCCGTACACA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCTTCCGATCGCCGGGGACATCGCCGCGACGTCCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCGAACCGGTCATCGTCGGGGCCTACGAGGACAC
GTTGGAACTCCTCGTAGGAGCGATGAGGACC

>CP025990|22|17|3491989-3492486|CRT
CAGCTGGAACCTCGTAGGAGCGATGAGGACCCG	ACAGGCCACACCTCTGCCGGCGTGCACGGTGTG
GTTGGAACTCCTCGTAGGAGCGATGAGGACGCG	AGCCTGTATGACCTGCTCGCCGCCAAGAACGGAT
GTCGGAACTCCTCGTAGGAGCGATGAGGACGCG	GCACGCAGTCAGGCAGCGTGCAACCCACGTGG
GTTGGAACTCCTCGTAGGAGCGATGAGGACCGG	GCGGCACGTCATCCTGAACAACGTGTCCCGCCACCA
GTTGGAACTCCTCGTAGGAGCGATGAGGACCCT	ATGCCCGGCCAACCTCGCTGACCGGCCCGTACACA
GTTGGAACTCCTCGTAGGAGCGATGAGGACCCT	TCCGATCGCCGGGGACATCGCCGCGACGTCCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGACCCG	AACCGGTCATCGTCGGGGCCTACGAGGACAC
GTTGGAACTCCTCGTAGGAGCGATGAGGACCCG

>CP025990|22|17|3492055-3492419|PILER-CR
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GCGAGCCTGTATGACCTGCTCGCCGCCAAGAACGGAT
GTCGGAACTCCTCGTAGGAGCGATGAGGAC	GCGGCACGCAGTCAGGCAGCGTGCAACCCACGTGG
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CGGGCGGCACGTCATCCTGAACAACGTGTCCCGCCACCA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCTATGCCCGGCCAACCTCGCTGACCGGCCCGTACACA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCTTCCGATCGCCGGGGACATCGCCGCGACGTCCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	unknown	unknown	gnl|CDD|226425
CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase	unknown	unknown	unknown
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	unknown	unknown	gnl|CDD|380463
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	unknown	unknown	gnl|CDD|226607
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	unknown	unknown	gnl|CDD|378935
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	unknown	unknown	gnl|CDD|377550
CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	unknown	unknown	gnl|CDD|379057
CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	unknown	unknown	gnl|CDD|223943
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	unknown	unknown	gnl|CDD|369438
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	unknown	unknown	gnl|CDD|379414
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	unknown	unknown	gnl|CDD|379504

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.08071e-14
CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein	gnl|CDD|380463	cd19540, LCL_NRPS-like, LCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs) and similar domains. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	9.56636e-56
CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.53334e-30
CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.34402e-14
CP025990.1|AUS79460.1|3498163_3498349_+|excisionase	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.27895e-07
CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase	gnl|CDD|377550	pfam05711, TylF, Macrocin-O-methyltransferase (TylF). This family consists of bacterial macrocin O-methyltransferase (TylF) proteins. TylF is responsible for the methylation of macrocin to produce tylosin. Tylosin is a macrolide antibiotic used in veterinary medicine to treat infections caused by Gram-positive bacteria and as an animal growth promoter in the swine industry. It is produced by several Streptomyces species. As with other macrolides, the antibiotic activity of tylosin is due to the inhibition of protein biosynthesis by a mechanism that involves the binding of tylosin to the ribosome, preventing the formation of the mRNA-aminoacyl-tRNA-ribosome complex. The structure of one representative sequence from this family, NovP, shows it to be an S-adenosyl-l-methionine-dependent O-methyltransferase that catalyzes the penultimate step in the biosynthesis of the aminocoumarin antibiotic novobiocin. Specifically, it methylates at 4-OH of the noviose moiety, and the resultant methoxy group is important for the potency of the mature antibiotic. It is likely that the key structural features of NovP are common to the rest of the family and include: a helical 'lid' region that gates access to the co-substrate binding pocket and an active centre that contains a 3-Asp putative metal binding site. A further conserved Asp probably acts as the general base that initiates the reaction by de-protonating the 4-OH group of the noviose unit.	1.14175e-129
CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein	gnl|CDD|379057	pfam13186, SPASM, Iron-sulfur cluster-binding domain. This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many radical SAM domain, pfam04055 proteins. The domain occurs in a number of proteins that modify a protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.	0.000130476
CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter	gnl|CDD|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	3.49919e-58
CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	2.24119e-17
CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	6.71984e-17
CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	4.31218e-17
CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein	gnl|CDD|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	4.53447e-45
CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein	gnl|CDD|379504	pfam14206, Cys_rich_CPCC, Cysteine-rich CPCC. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 68 and 104 amino acids in length. There are six conserved cysteines and a conserved CPCC sequence motif.	2.03318e-24

Protein sequences

>CP025990.1|AUS79456.1|3490086_3490542_-|DUF4440-domain-containing-protein
MVSTSRTSHDDHEQVHTVLLARERAIRDKDVLASSSVYVPDVTVFALAPPLSLRGQAAFDEAGTRAWYDSFTGPIGRQRRDLVVEVSGDVACAHCLVHLTGRRTDGVETDLWFRETLVLRRHDDTWLISHEHASVPLLMDGSGAAATQLHP
>CP025990.1|AUS79455.1|3489019_3489697_-|hypothetical-protein
MADLQAVVFDWRGTLVTTLNSEQWVREALRLLGRDQGAASVAAVHGAIERAAGNPNRLEAAGVDSDKGLHHDTYYSVFSEAGLDAELADALYTVESDPAYNHFADDVAETLHAVSARGCGVAILSDIHFDLRPVFAEAGLDRFVNAFVLSFERGMQKPQLAMFRSALDELGTEPRRTLMVGDRASYDGVAVELGMPTMLVPPLTDARQRRLHHVRNLVGSVPTSS
>CP025990.1|AUS81775.1|3487068_3487974_-|macrocin-O-methyltransferase
MTLPCRRTRRGTGPDPRCLGGAPGAGTRTNHEGRVAVIARQNTSHSSAPDTSETGAALYLDLLERVVTNLIYEDDGIPNRYLPDGRFDLDRRQNGIDWPSVAHTMVGLKRVRNVRYCLERVLAEGVPGDFIETGVWRGGVCVFARGVLKAYGCTDRAVWVADSFQGIPDTGPDGHHLDRALALHEANHVLGVPLDVVRRNFQQYGLLDDQVRFLPGWFRDTLPTAPMERLAVLRLDGDLYESTTDALTNLYPKLSPGGFVIIDDFVIEACAQAVHDFRQRAGVEEPLVAIDDGGVYWRREN
>CP025990.1|AUS79454.1|3484951_3485644_+|methyltransferase
MNSLTDPRVADVIARLHQEAEAADQPVLEDRPGGAMADEDLIRRTLEEEARDYRSLYHRYADNYFSVSPTFGQFLYVCARTTRSRLVIEYGTSFGVSTLYLAAALRDNGAGHLVTTELEPAKAARAQENLAEAGLADLVDVRVGDALDTLRAEPAEPVDLLLLDGAFSLYLPVLRLVEPYLRPGALVVAENAIEAVSDYRDHVRAPHNGYLTLTVPFDETRGNELSLRTG
>CP025990.1|AUS79453.1|3480091_3482953_-|hypothetical-protein
MDGTRSLSSSRRTFSFPCRQTCADGAVSTGELIFTEFDEKRPFRRAGHALVGRREHLRAVRTALAAVAAGDEAVILVEGGAGTGKSALLRAAGSSAHGLGLPVLPVSASSYEADEPLGLARRICEAAGTEPPALVDDIPEARRVVLERVTAWARGAPALLAIDDFQWCDAASLRCLSFLLRRGVRGLGVLASLTTGVSGADPVLVDEAQRSHPRPVRVRLGPLGRAEADRLVAGVLGPVPADLRAALFEWTGGNPFLLDEVLTELPGHPRGQVTDIVPRTVYPWLSGLLANGNPVCLPVVRALAALGDHASPTVLGEVAGLSALEVDYGIRALAELSLLRPGPRPAFAHPVVEAAVARQITPHELVRLRLVGARWLVTTGAPETSVISYLVDSGVADHPEGAELVVATARGMVDRSPPEEAVARLRDALSRRLPLPVRTELLQLCARAELDLDVGLAERRLGEAVVLLGCSRRPAVLVDHARALHALGRLDEAARLLCSVDAETPAGERDPALRDRVRLELATIVAGDPAVAMAPTSDPRDAVAAVVHLLVDGGVRGAPRHGLALGDLWDLLTPAAPDGLPLTWFTAVRALLSAGEGAGLLSYARLWVSAARQGTLRLALGHAQLAEALFRLDRIRCAGAAVNDVLRQWETLDHPGGCLPIIAAMPPVLDTLIERDELDSAVELLRQLPLNPDRRPHWHQLALLLRRGRLRRLLGDPAGGLSDLVRCGRVLRERGSRVPHPLRWRRHATVALLDLGRLDAARRLIDVELSDVRRRSPVGNELGVTLRLAGRVAGPSVGLGLLSQSVEVLEAGGSRVELARSLGELGTALSRMGRSRAARSRLRRACGLAEETGAVRLRACLEARLRDAGGRVRKQVTGVGALTAGERRVARLAATGHTNRQIAAELFITRRAVEMHLTQVYRKLGISGRGQLARALDDADDPVVRHGVVPAGR
>CP025990.1|AUS79452.1|3479479_3479965_+|hypothetical-protein
MHQTVIVGGNVRPSHAARRLQRQVQFAGQGRLHHLVPSGPGREGPAQCLLGGNRALVARLPLGSLDVQAHLHQTIFRLEPPQINAGINPELVVSVGVRRRPRDGSQGECVTVLERSQLSASGPGEQPNDPIASEDFSYLTGVSIPVDGGVAAGRPLRLPAL
>CP025990.1|AUS79451.1|3477803_3478388_-|hypothetical-protein
MTRRSRAGPLVLTRPLFLAAAAPQLSLAAYAHQDLPFERLVEVLNPTRSLSRHPLFQVMIAFQTTTGTVFDLPGLDARLEPDASRIAKFDLTCGLHERRGEDGGPAGISGALEYATDLFDEPTAASFADRLVRLLTDLVTGPDQALSSWDLLGSSERELVVRGWNDTELAVPPVSVAGFVHPGAPRWSYSSAGC
>CP025990.1|AUS81774.1|3477170_3477359_-|hypothetical-protein
MGGGAAGGGGGMAGGGARGRGGQGEDDGEHKRADYLLETDDVFGDGRLVAPSVLGDQPPTGR
>CP025990.1|AUS79450.1|3476358_3477174_-|hypothetical-protein
MTVSPRGRITLPAIAVDVIQTRLRATLPAALKTVGFGSTEDERRMLHQRAWQELEARGLVRTGDLDPFLEDAFQILARPPLAVWALLQTDRENGIDAVIAASGDFAVLAMQSGPENAPREEKELVLEAVRPTGLAHVAASLLPEHRPGKGQSVSCPSDLIEKATANASPGPGGLRASLTSHGMRPGEAEFIAEVLTSERLRYGEFSTRSFNRLAGKTTRSAYRVDVLDTSIGRYLLQHKPDGQGRPWFAMAPTDRTRMAGRIQELITSVTT
>CP025990.1|AUS79449.1|3475877_3476060_-|hypothetical-protein
MYFTDRGIEELEDRRGDEEVSFGYLADRLRAFVDENPRFEDAVERLATYLARDDGDEDAD
>CP025990.1|AUS79457.1|3494007_3494757_-|hypothetical-protein
MDRAVDRVRTWRRERDEATALLRSAGCRVNSFVPGTLVLLADGTHKPIEDNQLGDEVLASDPDTGEIGPQRVVATITNEGPKTLVDVSHTPSPDHLPDTVTDEHPFWVNNHGHWIHATDLTRGDTLLTPTGDHTTITHAHSYPHHHRVHNLTTNTIHTYYVLAGATPVLVHNATPEENCDLTLGAGPNAPEGVAFVDGNIDVSGGRELIEKSGQAHGCHTCSFRSPNTPNGRWIPDHQPPSSLVPPGSP
>CP025990.1|AUS79458.1|3495427_3495805_-|hypothetical-protein
MNLYPCPCCGYLVHNFPPGSHCICPICDWEDDLVQLRWPDISGANQVPLTESQLIYKDIGIADSNSTSKIRPLADFWSIDFGFRTIDEKIHNFEPNGAIEANWPEDRTRLYWWRPNFWRRLHKSP
>CP025990.1|AUS79459.1|3496717_3496948_-|hypothetical-protein
MSPRVVYQHVTHTIRHTPEGGITYEAFRVAANCGAESGPHAEQEAAQDWALRHTGRTGHDLFRRVFTGHAKVTRAE
>CP025990.1|AUS79460.1|3498163_3498349_+|excisionase
MRGDELLTVPEAMARLKIGRSALYDLLRTRRLASLTISRARRIPAHALDDYVQRHLEQASR
>CP025990.1|AUS81776.1|3499649_3499892_-|hypothetical-protein
MDIEQLMEKLGRSGVTVILKVDDERMAEGGEPWTLVMSGPGLGPEGFIRAESSSLSDCLEQGFNRLRSRPGDWEWLAEIS
>CP025990.1|AUS79461.1|3502078_3502351_+|hypothetical-protein
MAVAADGTVWPCVFSRWLPVGNVRVAPLAEILTGPTMLKTTTVLAAHFSARPSNPCVPNMCDPQCGPSCSPACVPANNCAPVGACVPSEY
>CP025990.1|AUS79462.1|3502365_3503109_+|ABC-transporter
MLARRAYIPDELLSSEVADSWPLTVPCVAQLAEQGMVFDKPITFLVGENGSGKSTLVEAFAEAWGLDARGGRAGRKYVNDRPKTALGELIRWETTSAGARHKSGTRTKRRGYFLRAETAFGFMEAVSGMRGYWEEDTSEMSHGEGFLTVLANMFREPGFYLMDEPEAALSFKSCLRLVNLLYDLGQSGAQVICATHSPVLAATPGADIIEVGDDGFQRIEWEDLDLVDHWRRYMNNPTAYLRYITDE
>CP025990.1|AUS79463.1|3503119_3503950_+|aminoglycoside-phosphotransferase
MVVDTSEADARFRQWMHGNLDRAAERFGVVVIGEPLLGWLDRSISAPVRKGGADYWLRVVSEDKQWIGGDFWTGNVDANVVTGLAKPRVLDVFEWEEWRQQRAEIMTRLPGSPCSPTDALRAEVDLADEWWTELRHTVDVIATTPTERVNSTQDKVADRIVHRFGDAVDPAVPAWETVHGDVHWANLFGPRFGLLDWELWGRGPVGTDAATLLCYSLLVPTIAQRVHKVFADVLDTEAGRFAQLYVIARLSRRTDSGEFPDLAGPLERRARALLNP
>CP025990.1|AUS79464.1|3505886_3506471_-|DUF3558-domain-containing-protein
MGALLLAAALVLASCSTEDASEPDTTDATTESTAAPSLTEEFPRETELLAPPVSTPLDATDIEPCALISDQEVSAMGYDAGSARTGFENSCTWDSTEHEGSRATLRANTEDGGLSWIYQIRDRYGVFDEMMVGEYPAVHAHTIEDESRCVLYTGIADDQYLNTNFVRNTLDDFDACQAAIEFTEAVIAELPAAS
>CP025990.1|AUS79465.1|3506511_3506925_-|hypothetical-protein
MSGSYEVDPEALPRAIAELKEAREVVAELEDRGIAISAKRSTRGDDGVSMNAGDQLARLGGDPGEGSLAATAAKLRAELDNTIFAFEEMLREYLELEQSATLPEYDGEVSQVSLPPDYWERQALNNGRRSGGDYVAI

Crispr_ID: CP025990_24

• CRISPR_ID: CP025990_24
• CRISPR_location: 3572166-3572439
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP025990_24

Consensus_repeat	Method
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGG	CRISPRCasFinder
GAAAGCCCCGCGCAAGCGGGGGTGA	CRT

spacers of CP025990_24

>24.1|3572195|32|CP025990|PILER-CR
GGGTGCGGCCGGTCGGACCTGACGGCGCTCCG
>24.2|3572256|32|CP025990|PILER-CR
TAGCCGGGTGAATCCCGCTCGGCGGGCGGCGC
>24.3|3572317|32|CP025990|PILER-CR
CCCGACCACCGCAGCGTGTTCGTCGTGAGCTC
>24.4|3572378|32|CP025990|PILER-CR
GAGGAACTTGTCGCGCGCAACCGACCCGGTGG
>24.5|3572196|31|CP025990|CRISPRCasFinder
GGTGCGGCCGGTCGGACCTGACGGCGCTCCG
>24.6|3572257|31|CP025990|CRISPRCasFinder
AGCCGGGTGAATCCCGCTCGGCGGGCGGCGC
>24.7|3572318|31|CP025990|CRISPRCasFinder
CCGACCACCGCAGCGTGTTCGTCGTGAGCTC
>24.8|3572379|31|CP025990|CRISPRCasFinder
AGGAACTTGTCGCGCGCAACCGACCCGGTGG
>24.9|3572191|36|CP025990|CRT
TCCGGGGTGCGGCCGGTCGGACCTGACGGCGCTCCG
>24.10|3572252|36|CP025990|CRT
TCCGTAGCCGGGTGAATCCCGCTCGGCGGGCGGCGC
>24.11|3572313|36|CP025990|CRT
GCCGCCCGACCACCGCAGCGTGTTCGTCGTGAGCTC
>24.12|3572374|36|CP025990|CRT
GCCGGAGGAACTTGTCGCGCGCAACCGACCCGGTGG

CRISPR arrays and Neighbor proteins around CP025990_24

CRISPR arrays

The CRISPR arrays of CP025990_24

>merge|CP025990|24|3572166-3572439|PILER-CR,CRISPRCasFinder,CRT
GAAAGCCCCGCGCAAGCGGGGGTGATCCGGGGTGCGGCCGGTCGGACCTGACGGCGCTCCGGAAAGCCCCGCGCAAGCGGGGGTGATCCGTAGCCGGGTGAATCCCGCTCGGCGGGCGGCGCGAAAGCCCCGCGCAAGCGGGGGTGAGCCGCCCGACCACCGCAGCGTGTTCGTCGTGAGCTCGAAAGCCCCGCGCAAGCGGGGGTGAGCCGGAGGAACTTGTCGCGCGCAACCGACCCGGTGGGAAAGCCCCGCGCAAGCGGGGGTGAGCCGG

>CP025990|24|18|3572166-3572438|PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGATCCG	GGGTGCGGCCGGTCGGACCTGACGGCGCTCCG
GAAAGCCCCGCGCAAGCGGGGGTGATCCG	TAGCCGGGTGAATCCCGCTCGGCGGGCGGCGC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CCCGACCACCGCAGCGTGTTCGTCGTGAGCTC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GAGGAACTTGTCGCGCGCAACCGACCCGGTGG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG

>CP025990|24|23|3572166-3572439|CRISPRCasFinder
GAAAGCCCCGCGCAAGCGGGGGTGATCCGG	GGTGCGGCCGGTCGGACCTGACGGCGCTCCG
GAAAGCCCCGCGCAAGCGGGGGTGATCCGT	AGCCGGGTGAATCCCGCTCGGCGGGCGGCGC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGC	CCGACCACCGCAGCGTGTTCGTCGTGAGCTC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGG	AGGAACTTGTCGCGCGCAACCGACCCGGTGG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGG

>CP025990|24|18|3572166-3572434|CRT
GAAAGCCCCGCGCAAGCGGGGGTGA	TCCGGGGTGCGGCCGGTCGGACCTGACGGCGCTCCG
GAAAGCCCCGCGCAAGCGGGGGTGA	TCCGTAGCCGGGTGAATCCCGCTCGGCGGGCGGCGC
GAAAGCCCCGCGCAAGCGGGGGTGA	GCCGCCCGACCACCGCAGCGTGTTCGTCGTGAGCTC
GAAAGCCCCGCGCAAGCGGGGGTGA	GCCGGAGGAACTTGTCGCGCGCAACCGACCCGGTGG
GAAAGCCCCGCGCAAGCGGGGGTGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81785.1|3565365_3567954_-|peptidase-M28	unknown	unknown	gnl|CDD|349463
CP025990.1|AUS79513.1|3575957_3576785_+|hypothetical-protein	unknown	unknown	gnl|CDD|379312
CP025990.1|AUS79506.1|3564161_3565190_-|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
CP025990.1|AUS79511.1|3574019_3574658_-|transcriptional-regulator	unknown	unknown	unknown
CP025990.1|AUS79505.1|3563191_3563956_-|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|213873
CP025990.1|AUS79517.1|3581656_3581971_+|hypothetical-protein	unknown	unknown	gnl|CDD|365941
CP025990.1|AUS79516.1|3578635_3579013_+|adenosylmethionine-decarboxylase	unknown	unknown	gnl|CDD|376892
CP025990.1|AUS79512.1|3574845_3575301_-|hypothetical-protein	unknown	unknown	gnl|CDD|227269
CP025990.1|AUS81784.1|3562307_3563162_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|131480
CP025990.1|AUS79509.1|3570970_3571198_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79519.1|3582686_3583001_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79503.1|3560293_3560917_+|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
CP025990.1|AUS79518.1|3582054_3582369_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79502.1|3558496_3559669_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|185755
CP025990.1|AUS79504.1|3561128_3562208_+|aldose-epimerase	unknown	unknown	gnl|CDD|185699
CP025990.1|AUS79510.1|3572758_3573979_-|peptidase-dimerization-protein	unknown	unknown	gnl|CDD|349944
CP025990.1|AUS79507.1|3568209_3569466_-|peptidase-S8	unknown	unknown	gnl|CDD|173790
CP025990.1|AUS79515.1|3577461_3578616_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79508.1|3569776_3570757_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79514.1|3576781_3577537_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81785.1|3565365_3567954_-|peptidase-M28	gnl|CDD|349463	cd06244, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	7.53938e-57
CP025990.1|AUS79513.1|3575957_3576785_+|hypothetical-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.08398e-08
CP025990.1|AUS79506.1|3564161_3565190_-|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	8.02984e-46
CP025990.1|AUS79505.1|3563191_3563956_-|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|213873	TIGR03856, F420_MSMEG_2906, probable F420-dependent oxidoreductase, MSMEG_2906 family. This model describes a small family of enzymes in the bacterial luciferase-like monooxygenase family, which includes F420-dependent enzymes such as N5,N10-methylenetetrahydromethanopterin reductase as well as FMN-dependent enzymes. All members of this family are from species that produce coenzyme F420; SIMBAL analysis suggests that members of this family bind F420 rather than FMN. [Unknown function, Enzymes of unknown specificity].	1.24903e-106
CP025990.1|AUS79517.1|3581656_3581971_+|hypothetical-protein	gnl|CDD|365941	pfam00198, 2-oxoacid_dh, 2-oxoacid dehydrogenases acyltransferase (catalytic domain). These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain.	0.0067939
CP025990.1|AUS79516.1|3578635_3579013_+|adenosylmethionine-decarboxylase	gnl|CDD|376892	pfam02675, AdoMet_dc, S-adenosylmethionine decarboxylase. This family contains several S-adenosylmethionine decarboxylase proteins from bacterial and archaebacterial species. S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the biosynthesis of spermidine and spermine, is first synthesized as a proenzyme, which is cleaved post translationally to form alpha and beta subunits. The alpha subunit contains a covalently bound pyruvoyl group derived from serine that is essential for activity.	3.55485e-26
CP025990.1|AUS79512.1|3574845_3575301_-|hypothetical-protein	gnl|CDD|227269	COG4933, COG4933, Uncharacterized conserved protein [Function unknown].	2.43431e-11
CP025990.1|AUS79503.1|3560293_3560917_+|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	8.78693e-82
CP025990.1|AUS79502.1|3558496_3559669_-|glycosyl-hydrolase	gnl|CDD|185755	cd09216, GH64-LPHase-like, glycoside hydrolase family 64: laminaripentaose-producing, beta-1,3-glucanase (LPHase)-like. This subfamily is represented by the laminaripentaose-producing, beta-1,3-glucanase (LPHase) of Streptomyces matensis and related bacterial and ascomycete proteins. LPHase is a member of glycoside hydrolase family 64 (GH64), it is an inverting enzyme involved in the cleavage of long-chain polysaccharide beta-1,3-glucans, into specific pentasaccharide oligomers. LPHase is a two-domain crescent fold structure: one domain is composed of 10 beta-strands, eight coming from the N-terminus of the protein and two from the C-terminal region, and the protein has a second inserted domain; this cd includes both domains. This protein has an electronegative, substrate-binding cleft, and conserved Glu and Asp residues involved in the cleavage of the beta-1,3-glucan, laminarin, a plant and fungal cell wall component. Among bacteria, many beta-1,3-glucanases are implicated in fungal cell wall degradation. Also included in this family is GluB , the beta-1,3-glucanase B from Lysobacter enzymogenes Strain N4-7. Recombinant GluB demonstrated higher relative activity toward the branched-chain beta-1,3 glucan substrate zymosan A than toward linear beta-1,3 glucan substrates. Sometimes these two domains are found associated with other domains such as in the Catenulispora acidiphila DSM 44928 carbohydrate binding family 6 protein in which they are positioned N-terminal of a carbohydrate binding module, family 6 (CBM_6) domain. In the Cellulosimicrobium cellulans, glucan endo-1,3-beta-glucosidase, they are positioned N-terminal of a RICIN, carbohydrate-binding domain.	1.96542e-147
CP025990.1|AUS79504.1|3561128_3562208_+|aldose-epimerase	gnl|CDD|185699	cd09022, Aldose_epim_Ec_YihR, Aldose 1-epimerase, similar to Escherichia coli YihR. Proteins similar to Escherichia coli YihR are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	3.61055e-118
CP025990.1|AUS79510.1|3572758_3573979_-|peptidase-dimerization-protein	gnl|CDD|349944	cd08659, M20_ArgE_DapE-like, Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like. Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE) like family of enzymes catalyze analogous reactions and share a common activator, the metal ion (usually Co2+ or Zn2+). ArgE catalyzes a broad range of substrates, including N-acetylornithine, alpha-N-acetylmethionine and alpha-N-formylmethionine, while DapE catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelate (L,L-SDAP) to L,L-diaminopimelate and succinate. Proteins in this family are mostly bacterial and have been inferred by homology as being related to both ArgE and DapE. This family also includes N-acetyl-L-citrulline deacetylase (ACDase; acetylcitrulline deacetylase), a unique, novel enzyme found in Xanthomonas campestris, a plant pathogen, in which N-acetyl-L-ornithine is the substrate for transcarbamoylation reaction, and the product is N-acetyl-L-citrulline. Thus, in the arginine biosynthesis pathway, ACDase subsequently catalyzes the hydrolysis of N-acetyl-L-citrulline to acetate and L-citrulline.	9.29131e-53
CP025990.1|AUS79507.1|3568209_3569466_-|peptidase-S8	gnl|CDD|173790	cd04077, Peptidases_S8_PCSK9_ProteinaseK_like, Peptidase S8 family domain in ProteinaseK-like proteins. The peptidase S8 or Subtilase clan of proteases have a Asp/His/Ser catalytic triad that is not homologous to trypsin. This CD contains several members of this clan including: PCSK9 (Proprotein convertase subtilisin/kexin type 9), Proteinase_K, Proteinase_T, and other subtilisin-like serine proteases. PCSK9 posttranslationally regulates hepatic low-density lipoprotein receptors (LDLRs) by binding to LDLRs on the cell surface, leading to their degradation. The binding site of PCSK9 has been localized to the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR. Characterized Proteinases K are secreted endopeptidases with a high degree of sequence conservation. Proteinases K are not substrate-specific and function in a wide variety of species in different pathways. It can hydrolyze keratin and other proteins with subtilisin-like specificity. The number of calcium-binding motifs found in these differ. Proteinase T is a novel proteinase from the fungus Tritirachium album Limber. The amino acid sequence of proteinase T as deduced from the nucleotide sequence is about 56% identical to that of proteinase K.	9.19689e-115
CP025990.1|AUS81784.1|3562307_3563162_-|alpha/beta-hydrolase	gnl|CDD|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	4.8259e-21
CP025990.1|AUS79514.1|3576781_3577537_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	9.10574e-06

Protein sequences

>CP025990.1|AUS79509.1|3570970_3571198_-|hypothetical-protein
MTVTADDPVPGRRWRAHLLHGRAGSEATSNEGHGQSLEPSRASSNGTSSWAWAWRRRSTSRERWVTEGVTHPLPV
>CP025990.1|AUS79508.1|3569776_3570757_+|hypothetical-protein
MIGATWSTSDQVDGDGTRQTTDRTSPADEPFPSTLRAAIAASGLSLDRIRYRLEQHGHHISVATLSYWQSGRSRPERRESLNALRQLESLLTLPPTALRSLLGPPRPRGRNRRLTIPSIASLWPEVPAVPELLSSFDIRSDTMLERISHHDHYSIGGSGDVRRIRTRQVLRARGEGPDRCLVVFDPERPGLPSLTPHAIRNCRVGRVARSGGTGLVVAELVLPGPLARGATTILEFELRAQPGRPAATRTTECSRRFVAPVREYLLEVSFSPEALPVAPHRFVRPADRRKAPSRSPLTLGPEQCAHVVELDVPPGTVGISWGWPAP
>CP025990.1|AUS79507.1|3568209_3569466_-|peptidase-S8
MTNNWRNYLRTFGGVGAAVALSLTALTGAAGANPTADQVGKVLHADSARAIKGSYLVVLDETSPRLASGVTATADGLVTQYGGSVERTYSTAIQGFEAALTEGQARRLAADPSVAYVEQNQRVSIDLTAAPATTRDVGVQAVQTNPPSWGLDRVDQRNLPLDNRYEYTTTGSGVTVYVLDTGVNISHPTFGGRASYGYNFVNNTPNAEDGNGHGTHVAGTVAGSQFGVAKNARIVAVQVLGATGGGTTAGVVAGVNWVAANASGPSVANLSLGGGVSTALDQAVVNAINSGVTHVVAAGNNNGNANNYSPARVGPAITVGATTSTDARASYSNFGKVDIFAPGSNITSAWRAGGTYTGNGTSFASPHVAGAAARYLQSNPGATPAQVKSALQSWGTSGIVTNPGTGSTNRLLYVPPAS
>CP025990.1|AUS81785.1|3565365_3567954_-|peptidase-M28
MRISRPTAGLLVAALVAATAAAAPPATAAEPPPPDAPPGVDVSDRDAVLAADLADPARVRPRGENRPGTPGERVEAGTPSSFSESDERGYPRRTQLRIYPDDPADRSVKLGLVPYHELAPRLNDLQAESDRVSVEVLGESVLGRDIYLVTLTAPETPEDSAQQRRWRDAIRTDPRAAAADEELRAGYKAPMWFNANIHGDEWEGTDGSLRVIEQLATSEDPEDLRLLETSRLYFTVSHNPDGRVAGTRQNAAGFDLNRDFVTVANPETEAVRKVAINGQSLVMLDLHGYVNPTLLSPNTAPHVQNAEYDLYLKHAWPNALGMERAIAGLGHPETQRADIPIRDRAPGDWDDWLPMYTPMYAMLQGTHGHTVEVPLRVNRQDYENQPVAELRRRAAVNTDVAEATILSTIDYVDANRDELVADQIEFFRRAGAGEQQRRIPDDYIPGFGEADRYTTEFPRGYVIPAAGEGTSEPAAARLVNLLLDNGVEVRRTEAGFRVGREEYPPGSYLVDLRQPRRAIANSLLEDGADLTERVPRTYANSALSHGLLWGAEVAPVRGGLTVRSRPVEEPVASGGVDVAPGRDLAVALTDGSDVRVVNDLLGRGHQVHRSSEGVIVVPASARADALAASREHGVRFTEAPSGDERTPVGQRPVVAAAVSPDELVALRGMGFEVRPVSTAVLNEGFDWRRVDVLYVSAGLELSGLREEARADLTEFLGRGGVVTRGAVGARFNTEAGLLPVDVVRGRSDANGIVEVGAGDGWVGSGAAPHSFVYSPLWFEGLGDGVTVEQRYGPDAPLVAGHWRPEQDGTGGQVEAAGRPAVVSGVGGAGTPTVLFGTEPLFRDHPKGLYSQVARALYWTASS
>CP025990.1|AUS79506.1|3564161_3565190_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MNRFPSVRTRGLTRRHFLIGGAGATVALLAGCADGSGGDTGAGASGAPAAEGFPTSVDHQFGTTELDRAPERVVALGWGDGDTLLALGVVPVASVDWFRAYDDGFGPWARERRGDGEVEVLTGPEFSPEGILAQRPDLVTMTKSDNDRSVYEMFAELVPTLSGPATDISYGTHWRDQTRLIAEVLGRPEEGQALIGEVEDAFADARARYPQFEGRTCSVVWWDEASYAAYVEGDTRVDTLRDLGFVNSPAIEELRGGDGFTVDVSREEAGLLEADVCVVVSMQPAERIEQDTLLQGTAMAREGRMIVLSDADAQNAFSMGTVLSLPYALDLLLPQLAEALAD
>CP025990.1|AUS79505.1|3563191_3563956_-|LLM-class-F420-dependent-oxidoreductase
MQQVKIGVQLEPQATTTEALRRAWTGADELGLDTAYVWDHFYPLHGDPDAAHFEAYALLAAMAVETSRIRFGALVTCNSYRNPNLLADMSRTIDQLGGGRFILGIGSGWFERDYTEYGYTFGTAIGRLRKLETDLPVIKQRLSVLNPGPAGPMPILIGGSGEKVTLRLVAEHADAWNAFGPPDNFAHKNRVLDEWCERVGRDPREVHRTVLIRPHELETWRDYVEAGAQELIVSLEDPFPLDGVAELLREVRAA
>CP025990.1|AUS81784.1|3562307_3563162_-|alpha/beta-hydrolase
MELWTESIGDPANPPVLLVAGANSSALGWPDEFVARLVDGGRRVLRYDHRDTGRSTTRPFSDAPYPVARLAEDALGVLDGWGLRSAHVVGLSLGSTLGQLLALDHPERLRGLTLMLGAALDVDFVGNLRRAHTGEPDPGGLPLPRRDVLDVLARRAEPPSDRAAALDRRVEEWRALAGPSVFDAAEFRRWEERAIEHAGTLEQPSAHGAAEPVPTERGRELRGVRVPTLVVQGELDPLNPPPHGRHLADLIPGAVLWEVAGLGHALPGALHGVLADRILAHTAE
>CP025990.1|AUS79504.1|3561128_3562208_+|aldose-epimerase
MSRSTERSAGSALSRRAALGAAGGLGLLGVTGIAGTSQASTADGPGTHPATGPRPPVGEATGRLYEIRAGRHAVVVAGVAATLLSWKVDGEERLLTHEPHSVGDSYQGKTIVPWPNRIDRGHYTFDDAEYQVPVNEPERNTALHGLVNWVEWEPVEHSRDRVVLDYQLHPQYGYPFRLGLRMEYAVSARGIRARLTATNLGRARAPFGAAFHPYFQLGSETIDDMRVRLPADAYYTVDDRLLPTGIAEVDGTGMDFRVPRELGTTELDTAYTRLLREADGTAVTRLSRRGGPTIELWVDENYRYLQVYTDDGPPPGRAGRAGITVEPMTCAPDAFNSGDGLVLLDPGAEFHGSWGLRSA
>CP025990.1|AUS79503.1|3560293_3560917_+|superoxide-dismutase
MAPYTLPDLDYDYSALAPAITGEINELHHSKHHAAYVKGANDTLEKLAAAREADDFGSIVGLQTTLAFNLAGHAHHVIWWKVLSPNGGDKPVGELAAAIDEEFGSFDRFRAQFNAVATTIQGNGWAVLAWDPIGQRLITQQIRDHHANSVLPSVPILLFDVWEHAFYLQYRNVKPDYVNALWNVVDWAEVGRRFEDARAGRNGLLLP
>CP025990.1|AUS79502.1|3558496_3559669_-|glycosyl-hydrolase
MVTRRMFLGGLAATATSGALIGSGTVSAASGPVAPAAARVPNSLPFTVVNDSGRYPNSALWMHLVGRELPSDRPVRMTPDGTLAYVSASDNDADGFADYAIPLNGAGDTRFDLPINFSGRAYFSVTEKIRFRVNPDDTLAYPAGWVESDPNYRILHDCMEFTYDATGMYCNTTKVDMFSMPLGIELTGSETQRTGFLVDGGREAVLAAMRGNPDFANLVVDDLRVIAPSHGIDSGLFSPTFYDSYVDAVWNRYQSDTLTVTANHTDFTGQVQGGLFTFTGGVSPFEKPTTRDVLFCDGALHAPNDGISGPVAAVLGASLNRSTLLDSARAPILDPDAFYLDQTSNHYSRVLHENMVDGKVYGFAFDDVGDFASYVQDHAPAGITVSINPF
>CP025990.1|AUS79510.1|3572758_3573979_-|peptidase-dimerization-protein
MPVVNMINHGGERDVLAAATEDHESVIALTRELVAIPSRGGVDPYEPVLNRLSGWLEQRNLVVTVLRDKAGATVGLTCEIRGAHPGPRWVLDACLDTAPFGDEAAWTHPPTSATIVDGWLYGRGSADSKTGAAIFCHVATRLATMTDQLRGSLVLLFDVDEHTGAFGGAKRYFEGPDAPDDVAGVMIGYPGMDKLVVGGRGVHRATLHVHGVASHSGGSKTTPSAIEKAANLVRVLSAAELAASASSEFPMAGKLTVTAIEGGQGYSVTPDLCTLHVDIRTTRDFDDEDAARLLKHLVAQVDDAWPGTHPTLIQVDTRWPAFALAEDSRLRAAILDAATAVGVEVEPKIAGPSNIGNYLAGLNIPATAGFGVDYVGLHGTDERIRLDTIPTIQAIYHAAVLALLRP
>CP025990.1|AUS79511.1|3574019_3574658_-|transcriptional-regulator
MLSGWELGKHITSIRYRKVLAGYYAQPPEVLFAHQDQRLTAGSETPLLLVGHHDLRAAMTEVVHGAGQYLAVVGSRSRDAAYLDAIEAVLVQRPELVHYRVLFGPPRHQVLKDHLLRLVKIRDPHDRSLGVKTLHIGVVEDAPRAPERFFCASESTAVVPIPSLTSSEAFDSGVLFEAAVAERLIDHARQVYAGARRIESDQALRDLPAVPS
>CP025990.1|AUS79512.1|3574845_3575301_-|hypothetical-protein
MSLDPEYYELIWQRLKRHEFRRRYLADRPTTWFVYLTAPVSKLAAVIDLDEAVVASPTRIAEIAEQARVGNGESVFEYLKDLENGFALPIRKVREFSGFTAEELTGMLGKFHPPQGYTRVDKNLTLAGVCDKLMAAEPVRELVVEHPASVI
>CP025990.1|AUS79513.1|3575957_3576785_+|hypothetical-protein
MPSARRVLRSPGVTATSNAVAVVESYARRARFARAEATAVRRPRLLHGLLRTGPHVVEIPCGAGHFLTEYARAGATVTLVDACPEMLAAAVEHAANAGVPAEHTVPAVAYLHELEFLSEVELVVAPNAALNQLARQSSLTDMLTALRQALRPGVEVLAQVACTHPGGGVDSATFYDVARQHRVWFPDRWFDPAHAGGAVLRRRRQQRDDDRLRIEFDYVDPAGHSLYTTTVELALFSAQQLRDTFTAAGFVHVRLLAGQHGLSEVLATTDPGVQR
>CP025990.1|AUS79514.1|3576781_3577537_+|class-I-SAM-dependent-methyltransferase
MSGNETVADADEYWRRYYAEQFRFGLGTEDILAALMTIPPVQTWVDLGCGSESMLWAIALRAQQLVAVDVDRTRLEILGQFAELAQPRGVHTTALALCGRAEPDDFLARCRSLVVRVRADCLDRSLPADLTATTFDLVTQFGLLGLCRNDEHFTTRFAEIHRLLAPGGWTAGANWVARDPRGRVELTHQLYQNAATQAGAHLLLLKRITIADPEFPAVWTYVGRTQPCPQAEPLSHQNQASCSSPRSGSRI
>CP025990.1|AUS79515.1|3577461_3578616_+|hypothetical-protein
MPTSRTAQSPEPGELFFAPVGIAHLTSDNTDLLRAAARGKQRLRVTTAAQLNGTPHIGTVVTVLSVFAAARHNADVLDLPATVIFDALDNAPAEHVEIDGEIYTRTVGDLIDSGHLDRADRISGFERLLRWAADRSQVRYEFRPYSIYQRLTPVRTCLHAMASRLEDFRSIVAPADGIVRIRPRCPECRLMEKSAKNLSITAGDGVVHLDSLCPVHGCYRETIDISGTGGWYDANTPVRSIQKGFLLAAEGELYEACSVSVDGADWGGAWHAHVLAPALATLGIPAAEWPVSVFTPLVPDRSGGKLSKTLYVRYGAAYADLPEAFLNLDVLLDQHGDDALDALCTEVTRWAAEPRRLHRSYTVDYLADLIRIPANGPSLDRRSA
>CP025990.1|AUS79516.1|3578635_3579013_+|adenosylmethionine-decarboxylase
MIHAVYDITGCTIPNPEPAELLEAMRAAVARLGCTVLGELPVVFQPHGATCVLVLAESHLTVSTWPEHELAHVDLFTCRAETDPEKAIVPILAALGGETVHGQRIVRLGPAGIAAGSAPGGTGVR
>CP025990.1|AUS79517.1|3581656_3581971_+|hypothetical-protein
MDIDYEVRESVCDLAEADYVMMTDVIGILVDVGGVPWDQQISRAGRIAAGLVREGRITPGSLRGGTFTPWEGSRDEQAARIERETLEYEAEGREVIFGDIAWFA
>CP025990.1|AUS79518.1|3582054_3582369_+|hypothetical-protein
MDIDHEVRESLCDLAEDDYVMMAEIIGLIVRVGGVPWDQQISRAGRIAAGLVREGRITPGSLRGNVFTPWEGSREDWAVRVERETREYEENGREMNLGDIAWFA
>CP025990.1|AUS79519.1|3582686_3583001_+|hypothetical-protein
MDIDQEVRESVCDLVEIDYVMMSDIIGALVNVGGVSADRQISRAGEIAAQLVREGKITPGELHRGVFQHWEGSREETASRIERETREYEKAGRDVDLGDIAWFA

Crispr_ID: CP025990_25

• CRISPR_ID: CP025990_25
• CRISPR_location: 3609263-3609960
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 11 spacers

Consensus repeat of CP025990_25

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGACGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT

spacers of CP025990_25

>25.1|3609291|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTCGACAGGGGGAGACCTGTGGATGAGAACGCG
>25.2|3609352|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTACTCACGGACAGCATGGCGCGCTTCGCGAGA
>25.3|3609413|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GATGGCCTCTTGGGCGGCCCACGCCTCGTCCGC
>25.4|3609474|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CTGGACAAGATCATCTCCGGGTCCAACAGGAAC
>25.5|3609535|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTCCTATGTGGAGGGGGCGGCGGTCGGGTTCGC
>25.6|3609596|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TTGAGGCCCACCCACACCATGTCGTCCATTGCG
>25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCCGTTCTCACCCAGCGGCGGCGTCGTCGTC
>25.8|3609716|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCTGTAGGCAGATGTGCAACCTGGTGCTGCAAA
>25.9|3609777|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCGTATCCGGGGATGGCCGGCAGGGTCCCGGGG
>25.10|3609838|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTACTCCTCTCCGTCGGTCAGCCAGAGGACGTA
>25.11|3609899|33|CP025990|CRISPRCasFinder,CRT
CCGGGACAGTCAGGTCACGCGACCCGGAGGGGC

CRISPR arrays and Neighbor proteins around CP025990_25

CRISPR arrays

The CRISPR arrays of CP025990_25

>merge|CP025990|25|3609263-3609960|PILER-CR,CRISPRCasFinder,CRT
GGAACAGCCCCGCGTGCACGGGGAGGACGTCGACAGGGGGAGACCTGTGGATGAGAACGCGGGAACAGCCCCGCGTGCGCGGGGAGGACGTACTCACGGACAGCATGGCGCGCTTCGCGAGAGGAACAGCCCCGCGTGCGCGGGGAGGACGATGGCCTCTTGGGCGGCCCACGCCTCGTCCGCGGAACAGCCCCGCGTGCGCGGGGAGGACCTGGACAAGATCATCTCCGGGTCCAACAGGAACGGAACAGCCCCGCGTGCGCGGGGAGGACGTCCTATGTGGAGGGGGCGGCGGTCGGGTTCGCGGAACAGCCCTGCGTGCGCGGGGAGGACTTGAGGCCCACCCACACCATGTCGTCCATTGCGGGAACAGCCCCGCGTGCGCGGGGAGGACTCCGTTCTCACCCAGCGGCGGCGTCGTCGTCGGAACAGCCCCGCGTGCGCGGGGAGGACCCTGTAGGCAGATGTGCAACCTGGTGCTGCAAAGGAACAGCCCCGCGTGCGCGGGGAGGACCCGTATCCGGGGATGGCCGGCAGGGTCCCGGGGGGAACAGCCCCGCGTGCGCGGGGAGGACGTACTCCTCTCCGTCGGTCAGCCAGAGGACGTAGGAACAGCCCCGCGTGCGCGGGGAGGACCCGGGACAGTCAGGTCACGCGACCCGGAGGGGCGGAACAGCCCCGCGTGCGCGGGGAGGACA

>CP025990|25|19|3609263-3609898|PILER-CR
GGAACAGCCCCGCGTGCACGGGGAGGAC	GTCGACAGGGGGAGACCTGTGGATGAGAACGCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTACTCACGGACAGCATGGCGCGCTTCGCGAGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GATGGCCTCTTGGGCGGCCCACGCCTCGTCCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CTGGACAAGATCATCTCCGGGTCCAACAGGAAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTCCTATGTGGAGGGGGCGGCGGTCGGGTTCGC
GGAACAGCCCTGCGTGCGCGGGGAGGAC	TTGAGGCCCACCCACACCATGTCGTCCATTGCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCGTTCTCACCCAGCGGCGGCGTCGTCGTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCTGTAGGCAGATGTGCAACCTGGTGCTGCAAA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGTATCCGGGGATGGCCGGCAGGGTCCCGGGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTACTCCTCTCCGTCGGTCAGCCAGAGGACGTA
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|25|24|3609263-3609960|CRISPRCasFinder
GGAACAGCCCCGCGTGCACGGGGAGGAC	GTCGACAGGGGGAGACCTGTGGATGAGAACGCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTACTCACGGACAGCATGGCGCGCTTCGCGAGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GATGGCCTCTTGGGCGGCCCACGCCTCGTCCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CTGGACAAGATCATCTCCGGGTCCAACAGGAAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTCCTATGTGGAGGGGGCGGCGGTCGGGTTCGC
GGAACAGCCCTGCGTGCGCGGGGAGGAC	TTGAGGCCCACCCACACCATGTCGTCCATTGCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCGTTCTCACCCAGCGGCGGCGTCGTCGTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCTGTAGGCAGATGTGCAACCTGGTGCTGCAAA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGTATCCGGGGATGGCCGGCAGGGTCCCGGGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTACTCCTCTCCGTCGGTCAGCCAGAGGACGTA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGGGACAGTCAGGTCACGCGACCCGGAGGGGC
GGAACAGCCCCGCGTGCGCGGGGAGGACA

>CP025990|25|19|3609263-3609959|CRT
GGAACAGCCCCGCGTGCACGGGGAGGAC	GTCGACAGGGGGAGACCTGTGGATGAGAACGCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTACTCACGGACAGCATGGCGCGCTTCGCGAGA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GATGGCCTCTTGGGCGGCCCACGCCTCGTCCGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CTGGACAAGATCATCTCCGGGTCCAACAGGAAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTCCTATGTGGAGGGGGCGGCGGTCGGGTTCGC
GGAACAGCCCTGCGTGCGCGGGGAGGAC	TTGAGGCCCACCCACACCATGTCGTCCATTGCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCGTTCTCACCCAGCGGCGGCGTCGTCGTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCTGTAGGCAGATGTGCAACCTGGTGCTGCAAA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGTATCCGGGGATGGCCGGCAGGGTCCCGGGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GTACTCCTCTCCGTCGGTCAGCCAGAGGACGTA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCGGGACAGTCAGGTCACGCGACCCGGAGGGGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79537.1|3612789_3612972_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81790.1|3606271_3606883_+|RimJ/RimL-family-protein-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
CP025990.1|AUS81789.1|3596980_3597208_+|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
CP025990.1|AUS79542.1|3623938_3624904_-|amidohydrolase	unknown	unknown	gnl|CDD|368185
CP025990.1|AUS79536.1|3612116_3612671_+|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79535.1|3610825_3611182_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79532.1|3605371_3606220_+|hypothetical-protein	unknown	unknown	gnl|CDD|274042
CP025990.1|AUS79539.1|3620352_3620574_-|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
CP025990.1|AUS79543.1|3625225_3625957_-|chitinase	unknown	unknown	gnl|CDD|381595
CP025990.1|AUS79527.1|3593471_3594494_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|275336
CP025990.1|AUS79528.1|3594609_3595737_-|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|237363
CP025990.1|AUS79541.1|3623362_3623860_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79530.1|3598896_3599712_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
CP025990.1|AUS79531.1|3603584_3603905_+|Cro/Cl-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379188
CP025990.1|AUS79534.1|3608278_3608695_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79540.1|3622312_3623212_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
CP025990.1|AUS79533.1|3607036_3608269_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79529.1|3597467_3598805_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235687
CP025990.1|AUS79538.1|3616284_3619761_-|serine-protease	unknown	unknown	gnl|CDD|173812
CP025990.1|AUS81791.1|3611223_3611778_+|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79538.1|3616284_3619761_-|serine-protease	gnl|CDD|173812	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	9.1338e-70
CP025990.1|AUS81790.1|3606271_3606883_+|RimJ/RimL-family-protein-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	8.18047e-22
CP025990.1|AUS81789.1|3596980_3597208_+|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	2.10846e-32
CP025990.1|AUS79542.1|3623938_3624904_-|amidohydrolase	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	2.36825e-28
CP025990.1|AUS79536.1|3612116_3612671_+|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.73928e-13
CP025990.1|AUS79532.1|3605371_3606220_+|hypothetical-protein	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	0.000157649
CP025990.1|AUS79539.1|3620352_3620574_-|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	1.05205e-09
CP025990.1|AUS79543.1|3625225_3625957_-|chitinase	gnl|CDD|381595	cd00325, chitinase_GH19, Glycoside hydrolase family 19, chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Glycoside hydrolase family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases, but they are smaller in size due to certain deletions. Despite lacking any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the prokaryotic/eukaryotic divergence.	1.43259e-83
CP025990.1|AUS79527.1|3593471_3594494_-|SAM-dependent-methyltransferase	gnl|CDD|275336	TIGR04543, 2-ketoarginine_methyltransferase, 2-ketoarginine methyltransferase. This SAM-dependent C-methyltransferase performs the middle step of a three step conversion from arginine to beta-methylarginine. It performs a C-methylation at position 3 of 5-guanidino-2-oxopentanoic acid (keto-arginine). An aminotransferase converts arginine to 5-guanidino-2-oxopentanoic acid, and later converts 5-guanidino-3-methyl-2-oxopentanoic acid to beta-methylarginine.	3.33429e-12
CP025990.1|AUS79528.1|3594609_3595737_-|branched-chain-amino-acid-aminotransferase	gnl|CDD|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	7.01573e-175
CP025990.1|AUS79530.1|3598896_3599712_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.36626e-29
CP025990.1|AUS79531.1|3603584_3603905_+|Cro/Cl-family-transcriptional-regulator	gnl|CDD|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.61249e-14
CP025990.1|AUS79540.1|3622312_3623212_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.39592e-20
CP025990.1|AUS79529.1|3597467_3598805_+|aspartate-aminotransferase-family-protein	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
CP025990.1|AUS81791.1|3611223_3611778_+|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	8.21016e-14

Protein sequences

>CP025990.1|AUS79534.1|3608278_3608695_-|hypothetical-protein
MVPQTMSRYSSIACGLWIAGPDEDMIVVDDTSSPLHREHTILHEVGHMLCGHQGTTLGRGLAGPSRATSQLVSDLLQDARDGSTRVLHREYYGDKAELEAETFAYLVWRRVGEQLLAPLGARGRLDSALAGRGGATHA
>CP025990.1|AUS79533.1|3607036_3608269_-|hypothetical-protein
MLNRDLVQSIVLGLIVAGCVIKLFHLRRSGENRPAIVGMCLGLMGLAVGLLLLDEAAGVIGSAELDEAVGPGVAYALRQIPIMIAAYGFRLFLIAWVWEPGRQRTLRMWLQTAIAGTVILARLLIGVVTPSGEIPAVWRSDWGQVPWSAAGMLLYAAYMGSTAIAVTRLTWLWARDAQTRRTTKIGLWLICAMAICGGIEALHKIGYFTAVAVVGHKPPYDQYAAEFVPIALGTACGAIGLALPLIANGVPAAIRTYRHRAARRGLWPLWSALTALRPGVVIPQHPRWLPTSWTRAWESVDLRKLDVKLYHRVIECWDVLVYLHGHLSSEVREREIQRAVAEGHGPERARSLGEAEMIRQAVDRARERRPFLAESERARPLAAHRTLAENVRWLRQVAAAWRRGATGRTR
>CP025990.1|AUS81790.1|3606271_3606883_+|RimJ/RimL-family-protein-N-acetyltransferase
MTSIWTGHKVRVRGIEPEDWQAFQHFDEHSAAMRNADMIQPPRSAAGYREWAAIQATQQTAGDEFLLAIEARADQTLVGSLSTNNVDQRAGRFSYGISIGHDHQRHGYATDAIPLLLTYMFGERRFHKCEVDIYAFNEASIALHRKIGFQTEGRLRDHEYFAGRHHDLVVMGLTIDEFAARHPLAEPHQHTQPTTHPDEPTSS
>CP025990.1|AUS79532.1|3605371_3606220_+|hypothetical-protein
MTADLRLWFEVMRHGHTSPPRSRPRTPKNIQAALRRAMPALHTWATAGHQHLREITRDDVLAILPGSGTPRHTMLSGLRSIFRLLKAHKRVFVNPTARIPVGRPSGNLPLPTPVDRIREALASDDPASASIAALVAFHALSPGQLRDLQLIDIHAGRLHLSDRTIPLAQPVRERLRAYLDYRTARWPSTANTHLFIHYRSANHLGPVQIEWLTHRLGLSAQALREDRILHEVHATGGDIRRLCDLFGLSVSGAERYTAVLDHPNINRANGLPESHIRPKGTA
>CP025990.1|AUS79531.1|3603584_3603905_+|Cro/Cl-family-transcriptional-regulator
MRWNLRMKAAEAGIWKSTELRRRLADAGLEISAGKMSALWTGTPTTIRLDDLDVICAVLECEPTDLLIREPEKVAERKPRKTAEATGGTSTVVAPQFGRHRSLPPA
>CP025990.1|AUS79530.1|3598896_3599712_+|alpha/beta-hydrolase
MSTADINGIRVQYEDVGDGEPVVLVMGSGSTGRAWHLHQVPALVSAGYRVITFDNRGSSASTRDLVGFTVEDLVADTVRLIEHLGLGPCRLVGTSMGAHVVQELLVTRADLVSQAVLMATRGRTDVMRRFAALAEREQVDSGVELPARYAASIRAMQVLSPATLNDDRKCQDWLDIFEMVPAEHSKGYRAQLDLDIIPDRLAAYRSITTPTLVIGFADDLVLPPHLCREVADAIPAARYVELADSGHYGYLERPEAVNAELVSFFAERRVR
>CP025990.1|AUS79529.1|3597467_3598805_+|aspartate-aminotransferase-family-protein
MSDAAEISAAERDHVFHSWSAQGSVNPLPIAGGEGCWFWDHDGNRYLDLASQLVNVNLGHQHPRVVAAIRDQAERLCTVAPQFGNETRSTLARLIVERAPGDLDAVFFTNGGTEAVEHAVRMARLHTGRHKVLSAYRSYHGATAGSITLTGDPRRWANEPGVPGVARFFGPHLYRSAFHATTEEEESDRALRHLAEVIQFEGPDTVAAVLLEPVVGTNGVLVPPPGYLAGVRELCDRHGILLISDEVMVGFGRVGEWFAVDAWDVTPDLITFAKGVNSGYVPLGGVVISRRIADTFTDRAYPGGLTYSGHPLACAAGVASIQVFEETDLLRRVRRLGSEVVEPALRELAERHPSVGHVRGRGLFWAVELVRDRDTREPLVPFNASGADAAPMNQLAAAMRANGVWPFVNMNRLHLAPPLVISEEELALGLKALDEALAVTDALVG
>CP025990.1|AUS81789.1|3596980_3597208_+|MbtH-family-protein
MTNPFEDPDATYLVLINDEGQYSLWPSFAEVPGGWTVVVTETDRQSCLDYIEENWTDMRPRSLVREMEGAGSSGD
>CP025990.1|AUS79528.1|3594609_3595737_-|branched-chain-amino-acid-aminotransferase
MNHRTTTPAAAAPFDVAHVPPADRLTTAVRTDRMRHPGFGRVLTEHMVTIRWTEDAGWHEARLRPYQALEFDPATVGIHYGQIVFEGLKAYSLADGRVGIFRPDAAARRLQRSATRLAMPEMPTALFTSALTELVRADRAWVPAEVGKSLYLRPVLMATEADLDLRPAREYLFLLIAFVTDNFFPGELRPRTVWVCEDHVRAAPGGTGEAKTPGNYAASLLAQEQARERGCDQVVWLDAVERRWVEEMGGMNLFFAVGPEEAPRLLTPPLRGTILPGVTRDSLITIASDLGWSTSEEPISVEQWRRWADGGSLREVFACGTAAVVTPVGTVRSAAGDWTVNGGRAGPLAARLRTALLDVQHGLVPDRHGWMVPVG
>CP025990.1|AUS79527.1|3593471_3594494_-|SAM-dependent-methyltransferase
MTVTDEVPTTVAVGPREAAADAAGAAALLEIGDRLGLLPHIDQGQSVTAARLAAEADLPEEGVANYLEAMSSAGIMVDSPDGEGGLRVADDFDQIQYESGYLSWAMNANRPFVNNAVEFLRAPLDSRAKYPRDGRQVAVSSEWMGSKGFYPVALQTILDARPSRVVDLGAGTARLLIEVMLQLPETTAVALDLDGPSCEEAVLAAERAGVADRLTVIEAPIQSVAEDPTPVLGADVVHAGFVFHDMMPDEEHVADAVLANCREGLRPGGMMAITDAVPYVKNIRERRFSAIVSYYHKQFMRRRLLSEEEWTAKLSGAGFSSVECVPHRFPTGRLFRATKA
>CP025990.1|AUS79535.1|3610825_3611182_+|hypothetical-protein
MLIHSAAAAAGKVSIDPESAESMARKIDAIAERAVDRRRRVDRLNQNVPLGSSPVALQMSAQTRLSAAGTPQSAKENLELYIEALTELAAAIRASARRTQAADEQTAAEFNRLGEDEA
>CP025990.1|AUS81791.1|3611223_3611778_+|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEKITALGFDPESASFDDVGLSYACSYRWPSGGLTLMAIDLNWKRSVDQLDLTNYTSEETSVGSLRALRIVDKPESEHCQMSLALSSQAHVTISVHYAGTAEQACDLAEQVAAAVEPELPRSSG
>CP025990.1|AUS79536.1|3612116_3612671_+|DUF3558-domain-containing-protein
MGLLSACTSAEQGTAVAVGPTVGSSLPGSADPSVGGGPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESATFDDVGLSYDCRYRFPGGARPVLTIHLNWMRGVDQLNLTNYTVEEISVGPLRALRVIDKPAAQHCQISMDLSEQAHVSAVVDYAETLEEACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS79537.1|3612789_3612972_+|hypothetical-protein
MCGVRGRWRPVVCFYDGPQGTAHIEALTELSAAVRASARRIQAVDEQNVSAFGWLGGDEA
>CP025990.1|AUS79538.1|3616284_3619761_-|serine-protease
MRSPGAVANPLRFSSDRPPPVTVVLFCRSDHSSVYCGCFCSSLEQGWRSVPLVLIGRRGNDRKWEFMGARRRRAAGSALLLTAGLALGGATTATAGTPDLGVRAEAPGTFETLTLVTGDHLHVRQLGGGRLATTVRPAPGREHVQFLHRTVGGRTTIVPSDAERLVRTGVLDQRLFDVHGLLEQGFGDAGPLPLIVAYQRGNDPGAGVSVFSGEASTGRVLTSVNAVAVHPGEDSADVVWAELTNDATEPRAFSGGVDRVWLNGRARVLDEESNAQVGAPEVWEAGYTGAGVTVAVLDGGYDPDHPDLVDAVVEAVDFTDPAGTAADGFGHGTHVAATVAGRGAASDGAHRGVAPDADLVVGKVCDDSGYCPEDAIIAGMEWAAAGDAVAVNLSLGIGPTDGTDPMSVAVDTLTEDTGTLFVAAAGNDGWDMTVSSPAAADAALAVGSVTKSDELSDFSSRGPRVGDWAVKPEIAAPGSGIVSARAAGTAMGSLVDEHHTSADGTSMASPHVAGAVALLAEANPEWRAREFRAALMAAAEPLAGVPVSGQGAGRLDVARAMRQSVVAEPSSLSLGNFTWPRDGEEPAAGTVTYRNTGEEDLILDLAVDLVTEDGEAVPADLVELSVSDLLVPAGGAAGATVTVDVAHGTTGYLSGTLRATAEGGVAVSTPVGLHLEPESYDLGVDVLDRDGRSTSRAALLVEDADTGYSYYLEADGNGDYAVRLPGGTYNLLARIGDDTSDEYTYVVERAVQLTSDARVTVDATPAVPIEVRTERPSELRYHDSALLSEDRQSSLGALGFGTKQKYAVPARGSFALNYKPTLVSSSEDEYRYHLATQFVDEIPAEPVLAPRDEELAEVTSRYQAQGVAAAGLRTVVGQLVDDWSLFGFGLPVDVPGSGTDYHSVTDDVEWREYLGFQDDLGENYEETGRVSVYAAGAASIRWNTAPVTILGEGRRTGDDLTFSPRYFVTSDTDQYYGYGSADVFAGELTLSDEQGVLASSDEYGFLRAPVPSEPGMYTLEATATRNVEWSMLGTSARARWTFRSENPGTEGPTGLPLMGVRFTSVATVDDPLGVLPGNGEHAFAVTVEDTAGGIAELAVEYSVDDGETWEPLEVVDGVVSVVHPAEGFVSLRARAADSEGNSVEQAVIRSYQVGPSTR
>CP025990.1|AUS79539.1|3620352_3620574_-|DUF3618-domain-containing-protein
MARDPDEIEREIEDARTALAGTLDELGSKANPQRFIESGKASARERLADPRVKYSLMAIGALIAFALLRRLFR
>CP025990.1|AUS79540.1|3622312_3623212_-|alpha/beta-hydrolase
MVEERHVEGSPRLVVRDHGGQRTGRDIVVLHGFGGNALNWEAFVPLLTSRHRVVACDLRCHGRSGDGAWDWEALVDDVDRVVADLGAERPVVVGHSLGGAVATLWAGHHPEAAGAVNIDGFRGVETEERHYLGIDPDELAARLAELSADFAAQAAALAEPLQPEAVEVARAQHRTAGGDRAVEAFDRGLAVRDGLTVARPDPGTVAAFRTWMAALDLTEPLAAARCPVLVLTATRDLPEADRYADLLAAWRRGVERDLDSVARTNPRVRVEHVAASHAMVLESPDIIAGHVLDFLDILG
>CP025990.1|AUS79541.1|3623362_3623860_+|hypothetical-protein
MTLENALRDQLVALVDARCVDPLEILLEDADTADALRHRVRERAPAWARAMVAGDDAEAILAITRVIATLYPGDGPFDPPADWWRTPLGTITARRVGHPSAHALSYPVAGAMLGISRQGVHDLVNRGKLERHPDGGVTASSVRDRSRANALPQAPHHPGSGADRS
>CP025990.1|AUS79542.1|3623938_3624904_-|amidohydrolase
MSGGRIDLHAHYLPDFYREALAESGHGRRAAISSLPEWDEQLALRTMDRLGVRTAMLSVSTPGVHFGDADRAVDLARRVNEEGARLVREHPGRFGFFASLPLPEVEPAVAELRHAFDVLGADGVILQSNHHGLYLGDERLEPVYAEVAARGSVVFVHPAMPFVAEHLALGYPQPALEFPFDTTRSVVDLVLSGVLERHPDLRVVVSHAGAVLPVLANRVDLLVPMLAVPKGRSTPSLRAAMRRLHFDLAGAPVPELLGALLSLADPDRLHYGSDYPFFPAALGRELADRLAETPLLDGELRRAVFEDNAVRLFPRLASPTS
>CP025990.1|AUS79543.1|3625225_3625957_-|chitinase
MSITRLVKAVATVAAVSALLVSAPMTTSTATAEPAAPQGFVVSEAQFNQMFPNRNPFYTYQGLTAALSSYPGFTNTGDETTRRREAAAFLANASHETGGLVHIVEQNEANYPHYCDWSQPYGCPAGQAAYYGRGPIQLSWNFNYKAAGDALGLDLLGNPWLVQNDASVAWRTALWYWNTQSGPGTMTPHHAIVNGHGFGETIRSINGALECDGANPGQVQSRVDTYQRFTQILGTTPGGNLYC

Crispr_ID: CP025990_26

• CRISPR_ID: CP025990_26
• CRISPR_location: 3610277-3610789
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of CP025990_26

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGNNA	CRT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGACGAC	CRISPRCasFinder

spacers of CP025990_26

>26.1|3610301|33|CP025990|CRT
CGACGTGGCGGGTTGACGGACGGCCGCCACCTG
>26.2|3610358|37|CP025990|CRT
GGACTTCGACGGGCAGCGGCTGTTTCTCACCCAGTCG
>26.3|3610419|38|CP025990|CRT
GGACCCTGGCGGCCTTCACGGCGTCGGCGTAGCAGTGC
>26.4|3610481|37|CP025990|CRT
GGACCGCACGGGCCGTGCGGCGGGTGGCGTGGTGGAG
>26.5|3610542|36|CP025990|CRT
GGACGAACGTTAAGGACCCAAGAGGGGGGTAGACAT
>26.6|3610602|38|CP025990|CRT
GGACGCTGAGGTGCGGGGAGGGTTCACCGCGGACGACG
>26.7|3610664|37|CP025990|CRT
CGACCTTGACCACTGACGAAGCCAGGTCAGCACGGAA
>26.8|3610725|37|CP025990|CRT
CGACTGAGGTCCACGGCGGGCTACTCGGATACCACAC
>26.9|3610362|33|CP025990|PILER-CR,CRISPRCasFinder
TTCGACGGGCAGCGGCTGTTTCTCACCCAGTCG
>26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder
CCTGGCGGCCTTCACGGCGTCGGCGTAGCAGTGC
>26.11|3610485|33|CP025990|PILER-CR,CRISPRCasFinder
CGCACGGGCCGTGCGGCGGGTGGCGTGGTGGAG
>26.12|3610546|32|CP025990|PILER-CR,CRISPRCasFinder
GAACGTTAAGGACCCAAGAGGGGGGTAGACAT
>26.13|3610606|34|CP025990|PILER-CR,CRISPRCasFinder
GCTGAGGTGCGGGGAGGGTTCACCGCGGACGACG
>26.14|3610668|33|CP025990|PILER-CR,CRISPRCasFinder
CTTGACCACTGACGAAGCCAGGTCAGCACGGAA
>26.15|3610729|33|CP025990|PILER-CR,CRISPRCasFinder
TGAGGTCCACGGCGGGCTACTCGGATACCACAC

CRISPR arrays and Neighbor proteins around CP025990_26

CRISPR arrays

The CRISPR arrays of CP025990_26

>merge|CP025990|26|3610277-3610789|CRT,PILER-CR,CRISPRCasFinder
CTCGGGACCAGCTTCGCGCGGGGACGACGTGGCGGGTTGACGGACGGCCGCCACCTGGGAACAGCCCCACGTGCGCGGGGAGGACTTCGACGGGCAGCGGCTGTTTCTCACCCAGTCGGGAACAGCCCCGCGTGCGCGGGGAGGACCCTGGCGGCCTTCACGGCGTCGGCGTAGCAGTGCGGAACAGCCCCGCGTGCGCGGGGAGGACCGCACGGGCCGTGCGGCGGGTGGCGTGGTGGAGGGAACAGCCCCGCGTGCGCGGGGAGGACGAACGTTAAGGACCCAAGAGGGGGGTAGACATGGAACAGCCCCGCGTGCGCGGGGAGGACGCTGAGGTGCGGGGAGGGTTCACCGCGGACGACGGGAACAGCCCCGCGTGCGCGGGGACGACCTTGACCACTGACGAAGCCAGGTCAGCACGGAAGGAACAGCCCCGCGTGCGCGGGGACGACTGAGGTCCACGGCGGGCTACTCGGATACCACACGGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|26|20|3610277-3610785|CRT
CTCGGGACCAGCTTCGCGCGGGGA	CGACGTGGCGGGTTGACGGACGGCCGCCACCTG
GGAACAGCCCCACGTGCGCGGGGA	GGACTTCGACGGGCAGCGGCTGTTTCTCACCCAGTCG
GGAACAGCCCCGCGTGCGCGGGGA	GGACCCTGGCGGCCTTCACGGCGTCGGCGTAGCAGTGC
GGAACAGCCCCGCGTGCGCGGGGA	GGACCGCACGGGCCGTGCGGCGGGTGGCGTGGTGGAG
GGAACAGCCCCGCGTGCGCGGGGA	GGACGAACGTTAAGGACCCAAGAGGGGGGTAGACAT
GGAACAGCCCCGCGTGCGCGGGGA	GGACGCTGAGGTGCGGGGAGGGTTCACCGCGGACGACG
GGAACAGCCCCGCGTGCGCGGGGA	CGACCTTGACCACTGACGAAGCCAGGTCAGCACGGAA
GGAACAGCCCCGCGTGCGCGGGGA	CGACTGAGGTCCACGGCGGGCTACTCGGATACCACAC
GGAACAGCCCCGCGTGCGCGGGGA

>CP025990|26|20|3610334-3610789|PILER-CR
GGAACAGCCCCACGTGCGCGGGGAGGAC	TTCGACGGGCAGCGGCTGTTTCTCACCCAGTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCTGGCGGCCTTCACGGCGTCGGCGTAGCAGTGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGCACGGGCCGTGCGGCGGGTGGCGTGGTGGAG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GAACGTTAAGGACCCAAGAGGGGGGTAGACAT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCTGAGGTGCGGGGAGGGTTCACCGCGGACGACG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CTTGACCACTGACGAAGCCAGGTCAGCACGGAA
GGAACAGCCCCGCGTGCGCGGGGACGAC	TGAGGTCCACGGCGGGCTACTCGGATACCACAC
GGAACAGCCCCGCGTGCGCGGGGACGAC

>CP025990|26|25|3610334-3610789|CRISPRCasFinder
GGAACAGCCCCACGTGCGCGGGGAGGAC	TTCGACGGGCAGCGGCTGTTTCTCACCCAGTCG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCTGGCGGCCTTCACGGCGTCGGCGTAGCAGTGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGCACGGGCCGTGCGGCGGGTGGCGTGGTGGAG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GAACGTTAAGGACCCAAGAGGGGGGTAGACAT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCTGAGGTGCGGGGAGGGTTCACCGCGGACGACG
GGAACAGCCCCGCGTGCGCGGGGACGAC	CTTGACCACTGACGAAGCCAGGTCAGCACGGAA
GGAACAGCCCCGCGTGCGCGGGGACGAC	TGAGGTCCACGGCGGGCTACTCGGATACCACAC
GGAACAGCCCCGCGTGCGCGGGGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79537.1|3612789_3612972_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81790.1|3606271_3606883_+|RimJ/RimL-family-protein-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
CP025990.1|AUS81789.1|3596980_3597208_+|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
CP025990.1|AUS79542.1|3623938_3624904_-|amidohydrolase	unknown	unknown	gnl|CDD|368185
CP025990.1|AUS79536.1|3612116_3612671_+|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS79535.1|3610825_3611182_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79532.1|3605371_3606220_+|hypothetical-protein	unknown	unknown	gnl|CDD|274042
CP025990.1|AUS79539.1|3620352_3620574_-|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
CP025990.1|AUS79543.1|3625225_3625957_-|chitinase	unknown	unknown	gnl|CDD|381595
CP025990.1|AUS79527.1|3593471_3594494_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|275336
CP025990.1|AUS79528.1|3594609_3595737_-|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|237363
CP025990.1|AUS79541.1|3623362_3623860_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79530.1|3598896_3599712_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
CP025990.1|AUS79531.1|3603584_3603905_+|Cro/Cl-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379188
CP025990.1|AUS79534.1|3608278_3608695_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79540.1|3622312_3623212_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
CP025990.1|AUS79533.1|3607036_3608269_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79529.1|3597467_3598805_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235687
CP025990.1|AUS79538.1|3616284_3619761_-|serine-protease	unknown	unknown	gnl|CDD|173812
CP025990.1|AUS81791.1|3611223_3611778_+|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79538.1|3616284_3619761_-|serine-protease	gnl|CDD|173812	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	9.1338e-70
CP025990.1|AUS81790.1|3606271_3606883_+|RimJ/RimL-family-protein-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	8.18047e-22
CP025990.1|AUS81789.1|3596980_3597208_+|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	2.10846e-32
CP025990.1|AUS79542.1|3623938_3624904_-|amidohydrolase	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	2.36825e-28
CP025990.1|AUS79536.1|3612116_3612671_+|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.73928e-13
CP025990.1|AUS79532.1|3605371_3606220_+|hypothetical-protein	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	0.000157649
CP025990.1|AUS79539.1|3620352_3620574_-|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	1.05205e-09
CP025990.1|AUS79543.1|3625225_3625957_-|chitinase	gnl|CDD|381595	cd00325, chitinase_GH19, Glycoside hydrolase family 19, chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Glycoside hydrolase family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases, but they are smaller in size due to certain deletions. Despite lacking any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the prokaryotic/eukaryotic divergence.	1.43259e-83
CP025990.1|AUS79527.1|3593471_3594494_-|SAM-dependent-methyltransferase	gnl|CDD|275336	TIGR04543, 2-ketoarginine_methyltransferase, 2-ketoarginine methyltransferase. This SAM-dependent C-methyltransferase performs the middle step of a three step conversion from arginine to beta-methylarginine. It performs a C-methylation at position 3 of 5-guanidino-2-oxopentanoic acid (keto-arginine). An aminotransferase converts arginine to 5-guanidino-2-oxopentanoic acid, and later converts 5-guanidino-3-methyl-2-oxopentanoic acid to beta-methylarginine.	3.33429e-12
CP025990.1|AUS79528.1|3594609_3595737_-|branched-chain-amino-acid-aminotransferase	gnl|CDD|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	7.01573e-175
CP025990.1|AUS79530.1|3598896_3599712_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.36626e-29
CP025990.1|AUS79531.1|3603584_3603905_+|Cro/Cl-family-transcriptional-regulator	gnl|CDD|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.61249e-14
CP025990.1|AUS79540.1|3622312_3623212_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.39592e-20
CP025990.1|AUS79529.1|3597467_3598805_+|aspartate-aminotransferase-family-protein	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
CP025990.1|AUS81791.1|3611223_3611778_+|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	8.21016e-14

Protein sequences

>CP025990.1|AUS79534.1|3608278_3608695_-|hypothetical-protein
MVPQTMSRYSSIACGLWIAGPDEDMIVVDDTSSPLHREHTILHEVGHMLCGHQGTTLGRGLAGPSRATSQLVSDLLQDARDGSTRVLHREYYGDKAELEAETFAYLVWRRVGEQLLAPLGARGRLDSALAGRGGATHA
>CP025990.1|AUS79533.1|3607036_3608269_-|hypothetical-protein
MLNRDLVQSIVLGLIVAGCVIKLFHLRRSGENRPAIVGMCLGLMGLAVGLLLLDEAAGVIGSAELDEAVGPGVAYALRQIPIMIAAYGFRLFLIAWVWEPGRQRTLRMWLQTAIAGTVILARLLIGVVTPSGEIPAVWRSDWGQVPWSAAGMLLYAAYMGSTAIAVTRLTWLWARDAQTRRTTKIGLWLICAMAICGGIEALHKIGYFTAVAVVGHKPPYDQYAAEFVPIALGTACGAIGLALPLIANGVPAAIRTYRHRAARRGLWPLWSALTALRPGVVIPQHPRWLPTSWTRAWESVDLRKLDVKLYHRVIECWDVLVYLHGHLSSEVREREIQRAVAEGHGPERARSLGEAEMIRQAVDRARERRPFLAESERARPLAAHRTLAENVRWLRQVAAAWRRGATGRTR
>CP025990.1|AUS81790.1|3606271_3606883_+|RimJ/RimL-family-protein-N-acetyltransferase
MTSIWTGHKVRVRGIEPEDWQAFQHFDEHSAAMRNADMIQPPRSAAGYREWAAIQATQQTAGDEFLLAIEARADQTLVGSLSTNNVDQRAGRFSYGISIGHDHQRHGYATDAIPLLLTYMFGERRFHKCEVDIYAFNEASIALHRKIGFQTEGRLRDHEYFAGRHHDLVVMGLTIDEFAARHPLAEPHQHTQPTTHPDEPTSS
>CP025990.1|AUS79532.1|3605371_3606220_+|hypothetical-protein
MTADLRLWFEVMRHGHTSPPRSRPRTPKNIQAALRRAMPALHTWATAGHQHLREITRDDVLAILPGSGTPRHTMLSGLRSIFRLLKAHKRVFVNPTARIPVGRPSGNLPLPTPVDRIREALASDDPASASIAALVAFHALSPGQLRDLQLIDIHAGRLHLSDRTIPLAQPVRERLRAYLDYRTARWPSTANTHLFIHYRSANHLGPVQIEWLTHRLGLSAQALREDRILHEVHATGGDIRRLCDLFGLSVSGAERYTAVLDHPNINRANGLPESHIRPKGTA
>CP025990.1|AUS79531.1|3603584_3603905_+|Cro/Cl-family-transcriptional-regulator
MRWNLRMKAAEAGIWKSTELRRRLADAGLEISAGKMSALWTGTPTTIRLDDLDVICAVLECEPTDLLIREPEKVAERKPRKTAEATGGTSTVVAPQFGRHRSLPPA
>CP025990.1|AUS79530.1|3598896_3599712_+|alpha/beta-hydrolase
MSTADINGIRVQYEDVGDGEPVVLVMGSGSTGRAWHLHQVPALVSAGYRVITFDNRGSSASTRDLVGFTVEDLVADTVRLIEHLGLGPCRLVGTSMGAHVVQELLVTRADLVSQAVLMATRGRTDVMRRFAALAEREQVDSGVELPARYAASIRAMQVLSPATLNDDRKCQDWLDIFEMVPAEHSKGYRAQLDLDIIPDRLAAYRSITTPTLVIGFADDLVLPPHLCREVADAIPAARYVELADSGHYGYLERPEAVNAELVSFFAERRVR
>CP025990.1|AUS79529.1|3597467_3598805_+|aspartate-aminotransferase-family-protein
MSDAAEISAAERDHVFHSWSAQGSVNPLPIAGGEGCWFWDHDGNRYLDLASQLVNVNLGHQHPRVVAAIRDQAERLCTVAPQFGNETRSTLARLIVERAPGDLDAVFFTNGGTEAVEHAVRMARLHTGRHKVLSAYRSYHGATAGSITLTGDPRRWANEPGVPGVARFFGPHLYRSAFHATTEEEESDRALRHLAEVIQFEGPDTVAAVLLEPVVGTNGVLVPPPGYLAGVRELCDRHGILLISDEVMVGFGRVGEWFAVDAWDVTPDLITFAKGVNSGYVPLGGVVISRRIADTFTDRAYPGGLTYSGHPLACAAGVASIQVFEETDLLRRVRRLGSEVVEPALRELAERHPSVGHVRGRGLFWAVELVRDRDTREPLVPFNASGADAAPMNQLAAAMRANGVWPFVNMNRLHLAPPLVISEEELALGLKALDEALAVTDALVG
>CP025990.1|AUS81789.1|3596980_3597208_+|MbtH-family-protein
MTNPFEDPDATYLVLINDEGQYSLWPSFAEVPGGWTVVVTETDRQSCLDYIEENWTDMRPRSLVREMEGAGSSGD
>CP025990.1|AUS79528.1|3594609_3595737_-|branched-chain-amino-acid-aminotransferase
MNHRTTTPAAAAPFDVAHVPPADRLTTAVRTDRMRHPGFGRVLTEHMVTIRWTEDAGWHEARLRPYQALEFDPATVGIHYGQIVFEGLKAYSLADGRVGIFRPDAAARRLQRSATRLAMPEMPTALFTSALTELVRADRAWVPAEVGKSLYLRPVLMATEADLDLRPAREYLFLLIAFVTDNFFPGELRPRTVWVCEDHVRAAPGGTGEAKTPGNYAASLLAQEQARERGCDQVVWLDAVERRWVEEMGGMNLFFAVGPEEAPRLLTPPLRGTILPGVTRDSLITIASDLGWSTSEEPISVEQWRRWADGGSLREVFACGTAAVVTPVGTVRSAAGDWTVNGGRAGPLAARLRTALLDVQHGLVPDRHGWMVPVG
>CP025990.1|AUS79527.1|3593471_3594494_-|SAM-dependent-methyltransferase
MTVTDEVPTTVAVGPREAAADAAGAAALLEIGDRLGLLPHIDQGQSVTAARLAAEADLPEEGVANYLEAMSSAGIMVDSPDGEGGLRVADDFDQIQYESGYLSWAMNANRPFVNNAVEFLRAPLDSRAKYPRDGRQVAVSSEWMGSKGFYPVALQTILDARPSRVVDLGAGTARLLIEVMLQLPETTAVALDLDGPSCEEAVLAAERAGVADRLTVIEAPIQSVAEDPTPVLGADVVHAGFVFHDMMPDEEHVADAVLANCREGLRPGGMMAITDAVPYVKNIRERRFSAIVSYYHKQFMRRRLLSEEEWTAKLSGAGFSSVECVPHRFPTGRLFRATKA
>CP025990.1|AUS79535.1|3610825_3611182_+|hypothetical-protein
MLIHSAAAAAGKVSIDPESAESMARKIDAIAERAVDRRRRVDRLNQNVPLGSSPVALQMSAQTRLSAAGTPQSAKENLELYIEALTELAAAIRASARRTQAADEQTAAEFNRLGEDEA
>CP025990.1|AUS81791.1|3611223_3611778_+|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEKITALGFDPESASFDDVGLSYACSYRWPSGGLTLMAIDLNWKRSVDQLDLTNYTSEETSVGSLRALRIVDKPESEHCQMSLALSSQAHVTISVHYAGTAEQACDLAEQVAAAVEPELPRSSG
>CP025990.1|AUS79536.1|3612116_3612671_+|DUF3558-domain-containing-protein
MGLLSACTSAEQGTAVAVGPTVGSSLPGSADPSVGGGPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESATFDDVGLSYDCRYRFPGGARPVLTIHLNWMRGVDQLNLTNYTVEEISVGPLRALRVIDKPAAQHCQISMDLSEQAHVSAVVDYAETLEEACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS79537.1|3612789_3612972_+|hypothetical-protein
MCGVRGRWRPVVCFYDGPQGTAHIEALTELSAAVRASARRIQAVDEQNVSAFGWLGGDEA
>CP025990.1|AUS79538.1|3616284_3619761_-|serine-protease
MRSPGAVANPLRFSSDRPPPVTVVLFCRSDHSSVYCGCFCSSLEQGWRSVPLVLIGRRGNDRKWEFMGARRRRAAGSALLLTAGLALGGATTATAGTPDLGVRAEAPGTFETLTLVTGDHLHVRQLGGGRLATTVRPAPGREHVQFLHRTVGGRTTIVPSDAERLVRTGVLDQRLFDVHGLLEQGFGDAGPLPLIVAYQRGNDPGAGVSVFSGEASTGRVLTSVNAVAVHPGEDSADVVWAELTNDATEPRAFSGGVDRVWLNGRARVLDEESNAQVGAPEVWEAGYTGAGVTVAVLDGGYDPDHPDLVDAVVEAVDFTDPAGTAADGFGHGTHVAATVAGRGAASDGAHRGVAPDADLVVGKVCDDSGYCPEDAIIAGMEWAAAGDAVAVNLSLGIGPTDGTDPMSVAVDTLTEDTGTLFVAAAGNDGWDMTVSSPAAADAALAVGSVTKSDELSDFSSRGPRVGDWAVKPEIAAPGSGIVSARAAGTAMGSLVDEHHTSADGTSMASPHVAGAVALLAEANPEWRAREFRAALMAAAEPLAGVPVSGQGAGRLDVARAMRQSVVAEPSSLSLGNFTWPRDGEEPAAGTVTYRNTGEEDLILDLAVDLVTEDGEAVPADLVELSVSDLLVPAGGAAGATVTVDVAHGTTGYLSGTLRATAEGGVAVSTPVGLHLEPESYDLGVDVLDRDGRSTSRAALLVEDADTGYSYYLEADGNGDYAVRLPGGTYNLLARIGDDTSDEYTYVVERAVQLTSDARVTVDATPAVPIEVRTERPSELRYHDSALLSEDRQSSLGALGFGTKQKYAVPARGSFALNYKPTLVSSSEDEYRYHLATQFVDEIPAEPVLAPRDEELAEVTSRYQAQGVAAAGLRTVVGQLVDDWSLFGFGLPVDVPGSGTDYHSVTDDVEWREYLGFQDDLGENYEETGRVSVYAAGAASIRWNTAPVTILGEGRRTGDDLTFSPRYFVTSDTDQYYGYGSADVFAGELTLSDEQGVLASSDEYGFLRAPVPSEPGMYTLEATATRNVEWSMLGTSARARWTFRSENPGTEGPTGLPLMGVRFTSVATVDDPLGVLPGNGEHAFAVTVEDTAGGIAELAVEYSVDDGETWEPLEVVDGVVSVVHPAEGFVSLRARAADSEGNSVEQAVIRSYQVGPSTR
>CP025990.1|AUS79539.1|3620352_3620574_-|DUF3618-domain-containing-protein
MARDPDEIEREIEDARTALAGTLDELGSKANPQRFIESGKASARERLADPRVKYSLMAIGALIAFALLRRLFR
>CP025990.1|AUS79540.1|3622312_3623212_-|alpha/beta-hydrolase
MVEERHVEGSPRLVVRDHGGQRTGRDIVVLHGFGGNALNWEAFVPLLTSRHRVVACDLRCHGRSGDGAWDWEALVDDVDRVVADLGAERPVVVGHSLGGAVATLWAGHHPEAAGAVNIDGFRGVETEERHYLGIDPDELAARLAELSADFAAQAAALAEPLQPEAVEVARAQHRTAGGDRAVEAFDRGLAVRDGLTVARPDPGTVAAFRTWMAALDLTEPLAAARCPVLVLTATRDLPEADRYADLLAAWRRGVERDLDSVARTNPRVRVEHVAASHAMVLESPDIIAGHVLDFLDILG
>CP025990.1|AUS79541.1|3623362_3623860_+|hypothetical-protein
MTLENALRDQLVALVDARCVDPLEILLEDADTADALRHRVRERAPAWARAMVAGDDAEAILAITRVIATLYPGDGPFDPPADWWRTPLGTITARRVGHPSAHALSYPVAGAMLGISRQGVHDLVNRGKLERHPDGGVTASSVRDRSRANALPQAPHHPGSGADRS
>CP025990.1|AUS79542.1|3623938_3624904_-|amidohydrolase
MSGGRIDLHAHYLPDFYREALAESGHGRRAAISSLPEWDEQLALRTMDRLGVRTAMLSVSTPGVHFGDADRAVDLARRVNEEGARLVREHPGRFGFFASLPLPEVEPAVAELRHAFDVLGADGVILQSNHHGLYLGDERLEPVYAEVAARGSVVFVHPAMPFVAEHLALGYPQPALEFPFDTTRSVVDLVLSGVLERHPDLRVVVSHAGAVLPVLANRVDLLVPMLAVPKGRSTPSLRAAMRRLHFDLAGAPVPELLGALLSLADPDRLHYGSDYPFFPAALGRELADRLAETPLLDGELRRAVFEDNAVRLFPRLASPTS
>CP025990.1|AUS79543.1|3625225_3625957_-|chitinase
MSITRLVKAVATVAAVSALLVSAPMTTSTATAEPAAPQGFVVSEAQFNQMFPNRNPFYTYQGLTAALSSYPGFTNTGDETTRRREAAAFLANASHETGGLVHIVEQNEANYPHYCDWSQPYGCPAGQAAYYGRGPIQLSWNFNYKAAGDALGLDLLGNPWLVQNDASVAWRTALWYWNTQSGPGTMTPHHAIVNGHGFGETIRSINGALECDGANPGQVQSRVDTYQRFTQILGTTPGGNLYC

Crispr_ID: CP025990_28

• CRISPR_ID: CP025990_28
• CRISPR_location: 4214408-4214679
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP025990_28

Consensus_repeat	Method
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	CRISPRCasFinder
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	CRT
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	PILER-CR

spacers of CP025990_28

>28.1|4214437|31|CP025990|CRISPRCasFinder,CRT
GCCATCGGCTCGAGGCCGAGCGTGTCGGCTA
>28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR
GTGACCTGGCCGTTGCCGACGAACGCGTTCAC
>28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR
CGGTGCGGGTTGGCGGTCTATCGGTGCGGCTA
>28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR
TGCGCCGGGTCGGGGACCACGTCCACGTCGCC

CRISPR arrays and Neighbor proteins around CP025990_28

CRISPR arrays

The CRISPR arrays of CP025990_28

>merge|CP025990|28|4214408-4214679|CRISPRCasFinder,CRT,PILER-CR
CCGCTCACCCTCGCTTGCGCGGGGCTTACGCCATCGGCTCGAGGCCGAGCGTGTCGGCTACGGCTCACCCCCGCTTGCGCGGGGCTTACGTGACCTGGCCGTTGCCGACGAACGCGTTCACCGGCTCACCCCCGCTTGCGCGGGGCTTACCGGTGCGGGTTGGCGGTCTATCGGTGCGGCTACGGCTCACCCCCGCTTGCGCGGGGCTTACTGCGCCGGGTCGGGGACCACGTCCACGTCGCCCGGCTCACCCCCGCTTGCGCGGGGCTTAC

>CP025990|28|27|4214408-4214679|CRISPRCasFinder
CCGCTCACCCTCGCTTGCGCGGGGCTTAC	GCCATCGGCTCGAGGCCGAGCGTGTCGGCTA
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	GTGACCTGGCCGTTGCCGACGAACGCGTTCAC
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	CGGTGCGGGTTGGCGGTCTATCGGTGCGGCTA
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	TGCGCCGGGTCGGGGACCACGTCCACGTCGCC
CGGCTCACCCCCGCTTGCGCGGGGCTTAC

>CP025990|28|21|4214408-4214679|CRT
CCGCTCACCCTCGCTTGCGCGGGGCTTAC	GCCATCGGCTCGAGGCCGAGCGTGTCGGCTA
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	GTGACCTGGCCGTTGCCGACGAACGCGTTCAC
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	CGGTGCGGGTTGGCGGTCTATCGGTGCGGCTA
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	TGCGCCGGGTCGGGGACCACGTCCACGTCGCC
CGGCTCACCCCCGCTTGCGCGGGGCTTAC

>CP025990|28|21|4214468-4214679|PILER-CR
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	GTGACCTGGCCGTTGCCGACGAACGCGTTCAC
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	CGGTGCGGGTTGGCGGTCTATCGGTGCGGCTA
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	TGCGCCGGGTCGGGGACCACGTCCACGTCGCC
CGGCTCACCCCCGCTTGCGCGGGGCTTAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS79887.1|4218985_4219303_+|thiamine-binding-protein	unknown	unknown	gnl|CDD|376658
CP025990.1|AUS81833.1|4206488_4206845_+|hypothetical-protein	unknown	unknown	gnl|CDD|367653
CP025990.1|AUS81834.1|4221270_4222218_+|co-chaperone-YbbN	unknown	unknown	gnl|CDD|225660
CP025990.1|AUS79879.1|4210516_4210969_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
CP025990.1|AUS79877.1|4207008_4207635_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS79890.1|4224854_4225490_+|NADP-oxidoreductase	unknown	unknown	gnl|CDD|224996
CP025990.1|AUS81832.1|4202486_4202684_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS79876.1|4203600_4204371_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|131480
CP025990.1|AUS79888.1|4219413_4221153_+|methylmalonyl-CoA-mutase	unknown	unknown	gnl|CDD|239652
CP025990.1|AUS79881.1|4212107_4213313_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|180261
CP025990.1|AUS79884.1|4216588_4217584_-|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
CP025990.1|AUS79880.1|4210927_4211869_+|fimbrial-assembly-protein-FimA	unknown	unknown	gnl|CDD|377639
CP025990.1|AUS79885.1|4217992_4218337_+|DUF3817-domain-containing-protein	unknown	unknown	gnl|CDD|378962
CP025990.1|AUS79875.1|4202765_4203515_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|225496
CP025990.1|AUS79883.1|4214862_4216398_-|DNA-polymerase-IV	unknown	unknown	gnl|CDD|235118
CP025990.1|AUS79878.1|4207886_4210289_+|penicillin-acylase-family-protein	unknown	unknown	gnl|CDD|376618
CP025990.1|AUS79886.1|4218343_4218865_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
CP025990.1|AUS79882.1|4213309_4214278_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
CP025990.1|AUS79889.1|4222255_4222621_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81835.1|4222621_4223938_-|hypothetical-protein	unknown	unknown	gnl|CDD|225203

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS79887.1|4218985_4219303_+|thiamine-binding-protein	gnl|CDD|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	2.63259e-30
CP025990.1|AUS81833.1|4206488_4206845_+|hypothetical-protein	gnl|CDD|367653	pfam03779, SPW, SPW repeat. A short repeat found in a small family of membrane-bound proteins. This repeat contains a conserved SPW motif in the first of two transmembrane helices.	0.000115005
CP025990.1|AUS81834.1|4221270_4222218_+|co-chaperone-YbbN	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	7.38586e-72
CP025990.1|AUS79879.1|4210516_4210969_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	1.42971e-49
CP025990.1|AUS79877.1|4207008_4207635_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.69321e-11
CP025990.1|AUS79890.1|4224854_4225490_+|NADP-oxidoreductase	gnl|CDD|224996	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only].	5.8865e-28
CP025990.1|AUS79876.1|4203600_4204371_+|alpha/beta-hydrolase	gnl|CDD|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	2.05135e-34
CP025990.1|AUS79888.1|4219413_4221153_+|methylmalonyl-CoA-mutase	gnl|CDD|239652	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM from S. cinnamonensis is comprised of a large and a small subunit. The holoenzyme appears to be an alpha2beta2 heterotetramer with up to 2 molecules of coenzyme B12 bound. The small subunit binds coenzyme B12. ICM catalyzes the reversible rearrangement of n-butyryl-CoA to isobutyryl-CoA, intermediates in fatty acid and valine catabolism, which in S. cinnamonensis can be converted to methylmalonyl-CoA and used in polyketide synthesis.	0
CP025990.1|AUS79881.1|4212107_4213313_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
CP025990.1|AUS79884.1|4216588_4217584_-|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.97089e-96
CP025990.1|AUS79880.1|4210927_4211869_+|fimbrial-assembly-protein-FimA	gnl|CDD|377639	pfam06267, DUF1028, Family of unknown function (DUF1028). Family of bacterial and archaeal proteins with unknown function. Some members are associated with a C-terminal peptidoglycan binding domain. So perhaps this could be an enzyme involved in peptidoglycan metabolism.	2.84087e-51
CP025990.1|AUS79885.1|4217992_4218337_+|DUF3817-domain-containing-protein	gnl|CDD|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	1.58776e-22
CP025990.1|AUS79875.1|4202765_4203515_+|alpha/beta-hydrolase	gnl|CDD|225496	COG2945, COG2945, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	2.47004e-15
CP025990.1|AUS79883.1|4214862_4216398_-|DNA-polymerase-IV	gnl|CDD|235118	PRK03348, PRK03348, DNA polymerase IV; Provisional.	0
CP025990.1|AUS79878.1|4207886_4210289_+|penicillin-acylase-family-protein	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	0
CP025990.1|AUS79886.1|4218343_4218865_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.45064e-18
CP025990.1|AUS79882.1|4213309_4214278_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	4.29542e-123
CP025990.1|AUS81835.1|4222621_4223938_-|hypothetical-protein	gnl|CDD|225203	COG2321, COG2321, Predicted metalloprotease [General function prediction only].	6.87411e-21

Protein sequences

>CP025990.1|AUS79882.1|4213309_4214278_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MSHAEVDDLVQRARAGQPRALGRLISLVEDASPRLRDVAAELTPHTGHARVIGLTGPPGVGKSTSTSALVTALRAQGRTVGVLAVDPSSPFSGGALLGDRVRMQDHALDPGVFIRSMATRGHLGGLAWATPQALRVLDAAGFDVILVETVGVGQSEVDVISLADTTLVLLAPGMGDGIQAAKAGILEVADVFVVNKADREGTDQTVRELKHMISLGRREKEGPSWRPPIVRTVASRAEGMTELVAAVDEHHDWMREHGELSARRRRRAASEVEAIAVEELRGRLGDVRGGSALVDLADRVLAGRTDPYTAADELVAGLRPRR
>CP025990.1|AUS79881.1|4212107_4213313_+|acetyl-CoA-C-acetyltransferase
MTGSVIVAGARTPIGRLLGSLKDQSAAQLGGVAIRAALDRSGVTPDQVQYVIMGQVLTAGAGQIPARQAAVAAGIPMDVPALTINKVCLSGLDAIALADQLIRAGEFDVVVAGGQESMSQAPHLLPNSRTGTKYGDAVLRDHMAHDGLFCAFDQVAMGESTERYNSRYGLARAEQDAFAAASHQRAAAATAAGVLAEEIVPVELPGRRGAPGVVVDRDEGIRPDTTAEGLAALRPAFATDGTITAGSASQISDGAAAVVVMSRARAEELGLEWIAEIGPHGVVAGPDASLHEQPSRAIAAACRRAGVTPADLDLVEINEAFAAVGLVSARELGVDLDRVNVNGGAIALGHPIGMSGARLVLHLALELRRRGGGLGAAGLCGGGGQGDALLLRVPEADRAER
>CP025990.1|AUS79880.1|4210927_4211869_+|fimbrial-assembly-protein-FimA
MVDGGDELAEFLRHSRRVCGADLDYGASVTFSIVARDPVTGELGAAVASGVLAIGARALAVEPGLAAVVVQGAAGADQLHAVLDRLREGNEPEEAVRAAGLSAEMQCGVVTPSESTSWTGDACPGAAGGVALPEVAVQGNLLTSTEVWEAARETFHTTTGPLHRRLVASLRAGQQAGGDARGQQSVALVVRAAGGTEPLPLDLRVDDHRDPLRELGRLLDVHHAHDLIASGSSVLHEDIDMARRLVDASARLPGDALLAGWAAVGALVHGLPEAALLVNAARSQTPRFAALCALRASHGGPLAPAWNKLAELG
>CP025990.1|AUS79879.1|4210516_4210969_-|methylmalonyl-CoA-epimerase
MPEELSQFVTAIDHVGVAVADLEEAIAFYRDTFGLRVVHIESNEEQGTREAMLRAAGDAGDGAALQLLAPLSADSPIASFLDRRGPGLQQLAYRVWDIDAISTALRHKGVRLLYEEARRGTGGSRINFVHPKAAGGVLIELVEPPKSALP
>CP025990.1|AUS79878.1|4207886_4210289_+|penicillin-acylase-family-protein
MRIPSTGRDPAARWRRRTTAVALVALLPVTASGAADGEEGAGTTVTLPGLSEEVEILVDEWGIPHIFAANTDDLYLAQGFNAARDRLFQIDLWRKRGLGELSSDLGPDYVEQDRAARLFLYDGDMEAEWASYGPDAERTVTAFVTGINAYVDWLEENPDQLPPEFAELGYEPSRWAPEDVVRIRSHGLTRNLTSEVARARVACAEGTDADLVRRGLEPDWTTEVPDGLDPCAIGDEVLDTFRLATSGVAFSDGEVRVLEAEDPTVVGSNNWVVAPERTSTGRPILANDPHRAYSAPALRYVTHLSAPGLDVIGAGEPALPGVSIGHNGTAAFGLTIFSIDQEDLYVYELDPADHDRYRYGDGWERVEVEEQRIEVAGEDAVTVETRHTRHGPLIHVDEDRDLGYAVRTAWSEPGMSPYLGSLAYQGARSFDEFEEAMRTWGAPTENQVYADVSGEIGWVPGGLAPERSGYDGLLPVPGDGRYEWTGFHDGAELPRSRNPAEGYVATANEMNLPPDFPHEEYGLGYEWTNPFRFQRITEVLAQDTDHGLADSAALQLDQLSLPARRITALLPGLEPGDAITSRARDLLVGWDHVETADSGPAALFEVWLSRHLGPEFVRLAAPEAAEIIEQPDTLVLVEELENPGRWLDQEERDELLLTTLRAAYRETGELLGGNDRRWEWGRLQHTLFAHPVGRGGAEDDPASLDVGPFPRGGSKDTVNQSSYRVSDFRQTNGPSFRMVLDVGEWDRSLVINGPGQSGDPDSPHYRDHAEPWRDGEFVPLLYSRAEIERHVGERIVLLPG
>CP025990.1|AUS79877.1|4207008_4207635_+|TetR/AcrR-family-transcriptional-regulator
MRRTGQRDGVGARERILTAAGELFAESGFDATPTSRIAERAEVPKGLVHYYFRRKQDLLAALIERLPDVRVDLTSVVVPGDVATSLRQLVAALDRGLDASPLLSHLLWRETDTHPAVRDALDARLRGIVSQIREVLIAAREATGGPAAETALVGEGRVGAREGSDDIESAAALLALAVSYRHSVARHTQPADVLDRELDFVARALESG
>CP025990.1|AUS81833.1|4206488_4206845_+|hypothetical-protein
MTGKWSRWQDWAAFALGVYTVISTIWLDVTAGTAWTMIVLGALLAISGLWSLSAPGSVASEWTHMLFGVLLFLAPWVIGYTDQGGAAWTSWIVGVLAVLVSAAALPEANTAHRGVMAH
>CP025990.1|AUS79876.1|4203600_4204371_+|alpha/beta-hydrolase
MTPPLVLLHAFPVDARMWGGVRPLLGPGRRVFAPDQRGLGGRPLTRDGDVPQPDLDVVADDVLAELDAQGVRRVVVGGCSMGGYVAMALLRRAPGRVAGLVLVGTRAGADGPEQRANRLRVADRLEREGATGWSAESAVEGLLGPTTRASRPEVVRAVRGWAREQSPAGVAWAQRAMASRRDSRALLAAATVPVLVVAGQEDGVVPVGEHRALAGDIAGSALRVVPGAGHLAPVEDPVGFAGCLVPWLDEVASAGE
>CP025990.1|AUS79875.1|4202765_4203515_+|alpha/beta-hydrolase
MSTQIRAGTVLPARREPLTLHTADDLRLVGELAMPERRAPVATLVCLHPLPTHGGMMDSHVYRKAAWRLPALADIAVLRFNTRGTESAAGRSEGEFSHGDAERHDVVAALEYAEFEDLPNVWLLGWSFGTDLALMHGCDPLVRGAILLSPPLRYSREEHLRVWAESGKPVHALVPEFDDYLRPPAAHERFQAIPGARVVPFEGAKHLWVGRADDVLDEIVSIVAPDVPTPLPRSWDGPYETHQFTVHQS
>CP025990.1|AUS81832.1|4202486_4202684_+|hypothetical-protein
MVRTVPGSQAVKTYRCPGCDHEIRAGIPHVVAWPADEYGSAEERRHWHNGCWQARGRRGPTRRWW
>CP025990.1|AUS79883.1|4214862_4216398_-|DNA-polymerase-IV
MVTASGSGRWVAHLDMDAFFSSVEQLTRPTLRESPVLVGGAGPRGTVAGASYEARAYGARSAMSMAHARRLCPVATVIPPRFTVYQAVSARVFDLVRRFSPVAEQVSLDEAFIEPGSLAGAQADEVRRVLAELRARIHSEVGMVASIGAGSGKSVAKIASDLAKPDGLLVVTPEEQRAVLRDLPVRALWGIGPVSEGKLRRIGVQTLGEFADLDPATVTALLGTAVGRELHDLAHGRDPRPVAERAEVKQVSAETTFDTDLVDGGALESAAVSMTSAAHQRLVRSHRAARTVTVKVRSADFATVSRSETVRAATSDLSSLSAMARRLVSSAVPPGTPVRLVGVSLAGLTTAEQESLFPAPPTAGPEPHPDEETGPDEATDAGPTPRPDTAPLPGGRDRGGRGWAAGDDVRHPEHGHGWVQGAGVGRVTVRFETRTTGPGPARTFAMDDPALRVADPLASLDWLPVVGRRNDLARARTVEDGRTPHPGPAAGSTTVMEWVAPVGQEHDAVSS
>CP025990.1|AUS79884.1|4216588_4217584_-|LacI-family-transcriptional-regulator
MNDVARLADVSIKTVSRVVNNEPGVHPSTAEIVLSAIDQLGFRRNLGARNLRRGSATGTLGLLLEDVANPFYSQVTRAVEEVARKHDHQVLAGSSDESHVRERELALEFCSRRVDGMLLVPSGVQHGYLVPEMRAGTPIVFLDRPPGDIAADTVLVDNQGGVAEAVAHLVRHGHRRIAFFGDSPHIYTAGERVRGYREGHASAGLPFDERLVFMGPHDETTLTCGLSRISGGAARATAVIAGNNRITVGLLRALRGRSHRPALVGFDDFELADLMAPPITVISQDVPELGRTGAELLFSRMAGDGSPPQRVVLPVRLIPRGSGETPPPPED
>CP025990.1|AUS79885.1|4217992_4218337_+|DUF3817-domain-containing-protein
MFTTPVGRFRLAALAEAASWVGLLVGMFFKYVVVHNDVGVAIFGRVHAVLFILYVVVALVTARALRWNLVTLFWALVASVPPLGTVLFERWATRKGKLADPGAVRAPLDERAAA
>CP025990.1|AUS79886.1|4218343_4218865_-|MarR-family-transcriptional-regulator
MTAQQPLPFDPIARAAELWASRIGPSSTMAAVTSVMRVQQLLQSAVDGALRPLSLTFARYEALVLLTFSRRGALPMRVMGERLQLHPTSVTNIVDRLERDKLVRRTPHPTDRRTTLVEITDAGRGRMEAATTAVTSVNFGMRGLNEQEMTQLTQLLTGVRLAHGDFSREPTEG
>CP025990.1|AUS79887.1|4218985_4219303_+|thiamine-binding-protein
MLVAFSVSPTGGARGEESPESVSGAVSEAVRIVRDSGLPYELSSMYTTVEGEWDEVMDVVRRATDAVLARAPRASLVIKADIRPGFTGQLRAKVERVERRLAGEG
>CP025990.1|AUS79888.1|4219413_4221153_+|methylmalonyl-CoA-mutase
MSERGTGRDPRPDDPEPGRRRWRERYEAAAASGRVPDVDVTTLSGVPVHPVYGPPEGGVVPGFDRIGWPGEFPFTRGPHTTGYREKPWTIRQFAGFGTARQTNERYRTILAQGGGGLSVAFDMPTLMGRDSDDERARGEVGHCGVAVDSAADTDLLFEGIPLDQVTTSMTISGPAVPVFCMYLVSAERQGVDVGALNGTLQTDIFKEYIAQKEWLFGPEPHLRLIGDLLEYCVRNTPDYKPLSISGYHIREAGATAAQELAFTLADGFGYVELGLARGLDVDRFAPGLSFFFDAHIDFFEEIAKFRAARRTWARWLRDVYGATTEKAQRMRFHTQTAGVSLTAQQPDNNIVRTAVEAMAAVLGGTNSLHTNALDEVLALPGERAARIALRTQQVIAEETGITNVADPLGGSWYVEALTDRLEEEAERIFGRIRDMAASAVPSGEHPIGEMTSGILRGIEDGWFAGEIADAAFAHQRALERGDRRLVGVNRHVEPTEGDLEILRVSDEVEREQQRVLAARKTARRQRVVAEALAELVRAARGEDNLIEPMLAAVRAEATLGEICGALRAEWGDYTEPARF
>CP025990.1|AUS81834.1|4221270_4222218_+|co-chaperone-YbbN
MSGAVDLSAVKARADAARQQTQTPASPAGGPGAGNGTPGTSSPHVIDVTEADFQTAVLERSLQVPVVVDLWATWCGPCKQLSPVLEKLAAAANGAWVLAKVDVDANPRIAQVFGVQSVPTVVAIAGGQPVDAFAGAQPEPQIREWIGSLLDALRDKLPGISAAEQGATPAEEPTEPEVPEDPRFTEAEAALDRGDFDAAERAYQHILDTEPANEQARDALNQVRFLARAQAADPSSVERAAAAPDDVDAQLAAADYELSAQQEVAAFDRLIELVRRTSGEDRDRVRTHLVELFELFPASDERVVAARRALASALF
>CP025990.1|AUS79889.1|4222255_4222621_+|hypothetical-protein
MNHHTPAGRRAAVDAGRRWTPGGGGGGGDRRAQRRPAAPVAGVREDALRTRSAACRTPTPPLPGRARRGPSRPGAAADPGPPSRFAGGGEEEVGTRADVPVRGVGADDHGLDPSVTPGAGA
>CP025990.1|AUS81835.1|4222621_4223938_-|hypothetical-protein
MSPDEAAGLPITSGPSGPRASTPPIRATALNSDGGPLDQLALAAVTDLYDYWEVEFPATFPGLTFEPVATLLSYDANGQGVLVCGMDTTGVPNAFYCPSDDSIAWDRGVLLPELRNTFSEMAVVTVIAHEMGHAVQYKAGQMGPAMPTILAEQQADCYAGAYFRYVADGESPFFEISTGEGLNAILATLFFIRDQAGTDYLAPRAHGSAFDRVSAFTFGFTDGPSRCAEMDIEELEGRITQLEFAEGDANSGELPIVEENVEHVAGSLREVFARFGDGPALDYQGVSCGNTAPVAFCEAEDVISLDLAALQVIGTAPRRQGDSGIGDFAAFAEIASRYALWVQARQGLPLRGDEAGLRTACLVGAWAGELLPDGAPRPGRVRISPGDLDEAIAELLTEGSLIAADIDGESIPAGFARVESLRIGFEDGMDTCLDEFSG
>CP025990.1|AUS79890.1|4224854_4225490_+|NADP-oxidoreductase
MDVAIIGAGEMARGLAGRLAPAAHSVTVYGRTTRAAERLVTAVARDDHAVRPATLGDPVTADLLVLAVPFAAAPAIIAQYGEHLPGRVLVDVSNPDRGLPGAGASPEPGPASAAEELARLVPAGTVVVKAFNTVTAGALLGPGVVDVFVATDDEQARVDLFTLVRAAGMLPLNAGGLRGARELEGMGRLHLVVRRALGTAAHSSFALRMVG

Crispr_ID: CP025990_29

• CRISPR_ID: CP025990_29
• CRISPR_location: 4677437-4677657
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP025990_29

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGACGACACGTTCGG	PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRT

spacers of CP025990_29

>29.1|4677473|32|CP025990|PILER-CR
TCGACAACCGGGGGACACTGTTCCTCCCGGGC
>29.2|4677541|25|CP025990|PILER-CR
CAACATCCCGAAGTCGAAGGAGTCA
>29.3|4677473|35|CP025990|CRISPRCasFinder,CRT
TCGACAACCGGGGGACACTGTTCCTCCCGGGCCGT
>29.4|4677536|33|CP025990|CRISPRCasFinder,CRT
CAACATCCCGAAGTCGAAGGAGTCACCGAACAC
>29.5|4677597|33|CP025990|CRISPRCasFinder,CRT
GGCCTCCTGCTTCAAGTTCGTGAAGTCGTTGGC

CRISPR arrays and Neighbor proteins around CP025990_29

CRISPR arrays

The CRISPR arrays of CP025990_29

>merge|CP025990|29|4677437-4677657|PILER-CR,CRISPRCasFinder,CRT
CGGAAAGTGTCGTCCCCGCGCACGCGGGGCTGTTCCTCGACAACCGGGGGACACTGTTCCTCCCGGGCCGTGTCGTCCCCGCGCACGCGGGGCTGTTCCCAACATCCCGAAGTCGAAGGAGTCACCGAACACGTCGTCCCCGCGCACGCGGGGCTGTTCCGGCCTCCTGCTTCAAGTTCGTGAAGTCGTTGGCGTCGTCCCCGCACGCTGGGGGTGGTGCG

>CP025990|29|22|4677437-4677596|PILER-CR
CGGAAAGTGTCGTCCCCGCGCACGCGGGGCTGTTCC	TCGACAACCGGGGGACACTGTTCCTCCCGGGC
CGTGTCGTCCCCGCGCACGCGGGGCTGTTCCCAACA	TCCCGAAGTCGAAGGAGTCACCGAA
CACGTCGTCCCCGCGCACGCGGGGCTGTTCC

>CP025990|29|28|4677445-4677657|CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TCGACAACCGGGGGACACTGTTCCTCCCGGGCCGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CAACATCCCGAAGTCGAAGGAGTCACCGAACAC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGCCTCCTGCTTCAAGTTCGTGAAGTCGTTGGC
GTCGTCCCCGCACGCTGGGGGTGGTGCG

>CP025990|29|22|4677445-4677657|CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TCGACAACCGGGGGACACTGTTCCTCCCGGGCCGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CAACATCCCGAAGTCGAAGGAGTCACCGAACAC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGCCTCCTGCTTCAAGTTCGTGAAGTCGTTGGC
GTCGTCCCCGCACGCTGGGGGTGGTGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80219.1|4688465_4691858_-|hypothetical-protein	unknown	unknown	gnl|CDD|378342
CP025990.1|AUS80224.1|4696172_4696700_+|damage-inducible-protein	unknown	unknown	gnl|CDD|234789
CP025990.1|AUS81892.1|4671403_4672348_+|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl|CDD|235107
CP025990.1|AUS80217.1|4681531_4683178_+|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl|CDD|224006
CP025990.1|AUS80214.1|4670109_4670862_+|thymidylate-synthase-(FAD)	unknown	unknown	gnl|CDD|234847
CP025990.1|AUS80218.1|4683337_4684444_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224983
CP025990.1|AUS81890.1|4666096_4666702_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
CP025990.1|AUS80223.1|4695495_4696176_+|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|273139
CP025990.1|AUS81893.1|4678908_4681248_+|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
CP025990.1|AUS80216.1|4677726_4678494_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
CP025990.1|AUS80213.1|4669284_4669866_-|toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|310261
CP025990.1|AUS80210.1|4665640_4666090_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80222.1|4694053_4695499_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl|CDD|273453
CP025990.1|AUS80215.1|4674232_4677109_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
CP025990.1|AUS80221.1|4693360_4693942_-|amino-acid-N-acetyltransferase	unknown	unknown	gnl|CDD|236132
CP025990.1|AUS80212.1|4668271_4669186_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80209.1|4664870_4665644_+|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl|CDD|234595
CP025990.1|AUS80211.1|4666993_4668229_+|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|225755
CP025990.1|AUS81891.1|4672449_4674084_+|ribonuclease-J	unknown	unknown	gnl|CDD|223668
CP025990.1|AUS80220.1|4692110_4692641_-|hypothetical-protein	unknown	unknown	gnl|CDD|370266

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81892.1|4671403_4672348_+|4-hydroxy-tetrahydrodipicolinate-synthase	gnl|CDD|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	1.77571e-135
CP025990.1|AUS80214.1|4670109_4670862_+|thymidylate-synthase-(FAD)	gnl|CDD|234847	PRK00847, thyX, FAD-dependent thymidylate synthase; Reviewed.	3.01628e-95
CP025990.1|AUS80217.1|4681531_4683178_+|phosphoenolpyruvate--protein-phosphotransferase	gnl|CDD|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	8.27783e-162
CP025990.1|AUS80218.1|4683337_4684444_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	7.93178e-35
CP025990.1|AUS81890.1|4666096_4666702_-|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.79989e-05
CP025990.1|AUS80223.1|4695495_4696176_+|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	5.02619e-33
CP025990.1|AUS81893.1|4678908_4681248_+|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.54983e-153
CP025990.1|AUS80216.1|4677726_4678494_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	5.14211e-33
CP025990.1|AUS80213.1|4669284_4669866_-|toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|310261	pfam05534, HicB, HicB family. This family consists of several bacterial HicB related proteins. The function of HicB is unknown although it is thought to be involved in pilus formation. It has been speculated that HicB performs a function antagonistic to that of pili and yet is necessary for invasion of certain niches.	0.000217301
CP025990.1|AUS80219.1|4688465_4691858_-|hypothetical-protein	gnl|CDD|378342	pfam09992, NAGPA, Phosphodiester glycosidase. This is a family conserved from bacteria to humans. The structure of a member from Bacteroides has been crystallized and modelled onto the luminal region of the human member of the family, the transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. There is some conservation of potentially functional residues, implying that in the bacterial members this family acts in some way as a phosphodiester glycosidase. The human protein is also present, so the eukaryotic members are likely to be catalyzing the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides.	3.67004e-29
CP025990.1|AUS80222.1|4694053_4695499_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl|CDD|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	3.54648e-127
CP025990.1|AUS80215.1|4674232_4677109_+|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	3.50967e-73
CP025990.1|AUS80221.1|4693360_4693942_-|amino-acid-N-acetyltransferase	gnl|CDD|236132	PRK07922, PRK07922, amino-acid N-acetyltransferase.	3.6448e-100
CP025990.1|AUS80224.1|4696172_4696700_+|damage-inducible-protein	gnl|CDD|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	3.07724e-49
CP025990.1|AUS80209.1|4664870_4665644_+|4-hydroxy-tetrahydrodipicolinate-reductase	gnl|CDD|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	1.41415e-97
CP025990.1|AUS80211.1|4666993_4668229_+|winged-helix-turn-helix-domain-containing-protein	gnl|CDD|225755	COG3214, COG3214, Uncharacterized protein conserved in bacteria [Function unknown].	2.98002e-109
CP025990.1|AUS81891.1|4672449_4674084_+|ribonuclease-J	gnl|CDD|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
CP025990.1|AUS80220.1|4692110_4692641_-|hypothetical-protein	gnl|CDD|370266	pfam09056, Phospholip_A2_3, Prokaryotic phospholipase A2. The prokaryotic phospholipase A2 domain is predominantly found in bacterial and fungal phospholipases, as well as various hypothetical and putative proteins. It enables the liberation of fatty acids and lysophospholipid by hydrolysing the 2-ester bond of 1,2-diacyl-3-sn-phosphoglycerides. The domain adopts an alpha-helical secondary structure, consisting of five alpha-helices and two helical segments.	5.80055e-54

Protein sequences

>CP025990.1|AUS80215.1|4674232_4677109_+|FAD-binding-oxidoreductase
MITIAGRHAHGEAVVTVGLAEELRARVAGEVLADSATRAVYSSDASNYRHVPRAVVLPRDAEDVAATLAVCAEQGVPITHRGGGTSIGGQACGPGVVLDHSRHLNRLLEFDPDRGTARVEPGLVLDDLRDATLPHGLTFGPNPSSHSRCTIGGMIGNNACGSSAVAWGTTADNVVDLDVLLADGTRLTVSDLDSAGPLTRPLRALVDRRRAALRTGLPTLPRRVSGYALDALLPENGEDLARALVGSEGTCVTLLGATVRLIRPPAVRVLAVLGFPDAFAAADAVPAILPHGPLTVESVDRALVEAHRAVHGPSAATESLPDGNAWLYCETGGDTRAEAVLRAEGLARDLDVPAVVLAESAHQRALWRIREEGSGIATRMSDGTEGYPGWEDAAVPPERLGDYLRDFEALLGQHGRRGIYYGHFGEGCIHVRLDFDLISSTGVRGFREFMLDAADLVAGYGGSLSGEHGDGQARGELLTRMYPAEVIDAFGEFKAVFDPDRLLNPGQIVDPLPLDANLRWPSEDTVTVPVDTMFSYPHDGGSFVAAARRCVGVGKCRNTGGGVMCPSYRATRDERHSTRGRARALVEMLHGEVIRDGWRAEEVHEVLDLCLSCRACRSECPVEVDMATYKAEFLHQHYRNRIRPAAHYSMGWLPALAVLAQPFARPLNAALSARPVASAVRRLGGVDPHRDLPVFAPETLTRWFRRRAPRPPAAGGRRVLLWPDTFTNTFSPGVGRAAVEVLEAAGYTVELPRERVCCGLTWVSTGQLGIARRVMRRTARVLAPYVQAGVPVVGLEPSCTAALRTDLGELLPGTGWLGEGVRTFAELLVADDLDWLPRGAERAAVAQTHCHQSAVLSTDPDRTLLDHVGVRADFVDGCCGLAGNFGFEKGHHEVSMACAEDSLFPAVRAAESDTLVLADGFSCRTQLAQGLGRDSSHLAEVLRDALRAAATRGGTPAS
>CP025990.1|AUS81891.1|4672449_4674084_+|ribonuclease-J
MRVVALGGIGEVGRNMTVFEYDGRLLVVDCGVLFPEDDAPGVDLILPDFRAIEDRIDDIEALVLTHGHEDHIGAVPFLLRLRPDLPVVGSRFTLALLAAKCKEHRQTPHMREVREGERTRHGAFDCEFFAVNHSIPDALAVALRTPAGTVLHTGDIKLDQVPLDGRLTDLGGFSRLGDEGVDLFLVDSTNAEVPGFVPLERDIGPVLDGVIGKATQRVIVACFASHVHRVQQVLDVAVAHGRRIALVGRSMVRNMGVAADLGLLQVPDGLLVDLDAAMRLPEDQVLFVSTGSQGEPLSALSRMARGEHRQISIKPGDTVVLASSLIPGNETAVFGVVNGLTRLGANVVHQANAKVHVSGHASAGELLYLYNAVRPTNVMPVHGEWRHLRANAELAELTGVPADRVVLAENGVVVDLVDGLAGRTGRVEVGQVYVDGLSVGDVGESTLSDRLILGEGGFIAITVAVEAATGRAVAPPTVSGRGFSDDPKALDEVVSLVENELSRTEAEGINDTHRIAQAVRRVVGRWVAATYRRRPMIVPTVLPV
>CP025990.1|AUS81892.1|4671403_4672348_+|4-hydroxy-tetrahydrodipicolinate-synthase
MTGCPTASPGRPFGRVLTAMVTPFDADGALDLDLAQELAVHLIDNQGNDGLVVNGTTGESPTTTDKEKAELIRAVVAAVGDRATIVAGAGTNDTAHSTQLARDAEKSGAHGLLVVTPYYSRPPQDGLVSHFTAVADATELPVMLYDIPPRSVVPIEVDTLRTLAEHPRILAVKDSKHNMWAGSEVMATTDLAYYSGEDPLNLPWLAVGAVGYVSVIGHVVADRLRVMLDAFEGGDLAKAREVHHGLLPVYRSMNQLGGVIFSKTALRLCGYETGQPRLPLPPASEEDVRLITADLWEAGLVLVNPDTVAGVASQ
>CP025990.1|AUS80214.1|4670109_4670862_+|thymidylate-synthase-(FAD)
MTELVSPKVQLIAKTEFTPPADVPWETDAEGGEALAEFAGRACYQSWRKPNPATATNAGYLRHILEVGHLSVLEHGTVSFYFTGVSRSLTHELIRHRHFSYSQLSQRYVPERKAAMVEPDVIAEDPELHARFQAAAEASVAAYNELLAGLEEKFADLPNATLRRKQARQAARAILPNATETRIVVTGNYRAWRHFIAMRATESADVEIRALAVECLRQLHKAVPNVFGDFEISALPDGTEIASSPYVTEG
>CP025990.1|AUS80213.1|4669284_4669866_-|toxin-antitoxin-system-HicB-family-antitoxin
MDLSPYVAQLRKDLASAASAGDEETRRAATLLAGAVEPAVRLALMNALSDLAAEVTSNLDDHVVDVRISGRDVNVVVTPVGGPATESAEHPESAPPPPPPPPPPPAEGDISRITLRLFDEIKSKAEQAAATQGVSLNSWVAQAVQGALHGPWSGQAHRGGPPPRGERPGGQEDRRGTGRDRDGDGGVHGWVRG
>CP025990.1|AUS80212.1|4668271_4669186_-|hypothetical-protein
MTTDSDHDGQARQARYRRVEFEADGPVDLDIGVADCDVTVELGGASGGSAELRHAPDRGAGWAGGLLDIVGWATERAEGDSVDLAAKAIERTRIDHGDNRLLVRSPQSLPLRSVPMSLLVRVPSSSRVTVRTETGDVTVTGEAAGLDLRAGTGEVRADASDGRVDVGSGAGRVRLTRVRGETTVHSGAGEVELTEVSGRTAIRTGLGRVRLGTVRGDVTVRSGAGDITVTEAVEGNLRLTTGTGQLRIGIARGVHTELDVHAPLGGFRSALAVSDRPPSDGEVGLRVRARSGMGRVLVASTGDS
>CP025990.1|AUS80211.1|4666993_4668229_+|winged-helix-turn-helix-domain-containing-protein
MQTMSGSAATRLALGAQGFTDARPTGRPTRHHLKRVLKRVRLLQLDSVNVAVRAHYMPVLSRLGPYDRALLDDAAWTDSPARPRLLVEDWAHEASLVPVADWPLLGWRREAYRQRYEHHRAALEERSPGLADEVLDAVKRLGPISAGALERELTGAGSGSRGGWWNRSDTKNMCEYLFGVGALTTGTRRSFERRYDLPERVLPPTAFARTPPDRDEAARELVLRSAGALGVATEPDLRDYYRLPTSASKAAVAELVDAGSLEAVEVRGWDRAAYRLPGASVPRRVEGRALLCPFDPLIWRRERAERLFGFHYRIEIYVPESRRVHGYYVFPFLLDGELVARVDLKADRAAGVLRVPGAFLEEGRPVARTAAELAGALREMAEWLELDGVVVGGRGDLADPLARAVAGSDGG
>CP025990.1|AUS81890.1|4666096_4666702_-|GNAT-family-N-acetyltransferase
MAVADVRPAVTADASEITRIQRVTWQAAYADLLPPEVLATLDTPDAEEAWREALAQPTARVFVATEGEWTVGFCAAGPAPAEAVASADGALPEDSDRVGLVSVLLVEPRWGRRGHAGRLLAAAGEALRGEGAERGVTWLPQSDTASESFYRKAGWEPDGTARTLDAGGRPFREVRLTGPLDIPLVERGGGAGGVPSDADPR
>CP025990.1|AUS80210.1|4665640_4666090_+|hypothetical-protein
MRARAAAVVLTAALVVYLVLLAGRAWLLVTSGDPVAVLLGAAVLALPLLGVWMVVATWRFGARTARLGERIVAEGGLPDESHLPTMPSGRIERDAADEFFAARRAELDEAPGDWRSWFKLARAYDLAGDRRRAREAMRRAVDLERGTTG
>CP025990.1|AUS80209.1|4664870_4665644_+|4-hydroxy-tetrahydrodipicolinate-reductase
MSTVDQQSGPVRVGVIGARGRMGSQVCQAVEGAPDLELVAALDSGDPLERLTGAGAQVVVEFTRPDVTMTNIRFCVDHGIHTVVGTSGFDDERLASLSELVAEHPGVGVLVAPNFAIGAVLAMRFAELAARHYESAEIIELHHPRKVDAPSGTADRTARLIAGARRDAGLGAAPDATTQQVPGARGADIAGVPVHSVRLSGLVAHQEVLFGSEGETLTIRHDSVDRSSFMPGVLLAVREVGARPGVTVGIDPLLGLR
>CP025990.1|AUS80216.1|4677726_4678494_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MPVASLLVGLTGRLVVTGDVPARLRGRPLLLAANHIGNFDVLVLVAACRRIGVAPRFMATGGLFDAPVLGPVMRRCGHVRVNRGKDTAGDAIGTAVSALGSGAPVLVYPEGRISLDPGLWPERGKTGVARIALASGAPVVPVSQWGAHEAVCWGTLRIESRADLWILFRSWFQAMRRRPTFRVHFGHPVELSGLESGRPGDAVRARDRIMRAISRGLRPLRHREPLRPAFHDGTRPVTGRSPWSPEADRERAKAG
>CP025990.1|AUS81893.1|4678908_4681248_+|DNA-translocase-FtsK
MARGVGGMARAVGRTRDLDPAHRRDGAAMVLIALAIVTAAGVWWRAGGPVGEWVDVALRSFAGLAAAVVPVVLFGTGIAMFRHQSLPDARMRHVLGSLLMGLAALGILHLSTGAPQEPAAWRESAGVIGFVAGGPLGQGLTGPVAIALLALIVCFGLLVFTGTPVSRIPERWRELVGDEEPAPSRGPRPRRTRAAEVGTREDVEPEEDRPARRPRRRAAAREDADPVGDTGEAEEVAAAEPARPAAAAAAARAVAHPPAADQETGAGTAERAKGTPFTVRAVEGDYRLPPPELLRAGDPPKARSRANDAMIDAIQGVLEQFKIDARVTGFTRGPTVTRYEVELGPGVKVEKITALTKNIAYAAATDNVRLLAPIPGKSAVGIEVPNSDREMVRLADVLHSPTALGDAHPLVIGLGKDIEGHMLTANLAKMPHLLCAGSTGSGKSSFVNSMLVSLLARATPTEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQANRVRHIDDFNRKVRDGEITTPPGSEREYRPYPYILAIVDELADLMMTAPRDVEEAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGAEKLIGMGDGLYLPMGASRATRMQGAFVSDEEISQVVAYTKDQAQPQYTEGVTAAKPGEQREIDPDIGDDLEVLLQAAELVVTSQFGSTSMLQRKLRVGFAKAGRLMDLLETRGVVGPSEGSKARDVLVKPEDLGGLMASIKGAPPAEEPAG
>CP025990.1|AUS80217.1|4681531_4683178_+|phosphoenolpyruvate--protein-phosphotransferase
MAEVVLNGVGVSPGRAAGPVVRITEPVLDPPAGPPPVDPTAEAARIRPAGAAVAGRLRAQAARAEGESAEVLETTAVMAEDPSLLGKAEQLVASGPLPAARAVHEAAEEFVTALRAAGGYMAERARDVIDVRDRLVTELLGRAAPGIPVLDQPSVLLARDLAPADTAGLDPSVVLALVTEEGGPTSHTAILARSLGIPAVVACQGVLELDPAALVVDGGLGTVVEAAPEVTVVTADRPPEAHWDGVGRTSDGHQVALLANVGSAPDSAEAVRAGAEGVGLFRTEFCYLGATREPSAQDQHEAYRRVLAPFRGKPVVVRTLDAGADKPIPFLDQHGEPNPALGVRGLRLGRVHEDVLDRQLGAIVAAATDSGAVVSVMAPMVATPAEAAWFAARARAAGVERVGVMVEVPSAVLTADEILDVVDFVSVGTNDLAQYTLAADRQLGAVAQLTDPWQPGLLRLLRLLGRSAGAAGKPVGVCGEAAADPDLAAVLVGLGVSSLSMNHPALAPVGARLAGVDLARCRAAAEAALAAAEPSAARAAARLELARR
>CP025990.1|AUS80218.1|4683337_4684444_-|NAD(P)/FAD-dependent-oxidoreductase
MSTSQVTRVDVVVIGAGQAGLSSAHSLARAGLPPGSGFVVLDGATRPGGAWGERWPTLTMRTVHGIHQLPGMPVPAVDESEAAAVAVPRYFADYEREFDLPVRRPVMVRSVRPGPAGRLLVDSDDGGYAARALINATGTWRRPFWPRYPGQELFGGRQLHTADYRGPEEFAGQRVVVVGGGSSAVQLLLEIDEVASTVWVTRNPPDIRRGPFDQDRGREAVASVDREVRAGRPPGSVVRATGLVLPPDALAAWEAGRLARRPMFQRLTPTGVAWPDGHHEDVDVVLWCTGFRPALDHLAPLRLRTRHGGIVMDGTRVVADPRVHLVGYGPSASTVGANRAGRDAVRDIRRLLAAPAADGAGDDLPRAG
>CP025990.1|AUS80219.1|4688465_4691858_-|hypothetical-protein
MVTPRGVRTLLCAALVTLPLAALPTATAAPDPGPPAGAALPEDGPAASSRIEPDLWAAPGGSAADLGFTVSSSTTAVAPGLELTEFARFDPNGWVEGDVLTADLSGTGLRPTYLHPGSVSDRAPLSEQVASAGAVAGVNADFFDINATGAPLGVGIDDGTLRHAPADGRNLTATFTEEGLASLTEVFLEASVTLPGGESVPASNFNSPVVADGGIGVFTPLWGESDRTTAVVGADRVSEVEVRDGRVVAVREAPSAGPVADGSQFLLGRDGGADLLGALSVGDAVGLDVDVRSDVEDIAVAVGGNRVLVRDGAVLPVDDVALHPRTAVGFSEDGERFWLVTIDGRQASSRGMTERELGHYLRSLGAHHALNLDGGGSSTMLARPVGDAEPSVRNSPSDGGERTVPNGLGLVTPEGSGELTGYRVEPAVTGADSERVLGGLGRRLVAHGHDETGAAVAATPRWSVTPQRLGQVGRGVFRARPGAPGVDGPRTVTVAAGRDGTRSEVELRVLGTPVRLGTDIGQVALAGDGAVGHFTVLGYDGDGFGTWVEPADVSLDYDRDVVRITPHEDGFAVTALVPSGSTVVEATVGGLRAAVGVSVGTEDHVLSSMDDLAAWQATGFPAVVDSAISSAPGRDGGTGIALDYGFTGTTATRAAYVAARGDLALPAGTQRIGVWINGDGRGAWPRLDLRDNGGVATILDLAAAVDWTGWRYVEATVPGGLAGPLRVHRVYLAETDGNSQYEGRVVFDDLTAAVSPVAEVPPPGAPRDPSVLGAAPRGPAGGLRVAVVSDAQFTADSPDGEAARQARRSFREALASEPDVVLINGDLVDRGFAEDFAVARRILDEELGDSVPWYYVPGNHEISGPGDISEFQAAFGAPFQVADHGGIRMVLLNSAYGTLRGGGFDQVEMLRDALDSAVSDPDVDGVLVAMHHPTVDPGPAANSRLADSREADLIAGWLTEFELESGKPAAVITAHAGLFHASRVDGVPYWINGNAGKGPSARPESGGFTGWSLLHLDPSREELPMRVEMRPHVDGLSVEVPDELAIGGTGEVVAEVHQDGRTVPVAYPVAGSWSGSDGLHVAGASTSEPGPEHVASFDPATGQVRGLRAGTASLELAVNGVTERVRVTVR
>CP025990.1|AUS80220.1|4692110_4692641_-|hypothetical-protein
MSSRSPRRALRTLLASVLATMALLVGGGVAHASLPPAELRQVTDDYLFTQSLPSFVQLRSQRPHAPQLDWSSDGCSYSPDEPFGYEFLNSCHRHDFGYRNYKLQNRFTSANRKAIDDRFRDDMYSVCSSAVCRRTADVYYWAVRAFGGSGTTTAEAIERALHEPSVQARLAELGSR
>CP025990.1|AUS80221.1|4693360_4693942_-|amino-acid-N-acetyltransferase
MLNVQVAEDEPLVVRRARVGDVRAVKRLVDAYAGKVLLAKELVALYEGVQEFWVAEIGGDIVGCGALHVLWEDLAEIRTVAVAPEAAGRGVGRAVVSRLVEVAIELGLRRIFVLTFETAFFARLGFRAISGTPVSAEVYEEMRHSVDEGVAEFLDLPYVKPNTLGNSRMLLELPAEEQKSPGSTSPGPRVTPG
>CP025990.1|AUS80222.1|4694053_4695499_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MPTPEPPRRVAVVTLGCSRNEVDSEELAGRLSGAGWELVDTDASGEDTPSVVLVNTCGFIESAKKDSVDTLLAAADTGAKVVAVGCMAERYGKELADSLPEADAVLGFDHYPDMANRLDEVLAGNAVASHTPGDRRRLLPISPVERPSALAGSAEQVAVPGHAWGPRVPRRRLDKSPVAPLKLASGCDRRCSFCAIPSFRGSFVSRPTDDVVAEAEWLAVSGVRELFLVSENSTSYGKDLGDLRALEKLLPRLAEVPGIDRVRVSYLQPAETRPGLVSAIATTPGVASYFDLSFQHSSESVLRRMRRFGSTESFLGLVESVRALSPTAGLRTNVILGFPGETEDDVAELERFLTAARLDVVGVFGYSDEENTEAAGFPDKLDPDLISERVTRVSALVEELTAQRAAERVGEEVTVLVERTADEEGDCTGRAEHQGPEVDGECVLTDAEGIEVGQFVRATVVDSEGVDLIVRPQEVLTRGYP
>CP025990.1|AUS80223.1|4695495_4696176_+|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MTAAEDATMDSTGTPTGADWAKAEAPEPADPAGVTPTAVPVVNIANALTVFRLVLVPFFLVALFVGAEGGTWRLVAAGLFALAAITDRLDGDLARRRGLITDFGKIADPIADKALIGAALVGLSVLGELPWWVTIAIGVRELGVTLLRFWVIRHGVIPASRGGKLKTLVQIVAIGLYVLPLSDGFDLVRWSVMAVALLLTLATGIDYVVRAVRMRARGRRALAGTA
>CP025990.1|AUS80224.1|4696172_4696700_+|damage-inducible-protein
MSRADDHSPLPGFGLDEERLTLLLDRLRQRGETVAAAESLTAGLVTGLLTSVPGASAVVRGGLVVYGTDLKGSLAGVDTAVLDEHGPVHPEVARRLAEGARRRCGADWGLGLTGVAGPDPQNGLPPGLVHVAVAGADEVTVRTLRLSRSRHGVRAAAVRAALDALGAALDRAPPA

Crispr_ID: CP025990_30

• CRISPR_ID: CP025990_30
• CRISPR_location: 4939768-4940057
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP025990_30

Consensus_repeat	Method
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRISPRCasFinder
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CRT
GTCCTCATCGCTCCTACGAGGAGTTCCAAC	PILER-CR

spacers of CP025990_30

>30.1|4939798|34|CP025990|CRISPRCasFinder,CRT
TGCGATCCCTCCCCGGTCGGCCGCCGCCGGGCGC
>30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR
GTGCCGGCGTACGCCCGCCGGCACCGGCGGGTCAA
>30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR
GTGGCGCTGGACCGGGTCGAGGCGGCTCGGCCCCT
>30.4|4939992|36|CP025990|CRISPRCasFinder,CRT,PILER-CR
CCAGGAGTTCACGGCGGCAGTCGGCCGGATGTGCAT

CRISPR arrays and Neighbor proteins around CP025990_30

CRISPR arrays

The CRISPR arrays of CP025990_30

>merge|CP025990|30|4939768-4940057|CRISPRCasFinder,CRT,PILER-CR
GCAGGAACTCCTCCTAGGCGCGATGAGGACTGCGATCCCTCCCCGGTCGGCCGCCGCCGGGCGCGTTGGAACTCCTCGTAGGAGCGATGAGGACGTGCCGGCGTACGCCCGCCGGCACCGGCGGGTCAAGTTGGAACTCCTCGTAGGAGCGATGAGGACGTGGCGCTGGACCGGGTCGAGGCGGCTCGGCCCCTGTTGGAACTCCTCGTAGGAGCGATGAGGACCCAGGAGTTCACGGCGGCAGTCGGCCGGATGTGCATGTTGGAACTCCTCGTAGGAGCGATGAGGAC

>CP025990|30|29|4939768-4940057|CRISPRCasFinder
GCAGGAACTCCTCCTAGGCGCGATGAGGAC	TGCGATCCCTCCCCGGTCGGCCGCCGCCGGGCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GTGCCGGCGTACGCCCGCCGGCACCGGCGGGTCAA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GTGGCGCTGGACCGGGTCGAGGCGGCTCGGCCCCT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCAGGAGTTCACGGCGGCAGTCGGCCGGATGTGCAT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

>CP025990|30|23|4939768-4940057|CRT
GCAGGAACTCCTCCTAGGCGCGATGAGGAC	TGCGATCCCTCCCCGGTCGGCCGCCGCCGGGCGC
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GTGCCGGCGTACGCCCGCCGGCACCGGCGGGTCAA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GTGGCGCTGGACCGGGTCGAGGCGGCTCGGCCCCT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCAGGAGTTCACGGCGGCAGTCGGCCGGATGTGCAT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

>CP025990|30|23|4939832-4940057|PILER-CR
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GTGCCGGCGTACGCCCGCCGGCACCGGCGGGTCAA
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	GTGGCGCTGGACCGGGTCGAGGCGGCTCGGCCCCT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC	CCAGGAGTTCACGGCGGCAGTCGGCCGGATGTGCAT
GTTGGAACTCCTCGTAGGAGCGATGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80412.1|4944665_4945184_+|hypothetical-protein	unknown	unknown	gnl|CDD|373062
CP025990.1|AUS80414.1|4945559_4945997_+|hypothetical-protein	unknown	unknown	gnl|CDD|373062
CP025990.1|AUS80402.1|4927751_4930085_-|hypothetical-protein	unknown	unknown	gnl|CDD|199906
CP025990.1|AUS80401.1|4927026_4927560_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|380293
CP025990.1|AUS80411.1|4944376_4944637_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80408.1|4940484_4940790_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80404.1|4932289_4934614_-|alpha-xylosidase	unknown	unknown	gnl|CDD|236731
CP025990.1|AUS80399.1|4926326_4926674_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80415.1|4945981_4946314_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80413.1|4945132_4945627_+|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW	unknown	unknown	gnl|CDD|380284
CP025990.1|AUS81914.1|4938858_4939377_-|transcriptional-regulator	unknown	unknown	gnl|CDD|294013
CP025990.1|AUS80410.1|4942493_4943666_+|citrate-synthase/methylcitrate-synthase	unknown	unknown	gnl|CDD|99862
CP025990.1|AUS80403.1|4930783_4932142_-|hypothetical-protein	unknown	unknown	gnl|CDD|365903
CP025990.1|AUS80406.1|4936231_4937242_-|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
CP025990.1|AUS80405.1|4934707_4936096_-|beta-glucosidase	unknown	unknown	gnl|CDD|274539
CP025990.1|AUS80407.1|4938311_4938767_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP025990.1|AUS80400.1|4926673_4927039_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80409.1|4941122_4942403_-|excisionase	unknown	unknown	gnl|CDD|376311

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80414.1|4945559_4945997_+|hypothetical-protein	gnl|CDD|373062	pfam14428, SCP1201-deam, SCP1.201-like deaminase. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Streptomyces SCP1.201. Members of this family are predicted to function as toxins in bacterial polymorphic toxin systems.	6.71945e-14
CP025990.1|AUS80402.1|4927751_4930085_-|hypothetical-protein	gnl|CDD|199906	cd10318, RGL11, Rhamnogalacturonan lyase of the polysaccharide lyase family 11. The rhamnogalacturonan lyase of the polysaccharide lyase family 11 (RGL11) cleaves glycoside bonds in polygalacturonan as well as RG (rhamnogalacturonan) type-I through a beta-elimination reaction. Functionally characterized members of this family, YesW and YesX from Bacillus subtilis, cleave glycoside bonds between rhamnose and galacturonic acid residues in the RG-I region of plant cell wall pectin. YesW and YesX work synergistically, with YesW cleaving the glycoside bond of the RG chain endolytically, and YesX converting the resultant oligosaccharides through an exotype reaction. This domain is sometimes found in architectures with non-catalytic carbohydrate-binding modules (CBMs). There are two types of RG lyases, which both cleave the alpha-1,4 bonds of the RG-I main chain through a beta-elimination reaction, but belong to two structurally unrelated polysaccharide lyase (PL) families, 4 and 11.	0
CP025990.1|AUS80409.1|4941122_4942403_-|excisionase	gnl|CDD|376311	pfam00285, Citrate_synt, Citrate synthase, C-terminal domain. This is the long, C-terminal part of the enzyme.	1.15558e-56
CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase	gnl|CDD|380293	NF033451, BREX_2_MTaseX, BREX-2 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated with PGL (phage growth limitation), a type 2 BREX (bacteriophage exclusion) system. The phage resistance appears not be restriction, but does manage to inhibit phage replication.	0
CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW	gnl|CDD|380284	NF033442, BREX_PglW, BREX system serine/threonine kinase PglW. Members of this family are PglW, a predicted serine/threonine kinase of the Pgl (phage growth limitation) system (now called BREX type 2) and the BREX type 3 system.	0
CP025990.1|AUS80404.1|4932289_4934614_-|alpha-xylosidase	gnl|CDD|236731	PRK10658, PRK10658, putative alpha-glucosidase; Provisional.	0
CP025990.1|AUS80413.1|4945132_4945627_+|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	4.10042e-11
CP025990.1|AUS80406.1|4936231_4937242_-|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.28364e-53
CP025990.1|AUS81914.1|4938858_4939377_-|transcriptional-regulator	gnl|CDD|294013	cd00383, trans_reg_C, DNA-binding effector domain of two-component system response regulators. Bacteria and some eukaryotes use two-component signal transduction systems to detect and respond to changes in the environment. The systems consists of a sensor histidine kinase and a response regulator. The former autophosphorylates a histidine residue on detecting an external stimulus. The phosphate is then transferred to an invariant aspartate residue in a highly conserved receiver domain of the response regulator. Phosphorylation activates a variable effector domain of the response regulator, which triggers the cellular response. This C-terminal effector domain belongs to the winged helix-turn-helix family of transcriptional regulators and contains DNA and RNA polymerase binding sites. Several dimers or monomers bind head to tail to small tandem repeats upstream of the genes. The RNA polymerase binding sites interact with the alpha or sigma subunit of RNA polymerase.	2.23723e-25
CP025990.1|AUS80403.1|4930783_4932142_-|hypothetical-protein	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.0838e-57
CP025990.1|AUS80412.1|4944665_4945184_+|hypothetical-protein	gnl|CDD|373062	pfam14428, SCP1201-deam, SCP1.201-like deaminase. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Streptomyces SCP1.201. Members of this family are predicted to function as toxins in bacterial polymorphic toxin systems.	2.0356e-12
CP025990.1|AUS80405.1|4934707_4936096_-|beta-glucosidase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	0
CP025990.1|AUS80407.1|4938311_4938767_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	4.6861e-05
CP025990.1|AUS80410.1|4942493_4943666_+|citrate-synthase/methylcitrate-synthase	gnl|CDD|99862	cd06109, BsCS-I_like, Bacillus subtilis (Bs) citrate synthase CS-I_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and OAA to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. The overall CS reaction is thought to proceed through three partial reactions and involves both closed and open conformational forms of the enzyme: a) the carbanion or equivalent is generated from AcCoA by base abstraction of a proton, b) the nucleophilic attack of this carbanion on OAA to generate citryl-CoA, and c) the hydrolysis of citryl-CoA to produce citrate and CoA. This group contains proteins similar to BsCS-I, one of two CS isozymes in the gram-positive B. subtilis. The majority of CS activity in B. subtilis is provided by the other isozyme, BsCS-II (not included in this group). BsCS-I has a lower catalytic activity than BsCS-II, and has a Glu in place of a key catalytic Asp residue. This change is conserved in other members of this group. For E. coli CS (not included in this group), site directed mutagenesis of the key Asp residue to a Glu converts the enzyme into citryl-CoA lyase which cleaves citryl-CoA to AcCoA and OAA. A null mutation in the gene encoding BsCS-I (citA) had little effect on B. subtilis CS activity or on sporulation. However, disruption of the citA gene in a strain null for the gene encoding BsCS-II resulted in a sporulation deficiency, a characteristic of strains defective in the Krebs cycle. This group contains proteins which functions exclusively as either a CS or a 2MCS, as well as those with relaxed specificity which have dual functions as both a CS and a 2MCS. Many of the gram-negative species represented in this group have a second CS isozyme which is in another group.	2.18414e-135

Protein sequences

>CP025990.1|AUS81914.1|4938858_4939377_-|transcriptional-regulator
MTVTITVRTDVEEAASVTGRLVRAVRRAVDLSAASLTVDGVTVSRRCPASREDAGRGDVGTRPSGPLHIVLPARRVTRAGVDVPLTRMEFDLLVFLCENPGVVHQRSDLVTRVWGAPGRSSERTIDVYVRRIRSKLGVDCPLITTVRGVGYRVDDPTLVVLHHAVASGSARS
>CP025990.1|AUS80407.1|4938311_4938767_+|hypothetical-protein
MPPTTEPPRPAASRPGAGTPSGAGTVHHRGTASPPGGEPDAVPPPTPTAAPRPQDMRPPPRWGTSASPRPGRTTTPPPRADQPEVTDMDIPRRKASDDVPRPGAGDEPSTPATEADDAPIGANPRCPGLDGTVLPSLGEDCERNPRGYVWD
>CP025990.1|AUS80406.1|4936231_4937242_-|LacI-family-transcriptional-regulator
MVTIKDVAERAGVSTSTVSYVLSGARKISAGTREVVRQAIDELGYHPHASARALRAARTRVLALALPQTTRSYRAVDGRFIHDLSVAAVRQGHDLLLMTAQEGVPGLRRIARGRLADAGILMAVDLDDPRIEAMREANFPIAVVGRPTTTLGTPWTDLDFEQAAVLALGDLASAGHHRLAYLAVTEQEIQARRSYAAHGLAGARRAAGQLAGSVEILHSTSDRLELRRRLAALFAMPDAPTALAVQDAAAARVVVDALAEQGMRVPSDVSVVLIGTLPDDPEHVAFRRVELPVERMAEHATALAIAAVDDPTSGTRVLIPPDLLPGPSVAPPREAG
>CP025990.1|AUS80405.1|4934707_4936096_-|beta-glucosidase
MSDLPVLPPDFVFGVATASYQIEGAVREGGRGPSIWDTFSHTPGRVARGETGDVACDHYHRYREDVALLRDLGVDSYRFSTAWPRVQPEGRGPANAAGLDFYDRLVDELLAAGVAPALTLYHWDLPQALEDAGGWRARDTAHRFADYASLVVGRLGDRVARWITLNEPFCSAFIGHAEGRHAPGAREGTPALAAAHHLLLAHGLAVSCLRDAGAGEVGITLNPERITAVGGGEEEIAAARRAETLRNLAFTDPILGARYPEWERETWGPLADGSYRRDGDLAVIAAPLDFLGVNYYAPSRVAPAPRVEADPARRTAWDVGAVAAGWPGARTTEMGWPVVPSTLTDLLTGLVERYPGLPPLYITENGSAEADQVGPDGVVHDEGRVDYLREHLGAVARAVDLGVDVRGYYAWSLLDNFEWAYGYDRRFGLVHVDYDTQTRTPKDSYHWYRRAIAGHRERSARG
>CP025990.1|AUS80404.1|4932289_4934614_-|alpha-xylosidase
MKFTNGVWLMRDGVRASYATEARDVVTTGETVTVHAATRAVRHRGDTLYGPVLTTHWWTPAPDVIAVRTTHFAGGRPRSPEFSLAVEPDTTAKVERVGPVVELTSGRLSLRLDTSAEWSLDFLAEGRVLTRTGRKGTGIAVTEEDRHYSVAQLSLGVGELVYGLGERFTPLVRNGQVVDIWQADAGTGSEQSYKNVPFYLTNRGYGVFVNEPGQTSFEVASEHTGRVQFSTEGQTLEYLVIYGPTPKEILSRYTALLGRPALPPAWSFGLWLSTSFTTSYDEETVTGFIEGMRDRSIPLSVFHFDCFWMREYQWCDFEWDPAVFPDPPGMLRRLHDRGLRVSVWINPYIGQKSPLFEEGLREGYLLRRPNGDVWQWDLWQPGLAIVDFTNPAARAWYSDKLRGLLAMGVDCFKTDFGERIPTDVVYHDGSDPVRMHNYYTHLFNQTVFEVLREQRGDGEAVVFGRSATAGGQRFPVHWGGDSESTFESMAESLRGGLSLGLSGFGFWSHDIGGFEGTPDPGVFKRWLAFGLLSSHSRLHGSRSYRVPWEFDEESVEVARFFTELKCRLMPYLYGAAGQAADHGWPVMRSMGFGFPDDPACDYLDRQYLLGDDLLVAPVLSADGEVEYYVPSGRWTHLVTGEPMEGPGWRRERHGFLGLPVLVRPGAVVPLGGRSDRPDYDYTRGLTLRVGWSPELTRTRTAVPTLAGETGVEFETTRTGATLTVRVVAGAAAGWRVLVVGVAAVTAVRGGTWEPHEQGVLLSATGAELSVVVAD
>CP025990.1|AUS80403.1|4930783_4932142_-|hypothetical-protein
MIVSARSTDAGVLVAHLACFPPRLGTAEPESREDHILMKHQRTPRALVCGALAALLALGAPPALADPGAGSAAPPDTNGDSDRSAMLDALRLPVEAAGYPGIQLRVRDGADEEVLTTGVADLGTGVPTPPDGVFRAASVTKSLVATLVLQLVEEDRLALADPLAEHLPGSVPTADRVTVEQLLNHTSGLTDYLEDAEFDDVAEYSRRTYTPWDLVRFSGAQDPVGEPGGEFSYANINYVLLGLVVESVTGEPLEVLLRERVFEPAGMANSSFPLTERELPGPHSLGYYRLAGDPAGEWRELTELNPSFAWAAYALVSDTADVNRFYRALFGGELVSPESLALMTDGVPTTDPTLFPQYGLGLQTLNTVCGVPLVGHTGGIPGFLTYSFGTLDGERHVTVSGNAWAGDESVALFHLGVVNAINLEFCGEEWAPVGNVPTVLTEQPPLGAALNG
>CP025990.1|AUS80402.1|4927751_4930085_-|hypothetical-protein
MTMSNSGRISGARPTRRWRTAVTAVIATVFAALGVPAAANAATVDPNAYYQLVNRHSGKALDIEARGTGDGVNAVQWTRNSGTNQQFRFLPSGDGWYRIQARHSGKVLDLYEFDVADGARVVQWADLNGHNQQFRLADSAGGHVRLINRLSGKALEVWEWSTEDGARVSQYSDHDGHNQQWQLVPVDGGGTQPPGQARQVEDLNRGLISARSGNGNLVSWRLLGTDPAGVAFNLYRGSTRVNSSPITDSTNYFDGGASATASYTVRAVVNGTEQGASEPSLRFGGGNYLDVPLQVPSGGRTPDGVDYTYSANDASVGDLDGDGQYEFVVKWDPSNSKDNAHSGHTGNVFVDAYRLDGTRLWRIDLGRNIRAGAHYTQFQVYDFDGDGRAEVAMKTADGTVDGAGRVIGNANADHRNSSGYVLAGPEFLTVFDGRTGAALSTVDYLPARGNVSDWGDNYGNRVDRFLAGTAYLDGQRPSLIMSRGYYTRTVIVAWDFRDGSLTRRWTFDSNSAGSQYRGQGFHSLSIADVDGDGRDEIVFGAMVIDDDGTPLWNTGYGHGDALHVGDFVPSRPGLEVFGVAENSNQPSSWLVDARTGQPIHTTPANGDNGRGVAGDIWAGSPGAEMWSSRVDGMRDTQGRNVGRKPSSTNFLIWWDGDPVRELLDQTRIDKYGPNGDTRLLTANGVASNNGTKATPALSGDLFGDWREEVVWRTSDSRALRIYTTTDLTDLRIPTLMHDTQYRVAIAWQNTAYNQPPHPSFFIGDGMAPVPQPNVYYP
>CP025990.1|AUS80401.1|4927026_4927560_+|hypothetical-protein
MPPVSEDQPEVPAWERELRALFLTFVEHLPPKDAPAEEQLAYRERWAECFDEVADTLDEIQRTAALLARSARDSLDMLRRLAGQYPPVAAEVPAPRVEGQTGTAGRLAAWWSRAWRRSSPTPAAPRRVRLEFRRCRTCRNGGWWPDGQEWCWDCTAAGEWRRLRTAARHAAVGRYPG
>CP025990.1|AUS80400.1|4926673_4927039_+|hypothetical-protein
MVPQVVAAPAQGAGALFTVEMPGTGPMLMVDLGSLCVQVRFHQDGQDREHLDRFLSELSGEAARALAWLRSQPRHTHGLLDVDSARTALAGYLPATPPEDPPGGAHHWRAPEPTDEGECHR
>CP025990.1|AUS80399.1|4926326_4926674_+|hypothetical-protein
MASGGGARLRAGHDEVFPHGALVMRVGRVMEPRSREERARGAARVPELDPGTGHCQWLVTVIDQAAEALPGTNLRPVVFEGLTAAPRNDSGQCGPPAAGRGQRCRAWPTGERDTP
>CP025990.1|AUS80408.1|4940484_4940790_-|hypothetical-protein
MAAVVAALLGGTTLAAAASPAENTATAVAPTQMRCGDNFTDTRLGTTVMRDLTYYNCGTTTVWRKATGYPPASCRQIGPGERRSLAYVNTFYYWLGPSVAC
>CP025990.1|AUS80409.1|4941122_4942403_-|excisionase
MTGRTGHDANEAGQEGVRHHLTTAQVADRLGVRQETVYAYVSRGLLTSHREPGRRGSRFSVAEVEALAGAGRERRTSTGVLERIRTEITLLADDRLHYRGRDAVDLASSCSAEQVARLLWTGNLTDHRPFAAPDELVRAARRADRALPPAARLTDRIRVLLTTVAISDPLRFDLDEGSVTNRTETLVGVLVRALPLVPGASGPSSAALADQLWPRLTAEEPTEEAVDHLRAALILLADHDLAASTLAARLAASTRGPLYSVVSAGLGAVEGTAHGAASGVAYRFLREALDDTLGALADRLRVESALPGFGHRVYTARDPRAEALLGRLRESAEGSPRLAQAVDVVDTIADRLRDRPGGFPNIDLALAAMQHGYRMRADAGEAVFAVARIAGWVAHALEEYREPGVRFRPAGVYVGPPPTSDADDDR
>CP025990.1|AUS80410.1|4942493_4943666_+|citrate-synthase/methylcitrate-synthase
MSGTTTNSPRDTIRASEVPPGLRGVVVTSTTLGDVRGEEGFYHYREYSAVDLAETRSLEDVWFLFVEGRLPDAEERAAFVEEVAPLRRLPAELLAVLPAIAGSSRGDLLAGLRAALSLAGAVRGVRPLWDSSGEQRRADALWVAAVTPTILAALYRLGVGLEPLEPRQDLSAAANWLYQVTGEEPAEHEVAAINRYLVSTVDHGFNASTFTGRVVASTGADLVAAVVAAVGAFSGPLHGGAPDRALDALDEIGSPDRIDGWVRGRVQAGDRIMGFGHPVYRTADPRAVMLRRTALELGGDLADFAVRVETRVVELLAELKPERRLHANVEFYAGVVMELCGLPRAMFTPTFATSRVIGWCANLLEQAGESSIIRPAARYVGPPAPVPVPV
>CP025990.1|AUS80411.1|4944376_4944637_+|hypothetical-protein
MDMQQIIGGLQAASTLLEPYGLSQEQGRMDEVTGHLAVLNGTARHGEVLAQLEQIRQSIAMAADQQQQLREQLVRLMATFQGGFGI
>CP025990.1|AUS80412.1|4944665_4945184_+|hypothetical-protein
MVHGTHDPAPADEPPQGRSLPHPSNTPWEAALGTGVAWVAWARDQLPERPRGRGQTTGIILGGSDGSGERMVSGHEPESDLAGLILATSDVFPEHRLRDLAIADVARHVETKLAVRQAEAGVTHTVVVLNNRMCDGLYGCTEAVAAILPRGFSMTVWEPGRSRPTIIEGKAT
>CP025990.1|AUS80413.1|4945132_4945627_+|hypothetical-protein
MGTRAQPTDHHRRESHVTVVVTAIIDNDRYYARTEEERAVLIRRMVDEEHPGWASLVYVWDRPAGEGSGRLAWPAWQLRVSAEPGLGVGALNWVGPVPSDELGPWDTLNPTPIVGVAVEFDGSVPSYFPPSAVLPIDDVRRAVAEHFNTGRRPECVQWQPGYRF
>CP025990.1|AUS80414.1|4945559_4945997_+|hypothetical-protein
MRNTSTRAAGRSACSGSRAIGSEPTTGINLKGPEGSGERVVSGRGPESDVVGLILATSDLFPEHPLRDRAIADAARHVETKLALRQAESGVTHAVVVVNNLMCEGPYGCTEAVAAILPRGFSMTVWEPGRSRPTTVEGKATWQSS
>CP025990.1|AUS80415.1|4945981_4946314_+|hypothetical-protein
MAVVVTAIIDNVRHYRAPGPSIRASGGAPPRQASHPGAASPAGLSLRSLRRRTLLAVVLLDEPHLSLNPVAIGADLSVSPSLAEYARPRLVGTQRFAVAITAPRGKPFSE
>CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW
MRNGPEARRGGSQGQAPPQWCQERRSPYPWEQDGLDHVRRLLPRAEPYRAWATFSFTSSTGRVHECDLLVAAPNGLHLVELKGHPGRVVNRAGTWKVYDGTSTRPRHLRNPLHLTDLKSKELKSRLDWAAKELGKKTKVPRISASVFLSAPGLVSELDEQQNTSVYGRDEDCQGLPWIWRDLLARPPANRDRVTPEFSRDILPELLDTIDIRAATAHLRFDDEWELSHEVLDMGLTWEDRLAERTGIVREQGRVRIYLTERQADAERRESVTRAARREYQLLQGITHRGIAQAVQIRENQGGPAILFHHRASDLRLDSYLDLFDEQLTFETRLDMVRQLAEAVQYAHSRSLYHRALSARSVYVSTKDGKTGPVLRIIDWQAAARDFDTSGHTSLGRSSPEAEHLASATEAYLAPEFDAPYADPVDLDIFGLGALAYLLLTGQPPAPQRAALIDRLAKHGGLHPYAVSDGISDALDAVVFSATQADVAQRLDSADAFLKRLDSAERESLPDAVPVIADPLAVSPGQALDSDWTVERILGTGATARALLITHVGEDENGDPLLERRVLKVALDEAKAVRLLDEAEALRKVGGGMVVKLLAPPRQLGGRAVLDLEYAGGTDPESGTLGELLRAEGKLSYHYLERYGRDLFTALDQLQAQGVRHRDLKPDNFGVYRRADRSTQLMLFDFSLAKASELDVKAGTRAYLDPHLGTERRPRYDDHAERYAAAVTLHEMASGRRPVWGDGVTDPRTTNDATPTLAVDLFDPALRDELTAFFHRALHRDVNKRFDGFRQMEEAWRGVFTVADAASPVTTPGTVGLGEATLEETRNAHAEAAALDTPLDAAGLTPRAVSVAQSFDAVTVGDLLNVPLYRIAKARGAGALVRKELNRRHKQWTSALCQDNGPGPRAVADQGRLSVDDLAQLLTGYEGGRRGSKRGDVIRLTLGLPTEHGPPRPWPTQSEVADELGINQTSVSWHYRNALRAWAKEPRLQELRDELVRLVTDAGRIMTANELAAGLRTRFGSVDQDAERVAARALAVVRAGVDTEVDAGMAPGAPDGGPRLTVYRRGGRLLIALESLRGVEEPSASELADYAVRLGERADDLVSRDPLPGRGVVVRELRAVTPPEGLTALADTRLADLAAAMSENAAASPRVELYPRDLNLARAVRISQAAAGVRRDHGITMEDVLARVRARFPALALGRDLTHVVVEEALQQAGFPLEYDTTTRRFRPRATELPGFVTSSSTAMTRHERMRAAGIDPTAVVEAKLCSALERGGFLALTVRGVHVPGAAQAVATAYAGRLRPVNLDSEFLTAFQALVDERGQDWEKVRRLDARLAATGEISRGFASYVTAAWNRLRARLMEFAADDGVLFLHEATLLARYFDEGGHDLLTGVQNAARRPREAPHGLWLLCPADSALDAPRLGTRLVEVLGDSERVVLDSEFLAALRTGSAA
>CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase
MAGRGLGSNDLVKDLRRQVTLLEDDLRERSDQEVEFAKALRGEYDEAFDAERTGATYEAWRDERVTQVAAAWVLGTVFVRFCEDNGLIGVPFIAGPGERLAEAEERHEAHFRQRPQDNDRDWIIEAFHHLSDAHPTTAGLFDRRHNPLWEVTPSFEAATALLQFWRRRDDDGEIRYDFTDLSTRFLGDLYQDLSEAARKKYALLQTPEFVEEFILDLTLEPAVEEFGLDGLRTIDPACGSGHFLLGIFHRVLEKWRAAEPGTDGWQLIRRSLGSVHGCDKNPFAVSIARFRLLHAALEAAGVRRLDNAPEFPINIAVGDSLLHGRGAAGIQDDLFTTPETYAYVTEDVNGFVRSCDLLGRSSYHVVVGNPPYITVKDKTENEAYRRRYDACSGTYALSVPFAQRLFQLAVRRDGDERGAGYVGQITANSFMKREFGRGLIEKFFFGKVNLTHVIDTSGAFIPGHGTPTVILIGVNHPPRRGSVRAVLGVRGEPSEPPVPAHGRVWTAILEQLDKPSSESDWISVEDVDSERFARHPWTLSGGGAGVVLNSIVRSTPHVLSRRVNEVGFGVVTREDNAYMLTEGVLRRRGVGVDSQRFLVEGDAVRDYCIYNPTLALWPYDPSTLKPVASPESEKLLWPNRMLLRGRVAYGKTQLERGLGWFEYSMFFVKRYEVPLSISFAFVATHNHFVLDRGGKVFKQTAPVIKLAAGASEDEHLELLGVLNSSTACFWLKQVSHDKGNGGEGGGIASEGWERFYEFTGTKLKEFPLPAQLPLTYGRALDTLAQRLAEREPAAVAAAGVPSRERLDAARGEHERIRRQMIAVQEELDWTVYHSYSLLNDTEVAEVVAPDLDDLPEVKLGERAFEIVLARRVAAGELETAWFERHRSTPITDIPTHWPAWYRAIVQARIDTIEKRRDIALIERPECKRRWSTETWEKKESEALRGWLLDRCERRDLWFGLRDGFEQPRTLTVNQLADAFRGDTDTHEVAERYAIDHLGKPELTLAQVLERLVADQHVPYLAALRYKDPGLRKRAQWEDVWNQQREEDRTGQNLDIPVPPKYTSGDFRKVSYWAHRGKLDVPKERFISYPDASPDSDPSLLLGWAGWDHKDQAQALVNIINDRSFEAGWDAARLTPLLAGLAEIMPWVKQWHGAEDEEWGGVPADEYAAFLDEQRGKYQLTERELTSWRPEPRMRGRRGNAKDGQGA

Crispr_ID: CP025990_31

• CRISPR_ID: CP025990_31
• CRISPR_location: 4968613-4968886
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: cas3

Consensus repeat of CP025990_31

Consensus_repeat	Method
CGGCTCACCCCCGCTTGCGCGGGGCTTTC	PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CRISPRCasFinder
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CRT

spacers of CP025990_31

>31.1|4968642|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
TAGCAGGGTCCGGTGTGTGGGGCGGCCTGGTG
>31.2|4968703|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GACCTGGGCCATGTCGTGTCCAACCGGACCGT
>31.3|4968764|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGTCACCCGGGACGTGTCAACGGGGAGGTTTC
>31.4|4968825|32|CP025990|CRISPRCasFinder,CRT
CAGGACGAGCACGGCCAGGATCGCGCCCACCA

CRISPR arrays and Neighbor proteins around CP025990_31

CRISPR arrays

The CRISPR arrays of CP025990_31

>merge|CP025990|31|4968613-4968886|PILER-CR,CRISPRCasFinder,CRT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGTAGCAGGGTCCGGTGTGTGGGGCGGCCTGGTGGAAAGCCCCGCGCAAGCGGGGGTGAGCCGGACCTGGGCCATGTCGTGTCCAACCGGACCGTGAAAGCCCCGCGCAAGCGGGGGTGAGCCGGGTCACCCGGGACGTGTCAACGGGGAGGTTTCGAAAGCCCCGCGCAAGCGGGGGTGAGCCGCAGGACGAGCACGGCCAGGATCGCGCCCACCAGAAAGCCCCGCGCAAGCGGGGGTGAGCCGT

>CP025990|31|24|4968613-4968824|PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TAGCAGGGTCCGGTGTGTGGGGCGGCCTGGTG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GACCTGGGCCATGTCGTGTCCAACCGGACCGT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GGTCACCCGGGACGTGTCAACGGGGAGGTTTC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG

>CP025990|31|30|4968613-4968886|CRISPRCasFinder
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TAGCAGGGTCCGGTGTGTGGGGCGGCCTGGTG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GACCTGGGCCATGTCGTGTCCAACCGGACCGT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GGTCACCCGGGACGTGTCAACGGGGAGGTTTC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CAGGACGAGCACGGCCAGGATCGCGCCCACCA
GAAAGCCCCGCGCAAGCGGGGGTGAGCCGT

>CP025990|31|24|4968613-4968885|CRT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	TAGCAGGGTCCGGTGTGTGGGGCGGCCTGGTG
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GACCTGGGCCATGTCGTGTCCAACCGGACCGT
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	GGTCACCCGGGACGTGTCAACGGGGAGGTTTC
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CAGGACGAGCACGGCCAGGATCGCGCCCACCA
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80417.1|4954670_4958498_+|PglY-protein	unknown	unknown	gnl|CDD|380283
CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD	unknown	unknown	gnl|CDD|380280
CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW	unknown	unknown	gnl|CDD|380284
CP025990.1|AUS80421.1|4965807_4965996_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|380293
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS80418.1|4958494_4961173_+|BREX-2-system-phosphatase-PglZ	unknown	unknown	gnl|CDD|380288
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	unknown	unknown	gnl|CDD|224759
CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	gnl|CDD|224122
CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein	unknown	unknown	gnl|CDD|379237
CP025990.1|AUS80415.1|4945981_4946314_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	unknown	unknown	gnl|CDD|214834
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	2e-15	51.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	7.84843e-15
CP025990.1|AUS80417.1|4954670_4958498_+|PglY-protein	gnl|CDD|380283	NF033441, BREX_BrxC, BREX system P-loop protein BrxC. BrxC is a P-loop-containing protein, and probable ATPase, from BREX (bacteriophage exclusion) systems of type 1.	0.000137698
CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD	gnl|CDD|380280	NF033438, BREX_BrxD, BREX system ATP-binding protein BrxD. BrxD is an ATP-binding protein found in types 2 and 6 of BREX (bacteriophage exclusion) phage resistance systems.	0
CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW	gnl|CDD|380284	NF033442, BREX_PglW, BREX system serine/threonine kinase PglW. Members of this family are PglW, a predicted serine/threonine kinase of the Pgl (phage growth limitation) system (now called BREX type 2) and the BREX type 3 system.	0
CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase	gnl|CDD|380293	NF033451, BREX_2_MTaseX, BREX-2 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated with PGL (phage growth limitation), a type 2 BREX (bacteriophage exclusion) system. The phage resistance appears not be restriction, but does manage to inhibit phage replication.	0
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.7686e-13
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	5.47817e-12
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.25775e-05
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.73014e-09
CP025990.1|AUS80418.1|4958494_4961173_+|BREX-2-system-phosphatase-PglZ	gnl|CDD|380288	NF033446, BREX_PglZ_2, BREX-2 system phosphatase PglZ.	0
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	0.00135798
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.82967e-17
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	gnl|CDD|224122	COG1201, Lhr, Lhr-like helicases [General function prediction only].	1.13133e-117
CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein	gnl|CDD|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.86034e-28
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	5.29271e-07
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	gnl|CDD|214834	smart00823, PKS_PP, Phosphopantetheine attachment site. Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.	6.72887e-21
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	6.12669e-15

Protein sequences

>CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein
MAASGSDAAVVAMATDLAGLRAQAQAGILPPIWRSLVRIPTRRAAGRQEGTAAGWGARLAALSVEERQREILSLVRSKVSVVLGHDDVAAVQARRSFKDLGFDSLTAVELRNTLTAATGLRTTPNTKNRVDPTSNHRRSVMCRSSPRSRCSPPPKRWARPLVDHGVIGRTDPGGQPPDR
>CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein
MFEFDAGALGLIALHPLVPASDVDLLHRWVTQDRARFWGMTGLSRAEVLETYRYVDSLPTHHAFLARRRGVPVGLVQTYEPAEDPMGDYYEVRRGDIGFHLFALAGSLGRPLLVAARERGVPRLPVGHERQRHPAPSPARTRSTPGWPLR
>CP025990.1|AUS80421.1|4965807_4965996_+|hypothetical-protein
MMLAEFVPALNGHGVPASGTTENAGKLAARLVRTAQLIPGTLGRESEENGRGVDVGDIEWSA
>CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase
MTDPVTRLHPVVVHHVVNTLGWRTLRPLQEQAIEPVLNGKDALLLAPTAGGKTEAAFLPVLSAMEDQGWTGVSVLFLCPLKALLNDLLPRLASYGSWVGRRVDLWHGDVSTSKRRKILRDPPDVLLTTPESLESMLVSPNVDHHRFLSGVRAVVIDEVHAFAGDDRGWHLLAVLERLSVLTQRPIQRIGLSATVGNPSELLAWMQGSGQGARPGIVVAPHSTARTGPPPGDIELDYVGSVDNAAAVIAALHRGEKRLVFCDSRQLVEEIGAALRARGVTTHLSHASLSLDERRRAERAFADSRDCVIVATSTLELGIDVGDLDRVVQINTPSTVASFLQRLGRSGRRAGTTRNCLFLAIREEALLWSSALLLLWGRGYVEAVQPPADPRHIIAQQTLALCLQEQAIDRATWQHAWNDLPPFDSGADAVLGYLLGEGFIEQDGPMMFIGPEAERRFGRRNFMDMTAVFTAPPQFTVLEGRREVGRADPALLTEKVEGPRLLLLAGRSWKVTWIDWKRRRCFVEPADYGGRARWLAPGTGGVSFAMARAARDVLLGADPPVVLTQRAQRLLSELRDDRDGSVHPAATVITRSHHATRWWTWAGFRANATLTASLAWVAEEKRTFDDVSIRLRGDLTRESWRTGSREALERVCLPEVDERALRGLKFADALPPHLAEATLATRMADVDAARALLGGAVRFVAR
>CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD
MTATSEARRREIIDALRRGTVPQNGLDLLAVGLDRFDAAIDENLVTVASGGAAFHAIRGEYGAGKTFFARWLAEKAKRRGLATAEIQISETETPLHRLETVYRRLTERLTTATHQPSALRAVIDSWLYTLEEQVLESADVEPEDEVALARRVDELLENRLADVARTTPAFAAALRGYRRAVEAGDGATAEAIVAWLGGQKAVAAAARRTAGVRGDLDHFAALGFLQGLLLILRDCGHPGLLLVLDETETLQRVRGDVREKGLNALRQLLDEIDTGRFPGLFLVLTGTPAFFDGQQGVQRLPALAQRLATDFTTDARFDSPRAVQLRLPGFDHDRLRELGRKIRDLYAVGARHPQRVVDVVDDDYLGVLARALVGELGGHVGVAPRIFLRKLVADVLDRVDEYAEFDPRKHYQLTVTTHELVDDEKRVVTSADDVPLNLP
>CP025990.1|AUS80418.1|4958494_4961173_+|BREX-2-system-phosphatase-PglZ
MSAPPTVDRRIVEAMVEDWLPHANGRRLLLVYGRYSDGGTSFTLVRGSERVRVRVTDQHSVLGIVEVWQDHQRRRVENELLVVATSVPDDQLGWELRAHAIGRSTRTVDRARIVAQRFGAVSVDTRIRRDTWLVDALLDAEPPEGWPRGGSVLTRDTAIRSLIGARLGPRILGDGALDAGALLDWTRDPAGPVRFASLSEAERAGLVDWLVEAVGEAAVVLMRLVAEGRGSDVMPLGVVGAAATDPGATVDTAFAFGSLIGGTRTEEVRAFTAAVAGTLQRWVSEAASSRTGDAARHRVMEVVRRADRIADAANLTESLAENDLLPSTFTRRLRALAGALAHPARARSEHLNHALSAVRDHALARLEPARVRPAEMAARLARWLAEPTPEVTSVAAGISGQMNTWSWVDRAVTALAQGDPSDDPVVGQAYRAVCEAARKRRDALDEEFATHVARWTQHASAQESAGCLLIEQVLADVVAPLKGKPAPLLIVLDGMSGAVAVDLAEQLAGNLWHEVTPDAGRRTAAVAALPSVTRVSRASLLTGQLGVGGQADEEKGFRAFWQHQHRKTAFLFHKADIPGEDGYRLSDSLLGAISDSTAVVGVVLNTVDYALDQGREGDRTQWSLRDVTYLPELLDAARSYGRPVVLTSDHGHVLARPGSERTSAPGAESARWRTGEPKAGEIAVTGPRVMYGQDDLVVPWREDIRYTSAKNGYHGGVSLAEMTVPVLAFLPPGGAEPAGWTVLSPEVVQPDWWTGRTLTTELGTGKRGGSRKSRATEDVVPLFPVEPATVSLGTQVVATEIYQGQCHFVPRAPDGKVVADVIDAVVSADGILSTAAVTTVAGRAARRPEFFVTTLQRLLNVDGYPVLSVVDGGQRLKLDVEVLRTQFGVRGP
>CP025990.1|AUS80417.1|4954670_4958498_+|PglY-protein
MNDRYLREVLDLPESVHAGDFKVDLTGGFSETEARVDEYVVTDQLRGAFDQALGVVGKAMRDESAHAAYLHGSFGSGKSHFLTVLHAILNNHAVARAKPALQPVFAAHDEWLHGKKFLMVPYHLVGASDIDSAILGGYVATVRRQHPDHPTPAVYRADAMLEDARKQRRFLNDDRNFADWLGDGNSASTTASHGGDVDDLDVIEGTEIGGWTSSELDRAFSAPAGDPVRDALVSALLSGPMSSYVRGASGDAAAFIPLENGLSVISHHARDLGYDGLILFLDELILWLQAHMADQQFVNTQVNTLVKLIESGDADRGLPIVSFISRQRDLSKLVGEDVTGAEVKNLEGQVHYLAGRFDTISLEDRNLPAIIKERVLKPLPGGREILDQAFASIESSKAGDREILLDASGATGADWQDFRDVYPLSPALLNVLVALSGALQRERTGLKLLQEMLRRRRDDMKVGQLIPLGDLWDVLADGTGEAFTDHLRKEAEAGHRFYLKARNHLRDRFGEGTQLFEAMDRYIKTLLLAALAPDVPALTRLTGARLNALNLGSIRSRTVPPGSLVVTKLRDMQAEFGELRSDNERDPAFRLQLSDVDIDPLLEDVGEQDTLGARRIWTKKRLWSQLGVDNTEDFVAEREVVWRGTRRTAEFVFANVRDGRDLPDIQFTPSVPGRIRVILDHPFDDADQSPLSDAARVTHLRRSGLNAPTLVWLPHFFSPRRSAQLGRLLKIRYLLERDRLTDYAATYSEETRVKIRHQLQAQRDNLETQLVAALRQLYGIAQADESTIGKEVGEDGHVRSLLEGYTPRLTGGTTFEDNALVLADGLFDTLHPKHPDFDPQRNRKAIGLADLRTALSWIGRALEDGQRRVVVDRAHLALVKRVVHPLELGEVSDGPLNVSTEWRRRIEQAATKHGVTGDYRVEDIRSWIEELGYTGLGRAVSGLIITTYALLADRAWLLHGSPLREPPDLDRIGPGHSLRAQALPTAEEFDRARQRAAVLFGVHVPETLFTRNVNRLAEAVRQKAEVLEGPAADVRRELDRHGAALGIADARDVPRVVSSRDAANLLARITATTGDATALVRQLASAHHATADETLAVAIKSSREVRAALGGFDWSLLDSLRQFTGRGDSVGDRADELLREIAEVSQADQFTRDLLPLLNAVRHRVVALVNEAARLVGNQTLPTGPDSRPTSSGAVSQSNGVERGAAAAPSPEPERHTVSGGRAKISASAVERELDRLVSEFGAEIRAYARGNPGAEFRLSWSVVGERPGGEDTAE
>CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase
MAGRGLGSNDLVKDLRRQVTLLEDDLRERSDQEVEFAKALRGEYDEAFDAERTGATYEAWRDERVTQVAAAWVLGTVFVRFCEDNGLIGVPFIAGPGERLAEAEERHEAHFRQRPQDNDRDWIIEAFHHLSDAHPTTAGLFDRRHNPLWEVTPSFEAATALLQFWRRRDDDGEIRYDFTDLSTRFLGDLYQDLSEAARKKYALLQTPEFVEEFILDLTLEPAVEEFGLDGLRTIDPACGSGHFLLGIFHRVLEKWRAAEPGTDGWQLIRRSLGSVHGCDKNPFAVSIARFRLLHAALEAAGVRRLDNAPEFPINIAVGDSLLHGRGAAGIQDDLFTTPETYAYVTEDVNGFVRSCDLLGRSSYHVVVGNPPYITVKDKTENEAYRRRYDACSGTYALSVPFAQRLFQLAVRRDGDERGAGYVGQITANSFMKREFGRGLIEKFFFGKVNLTHVIDTSGAFIPGHGTPTVILIGVNHPPRRGSVRAVLGVRGEPSEPPVPAHGRVWTAILEQLDKPSSESDWISVEDVDSERFARHPWTLSGGGAGVVLNSIVRSTPHVLSRRVNEVGFGVVTREDNAYMLTEGVLRRRGVGVDSQRFLVEGDAVRDYCIYNPTLALWPYDPSTLKPVASPESEKLLWPNRMLLRGRVAYGKTQLERGLGWFEYSMFFVKRYEVPLSISFAFVATHNHFVLDRGGKVFKQTAPVIKLAAGASEDEHLELLGVLNSSTACFWLKQVSHDKGNGGEGGGIASEGWERFYEFTGTKLKEFPLPAQLPLTYGRALDTLAQRLAEREPAAVAAAGVPSRERLDAARGEHERIRRQMIAVQEELDWTVYHSYSLLNDTEVAEVVAPDLDDLPEVKLGERAFEIVLARRVAAGELETAWFERHRSTPITDIPTHWPAWYRAIVQARIDTIEKRRDIALIERPECKRRWSTETWEKKESEALRGWLLDRCERRDLWFGLRDGFEQPRTLTVNQLADAFRGDTDTHEVAERYAIDHLGKPELTLAQVLERLVADQHVPYLAALRYKDPGLRKRAQWEDVWNQQREEDRTGQNLDIPVPPKYTSGDFRKVSYWAHRGKLDVPKERFISYPDASPDSDPSLLLGWAGWDHKDQAQALVNIINDRSFEAGWDAARLTPLLAGLAEIMPWVKQWHGAEDEEWGGVPADEYAAFLDEQRGKYQLTERELTSWRPEPRMRGRRGNAKDGQGA
>CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW
MRNGPEARRGGSQGQAPPQWCQERRSPYPWEQDGLDHVRRLLPRAEPYRAWATFSFTSSTGRVHECDLLVAAPNGLHLVELKGHPGRVVNRAGTWKVYDGTSTRPRHLRNPLHLTDLKSKELKSRLDWAAKELGKKTKVPRISASVFLSAPGLVSELDEQQNTSVYGRDEDCQGLPWIWRDLLARPPANRDRVTPEFSRDILPELLDTIDIRAATAHLRFDDEWELSHEVLDMGLTWEDRLAERTGIVREQGRVRIYLTERQADAERRESVTRAARREYQLLQGITHRGIAQAVQIRENQGGPAILFHHRASDLRLDSYLDLFDEQLTFETRLDMVRQLAEAVQYAHSRSLYHRALSARSVYVSTKDGKTGPVLRIIDWQAAARDFDTSGHTSLGRSSPEAEHLASATEAYLAPEFDAPYADPVDLDIFGLGALAYLLLTGQPPAPQRAALIDRLAKHGGLHPYAVSDGISDALDAVVFSATQADVAQRLDSADAFLKRLDSAERESLPDAVPVIADPLAVSPGQALDSDWTVERILGTGATARALLITHVGEDENGDPLLERRVLKVALDEAKAVRLLDEAEALRKVGGGMVVKLLAPPRQLGGRAVLDLEYAGGTDPESGTLGELLRAEGKLSYHYLERYGRDLFTALDQLQAQGVRHRDLKPDNFGVYRRADRSTQLMLFDFSLAKASELDVKAGTRAYLDPHLGTERRPRYDDHAERYAAAVTLHEMASGRRPVWGDGVTDPRTTNDATPTLAVDLFDPALRDELTAFFHRALHRDVNKRFDGFRQMEEAWRGVFTVADAASPVTTPGTVGLGEATLEETRNAHAEAAALDTPLDAAGLTPRAVSVAQSFDAVTVGDLLNVPLYRIAKARGAGALVRKELNRRHKQWTSALCQDNGPGPRAVADQGRLSVDDLAQLLTGYEGGRRGSKRGDVIRLTLGLPTEHGPPRPWPTQSEVADELGINQTSVSWHYRNALRAWAKEPRLQELRDELVRLVTDAGRIMTANELAAGLRTRFGSVDQDAERVAARALAVVRAGVDTEVDAGMAPGAPDGGPRLTVYRRGGRLLIALESLRGVEEPSASELADYAVRLGERADDLVSRDPLPGRGVVVRELRAVTPPEGLTALADTRLADLAAAMSENAAASPRVELYPRDLNLARAVRISQAAAGVRRDHGITMEDVLARVRARFPALALGRDLTHVVVEEALQQAGFPLEYDTTTRRFRPRATELPGFVTSSSTAMTRHERMRAAGIDPTAVVEAKLCSALERGGFLALTVRGVHVPGAAQAVATAYAGRLRPVNLDSEFLTAFQALVDERGQDWEKVRRLDARLAATGEISRGFASYVTAAWNRLRARLMEFAADDGVLFLHEATLLARYFDEGGHDLLTGVQNAARRPREAPHGLWLLCPADSALDAPRLGTRLVEVLGDSERVVLDSEFLAALRTGSAA
>CP025990.1|AUS80415.1|4945981_4946314_+|hypothetical-protein
MAVVVTAIIDNVRHYRAPGPSIRASGGAPPRQASHPGAASPAGLSLRSLRRRTLLAVVLLDEPHLSLNPVAIGADLSVSPSLAEYARPRLVGTQRFAVAITAPRGKPFSE
>CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein
MGLLSACASAEQGTAVAVGPTVGSSLSGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESASFDDVGLSYACSYRLPSGGLALMAIDLNWKRSVDQLDLTNYTSEETVNSVSTTRAAAASSSAGVGSSARSSAAAWMSP
>CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEMTALGFDPETATFDDVGLSHDCRYRFPGGERPVMTIHLNWMRGVDQLNLTNYTVEEIGVGPLRALRIIDEIPSEHCQISVDLSEQAHVSFFVHYAGTVERACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVELTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEVTALGFDPESASFNDVGVSYSCNYRPPAGGTPLMYIGLDWKLSIDQLNLSNFIAEETSVGPLRALRITDKIDPESCQISLALSEQAHVSIFVKFGGTTEQACAIAEETAAAVEPSLPRSPG
>CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein
MVLLSACASAEQGTAVAVGPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPETARFDDVGLSYDCVYRLAHEARPLMAIHLNWMRSVDQLSLTNYTVEEIGVGPLRALRIIGKTASEHCQISVDLSEQAHVSVYVHYAGTVEHACALAEETAGAVEPLLPRSSG
>CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein
MAEATGVGLADLSEKTADLVAVGYVVWSGEPGNRVLRMTPAGRMVALDLLPAVEAFLAELSGVSSTP
>CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein
MQVDGEFGRWRKASRSGPQVECVEVGSNADHVAIRDTKNRGGGTLVVDHPTFGAFLTAVKDKRF
>CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein
MQAQQQPRWRTSSHSGSQSDCVEVACEPDVVSIRDTKNRDGGTLVVDRAAFGAFVKAVKTERL
>CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator
MASKAQARALGAELRECRKQARVTMAEVARLIGCSTATMSLTETGKRLPPVEDVAAILAVLSVTGAKRERLVRMAREAAVEPRWLGVGIPGLAPQVTGMAELERTSVRITAVAPNLVPGLLQTANYARAVFAGSDVNPSEIEARTTFRMGRQRALDEVTYVALVDESVLRRPVGGARVIRDQLEHLVEMAGRPNITIQVLPMSLGWHDALEGPFVILEGEKTAPVVHLEHKRSGLFLDEDDADEVQTYMRSAANLQQRALTARQSVELIAAVHDDWSTNAGAAATEVANV
>CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein
MNHAEWRVLVTAHIVRNAHSQTASCIVSVDPANLVALTLVQSTVGLASSHARLLASLLTTPRSGTVTTLCANEDLVSQLTVTPGATLTHPARRPTGLIALDTLDTAHPVALLLEPEAATTMARALRTAASRLEGRVGAR
>CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein
MASLPIEQVRRAVAEYFRTGRRPDCVQRQPGDWY

Crispr_ID: CP025990_32

• CRISPR_ID: CP025990_32
• CRISPR_location: 4969102-4969496
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: cas3

Consensus repeat of CP025990_32

Consensus_repeat	Method
CGGCTCACCCCCGCTTGCGCGGGGCTTAC	PILER-CR
GAAAGCCCCGCGCAAGCGGGGGTGAGCCG	CRISPRCasFinder
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	CRT

spacers of CP025990_32

>32.1|4969131|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGACGGACCGTCTGACGTCAGGGCGTCGGCCC
>32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGCTCGCGGGTCATCGTCACCGGTCGGCTCAA
>32.3|4969253|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCGAGGCAGACCCACTCGGGCCGGGGGGCGCT
>32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTCCACCGCCGCCAATCCAGTCGGCCCCGGGG
>32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
ATCGTGCAGCGTCGCCCGGCCGGCAACACGGC
>32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCCTTGAACCCGATTGGGTCAGACGAAACCCG

CRISPR arrays and Neighbor proteins around CP025990_32

CRISPR arrays

The CRISPR arrays of CP025990_32

>merge|CP025990|32|4969102-4969496|PILER-CR,CRISPRCasFinder,CRT
GTAAGCCCCGCGCAAGCGGGGGTGAGCCGTGACGGACCGTCTGACGTCAGGGCGTCGGCCCGTAAGCCCCGCGCAAGCGGGGGTGAGCCGGGCTCGCGGGTCATCGTCACCGGTCGGCTCAAGTAAGCCCCGCGCAAGCGGGGGTGAGCCGGCGAGGCAGACCCACTCGGGCCGGGGGGCGCTGTAAGCCCCGCGCAAGCGGGGGTGAGCCGGTCCACCGCCGCCAATCCAGTCGGCCCCGGGGGTAAGCCCCGCGCAAGCGGGGGTGAGCCGATCGTGCAGCGTCGCCCGGCCGGCAACACGGCGTAAGCCCCGCGCAAGCGGGGGTGAGCCGTCCTTGAACCCGATTGGGTCAGACGAAACCCGGTAAGCCCCGCGCAAGCGGGGGTGAGCGG

>CP025990|32|25|4969102-4969496|PILER-CR
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	TGACGGACCGTCTGACGTCAGGGCGTCGGCCC
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GGCTCGCGGGTCATCGTCACCGGTCGGCTCAA
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GCGAGGCAGACCCACTCGGGCCGGGGGGCGCT
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GTCCACCGCCGCCAATCCAGTCGGCCCCGGGG
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	ATCGTGCAGCGTCGCCCGGCCGGCAACACGGC
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	TCCTTGAACCCGATTGGGTCAGACGAAACCCG
GTAAGCCCCGCGCAAGCGGGGGTGAGCGG

>CP025990|32|31|4969102-4969496|CRISPRCasFinder
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	TGACGGACCGTCTGACGTCAGGGCGTCGGCCC
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GGCTCGCGGGTCATCGTCACCGGTCGGCTCAA
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GCGAGGCAGACCCACTCGGGCCGGGGGGCGCT
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GTCCACCGCCGCCAATCCAGTCGGCCCCGGGG
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	ATCGTGCAGCGTCGCCCGGCCGGCAACACGGC
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	TCCTTGAACCCGATTGGGTCAGACGAAACCCG
GTAAGCCCCGCGCAAGCGGGGGTGAGCGG

>CP025990|32|25|4969102-4969496|CRT
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	TGACGGACCGTCTGACGTCAGGGCGTCGGCCC
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GGCTCGCGGGTCATCGTCACCGGTCGGCTCAA
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GCGAGGCAGACCCACTCGGGCCGGGGGGCGCT
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	GTCCACCGCCGCCAATCCAGTCGGCCCCGGGG
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	ATCGTGCAGCGTCGCCCGGCCGGCAACACGGC
GTAAGCCCCGCGCAAGCGGGGGTGAGCCG	TCCTTGAACCCGATTGGGTCAGACGAAACCCG
GTAAGCCCCGCGCAAGCGGGGGTGAGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80417.1|4954670_4958498_+|PglY-protein	unknown	unknown	gnl|CDD|380283
CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD	unknown	unknown	gnl|CDD|380280
CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW	unknown	unknown	gnl|CDD|380284
CP025990.1|AUS80421.1|4965807_4965996_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|380293
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS80418.1|4958494_4961173_+|BREX-2-system-phosphatase-PglZ	unknown	unknown	gnl|CDD|380288
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	unknown	unknown	gnl|CDD|224759
CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	gnl|CDD|224122
CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein	unknown	unknown	gnl|CDD|379237
CP025990.1|AUS80415.1|4945981_4946314_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	unknown	unknown	gnl|CDD|214834
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	2e-15	51.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	7.84843e-15
CP025990.1|AUS80417.1|4954670_4958498_+|PglY-protein	gnl|CDD|380283	NF033441, BREX_BrxC, BREX system P-loop protein BrxC. BrxC is a P-loop-containing protein, and probable ATPase, from BREX (bacteriophage exclusion) systems of type 1.	0.000137698
CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD	gnl|CDD|380280	NF033438, BREX_BrxD, BREX system ATP-binding protein BrxD. BrxD is an ATP-binding protein found in types 2 and 6 of BREX (bacteriophage exclusion) phage resistance systems.	0
CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW	gnl|CDD|380284	NF033442, BREX_PglW, BREX system serine/threonine kinase PglW. Members of this family are PglW, a predicted serine/threonine kinase of the Pgl (phage growth limitation) system (now called BREX type 2) and the BREX type 3 system.	0
CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase	gnl|CDD|380293	NF033451, BREX_2_MTaseX, BREX-2 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated with PGL (phage growth limitation), a type 2 BREX (bacteriophage exclusion) system. The phage resistance appears not be restriction, but does manage to inhibit phage replication.	0
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.7686e-13
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	5.47817e-12
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.25775e-05
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.73014e-09
CP025990.1|AUS80418.1|4958494_4961173_+|BREX-2-system-phosphatase-PglZ	gnl|CDD|380288	NF033446, BREX_PglZ_2, BREX-2 system phosphatase PglZ.	0
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	0.00135798
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.82967e-17
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	gnl|CDD|224122	COG1201, Lhr, Lhr-like helicases [General function prediction only].	1.13133e-117
CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein	gnl|CDD|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.86034e-28
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	5.29271e-07
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	gnl|CDD|214834	smart00823, PKS_PP, Phosphopantetheine attachment site. Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.	6.72887e-21
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	6.12669e-15

Protein sequences

>CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein
MAASGSDAAVVAMATDLAGLRAQAQAGILPPIWRSLVRIPTRRAAGRQEGTAAGWGARLAALSVEERQREILSLVRSKVSVVLGHDDVAAVQARRSFKDLGFDSLTAVELRNTLTAATGLRTTPNTKNRVDPTSNHRRSVMCRSSPRSRCSPPPKRWARPLVDHGVIGRTDPGGQPPDR
>CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein
MFEFDAGALGLIALHPLVPASDVDLLHRWVTQDRARFWGMTGLSRAEVLETYRYVDSLPTHHAFLARRRGVPVGLVQTYEPAEDPMGDYYEVRRGDIGFHLFALAGSLGRPLLVAARERGVPRLPVGHERQRHPAPSPARTRSTPGWPLR
>CP025990.1|AUS80421.1|4965807_4965996_+|hypothetical-protein
MMLAEFVPALNGHGVPASGTTENAGKLAARLVRTAQLIPGTLGRESEENGRGVDVGDIEWSA
>CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase
MTDPVTRLHPVVVHHVVNTLGWRTLRPLQEQAIEPVLNGKDALLLAPTAGGKTEAAFLPVLSAMEDQGWTGVSVLFLCPLKALLNDLLPRLASYGSWVGRRVDLWHGDVSTSKRRKILRDPPDVLLTTPESLESMLVSPNVDHHRFLSGVRAVVIDEVHAFAGDDRGWHLLAVLERLSVLTQRPIQRIGLSATVGNPSELLAWMQGSGQGARPGIVVAPHSTARTGPPPGDIELDYVGSVDNAAAVIAALHRGEKRLVFCDSRQLVEEIGAALRARGVTTHLSHASLSLDERRRAERAFADSRDCVIVATSTLELGIDVGDLDRVVQINTPSTVASFLQRLGRSGRRAGTTRNCLFLAIREEALLWSSALLLLWGRGYVEAVQPPADPRHIIAQQTLALCLQEQAIDRATWQHAWNDLPPFDSGADAVLGYLLGEGFIEQDGPMMFIGPEAERRFGRRNFMDMTAVFTAPPQFTVLEGRREVGRADPALLTEKVEGPRLLLLAGRSWKVTWIDWKRRRCFVEPADYGGRARWLAPGTGGVSFAMARAARDVLLGADPPVVLTQRAQRLLSELRDDRDGSVHPAATVITRSHHATRWWTWAGFRANATLTASLAWVAEEKRTFDDVSIRLRGDLTRESWRTGSREALERVCLPEVDERALRGLKFADALPPHLAEATLATRMADVDAARALLGGAVRFVAR
>CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD
MTATSEARRREIIDALRRGTVPQNGLDLLAVGLDRFDAAIDENLVTVASGGAAFHAIRGEYGAGKTFFARWLAEKAKRRGLATAEIQISETETPLHRLETVYRRLTERLTTATHQPSALRAVIDSWLYTLEEQVLESADVEPEDEVALARRVDELLENRLADVARTTPAFAAALRGYRRAVEAGDGATAEAIVAWLGGQKAVAAAARRTAGVRGDLDHFAALGFLQGLLLILRDCGHPGLLLVLDETETLQRVRGDVREKGLNALRQLLDEIDTGRFPGLFLVLTGTPAFFDGQQGVQRLPALAQRLATDFTTDARFDSPRAVQLRLPGFDHDRLRELGRKIRDLYAVGARHPQRVVDVVDDDYLGVLARALVGELGGHVGVAPRIFLRKLVADVLDRVDEYAEFDPRKHYQLTVTTHELVDDEKRVVTSADDVPLNLP
>CP025990.1|AUS80418.1|4958494_4961173_+|BREX-2-system-phosphatase-PglZ
MSAPPTVDRRIVEAMVEDWLPHANGRRLLLVYGRYSDGGTSFTLVRGSERVRVRVTDQHSVLGIVEVWQDHQRRRVENELLVVATSVPDDQLGWELRAHAIGRSTRTVDRARIVAQRFGAVSVDTRIRRDTWLVDALLDAEPPEGWPRGGSVLTRDTAIRSLIGARLGPRILGDGALDAGALLDWTRDPAGPVRFASLSEAERAGLVDWLVEAVGEAAVVLMRLVAEGRGSDVMPLGVVGAAATDPGATVDTAFAFGSLIGGTRTEEVRAFTAAVAGTLQRWVSEAASSRTGDAARHRVMEVVRRADRIADAANLTESLAENDLLPSTFTRRLRALAGALAHPARARSEHLNHALSAVRDHALARLEPARVRPAEMAARLARWLAEPTPEVTSVAAGISGQMNTWSWVDRAVTALAQGDPSDDPVVGQAYRAVCEAARKRRDALDEEFATHVARWTQHASAQESAGCLLIEQVLADVVAPLKGKPAPLLIVLDGMSGAVAVDLAEQLAGNLWHEVTPDAGRRTAAVAALPSVTRVSRASLLTGQLGVGGQADEEKGFRAFWQHQHRKTAFLFHKADIPGEDGYRLSDSLLGAISDSTAVVGVVLNTVDYALDQGREGDRTQWSLRDVTYLPELLDAARSYGRPVVLTSDHGHVLARPGSERTSAPGAESARWRTGEPKAGEIAVTGPRVMYGQDDLVVPWREDIRYTSAKNGYHGGVSLAEMTVPVLAFLPPGGAEPAGWTVLSPEVVQPDWWTGRTLTTELGTGKRGGSRKSRATEDVVPLFPVEPATVSLGTQVVATEIYQGQCHFVPRAPDGKVVADVIDAVVSADGILSTAAVTTVAGRAARRPEFFVTTLQRLLNVDGYPVLSVVDGGQRLKLDVEVLRTQFGVRGP
>CP025990.1|AUS80417.1|4954670_4958498_+|PglY-protein
MNDRYLREVLDLPESVHAGDFKVDLTGGFSETEARVDEYVVTDQLRGAFDQALGVVGKAMRDESAHAAYLHGSFGSGKSHFLTVLHAILNNHAVARAKPALQPVFAAHDEWLHGKKFLMVPYHLVGASDIDSAILGGYVATVRRQHPDHPTPAVYRADAMLEDARKQRRFLNDDRNFADWLGDGNSASTTASHGGDVDDLDVIEGTEIGGWTSSELDRAFSAPAGDPVRDALVSALLSGPMSSYVRGASGDAAAFIPLENGLSVISHHARDLGYDGLILFLDELILWLQAHMADQQFVNTQVNTLVKLIESGDADRGLPIVSFISRQRDLSKLVGEDVTGAEVKNLEGQVHYLAGRFDTISLEDRNLPAIIKERVLKPLPGGREILDQAFASIESSKAGDREILLDASGATGADWQDFRDVYPLSPALLNVLVALSGALQRERTGLKLLQEMLRRRRDDMKVGQLIPLGDLWDVLADGTGEAFTDHLRKEAEAGHRFYLKARNHLRDRFGEGTQLFEAMDRYIKTLLLAALAPDVPALTRLTGARLNALNLGSIRSRTVPPGSLVVTKLRDMQAEFGELRSDNERDPAFRLQLSDVDIDPLLEDVGEQDTLGARRIWTKKRLWSQLGVDNTEDFVAEREVVWRGTRRTAEFVFANVRDGRDLPDIQFTPSVPGRIRVILDHPFDDADQSPLSDAARVTHLRRSGLNAPTLVWLPHFFSPRRSAQLGRLLKIRYLLERDRLTDYAATYSEETRVKIRHQLQAQRDNLETQLVAALRQLYGIAQADESTIGKEVGEDGHVRSLLEGYTPRLTGGTTFEDNALVLADGLFDTLHPKHPDFDPQRNRKAIGLADLRTALSWIGRALEDGQRRVVVDRAHLALVKRVVHPLELGEVSDGPLNVSTEWRRRIEQAATKHGVTGDYRVEDIRSWIEELGYTGLGRAVSGLIITTYALLADRAWLLHGSPLREPPDLDRIGPGHSLRAQALPTAEEFDRARQRAAVLFGVHVPETLFTRNVNRLAEAVRQKAEVLEGPAADVRRELDRHGAALGIADARDVPRVVSSRDAANLLARITATTGDATALVRQLASAHHATADETLAVAIKSSREVRAALGGFDWSLLDSLRQFTGRGDSVGDRADELLREIAEVSQADQFTRDLLPLLNAVRHRVVALVNEAARLVGNQTLPTGPDSRPTSSGAVSQSNGVERGAAAAPSPEPERHTVSGGRAKISASAVERELDRLVSEFGAEIRAYARGNPGAEFRLSWSVVGERPGGEDTAE
>CP025990.1|AUS80416.1|4951053_4954674_+|SAM-dependent-methyltransferase
MAGRGLGSNDLVKDLRRQVTLLEDDLRERSDQEVEFAKALRGEYDEAFDAERTGATYEAWRDERVTQVAAAWVLGTVFVRFCEDNGLIGVPFIAGPGERLAEAEERHEAHFRQRPQDNDRDWIIEAFHHLSDAHPTTAGLFDRRHNPLWEVTPSFEAATALLQFWRRRDDDGEIRYDFTDLSTRFLGDLYQDLSEAARKKYALLQTPEFVEEFILDLTLEPAVEEFGLDGLRTIDPACGSGHFLLGIFHRVLEKWRAAEPGTDGWQLIRRSLGSVHGCDKNPFAVSIARFRLLHAALEAAGVRRLDNAPEFPINIAVGDSLLHGRGAAGIQDDLFTTPETYAYVTEDVNGFVRSCDLLGRSSYHVVVGNPPYITVKDKTENEAYRRRYDACSGTYALSVPFAQRLFQLAVRRDGDERGAGYVGQITANSFMKREFGRGLIEKFFFGKVNLTHVIDTSGAFIPGHGTPTVILIGVNHPPRRGSVRAVLGVRGEPSEPPVPAHGRVWTAILEQLDKPSSESDWISVEDVDSERFARHPWTLSGGGAGVVLNSIVRSTPHVLSRRVNEVGFGVVTREDNAYMLTEGVLRRRGVGVDSQRFLVEGDAVRDYCIYNPTLALWPYDPSTLKPVASPESEKLLWPNRMLLRGRVAYGKTQLERGLGWFEYSMFFVKRYEVPLSISFAFVATHNHFVLDRGGKVFKQTAPVIKLAAGASEDEHLELLGVLNSSTACFWLKQVSHDKGNGGEGGGIASEGWERFYEFTGTKLKEFPLPAQLPLTYGRALDTLAQRLAEREPAAVAAAGVPSRERLDAARGEHERIRRQMIAVQEELDWTVYHSYSLLNDTEVAEVVAPDLDDLPEVKLGERAFEIVLARRVAAGELETAWFERHRSTPITDIPTHWPAWYRAIVQARIDTIEKRRDIALIERPECKRRWSTETWEKKESEALRGWLLDRCERRDLWFGLRDGFEQPRTLTVNQLADAFRGDTDTHEVAERYAIDHLGKPELTLAQVLERLVADQHVPYLAALRYKDPGLRKRAQWEDVWNQQREEDRTGQNLDIPVPPKYTSGDFRKVSYWAHRGKLDVPKERFISYPDASPDSDPSLLLGWAGWDHKDQAQALVNIINDRSFEAGWDAARLTPLLAGLAEIMPWVKQWHGAEDEEWGGVPADEYAAFLDEQRGKYQLTERELTSWRPEPRMRGRRGNAKDGQGA
>CP025990.1|AUS81915.1|4946681_4951031_+|BREX-system-serine/threonine-kinase-PglW
MRNGPEARRGGSQGQAPPQWCQERRSPYPWEQDGLDHVRRLLPRAEPYRAWATFSFTSSTGRVHECDLLVAAPNGLHLVELKGHPGRVVNRAGTWKVYDGTSTRPRHLRNPLHLTDLKSKELKSRLDWAAKELGKKTKVPRISASVFLSAPGLVSELDEQQNTSVYGRDEDCQGLPWIWRDLLARPPANRDRVTPEFSRDILPELLDTIDIRAATAHLRFDDEWELSHEVLDMGLTWEDRLAERTGIVREQGRVRIYLTERQADAERRESVTRAARREYQLLQGITHRGIAQAVQIRENQGGPAILFHHRASDLRLDSYLDLFDEQLTFETRLDMVRQLAEAVQYAHSRSLYHRALSARSVYVSTKDGKTGPVLRIIDWQAAARDFDTSGHTSLGRSSPEAEHLASATEAYLAPEFDAPYADPVDLDIFGLGALAYLLLTGQPPAPQRAALIDRLAKHGGLHPYAVSDGISDALDAVVFSATQADVAQRLDSADAFLKRLDSAERESLPDAVPVIADPLAVSPGQALDSDWTVERILGTGATARALLITHVGEDENGDPLLERRVLKVALDEAKAVRLLDEAEALRKVGGGMVVKLLAPPRQLGGRAVLDLEYAGGTDPESGTLGELLRAEGKLSYHYLERYGRDLFTALDQLQAQGVRHRDLKPDNFGVYRRADRSTQLMLFDFSLAKASELDVKAGTRAYLDPHLGTERRPRYDDHAERYAAAVTLHEMASGRRPVWGDGVTDPRTTNDATPTLAVDLFDPALRDELTAFFHRALHRDVNKRFDGFRQMEEAWRGVFTVADAASPVTTPGTVGLGEATLEETRNAHAEAAALDTPLDAAGLTPRAVSVAQSFDAVTVGDLLNVPLYRIAKARGAGALVRKELNRRHKQWTSALCQDNGPGPRAVADQGRLSVDDLAQLLTGYEGGRRGSKRGDVIRLTLGLPTEHGPPRPWPTQSEVADELGINQTSVSWHYRNALRAWAKEPRLQELRDELVRLVTDAGRIMTANELAAGLRTRFGSVDQDAERVAARALAVVRAGVDTEVDAGMAPGAPDGGPRLTVYRRGGRLLIALESLRGVEEPSASELADYAVRLGERADDLVSRDPLPGRGVVVRELRAVTPPEGLTALADTRLADLAAAMSENAAASPRVELYPRDLNLARAVRISQAAAGVRRDHGITMEDVLARVRARFPALALGRDLTHVVVEEALQQAGFPLEYDTTTRRFRPRATELPGFVTSSSTAMTRHERMRAAGIDPTAVVEAKLCSALERGGFLALTVRGVHVPGAAQAVATAYAGRLRPVNLDSEFLTAFQALVDERGQDWEKVRRLDARLAATGEISRGFASYVTAAWNRLRARLMEFAADDGVLFLHEATLLARYFDEGGHDLLTGVQNAARRPREAPHGLWLLCPADSALDAPRLGTRLVEVLGDSERVVLDSEFLAALRTGSAA
>CP025990.1|AUS80415.1|4945981_4946314_+|hypothetical-protein
MAVVVTAIIDNVRHYRAPGPSIRASGGAPPRQASHPGAASPAGLSLRSLRRRTLLAVVLLDEPHLSLNPVAIGADLSVSPSLAEYARPRLVGTQRFAVAITAPRGKPFSE
>CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein
MGLLSACASAEQGTAVAVGPTVGSSLSGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESASFDDVGLSYACSYRLPSGGLALMAIDLNWKRSVDQLDLTNYTSEETVNSVSTTRAAAASSSAGVGSSARSSAAAWMSP
>CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEMTALGFDPETATFDDVGLSHDCRYRFPGGERPVMTIHLNWMRGVDQLNLTNYTVEEIGVGPLRALRIIDEIPSEHCQISVDLSEQAHVSFFVHYAGTVERACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVELTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEVTALGFDPESASFNDVGVSYSCNYRPPAGGTPLMYIGLDWKLSIDQLNLSNFIAEETSVGPLRALRITDKIDPESCQISLALSEQAHVSIFVKFGGTTEQACAIAEETAAAVEPSLPRSPG
>CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein
MVLLSACASAEQGTAVAVGPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPETARFDDVGLSYDCVYRLAHEARPLMAIHLNWMRSVDQLSLTNYTVEEIGVGPLRALRIIGKTASEHCQISVDLSEQAHVSVYVHYAGTVEHACALAEETAGAVEPLLPRSSG
>CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein
MAEATGVGLADLSEKTADLVAVGYVVWSGEPGNRVLRMTPAGRMVALDLLPAVEAFLAELSGVSSTP
>CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein
MQVDGEFGRWRKASRSGPQVECVEVGSNADHVAIRDTKNRGGGTLVVDHPTFGAFLTAVKDKRF
>CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein
MQAQQQPRWRTSSHSGSQSDCVEVACEPDVVSIRDTKNRDGGTLVVDRAAFGAFVKAVKTERL
>CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator
MASKAQARALGAELRECRKQARVTMAEVARLIGCSTATMSLTETGKRLPPVEDVAAILAVLSVTGAKRERLVRMAREAAVEPRWLGVGIPGLAPQVTGMAELERTSVRITAVAPNLVPGLLQTANYARAVFAGSDVNPSEIEARTTFRMGRQRALDEVTYVALVDESVLRRPVGGARVIRDQLEHLVEMAGRPNITIQVLPMSLGWHDALEGPFVILEGEKTAPVVHLEHKRSGLFLDEDDADEVQTYMRSAANLQQRALTARQSVELIAAVHDDWSTNAGAAATEVANV
>CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein
MNHAEWRVLVTAHIVRNAHSQTASCIVSVDPANLVALTLVQSTVGLASSHARLLASLLTTPRSGTVTTLCANEDLVSQLTVTPGATLTHPARRPTGLIALDTLDTAHPVALLLEPEAATTMARALRTAASRLEGRVGAR
>CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein
MASLPIEQVRRAVAEYFRTGRRPDCVQRQPGDWY

Crispr_ID: CP025990_33

• CRISPR_ID: CP025990_33
• CRISPR_location: 4974042-4974498
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas3

Consensus repeat of CP025990_33

Consensus_repeat	Method
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRT
GGGAACAGCCCCGCGTGCGCGGGGACGACTCCCGCT	PILER-CR

spacers of CP025990_33

>33.1|4974070|33|CP025990|CRISPRCasFinder,CRT
ACGAGCCGGGCGTACGCCGGCTGGGCCGGCGAA
>33.2|4974131|33|CP025990|CRISPRCasFinder,CRT
TGGGTAGGGCCCGTTCCGGATATCCCCGGCGAC
>33.3|4974192|33|CP025990|CRISPRCasFinder,CRT
CCGCGGCGGTCTGCTCGACGTCGCCGCGCGCAC
>33.4|4974253|33|CP025990|CRISPRCasFinder,CRT
ATCGAGGACCAGGTGCAGGCTGCCGGCCGGGGC
>33.5|4974314|33|CP025990|CRISPRCasFinder,CRT
TGTCGGCGACGACTGCGCCCAGGTTGAGCGCCA
>33.6|4974375|35|CP025990|CRISPRCasFinder,CRT
CCCGTCGCCAGGAATCCCGGGCGAGCTCAGCAGGT
>33.7|4974438|33|CP025990|CRISPRCasFinder,CRT
CGCAGCCGGCCCGGCGGAGGCCAGGCCGATGAT
>33.8|4974319|26|CP025990|PILER-CR
TGTCGGCGACGACTGCGCCCAGGTTG
>33.9|4974382|27|CP025990|PILER-CR
CCGTCGCCAGGAATCCCGGGCGAGCTC

CRISPR arrays and Neighbor proteins around CP025990_33

CRISPR arrays

The CRISPR arrays of CP025990_33

>merge|CP025990|33|4974042-4974498|CRISPRCasFinder,CRT,PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCCACGAGCCGGGCGTACGCCGGCTGGGCCGGCGAAGTCGTCCCCGCGCACGCGGGGCTGTTCCTGGGTAGGGCCCGTTCCGGATATCCCCGGCGACGTCGTCCCCGCGCACGCGGGGCTGTTCCCCGCGGCGGTCTGCTCGACGTCGCCGCGCGCACGTCGTCCCCGCGCACGCGGGGCTGTTCCATCGAGGACCAGGTGCAGGCTGCCGGCCGGGGCGTCGTCCCCGCGCACGCGGGGCTGTTCCTGTCGGCGACGACTGCGCCCAGGTTGAGCGCCAGTCGTCCCCGCGCACGCGGGGCTGTTCCCCCGTCGCCAGGAATCCCGGGCGAGCTCAGCAGGTGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCAGCCGGCCCGGCGGAGGCCAGGCCGATGATGTCGTCCCCGCGCATCCGGGTTGTGCGC

>CP025990|33|32|4974042-4974498|CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ACGAGCCGGGCGTACGCCGGCTGGGCCGGCGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TGGGTAGGGCCCGTTCCGGATATCCCCGGCGAC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGCGGCGGTCTGCTCGACGTCGCCGCGCGCAC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ATCGAGGACCAGGTGCAGGCTGCCGGCCGGGGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TGTCGGCGACGACTGCGCCCAGGTTGAGCGCCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCGTCGCCAGGAATCCCGGGCGAGCTCAGCAGGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCAGCCGGCCCGGCGGAGGCCAGGCCGATGAT
GTCGTCCCCGCGCATCCGGGTTGTGCGC

>CP025990|33|26|4974042-4974498|CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ACGAGCCGGGCGTACGCCGGCTGGGCCGGCGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TGGGTAGGGCCCGTTCCGGATATCCCCGGCGAC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGCGGCGGTCTGCTCGACGTCGCCGCGCGCAC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ATCGAGGACCAGGTGCAGGCTGCCGGCCGGGGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TGTCGGCGACGACTGCGCCCAGGTTGAGCGCCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCGTCGCCAGGAATCCCGGGCGAGCTCAGCAGGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCAGCCGGCCCGGCGGAGGCCAGGCCGATGAT
GTCGTCCCCGCGCATCCGGGTTGTGCGC

>CP025990|33|26|4974282-4974439|PILER-CR
GGGCGTCGTCCCCGCGCACGCGGGGCTGTTCCTGTCG	GCGACGACTGCGCCCAGGTTGAGCGC
CAGTCGTCCCCGCGCACGCGGGGCTGTTCCCCCGTCG	CCAGGAATCCCGGGCGAGCTCAGCAGG
TGTCGTCCCCGCGCACGCGGGGCTGTTCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein	unknown	unknown	gnl|CDD|236122
CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD	unknown	unknown	gnl|CDD|380280
CP025990.1|AUS80421.1|4965807_4965996_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	unknown	unknown	gnl|CDD|224759
CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	gnl|CDD|224122
CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein	unknown	unknown	gnl|CDD|379237
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	unknown	unknown	gnl|CDD|214834
CP025990.1|AUS80434.1|4985698_4985878_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein	unknown	unknown	gnl|CDD|350678

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	cas3	cd09639_cas3_CAS-I	2e-15	51.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	7.84843e-15
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	5.47817e-12
CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein	gnl|CDD|236122	PRK07877, PRK07877, Rv1355c family protein.	4.41801e-22
CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD	gnl|CDD|380280	NF033438, BREX_BrxD, BREX system ATP-binding protein BrxD. BrxD is an ATP-binding protein found in types 2 and 6 of BREX (bacteriophage exclusion) phage resistance systems.	0
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.7686e-13
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	6.12669e-15
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.25775e-05
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.73014e-09
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	0.00135798
CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.38464e-163
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.82967e-17
CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase	gnl|CDD|224122	COG1201, Lhr, Lhr-like helicases [General function prediction only].	1.13133e-117
CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein	gnl|CDD|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.86034e-28
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	5.29271e-07
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	gnl|CDD|214834	smart00823, PKS_PP, Phosphopantetheine attachment site. Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.	6.72887e-21
CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein	gnl|CDD|350678	cd17920, DEXHc_RecQ, DEXH-box helicase domain of RecQ family proteins. The RecQ family of the type II DEAD box helicase superfamily is a family of highly conserved DNA repair helicases. This domain contains the ATP-binding region.	3.09549e-104

Protein sequences

>CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein
MAEATGVGLADLSEKTADLVAVGYVVWSGEPGNRVLRMTPAGRMVALDLLPAVEAFLAELSGVSSTP
>CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein
MVLLSACASAEQGTAVAVGPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPETARFDDVGLSYDCVYRLAHEARPLMAIHLNWMRSVDQLSLTNYTVEEIGVGPLRALRIIGKTASEHCQISVDLSEQAHVSVYVHYAGTVEHACALAEETAGAVEPLLPRSSG
>CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVELTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEVTALGFDPESASFNDVGVSYSCNYRPPAGGTPLMYIGLDWKLSIDQLNLSNFIAEETSVGPLRALRITDKIDPESCQISLALSEQAHVSIFVKFGGTTEQACAIAEETAAAVEPSLPRSPG
>CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEMTALGFDPETATFDDVGLSHDCRYRFPGGERPVMTIHLNWMRGVDQLNLTNYTVEEIGVGPLRALRIIDEIPSEHCQISVDLSEQAHVSFFVHYAGTVERACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein
MGLLSACASAEQGTAVAVGPTVGSSLSGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESASFDDVGLSYACSYRLPSGGLALMAIDLNWKRSVDQLDLTNYTSEETVNSVSTTRAAAASSSAGVGSSARSSAAAWMSP
>CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein
MAASGSDAAVVAMATDLAGLRAQAQAGILPPIWRSLVRIPTRRAAGRQEGTAAGWGARLAALSVEERQREILSLVRSKVSVVLGHDDVAAVQARRSFKDLGFDSLTAVELRNTLTAATGLRTTPNTKNRVDPTSNHRRSVMCRSSPRSRCSPPPKRWARPLVDHGVIGRTDPGGQPPDR
>CP025990.1|AUS80422.1|4966204_4966657_-|hypothetical-protein
MFEFDAGALGLIALHPLVPASDVDLLHRWVTQDRARFWGMTGLSRAEVLETYRYVDSLPTHHAFLARRRGVPVGLVQTYEPAEDPMGDYYEVRRGDIGFHLFALAGSLGRPLLVAARERGVPRLPVGHERQRHPAPSPARTRSTPGWPLR
>CP025990.1|AUS80421.1|4965807_4965996_+|hypothetical-protein
MMLAEFVPALNGHGVPASGTTENAGKLAARLVRTAQLIPGTLGRESEENGRGVDVGDIEWSA
>CP025990.1|AUS80420.1|4962485_4964588_+|ATP-dependent-helicase
MTDPVTRLHPVVVHHVVNTLGWRTLRPLQEQAIEPVLNGKDALLLAPTAGGKTEAAFLPVLSAMEDQGWTGVSVLFLCPLKALLNDLLPRLASYGSWVGRRVDLWHGDVSTSKRRKILRDPPDVLLTTPESLESMLVSPNVDHHRFLSGVRAVVIDEVHAFAGDDRGWHLLAVLERLSVLTQRPIQRIGLSATVGNPSELLAWMQGSGQGARPGIVVAPHSTARTGPPPGDIELDYVGSVDNAAAVIAALHRGEKRLVFCDSRQLVEEIGAALRARGVTTHLSHASLSLDERRRAERAFADSRDCVIVATSTLELGIDVGDLDRVVQINTPSTVASFLQRLGRSGRRAGTTRNCLFLAIREEALLWSSALLLLWGRGYVEAVQPPADPRHIIAQQTLALCLQEQAIDRATWQHAWNDLPPFDSGADAVLGYLLGEGFIEQDGPMMFIGPEAERRFGRRNFMDMTAVFTAPPQFTVLEGRREVGRADPALLTEKVEGPRLLLLAGRSWKVTWIDWKRRRCFVEPADYGGRARWLAPGTGGVSFAMARAARDVLLGADPPVVLTQRAQRLLSELRDDRDGSVHPAATVITRSHHATRWWTWAGFRANATLTASLAWVAEEKRTFDDVSIRLRGDLTRESWRTGSREALERVCLPEVDERALRGLKFADALPPHLAEATLATRMADVDAARALLGGAVRFVAR
>CP025990.1|AUS80419.1|4961169_4962489_+|BREX-system-ATP-binding-protein-BrxD
MTATSEARRREIIDALRRGTVPQNGLDLLAVGLDRFDAAIDENLVTVASGGAAFHAIRGEYGAGKTFFARWLAEKAKRRGLATAEIQISETETPLHRLETVYRRLTERLTTATHQPSALRAVIDSWLYTLEEQVLESADVEPEDEVALARRVDELLENRLADVARTTPAFAAALRGYRRAVEAGDGATAEAIVAWLGGQKAVAAAARRTAGVRGDLDHFAALGFLQGLLLILRDCGHPGLLLVLDETETLQRVRGDVREKGLNALRQLLDEIDTGRFPGLFLVLTGTPAFFDGQQGVQRLPALAQRLATDFTTDARFDSPRAVQLRLPGFDHDRLRELGRKIRDLYAVGARHPQRVVDVVDDDYLGVLARALVGELGGHVGVAPRIFLRKLVADVLDRVDEYAEFDPRKHYQLTVTTHELVDDEKRVVTSADDVPLNLP
>CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein
MQVDGEFGRWRKASRSGPQVECVEVGSNADHVAIRDTKNRGGGTLVVDHPTFGAFLTAVKDKRF
>CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein
MQAQQQPRWRTSSHSGSQSDCVEVACEPDVVSIRDTKNRDGGTLVVDRAAFGAFVKAVKTERL
>CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator
MASKAQARALGAELRECRKQARVTMAEVARLIGCSTATMSLTETGKRLPPVEDVAAILAVLSVTGAKRERLVRMAREAAVEPRWLGVGIPGLAPQVTGMAELERTSVRITAVAPNLVPGLLQTANYARAVFAGSDVNPSEIEARTTFRMGRQRALDEVTYVALVDESVLRRPVGGARVIRDQLEHLVEMAGRPNITIQVLPMSLGWHDALEGPFVILEGEKTAPVVHLEHKRSGLFLDEDDADEVQTYMRSAANLQQRALTARQSVELIAAVHDDWSTNAGAAATEVANV
>CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein
MNHAEWRVLVTAHIVRNAHSQTASCIVSVDPANLVALTLVQSTVGLASSHARLLASLLTTPRSGTVTTLCANEDLVSQLTVTPGATLTHPARRPTGLIALDTLDTAHPVALLLEPEAATTMARALRTAASRLEGRVGAR
>CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein
MASLPIEQVRRAVAEYFRTGRRPDCVQRQPGDWY
>CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein
MSARTTTEARPAPASAGRPPNEKSSDFLGSGRRVLGLLARERVAMVVVLVLALASVGLSVAGPRILGYATDLVVEGTFGPAAAGIDFGALGTVLLWVLGVYLASAVFGIVQGRLTNGAVQRTAGRLRRDAQAKLARLPLRHFNGQSRGEVLSRVTNDIDNVAQSLQQVLSQVIVSLLTLVAVLAMMFSISWLLALIALVSIPAAVLVTALIGKRAQPEFAEQWKSTGELNGHVEEMYTGHALVRAFGRQREAAEVFAERNERLFRSSFRAQFISGLIQPSMMFVSNLNYVLVAVVGGLRVTSGQLTIGDVQAFVQYSRQFTQPLTQVASMANLVQSGVASAERVFDFLDAEEEEPDPAEPRRVPTVRGRVEFEHVSFRYDPDKPLIEDLSLVAEPGQTIAIVGPTGAGKSTLVNLLMRFYEVTGGRITLDGVDTAEMTRADVRATTGMVLQDTWLFGGTIAENIAYGAKDATREQVVAAAKTAHVDHFARTLPEGYDTVVDEEGGGVSAGEKQLITIARAFLANPSILVLDEATSSVDTRTEVLIQRAMAELRSGRTAFVIAHRLSTIRDADRIVVMEEGAIVEQGTHDELLASGRPPLPHRSFDTIRA
>CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein
MLIALLRVHLRPYTGRLGLLVLLQLVQTVATLYLPTLNADIIDNGVIPGDQGRILTVGAVMIGATMLQVACAAGAVYLGAHTAMSVGRDIRAAVFHRTQSFSNRELGEFGAPSLITRTTNDVQQVQMLVLMTCTLMVTAPIMCVGGIVLALNQDVPLSGLLLALVPALGLVVVTLASRLRPLFRTMQERIDGVNRVLREQINGLQVIRAFGRDDHERERFRTANTALTDTALRIGRLMAVMFPLVMFVVNVATVAVTWIGAGRIDSGAMQVGALVAFLSYLMQILMAVMMATFMFMMVPRAEVCADRIQEVLTTTGTVRPPAHPVRELPGTGGLELRDVEFRYPGAEDPVLREVSFLARPGQTTAVIGSTGSGKSTLLSLVPRLADVTAGAVLVDGTDVRDLDPALLARTVSVVPQRPYLFSGTIASNLRYGNPDATDEELWRALEIAQAADFVRSRPEGLEAPVSQGGTNVSGGQRQRLAIARAVVQRPAVYLFDDSFSALDYATDARVRAALSQETSDRTVVIVAQRVSTIRDADRILVLDAGRVVGSGTHTELMADNDVYREIVLSQLTEEEAA
>CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein
MEVLRRVFGYDSFRDGQREIVEHVVDGGDALVLMPTGGGKSLCYQIPALVRDGVGVVVSPLIALMQDQVDALTALGVRAGFLNSTQEPEERERVEEAFVDGRIDVLYLAPERLRLESTVRLLDRGTISLFAIDEAHCVAQWGHDFRPDYLLLSHLHQRWPDVPRIALTATATEATRAEIVSRLDLGGARQFVASSPTCTSGGRRCPGSR
>CP025990.1|AUS80434.1|4985698_4985878_+|hypothetical-protein
MTPAATVDGPTGKTRDDAEVRPPPWVWDVVGPAHAPTERCRHQPPVESGARTSAPAFRR
>CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein
MSTTRTTTATGTSERIRDADEVKALAEVLVTAATRAPSPHNTQPWRFEARGDGIALHLDRTRLLGVADPDGREARLACGAALFNLRLEARARGIAAATELLPDRNVPDLLGVVRLAGTHRPTGEERTLASAIPRRHTNRRPFAEEQPPEPLRHGLRRAAQLESGLLDFLDEPTRFADLARLIRSAEAAQRDDDAFMAELRCWTTGVASVRDGVPARSSGPPPLEEGLVTLRRYGRGRRPPRPYEQVPLLGVVLTNEDDQHAQLVGGHVMQRVLLAATAAGLSTSFVSQPMEVPSVKRELDRLVGSQGHPQTVLRIGYGYPALPTPRRPAREVTTGLPPVAEPG

Crispr_ID: CP025990_34

• CRISPR_ID: CP025990_34
• CRISPR_location: 4978696-4978788
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP025990_34

Consensus_repeat	Method
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CRISPRCasFinder

spacers of CP025990_34

>34.1|4978725|34|CP025990|CRISPRCasFinder
TCGGCCACGACAGCGATCAGGCCGACATCGTCGG

CRISPR arrays and Neighbor proteins around CP025990_34

CRISPR arrays

The CRISPR arrays of CP025990_34

>merge|CP025990|34|4978696-4978788|CRISPRCasFinder
CGGCTCACCCCCGCTCGCGCGGGGCCTTCTCGGCCACGACAGCGATCAGGCCGACATCGTCGGGCTCAACCCCCCGCTCGCGCGGGGCTTTCC

>CP025990|34|33|4978696-4978788|CRISPRCasFinder
CGGCTCACCCCCGCTCGCGCGGGGCCTTC	TCGGCCACGACAGCGATCAGGCCGACATCGTCGG
GCTCAACCCCCCGCTCGCGCGGGGCTTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80436.1|4987281_4987707_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein	unknown	unknown	gnl|CDD|236122
CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
CP025990.1|AUS80438.1|4991177_4991384_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS81919.1|4990457_4990685_-|hypothetical-protein	unknown	unknown	gnl|CDD|236040
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	unknown	unknown	gnl|CDD|224759
CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80434.1|4985698_4985878_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	unknown	unknown	gnl|CDD|214834
CP025990.1|AUS80437.1|4989817_4990021_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein	unknown	unknown	gnl|CDD|350678

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	7.84843e-15
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	5.47817e-12
CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein	gnl|CDD|236122	PRK07877, PRK07877, Rv1355c family protein.	4.41801e-22
CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.7686e-13
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	6.12669e-15
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	5.29271e-07
CP025990.1|AUS81919.1|4990457_4990685_-|hypothetical-protein	gnl|CDD|236040	PRK07523, PRK07523, gluconate 5-dehydrogenase; Provisional.	3.55485e-14
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.73014e-09
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	0.00135798
CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.38464e-163
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.82967e-17
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.25775e-05
CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein	gnl|CDD|214834	smart00823, PKS_PP, Phosphopantetheine attachment site. Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.	6.72887e-21
CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein	gnl|CDD|350678	cd17920, DEXHc_RecQ, DEXH-box helicase domain of RecQ family proteins. The RecQ family of the type II DEAD box helicase superfamily is a family of highly conserved DNA repair helicases. This domain contains the ATP-binding region.	3.09549e-104

Protein sequences

>CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein
MNHAEWRVLVTAHIVRNAHSQTASCIVSVDPANLVALTLVQSTVGLASSHARLLASLLTTPRSGTVTTLCANEDLVSQLTVTPGATLTHPARRPTGLIALDTLDTAHPVALLLEPEAATTMARALRTAASRLEGRVGAR
>CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator
MASKAQARALGAELRECRKQARVTMAEVARLIGCSTATMSLTETGKRLPPVEDVAAILAVLSVTGAKRERLVRMAREAAVEPRWLGVGIPGLAPQVTGMAELERTSVRITAVAPNLVPGLLQTANYARAVFAGSDVNPSEIEARTTFRMGRQRALDEVTYVALVDESVLRRPVGGARVIRDQLEHLVEMAGRPNITIQVLPMSLGWHDALEGPFVILEGEKTAPVVHLEHKRSGLFLDEDDADEVQTYMRSAANLQQRALTARQSVELIAAVHDDWSTNAGAAATEVANV
>CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein
MQAQQQPRWRTSSHSGSQSDCVEVACEPDVVSIRDTKNRDGGTLVVDRAAFGAFVKAVKTERL
>CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein
MQVDGEFGRWRKASRSGPQVECVEVGSNADHVAIRDTKNRGGGTLVVDHPTFGAFLTAVKDKRF
>CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein
MAEATGVGLADLSEKTADLVAVGYVVWSGEPGNRVLRMTPAGRMVALDLLPAVEAFLAELSGVSSTP
>CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein
MVLLSACASAEQGTAVAVGPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPETARFDDVGLSYDCVYRLAHEARPLMAIHLNWMRSVDQLSLTNYTVEEIGVGPLRALRIIGKTASEHCQISVDLSEQAHVSVYVHYAGTVEHACALAEETAGAVEPLLPRSSG
>CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVELTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEVTALGFDPESASFNDVGVSYSCNYRPPAGGTPLMYIGLDWKLSIDQLNLSNFIAEETSVGPLRALRITDKIDPESCQISLALSEQAHVSIFVKFGGTTEQACAIAEETAAAVEPSLPRSPG
>CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEMTALGFDPETATFDDVGLSHDCRYRFPGGERPVMTIHLNWMRGVDQLNLTNYTVEEIGVGPLRALRIIDEIPSEHCQISVDLSEQAHVSFFVHYAGTVERACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein
MGLLSACASAEQGTAVAVGPTVGSSLSGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESASFDDVGLSYACSYRLPSGGLALMAIDLNWKRSVDQLDLTNYTSEETVNSVSTTRAAAASSSAGVGSSARSSAAAWMSP
>CP025990.1|AUS80423.1|4966692_4967232_+|hypothetical-protein
MAASGSDAAVVAMATDLAGLRAQAQAGILPPIWRSLVRIPTRRAAGRQEGTAAGWGARLAALSVEERQREILSLVRSKVSVVLGHDDVAAVQARRSFKDLGFDSLTAVELRNTLTAATGLRTTPNTKNRVDPTSNHRRSVMCRSSPRSRCSPPPKRWARPLVDHGVIGRTDPGGQPPDR
>CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein
MASLPIEQVRRAVAEYFRTGRRPDCVQRQPGDWY
>CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein
MSARTTTEARPAPASAGRPPNEKSSDFLGSGRRVLGLLARERVAMVVVLVLALASVGLSVAGPRILGYATDLVVEGTFGPAAAGIDFGALGTVLLWVLGVYLASAVFGIVQGRLTNGAVQRTAGRLRRDAQAKLARLPLRHFNGQSRGEVLSRVTNDIDNVAQSLQQVLSQVIVSLLTLVAVLAMMFSISWLLALIALVSIPAAVLVTALIGKRAQPEFAEQWKSTGELNGHVEEMYTGHALVRAFGRQREAAEVFAERNERLFRSSFRAQFISGLIQPSMMFVSNLNYVLVAVVGGLRVTSGQLTIGDVQAFVQYSRQFTQPLTQVASMANLVQSGVASAERVFDFLDAEEEEPDPAEPRRVPTVRGRVEFEHVSFRYDPDKPLIEDLSLVAEPGQTIAIVGPTGAGKSTLVNLLMRFYEVTGGRITLDGVDTAEMTRADVRATTGMVLQDTWLFGGTIAENIAYGAKDATREQVVAAAKTAHVDHFARTLPEGYDTVVDEEGGGVSAGEKQLITIARAFLANPSILVLDEATSSVDTRTEVLIQRAMAELRSGRTAFVIAHRLSTIRDADRIVVMEEGAIVEQGTHDELLASGRPPLPHRSFDTIRA
>CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein
MLIALLRVHLRPYTGRLGLLVLLQLVQTVATLYLPTLNADIIDNGVIPGDQGRILTVGAVMIGATMLQVACAAGAVYLGAHTAMSVGRDIRAAVFHRTQSFSNRELGEFGAPSLITRTTNDVQQVQMLVLMTCTLMVTAPIMCVGGIVLALNQDVPLSGLLLALVPALGLVVVTLASRLRPLFRTMQERIDGVNRVLREQINGLQVIRAFGRDDHERERFRTANTALTDTALRIGRLMAVMFPLVMFVVNVATVAVTWIGAGRIDSGAMQVGALVAFLSYLMQILMAVMMATFMFMMVPRAEVCADRIQEVLTTTGTVRPPAHPVRELPGTGGLELRDVEFRYPGAEDPVLREVSFLARPGQTTAVIGSTGSGKSTLLSLVPRLADVTAGAVLVDGTDVRDLDPALLARTVSVVPQRPYLFSGTIASNLRYGNPDATDEELWRALEIAQAADFVRSRPEGLEAPVSQGGTNVSGGQRQRLAIARAVVQRPAVYLFDDSFSALDYATDARVRAALSQETSDRTVVIVAQRVSTIRDADRILVLDAGRVVGSGTHTELMADNDVYREIVLSQLTEEEAA
>CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein
MEVLRRVFGYDSFRDGQREIVEHVVDGGDALVLMPTGGGKSLCYQIPALVRDGVGVVVSPLIALMQDQVDALTALGVRAGFLNSTQEPEERERVEEAFVDGRIDVLYLAPERLRLESTVRLLDRGTISLFAIDEAHCVAQWGHDFRPDYLLLSHLHQRWPDVPRIALTATATEATRAEIVSRLDLGGARQFVASSPTCTSGGRRCPGSR
>CP025990.1|AUS80434.1|4985698_4985878_+|hypothetical-protein
MTPAATVDGPTGKTRDDAEVRPPPWVWDVVGPAHAPTERCRHQPPVESGARTSAPAFRR
>CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein
MSTTRTTTATGTSERIRDADEVKALAEVLVTAATRAPSPHNTQPWRFEARGDGIALHLDRTRLLGVADPDGREARLACGAALFNLRLEARARGIAAATELLPDRNVPDLLGVVRLAGTHRPTGEERTLASAIPRRHTNRRPFAEEQPPEPLRHGLRRAAQLESGLLDFLDEPTRFADLARLIRSAEAAQRDDDAFMAELRCWTTGVASVRDGVPARSSGPPPLEEGLVTLRRYGRGRRPPRPYEQVPLLGVVLTNEDDQHAQLVGGHVMQRVLLAATAAGLSTSFVSQPMEVPSVKRELDRLVGSQGHPQTVLRIGYGYPALPTPRRPAREVTTGLPPVAEPG
>CP025990.1|AUS80436.1|4987281_4987707_+|hypothetical-protein
MRSPIVGRLYGHVDLDTGHGPLVAPGLRYLVGTFDHRRTVLCGAVVRHYAEFDDLSTHTIAEMRDLARRWRVRDFVPPPTTLKRRRRRVPAWARVRLWSWEPEVELDVSYVGRVSFKHADWARIGSHPAGTPGGDAMCAHS
>CP025990.1|AUS80437.1|4989817_4990021_-|hypothetical-protein
MHLKESVVVDLPATAVEVTDAVDRRRVLDDILDQLSRPDNPQGLSEELDRAGWQARSPLLEITGLTG
>CP025990.1|AUS81919.1|4990457_4990685_-|hypothetical-protein
MRLDLTGRTALVTGSTQGIGAAIAVGLAQAGARVAVNGRRPGTVAEAADRVRTEVPGADVVPAPADVTAPSNTSW
>CP025990.1|AUS80438.1|4991177_4991384_+|hypothetical-protein
MIDHVVRTYPSAEPLPKEEQLAWKLAAVATDPVAVEPEVTEMVRTHGFGASQGSPSRRQLFASPPARN

Crispr_ID: CP025990_35

• CRISPR_ID: CP025990_35
• CRISPR_location: 4978992-4979264
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP025990_35

Consensus_repeat	Method
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CRISPRCasFinder
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CRT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	PILER-CR

spacers of CP025990_35

>35.1|4979021|32|CP025990|CRISPRCasFinder,CRT
CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
>35.2|4979082|32|CP025990|CRISPRCasFinder,CRT,PILER-CR
CCGTTCCCGGCCGGTGATCAGCATGACGGTCA
>35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR
TGGAGCTTCGAGGAAACCGCCGCCGCAATCGG
>35.4|4979204|32|CP025990|CRISPRCasFinder,CRT
GCCCGTGCCGGTGGCGGTGTGGCCGGTGTGGT

CRISPR arrays and Neighbor proteins around CP025990_35

CRISPR arrays

The CRISPR arrays of CP025990_35

>merge|CP025990|35|4978992-4979264|CRISPRCasFinder,CRT,PILER-CR
CAGCGGAACGGACCTCGCGCGGGGCAGACCGGATGTCCGCGACGGCGGCCTCGCGGGATGTCGGCTCACCCCCGCTCGCGCGGGGCAGACCCGTTCCCGGCCGGTGATCAGCATGACGGTCACGGCTCACCCCCGCTCGCGCGGGGCAGACTGGAGCTTCGAGGAAACCGCCGCCGCAATCGGCGGCTCACCCCCGCTCGCGCGGGGCAGACGCCCGTGCCGGTGGCGGTGTGGCCGGTGTGGTCGGCTCACCCCCGCTCGCGCGGGGCAGAC

>CP025990|35|34|4978992-4979264|CRISPRCasFinder
CAGCGGAACGGACCTCGCGCGGGGCAGAC	CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CCGTTCCCGGCCGGTGATCAGCATGACGGTCA
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	TGGAGCTTCGAGGAAACCGCCGCCGCAATCGG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GCCCGTGCCGGTGGCGGTGTGGCCGGTGTGGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC

>CP025990|35|27|4978992-4979264|CRT
CAGCGGAACGGACCTCGCGCGGGGCAGAC	CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CCGTTCCCGGCCGGTGATCAGCATGACGGTCA
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	TGGAGCTTCGAGGAAACCGCCGCCGCAATCGG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GCCCGTGCCGGTGGCGGTGTGGCCGGTGTGGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC

>CP025990|35|27|4979053-4979203|PILER-CR
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CCGTTCCCGGCCGGTGATCAGCATGACGGTCA
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	TGGAGCTTCGAGGAAACCGCCGCCGCAATCGG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80436.1|4987281_4987707_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein	unknown	unknown	gnl|CDD|236122
CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
CP025990.1|AUS80439.1|4991292_4991697_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP025990.1|AUS80438.1|4991177_4991384_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS81919.1|4990457_4990685_-|hypothetical-protein	unknown	unknown	gnl|CDD|236040
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	unknown	unknown	gnl|CDD|224759
CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80434.1|4985698_4985878_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	unknown	unknown	gnl|CDD|373064
CP025990.1|AUS80437.1|4989817_4990021_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein	unknown	unknown	gnl|CDD|350678

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	7.84843e-15
CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	5.47817e-12
CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein	gnl|CDD|236122	PRK07877, PRK07877, Rv1355c family protein.	4.41801e-22
CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
CP025990.1|AUS80439.1|4991292_4991697_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.90858e-07
CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	3.7686e-13
CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	6.12669e-15
CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.25775e-05
CP025990.1|AUS81919.1|4990457_4990685_-|hypothetical-protein	gnl|CDD|236040	PRK07523, PRK07523, gluconate 5-dehydrogenase; Provisional.	3.55485e-14
CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.73014e-09
CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	0.00135798
CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.38464e-163
CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.82967e-17
CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	5.29271e-07
CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein	gnl|CDD|350678	cd17920, DEXHc_RecQ, DEXH-box helicase domain of RecQ family proteins. The RecQ family of the type II DEAD box helicase superfamily is a family of highly conserved DNA repair helicases. This domain contains the ATP-binding region.	3.09549e-104

Protein sequences

>CP025990.1|AUS81918.1|4978874_4978979_-|hypothetical-protein
MASLPIEQVRRAVAEYFRTGRRPDCVQRQPGDWY
>CP025990.1|AUS80430.1|4978010_4978430_+|hypothetical-protein
MNHAEWRVLVTAHIVRNAHSQTASCIVSVDPANLVALTLVQSTVGLASSHARLLASLLTTPRSGTVTTLCANEDLVSQLTVTPGATLTHPARRPTGLIALDTLDTAHPVALLLEPEAATTMARALRTAASRLEGRVGAR
>CP025990.1|AUS80429.1|4975998_4976871_-|XRE-family-transcriptional-regulator
MASKAQARALGAELRECRKQARVTMAEVARLIGCSTATMSLTETGKRLPPVEDVAAILAVLSVTGAKRERLVRMAREAAVEPRWLGVGIPGLAPQVTGMAELERTSVRITAVAPNLVPGLLQTANYARAVFAGSDVNPSEIEARTTFRMGRQRALDEVTYVALVDESVLRRPVGGARVIRDQLEHLVEMAGRPNITIQVLPMSLGWHDALEGPFVILEGEKTAPVVHLEHKRSGLFLDEDDADEVQTYMRSAANLQQRALTARQSVELIAAVHDDWSTNAGAAATEVANV
>CP025990.1|AUS80428.1|4975844_4976036_-|DUF397-domain-containing-protein
MQAQQQPRWRTSSHSGSQSDCVEVACEPDVVSIRDTKNRDGGTLVVDRAAFGAFVKAVKTERL
>CP025990.1|AUS80427.1|4975296_4975491_-|DUF397-domain-containing-protein
MQVDGEFGRWRKASRSGPQVECVEVGSNADHVAIRDTKNRGGGTLVVDHPTFGAFLTAVKDKRF
>CP025990.1|AUS80426.1|4973464_4973668_+|hypothetical-protein
MAEATGVGLADLSEKTADLVAVGYVVWSGEPGNRVLRMTPAGRMVALDLLPAVEAFLAELSGVSSTP
>CP025990.1|AUS81917.1|4972412_4972967_-|DUF3558-domain-containing-protein
MVLLSACASAEQGTAVAVGPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPETARFDDVGLSYDCVYRLAHEARPLMAIHLNWMRSVDQLSLTNYTVEEIGVGPLRALRIIGKTASEHCQISVDLSEQAHVSVYVHYAGTVEHACALAEETAGAVEPLLPRSSG
>CP025990.1|AUS80425.1|4971514_4972069_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVELTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEVTALGFDPESASFNDVGVSYSCNYRPPAGGTPLMYIGLDWKLSIDQLNLSNFIAEETSVGPLRALRITDKIDPESCQISLALSEQAHVSIFVKFGGTTEQACAIAEETAAAVEPSLPRSPG
>CP025990.1|AUS81916.1|4970616_4971171_-|DUF3558-domain-containing-protein
MGLLSACTSAERGTAVAVEPTVGSSLPGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEMTALGFDPETATFDDVGLSHDCRYRFPGGERPVMTIHLNWMRGVDQLNLTNYTVEEIGVGPLRALRIIDEIPSEHCQISVDLSEQAHVSFFVHYAGTVERACALAEDTAAAVEPLLPRSSG
>CP025990.1|AUS80424.1|4969814_4970273_-|DUF3558-domain-containing-protein
MGLLSACASAEQGTAVAVGPTVGSSLSGSADPSVGGSPGEQPGVDVAAELSEMLPCEILSDEEITALGFDPESASFDDVGLSYACSYRLPSGGLALMAIDLNWKRSVDQLDLTNYTSEETVNSVSTTRAAAASSSAGVGSSARSSAAAWMSP
>CP025990.1|AUS80431.1|4980236_4982066_-|ABC-transporter-ATP-binding-protein
MSARTTTEARPAPASAGRPPNEKSSDFLGSGRRVLGLLARERVAMVVVLVLALASVGLSVAGPRILGYATDLVVEGTFGPAAAGIDFGALGTVLLWVLGVYLASAVFGIVQGRLTNGAVQRTAGRLRRDAQAKLARLPLRHFNGQSRGEVLSRVTNDIDNVAQSLQQVLSQVIVSLLTLVAVLAMMFSISWLLALIALVSIPAAVLVTALIGKRAQPEFAEQWKSTGELNGHVEEMYTGHALVRAFGRQREAAEVFAERNERLFRSSFRAQFISGLIQPSMMFVSNLNYVLVAVVGGLRVTSGQLTIGDVQAFVQYSRQFTQPLTQVASMANLVQSGVASAERVFDFLDAEEEEPDPAEPRRVPTVRGRVEFEHVSFRYDPDKPLIEDLSLVAEPGQTIAIVGPTGAGKSTLVNLLMRFYEVTGGRITLDGVDTAEMTRADVRATTGMVLQDTWLFGGTIAENIAYGAKDATREQVVAAAKTAHVDHFARTLPEGYDTVVDEEGGGVSAGEKQLITIARAFLANPSILVLDEATSSVDTRTEVLIQRAMAELRSGRTAFVIAHRLSTIRDADRIVVMEEGAIVEQGTHDELLASGRPPLPHRSFDTIRA
>CP025990.1|AUS80432.1|4982062_4983796_-|ABC-transporter-ATP-binding-protein
MLIALLRVHLRPYTGRLGLLVLLQLVQTVATLYLPTLNADIIDNGVIPGDQGRILTVGAVMIGATMLQVACAAGAVYLGAHTAMSVGRDIRAAVFHRTQSFSNRELGEFGAPSLITRTTNDVQQVQMLVLMTCTLMVTAPIMCVGGIVLALNQDVPLSGLLLALVPALGLVVVTLASRLRPLFRTMQERIDGVNRVLREQINGLQVIRAFGRDDHERERFRTANTALTDTALRIGRLMAVMFPLVMFVVNVATVAVTWIGAGRIDSGAMQVGALVAFLSYLMQILMAVMMATFMFMMVPRAEVCADRIQEVLTTTGTVRPPAHPVRELPGTGGLELRDVEFRYPGAEDPVLREVSFLARPGQTTAVIGSTGSGKSTLLSLVPRLADVTAGAVLVDGTDVRDLDPALLARTVSVVPQRPYLFSGTIASNLRYGNPDATDEELWRALEIAQAADFVRSRPEGLEAPVSQGGTNVSGGQRQRLAIARAVVQRPAVYLFDDSFSALDYATDARVRAALSQETSDRTVVIVAQRVSTIRDADRILVLDAGRVVGSGTHTELMADNDVYREIVLSQLTEEEAA
>CP025990.1|AUS80433.1|4984951_4985581_-|hypothetical-protein
MEVLRRVFGYDSFRDGQREIVEHVVDGGDALVLMPTGGGKSLCYQIPALVRDGVGVVVSPLIALMQDQVDALTALGVRAGFLNSTQEPEERERVEEAFVDGRIDVLYLAPERLRLESTVRLLDRGTISLFAIDEAHCVAQWGHDFRPDYLLLSHLHQRWPDVPRIALTATATEATRAEIVSRLDLGGARQFVASSPTCTSGGRRCPGSR
>CP025990.1|AUS80434.1|4985698_4985878_+|hypothetical-protein
MTPAATVDGPTGKTRDDAEVRPPPWVWDVVGPAHAPTERCRHQPPVESGARTSAPAFRR
>CP025990.1|AUS80435.1|4986061_4987093_+|hypothetical-protein
MSTTRTTTATGTSERIRDADEVKALAEVLVTAATRAPSPHNTQPWRFEARGDGIALHLDRTRLLGVADPDGREARLACGAALFNLRLEARARGIAAATELLPDRNVPDLLGVVRLAGTHRPTGEERTLASAIPRRHTNRRPFAEEQPPEPLRHGLRRAAQLESGLLDFLDEPTRFADLARLIRSAEAAQRDDDAFMAELRCWTTGVASVRDGVPARSSGPPPLEEGLVTLRRYGRGRRPPRPYEQVPLLGVVLTNEDDQHAQLVGGHVMQRVLLAATAAGLSTSFVSQPMEVPSVKRELDRLVGSQGHPQTVLRIGYGYPALPTPRRPAREVTTGLPPVAEPG
>CP025990.1|AUS80436.1|4987281_4987707_+|hypothetical-protein
MRSPIVGRLYGHVDLDTGHGPLVAPGLRYLVGTFDHRRTVLCGAVVRHYAEFDDLSTHTIAEMRDLARRWRVRDFVPPPTTLKRRRRRVPAWARVRLWSWEPEVELDVSYVGRVSFKHADWARIGSHPAGTPGGDAMCAHS
>CP025990.1|AUS80437.1|4989817_4990021_-|hypothetical-protein
MHLKESVVVDLPATAVEVTDAVDRRRVLDDILDQLSRPDNPQGLSEELDRAGWQARSPLLEITGLTG
>CP025990.1|AUS81919.1|4990457_4990685_-|hypothetical-protein
MRLDLTGRTALVTGSTQGIGAAIAVGLAQAGARVAVNGRRPGTVAEAADRVRTEVPGADVVPAPADVTAPSNTSW
>CP025990.1|AUS80438.1|4991177_4991384_+|hypothetical-protein
MIDHVVRTYPSAEPLPKEEQLAWKLAAVATDPVAVEPEVTEMVRTHGFGASQGSPSRRQLFASPPARN
>CP025990.1|AUS80439.1|4991292_4991697_-|hypothetical-protein
MVRRTRSSLRSPRARAVGQAIRQAREDAGIGVRELARRLSVGHAWVGRVERAEVLLTPDLVAAIAGALELAPADRESLVDQTRNLAAGSPWTPSSDLPGQLATLISYEQEAMRIADVATVIPGLLQTRAYAPSR

Crispr_ID: CP025990_36

• CRISPR_ID: CP025990_36
• CRISPR_location: 5001117-5001572
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of CP025990_36

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT

spacers of CP025990_36

>36.1|5001145|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGGCGCTACAGCGGCCGGCCCAACTTCGAGTTG
>36.2|5001206|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CACGTCCACCGCGCCCGAGTTCGACAGGGGGCC
>36.3|5001267|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGGGTCATCACCCAACGGGGCACGAATGGCCAG
>36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCAGTACCTCTACTACTCGTCCCTCGGCCTCGTC
>36.5|5001390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCGATGAGGCGGTGCTTCGACAGGAGCGCAGCC
>36.6|5001451|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GACGGCGTGAACCCGCGCCACCGGTGCCTCTTG
>36.7|5001512|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CACCGGGACCCATGTTGACCAGCGCAAACGATG

CRISPR arrays and Neighbor proteins around CP025990_36

CRISPR arrays

The CRISPR arrays of CP025990_36

>merge|CP025990|36|5001117-5001572|PILER-CR,CRISPRCasFinder,CRT
GGAACAGCCCCGCGTGCGCGGGGAGGACGGGCGCTACAGCGGCCGGCCCAACTTCGAGTTGGGAACAGCCCCGCGTGCGCGGGGAGGACCACGTCCACCGCGCCCGAGTTCGACAGGGGGCCGGAACAGCCCCGCGTGCGCGGGGAGGACTGGGTCATCACCCAACGGGGCACGAATGGCCAGGGAACAGCCCCGCGTGCGCGGGGAGGACCCAGTACCTCTACTACTCGTCCCTCGGCCTCGTCGGAACAGCCCCGCGTGCGCGGGGAGGACTCGATGAGGCGGTGCTTCGACAGGAGCGCAGCCGGAACAGCCCCGCGTGCGCGGGGAGGACGACGGCGTGAACCCGCGCCACCGGTGCCTCTTGGGAACAGCCCCGCGTGCGCGGGGAGGACCACCGGGACCCATGTTGACCAGCGCAAACGATGGGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|36|28|5001117-5001572|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GGGCGCTACAGCGGCCGGCCCAACTTCGAGTTG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CACGTCCACCGCGCCCGAGTTCGACAGGGGGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TGGGTCATCACCCAACGGGGCACGAATGGCCAG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCAGTACCTCTACTACTCGTCCCTCGGCCTCGTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCGATGAGGCGGTGCTTCGACAGGAGCGCAGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GACGGCGTGAACCCGCGCCACCGGTGCCTCTTG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CACCGGGACCCATGTTGACCAGCGCAAACGATG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|36|35|5001117-5001572|CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GGGCGCTACAGCGGCCGGCCCAACTTCGAGTTG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CACGTCCACCGCGCCCGAGTTCGACAGGGGGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TGGGTCATCACCCAACGGGGCACGAATGGCCAG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCAGTACCTCTACTACTCGTCCCTCGGCCTCGTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCGATGAGGCGGTGCTTCGACAGGAGCGCAGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GACGGCGTGAACCCGCGCCACCGGTGCCTCTTG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CACCGGGACCCATGTTGACCAGCGCAAACGATG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|36|28|5001117-5001572|CRT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GGGCGCTACAGCGGCCGGCCCAACTTCGAGTTG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CACGTCCACCGCGCCCGAGTTCGACAGGGGGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TGGGTCATCACCCAACGGGGCACGAATGGCCAG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CCAGTACCTCTACTACTCGTCCCTCGGCCTCGTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCGATGAGGCGGTGCTTCGACAGGAGCGCAGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GACGGCGTGAACCCGCGCCACCGGTGCCTCTTG
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CACCGGGACCCATGTTGACCAGCGCAAACGATG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81921.1|5004400_5004592_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80444.1|4997274_4998285_-|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl|CDD|223101
CP025990.1|AUS81922.1|5005067_5005745_-|hypothetical-protein	unknown	unknown	gnl|CDD|319844
CP025990.1|AUS80451.1|5008855_5011219_-|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl|CDD|237060
CP025990.1|AUS80450.1|5008222_5008783_-|N-acetyltransferase	unknown	unknown	gnl|CDD|366181
CP025990.1|AUS80454.1|5013687_5014311_-|amino-acid-transporter	unknown	unknown	unknown
CP025990.1|AUS80440.1|4993127_4993424_+|hypothetical-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS80448.1|5006183_5006438_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80449.1|5006753_5008100_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
CP025990.1|AUS80439.1|4991292_4991697_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP025990.1|AUS80442.1|4994615_4995425_-|FAD-binding-molybdopterin-dehydrogenase	unknown	unknown	gnl|CDD|224238
CP025990.1|AUS80438.1|4991177_4991384_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80446.1|4999522_5000161_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379522
CP025990.1|AUS80447.1|5000706_5001006_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80445.1|4998281_4999385_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl|CDD|274473
CP025990.1|AUS80452.1|5011636_5012170_+|N-acetyltransferase	unknown	unknown	gnl|CDD|379112
CP025990.1|AUS80443.1|4995985_4997278_-|dihydrolipoamide-acetyltransferase	unknown	unknown	gnl|CDD|237001
CP025990.1|AUS80441.1|4993686_4994049_-|hypothetical-protein	unknown	unknown	gnl|CDD|377110
CP025990.1|AUS80453.1|5012372_5013497_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81920.1|5003539_5004391_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379262

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81921.1|5004400_5004592_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.62847e-17
CP025990.1|AUS80444.1|4997274_4998285_-|alpha-ketoacid-dehydrogenase-subunit-beta	gnl|CDD|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	5.57549e-164
CP025990.1|AUS81922.1|5005067_5005745_-|hypothetical-protein	gnl|CDD|319844	cd07544, P-type_ATPase_HM, P-type heavy metal-transporting ATPase; uncharacterized subfamily. Uncharacterized subfamily of the heavy metal-transporting ATPases (Type IB ATPases) which transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	5.08415e-38
CP025990.1|AUS80451.1|5008855_5011219_-|accessory-Sec-system-translocase-SecA2	gnl|CDD|237060	PRK12326, PRK12326, preprotein translocase subunit SecA; Reviewed.	0
CP025990.1|AUS80450.1|5008222_5008783_-|N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.2669e-08
CP025990.1|AUS80440.1|4993127_4993424_+|hypothetical-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	1.03939e-06
CP025990.1|AUS80449.1|5006753_5008100_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.90356e-70
CP025990.1|AUS80439.1|4991292_4991697_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.90858e-07
CP025990.1|AUS80442.1|4994615_4995425_-|FAD-binding-molybdopterin-dehydrogenase	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	8.90771e-19
CP025990.1|AUS80446.1|4999522_5000161_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379522	pfam14246, TetR_C_7, AefR-like transcriptional repressor, C-terminal region. This family comprises the C-terminal domain of transcriptional regulators of the TetR family. It includes the AefR transcriptional regulator from P. syringae. It is found in association with pfam00440.	8.61718e-20
CP025990.1|AUS80445.1|4998281_4999385_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl|CDD|274473	TIGR03182, Pyruvate_dehydrogenase_E1_component_subunit_alpha, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	3.1539e-155
CP025990.1|AUS80452.1|5011636_5012170_+|N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.78597e-13
CP025990.1|AUS80443.1|4995985_4997278_-|dihydrolipoamide-acetyltransferase	gnl|CDD|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	4.57603e-153
CP025990.1|AUS80441.1|4993686_4994049_-|hypothetical-protein	gnl|CDD|377110	pfam03720, UDPG_MGDP_dh_C, UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain. The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.	2.36661e-25
CP025990.1|AUS81920.1|5003539_5004391_+|XRE-family-transcriptional-regulator	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	4.88236e-06

Protein sequences

>CP025990.1|AUS80447.1|5000706_5001006_-|hypothetical-protein
MGVQRASQTVPDLVIAAGTGASWGITGRAAPSSCAFVERVGEFDRQLRHRHVRRSSDREHGVLNLDSTPYGLLTRGGTRMGPDARSAVPDDGSSGSVVG
>CP025990.1|AUS80446.1|4999522_5000161_+|TetR/AcrR-family-transcriptional-regulator
MTHVEATGRPKRGRPTQEERERRRDQVLDAAVSLFVAKGFGQTSIDELAAAARVTKRTIYTYFGDKAEVFTAAVERFRVSALAQLTAEDESLTDVATRLVLVLHSDEAVGLHRLMIAEAPQFPRLAERFYASGPLGYIELLSALLDAEGTPPDAAADGRAEALFGLLLGEPHRRRLLGLTAAPSPAEARRHARAALRLVVGEVTAPADRPTS
>CP025990.1|AUS80445.1|4998281_4999385_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MAKRRPTVREPRGQHGPAGEDAATDGGQRREFYRRMVFIRRFEERAARAYTQAEIGGYCHLNLGEEATVVGLMSALEQTDYLFTNYREHGYALARGVAAGRVMAELYGRRDGVSKGWGGSMHLFDGNARLLGGYGIVGGQLPLATGAALAIDYRGGDEAVACVMGDGTTNIGAFHESLNIAALWNLPVVYVVVNNGLGMGTTVEKASGEPELHRKAASYRMSSARVDGNDPVAVREAMLSALASARSGRPFLLEAVSSRLKGHSVVDPAKYRTREEVEALRTSDPVAALAFRLRDEGELTDEAIAEIDAEATSAVAAAVAFAEASPAPSVDTLFDYTYATPVPNDSRRLPGQPLFEPAPLPRIGADR
>CP025990.1|AUS80444.1|4997274_4998285_-|alpha-ketoacid-dehydrogenase-subunit-beta
MSIMTYRQALRDTLRTEMRRDPDVLLLGEEIGVFEGSYKITAGLLAEFGEKRVRDTPIAEEGFTGAAIGAAMLGLRPVVEIMTINFSLLALDQIVNHAAKIYGMFGGQARVPLVIRTPGGGGQQLGATHSQNIELYYAFVPGMKVVAPSNPADAKSLLLAAIRDDDPVLFLENLALYNAKGEVPDDDTPGEIGRAAVTRPGRDITVVAYSRMAAVALTVAERMAQTDGIDIEVVDLRSLRPLDRETVVDSVRRTHCAVVLEDDWLTYGIGAEIAATISDGAFDWLDAPVRRVAMAEVPLPYAKTLETAALPSADDVTTAIRQTLASVGRRAGKDIP
>CP025990.1|AUS80443.1|4995985_4997278_-|dihydrolipoamide-acetyltransferase
MIDILMPRLSDTMEEGVIVAWRKKPGEAVEIGDVLVEIETDKATMEHEAYEAGTLHEILLPEGETVRIGTVIARIDDGREPLAGTPPRDGTSQGKPPAPATSEPPIPESGPAPATDPAPTEGGAATSPPARRPLATPLVRRLARDNAIDLNEIIGSGPGGRIIRADLDRALARGPGATGHSVPAASGGATTPNGGVPTGATSVPFDTTRQVISRRLTESSSSVPHFSVTAVADVEELLALRARINAELDDAGQGKVSLNDLIVRASAVALREHPGVNASYSEEGRGATLLHEHVNIGIAVASDHGLVVPVIADADRMAVSRIAAESRRLVGLAKDRKLSGADMTGGTFTISNLGMYQVESFTAIINPPEGAILAVGAALPEPAAVEGAVAVRHRIRCTLSADHRIIDGALAARFLSTLTSLLEHPLRIIA
>CP025990.1|AUS80442.1|4994615_4995425_-|FAD-binding-molybdopterin-dehydrogenase
MDLNTVTEVRDARQRGEWRPGDAWLAGGTYLFSEPQPHLRRLVDLARMDWPPVAILADGSWEIAATCTIAELSAFAATTGPATSGLVERCCRAFLASVKIWNTATVGGNLCLALPAGPMISLTAALGAVCRLIATDGTRRALPVTDLITGPARTALTEGELLRSVTIPARALSARTAFRRASQHQHGRSSALLVGTLDGRRFSLTVTASTPRPVVLEFAAPPTAEALSTAIDGAVGGNWLDDVHGIPAWRRHLTLRLADEVLAELGAAP
>CP025990.1|AUS80441.1|4993686_4994049_-|hypothetical-protein
MLGVSFKNDTGDLRNTPVAGVVEALRAQGCAVRLFDPLADAEEVRARFGIRPTATLEDAVDGAHCVAVLAGHRPFHDLDLAVLRARAAHPCLVFDGRRYFPKADIEEMRRLGLRYRGIGR
>CP025990.1|AUS80440.1|4993127_4993424_+|hypothetical-protein
MYRDIGRTGLGEVYDRRDAYAVFTPITIEGYPAVAAQHVEQTRNCQVFVGTAHDQQFVVQSDNARYADDGVTEIERRDPCGRAADVARAVLVRLPTGD
>CP025990.1|AUS80439.1|4991292_4991697_-|hypothetical-protein
MVRRTRSSLRSPRARAVGQAIRQAREDAGIGVRELARRLSVGHAWVGRVERAEVLLTPDLVAAIAGALELAPADRESLVDQTRNLAAGSPWTPSSDLPGQLATLISYEQEAMRIADVATVIPGLLQTRAYAPSR
>CP025990.1|AUS80438.1|4991177_4991384_+|hypothetical-protein
MIDHVVRTYPSAEPLPKEEQLAWKLAAVATDPVAVEPEVTEMVRTHGFGASQGSPSRRQLFASPPARN
>CP025990.1|AUS81920.1|5003539_5004391_+|XRE-family-transcriptional-regulator
MSERSDPSALRWLIGVELANYRKQSGLSLAQVSQLSGITKPKLGNMEAGRFQQYPDDIATVLRVYGVAERDIDRLCALAGSSDRRAWWAPWSHVVPDWVQTFVGLEGLATSEFVYEPTIVPGILQVEDYAEELTRATGFVRSDHHERFVSFRLARAERLTRPKPLHVHAVVSESALTLRVGSRATRNAQYHHLLALAALPNVVIQVVRPEAGPHAAATGPFYLFNFELARPIGYVELLDGAVYVQDVDQIGTYRMAADSVVHAALSPTDTVDFIHSLISGNGD
>CP025990.1|AUS81921.1|5004400_5004592_+|DUF397-domain-containing-protein
MNAMDLTTACWRKSSHSANNGVCVEVAGGADWAAIRDSKNPDGGALLLDHAQYRSFIRSVKRG
>CP025990.1|AUS81922.1|5005067_5005745_-|hypothetical-protein
MVGTGRLLETLAQRRAGHDLSALLDRIPRTARLVTVDGPRPVPVAELGPGDRIVVAAGEVVPVDAGVTADASFDESALTGEPDPVTRRAGDTVRSGVVSVGQAVELVATASAEDSTYAGVVRLAEQAGSTASRRPGNLPSREPKPIRISTRASCWPRHWWIPWPKARWLVDRRVMSSRSGSGNRVGSQFAAGTETVTLSPARMSWPSSSMSSRAVRIGPTWITLR
>CP025990.1|AUS80448.1|5006183_5006438_+|hypothetical-protein
MTRSSDNGGGEAGHRVGAGEPGELGDQADPEAGGSAPGPRPRPGLSRGPILEDAFQILARPPLAVWALLQTDRENGIDGNSSTK
>CP025990.1|AUS80449.1|5006753_5008100_-|cytochrome-P450
MSGGVLQRSGTRHTVWRFRNRTVRYRPGDALLALRARRGPVTRLRVGSRDVAFLLGPEANRFVFANSHLFRWREAFQSLVPVDGPTALIVSDGAEHRRRRRLVAPAMHHRQVARYVTTMAASADEAVADWRPGQVVDVYATFRRAVLRSTLESLFGRRLAADTAFFGDHLEVLLRLLDPLPQLNGPRERLATPLWRRATAAREVVDERIRNEIARVRGGIVDSDDHVLAALVNGVDEEGTALSDAEIRDQAVSLIAAGYETTSAAMAWAVYAMLSTSGVWDRARAEVLAECGEEPPTAAALKRLTFLGGVVHETLRLYPPAVLSARTAAVDLTVAGQPVRAGTTILFSPYVTHRMPGVWAEPLRFRPERWDPASPVHERPTTATYLPFAAGPHRCVGSVFATTELTVMLARLLTRTSLRLVPQWIQPTSFAAMRPRWGLRAVVCPGRG
>CP025990.1|AUS80450.1|5008222_5008783_-|N-acetyltransferase
MLVREGTERDLPVLLTLFDGAVRWLTARGREAQWGSVPWSERPEAVDRLRGIATAGGLLIAETGGTPTGALSTREVPPEYVEPVEERELYVHLLITDRESAPRGLGRALLDHAVGQARDRGIDLVRVDCWAGGGGALVDYYRSTGFTPSHRFERNGWPGQVLTRRVSDEPAVTAPVGRGTADRAVP
>CP025990.1|AUS80451.1|5008855_5011219_-|accessory-Sec-system-translocase-SecA2
MGRLSSAFWKVLGGSRRRAFSRSRAVVATAAKLEGEYRELTESDLAERLAALSRRHRPVDGDDGAGSTATFDRDELVRFLALAREVSRRRLDMPAFDVQLLAAARMFAGDVVEMLTGEGKTLAGAIGATAFALRGRQVHVISVNDYLARRDAEWMAPLYEAFGLSVAWISSTSTPEEREAAYAADVTYAAVSEFGFDVLRDRLGTDPIVPAPQVALVDEADSVLVDEARVPLVLAGSTAGAAPDSIITDLVRALKPDLHYRTDEDDRNVFLTEKGAAAVEDALGGVDLYSEEHVGTTLSQVNVALHARVLLRRDVHYLVRDGRVQLINESRGRVAELQRWPDGLQAAVEAKEGLAVSDTGEVLDTMTVQALISRYPTVCGMTGTARAADEQLRTFYDLGVSIIPPNRPCVRVDEPSRVYATIADKEAAIVDYIARTHETGQPVLIGTMDVAESEHLAKLLERAGVDCVVLNAKNDAAEAAIIAEAGALGAVTVSTQMAGRGTDIRLGGSDQADHEKVKDLGGLCVVGTNRHVSRRLDEQLRGRAGRQGDPGRSIFFSSLEDDLVVRHAPDARLPTTTEEDGQVTGLAAERLLDHAQRVADAALLEIHSNTFRYSRLSERHRAILDERRELLLGTDTALRELERRCPDRYRELSAEIDEEVLVSVARRITLFHLDRCWVEHLAFLSDLRESIHLHALGKQNPLDEYHRAAIPAFRDLLGEVDERAARTFEEATITAEGIDLDDAGLVRPTATWTYLVQDNPFGSELDRAFRGIRRMLDGRRGRADDED
>CP025990.1|AUS80452.1|5011636_5012170_+|N-acetyltransferase
MGDVISSERLDLVPLDAEALSLVVVGDVPGLERALGVVVPPEWPATVPARLRLDQLAEDPAELPWLVRAMVDRDERRIVGVTGFHGRPDDRGRAEVGYEVLPGDRRRGYAREAVLALADWANASGAALTCVASVAPTNEESLSLVRSLGFRQVGERLDPVDGVELVFERGLPFSLDP
>CP025990.1|AUS80453.1|5012372_5013497_+|hypothetical-protein
MTTPFPPTSAPAGDPPFRVLSDPADLPAVPEEVPPTDAQAWCSFVVWVPDRLPTGCVARAGTLRREAPPGRPDGSDVGRSPWSRANPCAYRFEVVGEGRRLRVKQFLYDWAVPALDHPSLWRSRTSARPLDGRHVLWFGVDYLGNRGTSARLGRTMVELSVLDGEFTEEELLDLHRSLRPADADAPSRLAAVPFAELSYWARHHDVEMVVVPTGIWRFDRDGDTAHEGDWVTPPHHAALLGALGLPERLGGLAVDSAARFTNAEGRTEVEVLYSGGPDRGRELRLVAQRTGRGRLVVPPRPSAHEWATRTTTTLRGTTVWLGWIDEDHGPFDCVGRAANGVEFRLVSGSGVGLDRRWFESASTELLAGWDPPAR
>CP025990.1|AUS80454.1|5013687_5014311_-|amino-acid-transporter
MIAEDDLGRWDPLGVPEVAALLAEVAAPWWVAGGHAVELAVGRPVRAHSDVDVVVLRPDVAAFRLALADWELWAADPPGTLRRWEPGEPLPTRVHDIWCRPTASAPWRLQLMVDERVGGEWVSRRDPRVRRPVAGLGWRTATGVPVLAPEVQLYYKAAAPRHRDEIDFAAVLPRLDEGRRTWLRNHLGADHPWRTRLDDEGPSPRRG

Crispr_ID: CP025990_38

• CRISPR_ID: CP025990_38
• CRISPR_location: 5443903-5445338
• CRISPR_type: TypeI
• Repeat_type: NA:I-C,III-B
• Spacer_info: 19 spacers
• Cas_protein_info: cas2,cas1,cas4,cas7,cas8c,cas5,cas3

Consensus repeat of CP025990_38

Consensus_repeat	Method
GTTG-------CACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	PILER-CR
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CRISPRCasFinder
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CRT

spacers of CP025990_38

>38.1|5443940|39|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACCGGGCCCCCCCCGGTCAGGTCGAGGCGGACCAGGGGC
>38.2|5444016|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGCTCCAAGGACCCCGGAGAGTTGGGGAGAACGCTC
>38.3|5444089|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCGACGATCACGTCCGCCTCGCCGCGTCTGGGCGAGT
>38.4|5444163|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
TTCGACAACCAACCCATAGTGCTTCTCCTTCTCAG
>38.5|5444235|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCGGCGTTGAACGGCGGTCGCGGGACGCCAGCGATG
>38.6|5444309|38|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCCGGACGGATGTGCAGCATCCGCTCGGGGCTGATCCG
>38.7|5444384|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTGTCGCGGTACGACGGTGGCGAGGCAGACATCCT
>38.8|5444456|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
TACCTCCGCCAGCTGCTCACCCTGCCCGTGTGGCTGG
>38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGGGCCGGGGCGGCGGCGGTGGCGGTCCGGGGCGTC
>38.10|5444603|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCCACGCGCAGGCGTCGGCCGCGACCGCGCTGGCCCG
>38.11|5444677|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGGGACCTCGGCTCCCCCGGCCCTGGGTCCGGCGCGG
>38.12|5444751|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACATTCGCCGATGCTTGTTCCCGCCGACCGTCGGTC
>38.13|5444824|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGTTCTCAGGGCTACACGGAGGTGGTCGCGGGACAGC
>38.14|5444898|35|CP025990|PILER-CR,CRISPRCasFinder,CRT
CACCGCAAGGCAGTGGCGGCGGGCAACGCCGCCAT
>38.15|5444970|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGCGGCCACCGCCATGAGGGATTCGGCCGCGTGGCC
>38.16|5445043|39|CP025990|PILER-CR,CRISPRCasFinder,CRT
ATCGTGTCGGCACCCGAAACGGACCGGGAGTTTCTCCAA
>38.17|5445119|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
CACAGGGATAGGGCCACGTGCGGGACCTCCGAACAG
>38.18|5445192|37|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACCACGGACGTCGCGGAGATCAGGGACTGGCTGTCCG
>38.19|5445266|36|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGGCCTGTGCACGGTCTCGTGCGCACCCGTAGATC

CRISPR arrays and Neighbor proteins around CP025990_38

CRISPR arrays

The CRISPR arrays of CP025990_38

>merge|CP025990|38|5443903-5445338|PILER-CR,CRISPRCasFinder,CRT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACACCGGGCCCCCCCCGGTCAGGTCGAGGCGGACCAGGGGCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACCGCTCCAAGGACCCCGGAGAGTTGGGGAGAACGCTCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACGCGACGATCACGTCCGCCTCGCCGCGTCTGGGCGAGTGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACTTCGACAACCAACCCATAGTGCTTCTCCTTCTCAGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACGCCGGCGTTGAACGGCGGTCGCGGGACGCCAGCGATGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACTCCGGACGGATGTGCAGCATCCGCTCGGGGCTGATCCGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACGTGTCGCGGTACGACGGTGGCGAGGCAGACATCCTGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACTACCTCCGCCAGCTGCTCACCCTGCCCGTGTGGCTGGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACGGGGCCGGGGCGGCGGCGGTGGCGGTCCGGGGCGTCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACCCCACGCGCAGGCGTCGGCCGCGACCGCGCTGGCCCGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACTGGGACCTCGGCTCCCCCGGCCCTGGGTCCGGCGCGGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACACATTCGCCGATGCTTGTTCCCGCCGACCGTCGGTCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACCGTTCTCAGGGCTACACGGAGGTGGTCGCGGGACAGCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACCACCGCAAGGCAGTGGCGGCGGGCAACGCCGCCATGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACGGCGGCCACCGCCATGAGGGATTCGGCCGCGTGGCCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACATCGTGTCGGCACCCGAAACGGACCGGGAGTTTCTCCAAGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACCACAGGGATAGGGCCACGTGCGGGACCTCCGAACAGGTTGCACCGGGCCTCCGGGCTCGGTGAGGATCGCAACACCACGGACGTCGCGGAGATCAGGGACTGGCTGTCCGGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAACCGGGCCTGTGCACGGTCTCGTGCGCACCCGTAGATCGTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC

>CP025990|38|30|5443903-5445338|PILER-CR
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ACCGGGCCCCCCCCGGTCAGGTCGAGGCGGACCAGGGGC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGCTCCAAGGACCCCGGAGAGTTGGGGAGAACGCTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GCGACGATCACGTCCGCCTCGCCGCGTCTGGGCGAGT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TTCGACAACCAACCCATAGTGCTTCTCCTTCTCAG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GCCGGCGTTGAACGGCGGTCGCGGGACGCCAGCGATG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TCCGGACGGATGTGCAGCATCCGCTCGGGGCTGATCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GTGTCGCGGTACGACGGTGGCGAGGCAGACATCCT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TACCTCCGCCAGCTGCTCACCCTGCCCGTGTGGCTGG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GGGGCCGGGGCGGCGGCGGTGGCGGTCCGGGGCGTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CCCACGCGCAGGCGTCGGCCGCGACCGCGCTGGCCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TGGGACCTCGGCTCCCCCGGCCCTGGGTCCGGCGCGG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ACATTCGCCGATGCTTGTTCCCGCCGACCGTCGGTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGTTCTCAGGGCTACACGGAGGTGGTCGCGGGACAGC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CACCGCAAGGCAGTGGCGGCGGGCAACGCCGCCAT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GGCGGCCACCGCCATGAGGGATTCGGCCGCGTGGCC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ATCGTGTCGGCACCCGAAACGGACCGGGAGTTTCTCCAA
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CACAGGGATAGGGCCACGTGCGGGACCTCCGAACAG
GTTGCACCGGGCCTCCGGGCTCGGTGAGGATCGCAAC	ACCACGGACGTCGCGGAGATCAGGGACTGGCTGTCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGGGCCTGTGCACGGTCTCGTGCGCACCCGTAGATC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC

>CP025990|38|36|5443903-5445338|CRISPRCasFinder
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ACCGGGCCCCCCCCGGTCAGGTCGAGGCGGACCAGGGGC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGCTCCAAGGACCCCGGAGAGTTGGGGAGAACGCTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GCGACGATCACGTCCGCCTCGCCGCGTCTGGGCGAGT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TTCGACAACCAACCCATAGTGCTTCTCCTTCTCAG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GCCGGCGTTGAACGGCGGTCGCGGGACGCCAGCGATG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TCCGGACGGATGTGCAGCATCCGCTCGGGGCTGATCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GTGTCGCGGTACGACGGTGGCGAGGCAGACATCCT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TACCTCCGCCAGCTGCTCACCCTGCCCGTGTGGCTGG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GGGGCCGGGGCGGCGGCGGTGGCGGTCCGGGGCGTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CCCACGCGCAGGCGTCGGCCGCGACCGCGCTGGCCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TGGGACCTCGGCTCCCCCGGCCCTGGGTCCGGCGCGG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ACATTCGCCGATGCTTGTTCCCGCCGACCGTCGGTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGTTCTCAGGGCTACACGGAGGTGGTCGCGGGACAGC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CACCGCAAGGCAGTGGCGGCGGGCAACGCCGCCAT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GGCGGCCACCGCCATGAGGGATTCGGCCGCGTGGCC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ATCGTGTCGGCACCCGAAACGGACCGGGAGTTTCTCCAA
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CACAGGGATAGGGCCACGTGCGGGACCTCCGAACAG
GTTGCACCGGGCCTCCGGGCTCGGTGAGGATCGCAAC	ACCACGGACGTCGCGGAGATCAGGGACTGGCTGTCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGGGCCTGTGCACGGTCTCGTGCGCACCCGTAGATC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC

>CP025990|38|29|5443903-5445338|CRT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ACCGGGCCCCCCCCGGTCAGGTCGAGGCGGACCAGGGGC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGCTCCAAGGACCCCGGAGAGTTGGGGAGAACGCTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GCGACGATCACGTCCGCCTCGCCGCGTCTGGGCGAGT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TTCGACAACCAACCCATAGTGCTTCTCCTTCTCAG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GCCGGCGTTGAACGGCGGTCGCGGGACGCCAGCGATG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TCCGGACGGATGTGCAGCATCCGCTCGGGGCTGATCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GTGTCGCGGTACGACGGTGGCGAGGCAGACATCCT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TACCTCCGCCAGCTGCTCACCCTGCCCGTGTGGCTGG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GGGGCCGGGGCGGCGGCGGTGGCGGTCCGGGGCGTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CCCACGCGCAGGCGTCGGCCGCGACCGCGCTGGCCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	TGGGACCTCGGCTCCCCCGGCCCTGGGTCCGGCGCGG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ACATTCGCCGATGCTTGTTCCCGCCGACCGTCGGTC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGTTCTCAGGGCTACACGGAGGTGGTCGCGGGACAGC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CACCGCAAGGCAGTGGCGGCGGGCAACGCCGCCAT
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	GGCGGCCACCGCCATGAGGGATTCGGCCGCGTGGCC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	ATCGTGTCGGCACCCGAAACGGACCGGGAGTTTCTCCAA
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CACAGGGATAGGGCCACGTGCGGGACCTCCGAACAG
GTTGCACCGGGCCTCCGGGCTCGGTGAGGATCGCAAC	ACCACGGACGTCGCGGAGATCAGGGACTGGCTGTCCG
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC	CGGGCCTGTGCACGGTCTCGTGCGCACCCGTAGATC
GTTGCACCGGGCCTCCGGGCCCGGTGAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80741.1|5440788_5441688_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl|CDD|377458
CP025990.1|AUS81972.1|5430474_5433417_-|beta-xylosidase	unknown	unknown	gnl|CDD|350118
CP025990.1|AUS80742.1|5442341_5443358_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
CP025990.1|AUS80751.1|5448919_5450206_-|serine--tRNA-ligase	unknown	unknown	gnl|CDD|235461
CP025990.1|AUS80746.1|5446054_5446462_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80752.1|5450539_5451328_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|131480
CP025990.1|AUS80745.1|5445690_5445915_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80744.1|5445478_5445694_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81973.1|5433934_5434921_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380488
CP025990.1|AUS80748.1|5447046_5447940_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
CP025990.1|AUS80743.1|5443361_5443652_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
CP025990.1|AUS80750.1|5448357_5448549_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS80753.1|5451641_5455235_-|AfsR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
CP025990.1|AUS80747.1|5446458_5446944_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP025990.1|AUS80749.1|5447939_5448128_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS81974.1|5441692_5442349_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
CP025990.1|AUS80740.1|5438955_5440731_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
CP025990.1|AUS80738.1|5436044_5438276_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
CP025990.1|AUS80739.1|5438269_5438956_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl|CDD|187782
CP025990.1|AUS80737.1|5434999_5435557_-|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80743.1|5443361_5443652_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	2.8e-27	89.5	0.1
CP025990.1|AUS80740.1|5438955_5440731_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	6e-76	250.8	0.0
CP025990.1|AUS80742.1|5442341_5443358_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	5.2e-112	369.0	0.0
CP025990.1|AUS81974.1|5441692_5442349_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	4.4e-30	99.9	0.0
CP025990.1|AUS80741.1|5440788_5441688_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	1.9e-80	264.8	0.0
CP025990.1|AUS80738.1|5436044_5438276_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	8.9e-50	164.4	0.0
CP025990.1|AUS80739.1|5438269_5438956_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	1.7e-69	228.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80741.1|5440788_5441688_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.464e-107
CP025990.1|AUS81972.1|5430474_5433417_-|beta-xylosidase	gnl|CDD|350118	cd09004, GH43_bXyl-like, Glycosyl hydrolase family 43 protein such as Bacteroides thetaiotaomicron VPI-5482 alpha-L-arabinofuranosidases (BT3675;BT_3675) and (BT3662;BT_3662); includes mostly xylanases. This glycosyl hydrolase family 43 (GH43) subgroup includes enzymes that have been annotated as xylan-digesting beta-xylosidase (EC 3.2.1.37) and xylanase (endo-alpha-L-arabinanase, EC 3.2.1.8) activities, as well the Bacteroides thetaiotaomicron VPI-5482 alpha-L-arabinofuranosidases (EC 3.2.1.55) (BT3675;BT_3675) and (BT3662;BT_3662). It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	1.78953e-143
CP025990.1|AUS80742.1|5442341_5443358_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	2.27515e-131
CP025990.1|AUS80751.1|5448919_5450206_-|serine--tRNA-ligase	gnl|CDD|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	1.41047e-180
CP025990.1|AUS80752.1|5450539_5451328_-|alpha/beta-hydrolase	gnl|CDD|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	9.10168e-40
CP025990.1|AUS81973.1|5433934_5434921_+|LacI-family-transcriptional-regulator	gnl|CDD|380488	cd01574, PBP1_LacI, ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of LacI is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	9.2684e-102
CP025990.1|AUS80748.1|5447046_5447940_+|XRE-family-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.70219e-07
CP025990.1|AUS80743.1|5443361_5443652_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.63132e-28
CP025990.1|AUS80750.1|5448357_5448549_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.37922e-15
CP025990.1|AUS80753.1|5451641_5455235_-|AfsR-family-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	2.44228e-54
CP025990.1|AUS80747.1|5446458_5446944_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.00493043
CP025990.1|AUS80749.1|5447939_5448128_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.19303e-17
CP025990.1|AUS81974.1|5441692_5442349_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	6.79657e-31
CP025990.1|AUS80740.1|5438955_5440731_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	2.32893e-89
CP025990.1|AUS80738.1|5436044_5438276_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.67547e-52
CP025990.1|AUS80739.1|5438269_5438956_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.49037e-84
CP025990.1|AUS80737.1|5434999_5435557_-|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	4.75329e-21

Protein sequences

>CP025990.1|AUS80743.1|5443361_5443652_+|CRISPR-associated-endonuclease-Cas2
MELLISYDVETATREGQRRLRRVAKICEGYGHRVQKSVFEVVCRPQDWVLMKHRLAEVINSERDSIRVYHLDRGSFSRAEHMGASRLAPHESPLVY
>CP025990.1|AUS80742.1|5442341_5443358_+|CRISPR-associated-endonuclease-Cas1
MTEALRTLFISTPGTSLGLDGDAVRITSPDRPGRHLQPLVRLDHLVVNKGVHVSEDLFHRCSEDGRSVTWLSQNGKLLTRTSGRQTGGARLRIEQVRAYDDPARRLALARAFVAGKLHNYRQLVLRIARDRQGGDRELLRDIAADHAATLPRLREADDLDTIRGLEGSAARRYFQAMGVLIPGANPGRTRRPPTDPVNCALSFGYTMLEVATRGAVDEVGLDPFIGYLHDVRPGKASLSLDLMEEFRTMLVDRLVITLFNKKQLSERDMETLPGGEVRFTEEGRKAFLSHWSTARDRMWHHPVLDREVPASTLPLLQARLLARHLRGDTPTYTPWSAG
>CP025990.1|AUS81974.1|5441692_5442349_+|CRISPR-associated-protein-Cas4
MGSSHSEGAGPRPGPEPSVTLGGLEHYAYCPRQAALIHVEQYFEDDAATTRGSLHHEVVDRGDTTRNRRGVRQWNSLPVRSTRLGIHGVCDTVEFGPDGPVPVEHKSGGYRPGGPADVQVAGQVLCLREMFGAEVPHGVVFAGQRRRRHVVEVDAALERRVVDTAERLRELITTGTTPPPVHDSRCRRCSLRPGCVPELRAASPWDPFTPRPLGEWDD
>CP025990.1|AUS80741.1|5440788_5441688_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSNAVPAHLDPTVRHDIVFYFDVTDGNPNGDPDSGNRPRLDLDTQHGLVTDVALKRKIRNTLALAGDGDPRYGIFVEAGHALNTRLLEAASANGAEEEKISTEQVTNTRAWLANRYVDIRLFGAVLSTGSKVTKRLGQIYGPLQVTMARSADPVSPVDHAITRVTQTKKEDIDKGESTEMGGKWTVPYGLYRAELYYSAARGRQTGVDSRDLELLYRSMTMMFDHDRSATRGRLAPRGLHVFSHQDAFGNAPAHTLCERVVAERTEPDNPLPPRSFTDYKLRVDSAALPDGVTLTTVLG
>CP025990.1|AUS80740.1|5438955_5440731_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLVKRLVDHAQRQGTSKPFHRERELHWQLEISTAGRPPLLTRVTDPAATRPGRGVSRQVPAVVRTVGISPNLAADDIQYVLGWADEKTKPERAASCHAAFVDLVTRWAADPAAQDDTLAQAVAAFYQQNGPHGVAEPEGWTSKQGVLLVVDGVPATEAPSVVPYWSTEVARRKAGGAATGLCLSCGTVAPLVDTVPGKVPKKLVPGASNDAALVSVNERVFGYQLTTGLTHTPLCMVCADSMTTGLVAVLSSDHTSSYARQDSKLAWWYSGPPETDWMAQLEQPDPSAVSRLLTSPHEGKAVANGGKDLTRFHALTVSGNIARIMVRDWVEMPLPELERNIRSWFEDIEIVRARGHDRPLRLWTLVLATGRWQPKLKAYAEMGSKSSRRPERLHRQLVATALRNTPPPPELRHHLLARITNDGRVDAYRAALLRLSLVRQYGKDHVMPGLDETNTDPAYLCGRIFTLLQRIQRTALGDVNTSFADRHFAGALSKPDQAVTTGVREAQPWLKKLWRDKTKRGLSVRLDRELARMTTLLEAVALPARFTTAQQSCFVLGYYHQKARYDEEMLAALEKKNKEAEGGPDAEPDTP
>CP025990.1|AUS80739.1|5438269_5438956_+|type-I-C-CRISPR-associated-protein-Cas5
MVKPSSPREEWDPVVVQVWGDAALFTRPELKVERVTYPVMTPSAAVGVLEAIFWKPEFDWRVTAIEVLRPVRQFTQRRNETSDLPPLAEAAKGERRVDTAAHRVQRFALCLKDVAYRIHAQVELRPHATHRAEAYRDQFRRRVRRGACFHQPYLGTREFSAYFGLPDDTPAVETYTEDLGLMIHSIDHSTEPPTTHWFHAEVVRGRMNVPPSGVAVPRATPVGVGGGA
>CP025990.1|AUS80738.1|5436044_5438276_+|CRISPR-associated-helicase/endonuclease-Cas3
MNQLWAHSRNDKGERHTLRDHLISTGELAARFAEPFGAAPLARALGLFHDAGKASCSWQKALLAVEGQDRRTGVPHKEFGAVALRGPAHVAALAVLGHHGGLTRPSDLSDLPDLPAEDSETLRRFLDAVPEAKDFLSGGNLIPENWRRCQSTAEVGIRLVFSALVDADRLDTGAHRAGTEPTVRPAPDMEQLWKRYDQERVNVLAKRAASGKRADPVVDAAREQVYQDAVRAAERPGGLFRMAAPTGSAKTMAAGAFALRHAALHGKSRVIVAVPFTTITEQNAGQYRELLGADVVLEHHSSVDLDTAPRWYRPAAENWDADFIVTTTVQLFDSLFGRKPERSRKLHRLANSVIVLDEVQALPLSLLTPILDVLRVLAEEFGTTVVLSSATQPAFQSLPVWKDFPVTDIVPDPTRLFDDLRRVRYEWWCDPRPTLAEVAEAALDERQCLVVVNTTGNARTVYRHANPDETSPHVLHLSARMCGAHRQQVLHDANRRLNADEPILLVSTQLIEAGVDIDFPVVYRVLAGADAVQQAAGRANREGVLGREGGRVVIVVPEDGGYPGAEYRALAEQTSVHFWAGQDPDRLDALDRYYRGVYSALNLADNRRANAVQRGRAAFDYQSVAEGPLLDAGGAGTARDRELAFRMIDEDTVPVVVDFHGKNKDHKGEGPRLAERLRSSTNPTPRDFRGVQPYVVPLPRALLNRPDIRAICRPVVGDLHEWAGDYHEAYGIDTTDIVQEEVW
>CP025990.1|AUS80737.1|5434999_5435557_-|TIGR03086-family-protein
MSNDNTTGGLYRRLAATFTERVRAVPASGWESQSPCVGWTARDVLAHVVDTQNSVLRKVGIQVPAGPTVETAPLGAWEHTRDAVQDVLDDPMRANRAHDTPFGRSTLAATIGAFYCFDLVVHAWDIAKATGGNTTIPPENLEMVAGFMERMGDTLYSEGVCQPPVPVVGEVNEQTRILALLGRTA
>CP025990.1|AUS81973.1|5433934_5434921_+|LacI-family-transcriptional-regulator
MTDVARLAGVSHQTVSRVLNGHPHVREQTRLRVRAAIDELGYRPNRAARALATGRSQVIGVVAQHSTLYGPASLLAALELASDTAGFAVRVRRVRALDRANILDAVDRLRDDQVAGIVVIAPTLSASEALAAIPTDVPLVTVDGDPDRATALVTVDQVSGAHQATRHLLDIGHRTVWHVSGPPDWFDSAGRVEGWRRALERSGAEVPPVVAADWSAAAGYHAGQALARMPEVTAVFAANDHLALGVLRAMHERGRRVPTDVSIVGFDDVPEAAYFTPPLTTVRPDFDAVAGDALGLLLAQIEDGEVSVARRTREPALVRRDSVTAPPG
>CP025990.1|AUS81972.1|5430474_5433417_-|beta-xylosidase
MVAAALTPALVAASLWSETATATPHPAPPEPEAAAEPYAGYLFAYFTGEGRPDGEQVYLALSRGNDPLRWDELNDGQPVLSSTLGDEGVRDPFLIRSPEGDRFYLIATDLRIHGNGDWDGAQRHGSRSIMVWESTDLVSWSEQRSVEVSPPNAGNTWAPKAHWSEELDAYVVFWASKLYAEDDPDHTGTSHNRMMYATTRDFVSFSEAQVWHDPGHSVIDSAVIEHEGVYHRFTKDERDPDSSSPCAKFLVAERSTELTSTSWDFVADCVGRASEDSPGVERGEGPAVFRANSGDRWHLFIDEFGGRGYVPFETTDLDSGRWTMSSDYRLPPGARHGSVIPLTQAEHDRLAGGPVPPVEADESGLVAHWPLDGAAGEPEAGSRAVDVSGHGYHGTLHGDVRWVGDALEFGGTDGHVALPDHLLSGLDAVTVSADVWVDPAQPTPYFLYGFGNTDRAGVGDGYLFATGGTEDSGLRAALATGDWSTEQQVAAERGLPRGGWRHLTHTVDGGTAVLYLDGVEVARNEGITIRPGDIGGGRTTANYLGRSQYSADHHLTGRLRDVRLHNRALSPEEVAGLSRNGTVIRGVDLPELAVPAVIDPVGATVTLPVEPGTRRQWLSPVLELAPGARVSPDGRRRVDLREPLTYTVTSPSGASRDWTVVARELRTPVLPGYHADPDIAVFGDTYYLYPTTDGFPGWGSTTFSVFSSKDLVNWTDHGVILDLGTDVPWADRNAWAPTITERDGRYYFYFTAAQQVGVAVADSPLGPFEDVGAPLVSANPGGVGQAIDPAAFVDEDGQAYLYWGNGAPFVVPLNEDMVSFDPSSVRRLSGLDEFREGLFVVRRGDTYHLTYSIDDTRSPDYRVGYATADSPLGPFTSHGVILSGDPAQGILGTGHNSVLRVPGTDDWYIAYHRFAVPDGDGTHRETTLDRLTFGADGLAEPVVPTLEGVAPHPVPVPSVATPLDLPGCAGTPGRCAPDDD
>CP025990.1|AUS80744.1|5445478_5445694_-|hypothetical-protein
MTAIVPGPEPVASLMVSTLPALGGKAVTVVVGGDQFVCVLPAACSAAFPADPQLTPPKEAGEFIARAADGF
>CP025990.1|AUS80745.1|5445690_5445915_-|hypothetical-protein
MTTSEPVLLVPGNALGRIIGWMPARCGPVSVLVETSRLGVVLRPEHAPEEPVGLPVMQAHGSRVPCWWRTGKRS
>CP025990.1|AUS80746.1|5446054_5446462_-|hypothetical-protein
MTSPHRTLPRDAWRASVAAVAPTGQPTTVVLTLTADESAAVLLAAGTVGLVAPHAARQFSAALLHRRNLAIPLHVGSSVLRLAVTSLAVPGTGTGGARLALAGNGWGWPLLLGPRPVRQLARVLDEAAGRCRRGW
>CP025990.1|AUS80747.1|5446458_5446944_-|hypothetical-protein
MWQAVNTPVFAIVVTLGPAALMVAAAVLFERENRHREKPRHAVATPPHNSSRPTHPIPVAVLLATRAQDRPDAPPDSPRRARPGAADPDTTAAPFHRPAPPPLGGRHRAATVRPAAAHRERSSPAPRGRRPGAVAPPPDPAATAPIPALTGVLPIWTEPSP
>CP025990.1|AUS80748.1|5447046_5447940_+|XRE-family-transcriptional-regulator
MNDIEAWLTTLWCMARTNLTPLSRALGDAIRKQRTASGLTVRALADKMGLRHTAIVRLEGGTRRAPLDELAALLGTVGTPPDERDRIMAMARDVDRDTWSTSGGSGATAQLATLVRYEREAIALTEANALLVPGLLQVEPYIRSVMEGLPPDVIDARTYYRIGRQQILTRAEPPKMLALIDEAVLARTIGGPAVMAHQMDHLVSLVDAGNVEVRVIPLAAGSAAMMASGWMLVELPDGPPVVHLDHAQAGTMLHTRRDVAAFEQARDTIIAATLNPEASRQMITRYAQSYRSTQSEE
>CP025990.1|AUS80749.1|5447939_5448128_+|DUF397-domain-containing-protein
MTTILTGWRKSTRSDNQSNCVEIGGAPGLAGIRDSKNRGGGVLVVDRQVFAAFIDAVKRDRL
>CP025990.1|AUS80750.1|5448357_5448549_+|DUF397-domain-containing-protein
MTAQELLGWRKARASGPQGDCIEVGGAPGLAGIRDSKNRGGGVLVVDRQVFTAFIDAVKRDRL
>CP025990.1|AUS80751.1|5448919_5450206_-|serine--tRNA-ligase
MLDLDLIRREREAVAAALSKRLDSSEVDRSLSAIVDLDARRRQLLQRIEEERRKRKEASRAYAKAKRESSEPLPPPPDTKAALLALESELENVGAELRQEMAGLPNMPADDVVPGGKENNEVLRVWGEKPALGDFIDHTVVAKEYGLVDFDRGTKLGGSGYWMYTGYGARLEWALLNWFIDQHNAAGYTFVLPPHMLLESAGFAAGQFPKFSDDVYHIANPVSDRPQFLLPTSETALLAAHQDEIFTEAELPRRVFAYTPCYRREKAGTHSDERGTVRGHQFNKVELFQFTTPDGAAEAFESMVDAAEALVRGLGLHFRTSKLAAGDTSATMRRTFDIEVWMPHANGYKEVSSVSWAGDYQARRANIRFRAPQAKQTQFVHTLNGSALATSRLMPAILEQFQQEDGSVLVPEVLRDRVGTDRLVRPTR
>CP025990.1|AUS80752.1|5450539_5451328_-|alpha/beta-hydrolase
MAHATTADGARIWYDGDGDGDPVLLLPGQSLDSRMWGPLATDLAARHRVILMDNRGTGRSEDGAETDYSTALFARDALAVLTAQGIDRAHVYGFSMGGRIAQVLATLAPDRIGALVLAATGPGGTEEVPRSEAANEALRTVSTPAGRAALTELFFTPDWVRDHAELVESVTPSNSRRSQRRHFIASTDHRGWDLLPRITAPTLVLHGGDDALTPPENAHRIAGRVPDARVRIFDGARHGVHLEARPAASDTVLDFLAQNPLD
>CP025990.1|AUS80753.1|5451641_5455235_-|AfsR-family-transcriptional-regulator
MRFGVLGPLAVWTDAGTAVTVPEAKVRLLLAVLLLGEGRPVPTSALVERLWRGRPPGNPVNTVQTKVSQLRRALDRAEPGAGALVVRQPPGYLLAVAGSDLDLRRFRGLVAEARAARDPEVRAGRLGEALAVWRGPALADLAAEPAAVAAASVWEEERLVATEEWAEARLRLGDHAGLAVELTPTVARHPIRERLRERHLIALYRAGRQAEALAGYEELRHRLREELGVDPSPPVAALHRAILRQDPALAAPSPPAPAAGTAAPLPTALTTLVGREAAVAELVAVLRQQRLVTLTGPGGVGKTRLAIEVARRLSTQHPDHPPPVHPTSGPPPAAPAEDPDTEAPVTARLVELAGLDAPGPDHGDPVDRVAEAVASALGLRDVLGGASDEPHHPRTGERLAAALHHRDWLLVVDNCERLVAAVADLAALLLARVPSLRVLATSQEPLGLAGERVWPVPPLSLPAPASAPAAEIEVRAGAERSDAVRLLVDRAADTTPGFALTDGNARALAAVATRLDGIPLALELAAARIRALGPEELLRRLDDRFRLLTRGPRDAPDRQRTLRATLDWSWEPLSEPERLLLRRLAVHRDGFDLAAAEDVGPGGTVAREEVVDLLTTLVDRSLVTPVDGGTGLPRYRLLESVAAYGRDRLAEAGELDAVRRRHAAHYLGLAERADDGVRGPEQRRWLHRLDAETANLRHALDTATSCGDVDTALRLVTSLVWSWFLRGRTAEARRSLRAALAVPGADHHPAGETASAWLAGLLDLDGHPVDPGLRPGWARVHPEPAPPAPAGTAPARPDPAHRADGTRRPAPLPPAGPSGEADPAGRAVPAGPPGDADPAGQAAPAVSSEDPATTGSALLARGRALWFLGYVTSTLGDLVAGSQLTDRALTLIEARGDTWGVAAALADRANQRMGRGDFPASHAAATRSRELFRGLGDRWGQLQGAFVLGALAELAGDYPRAERLHQEGLRGAEGLRLWPEVSYQLSWLGRIALLTGDHTRARDLHERARTVALEQDFTPGRLYAETGLALGARREGRWDEAERLLLDLADWHRTTSFEPASTLILAELGFVAEQRGDAVTALRLHDEGLTTARRLVDPRATALALEGLAGGHSLAGNATRAARLLGVATGLRAGIGTPLPAAERLDVDRITTRARGALGPDRFAAEFDAGTSWVAVAGADALRDLDAVLGDSPPGAT

Crispr_ID: CP025990_39

• CRISPR_ID: CP025990_39
• CRISPR_location: 5574061-5574637
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of CP025990_39

Consensus_repeat	Method
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	PILER-CR
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CRISPRCasFinder
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CRT

spacers of CP025990_39

>39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CCCTGCGCGGCCGCCGTGTGCCATGCCACCGC
>39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
>39.3|5574212|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTCAGTTCCTCTTACGGGAGGTCCTCCCGAAT
>39.4|5574273|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
TGCGTCATCCTCGGCAGGTCAGTAGCGAACCG
>39.5|5574334|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCGGCGCGCGTGCGTATGCGTATCAACGGCAC
>39.6|5574395|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGCCGATATCGCGGAATTGGCACACCAGTGC
>39.7|5574456|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGCCGATATCGCGGAATTGGCACACCAGTGC
>39.8|5574517|32|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGCCGATATCGCGGAATTGGCACACCAGTGC
>39.9|5574578|31|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGCTCATGAGGGATCGCGGGACCGAGGTCGG

CRISPR arrays and Neighbor proteins around CP025990_39

CRISPR arrays

The CRISPR arrays of CP025990_39

>merge|CP025990|39|5574061-5574637|PILER-CR,CRISPRCasFinder,CRT
CGGCTCACCCCCGCTCGCGCGGGGCAGACCCCTGCGCGGCCGCCGTGTGCCATGCCACCGCCGGCTCACCCCCGCTCGCGCGGGGCAGACCGGATGTCCGCGACGGCGGCCTCGCGGGATGTCGGCTCACCCCCGCTCGCGCGGGGCAGACGTCAGTTCCTCTTACGGGAGGTCCTCCCGAATCGGCTCACCCCCGCTCGCGCGGGGCAGACTGCGTCATCCTCGGCAGGTCAGTAGCGAACCGCGGCTCACCCCCGCTCGCGCGGGGCAGACGCGGCGCGCGTGCGTATGCGTATCAACGGCACCGGCTCACCCCCGCTCGCGCGGGGCAGACCGGCCGATATCGCGGAATTGGCACACCAGTGCCGGCTCACCCCCGCTCGCGCGGGGCAGACCGGCCGATATCGCGGAATTGGCACACCAGTGCCGGCTCACCCCCGCTCGCGCGGGGCAGACCGGCCGATATCGCGGAATTGGCACACCAGTGCCGGCTCACCCCCGCTCGCGCGGGGCAGACCGCTCATGAGGGATCGCGGGACCGAGGTCGGCGGCTCACCCCCGCTCGCGCGGGGCAGAC

>CP025990|39|31|5574061-5574637|PILER-CR
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CCCTGCGCGGCCGCCGTGTGCCATGCCACCGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GTCAGTTCCTCTTACGGGAGGTCCTCCCGAAT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	TGCGTCATCCTCGGCAGGTCAGTAGCGAACCG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GCGGCGCGCGTGCGTATGCGTATCAACGGCAC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGCTCATGAGGGATCGCGGGACCGAGGTCGG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC

>CP025990|39|37|5574061-5574637|CRISPRCasFinder
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CCCTGCGCGGCCGCCGTGTGCCATGCCACCGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GTCAGTTCCTCTTACGGGAGGTCCTCCCGAAT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	TGCGTCATCCTCGGCAGGTCAGTAGCGAACCG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GCGGCGCGCGTGCGTATGCGTATCAACGGCAC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGCTCATGAGGGATCGCGGGACCGAGGTCGG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC

>CP025990|39|30|5574061-5574637|CRT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CCCTGCGCGGCCGCCGTGTGCCATGCCACCGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGATGTCCGCGACGGCGGCCTCGCGGGATGT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GTCAGTTCCTCTTACGGGAGGTCCTCCCGAAT
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	TGCGTCATCCTCGGCAGGTCAGTAGCGAACCG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	GCGGCGCGCGTGCGTATGCGTATCAACGGCAC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGGCCGATATCGCGGAATTGGCACACCAGTGC
CGGCTCACCCCCGCTCGCGCGGGGCAGAC	CGCTCATGAGGGATCGCGGGACCGAGGTCGG
CGGCTCACCCCCGCTCGCGCGGGGCAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS80821.1|5569955_5570720_+|hypothetical-protein	unknown	unknown	gnl|CDD|379263
CP025990.1|AUS80820.1|5568994_5569708_+|thiaminase-II	unknown	unknown	gnl|CDD|381700
CP025990.1|AUS80815.1|5563920_5564328_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80823.1|5574861_5575635_-|5-formyltetrahydrofolate-cyclo-ligase	unknown	unknown	gnl|CDD|223290
CP025990.1|AUS80818.1|5567975_5568194_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80816.1|5564567_5565383_+|TIGR03619-family-F420-dependent-LLM-class-oxidoreductase	unknown	unknown	gnl|CDD|274680
CP025990.1|AUS81983.1|5565601_5567068_-|MFS-transporter	unknown	unknown	gnl|CDD|184957
CP025990.1|AUS80819.1|5568398_5568731_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B	unknown	unknown	gnl|CDD|235501
CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
CP025990.1|AUS80829.1|5581129_5581642_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
CP025990.1|AUS80822.1|5571215_5572223_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|181818
CP025990.1|AUS81984.1|5572692_5573904_+|MFS-transporter	unknown	unknown	gnl|CDD|341042
CP025990.1|AUS80817.1|5567282_5567675_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133388
CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
CP025990.1|AUS80826.1|5577912_5578425_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|281995
CP025990.1|AUS80825.1|5577477_5577879_-|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|133388
CP025990.1|AUS80824.1|5576721_5577234_-|hypothetical-protein	unknown	unknown	gnl|CDD|379235

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.47506e-12
CP025990.1|AUS80821.1|5569955_5570720_+|hypothetical-protein	gnl|CDD|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	1.61401e-74
CP025990.1|AUS80820.1|5568994_5569708_+|thiaminase-II	gnl|CDD|381700	cd19365, TenA_C-like, uncharacterized TenA_C proteins. This family of TenA proteins belongs to the TenA_C class as it has a conserved active site Cys residue; the double Glu residues identified in the active site of TenA_E from the archaeon Pyrococcus furiosus is conserved in this family. TenA_C proteins (EC 3.5.99.2) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect. This family includes mostly uncharacterized TenA_C- like proteins.	4.08323e-94
CP025990.1|AUS80823.1|5574861_5575635_-|5-formyltetrahydrofolate-cyclo-ligase	gnl|CDD|223290	COG0212, COG0212, 5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism].	1.26099e-22
CP025990.1|AUS80817.1|5567282_5567675_+|MerR-family-transcriptional-regulator	gnl|CDD|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.02546e-37
CP025990.1|AUS80816.1|5564567_5565383_+|TIGR03619-family-F420-dependent-LLM-class-oxidoreductase	gnl|CDD|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	4.6733e-57
CP025990.1|AUS81983.1|5565601_5567068_-|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	2.84288e-76
CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B	gnl|CDD|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.1672e-25
CP025990.1|AUS80822.1|5571215_5572223_-|AraC-family-transcriptional-regulator	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	2.05158e-112
CP025990.1|AUS81984.1|5572692_5573904_+|MFS-transporter	gnl|CDD|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.78457e-36
CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.10376e-56
CP025990.1|AUS80826.1|5577912_5578425_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl|CDD|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	2.93194e-24
CP025990.1|AUS80825.1|5577477_5577879_-|MerR-family-DNA-binding-transcriptional-regulator	gnl|CDD|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.50886e-33
CP025990.1|AUS80824.1|5576721_5577234_-|hypothetical-protein	gnl|CDD|379235	pfam13521, AAA_28, AAA domain.	9.47637e-10

Protein sequences

>CP025990.1|AUS81984.1|5572692_5573904_+|MFS-transporter
MHRRTLRAVVASQVLGGAGLAAGVTVGALLAEEMLGSDRLAGLPAALFTLGSALAAFLVGRCVQRWGRRVGAGLGFAAGGLGAAGVVVASATGSVPLLFVSLFVYGSGTATNLQARYAGTDLAPPSRRGAAISVAMVSTTLGAVAGPNLVDPLGRFATTLGLPGLAGPFLLAAVAYPVAGLVLFVLLRPDPYLLARALHEAERARDDTRSPGVPKPRVGAYVGAAVMVLTQIAMVAIMTMTPVHMRAHHHDLSAVGLVIGLHVGAMYLPSLVTGMLVDRVGRTRMAAASGVTLLAAGVVAALAPGDSLGPLILALVLLGLGWNFGLISGTALVVDATVPENRPRTQGSIDVLVSLAGAGGGAMSGVVMATGGYEVLSLAGGLLALLLVPVLLWAARRDREVTS
>CP025990.1|AUS80822.1|5571215_5572223_-|AraC-family-transcriptional-regulator
MRGDPGSRERHGEPHRVVVLAIDEVVGYDLSIPPQIFGAAKRGERDLYDVRVCGVDRRPVRVESGYTAVLDHGPEALEDAQTVIVPGTRARGPRVDGVLTPEIAEALARIPPGARIMSICTGAFVLAAAGLLDGRRAATHWAHVDAFRRLHPRVELDEDVLFVDDGDVLTSAGLGAGVDLCLHVVRSDHGTAVSNLAARSCVVPPWREGGQSQFIERPLPETGEGSTAATQEWASRRLADPLDVAALAEHASMSVRTFSRRFRAETGLPPGAWLIQQRVSHARQLLETTSLPVDRVAAEAGLGSAASLRAHLNAAIGVSPLAYRRTFTPPAGTTR
>CP025990.1|AUS80821.1|5569955_5570720_+|hypothetical-protein
MTARFDGNVVVVTGAGQGIGAAIARSFAEQGATVVVTDIRADTATTTAIEINAATGATVLARPLDVTRSAEVAALADQVVAEHGRVDVLVNNAGIVLGAASFDYDDDTWNRTLAVNLSGPFYTAREFGRRMRGRGGAIVNVSSVAALRAPRADPHIGYDATKAGVIALTRSLAAEWAPEGIRVNAVAPGYTNTDILKAVGSENPEVVAGWRSHIPQGRLAEPVEIAQAVRFLASTEASAVTGHVLVADGGYSTW
>CP025990.1|AUS80820.1|5568994_5569708_+|thiaminase-II
MTGFSARLWNETAALQREMTLLPFNVELAEGTLSRDRFHFYLAQDARYLVGFGRALAAAAARAPDVDDVAFLAGAAREAIEVERALHAGYFARYGLGQDDLDRIETSPTCLAYTSYLAALATTGSFGELVAGLLPCFWVYHEVGTDIVRRQRTGPPRITDHPYQAWIDTYADEEFGRAVARCRQAVDRAAASAGAAERAAMTRAFTRASEYEWLFWDSAYRCEQWPTRRFLPTPGER
>CP025990.1|AUS80819.1|5568398_5568731_-|hypothetical-protein
MRATVRGLLLAAAVGGAVVSVAPAVSAATIPADVCSPASVVEVASCTPYWKQSEGHSSKSFCDWAGSSGAQAGRWTGWNCSQALNGWELWVRTCTARAGETPASREESTV
>CP025990.1|AUS80818.1|5567975_5568194_-|hypothetical-protein
MGNGLLAARLTAAERSRRPGVGRPCSVPVSRDGTAATWTSAAVTTGASALTSSAVLWSGPVPPAGQDDDREA
>CP025990.1|AUS80817.1|5567282_5567675_+|MerR-family-transcriptional-regulator
MRIGELSRRAGVSVRALRYYEEQGLLRPRRRPSGYREFGDGDVALVARIQALISAGLNTQHIAEVLHCFDEGGAGSVPTPTCAEMVEELAEARARMRNRIEDLSTSVELLTAIIDAAPEEHQDSPAAIGA
>CP025990.1|AUS81983.1|5565601_5567068_-|MFS-transporter
MDITVLHLAVPALSADLDPTGTQLLWILDVYGFVVAGFLLVMGALGDRIGRRRLLMVGAAAFAVVSVLAAFSSSAELLIAARALLGVAGATLMPSTLAVLTDVFRTPARRTFAVAVWMTAFTSGEAVGPLVGGLVLEFLWWGAVFLVGVPVMVLLLVVGPFVLPESAERLPGRFDLASATALLASVLSFVYGVKELASRGGWEPLGWIAAGLVLGCLFGWRQLRTRDPLLDLRLFRRAPFSAGFVAQLLAVAAMAGSQLLVMQYLQSVLGLSPFEAGLWTLPSVLLGIGATLLAPRLVRHSSAAPVVATGLFAAAVGATALAVTSHHLDLGSTVLGFTVLYVGVTPTLALMTDLIVGSAPRGRAGMAAGVAESGAEFGLAGGMAFIGTVASATYSSRVLSDASGGVAVEHLQEASRTVGNAVALAQDLPPEVGTSLLDAARMAFADGMRLAATVSAVLLVVGGALALRFLRPARSTTPGDHAAGARAE
>CP025990.1|AUS80816.1|5564567_5565383_+|TIGR03619-family-F420-dependent-LLM-class-oxidoreductase
MRLEVVLPDESPTMPARRIAELARAAEDLDYDTAWLPDHILPPDEYGAVFGGVYEPLVTIGHLSAATRRLRLGTSVLVVPLRDPFVLAKQVATLHHLSEGRFVLGVGVGWNEQEFQAVGAEYPRRGAITDDTLDLLRHLLAGGAAPYRGRRYSFDVGVFEPVPAGPVPLMVGGNSDAALRRAARHGDSWQGLPTSPPVFAERASALAALAGDRHVTPTLRIGWDGGGPVERTVDDLLAYREAGAEAVAVHFGDHEGFAQRMEELRRALDTL
>CP025990.1|AUS80815.1|5563920_5564328_-|hypothetical-protein
MTNGGQAEREPVVLTVGLRPDAVDLSGHPDLDHEALAARIASGQEALRREGIDNTTCLVSADPEEAERRIREEVAGRHFDLVVIGGGVRLDPEQTVLFERILNLLIDLVPGVRFCFNTSPETTLDAIRRWSPQPR
>CP025990.1|AUS80823.1|5574861_5575635_-|5-formyltetrahydrofolate-cyclo-ligase
MADPLEDLKDKARAHVWDRLAAAAAVHDPDVHGRIPNFISAGAAADRLAELPVWKSAHVIKTVPDKAQRAVRARALRDGKLVYMAVPKLARERPFCLLDPAQLEVPPEQAADSHRAIALAPTVDVDEVRPVDLVVCGSVAVNRRGVHLGKGAGYSDLEVALLREAGRIGPETVIATTVHALQVVDEDLPESDHDFSVDLIVTPEQVIECGPRRRPAGLMWERLPAEKIAAIPVLRRRASDRRSRPAGPGDGHRPGHG
>CP025990.1|AUS80824.1|5576721_5577234_-|hypothetical-protein
MNSFNAVGSKSIDARSAPRRSTQSRSYPPRDRSLNSGQLRTDSSRATSRATKKCAEYTAHTRGTRFYNRGIPDGYGWEGFFGLKPTTELEEATRRYRYDAIFVLDPLDTFEDPDDIVWAKDREIRRVHALIVQGYYDAGYEPVFVAPDSATARLDFICANLRLPKPSRGA
>CP025990.1|AUS80825.1|5577477_5577879_-|MerR-family-DNA-binding-transcriptional-regulator
MERMVSAVDQRDWLRIGELARRTATSTRSLRYYEQRGLIVSDREHNGYRRYAPDVVPVVNNIRRLLNAGLSIDDIKQFGSCVRSPSLDATPCAPALEVYEQRLKILRTRIDTLQHLHAALAEQTEHLRAQLPS
>CP025990.1|AUS80826.1|5577912_5578425_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MPDDIQDWNRRIVSEFRSNAGFVRWSTEKDLAEGRPIPPPLPSFDPRQSVPIILVNHIGAVTGRRRTSPLMYQAVRDAFAVFATFGGSPRPPAWYHNIVRNPEVVVEVGSDVTGAIARVVQGEEREDIWVEQARLVPAFADFEKTARRRIPVVVLDPIPSPAAMRAHGAS
>CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator
MTITVLLADDERLIRSALATLLPLEGDIDVVAEAGTGTEAVAAFERLRPDVAVLDLEMPELDGLHAAERILNQAPGQAVLMLTRYARPGTLRSALRLGVRGFLGKDSEASLIASAVAEVAAGGRYVDANISAQALIDDCPLTERERDVLRVAGDGYSVKDMAKILHLAPGTVRNYLSSAIQKTHTNTRHDAARYAREHDWL
>CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase
MTRRDPSPHGGKDTAPAPEASVAARQTIRQREIRSFVISIVVMAGAGLVTTTVWWTALVAIPSLALSTALLFRGWDRPPNPLLLAGSGLLGVLALVVTSLTYSNFTGSTGLAITAGVWIAHRPRDRLVLTLLACLGIAALTWATALLSGNSGGVYQLVVMMSITGSVWIVALVESHTQDRLFDLLEREKDHERELSILRERNRFAADLHDIQGHTLHVIKLKAAVAAKLQHTDPERTRQELEVIQRLVADTIGQARQLANSTHALVFSTELSNAVELFRAAGITTRVDRTEDDPGPHEAHFALALREATTNVLRHARPGEVTITSSADTLSVRNDGADIKDAAPLRGLATLADRVRAVGGTLTADRDGGVHTLTVTFPTEAR
>CP025990.1|AUS80829.1|5581129_5581642_+|hypothetical-protein
MESNFITDLFAQLAEFAAGAETWQQVGVLLIAGAIPFIESYLGSFLGVLVGVPAGLAVPAAILGNVIVTFALIALASKARVAATRRRGNGGGGGADAPRRKQKIAKYLDRFGVPGVCLLGPIVVASQITAPALVALGATKRSVYVWQAVAIVAWGVLFGFFGDLAAGWFM
>CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A
MARRKGSAQTKVDPTAFDQPGRHVVDNPVHTEIEDSYLEYAYSVIHSRALPDARDGLKPVHRRILFSMHEQGYRPTHAYVKSSRVVGDVMGKYHPHGDTAIYDAMVRLAQDFSMNVPLVDGHGNFGSPDDGPAASRYTEARMSPAALQLVAELGEDTVDFRPNYDGSLEEPAALPAAFPNLLVNGTSGIAVGMATNMIPHNLGEVVAAARWLIRHPDAPLDKLMEFVPGPDLPTGGMLLGLDEVRKAYETGRGVVRMRAKVETGPLPGSRGRQAITVTELPYGVGPEKIIEKITDEVNKSKRLTGVADVKDLTDRENGTRLVIECKVGVNPQALLADLYRLTPLEQSFGINNLVLVDGEPRTLGLKELLEVFLAHRFEVVRRRTTFRRRKRSDRLHLVEGLIRALVDIDRVIRLIRESDDAKAAKEGLIARFDLSEIQATYILDTPLRRLTKYDKVELEEERERLTGEIAELSRILDDEAVLRRLVSTELGRIAKEFPTERRTTLIDGDLKEVLAASKPAGPLEIADDPCQVILSATGLVSRTAAASEEAAEARRRNGRVRHDAVAAVVDSTARGQVVLVTSHGRGIKTDVLPLPVLPQQSGIVSLRGGMPVRELVSLAPGERVLGLAPLGDQIGDSPGLALGTRQGVVKVCSPEWPVRADEFELIALREGDEVVGVTWLADGQESLVFVSSDAALLRYSATLVRPQGLRGGGMAGINVKGDARVVFFGAVAEDGEPVVITATGETVKVTPFGEYPAKGRATAGVRAQRFLATESELSTAWVGARPAPSTGNGTPVELPDPDERRDGTGAPAEIPVVVGYLLERD
>CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B
MTASAETIYGADDLTHLEGLEAVRKRPGMYIGSTDSRGINHLFSEVVDNSTDEGVAGYATRIVVTLHADGSVQVDDDGRGIPTGVHAKSGISGVELVLTRLHAGGKFGGSGYKTSGGLHGVGASAVNALSHRFDVTVRRDGLVHQMSFAHGAPGVFDGPGARAKFTPRSGLHVTGKMKRDETTGTSIRYWHDARYFETGAALDVEGVRSKLRNTAFLVPGVTYVLRTATEDSISEETFHFPNGLPDMVDFLAPTGDRAVSGTLVVSGEGTYKENAADENGVMQSNVPRRAEVEVAFRWGTGYERTVECFTNTIRNVHGGTHRKGFERAAVKALHAAIARTRGLLRAKEEPPTLEDVLEGMTAVIHVRIPEPQFTSQTKDELSTAGITKVVQAVVEAHLREWTEDRRTKVEAKTVLQKIVDASRVRLTQKQQKDAARRKTALEGAAMPAKLVDCRTTGVARSELFLVEGDSALGSARLARVSEYQALLPLRGKILNVQKASLADTLRNAEIASIVQVLGAGSGRTFDLSAMRYGRVILMADADVDGSHIRTLLITLFAKYLRPVIEDGRLYAAMPPLHKITTRGRKPQTHFTFTQREMESTVARLEKAGKQVVTPVPRFKGLGEMDADELWETTMNPATRSVRRITLAEADAAAADEALDLLMGEKVEPRRAWLVRSAARVDRAAIDV
>CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator
MVIRFGGVRVASDERDDAAASGDTRRDRAGRILDAASALTLRWGYQKTTIDDIARAAGVAKGTIYLHWKSRDALFLALLRRERALAATEIRDLAAQDPAGHTLRGVLVHSYRVVARRPLLLAVLTRDRDVLGRLLTTGAPTARPPLSVGFPRYLEHLRAGGWVRTDQTLAAQLSLGTATIYGFLLTRPLMPDEFAVTDDDAAELVADTVCRALDRGSPLGDTETEGVAAASAAYLAEAARFTIERYENEVA

Crispr_ID: CP025990_40

• CRISPR_ID: CP025990_40
• CRISPR_location: 5592070-5592343
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: WYL

Consensus repeat of CP025990_40

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGACGAC	PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRT

spacers of CP025990_40

>40.1|5592098|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGCCTTCGAGTTCTCCGAAGCCGATCTGACGAA
>40.2|5592159|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCCCCGAAGAACGACCCCAGCAGCAAGCCCCC
>40.3|5592220|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
ACAGCCATTGTGGCCAGCTTCGAACTGATCGGG
>40.4|5592281|34|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCGTGATGCATCGGCGCTCCGGTGAGC

CRISPR arrays and Neighbor proteins around CP025990_40

CRISPR arrays

The CRISPR arrays of CP025990_40

>merge|CP025990|40|5592070-5592343|PILER-CR,CRISPRCasFinder,CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCCGGCCTTCGAGTTCTCCGAAGCCGATCTGACGAAGTCGTCCCCGCGCACGCGGGGCTGTTCCGCCCCCGAAGAACGACCCCAGCAGCAAGCCCCCGTCGTCCCCGCGCACGCGGGGCTGTTCCACAGCCATTGTGGCCAGCTTCGAACTGATCGGGGTCGTCCCCGCGCACGCGGGGCTGTTCCGTCGCACTCGTGATGCATCGGCGCTCCGGTGAGCGTCGTCCCCGCGCACGCGGGGCTGTTCCC

>CP025990|40|32|5592070-5592342|PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGCCTTCGAGTTCTCCGAAGCCGATCTGACGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCCCGAAGAACGACCCCAGCAGCAAGCCCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ACAGCCATTGTGGCCAGCTTCGAACTGATCGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTCGCACTCGTGATGCATCGGCGCTCCGGTGAGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC

>CP025990|40|38|5592070-5592343|CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGCCTTCGAGTTCTCCGAAGCCGATCTGACGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCCCGAAGAACGACCCCAGCAGCAAGCCCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ACAGCCATTGTGGCCAGCTTCGAACTGATCGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTCGCACTCGTGATGCATCGGCGCTCCGGTGAGC
GTCGTCCCCGCGCACGCGGGGCTGTTCCC

>CP025990|40|31|5592070-5592342|CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGCCTTCGAGTTCTCCGAAGCCGATCTGACGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCCCGAAGAACGACCCCAGCAGCAAGCCCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	ACAGCCATTGTGGCCAGCTTCGAACTGATCGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTCGCACTCGTGATGCATCGGCGCTCCGGTGAGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|334450
CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187578
CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS81985.1|5597835_5598090_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B	unknown	unknown	gnl|CDD|235501
CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein	unknown	unknown	gnl|CDD|176531
CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378976
CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase	unknown	unknown	gnl|CDD|376527
CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|224877
CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
CP025990.1|AUS80826.1|5577912_5578425_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|281995
CP025990.1|AUS80837.1|5594966_5595785_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80825.1|5577477_5577879_-|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|133388
CP025990.1|AUS80829.1|5581129_5581642_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase	unknown	unknown	gnl|CDD|223082

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	1.5e-34	114.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.47506e-12
CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	2.37513e-13
CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.54865e-62
CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.1672e-25
CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B	gnl|CDD|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein	gnl|CDD|176531	cd08589, PI-PLCc_SaPLC1_like, Catalytic domain of Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1-like proteins. This subfamily corresponds to the catalytic domain present in Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1 (SaPLC1) and similar proteins. The typical bacterial phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) catalyzes Ca2+-independent hydrolysis of the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). The catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. In contrast, SaPLC1 is the first known natural Ca2+-dependent bacterial PI-PLC. It is more closely related to the eukaryotic PI-PLCs rather than the typical bacterial PI-PLCs. It participates in PI metabolism to generate myo-inositol-1-phosphate and myo-inositol-1:2-cyclic phosphate simultaneously. SaPLC1 and other members in this subfamily have two Ca2+-chelating amino acid substitutions which convert them from metal-independent enzymes to metal-dependent bacterial PI-PLC. Additionally, SaPLC1 active site utilizes a mechanism of amino acid juxtaposition, swapping amino acid positions, to adapt a calcium binding pocket and maintain more ideal active site geometry to support efficient catalysis.	1.59541e-77
CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.3125e-27
CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	5.85638e-41
CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase	gnl|CDD|376527	pfam01326, PPDK_N, Pyruvate phosphate dikinase, PEP/pyruvate binding domain. This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP).	3.18964e-96
CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A	gnl|CDD|224877	COG1966, CstA, Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms].	4.0558e-146
CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.10376e-56
CP025990.1|AUS80826.1|5577912_5578425_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl|CDD|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	2.93194e-24
CP025990.1|AUS80825.1|5577477_5577879_-|MerR-family-DNA-binding-transcriptional-regulator	gnl|CDD|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.50886e-33
CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	8.41336e-58

Protein sequences

>CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator
MADVTQRSLALLAALRNGQPVSGEELARLLEVDQRTIRRDVERLRGYGYEVDAQPGPGGYYRMPGGNTVPPIPGAVAGADGPPAAEAADHALSENGGEPLAATGRRALDQLTQHPATRTTEHCLPGDVDAAGEPGWRTGTGGDSADLVGAALQRCRVLTFDYTDAAGVVSTRRVEPHRRMHQLMRWYLLAWDAGRRDWRVFRMDRISEPRVEEASFAPRPLPPDDGVGYPHWTTHRSPLRVVVTVEAPVAAVADVLRHQQVEFLAVRPDRTRAVLAVESWQWLVLNLAFLDVEFTVEEPEEVRSACASFASRLGLASTSAPVAP
>CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase
MRSPLVDNEVTHPFVLPLGAGGADLALVGGKGASLDRLVSAGLPVPAGFHVTTTAYRAAHGDHPRPPRRPGTGAGLAEPGATRAGTADPGPWPVPPEVADAVTAAYRELGPDAPPVAVRSSATAEDLPELSFAGQQDTFLNVRGERDLLHALTRCWASLWTPRAVAYRERHDVDPATVAMAVVVQLLVPARAAGVLFTANPLTGSRDELVINASWGLGESVVSGQVNPDTVIVDQRTGRTSHHTTSAKTVRTVPADGGVREEAVDDHLVHAPVLTEQDITRLADLGRRVDALHERPSDVEWALDDSGTPHLLQARPITGLPAPRLPATGQHTTPARPPSSAPPEDTTTRTPAEGRPPATSPPRPRHHRGSGTASRREEWNDSRLGDYLWTNGNLGEAIPSVMTPATWSFVQVFMLRTMGIPSCQGHPTWGNIGGRFYLNLSTSLSLGTAFGRTVDQMADTVSAVFGRIPPGTPVPVIPLRRWATLRELVPLVTAFRLRLRIAHRRLASYLDTAADRCAALRARARTAPTPDALLRLWRTELWPYCLETFDMMSAAARGRGGGNRLVKVRQRLAEQVGEADANALTTGIAHGAPLASLGPLLGLASVANGDTSPEDHIRQWGHRCPDEFEISLPRPAEDPTWLDHQLAAFRDSRTDVHAMLTQRRAEHEQAWARYQRDHPRHVTRTRRELRSWARLVHDREATRSEVNRAFWAIREVVLRAGELTGHGHDLFLLERHEIERVLAGDDRPLAAVPARRDAYERYRALPNYPTLIRGPFDPERWAADPRRRTDLYDAATAPSSPEHPEPANHHSRTAGAPRPAATTPEPERKPAPNPITGFPGAVGTVEGVARVVTSVDDAQDLRAGEVLVTTATNVGWTPLFPRAAAVVTDVGAPLSHAAIVARELGIPAVVGCGNATMRIRTGDRLRVHGERGEVHLIDPPTEGGAPPTGA
>CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator
MVIRFGGVRVASDERDDAAASGDTRRDRAGRILDAASALTLRWGYQKTTIDDIARAAGVAKGTIYLHWKSRDALFLALLRRERALAATEIRDLAAQDPAGHTLRGVLVHSYRVVARRPLLLAVLTRDRDVLGRLLTTGAPTARPPLSVGFPRYLEHLRAGGWVRTDQTLAAQLSLGTATIYGFLLTRPLMPDEFAVTDDDAAELVADTVCRALDRGSPLGDTETEGVAAASAAYLAEAARFTIERYENEVA
>CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B
MTASAETIYGADDLTHLEGLEAVRKRPGMYIGSTDSRGINHLFSEVVDNSTDEGVAGYATRIVVTLHADGSVQVDDDGRGIPTGVHAKSGISGVELVLTRLHAGGKFGGSGYKTSGGLHGVGASAVNALSHRFDVTVRRDGLVHQMSFAHGAPGVFDGPGARAKFTPRSGLHVTGKMKRDETTGTSIRYWHDARYFETGAALDVEGVRSKLRNTAFLVPGVTYVLRTATEDSISEETFHFPNGLPDMVDFLAPTGDRAVSGTLVVSGEGTYKENAADENGVMQSNVPRRAEVEVAFRWGTGYERTVECFTNTIRNVHGGTHRKGFERAAVKALHAAIARTRGLLRAKEEPPTLEDVLEGMTAVIHVRIPEPQFTSQTKDELSTAGITKVVQAVVEAHLREWTEDRRTKVEAKTVLQKIVDASRVRLTQKQQKDAARRKTALEGAAMPAKLVDCRTTGVARSELFLVEGDSALGSARLARVSEYQALLPLRGKILNVQKASLADTLRNAEIASIVQVLGAGSGRTFDLSAMRYGRVILMADADVDGSHIRTLLITLFAKYLRPVIEDGRLYAAMPPLHKITTRGRKPQTHFTFTQREMESTVARLEKAGKQVVTPVPRFKGLGEMDADELWETTMNPATRSVRRITLAEADAAAADEALDLLMGEKVEPRRAWLVRSAARVDRAAIDV
>CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A
MARRKGSAQTKVDPTAFDQPGRHVVDNPVHTEIEDSYLEYAYSVIHSRALPDARDGLKPVHRRILFSMHEQGYRPTHAYVKSSRVVGDVMGKYHPHGDTAIYDAMVRLAQDFSMNVPLVDGHGNFGSPDDGPAASRYTEARMSPAALQLVAELGEDTVDFRPNYDGSLEEPAALPAAFPNLLVNGTSGIAVGMATNMIPHNLGEVVAAARWLIRHPDAPLDKLMEFVPGPDLPTGGMLLGLDEVRKAYETGRGVVRMRAKVETGPLPGSRGRQAITVTELPYGVGPEKIIEKITDEVNKSKRLTGVADVKDLTDRENGTRLVIECKVGVNPQALLADLYRLTPLEQSFGINNLVLVDGEPRTLGLKELLEVFLAHRFEVVRRRTTFRRRKRSDRLHLVEGLIRALVDIDRVIRLIRESDDAKAAKEGLIARFDLSEIQATYILDTPLRRLTKYDKVELEEERERLTGEIAELSRILDDEAVLRRLVSTELGRIAKEFPTERRTTLIDGDLKEVLAASKPAGPLEIADDPCQVILSATGLVSRTAAASEEAAEARRRNGRVRHDAVAAVVDSTARGQVVLVTSHGRGIKTDVLPLPVLPQQSGIVSLRGGMPVRELVSLAPGERVLGLAPLGDQIGDSPGLALGTRQGVVKVCSPEWPVRADEFELIALREGDEVVGVTWLADGQESLVFVSSDAALLRYSATLVRPQGLRGGGMAGINVKGDARVVFFGAVAEDGEPVVITATGETVKVTPFGEYPAKGRATAGVRAQRFLATESELSTAWVGARPAPSTGNGTPVELPDPDERRDGTGAPAEIPVVVGYLLERD
>CP025990.1|AUS80829.1|5581129_5581642_+|hypothetical-protein
MESNFITDLFAQLAEFAAGAETWQQVGVLLIAGAIPFIESYLGSFLGVLVGVPAGLAVPAAILGNVIVTFALIALASKARVAATRRRGNGGGGGADAPRRKQKIAKYLDRFGVPGVCLLGPIVVASQITAPALVALGATKRSVYVWQAVAIVAWGVLFGFFGDLAAGWFM
>CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase
MTRRDPSPHGGKDTAPAPEASVAARQTIRQREIRSFVISIVVMAGAGLVTTTVWWTALVAIPSLALSTALLFRGWDRPPNPLLLAGSGLLGVLALVVTSLTYSNFTGSTGLAITAGVWIAHRPRDRLVLTLLACLGIAALTWATALLSGNSGGVYQLVVMMSITGSVWIVALVESHTQDRLFDLLEREKDHERELSILRERNRFAADLHDIQGHTLHVIKLKAAVAAKLQHTDPERTRQELEVIQRLVADTIGQARQLANSTHALVFSTELSNAVELFRAAGITTRVDRTEDDPGPHEAHFALALREATTNVLRHARPGEVTITSSADTLSVRNDGADIKDAAPLRGLATLADRVRAVGGTLTADRDGGVHTLTVTFPTEAR
>CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator
MTITVLLADDERLIRSALATLLPLEGDIDVVAEAGTGTEAVAAFERLRPDVAVLDLEMPELDGLHAAERILNQAPGQAVLMLTRYARPGTLRSALRLGVRGFLGKDSEASLIASAVAEVAAGGRYVDANISAQALIDDCPLTERERDVLRVAGDGYSVKDMAKILHLAPGTVRNYLSSAIQKTHTNTRHDAARYAREHDWL
>CP025990.1|AUS80826.1|5577912_5578425_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MPDDIQDWNRRIVSEFRSNAGFVRWSTEKDLAEGRPIPPPLPSFDPRQSVPIILVNHIGAVTGRRRTSPLMYQAVRDAFAVFATFGGSPRPPAWYHNIVRNPEVVVEVGSDVTGAIARVVQGEEREDIWVEQARLVPAFADFEKTARRRIPVVVLDPIPSPAAMRAHGAS
>CP025990.1|AUS80825.1|5577477_5577879_-|MerR-family-DNA-binding-transcriptional-regulator
MERMVSAVDQRDWLRIGELARRTATSTRSLRYYEQRGLIVSDREHNGYRRYAPDVVPVVNNIRRLLNAGLSIDDIKQFGSCVRSPSLDATPCAPALEVYEQRLKILRTRIDTLQHLHAALAEQTEHLRAQLPS
>CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS80837.1|5594966_5595785_-|hypothetical-protein
MSDFAERWARAGTGELCWLGASGPTGAAVIPLSREGRPCVALPLSRLAEADDLTGRRVAFCVPGRPGQEGEPAPGMVAVGAVRVEHDLEGAEYVEHLLHQEMVKYPPTRLRADSLLSRRENWWWVARVIVSVDGDPEVRELPPRRDQRDALLVREADAEARAPRVDVVSAGDWAAEPGGELALAEDPNRTPGVGEPAFVFGHHHSPDYERWERWHRAGTLVGNRLRVEHSVGGPVASVRPFGILGRFQGHRALARECRAGMAELERRLDVPC
>CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A
MPAIVVMLAVIAVFAVAYRYYSAYLARRVYVLNPRYVTPAHRYTDGIDFVPTSRHIVFSHHFISVAGAAPIVGPAVGVYWGWGPALVWVVVGSIFAAGVHDFGALVVSVRHRARSIGALAGEVISKRARGLFLLIIFFLLTLVNAVFSVVMANLFIANPASVLPILVEIPLAIAVGQYIYRTRTAALVPSIIALLVVYAMIPLGLLVPISLDPVASALGTDARTLWIIFIFLYAFAASRLPVWMLLQPRDYINQHQLVIALVIILLGMGIGLNRIVAPVVNDVPADSPPWFPLLFVTIACGAISGFHSLVASGTTAKQINKETDARFVGYTSALGEGGLAVCSILACTAGIAATTIEWNALFSDFSTASGGATDNFVNGVANFASNLGIPLEVGVVFAAVVVISFAATTMDTGVRLQRYIVQEIAEIVRFRPLARSLTWSSLVAVVVPLALALAPGDLAFGTLWQLFGTTNQLTAGLALAVIAVWVTKKRRNPLAVLIPLVFLLVMTSWALIINLIDFVQAGEWLLAPLDAVIFVLAIWLIIEASLALRSAWASRGLPPEDDEDEDVDAAAVTSGETTAEQPAGRTPTDTDER
>CP025990.1|AUS81985.1|5597835_5598090_+|hypothetical-protein
MRAGLRAVAEFHEAWFTARWRSTLRREARDQQDTMRALMLLDTLGVDSPVAYETLELVPFLLADMHEWHVRMGRDEYDGPGGCC
>CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase
MLLTRPITFFAGKGGVGKTTMAAAHALASADAGHRTLVISTDPAHSLGDAFETTLGDRPRRLGPTLWAAEPDGDAAVRRRVRQVEDDAAAALPRRIMPAVRRHLGHAATGPGMAESALTDVLTGYLEDVPGEWDRLVVDSAPTGHLLRMIDLPSLLAPWIQGLARQRERVVAADRFAEAVVGDREPERDPLLERLHDRRRRLERAAERLRTDAEVRLVLVPRRMVLAETERAADALVEGGFTLGTLVVNQIPEDVDVSLLRRIEARFATPGAVRCGLAASEPTGLTRLRELAVPTAR
>CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein
MRRRAPLLAVVPLLLTVAATPALAQSSPSAAPQAAMFPATTSVGVHNAYEQSAFPYFADGLDSGAGMLEIDVWTDELFGRWRVSHDLIGQRNNCVGATHADGLRDGPRNQDLPACLRDIRAWQESNPGHRPIVFKVEFKDGFHDRGGLGPAAFDALVADTLGDGVFRPVDLLTRPDGSRFATLDEAALAGNWPSRDTLAGKVVFELIPGTFEQGNPFDDLWTDEEYSRHLRDLAAEGRIEQAQAFPAVLGAEAGDPRERYEDESLRPWFVFFDGNATTYVRPEVDTAWYHERNYVLLMTNSHSVAPAIDANHPTEQEARDRLHLLAGEHASIVSSDWRDPGVLSAVAQRGQG
>CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase
MSTTPSSLTPEDLEFLSRPLHGFLTVAAGPLPPQPRPVWFEATAEGTIQLFTGPDSPKVRRIRRDPRASLVVGSPVGESERWVSVAGRVEVVPDGALELCSRLAARYWDLNDPGRAEELAGMMSDEQVRLVIHPETVRRFPL
>CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase
MRNDTTLVLGATGKTGRRILARLRLRGIPVRAASRSTQPRFDWSDPDDWGAVLEGVDAAYVVAPTVPGPVHEFVAQAEAAGVRRLVLLSGRGADDWGDSTFGLDMLSAEEAVRGSALEWTVLRPSNFAQNFSEDLFHAPLVAGELALPAGAVPDPIIDVEDVADAAVTVLTEPGRHAGGVHELTGPRALTYPEAVDLIARASGRPITYRRISPTEYAATLVEQGLSQDDADHVAEMFVMMERGALASPTEDLAALLGRAPRTFEDYVVRAAAAGAWRP
>CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator
MDAFSDLLRGVRAHGSLVGSSTHTPPWALHFVDGAPLTLCTVLTGGGWIVPEDGAPEPLRARETIIVRGPGTFSFVDEVGTSAEPIPCGELCATPEEGGTRHRRGWHDPGSPEPGRESTTLIVGAYPVRGEISRRLLEALPGVLRVCAGGTGDPVLDHLAAEVAVDAPGQQVVLDRLLDWMLVCTLREWFDRPGGEPPAWWAAQHDAVVGGALRLLHGEPAAPWTVAALAARIGVSRSTLAKRFADLVGEPPLTYLTRWRMTLAADLLAERGSDTLEEIAHAVGYSDAFGFSAAFKRVRGVSPSEFRRAATTLDPAPVGFVPAGTIPVGGHV

Crispr_ID: CP025990_41

• CRISPR_ID: CP025990_41
• CRISPR_location: 5593702-5594585
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 14 spacers
• Cas_protein_info: WYL

Consensus repeat of CP025990_41

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGACGAC	PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCCN	CRT
GGAACAGCCCCGCGTGCGCGGGGACGACGC	PILER-CR

spacers of CP025990_41

>41.1|5593730|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TCCGACCGCCTATGGGTTCCCCCGTGGTGCCCT
>41.2|5593791|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTTCCCACACCAGGTCGGGGCCGGATACGAGAT
>41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
CAGCGCGGCGGCGTCCAGGCGGCGGCCCATCGC
>41.4|5593913|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GGTGGATCAGCCCGCCGACAACAACCCCGCCGA
>41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCAGTCCCGGTCTGCGTCGGCGCTGCCGGCGC
>41.6|5594035|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GCCCGCCCGGCTGCGGGCCTTCTCCCTCGAGAA
>41.7|5594096|34|CP025990|PILER-CR,CRISPRCasFinder,CRT
CGGACTGGCATCACCGACAGAACAGGGGCCGGGG
>41.8|5594158|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
GTGCACACAGGTCTATGTCGGGGGAGCGCGGGT
>41.9|5594219|33|CP025990|PILER-CR,CRISPRCasFinder,CRT
TACCTGTGGCTGCGGCCAACGTGGATCGCCGCC
>41.10|5594280|33|CP025990|CRISPRCasFinder,CRT
CGCTGACATGGCCACGCGGAGTGAAACCGCACC
>41.11|5594341|33|CP025990|CRISPRCasFinder,CRT
CGCGAAAACGGATTCTGGGAAGACACCGACGTT
>41.12|5594402|32|CP025990|CRISPRCasFinder,CRT
TCCCGGGGGTGGTTGCACCCGGGAGTCTGCCG
>41.13|5594462|34|CP025990|CRISPRCasFinder,CRT
CGTCCGGGACGCCCAGGGCGTGATCCGCTCCGGC
>41.14|5594524|34|CP025990|CRISPRCasFinder,CRT
TGGACCACATCGGCCACAAAAATCACTACATAGT
>41.15|5594462|32|CP025990|PILER-CR
CGTCCGGGACGCCCAGGGCGTGATCCGCTCCG
>41.16|5594524|32|CP025990|PILER-CR
TGGACCACATCGGCCACAAAAATCACTACATA

CRISPR arrays and Neighbor proteins around CP025990_41

CRISPR arrays

The CRISPR arrays of CP025990_41

>merge|CP025990|41|5593702-5594585|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCCTCCGACCGCCTATGGGTTCCCCCGTGGTGCCCTGTCGTCCCCGCGCACGCGGGGCTGTTCCGTTCCCACACCAGGTCGGGGCCGGATACGAGATGTCGTCCCCGCGCACGCGGGGCTGTTCCCAGCGCGGCGGCGTCCAGGCGGCGGCCCATCGCGTCGTCCCCGCGCACGCGGGGCTGTTCCGGTGGATCAGCCCGCCGACAACAACCCCGCCGAGTCGTCCCCGCGCACGCGGGGCTGTTCCGCCAGTCCCGGTCTGCGTCGGCGCTGCCGGCGCGTCGTCCCCGCGCACGCGGGGCTGTTCCGCCCGCCCGGCTGCGGGCCTTCTCCCTCGAGAAGTCGTCCCCGCGCACGCGGGGCTGTTCCCGGACTGGCATCACCGACAGAACAGGGGCCGGGGGTCGTCCCCGCGCACGCGGGGCTGTTCCGTGCACACAGGTCTATGTCGGGGGAGCGCGGGTGTCGTCCCCGCGCACGCGGGGCTGTTCCTACCTGTGGCTGCGGCCAACGTGGATCGCCGCCGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCTGACATGGCCACGCGGAGTGAAACCGCACCGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCGAAAACGGATTCTGGGAAGACACCGACGTTGTCGTCCCCGCGCAACGGGGCTGTTCCGTCCCGGGGGTGGTTGCACCCGGGAGTCTGCCGGTCGTCCCCGCGCACGCGGGGCTGTTCCCGTCCGGGACGCCCAGGGCGTGATCCGCTCCGGCGTCGTCCCCGCGCACGCGGGGCTGTTCCTGGACCACATCGGCCACAAAAATCACTACATAGTGTCGTCCCCGCGCACGCGGGGCTGCTCC

>CP025990|41|33|5593702-5594279|PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TCCGACCGCCTATGGGTTCCCCCGTGGTGCCCT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTTCCCACACCAGGTCGGGGCCGGATACGAGAT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CAGCGCGGCGGCGTCCAGGCGGCGGCCCATCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGTGGATCAGCCCGCCGACAACAACCCCGCCGA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCAGTCCCGGTCTGCGTCGGCGCTGCCGGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCGCCCGGCTGCGGGCCTTCTCCCTCGAGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGACTGGCATCACCGACAGAACAGGGGCCGGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTGCACACAGGTCTATGTCGGGGGAGCGCGGGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TACCTGTGGCTGCGGCCAACGTGGATCGCCGCC
GTCGTCCCCGCGCACGCGGGGCTGTTCCCGCTGACATGGCCACGCGGAGTGAAACCGCACCGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCGAAAACGGATTCTGGGAAGACACCGACGTTGTCGTCCCCGCGCAACGGGGCTGTTCCGTCCCGGGGGTGGTTGCACCCGGGAGTCTGCCGGTCGTCCCCGCGCACGCGGGGCTGTTCC	CGTCCGGGACGCCCAGGGCGTGATCCGCTCCG
GCGTCGTCCCCGCGCACGCGGGGCTGTTCC	TGGACCACATCGGCCACAAAAATCACTACATA


>CP025990|41|39|5593702-5594585|CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TCCGACCGCCTATGGGTTCCCCCGTGGTGCCCT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTTCCCACACCAGGTCGGGGCCGGATACGAGAT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CAGCGCGGCGGCGTCCAGGCGGCGGCCCATCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGTGGATCAGCCCGCCGACAACAACCCCGCCGA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCAGTCCCGGTCTGCGTCGGCGCTGCCGGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCGCCCGGCTGCGGGCCTTCTCCCTCGAGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGACTGGCATCACCGACAGAACAGGGGCCGGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTGCACACAGGTCTATGTCGGGGGAGCGCGGGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TACCTGTGGCTGCGGCCAACGTGGATCGCCGCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCTGACATGGCCACGCGGAGTGAAACCGCACC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCGAAAACGGATTCTGGGAAGACACCGACGTT
GTCGTCCCCGCGCAACGGGGCTGTTCCG	TCCCGGGGGTGGTTGCACCCGGGAGTCTGCCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGTCCGGGACGCCCAGGGCGTGATCCGCTCCGGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TGGACCACATCGGCCACAAAAATCACTACATAGT
GTCGTCCCCGCGCACGCGGGGCTGCTCC

>CP025990|41|32|5593702-5594585|CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TCCGACCGCCTATGGGTTCCCCCGTGGTGCCCT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTTCCCACACCAGGTCGGGGCCGGATACGAGAT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CAGCGCGGCGGCGTCCAGGCGGCGGCCCATCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGTGGATCAGCCCGCCGACAACAACCCCGCCGA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCAGTCCCGGTCTGCGTCGGCGCTGCCGGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCGCCCGGCTGCGGGCCTTCTCCCTCGAGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGACTGGCATCACCGACAGAACAGGGGCCGGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTGCACACAGGTCTATGTCGGGGGAGCGCGGGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TACCTGTGGCTGCGGCCAACGTGGATCGCCGCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCTGACATGGCCACGCGGAGTGAAACCGCACC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCGAAAACGGATTCTGGGAAGACACCGACGTT
GTCGTCCCCGCGCAACGGGGCTGTTCCG	TCCCGGGGGTGGTTGCACCCGGGAGTCTGCCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGTCCGGGACGCCCAGGGCGTGATCCGCTCCGGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TGGACCACATCGGCCACAAAAATCACTACATAGT
GTCGTCCCCGCGCACGCGGGGCTGCTCC

>CP025990|41|34|5594432-5594585|PILER-CR
	TCCGACCGCCTATGGGTTCCCCCGTGGTGCCCT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTTCCCACACCAGGTCGGGGCCGGATACGAGAT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CAGCGCGGCGGCGTCCAGGCGGCGGCCCATCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGTGGATCAGCCCGCCGACAACAACCCCGCCGA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCAGTCCCGGTCTGCGTCGGCGCTGCCGGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCCCGCCCGGCTGCGGGCCTTCTCCCTCGAGAA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGACTGGCATCACCGACAGAACAGGGGCCGGGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTGCACACAGGTCTATGTCGGGGGAGCGCGGGT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	TACCTGTGGCTGCGGCCAACGTGGATCGCCGCC
GTCGTCCCCGCGCACGCGGGGCTGTTCCCGCTGACATGGCCACGCGGAGTGAAACCGCACCGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCGAAAACGGATTCTGGGAAGACACCGACGTTGTCGTCCCCGCGCAACGGGGCTGTTCCGTCCCGGGGGTGGTTGCACCCGGGAGTCTGCCGGTCGTCCCCGCGCACGCGGGGCTGTTCC	CGTCCGGGACGCCCAGGGCGTGATCCGCTCCG
GCGTCGTCCCCGCGCACGCGGGGCTGTTCC	TGGACCACATCGGCCACAAAAATCACTACATA
GTGTCGTCCCCGCGCACGCGGGGCTGCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|334450
CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187578
CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS81985.1|5597835_5598090_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80844.1|5603997_5604348_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B	unknown	unknown	gnl|CDD|235501
CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein	unknown	unknown	gnl|CDD|176531
CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378976
CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase	unknown	unknown	gnl|CDD|376527
CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|224877
CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
CP025990.1|AUS80843.1|5603721_5603964_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80837.1|5594966_5595785_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80829.1|5581129_5581642_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase	unknown	unknown	gnl|CDD|223082

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	1.5e-34	114.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.47506e-12
CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	2.37513e-13
CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.54865e-62
CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.1672e-25
CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B	gnl|CDD|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein	gnl|CDD|176531	cd08589, PI-PLCc_SaPLC1_like, Catalytic domain of Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1-like proteins. This subfamily corresponds to the catalytic domain present in Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1 (SaPLC1) and similar proteins. The typical bacterial phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) catalyzes Ca2+-independent hydrolysis of the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). The catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. In contrast, SaPLC1 is the first known natural Ca2+-dependent bacterial PI-PLC. It is more closely related to the eukaryotic PI-PLCs rather than the typical bacterial PI-PLCs. It participates in PI metabolism to generate myo-inositol-1-phosphate and myo-inositol-1:2-cyclic phosphate simultaneously. SaPLC1 and other members in this subfamily have two Ca2+-chelating amino acid substitutions which convert them from metal-independent enzymes to metal-dependent bacterial PI-PLC. Additionally, SaPLC1 active site utilizes a mechanism of amino acid juxtaposition, swapping amino acid positions, to adapt a calcium binding pocket and maintain more ideal active site geometry to support efficient catalysis.	1.59541e-77
CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	8.41336e-58
CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	5.85638e-41
CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase	gnl|CDD|376527	pfam01326, PPDK_N, Pyruvate phosphate dikinase, PEP/pyruvate binding domain. This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP).	3.18964e-96
CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A	gnl|CDD|224877	COG1966, CstA, Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms].	4.0558e-146
CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.10376e-56
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.3125e-27

Protein sequences

>CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator
MADVTQRSLALLAALRNGQPVSGEELARLLEVDQRTIRRDVERLRGYGYEVDAQPGPGGYYRMPGGNTVPPIPGAVAGADGPPAAEAADHALSENGGEPLAATGRRALDQLTQHPATRTTEHCLPGDVDAAGEPGWRTGTGGDSADLVGAALQRCRVLTFDYTDAAGVVSTRRVEPHRRMHQLMRWYLLAWDAGRRDWRVFRMDRISEPRVEEASFAPRPLPPDDGVGYPHWTTHRSPLRVVVTVEAPVAAVADVLRHQQVEFLAVRPDRTRAVLAVESWQWLVLNLAFLDVEFTVEEPEEVRSACASFASRLGLASTSAPVAP
>CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase
MRSPLVDNEVTHPFVLPLGAGGADLALVGGKGASLDRLVSAGLPVPAGFHVTTTAYRAAHGDHPRPPRRPGTGAGLAEPGATRAGTADPGPWPVPPEVADAVTAAYRELGPDAPPVAVRSSATAEDLPELSFAGQQDTFLNVRGERDLLHALTRCWASLWTPRAVAYRERHDVDPATVAMAVVVQLLVPARAAGVLFTANPLTGSRDELVINASWGLGESVVSGQVNPDTVIVDQRTGRTSHHTTSAKTVRTVPADGGVREEAVDDHLVHAPVLTEQDITRLADLGRRVDALHERPSDVEWALDDSGTPHLLQARPITGLPAPRLPATGQHTTPARPPSSAPPEDTTTRTPAEGRPPATSPPRPRHHRGSGTASRREEWNDSRLGDYLWTNGNLGEAIPSVMTPATWSFVQVFMLRTMGIPSCQGHPTWGNIGGRFYLNLSTSLSLGTAFGRTVDQMADTVSAVFGRIPPGTPVPVIPLRRWATLRELVPLVTAFRLRLRIAHRRLASYLDTAADRCAALRARARTAPTPDALLRLWRTELWPYCLETFDMMSAAARGRGGGNRLVKVRQRLAEQVGEADANALTTGIAHGAPLASLGPLLGLASVANGDTSPEDHIRQWGHRCPDEFEISLPRPAEDPTWLDHQLAAFRDSRTDVHAMLTQRRAEHEQAWARYQRDHPRHVTRTRRELRSWARLVHDREATRSEVNRAFWAIREVVLRAGELTGHGHDLFLLERHEIERVLAGDDRPLAAVPARRDAYERYRALPNYPTLIRGPFDPERWAADPRRRTDLYDAATAPSSPEHPEPANHHSRTAGAPRPAATTPEPERKPAPNPITGFPGAVGTVEGVARVVTSVDDAQDLRAGEVLVTTATNVGWTPLFPRAAAVVTDVGAPLSHAAIVARELGIPAVVGCGNATMRIRTGDRLRVHGERGEVHLIDPPTEGGAPPTGA
>CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator
MVIRFGGVRVASDERDDAAASGDTRRDRAGRILDAASALTLRWGYQKTTIDDIARAAGVAKGTIYLHWKSRDALFLALLRRERALAATEIRDLAAQDPAGHTLRGVLVHSYRVVARRPLLLAVLTRDRDVLGRLLTTGAPTARPPLSVGFPRYLEHLRAGGWVRTDQTLAAQLSLGTATIYGFLLTRPLMPDEFAVTDDDAAELVADTVCRALDRGSPLGDTETEGVAAASAAYLAEAARFTIERYENEVA
>CP025990.1|AUS80831.1|5584361_5586425_-|type-IIA-DNA-topoisomerase-subunit-B
MTASAETIYGADDLTHLEGLEAVRKRPGMYIGSTDSRGINHLFSEVVDNSTDEGVAGYATRIVVTLHADGSVQVDDDGRGIPTGVHAKSGISGVELVLTRLHAGGKFGGSGYKTSGGLHGVGASAVNALSHRFDVTVRRDGLVHQMSFAHGAPGVFDGPGARAKFTPRSGLHVTGKMKRDETTGTSIRYWHDARYFETGAALDVEGVRSKLRNTAFLVPGVTYVLRTATEDSISEETFHFPNGLPDMVDFLAPTGDRAVSGTLVVSGEGTYKENAADENGVMQSNVPRRAEVEVAFRWGTGYERTVECFTNTIRNVHGGTHRKGFERAAVKALHAAIARTRGLLRAKEEPPTLEDVLEGMTAVIHVRIPEPQFTSQTKDELSTAGITKVVQAVVEAHLREWTEDRRTKVEAKTVLQKIVDASRVRLTQKQQKDAARRKTALEGAAMPAKLVDCRTTGVARSELFLVEGDSALGSARLARVSEYQALLPLRGKILNVQKASLADTLRNAEIASIVQVLGAGSGRTFDLSAMRYGRVILMADADVDGSHIRTLLITLFAKYLRPVIEDGRLYAAMPPLHKITTRGRKPQTHFTFTQREMESTVARLEKAGKQVVTPVPRFKGLGEMDADELWETTMNPATRSVRRITLAEADAAAADEALDLLMGEKVEPRRAWLVRSAARVDRAAIDV
>CP025990.1|AUS80830.1|5581804_5584282_-|DNA-topoisomerase-IV-subunit-A
MARRKGSAQTKVDPTAFDQPGRHVVDNPVHTEIEDSYLEYAYSVIHSRALPDARDGLKPVHRRILFSMHEQGYRPTHAYVKSSRVVGDVMGKYHPHGDTAIYDAMVRLAQDFSMNVPLVDGHGNFGSPDDGPAASRYTEARMSPAALQLVAELGEDTVDFRPNYDGSLEEPAALPAAFPNLLVNGTSGIAVGMATNMIPHNLGEVVAAARWLIRHPDAPLDKLMEFVPGPDLPTGGMLLGLDEVRKAYETGRGVVRMRAKVETGPLPGSRGRQAITVTELPYGVGPEKIIEKITDEVNKSKRLTGVADVKDLTDRENGTRLVIECKVGVNPQALLADLYRLTPLEQSFGINNLVLVDGEPRTLGLKELLEVFLAHRFEVVRRRTTFRRRKRSDRLHLVEGLIRALVDIDRVIRLIRESDDAKAAKEGLIARFDLSEIQATYILDTPLRRLTKYDKVELEEERERLTGEIAELSRILDDEAVLRRLVSTELGRIAKEFPTERRTTLIDGDLKEVLAASKPAGPLEIADDPCQVILSATGLVSRTAAASEEAAEARRRNGRVRHDAVAAVVDSTARGQVVLVTSHGRGIKTDVLPLPVLPQQSGIVSLRGGMPVRELVSLAPGERVLGLAPLGDQIGDSPGLALGTRQGVVKVCSPEWPVRADEFELIALREGDEVVGVTWLADGQESLVFVSSDAALLRYSATLVRPQGLRGGGMAGINVKGDARVVFFGAVAEDGEPVVITATGETVKVTPFGEYPAKGRATAGVRAQRFLATESELSTAWVGARPAPSTGNGTPVELPDPDERRDGTGAPAEIPVVVGYLLERD
>CP025990.1|AUS80829.1|5581129_5581642_+|hypothetical-protein
MESNFITDLFAQLAEFAAGAETWQQVGVLLIAGAIPFIESYLGSFLGVLVGVPAGLAVPAAILGNVIVTFALIALASKARVAATRRRGNGGGGGADAPRRKQKIAKYLDRFGVPGVCLLGPIVVASQITAPALVALGATKRSVYVWQAVAIVAWGVLFGFFGDLAAGWFM
>CP025990.1|AUS80828.1|5579572_5580721_-|two-component-sensor-histidine-kinase
MTRRDPSPHGGKDTAPAPEASVAARQTIRQREIRSFVISIVVMAGAGLVTTTVWWTALVAIPSLALSTALLFRGWDRPPNPLLLAGSGLLGVLALVVTSLTYSNFTGSTGLAITAGVWIAHRPRDRLVLTLLACLGIAALTWATALLSGNSGGVYQLVVMMSITGSVWIVALVESHTQDRLFDLLEREKDHERELSILRERNRFAADLHDIQGHTLHVIKLKAAVAAKLQHTDPERTRQELEVIQRLVADTIGQARQLANSTHALVFSTELSNAVELFRAAGITTRVDRTEDDPGPHEAHFALALREATTNVLRHARPGEVTITSSADTLSVRNDGADIKDAAPLRGLATLADRVRAVGGTLTADRDGGVHTLTVTFPTEAR
>CP025990.1|AUS80827.1|5578970_5579576_-|DNA-binding-response-regulator
MTITVLLADDERLIRSALATLLPLEGDIDVVAEAGTGTEAVAAFERLRPDVAVLDLEMPELDGLHAAERILNQAPGQAVLMLTRYARPGTLRSALRLGVRGFLGKDSEASLIASAVAEVAAGGRYVDANISAQALIDDCPLTERERDVLRVAGDGYSVKDMAKILHLAPGTVRNYLSSAIQKTHTNTRHDAARYAREHDWL
>CP025990.1|AUS80837.1|5594966_5595785_-|hypothetical-protein
MSDFAERWARAGTGELCWLGASGPTGAAVIPLSREGRPCVALPLSRLAEADDLTGRRVAFCVPGRPGQEGEPAPGMVAVGAVRVEHDLEGAEYVEHLLHQEMVKYPPTRLRADSLLSRRENWWWVARVIVSVDGDPEVRELPPRRDQRDALLVREADAEARAPRVDVVSAGDWAAEPGGELALAEDPNRTPGVGEPAFVFGHHHSPDYERWERWHRAGTLVGNRLRVEHSVGGPVASVRPFGILGRFQGHRALARECRAGMAELERRLDVPC
>CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A
MPAIVVMLAVIAVFAVAYRYYSAYLARRVYVLNPRYVTPAHRYTDGIDFVPTSRHIVFSHHFISVAGAAPIVGPAVGVYWGWGPALVWVVVGSIFAAGVHDFGALVVSVRHRARSIGALAGEVISKRARGLFLLIIFFLLTLVNAVFSVVMANLFIANPASVLPILVEIPLAIAVGQYIYRTRTAALVPSIIALLVVYAMIPLGLLVPISLDPVASALGTDARTLWIIFIFLYAFAASRLPVWMLLQPRDYINQHQLVIALVIILLGMGIGLNRIVAPVVNDVPADSPPWFPLLFVTIACGAISGFHSLVASGTTAKQINKETDARFVGYTSALGEGGLAVCSILACTAGIAATTIEWNALFSDFSTASGGATDNFVNGVANFASNLGIPLEVGVVFAAVVVISFAATTMDTGVRLQRYIVQEIAEIVRFRPLARSLTWSSLVAVVVPLALALAPGDLAFGTLWQLFGTTNQLTAGLALAVIAVWVTKKRRNPLAVLIPLVFLLVMTSWALIINLIDFVQAGEWLLAPLDAVIFVLAIWLIIEASLALRSAWASRGLPPEDDEDEDVDAAAVTSGETTAEQPAGRTPTDTDER
>CP025990.1|AUS81985.1|5597835_5598090_+|hypothetical-protein
MRAGLRAVAEFHEAWFTARWRSTLRREARDQQDTMRALMLLDTLGVDSPVAYETLELVPFLLADMHEWHVRMGRDEYDGPGGCC
>CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase
MLLTRPITFFAGKGGVGKTTMAAAHALASADAGHRTLVISTDPAHSLGDAFETTLGDRPRRLGPTLWAAEPDGDAAVRRRVRQVEDDAAAALPRRIMPAVRRHLGHAATGPGMAESALTDVLTGYLEDVPGEWDRLVVDSAPTGHLLRMIDLPSLLAPWIQGLARQRERVVAADRFAEAVVGDREPERDPLLERLHDRRRRLERAAERLRTDAEVRLVLVPRRMVLAETERAADALVEGGFTLGTLVVNQIPEDVDVSLLRRIEARFATPGAVRCGLAASEPTGLTRLRELAVPTAR
>CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein
MRRRAPLLAVVPLLLTVAATPALAQSSPSAAPQAAMFPATTSVGVHNAYEQSAFPYFADGLDSGAGMLEIDVWTDELFGRWRVSHDLIGQRNNCVGATHADGLRDGPRNQDLPACLRDIRAWQESNPGHRPIVFKVEFKDGFHDRGGLGPAAFDALVADTLGDGVFRPVDLLTRPDGSRFATLDEAALAGNWPSRDTLAGKVVFELIPGTFEQGNPFDDLWTDEEYSRHLRDLAAEGRIEQAQAFPAVLGAEAGDPRERYEDESLRPWFVFFDGNATTYVRPEVDTAWYHERNYVLLMTNSHSVAPAIDANHPTEQEARDRLHLLAGEHASIVSSDWRDPGVLSAVAQRGQG
>CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase
MSTTPSSLTPEDLEFLSRPLHGFLTVAAGPLPPQPRPVWFEATAEGTIQLFTGPDSPKVRRIRRDPRASLVVGSPVGESERWVSVAGRVEVVPDGALELCSRLAARYWDLNDPGRAEELAGMMSDEQVRLVIHPETVRRFPL
>CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase
MRNDTTLVLGATGKTGRRILARLRLRGIPVRAASRSTQPRFDWSDPDDWGAVLEGVDAAYVVAPTVPGPVHEFVAQAEAAGVRRLVLLSGRGADDWGDSTFGLDMLSAEEAVRGSALEWTVLRPSNFAQNFSEDLFHAPLVAGELALPAGAVPDPIIDVEDVADAAVTVLTEPGRHAGGVHELTGPRALTYPEAVDLIARASGRPITYRRISPTEYAATLVEQGLSQDDADHVAEMFVMMERGALASPTEDLAALLGRAPRTFEDYVVRAAAAGAWRP
>CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator
MDAFSDLLRGVRAHGSLVGSSTHTPPWALHFVDGAPLTLCTVLTGGGWIVPEDGAPEPLRARETIIVRGPGTFSFVDEVGTSAEPIPCGELCATPEEGGTRHRRGWHDPGSPEPGRESTTLIVGAYPVRGEISRRLLEALPGVLRVCAGGTGDPVLDHLAAEVAVDAPGQQVVLDRLLDWMLVCTLREWFDRPGGEPPAWWAAQHDAVVGGALRLLHGEPAAPWTVAALAARIGVSRSTLAKRFADLVGEPPLTYLTRWRMTLAADLLAERGSDTLEEIAHAVGYSDAFGFSAAFKRVRGVSPSEFRRAATTLDPAPVGFVPAGTIPVGGHV
>CP025990.1|AUS80843.1|5603721_5603964_-|hypothetical-protein
MFRAGHHAGRTRPGTGAATARGALAEVHAQTAGRTTEALRAYLLDPRHAQRLAAGLAAAWRARFGGRGMAAPPPVWPRTG
>CP025990.1|AUS80844.1|5603997_5604348_+|hypothetical-protein
MIRSSRRTRLTRTNQAAVSRNRSAAACSGAVTNAAPSSVTTGPAHSGWSAGRITSGSSTSFTVRLSGPPRGPLNASTPWRPRHTSSSTAALGRRPSISWRLSLLVGVPSPVGMAPG

Crispr_ID: CP025990_42

• CRISPR_ID: CP025990_42
• CRISPR_location: 5600546-5600880
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: WYL

Consensus repeat of CP025990_42

Consensus_repeat	Method
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRT
GGAACAGCCCCGCGTGCGCGGGGACGACC	PILER-CR

spacers of CP025990_42

>42.1|5600574|33|CP025990|CRISPRCasFinder,CRT
CTCACCCAACAGGGGGACTCGTGTATCAGCCTG
>42.2|5600635|33|CP025990|CRISPRCasFinder,CRT
CTCGACCTCGGCTGCGGGGAGATCGGCCTCCCG
>42.3|5600696|34|CP025990|CRISPRCasFinder,CRT
AGCGGCCCGGTCGGAGCTGCACACTCCGGACCGG
>42.4|5600758|34|CP025990|CRISPRCasFinder,CRT
CGGTTCCGGCCCTCCACTCAGGCCGGCCTCGCCG
>42.5|5600820|33|CP025990|CRISPRCasFinder,CRT
GATGGCCCAAATGCTGGACGTTCCGCCTAGGGC
>42.6|5600696|33|CP025990|PILER-CR
AGCGGCCCGGTCGGAGCTGCACACTCCGGACCG
>42.7|5600758|33|CP025990|PILER-CR
CGGTTCCGGCCCTCCACTCAGGCCGGCCTCGCC
>42.8|5600820|32|CP025990|PILER-CR
GATGGCCCAAATGCTGGACGTTCCGCCTAGGG

CRISPR arrays and Neighbor proteins around CP025990_42

CRISPR arrays

The CRISPR arrays of CP025990_42

>merge|CP025990|42|5600546-5600880|CRISPRCasFinder,CRT,PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCCCTCACCCAACAGGGGGACTCGTGTATCAGCCTGGTCGTCCCCGCGCACGCGGGGCTGTTCCCTCGACCTCGGCTGCGGGGAGATCGGCCTCCCGGTCGTCCCCGCGCACGCGGGGCTGTTCCAGCGGCCCGGTCGGAGCTGCACACTCCGGACCGGGTCGTCCCCGCGCACGCGGGGCTGTTCCCGGTTCCGGCCCTCCACTCAGGCCGGCCTCGCCGGTCGTCCCCGCGCACGCGGGGCTGTTCCGATGGCCCAAATGCTGGACGTTCCGCCTAGGGCGTCGTCCCCGCGTACGCGGGGCTGTTCC

>CP025990|42|40|5600546-5600880|CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CTCACCCAACAGGGGGACTCGTGTATCAGCCTG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CTCGACCTCGGCTGCGGGGAGATCGGCCTCCCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	AGCGGCCCGGTCGGAGCTGCACACTCCGGACCGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGTTCCGGCCCTCCACTCAGGCCGGCCTCGCCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GATGGCCCAAATGCTGGACGTTCCGCCTAGGGC
GTCGTCCCCGCGTACGCGGGGCTGTTCC

>CP025990|42|33|5600546-5600880|CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CTCACCCAACAGGGGGACTCGTGTATCAGCCTG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CTCGACCTCGGCTGCGGGGAGATCGGCCTCCCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	AGCGGCCCGGTCGGAGCTGCACACTCCGGACCGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGTTCCGGCCCTCCACTCAGGCCGGCCTCGCCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GATGGCCCAAATGCTGGACGTTCCGCCTAGGGC
GTCGTCCCCGCGTACGCGGGGCTGTTCC

>CP025990|42|35|5600667-5600880|PILER-CR
GGTCGTCCCCGCGCACGCGGGGCTGTTCC	AGCGGCCCGGTCGGAGCTGCACACTCCGGACCG
GGTCGTCCCCGCGCACGCGGGGCTGTTCC	CGGTTCCGGCCCTCCACTCAGGCCGGCCTCGCC
GGTCGTCCCCGCGCACGCGGGGCTGTTCC	GATGGCCCAAATGCTGGACGTTCCGCCTAGGG
CGTCGTCCCCGCGTACGCGGGGCTGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS80846.1|5607171_5608182_+|ribose-ABC-transporter-permease	unknown	unknown	gnl|CDD|224093
CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|334450
CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187578
CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein	unknown	unknown	gnl|CDD|366690
CP025990.1|AUS80844.1|5603997_5604348_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80845.1|5605534_5607175_+|D-xylose-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein	unknown	unknown	gnl|CDD|176531
CP025990.1|AUS81985.1|5597835_5598090_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80848.1|5609646_5611284_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase	unknown	unknown	gnl|CDD|223082
CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378976
CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase	unknown	unknown	gnl|CDD|376527
CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|224877
CP025990.1|AUS81987.1|5604444_5605242_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80843.1|5603721_5603964_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80837.1|5594966_5595785_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS80847.1|5608227_5609181_+|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380660
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	1.5e-34	114.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.47506e-12
CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.12912e-79
CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	5.85638e-41
CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.54865e-62
CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000214066
CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein	gnl|CDD|176531	cd08589, PI-PLCc_SaPLC1_like, Catalytic domain of Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1-like proteins. This subfamily corresponds to the catalytic domain present in Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1 (SaPLC1) and similar proteins. The typical bacterial phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) catalyzes Ca2+-independent hydrolysis of the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). The catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. In contrast, SaPLC1 is the first known natural Ca2+-dependent bacterial PI-PLC. It is more closely related to the eukaryotic PI-PLCs rather than the typical bacterial PI-PLCs. It participates in PI metabolism to generate myo-inositol-1-phosphate and myo-inositol-1:2-cyclic phosphate simultaneously. SaPLC1 and other members in this subfamily have two Ca2+-chelating amino acid substitutions which convert them from metal-independent enzymes to metal-dependent bacterial PI-PLC. Additionally, SaPLC1 active site utilizes a mechanism of amino acid juxtaposition, swapping amino acid positions, to adapt a calcium binding pocket and maintain more ideal active site geometry to support efficient catalysis.	1.59541e-77
CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	8.41336e-58
CP025990.1|AUS80846.1|5607171_5608182_+|ribose-ABC-transporter-permease	gnl|CDD|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.01803e-85
CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase	gnl|CDD|376527	pfam01326, PPDK_N, Pyruvate phosphate dikinase, PEP/pyruvate binding domain. This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP).	3.18964e-96
CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A	gnl|CDD|224877	COG1966, CstA, Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms].	4.0558e-146
CP025990.1|AUS80845.1|5605534_5607175_+|D-xylose-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.3125e-27
CP025990.1|AUS80847.1|5608227_5609181_+|BMP-family-ABC-transporter-substrate-binding-protein	gnl|CDD|380660	cd20005, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate-binding protein such as CUT2. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	2.99143e-123
CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	2.37513e-13

Protein sequences

>CP025990.1|AUS80840.1|5599110_5600169_-|hypothetical-protein
MRRRAPLLAVVPLLLTVAATPALAQSSPSAAPQAAMFPATTSVGVHNAYEQSAFPYFADGLDSGAGMLEIDVWTDELFGRWRVSHDLIGQRNNCVGATHADGLRDGPRNQDLPACLRDIRAWQESNPGHRPIVFKVEFKDGFHDRGGLGPAAFDALVADTLGDGVFRPVDLLTRPDGSRFATLDEAALAGNWPSRDTLAGKVVFELIPGTFEQGNPFDDLWTDEEYSRHLRDLAAEGRIEQAQAFPAVLGAEAGDPRERYEDESLRPWFVFFDGNATTYVRPEVDTAWYHERNYVLLMTNSHSVAPAIDANHPTEQEARDRLHLLAGEHASIVSSDWRDPGVLSAVAQRGQG
>CP025990.1|AUS80839.1|5598080_5598974_+|arsenic-transporting-ATPase
MLLTRPITFFAGKGGVGKTTMAAAHALASADAGHRTLVISTDPAHSLGDAFETTLGDRPRRLGPTLWAAEPDGDAAVRRRVRQVEDDAAAALPRRIMPAVRRHLGHAATGPGMAESALTDVLTGYLEDVPGEWDRLVVDSAPTGHLLRMIDLPSLLAPWIQGLARQRERVVAADRFAEAVVGDREPERDPLLERLHDRRRRLERAAERLRTDAEVRLVLVPRRMVLAETERAADALVEGGFTLGTLVVNQIPEDVDVSLLRRIEARFATPGAVRCGLAASEPTGLTRLRELAVPTAR
>CP025990.1|AUS81985.1|5597835_5598090_+|hypothetical-protein
MRAGLRAVAEFHEAWFTARWRSTLRREARDQQDTMRALMLLDTLGVDSPVAYETLELVPFLLADMHEWHVRMGRDEYDGPGGCC
>CP025990.1|AUS80838.1|5595946_5597728_+|carbon-starvation-protein-A
MPAIVVMLAVIAVFAVAYRYYSAYLARRVYVLNPRYVTPAHRYTDGIDFVPTSRHIVFSHHFISVAGAAPIVGPAVGVYWGWGPALVWVVVGSIFAAGVHDFGALVVSVRHRARSIGALAGEVISKRARGLFLLIIFFLLTLVNAVFSVVMANLFIANPASVLPILVEIPLAIAVGQYIYRTRTAALVPSIIALLVVYAMIPLGLLVPISLDPVASALGTDARTLWIIFIFLYAFAASRLPVWMLLQPRDYINQHQLVIALVIILLGMGIGLNRIVAPVVNDVPADSPPWFPLLFVTIACGAISGFHSLVASGTTAKQINKETDARFVGYTSALGEGGLAVCSILACTAGIAATTIEWNALFSDFSTASGGATDNFVNGVANFASNLGIPLEVGVVFAAVVVISFAATTMDTGVRLQRYIVQEIAEIVRFRPLARSLTWSSLVAVVVPLALALAPGDLAFGTLWQLFGTTNQLTAGLALAVIAVWVTKKRRNPLAVLIPLVFLLVMTSWALIINLIDFVQAGEWLLAPLDAVIFVLAIWLIIEASLALRSAWASRGLPPEDDEDEDVDAAAVTSGETTAEQPAGRTPTDTDER
>CP025990.1|AUS80837.1|5594966_5595785_-|hypothetical-protein
MSDFAERWARAGTGELCWLGASGPTGAAVIPLSREGRPCVALPLSRLAEADDLTGRRVAFCVPGRPGQEGEPAPGMVAVGAVRVEHDLEGAEYVEHLLHQEMVKYPPTRLRADSLLSRRENWWWVARVIVSVDGDPEVRELPPRRDQRDALLVREADAEARAPRVDVVSAGDWAAEPGGELALAEDPNRTPGVGEPAFVFGHHHSPDYERWERWHRAGTLVGNRLRVEHSVGGPVASVRPFGILGRFQGHRALARECRAGMAELERRLDVPC
>CP025990.1|AUS80836.1|5593300_5593642_-|hypothetical-protein
MRSMGSAKKYPQELRRRAVEMVRELEGQWGPGRGAIARVADQLGVHPEALRYWVRSGEPSTHTGSADSTNTGESDRDRIARLERENAELRRSNEILKAASAFFAREMDPRPPS
>CP025990.1|AUS80835.1|5592413_5593265_-|IS3-family-transposase
MEVSCRTVGLSVSTYYAIRNRRTNPSARHRRDRELVAVIRRIWEDSHRLYGARKVWAALHRQGVTVGRCTVERLMRSEAMTGLVTRSRRPRSMLPGQVEGQPGDLVERVFRAPRPNRLWVTDLTYVRLGESRFVYSALVVDAFSRAIVGWQVSDTADTSLALDALDMALWARRSRLSPGLVAHSDRGVQYTALRYSQRLSRSGIARSVGRRGDSYDNALAESVNALYKKELIYRKGPWKGVADVRAATAEWIHWYNHHRLHSWCGNRPPLEYEERHWRQATAV
>CP025990.1|AUS80834.1|5590564_5591539_-|transcriptional-regulator
MADVTQRSLALLAALRNGQPVSGEELARLLEVDQRTIRRDVERLRGYGYEVDAQPGPGGYYRMPGGNTVPPIPGAVAGADGPPAAEAADHALSENGGEPLAATGRRALDQLTQHPATRTTEHCLPGDVDAAGEPGWRTGTGGDSADLVGAALQRCRVLTFDYTDAAGVVSTRRVEPHRRMHQLMRWYLLAWDAGRRDWRVFRMDRISEPRVEEASFAPRPLPPDDGVGYPHWTTHRSPLRVVVTVEAPVAAVADVLRHQQVEFLAVRPDRTRAVLAVESWQWLVLNLAFLDVEFTVEEPEEVRSACASFASRLGLASTSAPVAP
>CP025990.1|AUS80833.1|5587541_5590394_+|pyruvate,-phosphate-dikinase
MRSPLVDNEVTHPFVLPLGAGGADLALVGGKGASLDRLVSAGLPVPAGFHVTTTAYRAAHGDHPRPPRRPGTGAGLAEPGATRAGTADPGPWPVPPEVADAVTAAYRELGPDAPPVAVRSSATAEDLPELSFAGQQDTFLNVRGERDLLHALTRCWASLWTPRAVAYRERHDVDPATVAMAVVVQLLVPARAAGVLFTANPLTGSRDELVINASWGLGESVVSGQVNPDTVIVDQRTGRTSHHTTSAKTVRTVPADGGVREEAVDDHLVHAPVLTEQDITRLADLGRRVDALHERPSDVEWALDDSGTPHLLQARPITGLPAPRLPATGQHTTPARPPSSAPPEDTTTRTPAEGRPPATSPPRPRHHRGSGTASRREEWNDSRLGDYLWTNGNLGEAIPSVMTPATWSFVQVFMLRTMGIPSCQGHPTWGNIGGRFYLNLSTSLSLGTAFGRTVDQMADTVSAVFGRIPPGTPVPVIPLRRWATLRELVPLVTAFRLRLRIAHRRLASYLDTAADRCAALRARARTAPTPDALLRLWRTELWPYCLETFDMMSAAARGRGGGNRLVKVRQRLAEQVGEADANALTTGIAHGAPLASLGPLLGLASVANGDTSPEDHIRQWGHRCPDEFEISLPRPAEDPTWLDHQLAAFRDSRTDVHAMLTQRRAEHEQAWARYQRDHPRHVTRTRRELRSWARLVHDREATRSEVNRAFWAIREVVLRAGELTGHGHDLFLLERHEIERVLAGDDRPLAAVPARRDAYERYRALPNYPTLIRGPFDPERWAADPRRRTDLYDAATAPSSPEHPEPANHHSRTAGAPRPAATTPEPERKPAPNPITGFPGAVGTVEGVARVVTSVDDAQDLRAGEVLVTTATNVGWTPLFPRAAAVVTDVGAPLSHAAIVARELGIPAVVGCGNATMRIRTGDRLRVHGERGEVHLIDPPTEGGAPPTGA
>CP025990.1|AUS80832.1|5586775_5587531_+|TetR/AcrR-family-transcriptional-regulator
MVIRFGGVRVASDERDDAAASGDTRRDRAGRILDAASALTLRWGYQKTTIDDIARAAGVAKGTIYLHWKSRDALFLALLRRERALAATEIRDLAAQDPAGHTLRGVLVHSYRVVARRPLLLAVLTRDRDVLGRLLTTGAPTARPPLSVGFPRYLEHLRAGGWVRTDQTLAAQLSLGTATIYGFLLTRPLMPDEFAVTDDDAAELVADTVCRALDRGSPLGDTETEGVAAASAAYLAEAARFTIERYENEVA
>CP025990.1|AUS80841.1|5601216_5601645_-|pyridoxamine-5'-phosphate-oxidase
MSTTPSSLTPEDLEFLSRPLHGFLTVAAGPLPPQPRPVWFEATAEGTIQLFTGPDSPKVRRIRRDPRASLVVGSPVGESERWVSVAGRVEVVPDGALELCSRLAARYWDLNDPGRAEELAGMMSDEQVRLVIHPETVRRFPL
>CP025990.1|AUS81986.1|5601799_5602636_-|NAD(P)-dependent-oxidoreductase
MRNDTTLVLGATGKTGRRILARLRLRGIPVRAASRSTQPRFDWSDPDDWGAVLEGVDAAYVVAPTVPGPVHEFVAQAEAAGVRRLVLLSGRGADDWGDSTFGLDMLSAEEAVRGSALEWTVLRPSNFAQNFSEDLFHAPLVAGELALPAGAVPDPIIDVEDVADAAVTVLTEPGRHAGGVHELTGPRALTYPEAVDLIARASGRPITYRRISPTEYAATLVEQGLSQDDADHVAEMFVMMERGALASPTEDLAALLGRAPRTFEDYVVRAAAAGAWRP
>CP025990.1|AUS80842.1|5602716_5603715_+|AraC-family-transcriptional-regulator
MDAFSDLLRGVRAHGSLVGSSTHTPPWALHFVDGAPLTLCTVLTGGGWIVPEDGAPEPLRARETIIVRGPGTFSFVDEVGTSAEPIPCGELCATPEEGGTRHRRGWHDPGSPEPGRESTTLIVGAYPVRGEISRRLLEALPGVLRVCAGGTGDPVLDHLAAEVAVDAPGQQVVLDRLLDWMLVCTLREWFDRPGGEPPAWWAAQHDAVVGGALRLLHGEPAAPWTVAALAARIGVSRSTLAKRFADLVGEPPLTYLTRWRMTLAADLLAERGSDTLEEIAHAVGYSDAFGFSAAFKRVRGVSPSEFRRAATTLDPAPVGFVPAGTIPVGGHV
>CP025990.1|AUS80843.1|5603721_5603964_-|hypothetical-protein
MFRAGHHAGRTRPGTGAATARGALAEVHAQTAGRTTEALRAYLLDPRHAQRLAAGLAAAWRARFGGRGMAAPPPVWPRTG
>CP025990.1|AUS80844.1|5603997_5604348_+|hypothetical-protein
MIRSSRRTRLTRTNQAAVSRNRSAAACSGAVTNAAPSSVTTGPAHSGWSAGRITSGSSTSFTVRLSGPPRGPLNASTPWRPRHTSSSTAALGRRPSISWRLSLLVGVPSPVGMAPG
>CP025990.1|AUS81987.1|5604444_5605242_+|hypothetical-protein
MRTALRSLALLALLGSAGYYLWFGLTNQGDDDLPGMSWVGPQMVPLMIALPATIMIFSFTGHGVMTALTGRNSAAFRRGQLGVGTVVGTSPTGATVNDQPELRIDLTVRTADGLQFASHARMVVPVTEVAALRPGAVVPVRYVPGRIDRVELDLSGDAARAQDVMNQIALQQGTLDPGRLEVAKRGTPAQGLVRALEVPGEIRDGQARLDITLLVTRPDGTTFETRVEKFVPPHMVAHVQVGRIVAVRYLPEDESRLVLSLPVNG
>CP025990.1|AUS80845.1|5605534_5607175_+|D-xylose-ABC-transporter-ATP-binding-protein
MGGTTHSSTDPFPPLLDVSDVTRSFPGVRALSGMRLDLRHGEVLALVGENGAGKSTLMRLLSGVDQPDTGRFLLDGREIRPSGPGHARSLGIGIIHQEFSLVPDLTVAQNLFLGREPRRWRWFVDRRALDRRAAELVAELGLPLDPDAPVATLSVAHQQLVEIARALSHRPRVLIMDEPTAALDADEVETLHALIRRFQGPNTGVIYISHRMDEIRRVADRITVIRDGRYVATRAVSTTSTDEVVSLMVGRAVATSTAPAPTRVARRPGPVVLSVRGLSTRGLLRDVSFDLHEGEILGFAGLMGAGRTETARALVGADPSTGGTVEVRGRPARIRNPAEAAALGVGYLSEDRKRYGLLLDHDVGTNITLAALASRFATAGVVRRRAARTAAQGYVRALGVRTPSLDRPVRNLSGGNQQKVVLARWLARDCDVLIVDEPTRGVDVGAKEEIHQLLEGLANDGTSVIVISSELPEVLRLSDRVVVMSEGRVTGILPAAEASQEAIMRYATLRPENTGTPPPDRDAPGDQYRAGAPDPTAPEHGREARP
>CP025990.1|AUS80846.1|5607171_5608182_+|ribose-ABC-transporter-permease
MTATDTTDTVDHPARRGGLAGAARARLQQLLALASLLVIGAFFSVASPFFLTYGNFTAILFSTVVIGTLAVGTTLVIVSGGIDLSLGTGMALCAVVAGVLMVDLGLPLAVGVPAAILFGGLIGLVNGLNVTLLGIPPFIATLAMMLVAGGLALVLSNSAPIYFTDVPGYLDISTGNLVPGVDFPNAVLILLVAAVVAGLVLSRTVLGRHTYSVGSNEAATALSGVDVRRVKIAVYVLAGLFTGLAGILISARLGSAQPATGMGYELQAIAAVVIGGTSLSGGRGSVVGTLIGALIISVLNNGLQIMSIPQEWQNVILGCVILVAVYADMLRRRRQG
>CP025990.1|AUS80847.1|5608227_5609181_+|BMP-family-ABC-transporter-substrate-binding-protein
MRGIRPLAVLGALAVALTGCGPGWGHDPDLPHIAIVSKGFQHQFWQAVKRGAEEEAERRGAGVTFMGPPTEQDVEAQLNMLTNAIARQPDAIGLAALDSRATEPLLRQAEEAGIPVIAFDSGVDSEIPRTTVATDNRAAAALAAEHLAGLLGGTGTVGLVVHDQTSGSGVDRRDGFLDWMRANAPGITVLDPQYGGGDQLVSADITKAVLAANPDLDGLYASNEGSAVGVLRGVAESGHEDLVVVGFDSGRAQLDAVRDGTLAGAVTQDPIDMGRRLVLAGLAAMDGEELPATVDTGFHWYDARTVDDPALAGVLYQ
>CP025990.1|AUS80848.1|5609646_5611284_-|hypothetical-protein
MFWQEGSGEVSGFLLFRVGLRDEGLRHAGLTSVVVSMVQRVTGFFVPTSWSGSTLDTVVFAATGARAEVCAQLDEVCELLADPPEDLIENVLSDRGAAGWLDVPRPTAALLRHDYGSTGIGAAYWADDIPLDRFTPREVREHLARYFVAGNAVCAITTPVLDGAMRLPLPPGAAPRRPAITPNQRSSAEWFSGGPPPYSGVGVMLPGTLDAVWAVTQDVLDLRLHPVQESLVDRWDGQDRILGQTMLSSDTVHVAIDLFCEHDASARAAGAVWAALTELAAAGPDQDELTALLERRRRSDAGHRDTERAASRVFRRAHLALFGVTGSDGCDERSRARVRPEQVAAALRTAMRSALVVVPDGVELALPGVEHVIPTSLPPEGGARFEATGGCPPGQDRELLVEGADRLCHRNALGRWQSVAWSEVVGWSVWRGVAVVYGRNGEKIVADPHRFPGCEPLVSRLPDLVPSELGWPGSMEEVDIVAAGLARQAMEDLHSAPEGGLDHFVYQEMSVRELERRLPSASGVLRRQVARNLRSLGVDGPLHRS

Crispr_ID: CP025990_43

• CRISPR_ID: CP025990_43
• CRISPR_location: 6195963-6196663
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 11 spacers

Consensus repeat of CP025990_43

Consensus_repeat	Method
CGGAACAGCCCCGCGTGCGCGGGGACGACAC	PILER-CR
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CRT
GGAACAGCCCCGCGTGCGCGGGGACGAC	PILER-CR

spacers of CP025990_43

>43.1|6196005|19|CP025990|PILER-CR
ACCCGCCGATCTGGCGATC
>43.2|6196066|30|CP025990|PILER-CR
GACTCCTCGTGTACCACGGCCCGCAGTACT
>43.3|6195993|33|CP025990|CRISPRCasFinder,CRT
CGCGTCGCCGAGACCCGCCGATCTGGCGATCTT
>43.4|6196054|33|CP025990|CRISPRCasFinder,CRT
GGACTCCTCGTGTACCACGGCCCGCAGTACTGG
>43.5|6196115|33|CP025990|CRISPRCasFinder,CRT
GCTGCGCCCGCGCCGCACGCCGGTCCGCCGGAG
>43.6|6196176|33|CP025990|CRISPRCasFinder,CRT
CCGGACGAACGCCACGCTCCGGCACCTCGACCA
>43.7|6196237|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
GCTGGCGCAGATGCTGGACGTGCCACCGCGCGC
>43.8|6196298|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
GTACCGGGAAGGTCCTCGGCGGAAGCCGGGGCG
>43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
CCCTGGCCCCGGTCCGCCGCCGCCTGATCGCCC
>43.10|6196420|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
CGCATCCAGCAGGCCCGTGACCTCACCCGACCC
>43.11|6196481|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
CCGGTACGAGTCACGCTGCCAGGCGTGCGGGCA
>43.12|6196542|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
CCCGTGGTGGGTACTCAGCGACATTGCGAAGAT
>43.13|6196603|33|CP025990|CRISPRCasFinder,CRT
CGCCCTCATCGTCGGAAAGCGGTACGAGAACCC

CRISPR arrays and Neighbor proteins around CP025990_43

CRISPR arrays

The CRISPR arrays of CP025990_43

>merge|CP025990|43|6195963-6196663|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCGTCGCCGAGACCCGCCGATCTGGCGATCTTGTCGTCCCCGCGCACGCGGGGCTGTTCCGGACTCCTCGTGTACCACGGCCCGCAGTACTGGGTCGTCCCCGCGCACGCGGGGCTGTTCCGCTGCGCCCGCGCCGCACGCCGGTCCGCCGGAGGTCGTCCCCGCGCACGCGGGGCTGTTCCCCGGACGAACGCCACGCTCCGGCACCTCGACCAGTCGTCCCCGCGCACGCGGGGCTGTTCCGCTGGCGCAGATGCTGGACGTGCCACCGCGCGCGTCGTCCCCGCGCACGCGGGGCTGTTCCGTACCGGGAAGGTCCTCGGCGGAAGCCGGGGCGGTCGTCCCCGCGCACGCGGGGCTGTTCCCCCTGGCCCCGGTCCGCCGCCGCCTGATCGCCCGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCATCCAGCAGGCCCGTGACCTCACCCGACCCGTCGTCCCCGCGCACGCGGGGCTGTTCCCCGGTACGAGTCACGCTGCCAGGCGTGCGGGCAGTCGTCCCCGCGCACGCGGGGCTGTTCCCCCGTGGTGGGTACTCAGCGACATTGCGAAGATGTCGTCCCCGCGCACGAGGGGCTGTTCCCGCCCTCATCGTCGGAAAGCGGTACGAGAACCCGTCGTCCTCGCGCACGCGGGGCTGCTCC

>CP025990|43|36|6195963-6196115|PILER-CR
GTGTCGTCCCCGCGCACGCGGGGCTGTTCCCGCGTCGCCGAG	ACCCGCCGATCTGGCGATC
TTGTCGTCCCCGCGCACGCGGGGCTGTTCCGGACTCCTCGTG	TACCACGGCCCGCAGTACTGGGTCGTCCCC
GCGCACGCGGGGCTGTTCCGCTGCGCCCGCGCCGCACGCCGGTCCGCCGGAGGTCGTCCCCGCGCACGCGGGGCTGTTCCCCGGACGAACGCCACGCTCCGGCACCTCGACCAGTCGTCCCCGCGCACGCGGGGCTGTTCC	GCTGGCGCAGATGCTGGACGTGCCACCGCGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTACCGGGAAGGTCCTCGGCGGAAGCCGGGGCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCTGGCCCCGGTCCGCCGCCGCCTGATCGCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCATCCAGCAGGCCCGTGACCTCACCCGACCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGGTACGAGTCACGCTGCCAGGCGTGCGGGCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCGTGGTGGGTACTCAGCGACATTGCGAAGAT


>CP025990|43|41|6195965-6196663|CRISPRCasFinder
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCGTCGCCGAGACCCGCCGATCTGGCGATCTT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGACTCCTCGTGTACCACGGCCCGCAGTACTGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCTGCGCCCGCGCCGCACGCCGGTCCGCCGGAG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGGACGAACGCCACGCTCCGGCACCTCGACCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCTGGCGCAGATGCTGGACGTGCCACCGCGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTACCGGGAAGGTCCTCGGCGGAAGCCGGGGCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCTGGCCCCGGTCCGCCGCCGCCTGATCGCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCATCCAGCAGGCCCGTGACCTCACCCGACCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGGTACGAGTCACGCTGCCAGGCGTGCGGGCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCGTGGTGGGTACTCAGCGACATTGCGAAGAT
GTCGTCCCCGCGCACGAGGGGCTGTTCC	CGCCCTCATCGTCGGAAAGCGGTACGAGAACCC
GTCGTCCTCGCGCACGCGGGGCTGCTCC

>CP025990|43|34|6195965-6196663|CRT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCGTCGCCGAGACCCGCCGATCTGGCGATCTT
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GGACTCCTCGTGTACCACGGCCCGCAGTACTGG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCTGCGCCCGCGCCGCACGCCGGTCCGCCGGAG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGGACGAACGCCACGCTCCGGCACCTCGACCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GCTGGCGCAGATGCTGGACGTGCCACCGCGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTACCGGGAAGGTCCTCGGCGGAAGCCGGGGCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCTGGCCCCGGTCCGCCGCCGCCTGATCGCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCATCCAGCAGGCCCGTGACCTCACCCGACCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGGTACGAGTCACGCTGCCAGGCGTGCGGGCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCGTGGTGGGTACTCAGCGACATTGCGAAGAT
GTCGTCCCCGCGCACGAGGGGCTGTTCC	CGCCCTCATCGTCGGAAAGCGGTACGAGAACCC
GTCGTCCTCGCGCACGCGGGGCTGCTCC

>CP025990|43|37|6196209-6196602|PILER-CR
	ACCCGCCGATCTGGCGATC
TTGTCGTCCCCGCGCACGCGGGGCTGTTCCGGACTCCTCGTG	TACCACGGCCCGCAGTACTGGGTCGTCCCC
GCGCACGCGGGGCTGTTCCGCTGCGCCCGCGCCGCACGCCGGTCCGCCGGAGGTCGTCCCCGCGCACGCGGGGCTGTTCCCCGGACGAACGCCACGCTCCGGCACCTCGACCAGTCGTCCCCGCGCACGCGGGGCTGTTCC	GCTGGCGCAGATGCTGGACGTGCCACCGCGCGC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	GTACCGGGAAGGTCCTCGGCGGAAGCCGGGGCG
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCTGGCCCCGGTCCGCCGCCGCCTGATCGCCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CGCATCCAGCAGGCCCGTGACCTCACCCGACCC
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCGGTACGAGTCACGCTGCCAGGCGTGCGGGCA
GTCGTCCCCGCGCACGCGGGGCTGTTCC	CCCGTGGTGGGTACTCAGCGACATTGCGAAGAT
GTCGTCCCCGCGCACGAGGGGCTGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81160.1|6214568_6215702_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
CP025990.1|AUS81146.1|6185498_6186740_+|cytochrome-P450	unknown	unknown	gnl|CDD|275308
CP025990.1|AUS81148.1|6188594_6191489_+|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS81147.1|6186777_6188031_+|glycosyl-transferase-family-28	unknown	unknown	gnl|CDD|275309
CP025990.1|AUS81154.1|6204608_6205199_-|type-I-restriction-endonuclease-subunit-M	unknown	unknown	gnl|CDD|368218
CP025990.1|AUS81159.1|6212992_6213889_-|hypothetical-protein	unknown	unknown	gnl|CDD|380454
CP025990.1|AUS81149.1|6192155_6192923_-|thioesterase	unknown	unknown	gnl|CDD|225749
CP025990.1|AUS81158.1|6212207_6212996_-|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
CP025990.1|AUS81156.1|6206192_6210737_-|hypothetical-protein	unknown	unknown	gnl|CDD|237108
CP025990.1|AUS81155.1|6205557_6205743_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81157.1|6210775_6212005_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
CP025990.1|AUS81161.1|6216169_6217492_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81152.1|6196776_6197679_-|hydroxyurea-phosphotransferase	unknown	unknown	gnl|CDD|309685
CP025990.1|AUS81142.1|6178548_6179922_-|hypothetical-protein	unknown	unknown	gnl|CDD|341142
CP025990.1|AUS81143.1|6180893_6181091_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
CP025990.1|AUS81151.1|6195501_6195954_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS81153.1|6201203_6201938_-|hypothetical-protein	unknown	unknown	gnl|CDD|223861
CP025990.1|AUS81145.1|6183778_6184507_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187585
CP025990.1|AUS81144.1|6182708_6183695_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182137
CP025990.1|AUS81150.1|6194533_6195127_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81160.1|6214568_6215702_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.43331e-65
CP025990.1|AUS81146.1|6185498_6186740_+|cytochrome-P450	gnl|CDD|275308	TIGR04515, cytochrome_P450_monooxygenase, P450-derived glycosyltranferase activator. Members of this family resemble cytochrome P450 by homolog, but lack a critical heme-binding Cys residue. Members in general are encoded next to a glycosyltransferase gene in a natural products biosynthesis cluster, physically interact with it, and help the glycosyltransferase achieve high specificity while retaining high activity. Many members of this family assist in the attachment of a sugar moiety to a natural product such as a polyketide.	2.74195e-94
CP025990.1|AUS81148.1|6188594_6191489_+|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	7.42055e-12
CP025990.1|AUS81147.1|6186777_6188031_+|glycosyl-transferase-family-28	gnl|CDD|275309	TIGR04516, probable_glycosyltransferase, glycosyltransferase, activator-dependent family. Many biosynthesis clusters for secondary metabolites feature a glycosyltransferase gene next to a P450 homolog, often with the P450 lacking a critical heme-binding Cys. These P540-derived sequences seem to be allosteric activators of glycosyltransferases such as the member of this family. This model describes a set of related glycosyltransferases, many of which can be recognized as activator-dependent from genomic context.	0
CP025990.1|AUS81154.1|6204608_6205199_-|type-I-restriction-endonuclease-subunit-M	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	4.04993e-40
CP025990.1|AUS81159.1|6212992_6213889_-|hypothetical-protein	gnl|CDD|380454	cd19531, LCL_NRPS-like, LCL-type Condensation (C) domain of non-ribosomal peptide synthetases(NRPSs) and similar domains including the C-domain of SgcC5, a free-standing NRPS with both ester- and amide- bond forming activity. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. Streptomyces globisporus SgcC5 is a free-standing NRPS condensation enzyme (rather than a modular NRPS), which catalyzes the condensation between the SgcC2-tethered (S)-3-chloro-5-hydroxy-beta-tyrosine and (R)-1phenyl-1,2-ethanediol, forming an ester bond, during the synthesis of the chromoprotein enediyne antitumor antibiotic C-1027. It has some acceptor substrate promiscuity as it has been shown to also catalyze the formation of an amide bond between SgcC2-tethered (S)-3-chloro-5-hydroxy-beta-tyrosine and a mimic of the enediyne core acceptor substrate having an amine at its C-2 position. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	8.08741e-35
CP025990.1|AUS81149.1|6192155_6192923_-|thioesterase	gnl|CDD|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	5.78442e-86
CP025990.1|AUS81158.1|6212207_6212996_-|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	5.56665e-28
CP025990.1|AUS81156.1|6206192_6210737_-|hypothetical-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
CP025990.1|AUS81157.1|6210775_6212005_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.84888e-59
CP025990.1|AUS81152.1|6196776_6197679_-|hydroxyurea-phosphotransferase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	1.37971e-65
CP025990.1|AUS81142.1|6178548_6179922_-|hypothetical-protein	gnl|CDD|341142	cd17253, RMtype1_S_Eco933I-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Escherichia coli O157:H7 EDL933 S subunit (S.Eco933I), Escherichia coli O104:H4 2009EL-2071 S subunit (S.Eco2071ORF3585P) TRD2-CR2, and Streptomyces species SirexAA-E S subunit (S.SspAAEORF2129P) TRD1-CR1 and TRD2-CR2. Escherichia coli O157:H7 EDL933 S subunit (S.Eco933I) recognizes 5'... CACNNNNNNNCTGG ... 3' and Escherichia coli O104:H4 2009EL-2071 S subunit (S.Eco2071ORF3585P) recognizes 5'... RTCANNNNNNNNGTGG ... 3'. The recognition sequence of Streptomyces species SirexAA-E S subunit (S.SspAAEORF2129P) is undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.Eco2071ORF3585P TRD1 recognizes RTCA/TGAY and S.Eco2071ORF3585P TRD2 recognizes CCAC/GTGG. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	1.50449e-73
CP025990.1|AUS81143.1|6180893_6181091_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.51383e-18
CP025990.1|AUS81151.1|6195501_6195954_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	1.3626e-08
CP025990.1|AUS81153.1|6201203_6201938_-|hypothetical-protein	gnl|CDD|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	1.5811e-07
CP025990.1|AUS81145.1|6183778_6184507_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.81695e-85
CP025990.1|AUS81144.1|6182708_6183695_-|LysR-family-transcriptional-regulator	gnl|CDD|182137	PRK09906, PRK09906, DNA-binding transcriptional regulator HcaR; Provisional.	1.13104e-31
CP025990.1|AUS81150.1|6194533_6195127_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	6.28261e-13

Protein sequences

>CP025990.1|AUS81151.1|6195501_6195954_-|DUF3558-domain-containing-protein
MRRYERHDRFSFTEDIANVLPCEVLDDNQITDLGFDPTTADFTDVGLLYTCQYTVAPMETPLMSIGLDADRALDELNLTNFNSTEHQVGPLRALLITDDRDPTMCQISMELAETAHVTVRVSWAESQEAACEAAERVAAVVEPELPREQS
>CP025990.1|AUS81150.1|6194533_6195127_-|DUF3558-domain-containing-protein
MTRRTPPHRHTPALAGITLLTVLTGCTTETTGQAHTPTTANTTNSTTAEGTTAPGNSTFTEELANVLPCQVLDDNQVTDLGFDPTTAEFDDVGVAYMCLYRPAPLESPLLSINIDKDWALDELNLTNFNSTEHQVGPLRALLITDDRDPSMCQISMELAETAHVTVRVSWAESQEAACEAAERVAAVVEPELPREQS
>CP025990.1|AUS81149.1|6192155_6192923_-|thioesterase
MLDTNSTTDLWIRRYHPAPGSPPRLVCLPHAGGSASYYFPVSQALAPDVEVLAVQYPGRQDRRAEPFLRTIEQLADAVTAELIKVVGDEPERPLALFGHSMGAAIGFEVAVRLERAGLVAAGLFVSGRRAPSVHRDERVHLRDDAGLLEDVAALGGTNMRAMDAELRSMALPAIRNDYTAIETYRYQPGPRVNCAIHAMVGDSDPKAAVEDVRAWADHTHDEFVLDVFPGGHFYLDQHAPTILGKITDRLGRART
>CP025990.1|AUS81148.1|6188594_6191489_+|hypothetical-protein
MSVPSRRNAFSRARNSAHHRSPHVFAGRTRTVGAAGCPPVSSRTDTTGFEAKVGCFWIGGRTVELLERHAESAALRRAYHDGGGAVVLVSSCVGGGKTGLLQSFGEYVASAGGVVVSVVGSRAERTFGFGVLEQVVASPSLSSQVRCRLRDLLDRAIGGGAAPQGGESAAVEVFVDALGGALADLASEQGITLCVDDVHFVDEVSLRCLLSVQRRMVAAGGVVVFGETPQLAVTHSQVHAELMDQPRYQWIRLSRLSRPGVAAAVTRRLGDTPPPVVEACCEATGGNPRLVRAALDDHAAAEEHSELVVGLTFRHAVLACLCRLDSRVLEVARGIAVLGEQATPDRLVKLLGLKAGVVRRSVELIAAIGLVRTDRFRHPAVREAVLGTLPPEDHTRLASRAAWVLHQDGADATSVVRHLLAAEQAEQTWMIGVLQDSARQALADGNAGTAVRCLDLASRGIVGDRERAENTARLAAAEWRMNPSAAASHLGTLTQAMRDGLLDQREIVALIKYRLWFGEVDQAADVVARLVAGGTLLDWPLVAELRIAHQVSHFGKSPMWDLLDKVGPGPVDNEVVTGSAQMAVRLMTLLLTNGSQKQVVTAAEQILLNSQVDESSFESVVCALQALIQVDRPGKALDWSTRLLDLPIIRGASTWRAVLSAISTHAAVRCGKPPRATALATSMFATLPVHSWGLTVGLPLSDLLHVATAQGATAEAEQVLRQVVPERMLSTWSGLRYLRARGHYYLAHNRVYAALEDFRRCGDMMTAEGVDIPAVIPWRADIAQAYLRLDLREKAKKLVEQQLALPGASSARVRGASLRVLALTSEPPQRRKLLEKAVNLLRESGDQVELSMALSDLHTTGHRPNQPSVPALLGRGTSKAPVIDLPRHDRVSTLPRGEQLLSSAERRVADLVALGDQNRNISTKLHITISTVEQHLTKIYRKLGVANRNELRARLEIGNGVRSD
>CP025990.1|AUS81147.1|6186777_6188031_+|glycosyl-transferase-family-28
MRVLFTTYAEKMHLYNLVPIAWALRTAGHEVRVASQPELTGAITEAGLTAVPVGTDNKVQQSIGRWGEAAMSHPEIDLAENRPERLTWDYVSGIYTVTVPFLYSVVNNDSMVDDLVAFSRQWRPDLVVWDMLSYPGSVAARACGAAHARMIAGLDILARMRFTFLDRMREQPPEWRDDPLAEWLTWTLARFGCDFDEEVVNGQWTIDPTPDRMRLPLDLNYLPVRHVAYNGPSVVADWIREPPRRPRVCLTLGVSEQSRTGGQTRSVTDLLAAVADLDVEVVATLDPADHPGRVGVPDNVRLAGYVPLHALLPSCSAIVHHGGSGTMSTALGLGVPQLVVPKYWESVERASRLEELGLAISVPAAELTPQALRDGLSRLLTEPAFREGAGRISDEIGAMPSPNEIVPVLEKLTSEHR
>CP025990.1|AUS81146.1|6185498_6186740_+|cytochrome-P450
MTRLTDEELGHELQMRRGVVWLTGTLDDPYALLLKGRHEDLAGLHAEVRRRGPLYRSPLGAWVTASHEVGASVVGDRRFGVRKPDGQRIIPRLVEVDDSFAGLDGDRHRQLRALSTPFLMAGTEDAYRDGLASDCRGLLDRIERPGGFDLLADVAGPVATAAMARLLGIPTSHRTSFDEHCARIGFSVDVPSLRVARELGTAATGLERLFRDLVDRRSADPADDVVSGVIAAAEAVGVATEDVLGLLVMLTAIGVEATRNLIGNAVLALLEDPARWAAFRDEQDLVSKVVDETLRYAPPITLLNRIAHVDVEVAGTRLRAGSRVVVLVGAANRDPEVYPRPDVFDLDRPPGPTPLSFGGGPHHCLGRHFARTVTEVALRALASGAPALRTEGEVLRSRWMPSTHRILRFPVSA
>CP025990.1|AUS81145.1|6183778_6184507_+|SDR-family-NAD(P)-dependent-oxidoreductase
MDQVNDTKTALVTGANKGIGFAIAQGLGMIGFTIAVGARDDTRREDAVDRLGATGITAFGVSLDVTSDESAGAAAEAVERRAGRLDVLVNNAGIAGRADNGRQDPTTLDLDVLRTVLDTNVLGVVRVTNAMLPLLSRADAPRIVNVSSTMGSLALGAGGPLMAAYAPSKSLLNSMTAQYARRLADTPVIVNACCPGFVATDFTGFDAPRTPEQGAAIAIRLATLPDDGPRGGFFDDGGTVPW
>CP025990.1|AUS81144.1|6182708_6183695_-|LysR-family-transcriptional-regulator
MHDLETRQLRYFVAAAEELHFGRAARRLGIAQPPLSRAISQLERRLGVSLLDRNRRGVALTAAGEVMLREARVALDAVAAVARRTRRAGDPARPLVLTTKAGASHELLRRLLDTLDDEPGAVPIEVLPCEVGEQARLLRDGRADVAVMHRPFDDLAGFDTEDLCVEGQVALLPAGHPLAALEQLTLADVQDVPDLPIARWPRIDGSYPDGPGPEVRSQSQLAQLVALGRTLLVIPASSRAWQWPAHVAVPVIDAPRVTTVIAWPPSGYSPAVASLVATAARLRDTPPPPPSRTAPACPGMIVSTAHQAGGQRTPADGREAKPLERDGR
>CP025990.1|AUS81143.1|6180893_6181091_+|DUF397-domain-containing-protein
MNADMTLTNWRKSSRSSNGSDNCVEVGSTSTVVAVRDTKNRAGGKLVVDHEVFAAFVGSLKRDGV
>CP025990.1|AUS81142.1|6178548_6179922_-|hypothetical-protein
MSAHVTWSVAPLWSLGVERRHVVDPGDLGGRVVHYSIPSVDAYGTGREEGPDSIRSAKLRLRGGEVLISKLNPRKSRVLIVQKSNDPIVSSTEFVGIEPVEVLESRFLFYFLQAESTRQALDSQVQSVTRSHQRVSPEDVMHLSVAYPSLEEQRRIVDFLDAETARIDQVVSMRQGQLELFEERKQAAMDHFLVQEGDPMVRLGRLCRVQSGVTVDGGRISKDAVTRPYLRVANVQAGCLELSEVKEIMIDRTSVRRFELRPGDVLMTEGGDLDKLGRGTVWSGEIRGCLHQNHVFAVRPGSKLLGKYLALLTRTSLARSYFEMTGSKTTNLASTSSGKILSFRVPLLGMEEQRYRAKNAEKDLSWMAALTASMKQQINLLSERRQALITAAVTGQFDVSAASGRGIEERRPGCWRRCRSVRASGRPSRGSAREVPRPWAGRTLPRSPIRAYPFSRK
>CP025990.1|AUS81152.1|6196776_6197679_-|hydroxyurea-phosphotransferase
MPARDGRRHRYRRRRRRHGPHDGRRRRREPDLELDRWELRRDGDATSGAASLVLPVLRANGTPAALRLQMPREETTAALVGLRTWNGSGIVRLLDHDADSSAMLLERLDGARTLSSIEDDDVAMSILAEIQARLVSSAAPPELRGLRDIATDMLARVPSAITALTDPSDQQHLRGWASAVAELIDEPGDRLLHWDLHYDNVLAADREPWLAIDPEPLAGDPGFDLWPALDSRWDDVVAGGDPQRVLRRRFDLLTEVLRLDRARAAGWTLGRLLQNALWDIADGETRLASSAITMSRALGR
>CP025990.1|AUS81153.1|6201203_6201938_-|hypothetical-protein
MMVNLGMLLAEVGRVAEAEVWLRRAVDAGVDHAMLGLGCVSAEVGRVDDAEFWYRRAVEAGDSAANRLLDDLYVNSGRFYDAEVWYRRAAEDGVDEAFVNVGFLLVSAGRVGEAEAWFRRAVDAGINEALLGLGLLSAKAGRVGEAEIWYQRVIESEASGVMFDLVIMYARTGHAGEAEVWIRRAVDSSIKEKMAGPLFLMVNDGHGKGTELAVRSLFQAYRLIGVEYLLDGALDLLRSKNEEA
>CP025990.1|AUS81154.1|6204608_6205199_-|type-I-restriction-endonuclease-subunit-M
MIDEFAKEYLHGDLREARETVVWKLDGLSEYDVRRPLTPTGTNLLGLVKHLTRTEARYFGDAFGRPFPEPVPGHGDDAELDADKWVTADESRDEIIDRYLRVSAHSDETINELRVDAPGHVAHWPRPDVKLFNVLVHVLTETTRHAGHMDILRETLDNAVGTDLATAKYLDRGAGYWEAHYARVEEAAKPFSATSP
>CP025990.1|AUS81155.1|6205557_6205743_-|hypothetical-protein
MDVPDRDREQLASWNTLALAQHLAQWRALKGGVAGIDTATDEILRWTTPSMQFGATLLPTP
>CP025990.1|AUS81156.1|6206192_6210737_-|hypothetical-protein
MAHLSYAQRRMWFFDQTNGPSSTYNVARVFHISGPLDRDALAAGLADVVERHDVLRTIYPPIGDDVTQLVVDPAAPENLLHRRSIAEPELAEAMNVEASRPFDLTNDIPIRATLFELENGEHRLLLVFHHIAIDDWSYRLLLCDLTTAYTSRLAGKRPPFDPLEMRYTDYVLWQQEFLDAGGGDDEVPATPLEFWRRHLAGLPEELELPYDRPRPDVSAHVGGIVEVSIDSATHGRLAALAAATNSTTFVVCQAALGAWLSCAGAGIDIPVGMAYASRDDASLEEVVGMFINTLVLRLDLAGDPTFAELVRRTRGTVLDALDHSTVPFDQVVEAVNPTRSSNRNPLFQVMTNWQEDMGDDGGLRLDGTRVEALQTRNSKAKFDLSVYFAERKNGDVPAGIDIVLGYDVGLFDQETAQSMVGWLATVLDEISTDPGRRLSEIEFVGPAERELVLRTWNDTAAGPATQHLPGMFTDQVRRSPDAVAVESPDEVITYAELNARANRLAHLLLRHGAGPETCVAVVVPRTTALLAMLAVLKAGATFLPIDPDYPADRIAYILDDAEPALVLTTATLDLGLGDRRVLVLDGPEVTAALADCPETDPGASDRPAPLEPDSPAYVVYTSGSTGRPKGVVVTARVLINLLRWQLGTMGAEPGTRVSQFSAISFDAFEQEILAALFTGQTVVVPSEDTRRDPNALARWLEQRDINEFLAPDIVVRATLEAATEQNLRLDRLRTVIQGGEPFQLTGHLREFHRQRPAITVFNHYGPSETHVITGVTLPGDPDVWPTVAPIGKPIWNCQTYVLDAKLRPLPVGVAGELYLAGAGLARGYLRRPGLTAERFVANPFGAPGERMYRTGDVVRWNRQGELLIVGRTDDQVKIHGIRVELSEINSVLRGHPLVAQAATLLRQHSSGDKQLVSYVVPATSVELEPADLRRHAAKLLPAAVVPSAFVVLEALPLNSNGKLDRQALPAPDFSALSRASGRPPRSPMEKALCQIFGGVLKTPSVGADDNFFDLGGHSMLVIRLLKRVQAELGVELNVRTVFEHPTVAALAAAAETMDGPAQVTLAPTPRPEHVPLSFAQRRLWFVDQLEGPSSQYNLAPIKWRITGDLDLDALAAALTDVVVRHESLRTVFPDINGRPFQRILPAGEVTVRLERQQGEPGDLAEWTASVCRHEFDLANELLVRADVLSLAPDDHAFVVVAHHIVADGWSVAPLRRDLATAYAARTRGRAPEFSPLPVQYAEFTLWQHEALGQENDPTSVLAEQAGVWRRTLADVPDVVSLPNGRSRPETVSARGASADFLVEPALYDRVRSLARTAHATPFMVLHAALAALLTQLGAGSDIVMGAAVAGRSDAQLDDLIGCFVNTVVLRIDTSGDPTFQELLARTQEADLMAFQNQDLPFEHVVRMLKPARSRSHHPLFQIMISMQTGGQGAGLPGLHVDDLAISTTSTSKFDLSIGFMESASGSLQGKIQYATDLFDRSVIDELTDGLVALLQRVVSRPDLSLGAAHLTAYR
>CP025990.1|AUS81157.1|6210775_6212005_-|MFS-transporter
MLLWVGQSIGDIGSAVTQLALPMVAVLVLNASTLEVGLLSAMTTLPNLLVSLHAGSLVDRLPKRKMMLFCHIGRFVLLASIPITTIPGLGLRLTYSHLLVVALLTGVLTVFFMIAYQSYLPILLSSDELLDGNGKVGATQSFAYSAGPAIAGALVGLVGVVRAIAINVASFGVSAVSLFLIRKEEPPIEPRPAGHKMRHDIFEGLRFVVKHPVLRKVVACTGTSNFFSAMGFAVEMVFLLRILNVAPALVGLIFSVSAVGGVVGGILAGRLSKRVGNARIIWFSILVLGFPSLLMPLAQPGFGVLLYAVGLFFFMTMAVMYNVAQVTYRQVITPPALLGRMNASVRFIVVGTSPLGAALGGVLGTAIGVRPTLWIAFAGAWLAGLWVFFSPLRKMRDFDDNRDDAEQSA
>CP025990.1|AUS81158.1|6212207_6212996_-|FkbM-family-methyltransferase
MTSLRMLPNGLNVVQVNQTETDYLYREIFTDAVYLPPGGITLPDRPVVVDVGANIGLFTLFAASQWPGAVVHACEPVPDVFDVLRDNIRALPGATAHNVALGGSAGRRELTYYPSYTMMSGFDADDEANRELVRAHITNTSGPERRAAVLDAVDAVLADRLVGQNVACEVTTLTQFVADFAVERIDFLKVDVEGAEVEVLQGIDGDTWRKIGFLAVEVLDRDGELAEVRRLLRENGFSSAEHQEAAYWGTGLHLVYARLAGL
>CP025990.1|AUS81159.1|6212992_6213889_-|hypothetical-protein
MALTRVGCLSSSPSTPTTRLPRARHAGAPSPSSTTAPRRCGPTRTSFAVDHWLREIGPPVEPLHWPFEERRLPAFPHQGDTWEIRLPADVDALVHEFANTARATPFAVLMAAYAVLIGEVCRTDTPVIGGGLRNRRLPGIDRTVGMFVNQCAFSYEDWRSRTFAELAQSTTSRLAAAMDHQEVPFPLVTQHLTLSRDRSRNPVFQTCISMNDWPDTQLDYGPGMTVDVSFPSNGGAKFDLDIIVLPEPGGTRMLWRYSTPLFTAADAEDLVSRYLALVTDLVAAPHALLGARTEQVAS
>CP025990.1|AUS81160.1|6214568_6215702_-|serine/threonine-protein-kinase
MNATPARIGRYVVERELGSGGMGEVYLAYSPAGDPVAVKLIRGDRLDPVTRARFEKEALIARTVVGTNRVARFLDADPYADRPWLAMEYAPGDTLFVHVEAHGPLPAPLVASLGALLAEGLEAVHATGLLHRDLKPQNVIMGDYGPLLIDFGLGAFLDAAKDTLSHSGMIIGTVRCMPPEQAMGRPQVTPAADVYGLGTILLYAATGHFPYEGGRWEAIVGRVANPLDCPDLAGLPAVLDPLVSSMLAHEPTDRPSLKAVTATCAKLMHDDGLSPVRARQALIDRTAPNLSATAAPPPPSVILDQIEATAGPLIGEGLDSPLDAPHEASDAAWENEVSSVVEQAAVAPPARVRGGRVPASQRVAEELRNQYKTQPGL
>CP025990.1|AUS81161.1|6216169_6217492_+|hypothetical-protein
MLLHHDDDERARYRELPASSSESEGDVLDEKAIQPGERLLWDLASRPPQDPAELLIHLDSFRTTLRERGARLVVVLNEDQLSQVSGESRPLLVTLGRPDGRAVLANHLRADEIPFSEAELNDPRLDSHFESDPMRQLAKLAQLVRDAQHRASADLPLGRLLGQALEALDGHGDDVAQQVRSNPSAHFRALLLAAALLEGARLEPVQHAATGLLAKLHYPPEETHVLERPDLAERLAAVGAVTKDGRVTGFSTLAYGSAVLTHFWRYFPELRREFRAWVDSTMRLQGLTGRDRDLVVTRFAEQCIRTEQQGDLFSLVRDWSDRGESRSSPFLLPQVGRALDHGLADQRAGWRFREQILRWSQNRTLPVDLAQVLIRLCVEAIVPDHPDQALVRLHHLTRHQEDNVVASASDALDARNHCGNTAHDLFPMTPENSAENSCTR

Crispr_ID: CP025990_44

• CRISPR_ID: CP025990_44
• CRISPR_location: 6577264-6577717
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas2,cas6e

Consensus repeat of CP025990_44

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR

spacers of CP025990_44

>44.1|6577292|32|CP025990|CRISPRCasFinder,CRT
GGCTGTCCGCACCGGCCGCCCCTGTGGACGAG
>44.2|6577352|33|CP025990|CRISPRCasFinder,CRT
GTCGAGGTGGTGGACCCGAACCAGCTTGGGCTC
>44.3|6577413|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
AGCGATTCGTTCAGCCGGATTTCCGACAGGAGC
>44.4|6577474|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
TCCGTACTGAGCGCCTTGACGGCGCGGATCTCA
>44.5|6577535|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
GATTCGGGCTGGGACAGCCTGGCTCCGGGGAAC
>44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
CGGCAGCTTCGACAGGACGTTGTTCCGGACCCA
>44.7|6577657|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
TCCCCTCCCGCTCCACCGGAGTTGCGCAGTGCC

CRISPR arrays and Neighbor proteins around CP025990_44

CRISPR arrays

The CRISPR arrays of CP025990_44

>merge|CP025990|44|6577264-6577717|CRISPRCasFinder,CRT,PILER-CR
CGAGCAGTCCCGCATGCGCGGGGAGACCGGCTGTCCGCACCGGCCGCCCCTGTGGACGAGGGAACCGCCCCGAGTGCGCGGGGAGGACGTCGAGGTGGTGGACCCGAACCAGCTTGGGCTCGGAACAGCCCCGCGTGCGCGGGGAGGACAGCGATTCGTTCAGCCGGATTTCCGACAGGAGCGGAACAGCCCCGCGTGCGCGGGGAGGACTCCGTACTGAGCGCCTTGACGGCGCGGATCTCAGGAACAGCCCCGCGTGCGCGGGGAGGACGATTCGGGCTGGGACAGCCTGGCTCCGGGGAACGGAACAGCCCCGCGTGCGCGGGGAGGACCGGCAGCTTCGACAGGACGTTGTTCCGGACCCAGGAACAGCCCCGCGTGCGCGGGGAGGACTCCCCTCCCGCTCCACCGGAGTTGCGCAGTGCCGGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|44|42|6577264-6577717|CRISPRCasFinder
CGAGCAGTCCCGCATGCGCGGGGAGACC	GGCTGTCCGCACCGGCCGCCCCTGTGGACGAG
GGAACCGCCCCGAGTGCGCGGGGAGGAC	GTCGAGGTGGTGGACCCGAACCAGCTTGGGCTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	AGCGATTCGTTCAGCCGGATTTCCGACAGGAGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCGTACTGAGCGCCTTGACGGCGCGGATCTCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GATTCGGGCTGGGACAGCCTGGCTCCGGGGAAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGGCAGCTTCGACAGGACGTTGTTCCGGACCCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCCCTCCCGCTCCACCGGAGTTGCGCAGTGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|44|35|6577264-6577717|CRT
CGAGCAGTCCCGCATGCGCGGGGAGACC	GGCTGTCCGCACCGGCCGCCCCTGTGGACGAG
GGAACCGCCCCGAGTGCGCGGGGAGGAC	GTCGAGGTGGTGGACCCGAACCAGCTTGGGCTC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	AGCGATTCGTTCAGCCGGATTTCCGACAGGAGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCGTACTGAGCGCCTTGACGGCGCGGATCTCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GATTCGGGCTGGGACAGCCTGGCTCCGGGGAAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGGCAGCTTCGACAGGACGTTGTTCCGGACCCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCCCTCCCGCTCCACCGGAGTTGCGCAGTGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|44|38|6577385-6577717|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	AGCGATTCGTTCAGCCGGATTTCCGACAGGAGC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCGTACTGAGCGCCTTGACGGCGCGGATCTCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GATTCGGGCTGGGACAGCCTGGCTCCGGGGAAC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CGGCAGCTTCGACAGGACGTTGTTCCGGACCCA
GGAACAGCCCCGCGTGCGCGGGGAGGAC	TCCCCTCCCGCTCCACCGGAGTTGCGCAGTGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81242.1|6580879_6581446_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|334450
CP025990.1|AUS81232.1|6549539_6552968_-|hypothetical-protein	unknown	unknown	gnl|CDD|187659
CP025990.1|AUS81240.1|6578503_6578959_-|glyoxalase	unknown	unknown	gnl|CDD|380093
CP025990.1|AUS81235.1|6571602_6571962_-|hypothetical-protein	unknown	unknown	gnl|CDD|214834
CP025990.1|AUS82053.1|6578005_6578395_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|132706
CP025990.1|AUS81231.1|6548624_6549041_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81234.1|6561427_6571357_-|polyketide-synthase	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS81230.1|6547972_6548605_-|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
CP025990.1|AUS81239.1|6576794_6576983_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81244.1|6581972_6582497_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81245.1|6582617_6583238_-|DNA-binding-protein	unknown	unknown	gnl|CDD|223340
CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
CP025990.1|AUS81241.1|6579957_6580575_-|polyketide-cyclase	unknown	unknown	gnl|CDD|176908
CP025990.1|AUS81233.1|6552925_6561421_-|hypothetical-protein	unknown	unknown	gnl|CDD|225858
CP025990.1|AUS81237.1|6573012_6575661_-|hypothetical-protein	unknown	unknown	gnl|CDD|187655
CP025990.1|AUS81246.1|6583234_6583906_-|transcriptional-regulator	unknown	unknown	gnl|CDD|224647
CP025990.1|AUS81243.1|6581505_6581976_+|transcriptional-regulator	unknown	unknown	gnl|CDD|224647
CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
CP025990.1|AUS81238.1|6576247_6576535_+|hypothetical-protein	unknown	unknown	gnl|CDD|198390
CP025990.1|AUS81236.1|6571940_6572984_-|hypothetical-protein	unknown	unknown	gnl|CDD|238429

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.2e-30	100.3	0.5
CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	2.2e-61	202.4	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81242.1|6580879_6581446_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	1.12345e-12
CP025990.1|AUS81232.1|6549539_6552968_-|hypothetical-protein	gnl|CDD|187659	cd08956, KR_3_FAS_SDR_x, beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 3, complex (x). Ketoreductase, a module of the multidomain polyketide synthase (PKS), has 2 subdomains, each corresponding to a SDR family monomer. The C-terminal subdomain catalyzes the NADPH-dependent reduction of the beta-carbonyl of a polyketide to a hydroxyl group, a step in the biosynthesis of polyketides, such as erythromycin. The N-terminal subdomain, an interdomain linker, is a truncated Rossmann fold which acts to stabilizes the catalytic subdomain. Unlike typical SDRs, the isolated domain does not oligomerize but is composed of 2 subdomains, each resembling an SDR monomer. The active site resembles that of typical SDRs, except that the usual positions of the catalytic Asn and Tyr are swapped, so that the canonical YXXXK motif changes to YXXXN. Modular PKSs are multifunctional structures in which the makeup recapitulates that found in (and may have evolved from) FAS. In some instances, such as porcine FAS, an enoyl reductase (ER) module is inserted between the sub-domains. Fatty acid synthesis occurs via the stepwise elongation of a chain (which is attached to acyl carrier protein, ACP) with 2-carbon units. Eukaryotic systems consists of large, multifunctional synthases (type I) while bacterial, type II systems, use single function proteins. Fungal fatty acid synthesis uses a dodecamer of 6 alpha and 6 beta subunits. In mammalian type FAS cycles, ketoacyl synthase forms acetoacetyl-ACP which is reduced by the NADP-dependent beta-KR, forming beta-hydroxyacyl-ACP, which is in turn dehydrated by dehydratase to a beta-enoyl intermediate, which is reduced by NADP-dependent beta- ER. Polyketide synthesis also proceeds via the addition of 2-carbon units as in fatty acid synthesis. The complex SDR NADP-binding motif, GGXGXXG, is often present, but is not strictly conserved in each instance of the module. This subfamily includes KR domains found in many multidomain PKSs, including six of seven Sorangium cellulosum PKSs (encoded by spiDEFGHIJ) which participate in the synthesis of the polyketide scaffold of the cytotoxic spiroketal polyketide spirangien. These seven PKSs have either a single PKS module (SpiF), two PKR modules (SpiD,-E,-I,-J), or three PKS modules (SpiG,-H). This subfamily includes the second KR domains of SpiE,-G, I, and -J, both KR domains of SpiD, and the third KR domain of SpiH. The single KR domain of SpiF, the first and second KR domains of SpiH, the first KR domains of SpiE,-G,- I, and -J, and the third KR domain of SpiG, belong to a different KR_FAS_SDR subfamily. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type KRs have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.40778e-156
CP025990.1|AUS81240.1|6578503_6578959_-|glyoxalase	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	4.45021e-26
CP025990.1|AUS81235.1|6571602_6571962_-|hypothetical-protein	gnl|CDD|214834	smart00823, PKS_PP, Phosphopantetheine attachment site. Phosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups.	1.01039e-09
CP025990.1|AUS82053.1|6578005_6578395_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|132706	TIGR03667, Rv3369, PPOX class probable F420-dependent enzyme, Rv3369 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	2.6395e-30
CP025990.1|AUS81234.1|6561427_6571357_-|polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS81230.1|6547972_6548605_-|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	5.02444e-12
CP025990.1|AUS81245.1|6582617_6583238_-|DNA-binding-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	1.05165e-19
CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.01782e-40
CP025990.1|AUS81241.1|6579957_6580575_-|polyketide-cyclase	gnl|CDD|176908	cd08899, SRPBCC_CalC_Aha1-like_6, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	4.33238e-29
CP025990.1|AUS81233.1|6552925_6561421_-|hypothetical-protein	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP025990.1|AUS81237.1|6573012_6575661_-|hypothetical-protein	gnl|CDD|187655	cd08952, KR_1_SDR_x, ketoreductase (KR), subgroup 1, complex (x) SDRs. Ketoreductase, a module of the multidomain polyketide synthase (PKS), has 2 subdomains, each corresponding to a SDR family monomer. The C-terminal subdomain catalyzes the NADPH-dependent reduction of the beta-carbonyl of a polyketide to a hydroxyl group, a step in the biosynthesis of polyketides, such as erythromycin. The N-terminal subdomain, an interdomain linker, is a truncated Rossmann fold which acts to stabilizes the catalytic subdomain. Unlike typical SDRs, the isolated domain does not oligomerize but is composed of 2 subdomains, each resembling an SDR monomer. The active site resembles that of typical SDRs, except that the usual positions of the catalytic Asn and Tyr are swapped, so that the canonical YXXXK motif changes to YXXXN. Modular PKSs are multifunctional structures in which the makeup recapitulates that found in (and may have evolved from) FAS. Polyketide synthesis also proceeds via the addition of 2-carbon units as in fatty acid synthesis. The complex SDR NADP-binding motif, GGXGXXG, is often present, but is not strictly conserved in each instance of the module. This subfamily includes KR domains found in many multidomain PKSs, including six of seven Sorangium cellulosum PKSs (encoded by spiDEFGHIJ) which participate in the synthesis of the polyketide scaffold of the cytotoxic spiroketal polyketide spirangien. These seven PKSs have either a single PKS module (SpiF), two PKR modules (SpiD,-E,-I,-J), or three PKS modules (SpiG,-H). This subfamily includes the single KR domain of SpiF, the first KR domains of SpiE,-G,H,-I,and #J, the third KR domain of SpiG, and the second KR domain of SpiH. The second KR domains of SpiE,-G, I, and #J, and the KR domains of SpiD, belong to a different KR_FAS_SDR subfamily. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type KRs have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	0
CP025990.1|AUS81246.1|6583234_6583906_-|transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	9.86335e-27
CP025990.1|AUS81243.1|6581505_6581976_+|transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.2947e-33
CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.23261e-72
CP025990.1|AUS81238.1|6576247_6576535_+|hypothetical-protein	gnl|CDD|198390	cd10443, GIY-YIG_HE_Tlr8p_PBC-V_like, GIY-YIG domain of uncharacterized hypothetical protein found in phycodnavirus PBCV-1 DNA virus, T. thermophila Tlr element eoncoding protein Tlr8p, and similar proteins found in bacteria. The family includes a group of diverse uncharacterized hypothetical proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI. Similar to I-TevI, family members from phycodnavirus PBCV-1 DNA virus have nuclease-associated modular DNA-binding domains (NUMODs) and a helix-turn-helix (HTH) domain C-terminally fused to the GIY-YIG domain, which suggests that these PBCV-1 acquired the I-TevI-like homing endonucleases from phages by horizontal gene transfer. This family also includes proteins that appear to connect homing endonucleases with Penelope elements, such as Tetrahymena thermophila Tlr element encoding protein Tlr8p that possess additional N-terminal and central structural regions, followed by a putative superfamily 1 helicase domain and I-TevI-like GIY-YIG domain, but lacks the NUMOD domains and HTH domain. It is suggested that the Tlr8p element could have acquired its GIY-YIG domain w ithin the nucleus of the ciliate cell infected by the Phycodnavirus. Some family members only contain a standalone GIY-YIG domain and their biological functions are unclear.	1.32624e-11
CP025990.1|AUS81236.1|6571940_6572984_-|hypothetical-protein	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	2.21737e-78

Protein sequences

>CP025990.1|AUS81239.1|6576794_6576983_-|hypothetical-protein
MTLFEPPNCQRRSCLRRWTWLWCVPALVLLVLIIPLTVAVWGDSSPCDEGFRSLGPQVCVRE
>CP025990.1|AUS81238.1|6576247_6576535_+|hypothetical-protein
MRTQVVYKITYPNGKIYVGSDVTGTVTYFGSVNDELVAADHTPEQLRDFTVRKQVLWESPTAEPTEVRARERQYIETLQSNNPDIGYNRTPKFRG
>CP025990.1|AUS81237.1|6573012_6575661_-|hypothetical-protein
MRYAITQNTAQFLARYQQFELRWDQVEALRLVAWVCHHSRALPMASEDLVQSAGHDVLSEHLLSLWGERLGSARSREAGSQAWFLAALSDFNQQIQARDIVFFLKEAAEKSADDPVPTKWTDRLLTPMSMRRALPACSRQKIEAIPAPPPRPASSPPSSPLLLVGTGRRPDGTLGTGRGGSRHARGPGLGAPPGGAGWSGRHPRWGPLSITAGHAPPPRRRPGPGRFAHASPAAGNLRPRDEERAHREVDARRRRALAGVHGSCGTVPLPTYAFQHRDYWVDPTTRAPSGATTEEARFWAAIEREDIDELAATLQVDGAEGQASLSAAVEMLSAWRQRVRSDAAIDDLCYDVTWKPLPADPDEAVSGTWLVVSSDGQADDETVRACVDGLREHGARVETIGVASASTRGELTALLRVLAADDEIRGVLSTVALDERGGAAGVPVGVELTVLLIQALGDAGIQAPLWCASQGAVSTTRSDLLRKPVQALVWGVGRVAALEHPRTWGGLVDLPETVDDLALARLCGVLAGRTGEDQVAVRGSGVLARRLTRAAPKGRPVRSWRPRGTILVTGGTGALGSEVARWLAHAGAEHLVLTSRRGLAARGAATLRDELVELGARVTVAACDVADRDALAELLDTVPEEYPLTAVMHVAGVLDDGVLDSLTPERFGAVLRPKLGAALALHELTRELDLSAFVLFSSDTGTVGSAGQGNYAAGNAFLDALAEWRRAHGLPATAVAWGPWASVGMASDGAAKERLGKRGLSPIAPEVAITALRRVLDHDETTVVIADVLWEAFCASFTSVRDSRLFERIPEARQAMESDAAPAPGQPDEESFLGRLSGLSVVEREEWLLAWVCGVAGRAGWSGPVPAWPGVGGSVVGVGVVG
>CP025990.1|AUS81236.1|6571940_6572984_-|hypothetical-protein
MAGAGFPALTVEQGLALFDAAWGVDRSVVVPVVLDLPRLRTRGVPPMLRGLVRTPTRRAAPGDAGLVAELMSLGSDERVATVLNLVRTHVVAVLGHATNDAVQPHHAFSDLGFDSLTAVELRNRLNAVTGLRLPATLVFDYPTPAVLAEFVVGELVGTRAAVETVVATGVGTDEPIAIVGMSCRYPGGVSNPDELWDLVAAGGDAIGPFPQDRGWDVDGFGGFLADAAEFDPAFFGISPREALAMDPQQRLLLEASWEAFERAGVDPTGLKGSRTGVFAGLMYHDYVSESSTVPDGVEAFLGMGNAGSVLSGRVAYTFGFEGPTLTVDTACSSSLVALHLAWSCGVG
>CP025990.1|AUS81235.1|6571602_6571962_-|hypothetical-protein
MELRGRLTAVTGLSLPATLVFDYPTPEAVVEYLRQTDLVAGGDDTAGLLAELDKLEAGLAGTAPDELTRAKVAVRLQAFLAKWTGETPQVTGPGVVDQLEDASDDEILSFINDELGRAT
>CP025990.1|AUS81234.1|6561427_6571357_-|polyketide-synthase
MANEETLRDYLKWVSAELHQTRQRVRELEAGDREPIAIVAMACRFPGGVRTPEDLWRLVVAGTDAITPFPQDRGWTVPPGLSTSGEGGFLTDVADFDAAFFGISPREAVAMDPQQRLLLEVAWETLERAGIDPESLRGTNTGVFTGTASQDYVGVLRQAPEGSEGHTLTGNAASIVSGRIAYSLGLEGAAVSVDTACSTSLVALHLAAAALRKEECGLALAGGASVMSTPTAFLGFDDQGGLAADGRCKPFSAAADGTSWGEGAAFVLLERLADARRNGHPVLAVLRGSAVNSDGASNGLTAPNGPAQQRVILRALADARLAPSEVDAVEAHGTGTVLGDPIEAQALLATYGQDRERPLLLGSVKSNIGHTQAAAGMAGVIKMVQAMHHGMLPRTLHLDTPTPHVDWSAGAVTLLGEETTWPVTGRPRRVGVSSFGMSGTNAHVILEQAPDEELPGGTGGIPPVSPWVLSGRSAAALRAQEERLLEFVADTDARPVDIGAALTTRTSFEHRAVVFDREQLTGLGSGAVRGSASAGLTAVLFTGQGSQRPGMGRELTEAFPVFAEAFDAVCAELDRHLDRPIRNTVFHDDGDAGVLDQTVYAQAGLFALQVALFRLIESWGVVPDSLLGHSIGELAAAHVAGVWDLPDAARVVAARGRLMQALPEGGAMVAVEATEDEVIPLVGAGVSLAAVNGPAAVVLSGERSAVAGVVDRLGDRRVRWLRVSHAFHSELMDPMLAEYRAVLASVVFREPVVPVVSTVTGALAGTGWCDPEYWVRQVRETVRFGAAVERTRELGVSRFLELGPDGVLSAMGQDCAPEGVFVPVLRRDRPEPETVVGALASLWVTGMPVDWAAYYGGCGARRVPLPTYAFQHRRFWPTTSDSASTPDSDPVDARFWDAVEREDRSALADLLAVEDTTPIEAALPALSSWRRRRRVDDTIGSWRYREVWRPIAVDTDPVLTGTWWIVTGPEQSGDQTAEALAGALTRRGATVVPLVVTGTDSALLAAQLGDAPRPDGILSFLALTADDAVPVPAGLAATDALVKAVGRTAPVWCLTRAAVSVGRSDEAPVPAQAMTWGYGRVAGVELARTWGGLIDLPRTCDERALTRVCGVLGGAEDQVAVRTSGVFARRLGRAARLDGPGEPWAPRGTVLITGATGAIGGHLARWLAREGADHLVLTSRRGADAPGAADLVEELAALGARTTIATCDVADRAALTDLLSALRGAGETITAVLHTAGVRQLTTIDDTGPDEFARIVTGKVLGAANLDAAFADDDLDAFILFSSISAVWGSGGQGAYAAGGAYLDALAARRRSAGLPATSVAWGVWDGGGMSDGEVGAALGRRGLSPMSPDLAVQALRQVVAHRETTVTVVDVDWERFAPAFTVARPSPLIGDLPEVRHVLDVGEIDTSGTSRLRTELEGLPARERAVAVLDLVRAEAGRALGYTDADELPADRAFRDLGLDSITAVDLRDRVSAATGLRLPTTLVFDHPTPAAVARHLLAETFGADTDGAAEVPAGVVGGTDDPVVIVGMSCRFPGGVRSPEQLWEMLTSGGDAIGEFPTDRGWDVDGLFGPDPDVPGTSYSTRGGFLDDATRFDAAFFGISPREAVAMDPQQRLLLELSWEALERAGIPPGSLRGSRTGVFVGASPQGYGNGVADLPDEVAGYLMTGTATAVLSGRVAYTLGLEGPALTVDTACSSSLAALHLAAQALRGGECERALVGGVAVMATPGTFVEFSRQRGLAADGRCKAFADSADGTGWSEGVGVLVVERLSTARAHHHEVLAVVRGSAINSDGASNGLSAPNGPSQSRVIRQALAAAQLEASQVDVVEGHGTGTTLGDPIEAQALLATYGRDRPADRPLRLGSVKSNLGHTQAAAGVAGVIKMVLAMRHGVLPRTLHVDQPSTRVDWSSGAVSLLTDQVDWPDTDEPRRAAVSSFGVSGTNVHTVLEQAPASHRAPSGDVRPPALTPWLVSGRTANALRAQAGRLAAHVSEGSGLDIAYSLATTRTHLEHRAVVLSEDHGGQVAALAALADGAQPADVVLGTPTTGGTAFLFAGQGAQRPAMGRELYDTYPVFADAFDEVCAHLDRHLDRPLADIVLTGEGLDRTRHTQPALFAVEVALFRLLHSWGVRPDVLLGHSVGELAAVHVAGVLSLSDAAALVATRARLMDALPEGGAMVSVRATEAEVRPLLSEHVSLAAVNGPTTVVVSGDEEAVAAVADHFATQGRRTRRLPVSHAFHSPRMRPMLDEYRAFAAGLPFAAPTIPIISTVTGAPVTTRELVDPDYWARQVSDPVRFLDAVLATRERGVTILVELGPDGTLTGLASHCLPDTEDLTLVPTLRPERAEPRTVVTALANIHAAGGTVDWAAYYARSGATHVPLPTYAFEPERFWLRSQAGPAGPPGLGTIGHPLLTGVVDEAHADAVLCTGSLSLATHPWLADHAVLGTVVFPGAGFVELALQAGAQARCPRLDELTIEAPLVLPAEGTVRLQVRAGPPDETGARPVTIHGREDDDQPWTRHAAGTLAPASPQRGRALAEWPPTGATPVPVDGFYDALVELGYGYGPVFQGLTSAWTHGGDVYADVTLPTEDGGGFGLHPALLDSALHGIGLADPDESTSSRLPFAWNGVTLHAPGASALRVRISRAVGDAVALTLADTAGGPVAEIESLVLRPVTGAQLGDASRSRQDSLFVLDWTAVDAPAEANAVTLLGSTLPDADLPRCAELADVASDAGNFAVVTQFASDGDVLTATHAVTSAALDFLLAWFADDGFDRTPLVVLTRGGVASGPDETVTDLAQAALWGLLRSAQLEHPGRLTIIDIDDTPESVAALPHAVASENPQLVLRGGQLRAPALNRKRGSGAEPAPVDPRGTVLVTGGSGVLAQLVARRMVARGARHLVLASRQGPAAPGAEDLAAELADLGAETRFVACDVSDRNEVASLLAGIRDEHPLRVVVHTAGVLDDGVLSSLTPGRIGTVLAPKADAAWHLHELTRSLDLSAFVLFSSTAATFGSPGQANYAAANAFLDALAHHRAAAGLPALSLGWGPWAESGMLGNLDAGGIARFARSGLVPLSTEQGAALFDAVDQADGPAVLVARPATSGAQVSIDLVPPLLRPLLPVSARPRTEVPATTASELRLRLSSASEEDRDRITYSVVVEAAAAVLGHSSPEAIERGRGFLDIGFDSLTAVELRNRLNAVTGLRLPATLVFDHPTPEDLAEHVRDELVENTSVSALWLVGELDRLATAFAAVPEGDDDRARVTERLRGLLSSWTEQGPAAEDPSGLADATADQIFDLLDEELGVAGPRPGPPTTSKE
>CP025990.1|AUS81233.1|6552925_6561421_-|hypothetical-protein
MANEEKFLDYLKRATADLRETRRRLREVEDRDAEPIAIIGMSCRYPGGITSPEDLWRLVANDGDGIGDFPTDRNWDIDRFFEADPDEAGASYVRGGGFLDGATRFDSSFFGISPREALAMDPQQRVLLEASWEVFERAGITPASVRGSRTGVFAGLMYHDYLPLIQSVPDGVEGYLGTGNSGSVLSGRVAYYFGLEGPAVTVDTACSSSLVALHLAAQALRRGECSMALAGGVTVMATPGTFIDFSRQRGLAFDGRCKSFAASADGTGWSEGVGVLLVMRLSDALERGHRVLAVVRGSAVNSDGASSGLTAPNGRSQQRVIRQALANARVAPEHVDVVEAHGTGTTLGDPIEAQALLATYGQDRAEERPLWLGSVKSNIGHTQAAAGAAGVIKMVMAMRHGVLPRTLHVDEPTPEVDWSAGAVSLLTEAVPWPEADRPRRAAVSSFGISGTNAHVIIEQAPPVSEPAERVAPSVVPWVLSAKSSEALDAQAVRLSAHLDDVTVDPLDVAHTLATARTSFEHRAVVFDREQLTGLGSGAVRGSASAGLTAVLFTGQGSQRPGMGRELAEAFPVFAEAFDAVCAELDRHLDRPIRDTVFHDDDGAGVLDQTVYAQAGLFALQVALFRLIESWGVVPDSLLGHSIGELAAAHVAGVWDLPDAARVVAARGRLMQALPEGGAMVAVEATEDEIIPLLVGAGVSLAAVNGPTAVVLSGERSAVAGVVDRLGDRRVRWLRVSHAFHSELMDPMMAEYRAVLSSVVFREPVVPVVSTVTGALAGTGWCDPEYWVRQVRETVRFGAAVERTRELGVSRFLELGPDGVLSAMGQDCAPEGVFVPVLRRDRPEPETVVGALASLWVTGMPVDWAAYLAETNARLVDLPTYAFQQEHYWPDTSTGWSGDVSAVGLRSADHPLLGTAVGVARTDEFLFTGRLSLESQPWLAGHVVGGSVLVPGTAFVELVLRAGEQAGCGVVDDLTLETPLLLPERGGVAVQVFVAAPDEDGHRAVTVHSCADDEEWVRHASGVVGAVVPPARALDVWPPENAASIDVEELYDGLQAAGLAYGPEFRGVRSLWRRDDEVFAEVVLPEGLSADGFGVHPALLDAALHGVALFDGEGGLPFAWSGVSVFAVGATTARVRISRAGSGFSLLLADGVGQPVAAVDSLVLRPFTAVPVSASGAESLYGIEWVPVSGEALTGDHQVVSLPPGGEVRERLAEALALVQDTDDDRVRVVVTRGATDGRDLTQAAVWGLVRTAQSENPGRFVLVDLDPDTDSDGVELPELVAGEPQLAVRDGRLLAPRLARVAPEPGEPLPEGGTVLVTGASGVLGGLVARHLVERYGVRHLVLLSRSGGDSGVGELDAEVRTVACDVADRDAVAEVVAGIGSEHPLVGVVHTAGVLDDAMVSSLTPERFDAVLRPKVEGAWNLHEVTRDLDLAMFVVFSSVAGVLGSPGQGNYAAANAFLDGLAQYRRGLGLAGQSLAWGLWAEGGMTADSRRLARAGYPPLTVEQGLALFDAALTSDRAALVPVNLDLSVLRSRAATEGVPPLLRSLVRVARRRIARGDAGLVGNLGGLKAEDRVRVVLDQVRGQVAAVLGHTSGDAVQPRQSFTDLGFDSLTAVELRNRLNAVTGLRLPATLVFDYPTPADLAEFVLDELNGSASLAVAPAPTVVGTDEPIAIVGMSCRYPGGVSSPDELWDLVAAGGDAIGAFPTDRGWGLEGAGGFLHDAAEFDPGFFGISPREALAMDPQQRLLLEASWEAFEHAGIDPTGLKGSRTGVFAGLMYHDYLSESSTVPDGVEAFLGMGNAGSVLSGRVAYTFGFEGPTLTVDTACSSSLVALHLAVQALRSGECSMALAGGVTVMATPATFAEFSRQGGLSFDGRCKSFAQAADGTGWSEGVGVLLVEKLSDARRLGHPVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARVAPEHVDVVEAHGTGTTLGDPIEAQALLATYGRDRDRALLLGSVKSNLGHTQAAAGVAGVIKMVQAMRHGVVPATLHVDEPSREVDWESGAVDLVREPVSWPETGRARRAGVSSFGISGTNAHVILEGVELGDEPAPAQALPVTPWVVSAKSEQALTAQVDRIRAHVETTGADPVDVGYSLATGRAVFEHRAVLVGEEVVQGSAAPGRLAVLFTGQGSQRPGMGRELAEAFPVFAEAFDAACAELDRHLDRPIRNVVFHDDDGAGVLDRTVYAQAGLFALQVALFRLIESWGVVPDSLLGHSIGELAAAHVAGVWDLPDAARVVAARGRLMQALPEGGAMVAVEATEDEVIPLVRAGVSLAAVNGPTAVVLSGERSAVAGVVDRLGDRRVRWLRVSHAFHSGLMDPMMAEYRAVLSSVVFREPVVPVVSTVTGALAGTGWCDPEYWVRQVRETVRFAEGMAALGGVGVSRFLELGPDGVLSAMGQDCAPEGVFVPVLRRDRPEPETVVGALARVFVHGTEVDWAGYYGGCGARRVPLPTYAFQHERYWPRAGLGTGFGSLGHSMLGTGVVLAGDEGVMLSGVLSAADLPWLSEHVVLGSVMVPGAALVEAVLFAGERVGCDLLDELTLQVPLLLPEHGAVTVQVFVSGPDDEGRRTVTVHSRADENGEWARHATGVLSTGSPTPGQVLTVWPPERATEVDVTDLYDRLDEAGLSYGPVFQGLRRAWRLGEDEVFAEVALPVDVAVDGFGVHPALLDAALHGIGLLGGEGALPFAWSEVSISAVGASSLRVRICRAGSGFSLLLADGAGQPVASIGALSLRAPSVDRSTTSPHRNALFGVDWVPVSGEALTGDHQVVSLPPGGEVRDGCGGCGSATPSTPG
>CP025990.1|AUS81232.1|6549539_6552968_-|hypothetical-protein
MRWLRVSHAFHSGLMDPMLAEYRAVLSSVVFREPVVPVVSTVTGALAGTGWCDPEYWVRQVRETVRFAEGMAALGGVGVSRFLELGPDGVLSAMGQDCAPEGVFVPVLRRDRPEPETVVGALARVFVHGTEVDWAGYYGGCGARRVPLPTYAFQHERYWLRSTGRAASDPSSLGLDAGAHPLLGALVGSARTDEFLFTGSFSRETHPWLTEHEVLGTALLPGTAFVELALHAGQRLDCPILEELTLHAPLVLPVRGTVTVQLAAAAANSDGRRAVDVYSRTGDDEWSHHATGTLRPGTAVSGQALVTWPPTDAEPITVEDLYDRLAEWGLSYGPTFRGLAAAWSQGDEVYADVRLPEGVSVDGFGLHPALWDAALHGMALTGGNDTVALPFSWSDVSLSAVGASALRVRITPSTRGTSLTLADETGQPVAEVGSLAVRPVTGEVPSANAGNAMFAVDWEATSRAEVDPTLRWGAWGEHAEEAPDIVTLVVQDTGRDVVANTHTAVHEVLEIVRQWVSDERYADARLVVVTRGATDGGSPTSAAVWGLVRSAQSEYPGRLVLVDADEDTPNRAHLEEAVATGEPQVAVRSGELRVPRLVRVSATPAETTIDPAGTVLVTGASGALGARVARHLVAEHGVRHLLLVSRGGGVPTELSDLDADVRTAACDVTDRDALARVLTDVPPEHPLVGVVHAAGVLDDGVITSLTPARVDTVLSPKVDGAWHLHELTRELDLSLFVVFSSVAGVLGSPGQGNYAAANAFLDALAQHRRDLGLPGQSLAWGPWAEGGMLGTLSDADLRRMARTGIPALDGDEGLALFDTALGLDHAALAPVRLDLPVWRERAATDGVPPLLRRLVRTARRQVASRGDERGDLAVRLSGLPDEDRRAAVLTLVRAQVAAVLGHQSGDDVVPHHAFSDIGFDSLTAVELRNRLNTATGLRLPATLIFDYPSPDVLTDFVLAEVLDLRVDAPEVTPAVVSGLDEPIAIVGMACRYPGGVSNPDELWDFVRNGGDGITPFPADRGWHLDTVYGGEGEDRSTVLEGGFLHDAPWFDPGFFGISPREALAMDPQQRLLLEASWEAFENAGIDPGSLRGSRTGVFAGVMYNDYSAKVAEVPDGVEAFLGMGNAGSVLSGRVAYTCGRIV
>CP025990.1|AUS81231.1|6548624_6549041_-|hypothetical-protein
MSGSYEVDPEALPRAIAELKEALDCVLDLQTVATRMGMDKPSRGDDAVSLNAGDQFRELAASPQSGSLGRTAMQLRDELMQTIHHFESMLAEYLNLEDTATLPQYEGDITSFKNSPTYQEIAAAANRARAAAGGYIPI
>CP025990.1|AUS81230.1|6547972_6548605_-|DUF3558-domain-containing-protein
MTSRHLKIVLGLMAPLALLLTACADVSTEDSTSSAEETSVVSSTPGETAGSDENQSQLAPPVSAPVDAAGLEPCELMSDGAATSAGYDPDSKELRPNHSLDEAPLDMCRWLSNDVGSVTLNASSVPEGLSTVYANYSNYVVFEPRTVGEYPAVHTNDVEDSARCPLFVGIADDQVLLVDALTGPTDDACQIATEVAQAIMNELPPAAQEQ
>CP025990.1|AUS82053.1|6578005_6578395_+|pyridoxamine-5'-phosphate-oxidase
MEGLSEKAEDRVLWLGTVTPSNRPALRPVWFVYLEEKLVVFSEPHAAKVRHLFANPEVVMTFHSDPSAGHIRVVSGRAEVSLDGPPPSSIPEFLDKYEHLYPATGYTRHTFDAALSARITITPTHSWGW
>CP025990.1|AUS81240.1|6578503_6578959_-|glyoxalase
MEMTVQLTIDCSDPPRMVTFWAEALGYVPEPPPAGHATWRAYWAATGVPESELPAGAGDGPESIVDPTGRGPRVWFQQVPEPKVGKNRWHLDLKVSGGRDVPLEVRAQRVKAAVERLVTAGATLLRIKDGPHMGLYTAAMRDPEGNEFDVA
>CP025990.1|AUS81241.1|6579957_6580575_-|polyketide-cyclase
MDLLDHINRTHRAVKRGTEMNSVILTRAYDTTLPDLWDACVNPERLPRWFEPVSGDLREGGRYRLEGRGIEGTIEVCVPRERLRVTWEDSGAGSFVEVSLREEGDQAVLRVEHVQAGGDFWNTFGPSATGVGWDGSVLSLALHLAGDPRATPEEMAKVGASEEGVEFMRRTAAAWADADVEAGADPDHARQTSDRTFAFYTGAEQ
>CP025990.1|AUS81242.1|6580879_6581446_-|pyridoxamine-5'-phosphate-oxidase
METDIPADDAADLVSWEEGGGPPSRTEPLFGPSDASPFDAQAPLTPWSEAERRLAAASTVWLVTTRPDGRPHAVPVFAVWVDGALFVTLRPGSRKGRNLAVNPQVSVIVSSDELELVLEGRAERVREVRGLRRVGDALAGRFGWRLAVADDGVVTDPDLPGEPEYGIYGVVPRVSFGFAEVSATRWSW
>CP025990.1|AUS81243.1|6581505_6581976_+|transcriptional-regulator
MQRTRFGDMPCSIARTWNVIGEPWSPLILRDIYVGVRRFDDLQASLGISRKVLAERLAWLVDQQVLDRHPYTNRPTRHEYVLTPRGAELCDALLVLAGWGDRWLAGEDGPPALFRHRSCGEASNVTLHCSQCDQPMTAADVDVLDGPGAPAREETP
>CP025990.1|AUS81244.1|6581972_6582497_+|hypothetical-protein
MTTPARATLIGRDAPPGSTPIPWEEARDRFATASTYWWSTASGDHPTLRPVLSVWVDGAPHVSTSPATRKSRPLDTNPTTTLACQTDIADTVVEGTTSRVTDRATLHAVATAYATKYGWSPSVLGDALGGAEGAPTAGQPPYEVYRITPRRAYAFGTDEDHGARSTRWVFPDHS
>CP025990.1|AUS81245.1|6582617_6583238_-|DNA-binding-protein
MSKVVVDISMSLDGFVTGPNAGPDQGLGEGGEPIHRWVMPEEPSPEDSALLDAAFGATGAVVMGRRTFDVIDGAAGWKDDLGYGYEQDQSQAPPNFVVTHEPPANPRHQTGFTFVTEGVAAAVAAAREVAGERETVIMGGGDVCAQALALNLVDELRIHLSPVLMGSGTPLFAHIDQRVLLSQSTVTVTPNATHLTYQLPRDERGA
>CP025990.1|AUS81246.1|6583234_6583906_-|transcriptional-regulator
MRTYGDACGITRALDAVGERWALPVVRELVFGPRRYSDLAAALPGVSTNILGTRLRELAEVGVVVRRRLPPPTPVAVYELTAWGRALEPVLIALGRWAAHTPVDLAAQVLSPSSFALALRTTFDASLAGERAVAVRLEMGEDVFDTRIEEGAFQIARATPASRPPAARVAATPVVLSDLTFGSLAVEDAERRQLAVVSGPHADVKSLLSCFVLPDPPTEEGHS
>CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVVVVTACPVGLRGHLTRWLLEISPGVFVGGITARVRTLLWGRVQEMVKTGRAIMVYNADTEQGLAFEVHGHEWTPVDHEGVQLMLRPAQRKRSAPKQRAGWSTASRRRRYGRGQKSE
>CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MHLTRFELNPARRATRHLLASPHRLHGAVMKAFPAAHREPTEDGRVLWRLDQTPNQTLLYIVSPHRPDLTHLVEETGWPATSTWDTRPYGPLLDQMAAGQEWAFRLTANPTRSVRRTSDADTKRYGHLTVTQQTDWLLGRVERLGFTIPPAVGDEPDVAIRGRDRRKFDRQGTTVTLTLATYEGRLRVADPALFRRTLTHGVGSAKGYGCGLLTLARVRPT

Crispr_ID: CP025990_45

• CRISPR_ID: CP025990_45
• CRISPR_location: 6584133-6584344
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas6e,cas5,cas7,cse2gr11

Consensus repeat of CP025990_45

Consensus_repeat	Method
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRISPRCasFinder
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CRT
GGAACAGCCCCGCGTGCGCGGGGAGGAC	PILER-CR

spacers of CP025990_45

>45.1|6584161|33|CP025990|CRISPRCasFinder,CRT
GTGCATGATCTCGGCGGCGCTGACGAGGTAGCC
>45.2|6584222|34|CP025990|CRISPRCasFinder,CRT,PILER-CR
CTCGGGCAGGTGTGCGTGCGAGGCGATCTCGCCC
>45.3|6584284|33|CP025990|CRISPRCasFinder,CRT,PILER-CR
GCGGATTCCACGCGGGAGTCAAGGGCCGCCCGG

CRISPR arrays and Neighbor proteins around CP025990_45

CRISPR arrays

The CRISPR arrays of CP025990_45

>merge|CP025990|45|6584133-6584344|CRISPRCasFinder,CRT,PILER-CR
TGAACAGCCCCACATGCGCGGGGAGGACGTGCATGATCTCGGCGGCGCTGACGAGGTAGCCGGAACAGCCCCGCGTGCGCGGGGAGGACCTCGGGCAGGTGTGCGTGCGAGGCGATCTCGCCCGGAACAGCCCCGCGTGCGCGGGGAGGACGCGGATTCCACGCGGGAGTCAAGGGCCGCCCGGGGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|45|43|6584133-6584344|CRISPRCasFinder
TGAACAGCCCCACATGCGCGGGGAGGAC	GTGCATGATCTCGGCGGCGCTGACGAGGTAGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CTCGGGCAGGTGTGCGTGCGAGGCGATCTCGCCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCGGATTCCACGCGGGAGTCAAGGGCCGCCCGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|45|36|6584133-6584344|CRT
TGAACAGCCCCACATGCGCGGGGAGGAC	GTGCATGATCTCGGCGGCGCTGACGAGGTAGCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CTCGGGCAGGTGTGCGTGCGAGGCGATCTCGCCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCGGATTCCACGCGGGAGTCAAGGGCCGCCCGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

>CP025990|45|39|6584194-6584344|PILER-CR
GGAACAGCCCCGCGTGCGCGGGGAGGAC	CTCGGGCAGGTGTGCGTGCGAGGCGATCTCGCCC
GGAACAGCCCCGCGTGCGCGGGGAGGAC	GCGGATTCCACGCGGGAGTCAAGGGCCGCCCGG
GGAACAGCCCCGCGTGCGCGGGGAGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81242.1|6580879_6581446_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|334450
CP025990.1|AUS81249.1|6587109_6588249_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
CP025990.1|AUS81240.1|6578503_6578959_-|glyoxalase	unknown	unknown	gnl|CDD|380093
CP025990.1|AUS81250.1|6588245_6588878_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
CP025990.1|AUS82053.1|6578005_6578395_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|132706
CP025990.1|AUS81252.1|6597609_6597831_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81253.1|6598554_6599031_-|4-hydroxybenzoyl-CoA-thioesterase	unknown	unknown	gnl|CDD|238329
CP025990.1|AUS81239.1|6576794_6576983_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81244.1|6581972_6582497_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81245.1|6582617_6583238_-|DNA-binding-protein	unknown	unknown	gnl|CDD|223340
CP025990.1|AUS81251.1|6596700_6597486_+|TIGR03084-family-protein	unknown	unknown	gnl|CDD|274423
CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
CP025990.1|AUS81243.1|6581505_6581976_+|transcriptional-regulator	unknown	unknown	gnl|CDD|224647
CP025990.1|AUS81254.1|6605520_6606492_+|DUF1702-domain-containing-protein	unknown	unknown	gnl|CDD|369650
CP025990.1|AUS81246.1|6583234_6583906_-|transcriptional-regulator	unknown	unknown	gnl|CDD|224647
CP025990.1|AUS81241.1|6579957_6580575_-|polyketide-cyclase	unknown	unknown	gnl|CDD|176908
CP025990.1|AUS81248.1|6586396_6587113_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|378243
CP025990.1|AUS81238.1|6576247_6576535_+|hypothetical-protein	unknown	unknown	gnl|CDD|198390
CP025990.1|AUS82055.1|6597982_6598459_-|flavin-reductase	unknown	unknown	gnl|CDD|214900

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS81248.1|6586396_6587113_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	5.7e-44	144.8	1.4
CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.2e-30	100.3	0.5
CP025990.1|AUS81249.1|6587109_6588249_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.5e-118	391.2	3.3
CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	2.2e-61	202.4	0.2
CP025990.1|AUS81250.1|6588245_6588878_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	1.6e-29	97.6	1.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81242.1|6580879_6581446_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	1.12345e-12
CP025990.1|AUS81249.1|6587109_6588249_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	7.25665e-165
CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.23261e-72
CP025990.1|AUS81240.1|6578503_6578959_-|glyoxalase	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	4.45021e-26
CP025990.1|AUS81250.1|6588245_6588878_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	4.52698e-33
CP025990.1|AUS82053.1|6578005_6578395_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|132706	TIGR03667, Rv3369, PPOX class probable F420-dependent enzyme, Rv3369 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	2.6395e-30
CP025990.1|AUS81253.1|6598554_6599031_-|4-hydroxybenzoyl-CoA-thioesterase	gnl|CDD|238329	cd00586, 4HBT, 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites. There is no evidence to suggest that 4HBT is related to the type I thioesterases functioning in primary or secondary metabolic pathways. Each subunit of the 4HBT tetramer adopts a so-called hot-dog fold similar to those of beta-hydroxydecanoyl-ACP dehydratase, (R)-specific enoyl-CoA hydratase, and type II, thioesterase (TEII).	1.48616e-18
CP025990.1|AUS81245.1|6582617_6583238_-|DNA-binding-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	1.05165e-19
CP025990.1|AUS81251.1|6596700_6597486_+|TIGR03084-family-protein	gnl|CDD|274423	TIGR03084, conserved_hypothetical_protein, TIGR03084 family protein. This family, like pfam07398, belongs to the larger set of probable enzymes modeled by TIGRFAMs family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized. [Hypothetical proteins, Conserved].	1.02136e-103
CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.01782e-40
CP025990.1|AUS81241.1|6579957_6580575_-|polyketide-cyclase	gnl|CDD|176908	cd08899, SRPBCC_CalC_Aha1-like_6, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	4.33238e-29
CP025990.1|AUS81254.1|6605520_6606492_+|DUF1702-domain-containing-protein	gnl|CDD|369650	pfam08012, DUF1702, Protein of unknown function (DUF1702). This family of proteins contains many bacterial proteins that are encoded by the UnbL gene. The function of these proteins is unknown.	4.9817e-150
CP025990.1|AUS81246.1|6583234_6583906_-|transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	9.86335e-27
CP025990.1|AUS81243.1|6581505_6581976_+|transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.2947e-33
CP025990.1|AUS81248.1|6586396_6587113_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	5.80433e-40
CP025990.1|AUS81238.1|6576247_6576535_+|hypothetical-protein	gnl|CDD|198390	cd10443, GIY-YIG_HE_Tlr8p_PBC-V_like, GIY-YIG domain of uncharacterized hypothetical protein found in phycodnavirus PBCV-1 DNA virus, T. thermophila Tlr element eoncoding protein Tlr8p, and similar proteins found in bacteria. The family includes a group of diverse uncharacterized hypothetical proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI. Similar to I-TevI, family members from phycodnavirus PBCV-1 DNA virus have nuclease-associated modular DNA-binding domains (NUMODs) and a helix-turn-helix (HTH) domain C-terminally fused to the GIY-YIG domain, which suggests that these PBCV-1 acquired the I-TevI-like homing endonucleases from phages by horizontal gene transfer. This family also includes proteins that appear to connect homing endonucleases with Penelope elements, such as Tetrahymena thermophila Tlr element encoding protein Tlr8p that possess additional N-terminal and central structural regions, followed by a putative superfamily 1 helicase domain and I-TevI-like GIY-YIG domain, but lacks the NUMOD domains and HTH domain. It is suggested that the Tlr8p element could have acquired its GIY-YIG domain w ithin the nucleus of the ciliate cell infected by the Phycodnavirus. Some family members only contain a standalone GIY-YIG domain and their biological functions are unclear.	1.32624e-11
CP025990.1|AUS82055.1|6597982_6598459_-|flavin-reductase	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	1.61144e-46

Protein sequences

>CP025990.1|AUS81246.1|6583234_6583906_-|transcriptional-regulator
MRTYGDACGITRALDAVGERWALPVVRELVFGPRRYSDLAAALPGVSTNILGTRLRELAEVGVVVRRRLPPPTPVAVYELTAWGRALEPVLIALGRWAAHTPVDLAAQVLSPSSFALALRTTFDASLAGERAVAVRLEMGEDVFDTRIEEGAFQIARATPASRPPAARVAATPVVLSDLTFGSLAVEDAERRQLAVVSGPHADVKSLLSCFVLPDPPTEEGHS
>CP025990.1|AUS81245.1|6582617_6583238_-|DNA-binding-protein
MSKVVVDISMSLDGFVTGPNAGPDQGLGEGGEPIHRWVMPEEPSPEDSALLDAAFGATGAVVMGRRTFDVIDGAAGWKDDLGYGYEQDQSQAPPNFVVTHEPPANPRHQTGFTFVTEGVAAAVAAAREVAGERETVIMGGGDVCAQALALNLVDELRIHLSPVLMGSGTPLFAHIDQRVLLSQSTVTVTPNATHLTYQLPRDERGA
>CP025990.1|AUS81244.1|6581972_6582497_+|hypothetical-protein
MTTPARATLIGRDAPPGSTPIPWEEARDRFATASTYWWSTASGDHPTLRPVLSVWVDGAPHVSTSPATRKSRPLDTNPTTTLACQTDIADTVVEGTTSRVTDRATLHAVATAYATKYGWSPSVLGDALGGAEGAPTAGQPPYEVYRITPRRAYAFGTDEDHGARSTRWVFPDHS
>CP025990.1|AUS81243.1|6581505_6581976_+|transcriptional-regulator
MQRTRFGDMPCSIARTWNVIGEPWSPLILRDIYVGVRRFDDLQASLGISRKVLAERLAWLVDQQVLDRHPYTNRPTRHEYVLTPRGAELCDALLVLAGWGDRWLAGEDGPPALFRHRSCGEASNVTLHCSQCDQPMTAADVDVLDGPGAPAREETP
>CP025990.1|AUS81242.1|6580879_6581446_-|pyridoxamine-5'-phosphate-oxidase
METDIPADDAADLVSWEEGGGPPSRTEPLFGPSDASPFDAQAPLTPWSEAERRLAAASTVWLVTTRPDGRPHAVPVFAVWVDGALFVTLRPGSRKGRNLAVNPQVSVIVSSDELELVLEGRAERVREVRGLRRVGDALAGRFGWRLAVADDGVVTDPDLPGEPEYGIYGVVPRVSFGFAEVSATRWSW
>CP025990.1|AUS81241.1|6579957_6580575_-|polyketide-cyclase
MDLLDHINRTHRAVKRGTEMNSVILTRAYDTTLPDLWDACVNPERLPRWFEPVSGDLREGGRYRLEGRGIEGTIEVCVPRERLRVTWEDSGAGSFVEVSLREEGDQAVLRVEHVQAGGDFWNTFGPSATGVGWDGSVLSLALHLAGDPRATPEEMAKVGASEEGVEFMRRTAAAWADADVEAGADPDHARQTSDRTFAFYTGAEQ
>CP025990.1|AUS81240.1|6578503_6578959_-|glyoxalase
MEMTVQLTIDCSDPPRMVTFWAEALGYVPEPPPAGHATWRAYWAATGVPESELPAGAGDGPESIVDPTGRGPRVWFQQVPEPKVGKNRWHLDLKVSGGRDVPLEVRAQRVKAAVERLVTAGATLLRIKDGPHMGLYTAAMRDPEGNEFDVA
>CP025990.1|AUS82053.1|6578005_6578395_+|pyridoxamine-5'-phosphate-oxidase
MEGLSEKAEDRVLWLGTVTPSNRPALRPVWFVYLEEKLVVFSEPHAAKVRHLFANPEVVMTFHSDPSAGHIRVVSGRAEVSLDGPPPSSIPEFLDKYEHLYPATGYTRHTFDAALSARITITPTHSWGW
>CP025990.1|AUS81239.1|6576794_6576983_-|hypothetical-protein
MTLFEPPNCQRRSCLRRWTWLWCVPALVLLVLIIPLTVAVWGDSSPCDEGFRSLGPQVCVRE
>CP025990.1|AUS81238.1|6576247_6576535_+|hypothetical-protein
MRTQVVYKITYPNGKIYVGSDVTGTVTYFGSVNDELVAADHTPEQLRDFTVRKQVLWESPTAEPTEVRARERQYIETLQSNNPDIGYNRTPKFRG
>CP025990.1|AUS82054.1|6584384_6584744_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVVVVTACPVGLRGHLTRWLLEISPGVFVGGITARVRTLLWGRVQEMVKTGRAIMVYNADTEQGLAFEVHGHEWTPVDHEGVQLMLRPAQRKRSAPKQRAGWSTASRRRRYGRGQKSE
>CP025990.1|AUS81247.1|6585731_6586397_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MHLTRFELNPARRATRHLLASPHRLHGAVMKAFPAAHREPTEDGRVLWRLDQTPNQTLLYIVSPHRPDLTHLVEETGWPATSTWDTRPYGPLLDQMAAGQEWAFRLTANPTRSVRRTSDADTKRYGHLTVTQQTDWLLGRVERLGFTIPPAVGDEPDVAIRGRDRRKFDRQGTTVTLTLATYEGRLRVADPALFRRTLTHGVGSAKGYGCGLLTLARVRPT
>CP025990.1|AUS81248.1|6586396_6587113_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTALVLRFAAPLQSWGTSSRFTRRNTDLAPSRSGVIGLLASACGVRRADDLGAFTHLRVGVRVDQEGQLERDFQTARSLDGSQVMPLSTRFYLADAVFCVAVEGDAELLDRVRAALRRPAAPLFLGRRSCPPAGRLVEAVIDGDIRTALATVPWLASPAVRRKRASDREVTVDVVLDCPPDTPGSDVVRDVPISFDPRHRQYSWRSVHRDTVTIPNPDHRPPPDEHPHDPMELLGSPS
>CP025990.1|AUS81249.1|6587109_6588249_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSRTIIDLHVIQTVPPSNINRDDTGSPKTAMYGGVRRARVSSQAWKRATRVAFESLLDKENLGVRTKRIVDLVAETIGERSPGHADRAQELAKSVLEAAGFKLKAPRKKATEATPDEAEFLVFLARAQITNLADLAVESAREAGDGKTKIDKSEAKARADRSHSVDVALFGRMVANLPDLNVEAATQVAHALSVHGVTNEYDYYTAVDDHKKADEEEDAGAGMIGTIEFNSSTLYRYATIDVDQLQENLGDVEATRRAVEAFVRAFVSSMPTGKQNTFANRTLPDAVLVVARETQPINLVGAFEEAVTAREQGGRISGSIRRIATHATDIHAAFDETPLRAWSFGVGERVEPLAEIGERVSLDVAVKGAGQLVAERLAP
>CP025990.1|AUS81250.1|6588245_6588878_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTGNHSEPPPLRKWVNEQTGRLQQEYIQDRSHAVAGLARLRRAVDTAPGVMPDILDLTYAPFMTQGWHSDQPSARETAAHHAMTLFAVHQQSLRKHACVPGWGVGRAARALHPQAEISPIDPAARRFATLVTSTDLDELLVHLRGLVKLLRAAEIPLDYGLLADQLVRWQRFEDAPERIRRVWGREFHRVPNTESDTTPPSDNEKTEDAS
>CP025990.1|AUS81251.1|6596700_6597486_+|TIGR03084-family-protein
MIGLADAIADLTAEAEEVDRLVADLEPPRWALDTPAPGWTIADQVAHLTFIFRLAETAAAEPEAFRAMVSGAEADFEGAVNAALPAFLGPPAEMLRHWRTQRDRTITALAAVPADSVVPWLVRPIPPSVLACAGLMELFGHGQDIADALGVRREATDRLRGLVGFAVLTRDFGYQARGIAPPTEPFRFEISGPSGDLWAFGPEDAGERVTGPARDFCLLVTRRRHHADLAVRASGAEARRWVEIAQAYRGPAGPGRRPGQF
>CP025990.1|AUS81252.1|6597609_6597831_+|hypothetical-protein
MAHARATGVLAVVAFDAGRSRWSPPSREARGSMVTAQRVPLLLGGRGLTLGRLGSRSRRGEGLASLVGYPRGW
>CP025990.1|AUS82055.1|6597982_6598459_-|flavin-reductase
MSWFATGVVVLTVTGERVHGMTANAVSSVSLRPPLVLCCVGRSATMHDAITAASGFAVSVLAADQEDTARYFADRNRPRGAAQFDTVACEPGPRTGAPLLAGALAWLECELTTSVTAGDHTVFLGEVVTARRGRGDRALTFFGGGYRALPAGDTRAGD
>CP025990.1|AUS81253.1|6598554_6599031_-|4-hydroxybenzoyl-CoA-thioesterase
MTGYYEIRHVVGFEETNLVGNVYYVNYLRWQGRCREMFLRERAPGVLDELSQDLKLFTLTVDCEFFSEITAFSELSIRMRLEELTQTQIQFTFDYVLVDPAGEVLVARGRQRIACMRGPNSATAPARVPEELRRALAPYSYGGGGSSPTIPEPRRGTP
>CP025990.1|AUS81254.1|6605520_6606492_+|DUF1702-domain-containing-protein
MPTFLGSLRRLVLAPSLADVSFDGRGFPGPRTPDTPALEAIPQAVVCGFEWGIDARGVGEVERRLRLVEPAMRGFAVEGATMAFTVLDAMSGGVRTRDLLRGEGAPHLFLAYIGIGFAMARLPRVLWRRVLPDLAGTSPYHPTMSWLAVDGYGFDLAYFRTRHWVGGQRVPAAYAWQGDSGYFPRAADQGVGRALWFVHGARVDDVADAVERFPERRRGDLWSGVGLAAAFAGGGTAEATSALRRRAGAYRAELGLGAVFAASARNLADHVPEHTARVVEGLAGLTVPEAVRLAESTATHTSDGDVPPYEVWRGRIRHALGGS

Crispr_ID: CP025990_47

• CRISPR_ID: CP025990_47
• CRISPR_location: 6790061-6792079
• CRISPR_type: Orphan
• Repeat_type: NA:I-C,III-B
• Spacer_info: 27 spacers

Consensus repeat of CP025990_47

Consensus_repeat	Method
NGTTGCGATCCTCACCGGCCCNGGAGGGCCGGTGCAAC	CRT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGT-------GCAAC	PILER-CR
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CRISPRCasFinder

spacers of CP025990_47

>47.1|6790098|36|CP025990|CRT
GGCGCTAGGTGTCCCAGAGGACGCACCGGTTCAGGC
>47.2|6790171|36|CP025990|CRT,PILER-CR,CRISPRCasFinder
CACCTCAGACGTCGTGATGATCGGCTTCGCAGGGTC
>47.3|6790244|38|CP025990|CRT,PILER-CR,CRISPRCasFinder
TCGCGGCTGGCGTCGTGCGCCGCCCGGTAGCGGGCGGC
>47.4|6790319|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
GAGCTCTCTCTCAACGGGTGGCATGTCGCCACCTTAG
>47.5|6790393|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
TCTGGCGGGAGATCTCCGCCCCGCCCTCGGTAGACGA
>47.6|6790467|39|CP025990|CRT,PILER-CR,CRISPRCasFinder
TGCCGGGATGGGCGCCGGGGCGACGATCGAGCTCGGGGT
>47.7|6790543|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
CTCCGTACGATCCACCGGGCGACATCCCTGACGA
>47.8|6790614|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
>47.9|6790685|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
>47.10|6790759|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
>47.11|6790830|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
>47.12|6790904|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
>47.13|6790975|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
>47.14|6791049|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
CCGCGAGCTGGTCTCGCCCCCACCGGTCGGTGCGGTC
>47.15|6791123|36|CP025990|CRT,PILER-CR,CRISPRCasFinder
CACGTACTTCGTGCCGTACGAGTTCGGGTTCGCGGC
>47.16|6791196|37|CP025990|CRT,PILER-CR,CRISPRCasFinder
GACACGCTGCCCGCGCCACCCGGCGCGGGACCACCGC
>47.17|6791270|39|CP025990|CRT,PILER-CR,CRISPRCasFinder
CACCTTGACTTTAGAGGCGACGTCTCCCGTGAGTCCGGC
>47.18|6791346|36|CP025990|CRT,PILER-CR,CRISPRCasFinder
GAGTGAGCCGGGTTCGTGCCGGACCCCATGTGGGAG
>47.19|6791419|38|CP025990|CRT,PILER-CR,CRISPRCasFinder
GCCTTGGGCAGGGGGCACGTTCCCGACGGGACACACAG
>47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder
CCGAGCTCAGCGCCCGCACGCGCCGATAACCAGG
>47.21|6791565|41|CP025990|CRT,PILER-CR,CRISPRCasFinder
TCGTCCCGGAACTGGGTCTGGTTGATCCCAATTGCGCGGAC
>47.22|6791643|38|CP025990|CRT,PILER-CR,CRISPRCasFinder
TGCGCGTGACGGACATCGCCGGCGGCCTCCTGGAGCTG
>47.23|6791718|35|CP025990|CRT,PILER-CR,CRISPRCasFinder
GGGTCCAGCGTCGCCATCGCGAGACGCGGCGTCGG
>47.24|6791790|35|CP025990|CRT,PILER-CR,CRISPRCasFinder
CCCCGCCTGATCGGAGACGGCCAGGGCGACGGGAT
>47.25|6791862|35|CP025990|CRT,PILER-CR,CRISPRCasFinder
CGGTGCGGATGTCATCCCCCTGCGGCGGCCCGCGT
>47.26|6791934|36|CP025990|CRT,PILER-CR,CRISPRCasFinder
CCTACATCGTCTCGATGGTGTCGGCCCTCGCGGCCG
>47.27|6792007|36|CP025990|CRT,PILER-CR,CRISPRCasFinder
TGGGTCGCCGGCGCCGCCTGCCGGGACACCGACCCC

CRISPR arrays and Neighbor proteins around CP025990_47

CRISPR arrays

The CRISPR arrays of CP025990_47

>merge|CP025990|47|6790061-6792079|CRT,PILER-CR,CRISPRCasFinder
TCTACAGATCCTCACCGCCCCGGAGGGCCGGTGCAACGGCGCTAGGTGTCCCAGAGGACGCACCGGTTCAGGCGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACCACCTCAGACGTCGTGATGATCGGCTTCGCAGGGTCGTTGCGATCCTCACCGGCCCCAGAGGGCCGGTGCAACTCGCGGCTGGCGTCGTGCGCCGCCCGGTAGCGGGCGGCGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACGAGCTCTCTCTCAACGGGTGGCATGTCGCCACCTTAGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACTCTGGCGGGAGATCTCCGCCCCGCCCTCGGTAGACGAGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACTGCCGGGATGGGCGCCGGGGCGACGATCGAGCTCGGGGTGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACCTCCGTACGATCCACCGGGCGACATCCCTGACGAGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACAATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACCTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACAATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACCTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACAATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACCTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACCCGCGAGCTGGTCTCGCCCCCACCGGTCGGTGCGGTCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACCACGTACTTCGTGCCGTACGAGTTCGGGTTCGCGGCGTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAACGACACGCTGCCCGCGCCACCCGGCGCGGGACCACCGCGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACCACCTTGACTTTAGAGGCGACGTCTCCCGTGAGTCCGGCGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACGAGTGAGCCGGGTTCGTGCCGGACCCCATGTGGGAGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACGCCTTGGGCAGGGGGCACGTTCCCGACGGGACACACAGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACCCGAGCTCAGCGCCCGCACGCGCCGATAACCAGGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACTCGTCCCGGAACTGGGTCTGGTTGATCCCAATTGCGCGGACGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACTGCGCGTGACGGACATCGCCGGCGGCCTCCTGGAGCTGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACGGGTCCAGCGTCGCCATCGCGAGACGCGGCGTCGGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACCCCCGCCTGATCGGAGACGGCCAGGGCGACGGGATGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACCGGTGCGGATGTCATCCCCCTGCGGCGGCCCGCGTGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACCCTACATCGTCTCGATGGTGTCGGCCCTCGCGGCCGGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAACTGGGTCGCCGGCGCCGCCTGCCGGGACACCGACCCCGTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC

>CP025990|47|37|6790061-6792079|CRT
TCTACAGATCCTCACCGCCCCGGAGGGCCGGTGCAAC	GGCGCTAGGTGTCCCAGAGGACGCACCGGTTCAGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CACCTCAGACGTCGTGATGATCGGCTTCGCAGGGTC
GTTGCGATCCTCACCGGCCCCAGAGGGCCGGTGCAAC	TCGCGGCTGGCGTCGTGCGCCGCCCGGTAGCGGGCGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GAGCTCTCTCTCAACGGGTGGCATGTCGCCACCTTAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TCTGGCGGGAGATCTCCGCCCCGCCCTCGGTAGACGA
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGCCGGGATGGGCGCCGGGGCGACGATCGAGCTCGGGGT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTCCGTACGATCCACCGGGCGACATCCCTGACGA
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CCGCGAGCTGGTCTCGCCCCCACCGGTCGGTGCGGTC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CACGTACTTCGTGCCGTACGAGTTCGGGTTCGCGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	GACACGCTGCCCGCGCCACCCGGCGCGGGACCACCGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CACCTTGACTTTAGAGGCGACGTCTCCCGTGAGTCCGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GAGTGAGCCGGGTTCGTGCCGGACCCCATGTGGGAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GCCTTGGGCAGGGGGCACGTTCCCGACGGGACACACAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCGAGCTCAGCGCCCGCACGCGCCGATAACCAGG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TCGTCCCGGAACTGGGTCTGGTTGATCCCAATTGCGCGGAC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGCGCGTGACGGACATCGCCGGCGGCCTCCTGGAGCTG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GGGTCCAGCGTCGCCATCGCGAGACGCGGCGTCGG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCCCGCCTGATCGGAGACGGCCAGGGCGACGGGAT
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CGGTGCGGATGTCATCCCCCTGCGGCGGCCCGCGT
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCTACATCGTCTCGATGGTGTCGGCCCTCGCGGCCG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGGGTCGCCGGCGCCGCCTGCCGGGACACCGACCCC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC

>CP025990|47|40|6790134-6792079|PILER-CR
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CACCTCAGACGTCGTGATGATCGGCTTCGCAGGGTC
GTTGCGATCCTCACCGGCCCCAGAGGGCCGGTGCAAC	TCGCGGCTGGCGTCGTGCGCCGCCCGGTAGCGGGCGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GAGCTCTCTCTCAACGGGTGGCATGTCGCCACCTTAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TCTGGCGGGAGATCTCCGCCCCGCCCTCGGTAGACGA
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGCCGGGATGGGCGCCGGGGCGACGATCGAGCTCGGGGT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTCCGTACGATCCACCGGGCGACATCCCTGACGA
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CCGCGAGCTGGTCTCGCCCCCACCGGTCGGTGCGGTC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CACGTACTTCGTGCCGTACGAGTTCGGGTTCGCGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	GACACGCTGCCCGCGCCACCCGGCGCGGGACCACCGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CACCTTGACTTTAGAGGCGACGTCTCCCGTGAGTCCGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GAGTGAGCCGGGTTCGTGCCGGACCCCATGTGGGAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GCCTTGGGCAGGGGGCACGTTCCCGACGGGACACACAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCGAGCTCAGCGCCCGCACGCGCCGATAACCAGG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TCGTCCCGGAACTGGGTCTGGTTGATCCCAATTGCGCGGAC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGCGCGTGACGGACATCGCCGGCGGCCTCCTGGAGCTG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GGGTCCAGCGTCGCCATCGCGAGACGCGGCGTCGG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCCCGCCTGATCGGAGACGGCCAGGGCGACGGGAT
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CGGTGCGGATGTCATCCCCCTGCGGCGGCCCGCGT
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCTACATCGTCTCGATGGTGTCGGCCCTCGCGGCCG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGGGTCGCCGGCGCCGCCTGCCGGGACACCGACCCC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC

>CP025990|47|45|6790134-6792079|CRISPRCasFinder
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CACCTCAGACGTCGTGATGATCGGCTTCGCAGGGTC
GTTGCGATCCTCACCGGCCCCAGAGGGCCGGTGCAAC	TCGCGGCTGGCGTCGTGCGCCGCCCGGTAGCGGGCGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GAGCTCTCTCTCAACGGGTGGCATGTCGCCACCTTAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TCTGGCGGGAGATCTCCGCCCCGCCCTCGGTAGACGA
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGCCGGGATGGGCGCCGGGGCGACGATCGAGCTCGGGGT
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTCCGTACGATCCACCGGGCGACATCCCTGACGA
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	AATTCGCTTTCGCGCTATTAGCGGGGTGTCTTCC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CTGCGATCCCATCGTGGTCGGCGTGTACGAGGACGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CCGCGAGCTGGTCTCGCCCCCACCGGTCGGTGCGGTC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	CACGTACTTCGTGCCGTACGAGTTCGGGTTCGCGGC
GTTGCGATCCTCACCGGCCCCGGAGGGCCGGTGCAAC	GACACGCTGCCCGCGCCACCCGGCGCGGGACCACCGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CACCTTGACTTTAGAGGCGACGTCTCCCGTGAGTCCGGC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GAGTGAGCCGGGTTCGTGCCGGACCCCATGTGGGAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GCCTTGGGCAGGGGGCACGTTCCCGACGGGACACACAG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCGAGCTCAGCGCCCGCACGCGCCGATAACCAGG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TCGTCCCGGAACTGGGTCTGGTTGATCCCAATTGCGCGGAC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGCGCGTGACGGACATCGCCGGCGGCCTCCTGGAGCTG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	GGGTCCAGCGTCGCCATCGCGAGACGCGGCGTCGG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCCCGCCTGATCGGAGACGGCCAGGGCGACGGGAT
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CGGTGCGGATGTCATCCCCCTGCGGCGGCCCGCGT
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	CCTACATCGTCTCGATGGTGTCGGCCCTCGCGGCCG
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC	TGGGTCGCCGGCGCCGCCTGCCGGGACACCGACCCC
GTTGCGATCCTCACCGGCCCTGGAGGGCCGGTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS81336.1|6789533_6789983_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81346.1|6808765_6809623_+|DUF4291-domain-containing-protein	unknown	unknown	gnl|CDD|379483
CP025990.1|AUS81341.1|6798024_6798855_+|oxidoreductase	unknown	unknown	gnl|CDD|381357
CP025990.1|AUS81337.1|6792576_6793506_-|proline-dehydrogenase	unknown	unknown	gnl|CDD|223580
CP025990.1|AUS81329.1|6781503_6782838_-|MFS-transporter	unknown	unknown	gnl|CDD|340877
CP025990.1|AUS81330.1|6782915_6784250_-|amino-acid-deaminase	unknown	unknown	gnl|CDD|143492
CP025990.1|AUS81335.1|6788421_6788835_+|RidA-family-protein	unknown	unknown	gnl|CDD|100004
CP025990.1|AUS81339.1|6795284_6796916_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
CP025990.1|AUS81344.1|6805636_6806581_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81343.1|6801339_6805083_+|hypothetical-protein	unknown	unknown	gnl|CDD|236657
CP025990.1|AUS81340.1|6797281_6797653_-|thioredoxin	unknown	unknown	gnl|CDD|239245
CP025990.1|AUS81334.1|6787631_6788405_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
CP025990.1|AUS81345.1|6807363_6808803_+|alkaline-phosphatase	unknown	unknown	gnl|CDD|293736
CP025990.1|AUS81338.1|6793531_6795157_-|1-pyrroline-5-carboxylate-dehydrogenase	unknown	unknown	gnl|CDD|143441
CP025990.1|AUS81328.1|6780269_6781220_+|hydrolase	unknown	unknown	gnl|CDD|185683
CP025990.1|AUS81332.1|6785499_6786222_-|2-dehydro-3-deoxyphosphogluconate-aldolase	unknown	unknown	gnl|CDD|188632
CP025990.1|AUS81331.1|6784246_6785398_-|acetylornithine-deacetylase	unknown	unknown	gnl|CDD|349889
CP025990.1|AUS82063.1|6778172_6779138_+|arsenite-transporter	unknown	unknown	gnl|CDD|223869
CP025990.1|AUS81342.1|6799141_6800140_-|pirin	unknown	unknown	gnl|CDD|224655
CP025990.1|AUS81333.1|6786532_6787570_+|sugar-kinase	unknown	unknown	gnl|CDD|238571

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS81346.1|6808765_6809623_+|DUF4291-domain-containing-protein	gnl|CDD|379483	pfam14124, DUF4291, Domain of unknown function (DUF4291). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 190 and 214 amino acids in length. There are two conserved sequence motifs: VYQAY and RMTW.	1.09607e-103
CP025990.1|AUS81341.1|6798024_6798855_+|oxidoreductase	gnl|CDD|381357	cd19131, AKR_AKR5C2, Escherichia coli 2,5-diketo-D-gluconic acid reductase A (DkgA/YqhE) and similar proteins. Escherichia coli DkgA/YqhE is a founding member of aldo-keto reductase family 5 member C2 (AKR5C2). DkgA/YqhE (EC 1.1.1.274), also called 2,5-DKG reductase A, or 2,5-DKGR A, or 25DKGR-A, or AKR5C, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives.	7.65958e-162
CP025990.1|AUS81337.1|6792576_6793506_-|proline-dehydrogenase	gnl|CDD|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	9.60401e-64
CP025990.1|AUS81329.1|6781503_6782838_-|MFS-transporter	gnl|CDD|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.4463e-78
CP025990.1|AUS81330.1|6782915_6784250_-|amino-acid-deaminase	gnl|CDD|143492	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase. This subfamily is composed of Burkholderia cepacia cryptic D-serine dehydratase (cryptic DSD), which is also called D-serine deaminase, and similar bacterial proteins. Members of this subfamily are fold type III PLP-dependent enzymes with similarity to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as dimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on similarity, it is possible cryptic DSDs may also form dimers. Cryptic DSDs are distinct from the ubiquitous bacterial DSDs coded by the dsdA gene, mammalian L-serine dehydratases (LSD) and mammalian serine racemase (SerRac), which are fold type II PLP-dependent enzymes. At present, the enzymatic and biochemical properties of cryptic DSDs are still poorly understood. Typically, DSDs catalyze the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia.	1.3232e-127
CP025990.1|AUS81335.1|6788421_6788835_+|RidA-family-protein	gnl|CDD|100004	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	4.53745e-33
CP025990.1|AUS81339.1|6795284_6796916_+|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	8.48355e-17
CP025990.1|AUS81345.1|6807363_6808803_+|alkaline-phosphatase	gnl|CDD|293736	cd16012, ALP, Alkaline Phosphatase. Alkaline phosphatases are non-specific membrane-bound phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH. Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymatic activity. Mammalian alkaline phosphatase is divided into four isozymes depending upon the site of tissue expression. They are Intestinal ALP, Placental ALP, Germ cell ALP and tissue nonspecific alkaline phosphatase or liver/bone/kidney (L/B/K) ALP.	2.24214e-88
CP025990.1|AUS81343.1|6801339_6805083_+|hypothetical-protein	gnl|CDD|236657	PRK10150, PRK10150, beta-D-glucuronidase; Provisional.	3.76903e-39
CP025990.1|AUS81340.1|6797281_6797653_-|thioredoxin	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.34606e-35
CP025990.1|AUS81334.1|6787631_6788405_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	7.10269e-72
CP025990.1|AUS81338.1|6793531_6795157_-|1-pyrroline-5-carboxylate-dehydrogenase	gnl|CDD|143441	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), families 4 and 17: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), also known as ALDH4A1 in humans, is a mitochondrial homodimer involved in proline degradation and catalyzes the NAD + -dependent conversion of P5C to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Also included in this CD is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences.	0
CP025990.1|AUS81328.1|6780269_6781220_+|hydrolase	gnl|CDD|185683	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.	3.75494e-27
CP025990.1|AUS81332.1|6785499_6786222_-|2-dehydro-3-deoxyphosphogluconate-aldolase	gnl|CDD|188632	cd00452, KDPG_aldolase, KDPG and KHG aldolase. KDPG and KHG aldolase. This family belongs to the class I adolases whose reaction mechanism involves Schiff base formation between a substrate carbonyl and lysine residue in the active site. 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase, is best known for its role in the Entner-Doudoroff pathway of bacteria, where it catalyzes the reversible cleavage of KDPG to pyruvate and glyceraldehyde-3-phosphate. 2-keto-4-hydroxyglutarate (KHG) aldolase, which has enzymatic specificity toward glyoxylate, forming KHG in the presence of pyruvate, and is capable of regulating glyoxylate levels in the glyoxylate bypass, an alternate pathway when bacteria are grown on acetate carbon sources.	4.03332e-54
CP025990.1|AUS81331.1|6784246_6785398_-|acetylornithine-deacetylase	gnl|CDD|349889	cd03894, M20_ArgE, M20 Peptidase acetylornithine deacetylase. Peptidase M20 family, acetylornithine deacetylase (ArgE, Acetylornithinase, AO, N2-acetyl-L-ornithine amidohydrolase, EC 3.5.1.16) subfamily. ArgE catalyzes the conversion of N-acetylornithine to ornithine, which can then be incorporated into the urea cycle for the final stage of arginine synthesis. The substrate specificity of ArgE is quite broad; several alpha-N-acyl-L-amino acids can be hydrolyzed, including alpha-N-acetylmethionine and alpha-N-formylmethionine. ArgE shares significant sequence homology and biochemical features, and possibly a common origin, with glutamate carboxypeptidase (CPG2) and succinyl-diaminopimelate desuccinylase (DapE), and aminoacylase I (ACY1), having all metal ligand binding residues conserved.	8.59777e-101
CP025990.1|AUS82063.1|6778172_6779138_+|arsenite-transporter	gnl|CDD|223869	COG0798, ACR3, Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism].	1.43935e-50
CP025990.1|AUS81342.1|6799141_6800140_-|pirin	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	4.91083e-67
CP025990.1|AUS81333.1|6786532_6787570_+|sugar-kinase	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	4.05612e-83

Protein sequences

>CP025990.1|AUS81336.1|6789533_6789983_+|hypothetical-protein
MGASRRCGRVLVGPLLAALVTISGCVRESAGHATLTTNGDQSGTSETDASATGGASTPSSGTGSSSASATLGGLDPCELLDDELTSVGIDPATGERNSIGINHARAYGQLDPSAPRVLLQLNTFLEVDEQNHGDEEVEEIEADGAARCD
>CP025990.1|AUS81335.1|6788421_6788835_+|RidA-family-protein
MAAQSKTAIRTDAAPAPAHTFSQGVRKGPLLQVSGQGPVDPTSNEYVFQGDVHAQTIRTLENVAAILAAGGASFEDVIMLRVYLTTRDDFATMNEAYGEFVTARVPSGVLPARTTVFTGLPREEMLVEIDALAVVND
>CP025990.1|AUS81334.1|6787631_6788405_+|IclR-family-transcriptional-regulator
MSQSLARALSILIDLGEREQSLDDLAERLGVHKTTVLRLLRTLESERFVFRDDAHRYHLGSRLFALSSLALEQREVRNIASPHLAELNQRTGQTVHLAVYEAGEVIYVDKYDSRHPVRMYSRIGLRAPLNCAAVSKVLLADMPPAKRRGVVDGIDFVRFTDQTITDAPTLLAELDRVANQGYAVDQAEHESFINCVGAPVRDASGRVAAAVSVSVPTVVLSYEQVLELLPDLLSTAAAISRDCGYGGTAPPRSTSAR
>CP025990.1|AUS81333.1|6786532_6787570_+|sugar-kinase
MPLPAQRPPRAVCVGESMVVLVPHRTGPLEHAEEFRRYAGGAESNVAGALAGLGVDTSWVSRLGDDGFGRYLRADIADRGVDVSAVEIDPLRPTGLYVKETGDGTGDLPAGRSRMHYYRAASAASAMSPDLVSGGPARDLLDRADLVHVTGITAGISDSATDLLWHLLSRPRPSTTVSFDLNWRPGLWHGRDPAVLGRLCALADVVLLGADEAAEVLGSSSPARLRELLPNPDMLVVKNDAHDAIAVDRTGAEVVVPALDVEVVEPVGAGDAFAAGYLAGTLRDLPVAHRLRLGHLCAARALAVPGDHGVPPSPATITALLARADDEWARTRVSRLGVDTPPVAS
>CP025990.1|AUS81332.1|6785499_6786222_-|2-dehydro-3-deoxyphosphogluconate-aldolase
MTAREPRVSPGSSPPEAHPAVEALATDRALVVVRASTLPDAAELTAALTAGGLRIVEFTFTTPDLPRHLRRASDTSAETGAIVGAGTVRTADQARAAADAGARFLVTPGLQPEVAEAAHDLGLPVLLGALTPSEVLTAQDLGAAAVKVFPANRLGPRYLRDLAGPLPTTPLVPSGGVTARDAAAYLAAGAFAVAAGTDVAPAEAIAAGDWPALTRRAAEFVRALRARPATPDHPTPEAVA
>CP025990.1|AUS81331.1|6784246_6785398_-|acetylornithine-deacetylase
MTDVVDLVSQLIRIPSVNPRGRAEPAETPLAEFVADWARRHGMTADLHEVLDGRYNVVVTVPGDSADTILLETHLDTVETEGMTVPPFEPTIRDGLLYGRGSCDAKGPLAVFLTAMAELAAGGPRPHTVTLAGVVDEEHIYRGVLALRDQGINPVGAVIGEPTSLRMVTAHKGCMRCRITARGPGGHSSEPWGKTNPITTAARIVDYLADEYAPALDAKARPLVGPPSLAVTMIDGGSGPNVLPESTTLTIDRRTVAGEDPHQVWGELRDELLRRWPEGVDVAEPHIVDYALETDPEDPFVRSVASVLAGAGHNPEAKGVGHGTDASKIALDGVPCVVFGPGAIAQAHTPAEFVPLDELHAARKVVGELLRSPVLDTKGAQAR
>CP025990.1|AUS81330.1|6782915_6784250_-|amino-acid-deaminase
MTDNTGTTRTPTTPARPDPGFIDDGAIGWRFKGLPPAAAHQTLAQLGDSGRRIFDGDFGFPLLVLRDSALRHNAELMALFAADRGMSLAPHLKTSASPQVADYALRAGAWGVTVANPFQARVFMAAGHDRILLANQLVDRAFAVEAAQWLGEDPERRFSCYVDSPAGVAVLADALADQDPNRPLPVLVEVGHEGGRGGCRDTAALAATIDAVRANPTLALAGVSGYEGSVSHSRGSEGLRAVRDYLSWVRAAMDTVLAHRDPRLPEYVVSAGGSLYFDLVGEELATGWPADVPVRVIARPGAYLTHDQGLYHALSPLDGSGSDPAEVARLAPAIEVWAPVLTRPTPDQVILGAGRRELNYDEGLPLPIEARDHRGGSPRPTTGWQVTALNDQHAFLTVPPDADLGPSDLVRLGISHPCTAHDRWLSAVIAADDDTVVSVARCYF
>CP025990.1|AUS81329.1|6781503_6782838_-|MFS-transporter
MTAPTSTEASTEKRSRTRFAILASNFMILMLNYADRAVIGVAAPLIITEFGFSNAAFGWILAAFAFTYSPFGFIGGWLADKFGPAKVMGWAAIAWSVFTALTAAGVGFVSLLIIRLLFGAGEGPQATVTAKVMHNWFPKKKLGTAVGIANAATPLGGAIGTPVVVAIMDATQGNWRLPFIIFGVLGVLFAIGWFVVVRDTPEQHPWVSKGELAHIRQDAAPAAEDDADADANAEPWWRYLTLPAVWTTAVAFFGYAWILWTFLNWFPTYLVNERGIDLSDLAVTGAIPWVGGCIGLALGGAFTDWLVRRTGKSVAPRRWTVVICLAATGLLFGSIGTVSGTGSAVALMTVVVFLLYFTGAQYWLIVGEAVPGSRYGSVSGAMQMFATTASIIAPMITGYLVDSSLGWTGTFTVAAVVALTGALLLAFFGRVRTPDTRQAGQPAS
>CP025990.1|AUS81328.1|6780269_6781220_+|hydrolase
MPLGTGRSARRRHLPALVALAGAVALPVGLLPALGGTATAGAEAAEAPTQVLFDDFDYTSHTDPRLRERGWSVRNYPGGPGIGGDTWSAANISFRSEGAGAVLRLEATTDGTVAGTSQAQINTQRRFHHGTYAARVRFTDTPVSGPDGDQVLQTFYTITPLRWDYDPEYGELDFEYLPNGGWGQPSSALFLTSWDTYRPDPWDARNESTVRPGSLEGWHDLVVQADGGTRTIRYYLDGQLVAEHGGPNYPASRMSIDFNQWFIPEGFVGSSASRTYEQEVDWVYHAKDEILSPAEVAAQVAAQRAAGIPHLDTITE
>CP025990.1|AUS82063.1|6778172_6779138_+|arsenite-transporter
MSRWERLQSVLVAAAAGGGLAVGVAWPVGAVLEHLVLPALLLMLVCVFARLDAAQVGAFRRAGAVVTTSLVLNFVWTPLLAWALGSGLLGDAPDLRIGLLLLLVTPCTDWYLVFTSLARGHLGLAAALLPVNLVLQLVLLPVYVVLLGGPAAMVDAGTLVEAVLVVLVVPLALGLGLRWGTGRWRGPAWRDRVLDGPAGALVLPLLCVAVFAMFAWQARTVVEHGSALLALLIPLLVFFVVTPLLAVGTGRALRLPADQRVTLTMTTTARNSPIALAVAVAAFPDRPLIAVALVVGPLLELPVLALLSQVVRVREPAGSTG
>CP025990.1|AUS81337.1|6792576_6793506_-|proline-dehydrogenase
MLRSILLAAGRSPLARTVVERTPATRYVVRRFVAGDTLDDAITATTALADDGLRITLDHLGEDTTDREQADATVDAYVRLLDRLRTANLAQAAEVSLKLSAVGQFLGSDGQRIALDNARRVCEAAAAAGTTVTLDMEDHTTTDSTLEVLRELRTDWPWVGAVLQAYLRRTEADCRDLAGPGSRVRLCKGAYKEPSSVAFQSRHEVDRAYVRCLDVLMSGEGYPMVATHDPRLVAITARLAGDNNRARDSYEYQMLYGIRPEEQLRLAGEGNTMRVYLPYGDEWYGYFMRRLAERPANVGFFLRALATKS
>CP025990.1|AUS81338.1|6793531_6795157_-|1-pyrroline-5-carboxylate-dehydrogenase
MDAVTNVPTPQNEPVLSYAPGTPERAELQAKLTELAAEPRELTLTIGGEQRMGGGRRIDVVQPHNHRHVLGTLGNATQQDATDAVEAARQAAPGWRALSYDDRAAVLLRAADLLSGPWRSTLNAATMLGQSKTAIQAEIDSACELADFWRFNVQYGRDILTEQPRSSAGVWNRMDHRPLEGFVYAITPFNFTAIAGNLPTAPALMGNTVVWKPAPTQSFAAHLTMRLLEAAGLPPGVINLVTGDGLDVSEVALAQPDLAGIHFTGSTATFQHLWGAVGANIANYRGYPRIVGETGGKDFVLAHPSADVDTLRTALVRGAFEFQGQKCSAASRAYIPRSLWTRLRDDLVAEVEGLTMGDVTDLSNFMGAVIDDRSFAKLSRVLDMARTDPTLEVIAGGTADDSEGYFVRPTVLVGTDPEHEVFRDEYFGPVLAVHVYDDADFEKVVRQMESVSPYALTGAVIAQDRSAIAYASEQLRFAAGNFYVNDKPTGAVVGQQPFGGARASGTNDKAGSVLNLLRWTSPRSLKETLVPPTSSGYPHQG
>CP025990.1|AUS81339.1|6795284_6796916_+|PucR-family-transcriptional-regulator
MTVRGVSAAGAPGASLRQLLLALDDPLVELVAAPAGLDVVIGEVVILDPEDAPDTQRGDLILLIGARDASALPAVRAAARRGAAAVAVKVTSSGASDALRAAAVDAGVALLAVRPAARWEQVESLASGVVSRARVSADADEGEVLGDLFSTAQTVAHLTGGIVSIEDTAARVLAYSRSSGEVDELRRLSILGRQGPEPYLEMLREWGVYQRLRSGEDVVRIDERPDLGIRRRIAVGVHAGGRPLGAIWVQEGDEPLTEHAERSLLGAARVTALQLVRHRNEPSAGLRLRENLLAGLLNGRLDPSAAAGQLGVDSRRPAAVVAFASRVESPGAVVDRPELELRRDQLGNVISMHAAAFRRGALVSQLGTRTYALLPELSGSGEAAVVGLAREIISASRGIGLVVRAAVGSVVPELGGAADSRRQADRVLDAMAGDTAARVATIADWRAEVLVSETVDLLAEHPAIRDPRVTALRRHDERNNGSLVGSVVAYLESFGDVRAAARRLHVHPNTLRYRIRRAEEVSGLDLGDARQRLFTELQLRLRE
>CP025990.1|AUS81340.1|6797281_6797653_-|thioredoxin
MSNTVELTKENFNEVVSENDFVLVDFWASWCGPCRQFAPVYDRVADKNPDLVFGKVDTEAQQELAGAFEIRSIPTLAIIRDNVLVFSQPGALPEAALEDVIRQARELDMDEVRRSVAESSKAE
>CP025990.1|AUS81341.1|6798024_6798855_+|oxidoreductase
MTTVPTLTLNNGVAMPQLGFGVYQVPDEEATATVRAALDAGYRSIDTAALYQNEIGTGRALAESGIPREELFVTTKLWNTDQGYDTTLRAFDASLERLGLDQVDLYLIHWPAPKLDRYVDTWRAFERIYSEDRTRAIGVSNFQPAHLARLFEASGIVPAVNQVELHPRLQQLAVREFDASNGIATEAWGPLGQGKGGLLDDPTLTQLAAKHGRTPAQIVLRWHIQLGNVVIPKSSTPSRMRENIDVFDFQLDADDMDSIAGMETGARGGPDPDVLS
>CP025990.1|AUS81342.1|6799141_6800140_-|pirin
MPAVTVENTLELPRLAEAAPEGRQRPVRSVTTAPSGHEGEGFPVYRAFAGVSAGLLDPFIHLDQMGEVEYAPGEPKGTPWHPHRGFETVTYMMDGQMEHSDSHGGGGVIADGATQWMTAGSGILHIEKPPEHLVMSGGLFHGIQLWVNLPRANKWNPPQYQSIQGGETTLLSSPDGGALVRVIAGEVDGHHGPGNTFTPITLLHATLSPGARLVLPWRTDFNALVYALSGRGGVGEERHPLRAAQLAVFGAGDLLTIEATDHPDARTPDLDVLVLGGQPIREPVVQYGPFVMNSKAEVIQAFEDFQAGRMGVIPTERVPHAGHDQAPPAREN
>CP025990.1|AUS81343.1|6801339_6805083_+|hypothetical-protein
MLASPARPPPPSPPTRSRDTRASDHPDAQGLNERQRPGEVPVMHWSRQGADTPARPHPPRRRPTAILAAVVIMGGMAPLSTPGSADAEPATTTVNGQVVDADTGRPLPGAVVHVTEQTSTVRTDADGRFTVPEAPVDALALVAARQGYSFGWHPLEDPNAPVTLALEAETPDTVPHPDYPRPDFDRRAGVNGQWASLNGTWSLDFDPSDVGVDEGWHEGDHEWAHAVRVPFAYNSLAGIGEERRAGNQVYASQFAEARGTVWYQRDLTVPEDWPTDRGTLLRFGAVEWRAEVFLDGNRVGENDGGYSPFDVDLGPLRPGAEHSLVVRVEVPDNSATTPYPQGKQMGWYTDTGGIWQSVWIEPADSARLTTVHTTPEIDFDGREATAARVTVDVEARGAPDGTVELAVRAQDGEPGARAGQRQDGVSAPGLPVPVEPTVGEVVATATVTLVDGAGSAVIDVPDPRLWEPEAPWLYRVDASLTDQAGSDRVDTWFGLRTVSREWLPGHSPEEQDDPAEQYQYLFLNNRPVYLRSVLDQNFNPWGNYSYTGLYQGADLRGGELEDPGKGSVLFDLALTKQLGFNSVRPHIKVNDPLYYHWADVLGLLVWYDQPNFGYDGYGPEAERLWEEVLRDAVHRDYNHPSIVIWDAFNEAWGFNATPGGPIRDDAKPWIERMFDLTTDLVRGTRLVVDNSPCCENGHLVTDINDFHGYYSTWEEWAATVDRIVSNTYPGSTHNFEDGRTQSGQPLMNSEFGPWSGGREKDQEVATPFRYTAELFRAEQKMSGYLFTELTDLEWEWNGWAAYDRTLQVPGYLDADGAQGGVGLANADDVLLVGERPVQRLVGDDPIGLTVRSSLFSGRDLGETTLRWRVTGTDGTGAELPSSDWAEVPVSPETFAVTELTTVEVRPPDGFVAGRLDAELLSDGQPVASGQTVLAAWGAAAEQAAGTLALDPAGADVEWPQGSEVFSQDGASAVVGWGDGEFRWHLTVPEDLRDGGFDSAQLVLEAAASRPSLPRTSFPQTSERVFPTTLSATVSGAGTVVETEAVVLPDDPADARGALSHESGFHPGQYGYRVLLDLDVEDMRAAVADGEVTVTLRGAGGGLTVLGPRTGRFGVPPQLVLSEGAGLPGPAVAGGEPYLRTAEAAGVTTHLLAGDATAGAEAAMTVSVVNDSGEVVRDVRPAFVAPEGWTVEALGDHTVGELAPGEGAHLRYRVVPDGDGPVTVRTRAYYSTGEGRQVTEEPWELDLS
>CP025990.1|AUS81344.1|6805636_6806581_-|hypothetical-protein
MAAKHDNQWPVVVTDSCAGAYARWRGLTDHGAAKATLRRMVDELGEVTDQLPPQLAGRRSRSGFFLLVPDTLVLPLVRDSDGSTRWIATHCVPFPACDPPDLDALVALRGRELLARIHLTRHAVERFQERCGGAPDLDDAARQLRSTIAPTVRARRRPPGWCRTTPAEVFLVAGEHDQYCLPCRPGAVAELDATTCLHRASDLFERTGARLHAVCQVDRTRLPVGGEADRLLSSSVPLGGTLAWARPKWAAPHDGATWWVVFPNRVAAPVRWQPAKPNRPLRVLGVHDGRPWPVRLWSRIRHRLRRRGTGNRPG
>CP025990.1|AUS81345.1|6807363_6808803_+|alkaline-phosphatase
MTEKAGRQRWRRPASVAAASALALTIGAPTAVGLEPGTAEHVAPLGFGPKNVIHLISDGMGYNHVDVASLWEHGTTAHQVRVDPDSGTTEHLPATPAQVYEDWPVQLGMSTYHDGHSYEADRAWAGFDYPSEDFTDSSAAGTALATGVRTYNGAIGLAPDRGPVKNLTERAQELGKASGVVSSVPFSHATPAAYVAHNPDRNDYHGIAKEMLFEHDINVVFGPGHPDFDEDGQRRDEPDHRYVDEWTWGAVQRGATAFDLVETPEEFAALAQSSNPPRHVLGVPQVAATLQYDRGGPDRTPDGRPVPGALPYTAPPVENVPTLADMTTSALAVLENASDEGLFLMIEGGAVDWASHDNDTARVIEEQIDFNRAVEAVVDWVEESSSWHETLVVVTADHETGYLAGPGADPTWTPVIGSAGQLPHVSWHSGNHTNALVPLFAKGPGASRLEQHADNIDPVRGRYLNNTDVAKVVFDFWGR
>CP025990.1|AUS81346.1|6808765_6809623_+|DUF4291-domain-containing-protein
MSPRSSSTSGDAEHSWSTRTDSGPPPLVAAPPREPGPVPGAQPCSSPSVTTRRPGRAPGANLRKSVAPAAGAPDARPVSLREVRANADASSVVVYQAYPAAIADPALRAGTFVAPFKQERMTWIKPSFRWMMYRCGWATKPGQERVLAVRISLEGLWWALRRSCASSHGAGRHPNREAWRRQLAESPVRVQWDPERDMDLNPLPQRSIQIGLGPEASRRYVDEWIVELTDVTELAREVGRLVRAGDQDGARALLPEEHPLTVPADIAERIDVTGPAPARTNGQGR

Crispr_ID: CP025990_48

• CRISPR_ID: CP025990_48
• CRISPR_location: 6810195-6810284
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas8c

Consensus repeat of CP025990_48

Consensus_repeat	Method
GGGAGCATCCCCGCGTACGCGGGGCCGAT	CRISPRCasFinder

spacers of CP025990_48

>48.1|6810224|32|CP025990|CRISPRCasFinder
GCCCTGGCGGTCCTCAAGCTGACCTACGCCAC

CRISPR arrays and Neighbor proteins around CP025990_48

CRISPR arrays

The CRISPR arrays of CP025990_48

>merge|CP025990|48|6810195-6810284|CRISPRCasFinder
GGGAGCATCCCCGCGTACGCGGGGCCGATGCCCTGGCGGTCCTCAAGCTGACCTACGCCACGGGAGTATCCCCGCGTACGCGGGGCCGAT

>CP025990|48|46|6810195-6810284|CRISPRCasFinder
GGGAGCATCCCCGCGTACGCGGGGCCGAT	GCCCTGGCGGTCCTCAAGCTGACCTACGCCAC
GGGAGTATCCCCGCGTACGCGGGGCCGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP025990.1|AUS82065.1|6820583_6821210_-|hypothetical-protein	unknown	unknown	gnl|CDD|369438
CP025990.1|AUS81346.1|6808765_6809623_+|DUF4291-domain-containing-protein	unknown	unknown	gnl|CDD|379483
CP025990.1|AUS81352.1|6821114_6821849_+|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81337.1|6792576_6793506_-|proline-dehydrogenase	unknown	unknown	gnl|CDD|223580
CP025990.1|AUS81339.1|6795284_6796916_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
CP025990.1|AUS81349.1|6812614_6812866_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81342.1|6799141_6800140_-|pirin	unknown	unknown	gnl|CDD|224655
CP025990.1|AUS82064.1|6818616_6819069_+|hypothetical-protein	cas8c	pfam09709_cas8c_CAS-I-C	gnl|CDD|378245
CP025990.1|AUS81347.1|6810695_6811265_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
CP025990.1|AUS81350.1|6813331_6814435_+|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
CP025990.1|AUS81340.1|6797281_6797653_-|thioredoxin	unknown	unknown	gnl|CDD|239245
CP025990.1|AUS81345.1|6807363_6808803_+|alkaline-phosphatase	unknown	unknown	gnl|CDD|293736
CP025990.1|AUS81338.1|6793531_6795157_-|1-pyrroline-5-carboxylate-dehydrogenase	unknown	unknown	gnl|CDD|143441
CP025990.1|AUS81341.1|6798024_6798855_+|oxidoreductase	unknown	unknown	gnl|CDD|381357
CP025990.1|AUS81348.1|6811355_6812309_+|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|235737
CP025990.1|AUS81351.1|6815567_6816773_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
CP025990.1|AUS81344.1|6805636_6806581_-|hypothetical-protein	unknown	unknown	unknown
CP025990.1|AUS81343.1|6801339_6805083_+|hypothetical-protein	unknown	unknown	gnl|CDD|236657

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP025990.1|AUS82064.1|6818616_6819069_+|hypothetical-protein	cas8c	pfam09709_cas8c_CAS-I-C	3.6e-17	56.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP025990.1|AUS82065.1|6820583_6821210_-|hypothetical-protein	gnl|CDD|369438	pfam07591, PT-HINT, Pretoxin HINT domain. A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The domain is predicted to function in releasing the toxin domain by autoproteolysis.	9.92023e-07
CP025990.1|AUS81346.1|6808765_6809623_+|DUF4291-domain-containing-protein	gnl|CDD|379483	pfam14124, DUF4291, Domain of unknown function (DUF4291). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 190 and 214 amino acids in length. There are two conserved sequence motifs: VYQAY and RMTW.	1.09607e-103
CP025990.1|AUS81337.1|6792576_6793506_-|proline-dehydrogenase	gnl|CDD|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	9.60401e-64
CP025990.1|AUS81339.1|6795284_6796916_+|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	8.48355e-17
CP025990.1|AUS81342.1|6799141_6800140_-|pirin	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	4.91083e-67
CP025990.1|AUS82064.1|6818616_6819069_+|hypothetical-protein	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.34112e-15
CP025990.1|AUS81347.1|6810695_6811265_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	8.0496e-11
CP025990.1|AUS81350.1|6813331_6814435_+|LuxR-family-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.49107e-12
CP025990.1|AUS81340.1|6797281_6797653_-|thioredoxin	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.34606e-35
CP025990.1|AUS81338.1|6793531_6795157_-|1-pyrroline-5-carboxylate-dehydrogenase	gnl|CDD|143441	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), families 4 and 17: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), also known as ALDH4A1 in humans, is a mitochondrial homodimer involved in proline degradation and catalyzes the NAD + -dependent conversion of P5C to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Also included in this CD is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences.	0
CP025990.1|AUS81341.1|6798024_6798855_+|oxidoreductase	gnl|CDD|381357	cd19131, AKR_AKR5C2, Escherichia coli 2,5-diketo-D-gluconic acid reductase A (DkgA/YqhE) and similar proteins. Escherichia coli DkgA/YqhE is a founding member of aldo-keto reductase family 5 member C2 (AKR5C2). DkgA/YqhE (EC 1.1.1.274), also called 2,5-DKG reductase A, or 2,5-DKGR A, or 25DKGR-A, or AKR5C, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives.	7.65958e-162
CP025990.1|AUS81348.1|6811355_6812309_+|short-chain-dehydrogenase	gnl|CDD|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	0
CP025990.1|AUS81351.1|6815567_6816773_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	1.78693e-57
CP025990.1|AUS81345.1|6807363_6808803_+|alkaline-phosphatase	gnl|CDD|293736	cd16012, ALP, Alkaline Phosphatase. Alkaline phosphatases are non-specific membrane-bound phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH. Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymatic activity. Mammalian alkaline phosphatase is divided into four isozymes depending upon the site of tissue expression. They are Intestinal ALP, Placental ALP, Germ cell ALP and tissue nonspecific alkaline phosphatase or liver/bone/kidney (L/B/K) ALP.	2.24214e-88
CP025990.1|AUS81343.1|6801339_6805083_+|hypothetical-protein	gnl|CDD|236657	PRK10150, PRK10150, beta-D-glucuronidase; Provisional.	3.76903e-39

Protein sequences

>CP025990.1|AUS81346.1|6808765_6809623_+|DUF4291-domain-containing-protein
MSPRSSSTSGDAEHSWSTRTDSGPPPLVAAPPREPGPVPGAQPCSSPSVTTRRPGRAPGANLRKSVAPAAGAPDARPVSLREVRANADASSVVVYQAYPAAIADPALRAGTFVAPFKQERMTWIKPSFRWMMYRCGWATKPGQERVLAVRISLEGLWWALRRSCASSHGAGRHPNREAWRRQLAESPVRVQWDPERDMDLNPLPQRSIQIGLGPEASRRYVDEWIVELTDVTELAREVGRLVRAGDQDGARALLPEEHPLTVPADIAERIDVTGPAPARTNGQGR
>CP025990.1|AUS81345.1|6807363_6808803_+|alkaline-phosphatase
MTEKAGRQRWRRPASVAAASALALTIGAPTAVGLEPGTAEHVAPLGFGPKNVIHLISDGMGYNHVDVASLWEHGTTAHQVRVDPDSGTTEHLPATPAQVYEDWPVQLGMSTYHDGHSYEADRAWAGFDYPSEDFTDSSAAGTALATGVRTYNGAIGLAPDRGPVKNLTERAQELGKASGVVSSVPFSHATPAAYVAHNPDRNDYHGIAKEMLFEHDINVVFGPGHPDFDEDGQRRDEPDHRYVDEWTWGAVQRGATAFDLVETPEEFAALAQSSNPPRHVLGVPQVAATLQYDRGGPDRTPDGRPVPGALPYTAPPVENVPTLADMTTSALAVLENASDEGLFLMIEGGAVDWASHDNDTARVIEEQIDFNRAVEAVVDWVEESSSWHETLVVVTADHETGYLAGPGADPTWTPVIGSAGQLPHVSWHSGNHTNALVPLFAKGPGASRLEQHADNIDPVRGRYLNNTDVAKVVFDFWGR
>CP025990.1|AUS81344.1|6805636_6806581_-|hypothetical-protein
MAAKHDNQWPVVVTDSCAGAYARWRGLTDHGAAKATLRRMVDELGEVTDQLPPQLAGRRSRSGFFLLVPDTLVLPLVRDSDGSTRWIATHCVPFPACDPPDLDALVALRGRELLARIHLTRHAVERFQERCGGAPDLDDAARQLRSTIAPTVRARRRPPGWCRTTPAEVFLVAGEHDQYCLPCRPGAVAELDATTCLHRASDLFERTGARLHAVCQVDRTRLPVGGEADRLLSSSVPLGGTLAWARPKWAAPHDGATWWVVFPNRVAAPVRWQPAKPNRPLRVLGVHDGRPWPVRLWSRIRHRLRRRGTGNRPG
>CP025990.1|AUS81343.1|6801339_6805083_+|hypothetical-protein
MLASPARPPPPSPPTRSRDTRASDHPDAQGLNERQRPGEVPVMHWSRQGADTPARPHPPRRRPTAILAAVVIMGGMAPLSTPGSADAEPATTTVNGQVVDADTGRPLPGAVVHVTEQTSTVRTDADGRFTVPEAPVDALALVAARQGYSFGWHPLEDPNAPVTLALEAETPDTVPHPDYPRPDFDRRAGVNGQWASLNGTWSLDFDPSDVGVDEGWHEGDHEWAHAVRVPFAYNSLAGIGEERRAGNQVYASQFAEARGTVWYQRDLTVPEDWPTDRGTLLRFGAVEWRAEVFLDGNRVGENDGGYSPFDVDLGPLRPGAEHSLVVRVEVPDNSATTPYPQGKQMGWYTDTGGIWQSVWIEPADSARLTTVHTTPEIDFDGREATAARVTVDVEARGAPDGTVELAVRAQDGEPGARAGQRQDGVSAPGLPVPVEPTVGEVVATATVTLVDGAGSAVIDVPDPRLWEPEAPWLYRVDASLTDQAGSDRVDTWFGLRTVSREWLPGHSPEEQDDPAEQYQYLFLNNRPVYLRSVLDQNFNPWGNYSYTGLYQGADLRGGELEDPGKGSVLFDLALTKQLGFNSVRPHIKVNDPLYYHWADVLGLLVWYDQPNFGYDGYGPEAERLWEEVLRDAVHRDYNHPSIVIWDAFNEAWGFNATPGGPIRDDAKPWIERMFDLTTDLVRGTRLVVDNSPCCENGHLVTDINDFHGYYSTWEEWAATVDRIVSNTYPGSTHNFEDGRTQSGQPLMNSEFGPWSGGREKDQEVATPFRYTAELFRAEQKMSGYLFTELTDLEWEWNGWAAYDRTLQVPGYLDADGAQGGVGLANADDVLLVGERPVQRLVGDDPIGLTVRSSLFSGRDLGETTLRWRVTGTDGTGAELPSSDWAEVPVSPETFAVTELTTVEVRPPDGFVAGRLDAELLSDGQPVASGQTVLAAWGAAAEQAAGTLALDPAGADVEWPQGSEVFSQDGASAVVGWGDGEFRWHLTVPEDLRDGGFDSAQLVLEAAASRPSLPRTSFPQTSERVFPTTLSATVSGAGTVVETEAVVLPDDPADARGALSHESGFHPGQYGYRVLLDLDVEDMRAAVADGEVTVTLRGAGGGLTVLGPRTGRFGVPPQLVLSEGAGLPGPAVAGGEPYLRTAEAAGVTTHLLAGDATAGAEAAMTVSVVNDSGEVVRDVRPAFVAPEGWTVEALGDHTVGELAPGEGAHLRYRVVPDGDGPVTVRTRAYYSTGEGRQVTEEPWELDLS
>CP025990.1|AUS81342.1|6799141_6800140_-|pirin
MPAVTVENTLELPRLAEAAPEGRQRPVRSVTTAPSGHEGEGFPVYRAFAGVSAGLLDPFIHLDQMGEVEYAPGEPKGTPWHPHRGFETVTYMMDGQMEHSDSHGGGGVIADGATQWMTAGSGILHIEKPPEHLVMSGGLFHGIQLWVNLPRANKWNPPQYQSIQGGETTLLSSPDGGALVRVIAGEVDGHHGPGNTFTPITLLHATLSPGARLVLPWRTDFNALVYALSGRGGVGEERHPLRAAQLAVFGAGDLLTIEATDHPDARTPDLDVLVLGGQPIREPVVQYGPFVMNSKAEVIQAFEDFQAGRMGVIPTERVPHAGHDQAPPAREN
>CP025990.1|AUS81341.1|6798024_6798855_+|oxidoreductase
MTTVPTLTLNNGVAMPQLGFGVYQVPDEEATATVRAALDAGYRSIDTAALYQNEIGTGRALAESGIPREELFVTTKLWNTDQGYDTTLRAFDASLERLGLDQVDLYLIHWPAPKLDRYVDTWRAFERIYSEDRTRAIGVSNFQPAHLARLFEASGIVPAVNQVELHPRLQQLAVREFDASNGIATEAWGPLGQGKGGLLDDPTLTQLAAKHGRTPAQIVLRWHIQLGNVVIPKSSTPSRMRENIDVFDFQLDADDMDSIAGMETGARGGPDPDVLS
>CP025990.1|AUS81340.1|6797281_6797653_-|thioredoxin
MSNTVELTKENFNEVVSENDFVLVDFWASWCGPCRQFAPVYDRVADKNPDLVFGKVDTEAQQELAGAFEIRSIPTLAIIRDNVLVFSQPGALPEAALEDVIRQARELDMDEVRRSVAESSKAE
>CP025990.1|AUS81339.1|6795284_6796916_+|PucR-family-transcriptional-regulator
MTVRGVSAAGAPGASLRQLLLALDDPLVELVAAPAGLDVVIGEVVILDPEDAPDTQRGDLILLIGARDASALPAVRAAARRGAAAVAVKVTSSGASDALRAAAVDAGVALLAVRPAARWEQVESLASGVVSRARVSADADEGEVLGDLFSTAQTVAHLTGGIVSIEDTAARVLAYSRSSGEVDELRRLSILGRQGPEPYLEMLREWGVYQRLRSGEDVVRIDERPDLGIRRRIAVGVHAGGRPLGAIWVQEGDEPLTEHAERSLLGAARVTALQLVRHRNEPSAGLRLRENLLAGLLNGRLDPSAAAGQLGVDSRRPAAVVAFASRVESPGAVVDRPELELRRDQLGNVISMHAAAFRRGALVSQLGTRTYALLPELSGSGEAAVVGLAREIISASRGIGLVVRAAVGSVVPELGGAADSRRQADRVLDAMAGDTAARVATIADWRAEVLVSETVDLLAEHPAIRDPRVTALRRHDERNNGSLVGSVVAYLESFGDVRAAARRLHVHPNTLRYRIRRAEEVSGLDLGDARQRLFTELQLRLRE
>CP025990.1|AUS81338.1|6793531_6795157_-|1-pyrroline-5-carboxylate-dehydrogenase
MDAVTNVPTPQNEPVLSYAPGTPERAELQAKLTELAAEPRELTLTIGGEQRMGGGRRIDVVQPHNHRHVLGTLGNATQQDATDAVEAARQAAPGWRALSYDDRAAVLLRAADLLSGPWRSTLNAATMLGQSKTAIQAEIDSACELADFWRFNVQYGRDILTEQPRSSAGVWNRMDHRPLEGFVYAITPFNFTAIAGNLPTAPALMGNTVVWKPAPTQSFAAHLTMRLLEAAGLPPGVINLVTGDGLDVSEVALAQPDLAGIHFTGSTATFQHLWGAVGANIANYRGYPRIVGETGGKDFVLAHPSADVDTLRTALVRGAFEFQGQKCSAASRAYIPRSLWTRLRDDLVAEVEGLTMGDVTDLSNFMGAVIDDRSFAKLSRVLDMARTDPTLEVIAGGTADDSEGYFVRPTVLVGTDPEHEVFRDEYFGPVLAVHVYDDADFEKVVRQMESVSPYALTGAVIAQDRSAIAYASEQLRFAAGNFYVNDKPTGAVVGQQPFGGARASGTNDKAGSVLNLLRWTSPRSLKETLVPPTSSGYPHQG
>CP025990.1|AUS81337.1|6792576_6793506_-|proline-dehydrogenase
MLRSILLAAGRSPLARTVVERTPATRYVVRRFVAGDTLDDAITATTALADDGLRITLDHLGEDTTDREQADATVDAYVRLLDRLRTANLAQAAEVSLKLSAVGQFLGSDGQRIALDNARRVCEAAAAAGTTVTLDMEDHTTTDSTLEVLRELRTDWPWVGAVLQAYLRRTEADCRDLAGPGSRVRLCKGAYKEPSSVAFQSRHEVDRAYVRCLDVLMSGEGYPMVATHDPRLVAITARLAGDNNRARDSYEYQMLYGIRPEEQLRLAGEGNTMRVYLPYGDEWYGYFMRRLAERPANVGFFLRALATKS
>CP025990.1|AUS81347.1|6810695_6811265_-|TetR/AcrR-family-transcriptional-regulator
MSPQRPLRADAARNRARIMATAHEQITEHGAGVSMERIAAASGVAVGTLYKHFPNKTDLVNAVIAASFAPVADDAEDSLRRAGQGAPAMEELTGFLTRLMDTVAHNQAVKAAAHALNTDHAVHPAMRDLEARVTSALGQLLRAAQAQGELRTDCTVDDLYLVLSTFPTDQAPAARVRWLALVLTGLIAR
>CP025990.1|AUS81348.1|6811355_6812309_+|short-chain-dehydrogenase
MTSTTAATRWTEDDVPDQDGRVAVVTGANSGLGWETARVLAAHGACVVLAVRDLDKGRQAMAAITDQVPGAQLGLQRLDLASLESVRAAAAELRDAHPRIDLLINNAGVMYTPRQKTQDGFDLQFGVNHLGHFALTGLLLEAMLPLPDSRVVTVSSLGHRIRADIHFDDPQWDRTYNRVAAYGQAKLANLMFTYELQRRLASHGTGTGTGTGTTIAAAAHPGGAATELMRNLPGPLRATAGLLVPLFTQTAAMGALPTLRAATDPAVTGGQYYGPTGMGGVRGYPRVVASSEKSHDRAVQQRLWTLSEQLTKVTFPV
>CP025990.1|AUS81349.1|6812614_6812866_-|hypothetical-protein
MWDEAAEGEFDMASQTCSKCGRTYDYGGECLYCWGLEAGTAVNAGREPRKPNASAPNSGCAVVGVLVLSGLITLMLLLDNIIA
>CP025990.1|AUS81350.1|6813331_6814435_+|LuxR-family-transcriptional-regulator
MANRRQRERQVLGDLRDLARAGVTARELFAELDGLLPSLMGFEAVCWHHTDPLTGLPTSMVSTTLDPRGMGPAMDLEFAGGDVATMAQMHARGDRVAALSQVTEGHPERSIRMREHLSTHGFGDELRLRFDLGEGTWGFAALMREKGSGPYSEEELRFAGQANRLISAALRRTYRPPTTLAVAAPVPAVIVLGSSDELVAADQPGQALLLELADSVFDVMAVPAVFLVLSRMARHAEADPTGIPAVMRLQTPAGQWIVLRGSVLHGIAAGQVVVTASTPTAAEIMPLVLSSHGLTRREQLVTAQVLRGGSTREIAKELSVAPVTVQDHLKSIFSKVGARSRGELVALLSLDGPRLDHSVPATSSDRR
>CP025990.1|AUS81351.1|6815567_6816773_+|IS110-family-transposase
MAVPELWAGVDAGKAAHHCTVIDTDGTKVLSRRVANNEADLLELIGDVRALAPDVLWAIDLNSGGAALLIALLVNHGQKLLYIPGRTVHRAAGTYRGDGKSDSKDAFVIADQARMRRDLHPVTAGDEIAVELRILTARRYDLAADRTRAINRLRAQLLEYFPALERAFDYSTSKAALVLLTGHQTPAALRERGREQLADWLRARKVRNSATVAAAAVAAAEAQFTTVPGEMTAAAMVARLAKGVMALDDEIAETDALIEGRFRRHRHAVAVLSMPGVGPLLGAEFIALTGGDMAAFGSADRLAGVAGLAPVPKDSGRVRGNLRRPRRYNRRLLRMFYLSAQVAARCCPTSKAFYDRKRREGKAHKQAVLALARRRLNVLWALIRDNRAFQTGTPQPEAAAA
>CP025990.1|AUS82064.1|6818616_6819069_+|hypothetical-protein
MRLGARPRRPRAQPARQEHPGQARAQGAQDVGGHPFTLLQRIQRTALGDVNTSFADRHFAGALSKPDQAVTTGMREAQPWLKKLWRDKTKRGLSVRLDRELARMTTLLEAAALPARFTTAQQSCFVLGYYHQKARYDEEMLAALEKKNKD
>CP025990.1|AUS82065.1|6820583_6821210_-|hypothetical-protein
MGRRPRPLDPPGTVTATDEHPFWVDDHGHWTHATDRTRGNTLLTPTGDHTTITHAHTYPHHHRVHNLTINAIHTYYVLAGETPVLVHNCGGGVTGAPRSADGKFSKRNGEPGRDGAADEANAWDQLEMDGAAVMRNEPAVSVPGMRARKYDGTVEINGQWYGIEVKGGTAKKNPHQRQFDDWLNSAGNTVTTSDGRTLVGVYDVWIDR
>CP025990.1|AUS81352.1|6821114_6821849_+|hypothetical-protein
MGPVAVVVDPEGVFVGGGDGARGVQWPWSSTQKGCSSVAVTVPGSWSGFGVWLTSTRVLGPSLVIVATTRWGPISPVSGSEARTSSPSWMSSMGVRVPSARRTRVPGTKLLTRQPALRRTAVASSRSRRQVRTRSTARLMPRRRSGILPSFVQGTALIRTQPQATMSALVKQFLMSSRPRTSDRTFPPASRTTSMTERVSRPSPPGTTSGPAAAGRGGGRRDVRVASAHAGSSPGSRPCSASRG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP025990_39	39.3|5574212|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574212-5574243	32	CP025990.1	4979502-4979533	0	1.0
CP025990_44	44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577596-6577628	33	CP025990.1	1355160-1355192	0	1.0
CP025990_43	43.1|6196005|19|CP025990|PILER-CR	6196005-6196023	19	CP025990.1	784854-784872	2	0.895

1. spacer 39.3|5574212|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to position: 4979502-4979533, mismatch: 0, identity: 1.0

gtcagttcctcttacgggaggtcctcccgaat	CRISPR spacer
gtcagttcctcttacgggaggtcctcccgaat	Protospacer
********************************

2. spacer 44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to position: 1355160-1355192, mismatch: 0, identity: 1.0

cggcagcttcgacaggacgttgttccggaccca	CRISPR spacer
cggcagcttcgacaggacgttgttccggaccca	Protospacer
*********************************

3. spacer 43.1|6196005|19|CP025990|PILER-CR matches to position: 784854-784872, mismatch: 2, identity: 0.895

acccgccgatctggcgatc	CRISPR spacer
acccgccggtctggcgctc	Protospacer
********.******* **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025990_28	28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214558-4214589	32	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	52817-52848	2	0.938
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3613207-3613238	2	0.938
CP025990_17	17.1|2049653|25|CP025990|CRISPRCasFinder	2049653-2049677	25	NZ_CP023779	Nocardia terpenica strain NC_YFY_NT001 plasmid p_NC_YFY_NT001, complete sequence	36599-36623	3	0.88
CP025990_17	17.1|2049653|25|CP025990|CRISPRCasFinder	2049653-2049677	25	NC_019789	Deinococcus peraridilitoris DSM 19664 plasmid pDEIPE01, complete sequence	470258-470282	3	0.88
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_AP018719	Sterolibacteriaceae bacterium J5B plasmid pSTJ1, complete sequence	126234-126260	3	0.889
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP020927	Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence	53171-53196	4	0.846
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP020927	Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence	188545-188570	4	0.846
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	177042-177067	4	0.846
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP030128	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence	263576-263601	4	0.846
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_AP017657	Sphingobium cloacae strain JCM 10874 plasmid pSCLO_3, complete sequence	143438-143463	4	0.846
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP005191	Sphingobium sp. MI1205 plasmid pMI2, complete sequence	172736-172761	4	0.846
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP011274	Planctomyces sp. SH-PL62 plasmid pPL62-1, complete sequence	32168-32193	4	0.846
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP046321	Gordonia bronchialis strain FDAARGOS_676 plasmid unnamed1, complete sequence	6106-6137	4	0.875
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_013442	Gordonia bronchialis DSM 43247 plasmid pGBRO01, complete sequence	1859-1890	4	0.875
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1273935-1273961	4	0.852
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP054603	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed4, complete sequence	57654-57680	4	0.852
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	101109-101135	4	0.852
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1046849-1046875	4	0.852
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1085530-1085556	4	0.852
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	303944-303970	4	0.852
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NC_010815	Geobacter lovleyi SZ plasmid pGLOV01, complete sequence	27775-27801	4	0.852
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP046332	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2	117180-117214	5	0.857
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NC_006466	Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence	71806-71840	5	0.857
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP038146	Streptomyces sp. S501 plasmid unnamed, complete sequence	171039-171070	5	0.844
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_021347	Rhodococcus phage E3, complete genome	94406-94436	5	0.839
CP025990_28	28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214619-4214650	32	NZ_CP007516	Rubrobacter radiotolerans strain RSPS-4 plasmid 2, complete sequence	146868-146899	5	0.844
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_CP015623	Corynebacterium crudilactis strain JZ16 plasmid pCRULAC1, complete sequence	18446-18477	5	0.844
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	773775-773807	5	0.848
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	221509-221534	5	0.808
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	1475419-1475450	5	0.844
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	257337-257368	5	0.844
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_AP021845	Azospira sp. I09 plasmid pAZI09, complete sequence	296502-296528	5	0.815
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP031851	Klebsiella pneumoniae strain 121 plasmid pKP121-2, complete sequence	8528-8554	5	0.815
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	AY328852	Vibrio parahaemolyticus phage VP16T, partial sequence	34935-34961	5	0.815
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	1475419-1475450	5	0.844
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	34601-34635	6	0.829
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	295958-295989	6	0.812
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NC_015382	Burkholderia gladioli BSR3 plasmid bgla_1p, complete sequence	119263-119294	6	0.812
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_CP017591	Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ10, complete sequence	60556-60587	6	0.812
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_CP049116	Pantoea stewartii strain ZJ-FGZX1 plasmid unnamed1, complete sequence	26587-26618	6	0.812
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	MN693826	Marine virus AFVG_250M656, complete genome	32778-32808	6	0.806
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	MN694627	Marine virus AFVG_250M1035, complete genome	32747-32777	6	0.806
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	MN693710	Marine virus AFVG_250M1034, complete genome	3843-3873	6	0.806
CP025990_24	24.5|3572196|31|CP025990|CRISPRCasFinder	3572196-3572226	31	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	509341-509371	6	0.806
CP025990_26	26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder	3610423-3610456	34	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	389608-389641	6	0.824
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP020900	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence	985939-985969	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1688546-1688576	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013526	Rhizobium phaseoli strain R744 plasmid pRphaR744d, complete sequence	590622-590652	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	604421-604451	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013589	Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence	593165-593195	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	632491-632521	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	586514-586544	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013531	Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence	618817-618847	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013536	Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence	311211-311241	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	607105-607135	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	600937-600967	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	604421-604451	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013584	Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence	618817-618847	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	586514-586544	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_010997	Rhizobium etli CIAT 652 plasmid pC, complete sequence	592362-592392	6	0.806
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP016617	Microvirga ossetica strain V5/3m plasmid unnamed1, complete sequence	510066-510096	6	0.806
CP025990_30	30.1|4939798|34|CP025990|CRISPRCasFinder,CRT	4939798-4939831	34	NZ_CP006570	Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence	431942-431975	6	0.824
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	2552491-2552522	6	0.812
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	532355-532386	6	0.812
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	1074813-1074844	6	0.812
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	543701-543732	6	0.812
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_CP016078	Actinoalloteichus sp. GBA129-24 plasmid pGBA129-24a, complete sequence	53665-53697	6	0.818
CP025990_33	33.4|4974253|33|CP025990|CRISPRCasFinder,CRT	4974253-4974285	33	NZ_CP013744	Streptomyces sp. CdTB01 plasmid unnamed, complete sequence	162742-162774	6	0.818
CP025990_33	33.7|4974438|33|CP025990|CRISPRCasFinder,CRT	4974438-4974470	33	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	147057-147089	6	0.818
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP004365	Komagataeibacter xylinus E25 plasmid pGX5, complete sequence	303945-303970	6	0.769
CP025990_33	33.8|4974319|26|CP025990|PILER-CR	4974319-4974344	26	NZ_CP041350	Komagataeibacter xylinus strain CGMCC 17276 plasmid pB, complete sequence	77156-77181	6	0.769
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	236184-236215	6	0.812
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	192752-192783	6	0.812
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP041206	Rhizobium sp. NIBRBAC000502774 plasmid pMK-3, complete sequence	354871-354902	6	0.812
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NC_019677	Nostoc sp. PCC 7524 plasmid pNOS7524.01, complete sequence	64119-64150	6	0.812
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP021356	Rhodococcus sp. S2-17 plasmid pRB29, complete sequence	200873-200904	6	0.812
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	183133-183164	6	0.812
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP054615	Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence	148949-148980	6	0.812
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	49972-50003	6	0.812
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	MT316461	Streptomyces phage Galactica, complete genome	77313-77344	6	0.812
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP021373	Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence	26019-26045	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	820929-820955	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	243188-243214	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	829265-829291	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	18255-18281	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	610741-610767	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	490131-490157	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	585442-585468	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1282049-1282075	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	128181-128207	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	128181-128207	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1819620-1819646	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1842587-1842613	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1879558-1879584	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1901792-1901818	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1527425-1527451	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1809989-1810015	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	417224-417250	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	785247-785273	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1887865-1887891	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1597499-1597525	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1826941-1826967	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1827035-1827061	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1821812-1821838	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1890528-1890554	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1823164-1823190	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1899344-1899370	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1890495-1890521	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1796817-1796843	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1874316-1874342	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1889238-1889264	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1790250-1790276	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1797129-1797155	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1874316-1874342	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1889337-1889363	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1796817-1796843	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1790899-1790925	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1796020-1796046	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1874316-1874342	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1874316-1874342	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1874316-1874342	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1889333-1889359	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1951194-1951220	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1889322-1889348	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1790275-1790301	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1805442-1805468	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1786078-1786104	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1847185-1847211	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1877094-1877120	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1871631-1871657	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1889322-1889348	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1790275-1790301	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1797128-1797154	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1824237-1824263	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1890318-1890344	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1790275-1790301	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1790275-1790301	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1889333-1889359	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1874321-1874347	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1889344-1889370	6	0.778
CP025990_37	37.2|5319802|27|CP025990|PILER-CR	5319802-5319828	27	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1889145-1889171	6	0.778
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	236184-236215	6	0.812
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	192752-192783	6	0.812
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	338575-338607	6	0.818
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	7266-7298	6	0.818
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MT952005	Aeromonas phage BUCT551, complete genome	9656-9688	6	0.818
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP024940	Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence	1144720-1144752	6	0.818
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	MT711977	Streptomyces phage Dagobah, complete genome	16268-16299	6	0.812
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	325547-325578	6	0.812
CP025990_42	42.3|5600696|34|CP025990|CRISPRCasFinder,CRT	5600696-5600729	34	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	680759-680792	6	0.824
CP025990_42	42.6|5600696|33|CP025990|PILER-CR	5600696-5600728	33	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	680760-680792	6	0.818
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	NC_028802	Mycobacterium phage UnionJack, complete genome	38473-38500	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MG099937	Mycobacterium phage Aragog, complete genome	38528-38555	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MG099938	Mycobacterium phage Archetta, complete genome	38938-38965	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MH338241	Mycobacterium phage Tarynearal, complete genome	38469-38496	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MN586062	Mycobacterium phage Lev2, complete genome	38663-38690	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	NC_022973	Mycobacterium phage Conspiracy, complete genome	38750-38777	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	KF493882	Mycobacterium phage Jovo, complete genome	39031-39058	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	NC_041984	Mycobacterium phage Tiger, complete genome	38329-38356	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MG099949	Mycobacterium phage Phlorence, complete genome	38408-38435	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MG099944	Mycobacterium phage ForGetIt, complete genome	38775-38802	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	MG099934	Mycobacterium phage AgentM, complete genome	38508-38535	6	0.786
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	Z18946	Mycobacterium phage L5 complete genome	31909-31936	6	0.786
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_CP013109	Sinorhizobium americanum strain CFNEI 73 plasmid B, complete sequence	5786-5818	7	0.788
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_CP013053	Sinorhizobium americanum CCGM7 plasmid B, complete sequence	5786-5818	7	0.788
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_KU356480	Vibrio parahaemolyticus strain VPS92 plasmid pVPS92-VEB, complete sequence	117252-117284	7	0.788
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_CP053812	Vibrio cholerae strain W6G plasmid pW6G, complete sequence	242364-242396	7	0.788
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_CP053815	Vibrio cholerae strain W7G plasmid pW7G, complete sequence	198196-198228	7	0.788
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_LN831184	Vibrio cholerae isolate V. cholerae 116-14 plasmid pNDM-116-14, complete sequence	50157-50189	7	0.788
CP025990_3	3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135635-135667	33	KU530220	Streptomyces phage Xkcd426, complete genome	14906-14938	7	0.788
CP025990_3	3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135635-135667	33	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	588865-588897	7	0.788
CP025990_4	4.1|207439|29|CP025990|CRT	207439-207467	29	NZ_CP049358	Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence	252444-252472	7	0.759
CP025990_4	4.1|207439|29|CP025990|CRT	207439-207467	29	NZ_CP031159	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence	226640-226668	7	0.759
CP025990_4	4.1|207439|29|CP025990|CRT	207439-207467	29	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	45897-45925	7	0.759
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	301115-301149	7	0.8
CP025990_6	6.12|408965|35|CP025990|CRISPRCasFinder,CRT	408965-408999	35	NZ_CP051543	Paracoccus sanguinis strain OM2164 plasmid pPspOM122, complete sequence	80826-80860	7	0.8
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_048768	Gordonia phage Chelms, complete genome	55882-55913	7	0.781
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	MT986029	Gordonia phage Linetti, complete genome	56904-56935	7	0.781
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	812010-812041	7	0.781
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	590819-590850	7	0.781
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	812010-812041	7	0.781
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_LR027555	Epibacterium mobile isolate EPIB1 plasmid 3, complete sequence	51954-51985	7	0.781
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	800343-800374	7	0.781
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP039693	Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence	244118-244149	7	0.781
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	525492-525523	7	0.781
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	JQ067093	Pseudomonas phage PaMx74, partial genome	10393-10424	7	0.781
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP040096	Pantoea sp. SO10 plasmid unnamed1, complete sequence	505636-505667	7	0.781
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	562757-562788	7	0.781
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	653073-653104	7	0.781
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	395470-395501	7	0.781
CP025990_8	8.7|478685|33|CP025990|PILER-CR,CRT	478685-478717	33	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	15704-15736	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP021029	Rhizobium sp. TAL182 plasmid pRetTAL182e, complete sequence	312791-312823	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013600	Rhizobium sp. N741 plasmid pRspN741e, complete sequence	464618-464650	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013504	Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence	464618-464650	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013510	Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence	463059-463091	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013521	Rhizobium sp. N113 plasmid pRspN113d, complete sequence	467306-467338	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013494	Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence	461425-461457	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013515	Rhizobium sp. N1314 plasmid pRspN1314d, complete sequence	308105-308137	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013594	Rhizobium sp. N871 plasmid pRspN871d, complete sequence	464618-464650	7	0.788
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP013605	Rhizobium sp. N731 plasmid pRspN731d, complete sequence	308099-308131	7	0.788
CP025990_8	8.11|478929|33|CP025990|PILER-CR,CRT	478929-478961	33	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	295958-295990	7	0.788
CP025990_8	8.12|478990|33|CP025990|PILER-CR,CRT	478990-479022	33	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	439722-439754	7	0.788
CP025990_8	8.12|478990|33|CP025990|PILER-CR,CRT	478990-479022	33	NZ_CP046575	Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence	3533-3565	7	0.788
CP025990_9	9.16|482147|32|CP025990|CRT	482147-482178	32	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	172470-172501	7	0.781
CP025990_12	12.13|718421|36|CP025990|PILER-CR,CRISPRCasFinder	718421-718456	36	NZ_CP016288	Rhizobium leguminosarum strain Vaf10 plasmid unnamed7, complete sequence	73751-73786	7	0.806
CP025990_13	13.4|792104|35|CP025990|PILER-CR,CRT	792104-792138	35	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	16904-16938	7	0.8
CP025990_13	13.17|792105|34|CP025990|CRISPRCasFinder	792105-792138	34	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	482690-482723	7	0.794
CP025990_13	13.17|792105|34|CP025990|CRISPRCasFinder	792105-792138	34	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	16905-16938	7	0.794
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_CP013918	Sphingomonas sp. LK11 plasmid unnamed1, complete sequence	2289-2320	7	0.781
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_CP013918	Sphingomonas sp. LK11 plasmid unnamed1, complete sequence	26232-26263	7	0.781
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_CP044976	Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence	233374-233405	7	0.781
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	465370-465401	7	0.781
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	NZ_AP022849	Bosea sp. ANAM02 plasmid pANAM02, complete sequence	326444-326475	7	0.781
CP025990_22	22.9|3492088|34|CP025990|CRT	3492088-3492121	34	NZ_CP025410	Paracoccus sp. BM15 plasmid pBM152, complete sequence	35005-35038	7	0.794
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	643514-643544	7	0.774
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	233238-233268	7	0.774
CP025990_24	24.1|3572195|32|CP025990|PILER-CR	3572195-3572226	32	NC_012521	Rhodococcus opacus B4 plasmid pROB02, complete sequence	130595-130626	7	0.781
CP025990_24	24.1|3572195|32|CP025990|PILER-CR	3572195-3572226	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	509341-509372	7	0.781
CP025990_24	24.5|3572196|31|CP025990|CRISPRCasFinder	3572196-3572226	31	NC_012521	Rhodococcus opacus B4 plasmid pROB02, complete sequence	130596-130626	7	0.774
CP025990_24	24.8|3572379|31|CP025990|CRISPRCasFinder	3572379-3572409	31	NZ_CP020952	Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence	65089-65119	7	0.774
CP025990_25	25.5|3609535|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	3609535-3609567	33	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	373432-373464	7	0.788
CP025990_25	25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT	3609657-3609687	31	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	926041-926071	7	0.774
CP025990_25	25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT	3609657-3609687	31	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	887083-887113	7	0.774
CP025990_26	26.3|3610419|38|CP025990|CRT	3610419-3610456	38	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	389608-389645	7	0.816
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	2258399-2258429	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP020568	Kitasatospora aureofaciens strain DM-1 plasmid unnamed1, complete sequence	189826-189856	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	376650-376680	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	654030-654060	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1771634-1771664	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN234205	Mycobacterium phage Veliki, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH727544	Mycobacterium phage Dalmuri, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH001453	Mycobacterium phage Adonis, complete genome	2496-2526	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	KX683428	Mycobacterium phage TBond007, complete genome	2130-2160	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	JF704105	Mycobacterium phage Adephagia, complete sequence	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN234182	Mycobacterium phage Geraldini, complete genome	2508-2538	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN234198	Mycobacterium phage Zavala, complete genome	2464-2494	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF140412	Mycobacterium phage Jeckyll, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	KY380102	Mycobacterium phage CREW, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	KX585253	Mycobacterium phage HedwigODU, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN234230	Mycobacterium phage Atiba, complete genome	2448-2478	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF140430	Mycobacterium phage Tachez, complete genome	2448-2478	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF140428	Mycobacterium phage Slimphazie, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MK460247	Mycobacterium phage YoureAdopted, complete genome	2455-2485	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	JN185608	Mycobacterium virus JAWS, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN234231	Mycobacterium phage Rapunzel97, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF373841	Mycobacterium phage Hurricane, complete genome	2386-2416	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_014458	Mycobacterium phage Angelica, complete genome	2467-2497	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN908692	Mycobacterium Phage BGlluviae, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_023747	Mycobacterium phage BarrelRoll, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	KR080206	Mycobacterium phage ShedlockHolmes, complete genome	2380-2410	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH536821	Mycobacterium phage Homura, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_014459	Mycobacterium virus CrimD, complete genome	2454-2484	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF668267	Mycobacterium phage Apocalypse, complete genome	2463-2493	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH697578	Mycobacterium phage Belladonna, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH509444	Mycobacterium phage BEEST, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN369742	Mycobacterium phage Spock, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_042325	Mycobacterium virus Pixie, complete genome	2131-2161	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MK112537	Mycobacterium Phage Capricorn, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NC_026603	Mycobacterium phage Keshu, complete genome	2365-2395	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN369746	Mycobacterium phage Inky, complete genome	2529-2559	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH051246	Mycobacterium phage ActinUp, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MN234197	Mycobacterium phage Ramen, complete genome	2479-2509	7	0.774
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MH371113	Mycobacterium phage Beezoo, complete genome	2508-2538	7	0.774
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	190083-190114	7	0.781
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	1452561-1452592	7	0.781
CP025990_28	28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214619-4214650	32	NZ_CP029362	Streptomyces globisporus strain TFH56 plasmid pTFSG1, complete sequence	123612-123643	7	0.781
CP025990_28	28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214619-4214650	32	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	643576-643607	7	0.781
CP025990_28	28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214619-4214650	32	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	496291-496322	7	0.781
CP025990_28	28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214619-4214650	32	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	552964-552995	7	0.781
CP025990_31	31.1|4968642|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4968642-4968673	32	NZ_CP026653	Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence	64982-65013	7	0.781
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_018532	Arthrobacter sp. Rue61a plasmid p232, complete sequence	37347-37378	7	0.781
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	186952-186983	7	0.781
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	MT108725	Pseudomonas phage Epa5, complete genome	40278-40309	7	0.781
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	331099-331130	7	0.781
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	46694-46725	7	0.781
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	858561-858592	7	0.781
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	954562-954593	7	0.781
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1961151-1961182	7	0.781
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_LR134455	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence	64466-64498	7	0.788
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_CP040765	Paracoccus sp. 2251 plasmid unnamed1, complete sequence	209848-209880	7	0.788
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	627542-627574	7	0.788
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	704364-704396	7	0.788
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1108706-1108738	7	0.788
CP025990_33	33.4|4974253|33|CP025990|CRISPRCasFinder,CRT	4974253-4974285	33	NZ_CP011248	Agrobacterium tumefaciens strain Ach5 plasmid pAt, complete sequence	306023-306055	7	0.788
CP025990_33	33.4|4974253|33|CP025990|CRISPRCasFinder,CRT	4974253-4974285	33	NZ_CP032919	Agrobacterium tumefaciens strain 15955 plasmid pAt15955, complete sequence	576733-576765	7	0.788
CP025990_33	33.4|4974253|33|CP025990|CRISPRCasFinder,CRT	4974253-4974285	33	NZ_CP033029	Agrobacterium tumefaciens strain A6 plasmid pAtA6, complete sequence	576816-576848	7	0.788
CP025990_33	33.4|4974253|33|CP025990|CRISPRCasFinder,CRT	4974253-4974285	33	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	302277-302309	7	0.788
CP025990_33	33.7|4974438|33|CP025990|CRISPRCasFinder,CRT	4974438-4974470	33	NZ_CP035513	Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence	10963-10995	7	0.788
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	62341-62372	7	0.781
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1267200-1267231	7	0.781
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP020613	Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence	15701-15732	7	0.781
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	141991-142022	7	0.781
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP022751	Sphingobium hydrophobicum strain C1 plasmid p5, complete sequence	4252-4283	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	461910-461941	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_AP019820	Enterobacter hormaechei subsp. hoffmannii strain OIPH-N069 plasmid pN069_3, complete sequence	7670-7701	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	MK524177	Escherichia phage PHB10, complete genome	49350-49381	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	238709-238740	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	CP003952	Rhodococcus opacus PD630 plasmid 3, complete sequence	7755-7786	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_004680	Mycobacterium phage Che8, complete genome	25074-25105	7	0.781
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	AY129330	Mycobacterium virus Che8, complete genome	25074-25105	7	0.781
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	62341-62372	7	0.781
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1267200-1267231	7	0.781
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP020613	Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence	15701-15732	7	0.781
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MK838113	Aeromonas phage LAh_7, complete genome	9860-9892	7	0.788
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP024582	Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence	360119-360151	7	0.788
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1172175-1172207	7	0.788
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP021083	Deinococcus ficus strain CC-FR2-10 plasmid pDFI2, complete sequence	120785-120816	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP024426	Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence	101536-101567	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP020445	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence	41357-41388	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	55207-55238	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	366141-366172	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	989576-989607	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	111560-111591	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	571734-571765	7	0.781
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1448549-1448580	7	0.781
CP025990_42	42.2|5600635|33|CP025990|CRISPRCasFinder,CRT	5600635-5600667	33	NZ_CP048283	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence	171213-171245	7	0.788
CP025990_43	43.2|6196066|30|CP025990|PILER-CR	6196066-6196095	30	NZ_CP042535	Citrobacter freundii strain E51 plasmid pE51_001, complete sequence	138526-138555	7	0.767
CP025990_43	43.2|6196066|30|CP025990|PILER-CR	6196066-6196095	30	NZ_CP026546	Cupriavidus metallidurans strain Ni-2 plasmid unnamed2	144457-144486	7	0.767
CP025990_43	43.5|6196115|33|CP025990|CRISPRCasFinder,CRT	6196115-6196147	33	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	781613-781645	7	0.788
CP025990_44	44.3|6577413|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577413-6577445	33	MH834619	Arthrobacter phage Maureen, complete genome	361-393	7	0.788
CP025990_44	44.3|6577413|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577413-6577445	33	NC_048115	Arthrobacter phage Liebe, complete genome	361-393	7	0.788
CP025990_44	44.4|6577474|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577474-6577506	33	NZ_AP022566	Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence	180771-180803	7	0.788
CP025990_45	45.1|6584161|33|CP025990|CRISPRCasFinder,CRT	6584161-6584193	33	MT451981	Streptomyces phage Vondra, complete genome	1039-1071	7	0.788
CP025990_45	45.1|6584161|33|CP025990|CRISPRCasFinder,CRT	6584161-6584193	33	MT451982	Streptomyces phage Cumberbatch, complete genome	1039-1071	7	0.788
CP025990_45	45.2|6584222|34|CP025990|CRISPRCasFinder,CRT,PILER-CR	6584222-6584255	34	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	77599-77632	7	0.794
CP025990_46	46.1|6740139|28|CP025990|CRISPRCasFinder	6740139-6740166	28	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	20843-20870	7	0.75
CP025990_1	1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123621-123653	33	NZ_CP024309	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3b, complete sequence	2752-2784	8	0.758
CP025990_1	1.2|123682|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123682-123714	33	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	96584-96616	8	0.758
CP025990_1	1.4|123804|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123804-123836	33	KP282680	Sulfolobales Virus YNP2 strain SYV2, complete genome	3835-3867	8	0.758
CP025990_2	2.4|133695|33|CP025990|PILER-CR,CRT	133695-133727	33	NZ_CP014598	Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence	224907-224939	8	0.758
CP025990_2	2.4|133695|33|CP025990|PILER-CR,CRT	133695-133727	33	NZ_CP038031	Rhodococcus ruber strain R1 plasmid unnamed1, complete sequence	73935-73967	8	0.758
CP025990_2	2.4|133695|33|CP025990|PILER-CR,CRT	133695-133727	33	NC_005073	Rhodococcus erythropolis linear plasmid pBD2, complete sequence	206056-206088	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1508737-1508769	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	89840-89872	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1885200-1885232	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1515089-1515121	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1511822-1511854	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1511322-1511354	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	561807-561839	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	312853-312885	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1156603-1156635	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	446531-446563	8	0.758
CP025990_3	3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135390-135422	33	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	446531-446563	8	0.758
CP025990_3	3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	135635-135667	33	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	646076-646108	8	0.758
CP025990_4	4.1|207439|29|CP025990|CRT	207439-207467	29	NC_017791	Deinococcus gobiensis I-0 plasmid P2, complete sequence	185003-185031	8	0.724
CP025990_4	4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207496-207528	33	NZ_CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	503107-503139	8	0.758
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	NZ_CP023721	Rhodococcus sp. H-CA8f plasmid unnamed, complete sequence	105460-105492	8	0.758
CP025990_4	4.9|207925|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207925-207958	34	MG925349	Mycobacterium phage Mendokysei, complete genome	30946-30979	8	0.765
CP025990_4	4.10|207987|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207987-208019	33	NZ_AP022849	Bosea sp. ANAM02 plasmid pANAM02, complete sequence	479298-479330	8	0.758
CP025990_4	4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	208109-208141	33	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1442957-1442989	8	0.758
CP025990_4	4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	208109-208141	33	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	2169846-2169878	8	0.758
CP025990_5	5.1|369283|33|CP025990|CRISPRCasFinder	369283-369315	33	CP006582	Mesorhizobium huakuii 7653R plasmid pMHa, complete sequence	64632-64664	8	0.758
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	707042-707076	8	0.771
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NC_002699	Frankia sp. CpI1 plasmid pFQ12, complete plasmid sequence	2105-2139	8	0.771
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	1154495-1154526	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP041043	Paracoccus sp. AK26 plasmid pAK3, complete sequence	85300-85331	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	1165285-1165316	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	596618-596649	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	626960-626991	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1130225-1130256	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	664154-664185	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	719775-719806	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1086127-1086158	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	1153961-1153992	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	213700-213731	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1767641-1767672	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1507812-1507843	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	270234-270265	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	1062551-1062582	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	1472189-1472220	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	277858-277889	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1521586-1521617	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	1318899-1318930	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	1119478-1119509	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	801273-801304	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	574344-574375	8	0.75
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	596620-596651	8	0.75
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	203319-203350	8	0.75
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NC_012854	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence	180399-180430	8	0.75
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP020900	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence	543608-543639	8	0.75
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP015232	Epibacterium mobile F1926 plasmid unnamed2, complete sequence	3457-3488	8	0.75
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NC_042088	Gordonia phage Gustav, complete genome	34214-34245	8	0.75
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP026382	Sphingopyxis sp. MG plasmid pCMS1, complete sequence	63488-63519	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	800891-800922	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP012575	Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence	11599-11630	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP012575	Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence	42311-42342	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP047052	Clavibacter michiganensis subsp. michiganensis strain MSF322 plasmid pMSF2, complete sequence	60474-60505	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	CP048046	Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence	11158-11189	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	CP048046	Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence	41853-41884	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_007961	Nitrobacter hamburgensis X14 plasmid 3, complete sequence	24360-24391	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP048050	Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence	98052-98083	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP048050	Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence	128756-128787	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP048048	Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence	5786-5817	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP048048	Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence	118105-118136	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_AP014686	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence	187379-187410	8	0.75
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_049489	Arthrobacter phage DrYang, complete genome	25011-25042	8	0.75
CP025990_8	8.7|478685|33|CP025990|PILER-CR,CRT	478685-478717	33	NZ_CP041043	Paracoccus sp. AK26 plasmid pAK3, complete sequence	85299-85331	8	0.758
CP025990_8	8.11|478929|33|CP025990|PILER-CR,CRT	478929-478961	33	JQ067093	Pseudomonas phage PaMx74, partial genome	10392-10424	8	0.758
CP025990_8	8.11|478929|33|CP025990|PILER-CR,CRT	478929-478961	33	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1178717-1178749	8	0.758
CP025990_8	8.11|478929|33|CP025990|PILER-CR,CRT	478929-478961	33	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	780442-780474	8	0.758
CP025990_8	8.11|478929|33|CP025990|PILER-CR,CRT	478929-478961	33	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	437703-437735	8	0.758
CP025990_8	8.12|478990|33|CP025990|PILER-CR,CRT	478990-479022	33	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	800890-800922	8	0.758
CP025990_9	9.15|482082|34|CP025990|CRT	482082-482115	34	DQ372923	Bacteriophage mu1/6, complete genome	27494-27527	8	0.765
CP025990_9	9.15|482082|34|CP025990|CRT	482082-482115	34	NC_007967	Streptomyces phage mu1/6, complete genome	27494-27527	8	0.765
CP025990_10	10.1|554801|33|CP025990|CRT	554801-554833	33	NZ_CP016620	Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence	444682-444714	8	0.758
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NZ_CP041653	Streptomyces sp. RLB1-9 plasmid pRLB1-9.1, complete sequence	88410-88443	8	0.765
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NC_004719	Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence	35984-36017	8	0.765
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NC_004719	Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence	36080-36113	8	0.765
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NC_004719	Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence	36464-36497	8	0.765
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NC_004719	Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence	36752-36785	8	0.765
CP025990_11	11.4|711870|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711870-711902	33	NZ_CP039220	Piscirickettsia salmonis strain NVI 5692 plasmid unnamed1, complete sequence	82779-82811	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NZ_CP051470	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence	64160-64192	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NC_011960	Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence	13767-13799	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NZ_CP030273	Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence	22536-22568	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	CP047033	Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence	16212-16244	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NC_009040	Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence	99322-99354	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NZ_CP015290	Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence	48526-48558	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NZ_CP047039	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence	16201-16233	8	0.758
CP025990_11	11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711992-712024	33	NZ_CP015213	Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence	60006-60038	8	0.758
CP025990_11	11.7|712053|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	712053-712085	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1096324-1096356	8	0.758
CP025990_13	13.4|792104|35|CP025990|PILER-CR,CRT	792104-792138	35	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	482689-482723	8	0.771
CP025990_13	13.17|792105|34|CP025990|CRISPRCasFinder	792105-792138	34	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	264005-264038	8	0.765
CP025990_13	13.17|792105|34|CP025990|CRISPRCasFinder	792105-792138	34	NZ_CP045326	Mycobacterium sp. THAF192 plasmid pTHAF192_a, complete sequence	68053-68086	8	0.765
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	105663-105697	8	0.771
CP025990_14	14.2|1142214|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142214-1142249	36	JQ067089	Pseudomonas phage PaMx28, partial genome	41071-41106	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417913	Uncultured Caudovirales phage clone 9S_2, partial genome	13185-13220	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417918	Uncultured Caudovirales phage clone 7F_17, partial genome	8271-8306	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417915	Uncultured Caudovirales phage clone 8AX_8, partial genome	22082-22117	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417914	Uncultured Caudovirales phage clone 8S_2, partial genome	18737-18772	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417896	Uncultured Caudovirales phage clone 3S_18, partial genome	13835-13870	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417912	Uncultured Caudovirales phage clone 10AX_4, partial genome	21246-21281	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417910	Uncultured Caudovirales phage clone 2AX_5, partial genome	11230-11265	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417916	Uncultured Caudovirales phage clone 7S_13, partial genome	20008-20043	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417911	Uncultured Caudovirales phage clone 9AX_3, partial genome	27146-27181	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417920	Uncultured Caudovirales phage clone 10F_8, partial genome	31236-31271	8	0.778
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	MF417898	Uncultured Caudovirales phage clone 7AX_6, partial genome	22644-22679	8	0.778
CP025990_18	18.2|2981929|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981929-2981960	32	NZ_CP017148	Bosea vaviloviae strain Vaf18 plasmid unnamed1, complete sequence	300674-300705	8	0.75
CP025990_18	18.4|2982051|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2982051-2982082	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	508490-508521	8	0.75
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	111396-111427	8	0.75
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	117318-117349	8	0.75
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	810613-810644	8	0.75
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	579140-579171	8	0.75
CP025990_22	22.9|3492088|34|CP025990|CRT	3492088-3492121	34	NZ_CP014598	Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence	156113-156146	8	0.765
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1554079-1554111	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1050332-1050364	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NC_014642	Achromobacter xylosoxidans A8 plasmid pA82, complete sequence	42386-42418	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	550777-550809	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1363156-1363188	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1345673-1345705	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	169688-169720	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP026974	Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence	256531-256563	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1581608-1581640	8	0.758
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	MN586028	Gordonia phage MelBins, complete genome	13969-14001	8	0.758
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	492467-492497	8	0.742
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	767467-767497	8	0.742
CP025990_24	24.4|3572378|32|CP025990|PILER-CR	3572378-3572409	32	NZ_CP020952	Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence	65088-65119	8	0.75
CP025990_24	24.6|3572257|31|CP025990|CRISPRCasFinder	3572257-3572287	31	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	253212-253242	8	0.742
CP025990_24	24.6|3572257|31|CP025990|CRISPRCasFinder	3572257-3572287	31	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	447626-447656	8	0.742
CP025990_24	24.8|3572379|31|CP025990|CRISPRCasFinder	3572379-3572409	31	CP052219	Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-2, complete sequence	64691-64721	8	0.742
CP025990_24	24.8|3572379|31|CP025990|CRISPRCasFinder	3572379-3572409	31	NZ_CP024642	Klebsiella michiganensis strain F107 plasmid unnamed2, complete sequence	123025-123055	8	0.742
CP025990_25	25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT	3609657-3609687	31	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	1628098-1628128	8	0.742
CP025990_25	25.9|3609777|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	3609777-3609809	33	MH588547	Caulobacter phage CcrSC, complete genome	273368-273400	8	0.758
CP025990_26	26.9|3610362|33|CP025990|PILER-CR,CRISPRCasFinder	3610362-3610394	33	NZ_LR134450	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence	274250-274282	8	0.758
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_AP017899	Sphingopyxis sp. FD7 plasmid pSFD01, complete sequence	154819-154849	8	0.742
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	476234-476264	8	0.742
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	201694-201724	8	0.742
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP039640	Azospirillum sp. TSH100 plasmid p1, complete sequence	202545-202575	8	0.742
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP045288	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff1, complete sequence	140946-140976	8	0.742
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MG962364	Mycobacterium phage Deby, complete genome	2467-2497	8	0.742
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF919532	Mycobacterium phage Sulley, complete genome	2467-2497	8	0.742
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NC_011984	Agrobacterium vitis S4 plasmid pAtS4c, complete sequence	145338-145369	8	0.75
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	373278-373309	8	0.75
CP025990_28	28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214558-4214589	32	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	687316-687347	8	0.75
CP025990_28	28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214558-4214589	32	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	855189-855220	8	0.75
CP025990_28	28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214558-4214589	32	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	51679-51710	8	0.75
CP025990_28	28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214619-4214650	32	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	340217-340248	8	0.75
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1077902-1077934	8	0.758
CP025990_30	30.1|4939798|34|CP025990|CRISPRCasFinder,CRT	4939798-4939831	34	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	129644-129677	8	0.765
CP025990_30	30.1|4939798|34|CP025990|CRISPRCasFinder,CRT	4939798-4939831	34	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	18017-18050	8	0.765
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	38265-38296	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1774851-1774882	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP035092	Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence	595094-595125	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_008688	Paracoccus denitrificans PD1222 plasmid 1, complete sequence	188627-188658	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	202499-202530	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP017079	Novosphingobium resinovorum strain SA1 plasmid pSA4, complete sequence	17317-17348	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_AP017660	Sphingobium cloacae strain JCM 10874 plasmid pSCLO_6	49546-49577	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP013073	Sphingobium indicum B90A plasmid pSRL3, complete sequence	31590-31621	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP033968	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed1, complete sequence	152495-152526	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP037902	Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence	185549-185580	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP026546	Cupriavidus metallidurans strain Ni-2 plasmid unnamed2	113248-113279	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP012703	Sphingopyxis macrogoltabida strain EY-1 isolate activated sludge plasmid 3, complete sequence	22889-22920	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	392721-392752	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP005090	Sphingobium sp. TKS plasmid pTK6, complete sequence	26391-26422	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_020544	Sphingomonas sp. MM-1 plasmid pISP3, complete sequence	23963-23994	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP043439	Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence	112491-112522	8	0.75
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	MT108731	Pseudomonas phage Epa43, complete genome	3050-3081	8	0.75
CP025990_32	32.1|4969131|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969131-4969162	32	NZ_CP035502	Sphingosinicella sp. BN140058 plasmid p1, complete sequence	78060-78091	8	0.75
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1044799-1044830	8	0.75
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_CP031081	Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence	147662-147693	8	0.75
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_CP031081	Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence	153426-153457	8	0.75
CP025990_32	32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969192-4969223	32	NZ_CP031083	Paracoccus yeei strain CCUG 32053 plasmid pYEE5, complete sequence	1125-1156	8	0.75
CP025990_32	32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969314-4969345	32	NZ_LR536452	Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 3	194158-194189	8	0.75
CP025990_32	32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969314-4969345	32	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	1331200-1331231	8	0.75
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1487679-1487710	8	0.75
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1200542-1200573	8	0.75
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	399469-399500	8	0.75
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	933622-933653	8	0.75
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1160750-1160781	8	0.75
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	MN096355	Mycobacterium phage Purky, complete genome	4989-5021	8	0.758
CP025990_33	33.5|4974314|33|CP025990|CRISPRCasFinder,CRT	4974314-4974346	33	NZ_CP020927	Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence	188538-188570	8	0.758
CP025990_33	33.5|4974314|33|CP025990|CRISPRCasFinder,CRT	4974314-4974346	33	NZ_CP020927	Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence	53171-53203	8	0.758
CP025990_33	33.7|4974438|33|CP025990|CRISPRCasFinder,CRT	4974438-4974470	33	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	136407-136439	8	0.758
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	518054-518087	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	264629-264662	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	218665-218698	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	518054-518087	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	964356-964389	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	561492-561525	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	23030-23063	8	0.765
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	218206-218239	8	0.765
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	50029-50060	8	0.75
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	50029-50060	8	0.75
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	864677-864708	8	0.75
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	191017-191048	8	0.75
CP025990_35	35.2|4979082|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979082-4979113	32	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	148666-148697	8	0.75
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	57262-57293	8	0.75
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	413877-413908	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	86193-86224	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	924037-924068	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1499214-1499245	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP029453	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509a, complete sequence	327230-327261	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP023069	Ensifer sojae CCBAU 05684 plasmid pSJ05684a, complete sequence	336016-336047	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_000914	Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence	22388-22419	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_000914	Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence	191899-191930	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NC_000914	Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence	374961-374992	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP029233	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436a, complete sequence	285100-285131	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP029233	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436a, complete sequence	343733-343764	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP021357	Rhodococcus sp. S2-17 plasmid pRB11, complete sequence	74117-74148	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP021360	Acidovorax carolinensis strain NA2 plasmid pACNA2.1, complete sequence	29848-29879	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP021367	Acidovorax carolinensis strain P4 plasmid pACP4.1, complete sequence	48299-48330	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP021363	Acidovorax carolinensis strain P3 plasmid pACP3.1, complete sequence	34349-34380	8	0.75
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	MK059749	Mycobacterium phage CRB2, complete genome	6870-6901	8	0.75
CP025990_37	37.1|5319744|34|CP025990|PILER-CR	5319744-5319777	34	NC_023497	Amycolatopsis keratiniphila plasmid pXL100, complete sequence	29687-29720	8	0.765
CP025990_38	38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	5444530-5444565	36	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	106747-106782	8	0.778
CP025990_38	38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	5444530-5444565	36	MN234225	Mycobacterium phage Rhinoforte, complete genome	40775-40810	8	0.778
CP025990_38	38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	5444530-5444565	36	JF712866	Vibrio phage phiVC8, complete genome	10443-10478	8	0.778
CP025990_38	38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	5444530-5444565	36	NZ_AP014801	Rhodovulum sulfidophilum plasmid Plasmid1 DNA, complete genome, strain: DSM 2351	832-867	8	0.778
CP025990_38	38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	5444530-5444565	36	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	19908-19943	8	0.778
CP025990_39	39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574090-5574121	32	NZ_CP016619	Microvirga ossetica strain V5/3m plasmid unnamed2, complete sequence	428129-428160	8	0.75
CP025990_39	39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574090-5574121	32	CP022268	Xanthomonas citri pv. vignicola strain CFBP7112 plasmid plA, complete sequence	27235-27266	8	0.75
CP025990_39	39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574090-5574121	32	CP022268	Xanthomonas citri pv. vignicola strain CFBP7112 plasmid plA, complete sequence	40201-40232	8	0.75
CP025990_39	39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574090-5574121	32	CP022269	Xanthomonas citri pv. vignicola strain CFBP7112 plasmid plB, complete sequence	11422-11453	8	0.75
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	50029-50060	8	0.75
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	50029-50060	8	0.75
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	864677-864708	8	0.75
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	191017-191048	8	0.75
CP025990_39	39.9|5574578|31|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574578-5574608	31	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	88974-89004	8	0.742
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MN317029	Aeromonas phage vB_AhyS-A18P4, complete genome	9640-9672	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	123120-123152	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	206923-206955	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1606193-1606225	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	114239-114271	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	300847-300879	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	700512-700544	8	0.758
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1865578-1865610	8	0.758
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	201247-201279	8	0.758
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	202495-202527	8	0.758
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	196207-196239	8	0.758
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	197455-197487	8	0.758
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	925088-925120	8	0.758
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_CP024940	Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence	1130642-1130674	8	0.758
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP021083	Deinococcus ficus strain CC-FR2-10 plasmid pDFI2, complete sequence	120785-120818	8	0.765
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	KU310943	Pseudomonas phage YMC11/07/P54_PAE_BP, complete genome	3895-3928	8	0.765
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP029174	Methylobacterium sp. DM1 plasmid pLVM1, complete sequence	74052-74083	8	0.75
CP025990_43	43.5|6196115|33|CP025990|CRISPRCasFinder,CRT	6196115-6196147	33	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	28073-28105	8	0.758
CP025990_43	43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6196359-6196391	33	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	2354165-2354197	8	0.758
CP025990_43	43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6196359-6196391	33	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	350264-350296	8	0.758
CP025990_43	43.10|6196420|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6196420-6196452	33	NC_015851	Acidithiobacillus caldus SM-1 megaplasmid, complete sequence	65482-65514	8	0.758
CP025990_44	44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577596-6577628	33	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	1506373-1506405	8	0.758
CP025990_44	44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577596-6577628	33	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	138038-138070	8	0.758
CP025990_47	47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791494-6791527	34	NZ_CP010727	Phaeobacter inhibens strain P88 plasmid pP88_b, complete sequence	81824-81857	8	0.765
CP025990_47	47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791494-6791527	34	NZ_CP010611	Phaeobacter inhibens strain P92 plasmid pP92_a, complete sequence	51439-51472	8	0.765
CP025990_47	47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791494-6791527	34	NZ_CP010716	Phaeobacter piscinae strain P18 plasmid pP18_a, complete sequence	51439-51472	8	0.765
CP025990_47	47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791494-6791527	34	NZ_CP010662	Phaeobacter inhibens strain P74 plasmid pP74_a, complete sequence	51439-51472	8	0.765
CP025990_47	47.22|6791643|38|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791643-6791680	38	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	561321-561358	8	0.789
CP025990_47	47.22|6791643|38|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791643-6791680	38	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	485893-485930	8	0.789
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1592544-1592575	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1393383-1393414	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1344733-1344764	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1592670-1592701	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1344710-1344741	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1088751-1088782	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	754155-754186	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1344740-1344771	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1592210-1592241	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1592152-1592183	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1326874-1326905	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1270641-1270672	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1079758-1079789	8	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1216691-1216722	8	0.75
CP025990_1	1.3|123743|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123743-123775	33	NZ_JX627580	Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence	43900-43932	9	0.727
CP025990_1	1.3|123743|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	123743-123775	33	NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	6806-6838	9	0.727
CP025990_4	4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207496-207528	33	NC_007353	Sphingomonas sp. A1 plasmid pA1 DNA, complete sequence	45388-45420	9	0.727
CP025990_4	4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207496-207528	33	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	468126-468158	9	0.727
CP025990_4	4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207496-207528	33	NZ_MN366361	Bacterium plasmid pALTS33, complete sequence	14070-14102	9	0.727
CP025990_4	4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207496-207528	33	NC_019369	Burkholderia cepacia plasmid pYS1, complete sequence	14094-14126	9	0.727
CP025990_4	4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207618-207651	34	NZ_CP021360	Acidovorax carolinensis strain NA2 plasmid pACNA2.1, complete sequence	46918-46951	9	0.735
CP025990_4	4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207618-207651	34	NZ_CP021367	Acidovorax carolinensis strain P4 plasmid pACP4.1, complete sequence	31176-31209	9	0.735
CP025990_4	4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207618-207651	34	NZ_CP021363	Acidovorax carolinensis strain P3 plasmid pACP3.1, complete sequence	17227-17260	9	0.735
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	MN234206	Arthrobacter phage Racecar, complete genome	12762-12794	9	0.727
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	MN234211	Arthrobacter phage Mimi, complete genome	12763-12795	9	0.727
CP025990_4	4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207741-207774	34	NZ_CP021360	Acidovorax carolinensis strain NA2 plasmid pACNA2.1, complete sequence	46918-46951	9	0.735
CP025990_4	4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207741-207774	34	NZ_CP021367	Acidovorax carolinensis strain P4 plasmid pACP4.1, complete sequence	31176-31209	9	0.735
CP025990_4	4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207741-207774	34	NZ_CP021363	Acidovorax carolinensis strain P3 plasmid pACP3.1, complete sequence	17227-17260	9	0.735
CP025990_4	4.8|207864|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207864-207896	33	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	90619-90651	9	0.727
CP025990_4	4.8|207864|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207864-207896	33	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	90287-90319	9	0.727
CP025990_4	4.9|207925|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207925-207958	34	NZ_CP053858	Rhizobium pusense strain 76 plasmid pR76, complete sequence	42701-42734	9	0.735
CP025990_4	4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	208109-208141	33	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	432024-432056	9	0.727
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	33518-33552	9	0.743
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	MH727545	Mycobacterium phage DismalStressor, complete genome	47342-47376	9	0.743
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NC_026598	Mycobacterium phage Milly, complete genome	47315-47349	9	0.743
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	KX688047	Mycobacterium phage Marcoliusprime, complete genome	47342-47376	9	0.743
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	MF140408	Mycobacterium phage DismalFunk, complete genome	47342-47376	9	0.743
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	MF140411	Mycobacterium phage Findley, complete genome	47339-47373	9	0.743
CP025990_6	6.12|408965|35|CP025990|CRISPRCasFinder,CRT	408965-408999	35	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	6100-6134	9	0.743
CP025990_6	6.12|408965|35|CP025990|CRISPRCasFinder,CRT	408965-408999	35	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	6100-6134	9	0.743
CP025990_6	6.12|408965|35|CP025990|CRISPRCasFinder,CRT	408965-408999	35	NC_010847	Paracoccus aminophilus strain JCM 7686 plasmid pAMI2, complete sequence	12108-12142	9	0.743
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1201012-1201043	9	0.719
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP009453	Sphingopyxis sp. 113P3 plasmid unnamed, complete sequence	20544-20575	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP021029	Rhizobium sp. TAL182 plasmid pRetTAL182e, complete sequence	312791-312822	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013600	Rhizobium sp. N741 plasmid pRspN741e, complete sequence	464618-464649	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013504	Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence	464618-464649	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013510	Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence	463059-463090	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013521	Rhizobium sp. N113 plasmid pRspN113d, complete sequence	467306-467337	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013494	Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence	461425-461456	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013515	Rhizobium sp. N1314 plasmid pRspN1314d, complete sequence	308105-308136	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013594	Rhizobium sp. N871 plasmid pRspN871d, complete sequence	464618-464649	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP013605	Rhizobium sp. N731 plasmid pRspN731d, complete sequence	308099-308130	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP019608	Tessaracoccus flavescens strain SST-39T plasmid unnamed, complete sequence	39633-39664	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP006990	Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence	543276-543307	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	452227-452258	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	526804-526835	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NZ_CP050095	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b1, complete sequence	159509-159540	9	0.719
CP025990_8	8.3|478807|32|CP025990|CRISPRCasFinder	478807-478838	32	NC_008381	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence	369776-369807	9	0.719
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1178718-1178749	9	0.719
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	780443-780474	9	0.719
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	437704-437735	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	709566-709597	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	439723-439754	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP046575	Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence	3533-3564	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP049358	Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence	318696-318727	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP011044	Clavibacter michiganensis subsp. insidiosus strain R1-1 plasmid pCI1, complete sequence	35822-35853	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP021035	Clavibacter michiganensis subsp. insidiosus strain R1-3 plasmid pCI1, complete sequence	35822-35853	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP021039	Clavibacter michiganensis subsp. insidiosus strain ATCC 10253 plasmid pCI1, complete sequence	36900-36931	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	27898-27929	9	0.719
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP031159	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence	299420-299451	9	0.719
CP025990_8	8.7|478685|33|CP025990|PILER-CR,CRT	478685-478717	33	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	1154494-1154526	9	0.727
CP025990_8	8.7|478685|33|CP025990|PILER-CR,CRT	478685-478717	33	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1201012-1201044	9	0.727
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	203319-203351	9	0.727
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NC_012854	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence	180398-180430	9	0.727
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP019608	Tessaracoccus flavescens strain SST-39T plasmid unnamed, complete sequence	39633-39665	9	0.727
CP025990_9	9.16|482147|32|CP025990|CRT	482147-482178	32	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	580239-580270	9	0.719
CP025990_10	10.1|554801|33|CP025990|CRT	554801-554833	33	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	378652-378684	9	0.727
CP025990_10	10.1|554801|33|CP025990|CRT	554801-554833	33	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	382007-382039	9	0.727
CP025990_10	10.1|554801|33|CP025990|CRT	554801-554833	33	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	494927-494959	9	0.727
CP025990_10	10.1|554801|33|CP025990|CRT	554801-554833	33	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1137582-1137614	9	0.727
CP025990_10	10.1|554801|33|CP025990|CRT	554801-554833	33	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	141048-141080	9	0.727
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	231744-231777	9	0.735
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	302551-302584	9	0.735
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	LN997844	Streptomyces reticuli genome assembly TUE45, plasmid : III	71051-71084	9	0.735
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	LN997844	Streptomyces reticuli genome assembly TUE45, plasmid : III	71435-71468	9	0.735
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	LN997844	Streptomyces reticuli genome assembly TUE45, plasmid : III	71531-71564	9	0.735
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	LN997844	Streptomyces reticuli genome assembly TUE45, plasmid : III	71627-71660	9	0.735
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	LN997844	Streptomyces reticuli genome assembly TUE45, plasmid : III	71723-71756	9	0.735
CP025990_10	10.9|555291|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	555291-555323	33	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	41646-41678	9	0.727
CP025990_13	13.4|792104|35|CP025990|PILER-CR,CRT	792104-792138	35	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	264004-264038	9	0.743
CP025990_13	13.17|792105|34|CP025990|CRISPRCasFinder	792105-792138	34	NZ_LR134457	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 15, complete sequence	6658-6691	9	0.735
CP025990_13	13.17|792105|34|CP025990|CRISPRCasFinder	792105-792138	34	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	166812-166845	9	0.735
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	NZ_CP020040	Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence	214920-214954	9	0.743
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	MT723937	Gordonia phage JKSyngboy, complete genome	17638-17672	9	0.743
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	MH450129	Gordonia phage Ribeye, complete genome	18200-18234	9	0.743
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	MH976509	Gordonia phage Bizzy, complete genome	17173-17207	9	0.743
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	MH651168	Gordonia phage Ashertheman, complete genome	17272-17306	9	0.743
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	MH976513	Gordonia phage Kroos, complete genome	17737-17771	9	0.743
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	MK967396	Gordonia phage Tangerine, complete genome	16865-16899	9	0.743
CP025990_14	14.2|1142214|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142214-1142249	36	MH271303	Microbacterium phage MementoMori, complete genome	16116-16151	9	0.75
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	254326-254361	9	0.75
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	217316-217351	9	0.75
CP025990_18	18.2|2981929|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981929-2981960	32	NZ_CP016620	Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence	453471-453502	9	0.719
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_CP009975	Pseudomonas putida S12 plasmid pTTS12, complete sequence	514417-514448	9	0.719
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	88407-88438	9	0.719
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	NC_007762	Rhizobium etli CFN 42 plasmid p42a, complete sequence	109981-110012	9	0.719
CP025990_19	19.4|3490862|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	3490862-3490896	35	NZ_CP034352	Streptomyces sp. W1SF4 plasmid p2, complete sequence	230631-230665	9	0.743
CP025990_19	19.4|3490862|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	3490862-3490896	35	NC_011366	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence	442988-443022	9	0.743
CP025990_22	22.9|3492088|34|CP025990|CRT	3492088-3492121	34	MG065691	UNVERIFIED: Campylobacter phage A11a, complete genome	1356-1389	9	0.735
CP025990_22	22.9|3492088|34|CP025990|CRT	3492088-3492121	34	MG065686	UNVERIFIED: Campylobacter phage A18a, complete genome	172734-172767	9	0.735
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	73185-73217	9	0.727
CP025990_22	22.13|3492357|33|CP025990|CRT	3492357-3492389	33	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	78256-78288	9	0.727
CP025990_22	22.14|3492423|31|CP025990|CRT	3492423-3492453	31	NZ_CP013917	Sphingomonas sp. LK11 plasmid unnamed2, complete sequence	90305-90335	9	0.71
CP025990_24	24.2|3572256|32|CP025990|PILER-CR	3572256-3572287	32	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	447626-447657	9	0.719
CP025990_24	24.4|3572378|32|CP025990|PILER-CR	3572378-3572409	32	CP052219	Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-2, complete sequence	64691-64722	9	0.719
CP025990_24	24.4|3572378|32|CP025990|PILER-CR	3572378-3572409	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3066737-3066768	9	0.719
CP025990_24	24.4|3572378|32|CP025990|PILER-CR	3572378-3572409	32	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1276086-1276117	9	0.719
CP025990_24	24.4|3572378|32|CP025990|PILER-CR	3572378-3572409	32	NZ_CP024642	Klebsiella michiganensis strain F107 plasmid unnamed2, complete sequence	123025-123056	9	0.719
CP025990_24	24.5|3572196|31|CP025990|CRISPRCasFinder	3572196-3572226	31	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	14285-14315	9	0.71
CP025990_24	24.8|3572379|31|CP025990|CRISPRCasFinder	3572379-3572409	31	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1276086-1276116	9	0.71
CP025990_25	25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT	3609657-3609687	31	NC_047861	Bordetella phage vB_BbrM_PHB04, complete genome	93953-93983	9	0.71
CP025990_27	27.1|3802758|33|CP025990|CRISPRCasFinder	3802758-3802790	33	NZ_CP033968	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed1, complete sequence	279692-279724	9	0.727
CP025990_27	27.1|3802758|33|CP025990|CRISPRCasFinder	3802758-3802790	33	NZ_CP043439	Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence	275751-275783	9	0.727
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_KY494864	Pseudomonas aeruginosa strain FFUP_PS_37 plasmid pJB37, complete sequence	343138-343168	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_KU130294	Pseudomonas putida strain 12969 plasmid p12969-DIM, complete sequence	315824-315854	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP009975	Pseudomonas putida S12 plasmid pTTS12, complete sequence	453402-453432	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP039989	Pseudomonas aeruginosa strain T2436 plasmid pBT2436, complete sequence	302432-302462	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP039991	Pseudomonas aeruginosa strain T2101 plasmid pBT2101, complete sequence	334853-334883	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	278908-278938	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_MN433457	Pseudomonas aeruginosa strain PAB546 plasmid pNK546-KPC, complete sequence	424861-424891	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP045003	Pseudomonas aeruginosa strain PAG5 plasmid pPAG5, complete sequence	201612-201642	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP045917	Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence	290085-290115	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF344571	Pseudomonas aeruginosa plasmid pR31014-IMP, complete sequence	319728-319758	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF344568	Pseudomonas aeruginosa plasmid p727-IMP, complete sequence	315498-315528	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF344569	Pseudomonas aeruginosa plasmid p12939-PER, complete sequence	386526-386556	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	MF344570	Pseudomonas aeruginosa plasmid pA681-IMP, complete sequence	327550-327580	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	264945-264975	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP040126	Pseudomonas aeruginosa strain PA298 plasmid pBM908, complete sequence	342035-342065	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_CP016215	Pseudomonas aeruginosa strain PA121617 plasmid pBM413, complete sequence	415922-415952	9	0.71
CP025990_28	28.1|4214437|31|CP025990|CRISPRCasFinder,CRT	4214437-4214467	31	NZ_KY883660	Pseudomonas putida strain SY153 plasmid pSY153-MDR, complete sequence	355728-355758	9	0.71
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	944221-944252	9	0.719
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MG018928	Pseudomonas phage inbricus, complete genome	42778-42810	9	0.727
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MK962632	Achromobacter phage vB_AxyP_19-32_Axy13, complete genome	58576-58608	9	0.727
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MK962641	Achromobacter phage vB_AxyP_19-32_Axy24, complete genome	61099-61131	9	0.727
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MK962626	Achromobacter phage vB_AxyP_19-32_Axy04, complete genome	60221-60253	9	0.727
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MK867354	Synechococcus phage S-SCSM1, complete genome	107421-107453	9	0.727
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MK962631	Achromobacter phage vB_AxyP_19-32_Axy12, complete genome	61172-61204	9	0.727
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	KT321317	Achromobacter phage phiAxp-3, complete genome	59747-59779	9	0.727
CP025990_30	30.1|4939798|34|CP025990|CRISPRCasFinder,CRT	4939798-4939831	34	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1709290-1709323	9	0.735
CP025990_30	30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939927-4939961	35	NZ_CP020441	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence	232906-232940	9	0.743
CP025990_30	30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939927-4939961	35	NZ_CP020447	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed7, complete sequence	46952-46986	9	0.743
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	695546-695577	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	583655-583686	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	384022-384053	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	27219-27250	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP039924	Agrobacterium tumefaciens strain CFBP7129 plasmid pAtCFBP7129a, complete sequence	51959-51990	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	939878-939909	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	142515-142546	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	427127-427158	9	0.719
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP023065	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence	518769-518800	9	0.719
CP025990_32	32.1|4969131|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969131-4969162	32	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	675445-675476	9	0.719
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	JX100810	Caulobacter phage CcrColossus, complete genome	40182-40213	9	0.719
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NZ_CP020385	Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence	80055-80086	9	0.719
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	307651-307683	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	765657-765689	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NC_015409	Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence	15757-15789	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	LT999987	Pseudomonas phage vB_PaeS_PAO1_HW12 genome assembly, complete genome: monopartite	20150-20182	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	KM389460	UNVERIFIED: Pseudomonas phage F_MX560sp/Pa1651 clone contig00001 genomic sequence	18325-18357	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	EU744250	Mycobacterium virus Pukovnik, complete genome	19174-19206	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	KM389278	UNVERIFIED: Pseudomonas phage Phi05_1400 B clone contig00006 genomic sequence	11372-11404	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NC_031279	Mycobacterium phage Bactobuster, complete genome	19268-19300	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	KJ477077	Pseudomonas phage JD024, complete genome	19037-19069	9	0.727
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	JX434030	Pseudomonas phage JBD5, complete genome	20493-20525	9	0.727
CP025990_33	33.4|4974253|33|CP025990|CRISPRCasFinder,CRT	4974253-4974285	33	NZ_CP010024	Paraburkholderia fungorum strain ATCC BAA-463 plasmid pBIL, complete sequence	388519-388551	9	0.727
CP025990_33	33.7|4974438|33|CP025990|CRISPRCasFinder,CRT	4974438-4974470	33	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	652334-652366	9	0.727
CP025990_33	33.7|4974438|33|CP025990|CRISPRCasFinder,CRT	4974438-4974470	33	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	405402-405434	9	0.727
CP025990_33	33.7|4974438|33|CP025990|CRISPRCasFinder,CRT	4974438-4974470	33	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	322792-322824	9	0.727
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP019604	Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence	214255-214288	9	0.735
CP025990_34	34.1|4978725|34|CP025990|CRISPRCasFinder	4978725-4978758	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1429372-1429405	9	0.735
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	35344-35375	9	0.719
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	107443-107474	9	0.719
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	846745-846776	9	0.719
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1917652-1917683	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	469730-469761	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP041605	Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence	91539-91570	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP048642	Streptomyces aureoverticillatus strain HN6 plasmid unnamed, complete sequence	111574-111605	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP042825	Rhizobium sp. WL3 plasmid unnamed2, complete sequence	293218-293249	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	78769-78800	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	749968-749999	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_LT703506	Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 2	153202-153233	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	85911-85942	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP046510	Erwinia sp. J780 plasmid pla1, complete sequence	4039-4070	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP039644	Azospirillum sp. TSA2s plasmid p2, complete sequence	101079-101110	9	0.719
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	MN617843	Mycobacterium phage Quesadilla, complete genome	6870-6901	9	0.719
CP025990_36	36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	5001328-5001361	34	NZ_CP045411	Roseovarius sp. THAF8 plasmid pTHAF8_a, complete sequence	145531-145564	9	0.735
CP025990_36	36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	5001328-5001361	34	NZ_CP045394	Roseovarius sp. THAF27 plasmid pTHAF27_a, complete sequence	146818-146851	9	0.735
CP025990_36	36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	5001328-5001361	34	NZ_CP045405	Roseovarius sp. THAF9 plasmid pTHAF9_a, complete sequence	141221-141254	9	0.735
CP025990_36	36.5|5001390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5001390-5001422	33	MK249149	Blackfly microvirus SF02 isolate 045, complete genome	2953-2985	9	0.727
CP025990_36	36.6|5001451|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5001451-5001483	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1403271-1403303	9	0.727
CP025990_38	38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT	5444530-5444565	36	NZ_CP030863	Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence	102841-102876	9	0.75
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	35344-35375	9	0.719
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	107443-107474	9	0.719
CP025990_40	40.2|5592159|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5592159-5592191	33	NZ_CP021004	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pE, complete sequence	23723-23755	9	0.727
CP025990_40	40.2|5592159|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5592159-5592191	33	KC170285	Uncultured bacterium plasmid pMBUI2, complete sequence	37061-37093	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1650698-1650730	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1515789-1515821	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	AP017627	Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome	42705-42737	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1137534-1137566	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1535772-1535804	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	969521-969553	9	0.727
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1444028-1444060	9	0.727
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	942734-942766	9	0.727
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1061075-1061107	9	0.727
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	31326-31358	9	0.727
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	81755-81787	9	0.727
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	454092-454124	9	0.727
CP025990_41	41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593974-5594006	33	NZ_CP012183	Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence	48464-48496	9	0.727
CP025990_41	41.6|5594035|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5594035-5594067	33	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	245230-245262	9	0.727
CP025990_41	41.11|5594341|33|CP025990|CRISPRCasFinder,CRT	5594341-5594373	33	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	41296-41328	9	0.727
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP024426	Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence	101536-101569	9	0.735
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP020445	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence	41357-41390	9	0.735
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	55207-55240	9	0.735
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	366139-366172	9	0.735
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	842057-842090	9	0.735
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	325545-325578	9	0.735
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	CP003180	Sulfobacillus acidophilus DSM 10332 plasmid, complete sequence	47996-48027	9	0.719
CP025990_43	43.6|6196176|33|CP025990|CRISPRCasFinder,CRT	6196176-6196208	33	NZ_CP040453	Halomonas sp. PA16-9 plasmid p_unnamed2, complete sequence	48734-48766	9	0.727
CP025990_47	47.27|6792007|36|CP025990|CRT,PILER-CR,CRISPRCasFinder	6792007-6792042	36	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	145310-145345	9	0.75
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP053710	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence	66436-66467	9	0.719
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	MF766045	Streptomyces phage Daudau, complete genome	5392-5425	10	0.706
CP025990_4	4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207618-207651	34	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	72021-72054	10	0.706
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1473048-1473080	10	0.697
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	NZ_CP022318	Brachybacterium avium strain VR2415 plasmid unnamed2, complete sequence	8994-9026	10	0.697
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1473055-1473087	10	0.697
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1383966-1383998	10	0.697
CP025990_4	4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder	207680-207712	33	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1329255-1329287	10	0.697
CP025990_4	4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	207741-207774	34	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	72021-72054	10	0.706
CP025990_6	6.1|408245|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408245-408279	35	NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	175919-175953	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	472065-472099	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	460256-460290	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	420553-420587	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	426964-426998	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NC_016591	Burkholderia sp. YI23 plasmid byi_2p, complete sequence	15683-15717	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	CP000617	Burkholderia vietnamiensis G4 plasmid pBVIE01, complete sequence	195277-195311	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	472099-472133	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	472098-472132	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	472090-472124	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	444497-444531	10	0.714
CP025990_6	6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	408571-408605	35	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	444487-444521	10	0.714
CP025990_8	8.1|478685|32|CP025990|CRISPRCasFinder	478685-478716	32	NZ_CP025513	Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence	431504-431535	10	0.688
CP025990_8	8.5|478929|32|CP025990|CRISPRCasFinder	478929-478960	32	NZ_CP045120	Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence	14167-14198	10	0.688
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	238687-238718	10	0.688
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	226713-226744	10	0.688
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_012520	Rhodococcus opacus B4 plasmid pROB01, complete sequence	335089-335120	10	0.688
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	CP054917	Streptomyces sp. NA02950 plasmid unnamed, complete sequence	48176-48207	10	0.688
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	303965-303996	10	0.688
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NZ_CP006990	Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence	543276-543308	10	0.697
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	452226-452258	10	0.697
CP025990_8	8.9|478807|33|CP025990|PILER-CR,CRT	478807-478839	33	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	526804-526836	10	0.697
CP025990_9	9.9|481683|35|CP025990|CRT	481683-481717	35	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	947490-947524	10	0.714
CP025990_9	9.9|481683|35|CP025990|CRT	481683-481717	35	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	99727-99761	10	0.714
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NC_023282	Streptomyces sp. FR1 plasmid pFRL2, complete sequence	70324-70357	10	0.706
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	JN106175	Uncultured bacterium plasmid pAKD34, complete sequence	83367-83400	10	0.706
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	89719-89752	10	0.706
CP025990_11	11.1|711686|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	711686-711719	34	CP053333	Salmonella enterica subsp. diarizonae serovar 47:k:z35 strain 2009K1094 plasmid unnamed1, complete sequence	45603-45636	10	0.706
CP025990_11	11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711809-711841	33	MH454080	Paenibacillus phage Ley, complete genome	32519-32551	10	0.697
CP025990_11	11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711809-711841	33	MH454076	Paenibacillus phage Ash, complete genome	32519-32551	10	0.697
CP025990_11	11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711809-711841	33	MH431938	Paenibacillus phage C7Cdelta, complete genome	32470-32502	10	0.697
CP025990_11	11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	711809-711841	33	KT755656	Paenibacillus phage Tripp, complete genome	33458-33490	10	0.697
CP025990_14	14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142149-1142183	35	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	464106-464140	10	0.714
CP025990_14	14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142478-1142512	35	KY365739	Streptomyces phage BabyGotBac, complete genome	20683-20717	10	0.714
CP025990_14	14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142478-1142512	35	MH178382	Streptomyces phage Salete, complete genome	20683-20717	10	0.714
CP025990_14	14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142478-1142512	35	KU189325	Streptomyces phage Maih, complete genome	20682-20716	10	0.714
CP025990_14	14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142478-1142512	35	MH178381	Streptomyces phage BayC, complete genome	20683-20717	10	0.714
CP025990_14	14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142478-1142512	35	NC_047756	Caulobacter phage Sansa, complete genome	45723-45757	10	0.714
CP025990_14	14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT	1142478-1142512	35	KP876466	Streptomyces phage TP1604, complete genome	20683-20717	10	0.714
CP025990_14	14.10|1142741|36|CP025990|CRISPRCasFinder,CRT	1142741-1142776	36	NZ_CP045120	Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence	113958-113993	10	0.722
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	NC_010811	Ralstonia phage RSL1, complete genome	18051-18082	10	0.688
CP025990_18	18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	2981990-2982021	32	AB366653	Ralstonia phage RSL1 DNA, complete genome	18051-18082	10	0.688
CP025990_24	24.1|3572195|32|CP025990|PILER-CR	3572195-3572226	32	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	14285-14316	10	0.688
CP025990_26	26.1|3610301|33|CP025990|CRT	3610301-3610333	33	NZ_CP049358	Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence	252444-252476	10	0.697
CP025990_26	26.1|3610301|33|CP025990|CRT	3610301-3610333	33	NZ_CP031159	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence	226640-226672	10	0.697
CP025990_26	26.1|3610301|33|CP025990|CRT	3610301-3610333	33	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	525486-525518	10	0.697
CP025990_26	26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder	3610423-3610456	34	NC_009470	Acidiphilium cryptum JF-5 plasmid pACRY04, complete sequence	28324-28357	10	0.706
CP025990_26	26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder	3610423-3610456	34	NC_015188	Acidiphilium multivorum AIU301 plasmid pACMV4, complete sequence	153-186	10	0.706
CP025990_26	26.11|3610485|33|CP025990|PILER-CR,CRISPRCasFinder	3610485-3610517	33	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	89594-89626	10	0.697
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	285929-285960	10	0.688
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	761291-761322	10	0.688
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5488237-5488268	10	0.688
CP025990_29	29.5|4677597|33|CP025990|CRISPRCasFinder,CRT	4677597-4677629	33	MN694715	Marine virus AFVG_250M935, complete genome	39109-39141	10	0.697
CP025990_30	30.1|4939798|34|CP025990|CRISPRCasFinder,CRT	4939798-4939831	34	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	2145387-2145420	10	0.706
CP025990_30	30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939927-4939961	35	NZ_CP020040	Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence	291282-291316	10	0.714
CP025990_31	31.2|4968703|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4968703-4968734	32	NC_014563	Pantoea vagans C9-1 plasmid pPag2, complete sequence	123737-123768	10	0.688
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1448844-1448875	10	0.688
CP025990_31	31.4|4968825|32|CP025990|CRISPRCasFinder,CRT	4968825-4968856	32	NZ_CP027239	Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence	78846-78877	10	0.688
CP025990_32	32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969314-4969345	32	MF459647	Erwinia phage vB_EamM_Joad, complete genome	152646-152677	10	0.688
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NZ_CP035092	Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence	597053-597084	10	0.688
CP025990_32	32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969375-4969406	32	NC_008688	Paracoccus denitrificans PD1222 plasmid 1, complete sequence	190586-190617	10	0.688
CP025990_32	32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969436-4969467	32	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	168985-169016	10	0.688
CP025990_32	32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969436-4969467	32	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	217024-217055	10	0.688
CP025990_32	32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	4969436-4969467	32	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	321119-321150	10	0.688
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	49504-49536	10	0.697
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	MH426726	Erwinia phage Pavtok, complete genome	47526-47558	10	0.697
CP025990_33	33.3|4974192|33|CP025990|CRISPRCasFinder,CRT	4974192-4974224	33	NC_028849	Mycobacterium phage Luchador, complete genome	17885-17917	10	0.697
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	265304-265335	10	0.688
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_LR134469	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence	111735-111766	10	0.688
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	961665-961696	10	0.688
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_CP036516	Lichenihabitans psoromatis strain PAMC 29148 plasmid p_unnamed1, complete sequence	68775-68806	10	0.688
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	NZ_CP031599	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence	144754-144785	10	0.688
CP025990_35	35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979143-4979174	32	MH229864	Streptomyces phage UNTPL, complete genome	44611-44642	10	0.688
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	2397-2428	10	0.688
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP016618	Microvirga ossetica strain V5/3m plasmid unnamed3, complete sequence	616505-616536	10	0.688
CP025990_37	37.1|5319744|34|CP025990|PILER-CR	5319744-5319777	34	NC_008441	Streptomyces laurentii plasmid pSLS DNA, complete sequence	1957-1990	10	0.706
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	265304-265335	10	0.688
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_LR134469	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence	111735-111766	10	0.688
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	961665-961696	10	0.688
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_CP036516	Lichenihabitans psoromatis strain PAMC 29148 plasmid p_unnamed1, complete sequence	68775-68806	10	0.688
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MN871452	UNVERIFIED: Serratia phage KpZh_1, complete genome	256663-256695	10	0.697
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MN871447	UNVERIFIED: Serratia phage KpLz_1_41, complete genome	204268-204300	10	0.697
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MN871453	UNVERIFIED: Serratia phage KpZh_LPS_45, complete genome	124334-124366	10	0.697
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MN871451	UNVERIFIED: Serratia phage KpYy_2_45, complete genome	103262-103294	10	0.697
CP025990_41	41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593852-5593884	33	MN871448	UNVERIFIED: Serratia phage KpSz_1, complete genome	104309-104341	10	0.697
CP025990_41	41.13|5594462|34|CP025990|CRISPRCasFinder,CRT	5594462-5594495	34	NZ_CP029174	Methylobacterium sp. DM1 plasmid pLVM1, complete sequence	74050-74083	10	0.706
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	842059-842090	10	0.688
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	KX576640	Arthrobacter phage RcigaStruga, complete genome	3940-3971	10	0.688
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	MG210949	Arthrobacter phage Huntingdon, complete genome	3940-3971	10	0.688
CP025990_41	41.15|5594462|32|CP025990|PILER-CR	5594462-5594493	32	EF579802	Microbacterium phage Min1, complete genome	46093-46124	10	0.688
CP025990_42	42.2|5600635|33|CP025990|CRISPRCasFinder,CRT	5600635-5600667	33	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	182799-182831	10	0.697
CP025990_43	43.3|6195993|33|CP025990|CRISPRCasFinder,CRT	6195993-6196025	33	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	173429-173461	10	0.697
CP025990_43	43.5|6196115|33|CP025990|CRISPRCasFinder,CRT	6196115-6196147	33	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	238959-238991	10	0.697
CP025990_43	43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6196359-6196391	33	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	103425-103457	10	0.697
CP025990_44	44.4|6577474|33|CP025990|CRISPRCasFinder,CRT,PILER-CR	6577474-6577506	33	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	1110157-1110189	10	0.697
CP025990_47	47.23|6791718|35|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791718-6791752	35	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	12305-12339	10	0.714
CP025990_47	47.27|6792007|36|CP025990|CRT,PILER-CR,CRISPRCasFinder	6792007-6792042	36	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	266515-266550	10	0.722
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP012659	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence	2820-2851	10	0.688
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP012659	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence	38842-38873	10	0.688
CP025990_48	48.1|6810224|32|CP025990|CRISPRCasFinder	6810224-6810255	32	NZ_CP029972	Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence	10287-10318	10	0.688
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	351158-351191	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	350101-350134	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	1587623-1587656	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	346187-346220	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	345343-345376	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	964251-964284	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	691992-692025	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	595910-595943	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	227473-227506	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1134137-1134170	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	497223-497256	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	349223-349256	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1390421-1390454	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1352537-1352570	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	1456644-1456677	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	61116-61149	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	955324-955357	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	1077428-1077461	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	617061-617094	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	669431-669464	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1508755-1508788	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	1285147-1285180	11	0.676
CP025990_3	3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT	135512-135545	34	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1390428-1390461	11	0.676
CP025990_6	6.8|408703|37|CP025990|PILER-CR,CRISPRCasFinder,CRT	408703-408739	37	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1740330-1740366	11	0.703
CP025990_8	8.4|478868|32|CP025990|CRISPRCasFinder	478868-478899	32	MG872834	Gordonia phage Confidence, complete genome	27688-27719	11	0.656
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	1081221-1081252	11	0.656
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_010627	Paraburkholderia phymatum STM815 plasmid pBPHY02, complete sequence	480619-480650	11	0.656
CP025990_8	8.6|478990|32|CP025990|CRISPRCasFinder	478990-479021	32	NC_018696	Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence	676253-676284	11	0.656
CP025990_9	9.16|482147|32|CP025990|CRT	482147-482178	32	NC_007950	Polaromonas sp. JS666 plasmid 2, complete sequence	240788-240819	11	0.656
CP025990_10	10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder	555168-555201	34	NC_015724	Cupriavidus necator N-1 plasmid pBB2, complete sequence	116882-116915	11	0.676
CP025990_13	13.21|792395|37|CP025990|CRISPRCasFinder	792395-792431	37	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	500253-500289	11	0.703
CP025990_18	18.7|2982234|32|CP025990|CRISPRCasFinder,CRT	2982234-2982265	32	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	2452689-2452720	11	0.656
CP025990_19	19.3|3490795|37|CP025990|PILER-CR,CRISPRCasFinder,CRT	3490795-3490831	37	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	491894-491930	11	0.703
CP025990_26	26.2|3610358|37|CP025990|CRT	3610358-3610394	37	NZ_LR134450	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence	274246-274282	11	0.703
CP025990_26	26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder	3610423-3610456	34	NZ_CP039426	Citricoccus sp. SGAir0253 plasmid unnamed2, complete sequence	34640-34673	11	0.676
CP025990_26	26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder	3610423-3610456	34	NZ_CP039431	Citricoccus sp. SGAir0453 plasmid unnamed2, complete sequence	34640-34673	11	0.676
CP025990_28	28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4214497-4214528	32	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1903863-1903894	11	0.656
CP025990_30	30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939927-4939961	35	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	573867-573901	11	0.686
CP025990_35	35.1|4979021|32|CP025990|CRISPRCasFinder,CRT	4979021-4979052	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	591660-591691	11	0.656
CP025990_35	35.2|4979082|32|CP025990|CRISPRCasFinder,CRT,PILER-CR	4979082-4979113	32	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	195676-195707	11	0.656
CP025990_35	35.4|4979204|32|CP025990|CRISPRCasFinder,CRT	4979204-4979235	32	NZ_CP032696	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525b, complete sequence	323130-323161	11	0.656
CP025990_39	39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT	5574151-5574182	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	591660-591691	11	0.656
CP025990_41	41.4|5593913|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593913-5593945	33	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	6447-6479	11	0.667
CP025990_41	41.4|5593913|33|CP025990|PILER-CR,CRISPRCasFinder,CRT	5593913-5593945	33	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	961412-961444	11	0.667
CP025990_47	47.3|6790244|38|CP025990|CRT,PILER-CR,CRISPRCasFinder	6790244-6790281	38	NC_030907	Gordonia phage GMA5, complete genome	2019-2056	11	0.711
CP025990_47	47.24|6791790|35|CP025990|CRT,PILER-CR,CRISPRCasFinder	6791790-6791824	35	NZ_CP013744	Streptomyces sp. CdTB01 plasmid unnamed, complete sequence	175935-175969	11	0.686
CP025990_30	30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939862-4939896	35	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	1147766-1147800	12	0.657
CP025990_30	30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939862-4939896	35	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	895697-895731	12	0.657
CP025990_30	30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939862-4939896	35	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	1147769-1147803	12	0.657
CP025990_30	30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939862-4939896	35	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	694176-694210	12	0.657
CP025990_30	30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939862-4939896	35	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	319234-319268	12	0.657
CP025990_30	30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR	4939862-4939896	35	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	1127736-1127770	12	0.657

1. spacer 28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 2, identity: 0.938

cggtgcgggttggcggtctatcggtgcggcta	CRISPR spacer
cggtgcgggttggcggtctaccggtgcggctc	Protospacer
********************.********** 

2. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 2, identity: 0.938

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
ggctcgcgggtgatcgtcaccggacggctcaa	Protospacer
*********** *********** ********

3. spacer 17.1|2049653|25|CP025990|CRISPRCasFinder matches to NZ_CP023779 (Nocardia terpenica strain NC_YFY_NT001 plasmid p_NC_YFY_NT001, complete sequence) position: , mismatch: 3, identity: 0.88

cgaccggagcgacgcggacggcacc	CRISPR spacer
cgaccggaccgacgaggacggcaac	Protospacer
******** ***** ******** *

4. spacer 17.1|2049653|25|CP025990|CRISPRCasFinder matches to NC_019789 (Deinococcus peraridilitoris DSM 19664 plasmid pDEIPE01, complete sequence) position: , mismatch: 3, identity: 0.88

cgaccggagcgacgcggacggcacc	CRISPR spacer
ccaccggagcgacctggacggcacc	Protospacer
* *********** .**********

5. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_AP018719 (Sterolibacteriaceae bacterium J5B plasmid pSTJ1, complete sequence) position: , mismatch: 3, identity: 0.889

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cagcagcagcaacagtccggccagcaa	Protospacer
* ************** *********.

6. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP020927 (Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
gatcggcgtcgactgcgaccaggttg	Protospacer
 .****** ******** ********

7. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP020927 (Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
gatcggcgtcgactgcgaccaggttg	Protospacer
 .****** ******** ********

8. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
tgttggcgacgactgcgcccagagcg	Protospacer
***.******************. .*

9. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP030128 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
ggtcggcgtcgactgcgcccaggcag	Protospacer
 ******* **************. *

10. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_AP017657 (Sphingobium cloacae strain JCM 10874 plasmid pSCLO_3, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
tgtcggcaacgtctgcgcccaggcag	Protospacer
*******.*** ***********. *

11. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP005191 (Sphingobium sp. MI1205 plasmid pMI2, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
tgtcggcaacgtctgcgcccaggcag	Protospacer
*******.*** ***********. *

12. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP011274 (Planctomyces sp. SH-PL62 plasmid pPL62-1, complete sequence) position: , mismatch: 4, identity: 0.846

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
cgtcggcgacgacggcccccaggtcg	Protospacer
.************ ** *******.*

13. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP046321 (Gordonia bronchialis strain FDAARGOS_676 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.875

gcccgtgc-cggtggcggtgtggccggtgtggt	CRISPR spacer
-cccctgcaaggtggcggtgtggccggtggggt	Protospacer
 *** ***  ******************* ***

14. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_013442 (Gordonia bronchialis DSM 43247 plasmid pGBRO01, complete sequence) position: , mismatch: 4, identity: 0.875

gcccgtgc-cggtggcggtgtggccggtgtggt	CRISPR spacer
-cccctgcaaggtggcggtgtggccggtggggt	Protospacer
 *** ***  ******************* ***

15. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cggcagcagcaacaacacggccagcat	Protospacer
* ************..********** 

16. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP054603 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cgccagcagcatcagtgcggccagcag	Protospacer
*  ******** ****.**********

17. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cggcagcagcaacagcaccgccagcat	Protospacer
* *************.** ******* 

18. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cggcagcagcaacagcaccgccagcat	Protospacer
* *************.** ******* 

19. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cggcagcagcaacagcaccgccagcat	Protospacer
* *************.** ******* 

20. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cggcagcagcaacagcaccgccagcat	Protospacer
* *************.** ******* 

21. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NC_010815 (Geobacter lovleyi SZ plasmid pGLOV01, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cagcttcagcaactgtacggccagcag	Protospacer
* **  ******* *************

22. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046332 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2) position: , mismatch: 5, identity: 0.857

cgctcggcgcgcaccgcggcgagctcggcgcgcag-	CRISPR spacer
cgctcggcgcgcaccgcgtcgcgct-ggtgcgcggt	Protospacer
****************** ** *** **.****.* 

23. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_006466 (Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence) position: , mismatch: 5, identity: 0.857

cgctcggcgcgcaccgcggcgagctcggcgcgcag-	CRISPR spacer
cgctcggcgcgcaccgcgtcgcgct-ggtgcgcggt	Protospacer
****************** ** *** **.****.* 

24. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP038146 (Streptomyces sp. S501 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

gcgccccgg-acgcggacgtcctcgaactcctg	CRISPR spacer
-agccgcggtacgcggacgtcctggacctcctg	Protospacer
  *** *** ************* ** ******

25. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_021347 (Rhodococcus phage E3, complete genome) position: , mismatch: 5, identity: 0.839

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
ggaagcgcctcgaggccgagcgtgtcggcaa	Protospacer
*  * ** ********************* *

26. spacer 28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007516 (Rubrobacter radiotolerans strain RSPS-4 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.844

-tgcgccgggtcggggaccacgtccacgtcgcc	CRISPR spacer
atgcgtc-ggtcggggacatcgtccacgtcgcg	Protospacer
 ****.* **********  ************ 

27. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015623 (Corynebacterium crudilactis strain JZ16 plasmid pCRULAC1, complete sequence) position: , mismatch: 5, identity: 0.844

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
ggtatgcgcgtcatcgtcaccggtcgcctcaa	Protospacer
**. .*** ***************** *****

28. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.848

ccgcgg-cggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
-tgcggcccgtctgctcgacgaggccgcgcgcac	Protospacer
 .**** * ************  ***********

29. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 5, identity: 0.808

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
cgtcggcgtcgactacgcccaggtgc	Protospacer
.******* *****.*********  

30. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

cggatgtccgcgacggcggcct-cgcgggatgt	CRISPR spacer
cggatgtcagcgacggcgtcctccgcgtgctg-	Protospacer
******** ********* *** **** * ** 

31. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 5, identity: 0.844

gcccgtgc-cggtggcggtgtggccggtgtggt	CRISPR spacer
-ctggtgcgcgatggcggtgtggccggtgtcgt	Protospacer
 *. **** **.****************** **

32. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_AP021845 (Azospira sp. I09 plasmid pAZI09, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcagcagcaacagtacggccagcag	CRISPR spacer
caacagcaacaacagtccggccagcaa	Protospacer
* .*****.******* *********.

33. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP031851 (Klebsiella pneumoniae strain 121 plasmid pKP121-2, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcagcagcaacagtacggccagcag	CRISPR spacer
caaaatcagcagcagtacggccagcag	Protospacer
* . * *****.***************

34. spacer 37.2|5319802|27|CP025990|PILER-CR matches to AY328852 (Vibrio parahaemolyticus phage VP16T, partial sequence) position: , mismatch: 5, identity: 0.815

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cagcagcagcaacagtacgaacagcct	Protospacer
* *****************. ****  

35. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

cggatgtccgcgacggcggcct-cgcgggatgt	CRISPR spacer
cggatgtcagcgacggcgtcctccgcgtgctg-	Protospacer
******** ********* *** **** * ** 

36. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.829

-cgctcggcgcgcaccgcggcgagctcggc-gcgcag	CRISPR spacer
gcgc-gggcgcgcagcgcggcgagatcggcggcgcg-	Protospacer
 ***  ******** ********* ***** ****. 

37. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 6, identity: 0.812

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
gcgacctggacgcggacgtcctcgaacaggcg	Protospacer
*** **.********************   .*

38. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_015382 (Burkholderia gladioli BSR3 plasmid bgla_1p, complete sequence) position: , mismatch: 6, identity: 0.812

tgcgtgatg-gcggagatcgcctggcccactat	CRISPR spacer
-gcggcacgcgcggagatcgcctgggccagtat	Protospacer
 ***  *.* *************** *** ***

39. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017591 (Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ10, complete sequence) position: , mismatch: 6, identity: 0.812

tgcgtgatg-gcggagatcgcctggcccactat	CRISPR spacer
-gcgcaaagcgcggagatcgcctggcgcattat	Protospacer
 ***..* * **************** **.***

40. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049116 (Pantoea stewartii strain ZJ-FGZX1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tgcgtgatg-gcggagatcgcctggcccactat	CRISPR spacer
-gcgcaaagcgcggagatcgcctggcgcattat	Protospacer
 ***..* * **************** **.***

41. spacer 22.14|3492423|31|CP025990|CRT matches to MN693826 (Marine virus AFVG_250M656, complete genome) position: , mismatch: 6, identity: 0.806

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
tacaggtcatcgtcggggtctacgagtccaa	Protospacer
 ** **************.*******  ** 

42. spacer 22.14|3492423|31|CP025990|CRT matches to MN694627 (Marine virus AFVG_250M1035, complete genome) position: , mismatch: 6, identity: 0.806

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
tacaggtcatcgtcggggtctacgagtccaa	Protospacer
 ** **************.*******  ** 

43. spacer 22.14|3492423|31|CP025990|CRT matches to MN693710 (Marine virus AFVG_250M1034, complete genome) position: , mismatch: 6, identity: 0.806

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
tacaggtcatcgtcggggtctacgagtccaa	Protospacer
 ** **************.*******  ** 

44. spacer 24.5|3572196|31|CP025990|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

ggtgcg-gccggtcggacctgacggcgctccg	CRISPR spacer
-ccgcgcgccggtcggccctcacggcgctcgg	Protospacer
  .*** ********* *** ********* *

45. spacer 26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 6, identity: 0.824

cctggcggccttcacggcgtcggcgtagcagtgc	CRISPR spacer
tctggcggccttcacggcgtcggcgtctccgtcg	Protospacer
.*************************  * **  

46. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020900 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

47. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 6, identity: 0.806

--gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
aggccg--ggctcgaggccgagcttgacggcca	Protospacer
  ***.  *************** ** ****.*

48. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013526 (Rhizobium phaseoli strain R744 plasmid pRphaR744d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

49. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

50. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013589 (Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

51. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

52. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

53. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013531 (Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

54. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013536 (Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

55. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

56. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

57. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

58. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013584 (Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

59. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

60. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_010997 (Rhizobium etli CIAT 652 plasmid pC, complete sequence) position: , mismatch: 6, identity: 0.806

gccatcg-gctcgaggccgagcgtgtcggcta	CRISPR spacer
-tcgtcgtgctggagggcgagcgtgtcggctg	Protospacer
 .*.*** *** **** **************.

61. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP016617 (Microvirga ossetica strain V5/3m plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.806

-gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
aggca-cggctcgaggccgagcgcgacggttc	Protospacer
 * ** *****************.* ***.* 

62. spacer 30.1|4939798|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP006570 (Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence) position: , mismatch: 6, identity: 0.824

-tgcgatccctccccggtcggccgccgccgggcgc	CRISPR spacer
acgggatcgc-cctcgatcggccgccgccgggcgc	Protospacer
 .* **** * **.**.******************

63. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.812

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgcgagcagcaccgccaggatcgcgcccacga	Protospacer
*. **  ***** ***************** *

64. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP025613 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ccagacgatgacggccaggatcgcgccctgca	Protospacer
* .*****  ******************  **

65. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 6, identity: 0.812

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgcgagcagcaccgccaggatcgcgcccacga	Protospacer
*. **  ***** ***************** *

66. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.812

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ctggagccgcgcggccaggatcgcgcccgcca	Protospacer
* ***   **.*****************.***

67. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP016078 (Actinoalloteichus sp. GBA129-24 plasmid pGBA129-24a, complete sequence) position: , mismatch: 6, identity: 0.818

ccgcggcggtctgctcgacgtcgccgcgcgcac-	CRISPR spacer
cgtcggcgggctgctcgccgtcgccgc-cgccca	Protospacer
*  ****** ******* ********* *** * 

68. spacer 33.4|4974253|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013744 (Streptomyces sp. CdTB01 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

atcgaggaccaggtgcaggctgccggccggggc	CRISPR spacer
agcgaggaccaggcgcagggtgccggccgcctc	Protospacer
* ***********.***** *********   *

69. spacer 33.7|4974438|33|CP025990|CRISPRCasFinder,CRT matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 6, identity: 0.818

-cgcagccggcccggcggaggccaggccgatgat	CRISPR spacer
acgcgg-cagcccggcggcggcgaggccgatgac	Protospacer
 ***.* *.********* *** **********.

70. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP004365 (Komagataeibacter xylinus E25 plasmid pGX5, complete sequence) position: , mismatch: 6, identity: 0.769

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
cctcggcgacgactgcgcccagcccc	Protospacer
. ******************** .. 

71. spacer 33.8|4974319|26|CP025990|PILER-CR matches to NZ_CP041350 (Komagataeibacter xylinus strain CGMCC 17276 plasmid pB, complete sequence) position: , mismatch: 6, identity: 0.769

tgtcggcgacgactgcgcccaggttg	CRISPR spacer
cctcggcgacgactgcgcccagcccc	Protospacer
. ******************** .. 

72. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.812

cggatgtccgcgacggcggcctcgcgg-gatgt	CRISPR spacer
tggatgtccgcgccggcggcctcgagatggtg-	Protospacer
.*********** *********** *. *.** 

73. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.812

cggatgtccgcgacggcggcctcgcgg-gatgt	CRISPR spacer
tggatgtccgcgccggcggcctcgagatggtg-	Protospacer
.*********** *********** *. *.** 

74. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041206 (Rhizobium sp. NIBRBAC000502774 plasmid pMK-3, complete sequence) position: , mismatch: 6, identity: 0.812

tggagct-tcgaggaaaccgccgccgcaatcgg	CRISPR spacer
-gcagccgtcgaggaaaccgccgcagcactcga	Protospacer
 * ***. **************** *** ***.

75. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_019677 (Nostoc sp. PCC 7524 plasmid pNOS7524.01, complete sequence) position: , mismatch: 6, identity: 0.812

tggagcttcgaggaaaccgccgccg-caatcgg	CRISPR spacer
aggagcttcgacgaaaccaccgccgacgaacg-	Protospacer
 ********** ******.****** *.* ** 

76. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021356 (Rhodococcus sp. S2-17 plasmid pRB29, complete sequence) position: , mismatch: 6, identity: 0.812

-gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgcctccg-cggtggcggtgtggccggcgaggt	Protospacer
 ***. .* ******************.* ***

77. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 6, identity: 0.812

-gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgcctccg-cggtggcggtgtggccggcgaggt	Protospacer
 ***. .* ******************.* ***

78. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP054615 (Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

gcccgt-gccggtggcggtgtggccggtgtggt	CRISPR spacer
-cgcgtcgctggtggtggtgtggccggtgtagg	Protospacer
 * *** **.*****.**************.* 

79. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 6, identity: 0.812

gcccgt-gccggtggcggtgtggccggtgtggt	CRISPR spacer
-cgcgtcgctggtggtggtgtggccggtgtagg	Protospacer
 * *** **.*****.**************.* 

80. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to MT316461 (Streptomyces phage Galactica, complete genome) position: , mismatch: 6, identity: 0.812

gcccgtgccggtggcggtgtggccggtgtggt-	CRISPR spacer
taccggggcggtggcggtgtggcc-gtctggtt	Protospacer
  *** * **************** ** **** 

81. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP021373 (Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
gtccagcagcaacaggacggccagcgc	Protospacer
 . ************ *********. 

82. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

83. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

84. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

85. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

86. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

87. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

88. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

89. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

90. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

91. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

92. spacer 37.2|5319802|27|CP025990|PILER-CR matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

93. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

94. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

95. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

96. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

97. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

98. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

99. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

100. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

101. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

102. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

103. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

104. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

105. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

106. spacer 37.2|5319802|27|CP025990|PILER-CR matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

107. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

108. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

109. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

110. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

111. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

112. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

113. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

114. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

115. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

116. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

117. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

118. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

119. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

120. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

121. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

122. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

123. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

124. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

125. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

126. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

127. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

128. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

129. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

130. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

131. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

132. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

133. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

134. spacer 37.2|5319802|27|CP025990|PILER-CR matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

135. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

136. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

137. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

138. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

139. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

140. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

141. spacer 37.2|5319802|27|CP025990|PILER-CR matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcagcagcaacagtacggccagcag	CRISPR spacer
cacgcccagcaacagcacggccagcag	Protospacer
*     *********.***********

142. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.812

cggatgtccgcgacggcggcctcgcgg-gatgt	CRISPR spacer
tggatgtccgcgccggcggcctcgagatggtg-	Protospacer
.*********** *********** *. *.** 

143. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.812

cggatgtccgcgacggcggcctcgcgg-gatgt	CRISPR spacer
tggatgtccgcgccggcggcctcgagatggtg-	Protospacer
.*********** *********** *. *.** 

144. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.818

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gtgcgcagcggcgtccaggcggcggccccgctc	Protospacer
  ****.*********************  * *

145. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 6, identity: 0.818

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gtgcgcagcggcgtccaggcggcggccccgctc	Protospacer
  ****.*********************  * *

146. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MT952005 (Aeromonas phage BUCT551, complete genome) position: , mismatch: 6, identity: 0.818

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
cagtgcggcggcgtcctggcggcggccatgggc	Protospacer
***.************ **********    **

147. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024940 (Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence) position: , mismatch: 6, identity: 0.818

cagcgcggcggcgtccaggcggcg--gcccatcgc	CRISPR spacer
cagcgcggcggcggccaggccgcgcagacgatc--	Protospacer
************* ****** ***  * * ***  

148. spacer 41.15|5594462|32|CP025990|PILER-CR matches to MT711977 (Streptomyces phage Dagobah, complete genome) position: , mismatch: 6, identity: 0.812

cgtccgggacgcccagggcgtgat-ccgctccg	CRISPR spacer
gcgccggcacgcccagggcgtgatcccgctgc-	Protospacer
   **** **************** ***** * 

149. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 6, identity: 0.812

cgtccgggacgcccagggcgtgatccgctccg--	CRISPR spacer
cgtccgggtcgcccagggagtgat--gccgcgaa	Protospacer
******** ********* *****  **. **  

150. spacer 42.3|5600696|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.824

agcggcccggtcggagctgcacactccggaccgg--	CRISPR spacer
agcggcccggccggagcggcaca--ccgacccggat	Protospacer
**********.****** *****  ***. ****  

151. spacer 42.6|5600696|33|CP025990|PILER-CR matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.818

agcggcccggtcggagctgcacac---tccggaccg	CRISPR spacer
agcggcccggccggagcggcacaccgacccgga---	Protospacer
**********.****** ******   .*****   

152. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to NC_028802 (Mycobacterium phage UnionJack, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

153. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MG099937 (Mycobacterium phage Aragog, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

154. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MG099938 (Mycobacterium phage Archetta, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

155. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MH338241 (Mycobacterium phage Tarynearal, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

156. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MN586062 (Mycobacterium phage Lev2, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

157. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to NC_022973 (Mycobacterium phage Conspiracy, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

158. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to KF493882 (Mycobacterium phage Jovo, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

159. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to NC_041984 (Mycobacterium phage Tiger, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

160. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MG099949 (Mycobacterium phage Phlorence, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

161. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MG099944 (Mycobacterium phage ForGetIt, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

162. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to MG099934 (Mycobacterium phage AgentM, complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgttgacgaagtcgtgtcggtggaggag	Protospacer
*** *****.************* .  *

163. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to Z18946 (Mycobacterium phage L5 complete genome) position: , mismatch: 6, identity: 0.786

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
tgtggacgaggtcgtctcggtcgtcggg	Protospacer
.************** ***** **   *

164. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013109 (Sinorhizobium americanum strain CFNEI 73 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.788

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
gcggacatctggccggccgacagcggctatttc	Protospacer
*.************* ****** *****. .* 

165. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013053 (Sinorhizobium americanum CCGM7 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.788

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
gcggacatctggccggccgacagcggctatttc	Protospacer
*.************* ****** *****. .* 

166. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KU356480 (Vibrio parahaemolyticus strain VPS92 plasmid pVPS92-VEB, complete sequence) position: , mismatch: 7, identity: 0.788

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
cggcaaaactggccgcccgacacctgctgggtg	Protospacer
  * * * **************** ***** **

167. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053812 (Vibrio cholerae strain W6G plasmid pW6G, complete sequence) position: , mismatch: 7, identity: 0.788

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
cggcaaaactggccgcccgacacctgctgggtg	Protospacer
  * * * **************** ***** **

168. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053815 (Vibrio cholerae strain W7G plasmid pW7G, complete sequence) position: , mismatch: 7, identity: 0.788

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
cggcaaaactggccgcccgacacctgctgggtg	Protospacer
  * * * **************** ***** **

169. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN831184 (Vibrio cholerae isolate V. cholerae 116-14 plasmid pNDM-116-14, complete sequence) position: , mismatch: 7, identity: 0.788

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
cggcaaaactggccgcccgacacctgctgggtg	Protospacer
  * * * **************** ***** **

170. spacer 3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KU530220 (Streptomyces phage Xkcd426, complete genome) position: , mismatch: 7, identity: 0.788

gccgccgtgatccgcgcgtcctgcctcctccgc	CRISPR spacer
gccgccgtgatgcgcgcgtcctgctcggtcttc	Protospacer
*********** ************..  **. *

171. spacer 3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 7, identity: 0.788

gccgccgtgatccgcgcgtcctgcctc-ctccgc	CRISPR spacer
cccgccgtgatcggcgcgccctgccgcacaacg-	Protospacer
 *********** *****.****** * *  ** 

172. spacer 4.1|207439|29|CP025990|CRT matches to NZ_CP049358 (Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

gtggcgggttgacggacggccaccacctg	CRISPR spacer
atggcgggctgacggacggcctccagagt	Protospacer
.*******.************ ***    

173. spacer 4.1|207439|29|CP025990|CRT matches to NZ_CP031159 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence) position: , mismatch: 7, identity: 0.759

gtggcgggttgacggacggccaccacctg	CRISPR spacer
atggcgggctgacggacggcctccagagt	Protospacer
.*******.************ ***    

174. spacer 4.1|207439|29|CP025990|CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 7, identity: 0.759

gtggcgggttgacggacggccaccacctg	CRISPR spacer
gcggcgggttgacggaccgtcaccagggc	Protospacer
*.*************** *.*****    

175. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 7, identity: 0.8

-cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
ccgagcgg-gcgcaccgcgacgagctcggcgagcgc	Protospacer
 **  *** **********.*********** **. 

176. spacer 6.12|408965|35|CP025990|CRISPRCasFinder,CRT matches to NZ_CP051543 (Paracoccus sanguinis strain OM2164 plasmid pPspOM122, complete sequence) position: , mismatch: 7, identity: 0.8

tcctgcgcgtcccgcgcgtccggcgtcagcgccac	CRISPR spacer
tcctgcgcggcccgcgcgtccggcgtctgatagag	Protospacer
********* ***************** *    * 

177. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_048768 (Gordonia phage Chelms, complete genome) position: , mismatch: 7, identity: 0.781

gacaacggccgcgcggccagctcgacaaaccc--	CRISPR spacer
gccaacggcagcgcgggcagctcg--aagccgag	Protospacer
* ******* ****** *******  **.**   

178. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to MT986029 (Gordonia phage Linetti, complete genome) position: , mismatch: 7, identity: 0.781

gacaacggccgcgcggccagctcgacaaaccc--	CRISPR spacer
gccaacggcagcgcggacagctcg--aagccgag	Protospacer
* ******* ****** *******  **.**   

179. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 7, identity: 0.781

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatctcaccgatcctgcgccgcatgaccat	Protospacer
 ***************.*******  *   **

180. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 7, identity: 0.781

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatctcaccgatcctgcgccgcatgaccat	Protospacer
 ***************.*******  *   **

181. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 7, identity: 0.781

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatctcaccgatcctgcgccgcatgaccat	Protospacer
 ***************.*******  *   **

182. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_LR027555 (Epibacterium mobile isolate EPIB1 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.781

--gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tgccga--tcaccgatcccgcgccgccggtgatc	Protospacer
   ***  ******************.****. .

183. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 7, identity: 0.781

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatctcaccgatcctgcgccgcatgaccat	Protospacer
 ***************.*******  *   **

184. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP039693 (Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence) position: , mismatch: 7, identity: 0.781

gcgatc-tcaccgatcccgcgccgctggtggat	CRISPR spacer
-caatcgccaccgatcccgagccgctgctggca	Protospacer
 *.*** .*********** ******* ***  

185. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 7, identity: 0.781

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
gcctgccggacgcggacgtccttgaactggtc	Protospacer
** . *****************.*****  * 

186. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to JQ067093 (Pseudomonas phage PaMx74, partial genome) position: , mismatch: 7, identity: 0.781

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
aggacgcggacgcggacgacctcgacctcctc	Protospacer
. * * ************ ****** ***** 

187. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP040096 (Pantoea sp. SO10 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
tcatgccgtgatgttcgccggcggtggtttgc	Protospacer
*   ********* ************* .** 

188. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcggccgtggtggccgccggcggggcgccgg	Protospacer
.*********.***.********* * .*.**

189. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 7, identity: 0.781

tgcggccgtgatggtcgccggcggtggactgg--	CRISPR spacer
tgcggatgtgatggtcgccggcg--cgaccgacg	Protospacer
***** .****************   ***.*.  

190. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 7, identity: 0.781

tgcggccgtgatggtcgccggcggtggactgg--	CRISPR spacer
tgcggatgtgatggtcgccggcg--cgaccgacg	Protospacer
***** .****************   ***.*.  

191. spacer 8.7|478685|33|CP025990|PILER-CR,CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.788

gacaacggc--cgcgcggccagctcgacaaacccc	CRISPR spacer
--cggtggccgcgcgcggccagctcgactaacgcc	Protospacer
  *...***  ***************** *** **

192. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP021029 (Rhizobium sp. TAL182 plasmid pRetTAL182e, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

193. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013600 (Rhizobium sp. N741 plasmid pRspN741e, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

194. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013504 (Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

195. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013510 (Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

196. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013521 (Rhizobium sp. N113 plasmid pRspN113d, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

197. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013494 (Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

198. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013515 (Rhizobium sp. N1314 plasmid pRspN1314d, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

199. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013594 (Rhizobium sp. N871 plasmid pRspN871d, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

200. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP013605 (Rhizobium sp. N731 plasmid pRspN731d, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatctcaccgatcccgcgccgctggtggatc--	CRISPR spacer
tcgatgtcaccgatcccgagccgctgcc--atcgg	Protospacer
 **** ************ ******* .  ***  

201. spacer 8.11|478929|33|CP025990|PILER-CR,CRT matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 7, identity: 0.788

gcgccccggacgcggacgtcctcgaactcctga	CRISPR spacer
gcgacctggacgcggacgtcctcgaacaggcgc	Protospacer
*** **.********************   .* 

202. spacer 8.12|478990|33|CP025990|PILER-CR,CRT matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 7, identity: 0.788

tgcggccgtgatggtcgccggcgg--tggactggc	CRISPR spacer
tgcggcggtgatggtcgccagcgggctgcgcag--	Protospacer
****** ************.****  ** .* *  

203. spacer 8.12|478990|33|CP025990|PILER-CR,CRT matches to NZ_CP046575 (Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence) position: , mismatch: 7, identity: 0.788

tgcggccgtgatggtcgccggcgg--tggactggc	CRISPR spacer
tgcggcggtgatggtcgccagcgggctgcgcag--	Protospacer
****** ************.****  ** .* *  

204. spacer 9.16|482147|32|CP025990|CRT matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 7, identity: 0.781

cgtggtcggacgtggtgtcgatcggcatgctt	CRISPR spacer
cacggtcgaacgtggtgtcgatccgcgggatt	Protospacer
*..*****.************** **. * **

205. spacer 12.13|718421|36|CP025990|PILER-CR,CRISPRCasFinder matches to NZ_CP016288 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.806

--gccacggacctgcgtgccgccgccgcagaggacgag	CRISPR spacer
cagctccg--cctgcgtgccgccgccgctgacgacgat	Protospacer
  **. **  ****************** ** ***** 

206. spacer 13.4|792104|35|CP025990|PILER-CR,CRT matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 7, identity: 0.8

caccgcatcgccctcaccgacatcgacgccctcgc---	CRISPR spacer
caccgcatcgcccgcaccggcat---cgccctggtgcc	Protospacer
************* *****.***   ****** *.   

207. spacer 13.17|792105|34|CP025990|CRISPRCasFinder matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 7, identity: 0.794

----accgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
gtgaaccac----ccctcaccgacctcgacgacctcgc	Protospacer
    ***.*    *********** ****** ******

208. spacer 13.17|792105|34|CP025990|CRISPRCasFinder matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 7, identity: 0.794

accgcatcgccctcaccgacatcgacgccctcgc---	CRISPR spacer
accgcatcgcccgcaccggcat---cgccctggtgcc	Protospacer
************ *****.***   ****** *.   

209. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013918 (Sphingomonas sp. LK11 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
tcggtgacggcggcgatcgcctggcccacccg	Protospacer
*  ****.***** ***************.  

210. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013918 (Sphingomonas sp. LK11 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
tcggtgacggcggcgatcgcctggcccacccg	Protospacer
*  ****.***** ***************.  

211. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044976 (Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
ggcgtgatgccggagatcgcctggctcgatga	Protospacer
 ******** ***************.*. *. 

212. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 7, identity: 0.781

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
gcgccaccggccggccgcagccgcacgagcag	Protospacer
 ******* ********** ******   * *

213. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to NZ_AP022849 (Bosea sp. ANAM02 plasmid pANAM02, complete sequence) position: , mismatch: 7, identity: 0.781

ccgcca-cctgccggccgcatccgcaccccccg	CRISPR spacer
-agcgaggccgccggccgcatccgcacggcccg	Protospacer
  ** *  *.*****************  ****

214. spacer 22.9|3492088|34|CP025990|CRT matches to NZ_CP025410 (Paracoccus sp. BM15 plasmid pBM152, complete sequence) position: , mismatch: 7, identity: 0.794

agcctgt-atgacctgctcgccgccaagaacggat	CRISPR spacer
-gcccatgatgacctgctcgccgccaagcgcggcc	Protospacer
 ***..* ******************** .*** .

215. spacer 22.14|3492423|31|CP025990|CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.774

--aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
gcaacgaa--atcttcggggcctacgaggacat	Protospacer
  *** ..  *** ******************.

216. spacer 22.14|3492423|31|CP025990|CRT matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 7, identity: 0.774

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
acaccgtcatcgtcgggcccgacgaggaatc	Protospacer
*  * ************ ** *******  *

217. spacer 24.1|3572195|32|CP025990|PILER-CR matches to NC_012521 (Rhodococcus opacus B4 plasmid pROB02, complete sequence) position: , mismatch: 7, identity: 0.781

gggtgcggccggtcggacctgacggcgctccg	CRISPR spacer
gggtgctgccggtcggaccggacgaagttcga	Protospacer
****** ************ ****. *.** .

218. spacer 24.1|3572195|32|CP025990|PILER-CR matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

gggtgcg-gccggtcggacctgacggcgctccg	CRISPR spacer
-accgcgcgccggtcggccctcacggcgctcgg	Protospacer
 . .*** ********* *** ********* *

219. spacer 24.5|3572196|31|CP025990|CRISPRCasFinder matches to NC_012521 (Rhodococcus opacus B4 plasmid pROB02, complete sequence) position: , mismatch: 7, identity: 0.774

ggtgcggccggtcggacctgacggcgctccg	CRISPR spacer
ggtgctgccggtcggaccggacgaagttcga	Protospacer
***** ************ ****. *.** .

220. spacer 24.8|3572379|31|CP025990|CRISPRCasFinder matches to NZ_CP020952 (Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence) position: , mismatch: 7, identity: 0.774

aggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
tggacaatgtcgtgcgcaacggacccggtgt	Protospacer
 ***   *****.******* ********* 

221. spacer 25.5|3609535|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 7, identity: 0.788

gtcctatgtggagggggcggcggtcgggttcgc	CRISPR spacer
ggccgggctggaaggggcggcggtcggcttcgc	Protospacer
* ** .  ****.************** *****

222. spacer 25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.774

tccgttctcacccagcggcggcgtcgtcgtc	CRISPR spacer
gaggtgttcaccccgcggcggcgtcctcgtc	Protospacer
   ** .****** *********** *****

223. spacer 25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.774

tccgttctcacccagcggcggcgtcgtcgtc	CRISPR spacer
gaggtgttcaccccgcggcggcgtcctcgtc	Protospacer
   ** .****** *********** *****

224. spacer 26.3|3610419|38|CP025990|CRT matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 7, identity: 0.816

ggaccctggcggccttcacggcgtcggcgtagcagtgc	CRISPR spacer
ggtctctggcggccttcacggcgtcggcgtctccgtcg	Protospacer
** *.*************************  * **  

225. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 7, identity: 0.774

--gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tggttgt--gctcgaggccgagagtgtcggctt	Protospacer
  *...*  ************* ********* 

226. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020568 (Kitasatospora aureofaciens strain DM-1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tcgaccagcccgaggccgagcgtgtcggcgc	Protospacer
 * *.*.**.*******************  

227. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tcgctttgctcgaagccgagcatgtcggcta	Protospacer
 *  *. ******.*******.*********

228. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tcgctttgctcgaagccgagcatgtcggcta	Protospacer
 *  *. ******.*******.*********

229. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tcgctttgctcgaagccgagcatgtcggcta	Protospacer
 *  *. ******.*******.*********

230. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN234205 (Mycobacterium phage Veliki, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

231. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH727544 (Mycobacterium phage Dalmuri, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

232. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH001453 (Mycobacterium phage Adonis, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

233. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to KX683428 (Mycobacterium phage TBond007, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcaa	Protospacer
**  . ******.********* ****** *

234. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to JF704105 (Mycobacterium phage Adephagia, complete sequence) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

235. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN234182 (Mycobacterium phage Geraldini, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

236. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN234198 (Mycobacterium phage Zavala, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

237. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF140412 (Mycobacterium phage Jeckyll, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

238. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to KY380102 (Mycobacterium phage CREW, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

239. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to KX585253 (Mycobacterium phage HedwigODU, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

240. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN234230 (Mycobacterium phage Atiba, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

241. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF140430 (Mycobacterium phage Tachez, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

242. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF140428 (Mycobacterium phage Slimphazie, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

243. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MK460247 (Mycobacterium phage YoureAdopted, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

244. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to JN185608 (Mycobacterium virus JAWS, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

245. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN234231 (Mycobacterium phage Rapunzel97, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

246. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF373841 (Mycobacterium phage Hurricane, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcaa	Protospacer
**  . ******.********* ****** *

247. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_014458 (Mycobacterium phage Angelica, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

248. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN908692 (Mycobacterium Phage BGlluviae, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

249. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_023747 (Mycobacterium phage BarrelRoll, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

250. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to KR080206 (Mycobacterium phage ShedlockHolmes, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcaa	Protospacer
**  . ******.********* ****** *

251. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH536821 (Mycobacterium phage Homura, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

252. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_014459 (Mycobacterium virus CrimD, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

253. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF668267 (Mycobacterium phage Apocalypse, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

254. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH697578 (Mycobacterium phage Belladonna, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

255. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH509444 (Mycobacterium phage BEEST, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

256. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN369742 (Mycobacterium phage Spock, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

257. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_042325 (Mycobacterium virus Pixie, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcaa	Protospacer
**  . ******.********* ****** *

258. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MK112537 (Mycobacterium Phage Capricorn, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

259. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NC_026603 (Mycobacterium phage Keshu, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcaa	Protospacer
**  . ******.********* ****** *

260. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN369746 (Mycobacterium phage Inky, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

261. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH051246 (Mycobacterium phage ActinUp, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

262. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MN234197 (Mycobacterium phage Ramen, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

263. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MH371113 (Mycobacterium phage Beezoo, complete genome) position: , mismatch: 7, identity: 0.774

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gcgccgggctcggggccgagcgggtcggcca	Protospacer
**  . ******.********* ******.*

264. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 7, identity: 0.781

gtgacctggccgttgccgacgaacgcgttcac-----	CRISPR spacer
gtgaccgggccgttgtcgacgaa-----tcacggcga	Protospacer
****** ********.*******     ****     

265. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 7, identity: 0.781

gtgacctggccgttgccgacgaacgcgttcac-----	CRISPR spacer
gtgaccgggccgttgtcgacgaa-----tcacggcga	Protospacer
****** ********.*******     ****     

266. spacer 28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029362 (Streptomyces globisporus strain TFH56 plasmid pTFSG1, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgccgggtcggggaccacgtccacgtcgcc	CRISPR spacer
agaacacggtcggggaccccgtccacgtcgcg	Protospacer
 * .*  *********** ************ 

267. spacer 28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgccgggtcggggaccacgtccacgtcgcc	CRISPR spacer
agcgccgcgtcggggaacacgtccagcacggc	Protospacer
 ****** ******** ********   ** *

268. spacer 28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgccgggtcggggaccacgtccacgtcgcc	CRISPR spacer
agcgccgcgtcggggaacacgtccagcacggc	Protospacer
 ****** ******** ********   ** *

269. spacer 28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.781

tgcgccgggtcggggaccacgtccacgtcgcc	CRISPR spacer
agcgccgcgtcggggaacacgtccagcacggc	Protospacer
 ****** ******** ********   ** *

270. spacer 31.1|4968642|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026653 (Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcagg-gtccggtgtgtggggcggcctggtg	CRISPR spacer
-gtcaggagtccggcgtgtggggcggcttggac	Protospacer
 . **** ******.************.***  

271. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_018532 (Arthrobacter sp. Rue61a plasmid p232, complete sequence) position: , mismatch: 7, identity: 0.781

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgtcccgagcacggacaggaccgcgcccaccg	Protospacer
*.   ********* *****.**********.

272. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 7, identity: 0.781

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gaggaccagcccggccaggatcgcagcgacga	Protospacer
 ***** *** *************. * ** *

273. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to MT108725 (Pseudomonas phage Epa5, complete genome) position: , mismatch: 7, identity: 0.781

caggac--gagcacggccaggatcgcgcccacca	CRISPR spacer
--ggtctggagcacggccaggatcacgctcagcg	Protospacer
  ** *  ****************.***.** *.

274. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.781

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
ggggcgcaggtcatcatcaccggtcggcggca	Protospacer
**  ***.*******.************   *

275. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 7, identity: 0.781

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
ggcgaccgggtcgtcgtcatcggtcggctgac	Protospacer
***   ******.******.********* * 

276. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.781

ggctcgcgggtcatcgtcaccggtcggctcaa---	CRISPR spacer
ggctcgcgggtctacgtcaccg---gggccaacga	Protospacer
************  ********   ** .***   

277. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.781

ggctcgcgggtcatcgtcaccggtcggctcaa---	CRISPR spacer
ggctcgcgggtctacgtcaccg---gggccaacga	Protospacer
************  ********   ** .***   

278. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.781

atcgtgcagcgtcgcccggccggcaacacggc	CRISPR spacer
ctcgcgcagcgacgcccggccggcaggaccgg	Protospacer
 ***.****** *************. ** * 

279. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_LR134455 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence) position: , mismatch: 7, identity: 0.788

ccgcg-gcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
-ggtgcgcggtctgcccgacgccgccgcgcggat	Protospacer
  *.* *********.*****.********* *.

280. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP040765 (Paracoccus sp. 2251 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
catcgaaggtctggtcgacgtcaccgcgcgcaa	Protospacer
*  **. ****** ********.********* 

281. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.788

ccgcggcggtctgctcgacgtcgccgcgc-gcac	CRISPR spacer
cctgcgcggcccgctcgacgtcgccgcgctgcg-	Protospacer
**   ****.*.***************** **. 

282. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.788

-ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
gctgc-gcggccggctcgacgtcgccgcgctggc	Protospacer
 *.** ****.* *****************  .*

283. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.788

-ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
gctgc-gcggccggctcgacgtcgccgcgctggc	Protospacer
 *.** ****.* *****************  .*

284. spacer 33.4|4974253|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP011248 (Agrobacterium tumefaciens strain Ach5 plasmid pAt, complete sequence) position: , mismatch: 7, identity: 0.788

atcgagg-accaggtgcaggctgccggccggggc	CRISPR spacer
-tcgggataccgggttcaggctgccggccgggcg	Protospacer
 ***.*. ***.*** ****************  

285. spacer 33.4|4974253|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP032919 (Agrobacterium tumefaciens strain 15955 plasmid pAt15955, complete sequence) position: , mismatch: 7, identity: 0.788

atcgagg-accaggtgcaggctgccggccggggc	CRISPR spacer
-tcgggataccgggttcaggctgccggccgggcg	Protospacer
 ***.*. ***.*** ****************  

286. spacer 33.4|4974253|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP033029 (Agrobacterium tumefaciens strain A6 plasmid pAtA6, complete sequence) position: , mismatch: 7, identity: 0.788

atcgagg-accaggtgcaggctgccggccggggc	CRISPR spacer
-tcgggataccgggttcaggctgccggccgggcg	Protospacer
 ***.*. ***.*** ****************  

287. spacer 33.4|4974253|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

atcgaggaccaggtgcaggctgccggccggggc	CRISPR spacer
atcgcggaccagctgcaggctgcccagcggcgg	Protospacer
**** ******* *********** . *** * 

288. spacer 33.7|4974438|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP035513 (Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence) position: , mismatch: 7, identity: 0.788

cgcagccggcccggcggaggccaggccgatgat	CRISPR spacer
cgtgtccagcccggcggaggccagcccgataac	Protospacer
**.. **.**************** *****.*.

289. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.781

-cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aacggtg-ccgcgacggccgcctggcgggatgc	Protospacer
   *.** ********** **** ********.

290. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.781

cggatgtccgcgacggcggcctcgcg-ggatgt	CRISPR spacer
ccgacgtccgcgacggcgacctcgcatcggtg-	Protospacer
* **.*************.******.  *.** 

291. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020613 (Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aggacggccgcgacggcggcctcggtgggcgt	Protospacer
 ***.* *****************  **..**

292. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 7, identity: 0.781

tggagct----tcgaggaaaccgccgccgcaatcgg	CRISPR spacer
----gcttcgctcgaggaaaccgccgccgcgctcga	Protospacer
    ***    *******************. ***.

293. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022751 (Sphingobium hydrophobicum strain C1 plasmid p5, complete sequence) position: , mismatch: 7, identity: 0.781

--tggagcttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
cttgaaac--cgaggaaaccgccgccgccctcgc	Protospacer
  **.*.*  ******************  *** 

294. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcccgtgccggtggcgcagtggccgtgggcga	Protospacer
****************  *******  *  * 

295. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_AP019820 (Enterobacter hormaechei subsp. hoffmannii strain OIPH-N069 plasmid pN069_3, complete sequence) position: , mismatch: 7, identity: 0.781

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcccgtgccggtggcggtgtttccgttaatgg	Protospacer
********************  *** *.  * 

296. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to MK524177 (Escherichia phage PHB10, complete genome) position: , mismatch: 7, identity: 0.781

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcccgtgccggtggcggtgtttccgttaatgg	Protospacer
********************  *** *.  * 

297. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 7, identity: 0.781

gcccgt--gccggtggcggtgtggccggtgtggt	CRISPR spacer
--cagttggccggtggcggtgttggcggtgtcgg	Protospacer
  * **  ************** * ****** * 

298. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to CP003952 (Rhodococcus opacus PD630 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.781

gcccg---tgccggtggcggtgtggccggtgtggt	CRISPR spacer
---cgagtcggcggtggcggtgtggccggcgaggt	Protospacer
   **   .* ******************.* ***

299. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_004680 (Mycobacterium phage Che8, complete genome) position: , mismatch: 7, identity: 0.781

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcaggtcccggtggcggtggggccggtcggga	Protospacer
**  ** ************ *******  ** 

300. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to AY129330 (Mycobacterium virus Che8, complete genome) position: , mismatch: 7, identity: 0.781

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcaggtcccggtggcggtggggccggtcggga	Protospacer
**  ** ************ *******  ** 

301. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.781

-cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aacggtg-ccgcgacggccgcctggcgggatgc	Protospacer
   *.** ********** **** ********.

302. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.781

cggatgtccgcgacggcggcctcgcg-ggatgt	CRISPR spacer
ccgacgtccgcgacggcgacctcgcatcggtg-	Protospacer
* **.*************.******.  *.** 

303. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020613 (Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aggacggccgcgacggcggcctcggtgggcgt	Protospacer
 ***.* *****************  **..**

304. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MK838113 (Aeromonas phage LAh_7, complete genome) position: , mismatch: 7, identity: 0.788

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
cagtgcggcggcgtcctggcggcggcaatgggc	Protospacer
***.************ *********     **

305. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024582 (Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

cagcgcggcggcgtccaggcggcggcc-catcgc	CRISPR spacer
gcgcgcagcgtcgtccaggcggcggccgcgacg-	Protospacer
  ****.*** **************** *. ** 

306. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 7, identity: 0.788

cagcgcggcggcgtccaggcggcggc--ccatcgc	CRISPR spacer
ctgcgcggcgccgtcaaggcggcggcggcgatg--	Protospacer
* ******** **** **********  * **   

307. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP021083 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI2, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gcacccggacgcccggggcgtgatccgctcac	Protospacer
   ** ********.***************  

308. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP024426 (Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gctgctggacggccagggcgtgatccgcgcca	Protospacer
  * * ***** **************** **.

309. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP020445 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gctgctggacggccagggcgtgatccgcgcca	Protospacer
  * * ***** **************** **.

310. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gctgctggacggccagggcgtgatccgcgcca	Protospacer
  * * ***** **************** **.

311. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gctgctggacggccagggcgtgatccgcgcca	Protospacer
  * * ***** **************** **.

312. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
ggtcggggacggccagggcgtgatgcaatgcg	Protospacer
 *** ****** ************ *. * **

313. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgg---gacgcccagggcgtgatccgctccg	CRISPR spacer
---ccaggccgtcgccgagggcgtgatccgccccg	Protospacer
   **.*   * **** **************.***

314. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
ggtcggaaccgtccagggcgtgattcgctccg	Protospacer
 *** *.. **.************.*******

315. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
catccggggcgcccagcgcgtgatcaggcccc	Protospacer
*.******.******* ******** * .** 

316. spacer 42.2|5600635|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP048283 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence) position: , mismatch: 7, identity: 0.788

ctcgacctcggctgcggggaga---tcggcctcccg	CRISPR spacer
ctcgacctcggcagcggcgagatcctcggtctt---	Protospacer
************ **** ****   ****.**.   

317. spacer 43.2|6196066|30|CP025990|PILER-CR matches to NZ_CP042535 (Citrobacter freundii strain E51 plasmid pE51_001, complete sequence) position: , mismatch: 7, identity: 0.767

gactcctcgtgtaccacggcccgcagtact-	CRISPR spacer
ttcgcctcgtctaccacggcccgca-tatgg	Protospacer
  * ****** ************** **.  

318. spacer 43.2|6196066|30|CP025990|PILER-CR matches to NZ_CP026546 (Cupriavidus metallidurans strain Ni-2 plasmid unnamed2) position: , mismatch: 7, identity: 0.767

gactcctcgtgtaccacggcccgcagtact-	CRISPR spacer
ttcgcctcgtctaccacggcccgca-tatgg	Protospacer
  * ****** ************** **.  

319. spacer 43.5|6196115|33|CP025990|CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.788

gctgcgcccgcgccgcacgccggtccgccggag	CRISPR spacer
ggtgcgcccgcggcgcacgccggtacgctcgcc	Protospacer
* ********** *********** ***. *  

320. spacer 44.3|6577413|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to MH834619 (Arthrobacter phage Maureen, complete genome) position: , mismatch: 7, identity: 0.788

agcgattcgttcagccggatttccgacaggagc	CRISPR spacer
cgctcttcgttcagccggatctccgacagggcg	Protospacer
 **  ***************.*********.  

321. spacer 44.3|6577413|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_048115 (Arthrobacter phage Liebe, complete genome) position: , mismatch: 7, identity: 0.788

agcgattcgttcagccggatttccgacaggagc	CRISPR spacer
cgctcttcgttcagccggatctccgacagggcg	Protospacer
 **  ***************.*********.  

322. spacer 44.4|6577474|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022566 (Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence) position: , mismatch: 7, identity: 0.788

tccgtact-gagcgccttgacggcgcggatctca	CRISPR spacer
-gagtgctcgatcgccatgacggcgcggatctcg	Protospacer
   **.** ** **** ****************.

323. spacer 45.1|6584161|33|CP025990|CRISPRCasFinder,CRT matches to MT451981 (Streptomyces phage Vondra, complete genome) position: , mismatch: 7, identity: 0.788

gtgcatg---atctcggcggcgctgacgaggtagcc	CRISPR spacer
---caagtccagctcggcggcgcggtcgaggtagcc	Protospacer
   ** *   * *********** * **********

324. spacer 45.1|6584161|33|CP025990|CRISPRCasFinder,CRT matches to MT451982 (Streptomyces phage Cumberbatch, complete genome) position: , mismatch: 7, identity: 0.788

gtgcatg---atctcggcggcgctgacgaggtagcc	CRISPR spacer
---caagtccagctcggcggcgcggtcgaggtagcc	Protospacer
   ** *   * *********** * **********

325. spacer 45.2|6584222|34|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 7, identity: 0.794

---ctcgggcaggtgtgcgtgcgaggcgatctcgccc	CRISPR spacer
ggcctcg---aggtgtgcgcgcgaggcgacctcgggc	Protospacer
   ****   *********.*********.****  *

326. spacer 46.1|6740139|28|CP025990|CRISPRCasFinder matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.75

cgtggacgaggtcgtgtcggtggtaccg	CRISPR spacer
cgtggacgagatcgtgacggtggaggac	Protospacer
**********.***** ****** .   

327. spacer 1.1|123621|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024309 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3b, complete sequence) position: , mismatch: 8, identity: 0.758

gtggacatctggccgcccgacaccggctggctg	CRISPR spacer
cgggacatctggccggccgacagcggctatttc	Protospacer
  ************* ****** *****. .* 

328. spacer 1.2|123682|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 8, identity: 0.758

gacttcgccgccgtggaggtttccgctgatgac	CRISPR spacer
ggcgaccgggccgtcgaggtttccgctggtgac	Protospacer
*.*  *   ***** *************.****

329. spacer 1.4|123804|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KP282680 (Sulfolobales Virus YNP2 strain SYV2, complete genome) position: , mismatch: 8, identity: 0.758

gccgtcaaggtcaatcggggtgccctgcatcgg	CRISPR spacer
ggcgtcaaggtaaatcggggtgtccttgttcaa	Protospacer
* ********* **********.***   **..

330. spacer 2.4|133695|33|CP025990|PILER-CR,CRT matches to NZ_CP014598 (Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

gtgccgctgatcccccgcagcgatcgtgatgga	CRISPR spacer
ctgccgctgatccccgccagcgatcgccccggc	Protospacer
 **************  *********.  .** 

331. spacer 2.4|133695|33|CP025990|PILER-CR,CRT matches to NZ_CP038031 (Rhodococcus ruber strain R1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

gtgccgctgatcccccgcagcgatcgtgatgga	CRISPR spacer
ccgccgcggatccaccgcagcgatcgttgtcgt	Protospacer
 .***** ***** ************* .* * 

332. spacer 2.4|133695|33|CP025990|PILER-CR,CRT matches to NC_005073 (Rhodococcus erythropolis linear plasmid pBD2, complete sequence) position: , mismatch: 8, identity: 0.758

gtgccgctgatcccccgcagcgatcgtgatgga	CRISPR spacer
ctggagctgatcccccgcagcgatgatgaggtc	Protospacer
 **  ******************* .*** *  

333. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

334. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

335. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

336. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

337. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

338. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

339. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

340. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

341. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

342. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

343. spacer 3.1|135390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.758

tatgccggcgccctcccgggcggttcggatcgc	CRISPR spacer
ggtgcgggcgccgtcccgggcggttcgcgccgg	Protospacer
 .*** ****** ************** ..** 

344. spacer 3.5|135635|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 8, identity: 0.758

gccgccgtgatccgcgcgtcctgcctcctccgc	CRISPR spacer
accgccgcgatcagcgcgtcctgcccgttgggc	Protospacer
.******.**** ************. .*  **

345. spacer 4.1|207439|29|CP025990|CRT matches to NC_017791 (Deinococcus gobiensis I-0 plasmid P2, complete sequence) position: , mismatch: 8, identity: 0.724

gtggcgggttgacggacggccaccacctg	CRISPR spacer
agatcgggatgacgaacggccaccaccac	Protospacer
. . **** *****.************  

346. spacer 4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP025613 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

tcgccgccgccgctggcccggacggccggtggc	CRISPR spacer
gcatggcggccgctggcccggtcggccggagcc	Protospacer
 *.. ** ************* ******* * *

347. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP023721 (Rhodococcus sp. H-CA8f plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
atcgccaacgaccgccaccggcaggccaccgtc	Protospacer
******* ***********.***** *.  ..*

348. spacer 4.9|207925|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 8, identity: 0.765

cgaccgtgctctccgacgaaccggacccggaccc-----	CRISPR spacer
cgaccgtgctgtccgacgaaccg-----ggattcatcgg	Protospacer
********** ************     ***..*     

349. spacer 4.10|207987|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_AP022849 (Bosea sp. ANAM02 plasmid pANAM02, complete sequence) position: , mismatch: 8, identity: 0.758

gcagcgcctcggtgtgatccgccgtggcctgcg	CRISPR spacer
gcagcgcctcagtgtgatccgacggcggatcct	Protospacer
**********.********** **  *  * * 

350. spacer 4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.758

ggccgcatccggatcgtgctggtcggcgggtcc	CRISPR spacer
gtgcgcaaccagatcgtgctggtcggcatttcg	Protospacer
*  **** **.****************.  ** 

351. spacer 4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

ggccgcatccggatcgtgctggtcggcgggtcc	CRISPR spacer
gtgcgcaaccagatcgtgctggtcggcatttcg	Protospacer
*  **** **.****************.  ** 

352. spacer 5.1|369283|33|CP025990|CRISPRCasFinder matches to CP006582 (Mesorhizobium huakuii 7653R plasmid pMHa, complete sequence) position: , mismatch: 8, identity: 0.758

caactaccgggcgctcaaaactttcttcggctg	CRISPR spacer
cgcagaccgcccgctcaaaactttcttcgccgg	Protospacer
*.   ****  ****************** * *

353. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.771

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
cactcggcgcgcaccgcggcgcgcgcgctgtcgag	Protospacer
*.******************* ** ** .*.  **

354. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_002699 (Frankia sp. CpI1 plasmid pFQ12, complete plasmid sequence) position: , mismatch: 8, identity: 0.771

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcggcgcgcaccgcggcgacctccgccgccag	Protospacer
.*  ****************** *** **   ***

355. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacggccgcgcggccagctcgacaaaccc	CRISPR spacer
ttgttcagccgcgcggccagctcgacataacc	Protospacer
     *.******************** * **

356. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP041043 (Paracoccus sp. AK26 plasmid pAK3, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacggccgcgcggccagctcgacaaaccc	CRISPR spacer
gcatccagccgcgcggccagttcgacgaaccg	Protospacer
*    *.*************.*****.**** 

357. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

358. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

359. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

360. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

361. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

362. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

363. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

364. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

365. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

366. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

367. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

368. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

369. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

370. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

371. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

372. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

373. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

374. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

375. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

376. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

377. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

gacaacg----gccgcgcggccagctcgacaaaccc	CRISPR spacer
----acgccataccgcgcgggctgctcgacaaacct	Protospacer
    ***    .******** * ************.

378. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 8, identity: 0.75

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
gcgatctcacggatcccgcgctgctccgaggc	Protospacer
********** **********.***   .*..

379. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NC_012854 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence) position: , mismatch: 8, identity: 0.75

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgctctcaccgattccgcgccgctgatcatc	Protospacer
 ** **********.***********.* . .

380. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP020900 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence) position: , mismatch: 8, identity: 0.75

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
gcgctctcatcgatcccgcgccgataaaggcc	Protospacer
*** *****.************* *.. ** .

381. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP015232 (Epibacterium mobile F1926 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

--gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tgccga--tcacagatcccgcgccgccggtgatc	Protospacer
   ***  **** *************.****. .

382. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NC_042088 (Gordonia phage Gustav, complete genome) position: , mismatch: 8, identity: 0.75

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcacgctcaccgatcccgcggagctggtccat	Protospacer
 *.  ***************  ******  **

383. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP026382 (Sphingopyxis sp. MG plasmid pCMS1, complete sequence) position: , mismatch: 8, identity: 0.75

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
ttggccttcacgcggccgttctcgaactcctg	Protospacer
 .* **.  ****** ***.************

384. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
tgccgccgggatggtcgccggcggcgccatcc	Protospacer
*** **** ***************.*   *  

385. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP012575 (Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcgggcgtgatggacgccggcggaccagtcg	Protospacer
.**** ******** *********   * * *

386. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP012575 (Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcctgc	Protospacer
 ***********  **********    *** 

387. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP047052 (Clavibacter michiganensis subsp. michiganensis strain MSF322 plasmid pMSF2, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcctgc	Protospacer
 ***********  **********    *** 

388. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to CP048046 (Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcgggcgtgatggacgccggcggaccagtcg	Protospacer
.**** ******** *********   * * *

389. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to CP048046 (Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcctgc	Protospacer
 ***********  **********    *** 

390. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_007961 (Nitrobacter hamburgensis X14 plasmid 3, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcggccgtggcggtcgccggcggcatgctga	Protospacer
.*********..************.. .***.

391. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP048050 (Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcgggcgtgatggacgccggcggaccagtcg	Protospacer
.**** ******** *********   * * *

392. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP048050 (Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcctgc	Protospacer
 ***********  **********    *** 

393. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP048048 (Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcgggcgtgatggacgccggcggaccagtcg	Protospacer
.**** ******** *********   * * *

394. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP048048 (Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcctgc	Protospacer
 ***********  **********    *** 

395. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_AP014686 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtggcggtcgccggcggcatgctga	Protospacer
 *********..************.. .***.

396. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_049489 (Arthrobacter phage DrYang, complete genome) position: , mismatch: 8, identity: 0.75

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
agcggccgtggtggtcgccgccgggaggcgcg	Protospacer
 *********.********* *** .*.*  *

397. spacer 8.7|478685|33|CP025990|PILER-CR,CRT matches to NZ_CP041043 (Paracoccus sp. AK26 plasmid pAK3, complete sequence) position: , mismatch: 8, identity: 0.758

gacaacggccgcgcggccagctcgacaaacccc	CRISPR spacer
gcatccagccgcgcggccagttcgacgaaccgc	Protospacer
*    *.*************.*****.**** *

398. spacer 8.11|478929|33|CP025990|PILER-CR,CRT matches to JQ067093 (Pseudomonas phage PaMx74, partial genome) position: , mismatch: 8, identity: 0.758

gcgccccggacgcggacgtcctcgaactcctga	CRISPR spacer
aggacgcggacgcggacgacctcgacctcctcc	Protospacer
. * * ************ ****** *****  

399. spacer 8.11|478929|33|CP025990|PILER-CR,CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 8, identity: 0.758

gcgccccggacgcggacgtcctcgaact---cctga	CRISPR spacer
aagacccggacccggtcgtcctcgaactgggcc---	Protospacer
. * ******* *** ************   **   

400. spacer 8.11|478929|33|CP025990|PILER-CR,CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 8, identity: 0.758

gcgccccggacgcggacgtcctcgaact---cctga	CRISPR spacer
aagacccggacccggtcgtcctcgaactgggcc---	Protospacer
. * ******* *** ************   **   

401. spacer 8.11|478929|33|CP025990|PILER-CR,CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 8, identity: 0.758

gcgccccggacgcggacgtcctcgaact---cctga	CRISPR spacer
aagacccggacccggtcgtcctcgaactgggcc---	Protospacer
. * ******* *** ************   **   

402. spacer 8.12|478990|33|CP025990|PILER-CR,CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.758

tgcggccgtgatggtcgccggcggtggactggc	CRISPR spacer
tgccgccgggatggtcgccggcggcgccatccc	Protospacer
*** **** ***************.*   *  *

403. spacer 9.15|482082|34|CP025990|CRT matches to DQ372923 (Bacteriophage mu1/6, complete genome) position: , mismatch: 8, identity: 0.765

tgcgcgaactcggcctcctccctcccgcgcccgc	CRISPR spacer
aggccgccctcggcctcctgccgcccgcgccccc	Protospacer
 *  **  *********** ** ********* *

404. spacer 9.15|482082|34|CP025990|CRT matches to NC_007967 (Streptomyces phage mu1/6, complete genome) position: , mismatch: 8, identity: 0.765

tgcgcgaactcggcctcctccctcccgcgcccgc	CRISPR spacer
aggccgccctcggcctcctgccgcccgcgccccc	Protospacer
 *  **  *********** ** ********* *

405. spacer 10.1|554801|33|CP025990|CRT matches to NZ_CP016620 (Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

atcatcggcctggcctccgccggcccggctgcg	CRISPR spacer
gtcatcggtctggccgccgccggcctgcccaag	Protospacer
.*******.****** *********.* *.. *

406. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP041653 (Streptomyces sp. RLB1-9 plasmid pRLB1-9.1, complete sequence) position: , mismatch: 8, identity: 0.765

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
accgccctggccccgcccgccgccgaccgggcgg	Protospacer
 ..********** ***.**********.* *.*

407. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_004719 (Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence) position: , mismatch: 8, identity: 0.765

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gaagccctggcccggcaggccgccgaccgcggca-	Protospacer
   *************  **********. * ** 

408. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_004719 (Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence) position: , mismatch: 8, identity: 0.765

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gaagccctggcccggcaggccgccgaccgcggca-	Protospacer
   *************  **********. * ** 

409. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_004719 (Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence) position: , mismatch: 8, identity: 0.765

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gaagccctggcccggcaggccgccgaccgcggca-	Protospacer
   *************  **********. * ** 

410. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_004719 (Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence) position: , mismatch: 8, identity: 0.765

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gaagccctggcccggcaggccgccgaccgcggca-	Protospacer
   *************  **********. * ** 

411. spacer 11.4|711870|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039220 (Piscirickettsia salmonis strain NVI 5692 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

cgctgccctgagccggttggcgatctgcacaga	CRISPR spacer
caccgccctgagccgtttggcgatctgcgagcc	Protospacer
*.*.*********** ************. .  

412. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051470 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

413. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_011960 (Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

414. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030273 (Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

415. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP047033 (Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

416. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_009040 (Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
ctcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
  ****  *******************    **    

417. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015290 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

418. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047039 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

419. spacer 11.6|711992|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015213 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence) position: , mismatch: 8, identity: 0.758

aacgcccggctgtaggcggttcgggcc----tggccc	CRISPR spacer
cgcgccgcgctgtaggcggttcgggccatcgtg----	Protospacer
 .****  *******************    **    

420. spacer 11.7|712053|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.758

ccgccgaccgggtgcgaaccgggttggacctcg	CRISPR spacer
tcgccgaccgggcgcgaacctggttggcggaca	Protospacer
.***********.******* ******    *.

421. spacer 13.4|792104|35|CP025990|PILER-CR,CRT matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 8, identity: 0.771

----caccgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
cgtgaaccac----ccctcaccgacctcgacgacctcgc	Protospacer
     ***.*    *********** ****** ******

422. spacer 13.17|792105|34|CP025990|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 8, identity: 0.765

accgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
gccgcctcgccctcaccgacctcgaccgccaggg	Protospacer
.**** ************** *****  **  * 

423. spacer 13.17|792105|34|CP025990|CRISPRCasFinder matches to NZ_CP045326 (Mycobacterium sp. THAF192 plasmid pTHAF192_a, complete sequence) position: , mismatch: 8, identity: 0.765

accgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
ccgacgtcgccctcaccgacaccaacgcccaagc	Protospacer
 * .*.***************.*.******  **

424. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 8, identity: 0.771

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
agatccagcagggcgtcgacgtcgacgacaatcac	Protospacer
   ******** *** *************  **.*

425. spacer 14.2|1142214|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to JQ067089 (Pseudomonas phage PaMx28, partial genome) position: , mismatch: 8, identity: 0.778

ccgagagggaggccaaggacgccgagaacgccgcga	CRISPR spacer
ctgccaaggaggccaaggccgccgagaaggccgcag	Protospacer
*.*  *.*********** ********* *****..

426. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417913 (Uncultured Caudovirales phage clone 9S_2, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

427. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417918 (Uncultured Caudovirales phage clone 7F_17, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

428. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417915 (Uncultured Caudovirales phage clone 8AX_8, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

429. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417914 (Uncultured Caudovirales phage clone 8S_2, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

430. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417896 (Uncultured Caudovirales phage clone 3S_18, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

431. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417912 (Uncultured Caudovirales phage clone 10AX_4, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

432. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417910 (Uncultured Caudovirales phage clone 2AX_5, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

433. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417916 (Uncultured Caudovirales phage clone 7S_13, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

434. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417911 (Uncultured Caudovirales phage clone 9AX_3, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

435. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417920 (Uncultured Caudovirales phage clone 10F_8, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

436. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to MF417898 (Uncultured Caudovirales phage clone 7AX_6, partial genome) position: , mismatch: 8, identity: 0.778

-gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
cccgccag-cagcggcagcagcgccggcaggtcccgc	Protospacer
  .***.* ***  *********************..

437. spacer 18.2|2981929|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017148 (Bosea vaviloviae strain Vaf18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gatgccctcgacatcggtcggcgtctcccctt	CRISPR spacer
cccgccctcgacctcggtcggcgtcgccgcgg	Protospacer
  .********* ************ ** *  

438. spacer 18.4|2982051|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.75

tcggacacggcgtaggcgacgccgcagctcac	CRISPR spacer
ccggacaccgcgtacgcgacgccgagcagcac	Protospacer
.******* ***** ********* .   ***

439. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.75

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
ccgccgccagccggccgcatccgccggcagcc	Protospacer
*****.** ***************   *  * 

440. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
ccgccacctgccgggcgcttccggcggaccag	Protospacer
************** *** ****     ** *

441. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
ccgccacctgccgggcgcttccggcggaccag	Protospacer
************** *** ****     ** *

442. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 8, identity: 0.75

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
gcacggcctgccggccgccgccgcaccccgcc	Protospacer
 *.* .************  ********* * 

443. spacer 22.9|3492088|34|CP025990|CRT matches to NZ_CP014598 (Yangia sp. CCB-MM3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgtatgacctgctcgccgccaagaacggat----	CRISPR spacer
ggcctctatgaccttctcgccgcc----acgcattcca	Protospacer
.**** ******** *********    *** **    

444. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
cgggctgcccggcgacatcgccgcgacggccgc	Protospacer
.  * *  **** *************** ****

445. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gccgatcggcgtggacatcgccgcgcagctcac	Protospacer
 ******* ** *************  *..*.*

446. spacer 22.13|3492357|33|CP025990|CRT matches to NC_014642 (Achromobacter xylosoxidans A8 plasmid pA82, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcga-cgtccgc	CRISPR spacer
catgagcgccgcggacatcgccgcgaccgtgca-	Protospacer
. .** ***** ************** *** *. 

447. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gccgatcggcgtggacatcgccgcgcagctcac	Protospacer
 ******* ** *************  *..*.*

448. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gccgatcggcgtggacatcgccgcgcagctcac	Protospacer
 ******* ** *************  *..*.*

449. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gccgatcggcgtggacatcgccgcgcagctcac	Protospacer
 ******* ** *************  *..*.*

450. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gccgatcggcgtggacatcgccgcgcagctcac	Protospacer
 ******* ** *************  *..*.*

451. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP026974 (Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcga-cgtccgc	CRISPR spacer
catgagcgccgcggacatcgccgcgaccgtgca-	Protospacer
. .** ***** ************** *** *. 

452. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gccgatcggcgtggacatcgccgcgcagctcac	Protospacer
 ******* ** *************  *..*.*

453. spacer 22.13|3492357|33|CP025990|CRT matches to MN586028 (Gordonia phage MelBins, complete genome) position: , mismatch: 8, identity: 0.758

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
acccgacgccgtggacagcgccgcgacgtcgac	Protospacer
 ** . ***** ***** ************ .*

454. spacer 22.14|3492423|31|CP025990|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
tcgaagccatcggcggggcctacgaggacgc	Protospacer
    .*.***** ****************.*

455. spacer 22.14|3492423|31|CP025990|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.742

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
gcgcccacatcgtcggggcctacgagcaccc	Protospacer
.  *   ******************* ** *

456. spacer 24.4|3572378|32|CP025990|PILER-CR matches to NZ_CP020952 (Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence) position: , mismatch: 8, identity: 0.75

gaggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
ctggacaatgtcgtgcgcaacggacccggtgt	Protospacer
  ***   *****.******* ********* 

457. spacer 24.6|3572257|31|CP025990|CRISPRCasFinder matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgggtgaatcccgctcggcgggcggcgc	CRISPR spacer
caccgggtgaatcccgcgcggcggccctgac	Protospacer
 .*************** ****** *   .*

458. spacer 24.6|3572257|31|CP025990|CRISPRCasFinder matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

agccgggtgaatcccgctcggcgggcggcgc	CRISPR spacer
gatcgtccgaatcacgctcggcaggcggcgc	Protospacer
...**  .***** ********.********

459. spacer 24.8|3572379|31|CP025990|CRISPRCasFinder matches to CP052219 (Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-2, complete sequence) position: , mismatch: 8, identity: 0.742

aggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
gcgcacttgacgcgcgcaaccgacgcgtagc	Protospacer
. * ***** ************** **  * 

460. spacer 24.8|3572379|31|CP025990|CRISPRCasFinder matches to NZ_CP024642 (Klebsiella michiganensis strain F107 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

aggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
gcgcacttgacgcgcgcaaccgacgcgtagc	Protospacer
. * ***** ************** **  * 

461. spacer 25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 8, identity: 0.742

tccgttctcacccagcggcggcgtcgtcgtc	CRISPR spacer
gctgggctcacccagcggcggcgccgacggt	Protospacer
 *.*  *****************.** ** .

462. spacer 25.9|3609777|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH588547 (Caulobacter phage CcrSC, complete genome) position: , mismatch: 8, identity: 0.758

ccgtatccggg-gatggccggcagggtcccgggg	CRISPR spacer
-agggcctgggcgatggccggcagggtcacgggt	Protospacer
  * ..*.*** **************** **** 

463. spacer 26.9|3610362|33|CP025990|PILER-CR,CRISPRCasFinder matches to NZ_LR134450 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence) position: , mismatch: 8, identity: 0.758

ttcgacgggcagcggctgtttctcacccagtcg	CRISPR spacer
ttcgacgggccgcggatgtttctcaacgcgcac	Protospacer
********** **** ********* *  *.  

464. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_AP017899 (Sphingopyxis sp. FD7 plasmid pSFD01, complete sequence) position: , mismatch: 8, identity: 0.742

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
cagatcggctcaaggccgagcgcgtcgtgtt	Protospacer
   ********.**********.****  * 

465. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.742

--gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tggttgt--gctcgaggccgaaagtgtcggctt	Protospacer
  *...*  ************. ********* 

466. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
agctgcagcgcgaggccgagcgtgtcggcgt	Protospacer
. *  *.** *******************  

467. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP039640 (Azospirillum sp. TSH100 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
ttgcccggctcgaggccgagcatgacggcaa	Protospacer
 .  .****************.** **** *

468. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP045288 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff1, complete sequence) position: , mismatch: 8, identity: 0.742

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tccatcgcctccaggccgagcgtgcgcgcag	Protospacer
 ****** *** ************.  ** .

469. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MG962364 (Mycobacterium phage Deby, complete genome) position: , mismatch: 8, identity: 0.742

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
acgccgggctcggggccgagcgggtcggcga	Protospacer
.*  . ******.********* ****** *

470. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF919532 (Mycobacterium phage Sulley, complete genome) position: , mismatch: 8, identity: 0.742

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
acgccgggctcggggccgagcgggtcggcga	Protospacer
.*  . ******.********* ****** *

471. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_011984 (Agrobacterium vitis S4 plasmid pAtS4c, complete sequence) position: , mismatch: 8, identity: 0.75

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
atggcctggccgttcccgacgaacgaggttcg	Protospacer
.**.********** ********** * *.  

472. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 8, identity: 0.75

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
gggcgacggccgtagccgacgatcgcgttctc	Protospacer
* *   .****** ******** ******* *

473. spacer 28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 8, identity: 0.75

cggtgcgggttggcggtctatcggtgcggcta	CRISPR spacer
ctcgacgggttggcggtcgatcggtgtggaaa	Protospacer
*   .************* *******.**  *

474. spacer 28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 8, identity: 0.75

cggtgcgggttggcggtctatcggtgcggcta	CRISPR spacer
ctcgacgggttggcggtcgatcggtgtggaaa	Protospacer
*   .************* *******.**  *

475. spacer 28.3|4214558|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 8, identity: 0.75

cggtgcgggttggcggtctatcggtgcggcta	CRISPR spacer
ctcgacgggttggcggtcgatcggtgtggaaa	Protospacer
*   .************* *******.**  *

476. spacer 28.4|4214619|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 8, identity: 0.75

tgcgccgggtcggggaccacgtccacgtcgcc	CRISPR spacer
atcccggggtcggcgaccacgaccacgtcggt	Protospacer
  * * ******* ******* ******** .

477. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.758

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
ggcctcctgcttcagggtcgtgaacgcctgctc	Protospacer
**************.* *******  * *   *

478. spacer 30.1|4939798|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 8, identity: 0.765

tgcgatccctccccggtcggccgccgccgggcgc	CRISPR spacer
tccgcggcatccctggtcggccgccggcgggcgg	Protospacer
* **   * ****.************ ****** 

479. spacer 30.1|4939798|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

tgcgatccctccccggtcggccgccgccgggcgc	CRISPR spacer
atcggcccctccccggacggcccccgccggtagc	Protospacer
  **..********** ***** *******  **

480. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ggccttgagcacggccaggatcgcggtcacca	Protospacer
 .   .******************* .*****

481. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ggccttgagcacggccaggatcgcggtcacca	Protospacer
 .   .******************* .*****

482. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP035092 (Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gacgaagatcacggccaggatcgcgccgaaag	Protospacer
 * ** ** ****************** *  .

483. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_008688 (Paracoccus denitrificans PD1222 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gacgaagatcacggccaggatcgcgccgaaag	Protospacer
 * ** ** ****************** *  .

484. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gctgccgagcaccgcgaggatcgcgcccagga	Protospacer
   * ******* ** *************  *

485. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP017079 (Novosphingobium resinovorum strain SA1 plasmid pSA4, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgggccgagcagggccaggatcgcgatttccg	Protospacer
*.** ****** ************* .. **.

486. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_AP017660 (Sphingobium cloacae strain JCM 10874 plasmid pSCLO_6) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgggccgagcagggccaggatcgcgatttccg	Protospacer
*.** ****** ************* .. **.

487. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013073 (Sphingobium indicum B90A plasmid pSRL3, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgggccgagcagggccaggatcgcgatttccg	Protospacer
*.** ****** ************* .. **.

488. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP033968 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gtagacgagcaccgcgaggatcgcgcagacga	Protospacer
  .********* ** **********  ** *

489. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP037902 (Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gtagacgagcaccgcgaggatcgcgcagacga	Protospacer
  .********* ** **********  ** *

490. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP026546 (Cupriavidus metallidurans strain Ni-2 plasmid unnamed2) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gtagacgagcaccgcgaggatcgcgcagacga	Protospacer
  .********* ** **********  ** *

491. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP012703 (Sphingopyxis macrogoltabida strain EY-1 isolate activated sludge plasmid 3, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgggccgagcagggccaggatcgcgatttccg	Protospacer
*.** ****** ************* .. **.

492. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gcgcaccggcgcggccaggatcgcgccgaccg	Protospacer
  * ** .**.**************** ***.

493. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP005090 (Sphingobium sp. TKS plasmid pTK6, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgggccgagcagggccaggatcgcgatttccg	Protospacer
*.** ****** ************* .. **.

494. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_020544 (Sphingomonas sp. MM-1 plasmid pISP3, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgggccgagcagggccaggatcgcgatttccg	Protospacer
*.** ****** ************* .. **.

495. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP043439 (Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gtagacgagcaccgcgaggatcgcgcagacga	Protospacer
  .********* ** **********  ** *

496. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to MT108731 (Pseudomonas phage Epa43, complete genome) position: , mismatch: 8, identity: 0.75

caggac--gagcacggccaggatcgcgcccacca	CRISPR spacer
--ggtctggagcacggccaggatcacgctcagtg	Protospacer
  ** *  ****************.***.** ..

497. spacer 32.1|4969131|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035502 (Sphingosinicella sp. BN140058 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

tgacggaccgtctgacgtcagggcgtcggccc	CRISPR spacer
cgacggaccggctgacgtccgggccgcgaact	Protospacer
.********* ******** ****  **. *.

498. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 8, identity: 0.75

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
ggcacgccggtcatcgtcaccggcgcgctgtc	Protospacer
*** *** ***************.  ***   

499. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031081 (Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence) position: , mismatch: 8, identity: 0.75

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
cagttgcgggtcatcgtcaccgtgcggccgaa	Protospacer
 . *.*****************  ****. **

500. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031081 (Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence) position: , mismatch: 8, identity: 0.75

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
cagttgcgggtcatcgtcaccgtgcggccgaa	Protospacer
 . *.*****************  ****. **

501. spacer 32.2|4969192|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031083 (Paracoccus yeei strain CCUG 32053 plasmid pYEE5, complete sequence) position: , mismatch: 8, identity: 0.75

ggctcgcgggtcatcgtcaccggtcggctcaa	CRISPR spacer
cagttgcgggtcatcgtcaccgtgcggccgaa	Protospacer
 . *.*****************  ****. **

502. spacer 32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR536452 (Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 3) position: , mismatch: 8, identity: 0.75

gtccaccgccgccaatccagtcggccccgggg	CRISPR spacer
tgaaaccgccgccaatccagtcgtcgccgagc	Protospacer
    ******************* * ***.* 

503. spacer 32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 8, identity: 0.75

gtccaccgccgccaatccagtcggccccgggg	CRISPR spacer
gtgggccgccgccaagcctgtcggccccatga	Protospacer
**  .********** ** *********. *.

504. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 8, identity: 0.75

atcgtgcagcgtcgcccggccggcaacacggc-	CRISPR spacer
cacgcgcagcgtcgcccgcccggc-atgcagcc	Protospacer
  **.************* ***** *..*.** 

505. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

atcgtgcagcgtcgcccggccggcaacacggc-	CRISPR spacer
cacgcgcagcgtcgcccgcccggc-atgcagcc	Protospacer
  **.************* ***** *..*.** 

506. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.75

atcgtgcagcgtcgcccggccgg-caacacggc	CRISPR spacer
ctcgggcagcgccgcccggccggccgtcatga-	Protospacer
 *** ******.*********** *. **.*. 

507. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

atcgtgcagcgtcgcccggccggcaacacggc-	CRISPR spacer
cacgcgcagcgtcgcccgcccggc-atgcagcc	Protospacer
  **.************* ***** *..*.** 

508. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

atcgtgcagcgtcgcccggccggcaacacggc-	CRISPR spacer
cacgcgcagcgtcgcccgcccggc-atgcagcc	Protospacer
  **.************* ***** *..*.** 

509. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to MN096355 (Mycobacterium phage Purky, complete genome) position: , mismatch: 8, identity: 0.758

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cgccagcggtgtgctcggcgtcgccgcgcacga	Protospacer
*  *.***** ******.***********.*. 

510. spacer 33.5|4974314|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020927 (Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence) position: , mismatch: 8, identity: 0.758

tgtcggcgacgactgcgcccaggttgagcgcca	CRISPR spacer
gatcggcgtcgactgcgaccaggttggactcaa	Protospacer
 .****** ******** ********..* * *

511. spacer 33.5|4974314|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020927 (Sphingobium yanoikuyae strain SHJ plasmid pSES189, complete sequence) position: , mismatch: 8, identity: 0.758

tgtcggcgacgactgcgcccaggttgagcgcca	CRISPR spacer
gatcggcgtcgactgcgaccaggttggactcaa	Protospacer
 .****** ******** ********..* * *

512. spacer 33.7|4974438|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 8, identity: 0.758

cgcagccggcccggcggaggccaggccgatgat	CRISPR spacer
ggccagctgcccggcggaggtcaggccgaggag	Protospacer
 ** . * ************.******** ** 

513. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

514. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

515. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

516. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

517. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

518. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

519. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

520. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 8, identity: 0.765

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
cgctcgacgtcagcgttcaggccgacatcgtcga	Protospacer
.   * *** ***** *****************.

521. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
agcacgtccgcgacgtgggcctcgcgggagac	Protospacer
 * *.**********  ************ ..

522. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
agcacgtccgcgacgtgggcctcgcgggagac	Protospacer
 * *.**********  ************ ..

523. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
cgcctgtccgcgccggccgcctcgcgggcctg	Protospacer
**  ******** **** ********** .  

524. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
agcacgtccgcgacgtgggcctcgcgggagac	Protospacer
 * *.**********  ************ ..

525. spacer 35.2|4979082|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

ccgttcccggccggtgatcagcatgacggtca	CRISPR spacer
cactcggcggacggtggtcagcatgacggtcc	Protospacer
*  *.  *** *****.************** 

526. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 8, identity: 0.75

tggagc----ttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
----gcctcactcgaagaaaccgccgccgcactcga	Protospacer
    **    .****.*************** ***.

527. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 8, identity: 0.75

tggagcttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
atgggcgccgacgaaaccgccgccgccatcga	Protospacer
  *.** .*** ************** ****.

528. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

529. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

530. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

531. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029453 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

532. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP023069 (Ensifer sojae CCBAU 05684 plasmid pSJ05684a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

533. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_000914 (Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

534. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_000914 (Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

535. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NC_000914 (Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

536. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029233 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

537. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029233 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436a, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgacttgccggtgccggtgtggccggtgatga	Protospacer
   * ******** **************  * 

538. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021357 (Rhodococcus sp. S2-17 plasmid pRB11, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgcatcggcggtggcggtgtggccggcgaggt	Protospacer
  *  .* ******************.* ***

539. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021360 (Acidovorax carolinensis strain NA2 plasmid pACNA2.1, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gggcgtgccggtggcggtggtgccgggcgtgt	Protospacer
*  ****************  *****    **

540. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021367 (Acidovorax carolinensis strain P4 plasmid pACP4.1, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gggcgtgccggtggcggtggtgccgggcgtgt	Protospacer
*  ****************  *****    **

541. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021363 (Acidovorax carolinensis strain P3 plasmid pACP3.1, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gggcgtgccggtggcggtggtgccgggcgtgt	Protospacer
*  ****************  *****    **

542. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to MK059749 (Mycobacterium phage CRB2, complete genome) position: , mismatch: 8, identity: 0.75

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcagaggccggtggcggtgaggctggtgtcga	Protospacer
**  . ************* ***.***** * 

543. spacer 37.1|5319744|34|CP025990|PILER-CR matches to NC_023497 (Amycolatopsis keratiniphila plasmid pXL100, complete sequence) position: , mismatch: 8, identity: 0.765

acccggctacggcgacccgtcccag---cagggggcc	CRISPR spacer
ccccggctacggcgacccgaaccaggctcacgag---	Protospacer
 ******************  ****   ** *.*   

544. spacer 38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.778

ggggccggggcggcggcggtggcggtccggggcgtc	CRISPR spacer
gtctgcggggcgtcggcggtggtggtccggggcggg	Protospacer
*    ******* *********.***********  

545. spacer 38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN234225 (Mycobacterium phage Rhinoforte, complete genome) position: , mismatch: 8, identity: 0.778

ggggccggggcggcggcggtggcggtccggggcgtc----	CRISPR spacer
ggggcgggggcggtggcggtggcggt----ggtgttgaag	Protospacer
***** *******.************    **.**.    

546. spacer 38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to JF712866 (Vibrio phage phiVC8, complete genome) position: , mismatch: 8, identity: 0.778

ggggccggggcggcggcggtggcggtccggggcgtc	CRISPR spacer
ggtgtggcggcggcggcggtggcggttcgggtcgaa	Protospacer
** *. * ******************.**** **  

547. spacer 38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014801 (Rhodovulum sulfidophilum plasmid Plasmid1 DNA, complete genome, strain: DSM 2351) position: , mismatch: 8, identity: 0.778

ggggccggggcggcggcggtggcggtccggggcgtc----	CRISPR spacer
cggtccggggcggcggcggtcgcggtc----gcgccggat	Protospacer
 ** **************** ******    ***.*    

548. spacer 38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.778

--ggggccggggcggcggcggtggcggtccggggcgtc	CRISPR spacer
ccgaagc--gggcggcggcggtggcggtgctgggcctg	Protospacer
  *..**  ******************* * **** * 

549. spacer 39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016619 (Microvirga ossetica strain V5/3m plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ccctgcgcggccgccgtgtgccatgccaccgc	CRISPR spacer
gtgttcgcggccgccgtctgccaggccaccta	Protospacer
 . * ************ ***** ******  

550. spacer 39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP022268 (Xanthomonas citri pv. vignicola strain CFBP7112 plasmid plA, complete sequence) position: , mismatch: 8, identity: 0.75

ccctgcgcggccgccgtgtgccatgccaccgc	CRISPR spacer
ggccgcgcggccgccgcgtgccaagccgaccc	Protospacer
  *.************.****** ***. * *

551. spacer 39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP022268 (Xanthomonas citri pv. vignicola strain CFBP7112 plasmid plA, complete sequence) position: , mismatch: 8, identity: 0.75

ccctgcgcggccgccgtgtgccatgccaccgc	CRISPR spacer
ggccgcgcggccgccgcgtgccaagccgaccc	Protospacer
  *.************.****** ***. * *

552. spacer 39.1|5574090|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP022269 (Xanthomonas citri pv. vignicola strain CFBP7112 plasmid plB, complete sequence) position: , mismatch: 8, identity: 0.75

ccctgcgcggccgccgtgtgccatgccaccgc	CRISPR spacer
ggccgcgcggccgccgcgtgccaagccgaccc	Protospacer
  *.************.****** ***. * *

553. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
agcacgtccgcgacgtgggcctcgcgggagac	Protospacer
 * *.**********  ************ ..

554. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
agcacgtccgcgacgtgggcctcgcgggagac	Protospacer
 * *.**********  ************ ..

555. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
cgcctgtccgcgccggccgcctcgcgggcctg	Protospacer
**  ******** **** ********** .  

556. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.75

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
agcacgtccgcgacgtgggcctcgcgggagac	Protospacer
 * *.**********  ************ ..

557. spacer 39.9|5574578|31|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

cgctcatgagggatcgcgggaccgaggtcgg	CRISPR spacer
cttgcggaagcgatcgcggaaccgaggtcgg	Protospacer
* . *. .** ********.***********

558. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN317029 (Aeromonas phage vB_AhyS-A18P4, complete genome) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
cagtgcggcggcgtcctggcggcggcaatgggt	Protospacer
***.************ *********     *.

559. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
acgccatccggcgtcctggcggcggcccaccgc	Protospacer
  **    ******** ************.***

560. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tacgccggcggcgcgcaggcggcggcccaactc	Protospacer
.*   ********. ************** * *

561. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tacgccggcggcgcgcaggcggcggcccaactc	Protospacer
.*   ********. ************** * *

562. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gatgccggcggcgcgcaggcggcggcccagccc	Protospacer
 *   ********. ************** * *

563. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc-	CRISPR spacer
cagcgcggcggcgtcgcggcggc-gcttgcggcc	Protospacer
***************  ****** **.... ** 

564. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gatgccggcggcgcgcaggcggcggcccagccc	Protospacer
 *   ********. ************** * *

565. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gtgcatgacggcgtccagccggcggcccagcgt	Protospacer
  **..*.********** ********** **.

566. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 8, identity: 0.758

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ggcctctacggtcagcgtcggcgctgtcggcgc	Protospacer
* *  .. ***** ************.******

567. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 8, identity: 0.758

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ggcctcaacggtcagcgtcggcgctgtcggcgc	Protospacer
* *  .  ***** ************.******

568. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 8, identity: 0.758

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ggcctctacggtcagcgtcggcgctgtcggcgc	Protospacer
* *  .. ***** ************.******

569. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 8, identity: 0.758

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ggcctcaacggtcagcgtcggcgctgtcggcgc	Protospacer
* *  .  ***** ************.******

570. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.758

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
tcccctggcggtcgccgtcggcgctgccggcga	Protospacer
 **  *  *****  ***************** 

571. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024940 (Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence) position: , mismatch: 8, identity: 0.758

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
gtccgcaccggtctgcgtctgcgttgccggccg	Protospacer
*.* *. ************ ***.*******  

572. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP021083 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI2, complete sequence) position: , mismatch: 8, identity: 0.765

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
gcacccggacgcccggggcgtgatccgctcacac	Protospacer
   ** ********.***************  .*

573. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to KU310943 (Pseudomonas phage YMC11/07/P54_PAE_BP, complete genome) position: , mismatch: 8, identity: 0.765

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
cgctggccatgcccagggcgtgcgccgctccggc	Protospacer
**.. *  *.************  **********

574. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP029174 (Methylobacterium sp. DM1 plasmid pLVM1, complete sequence) position: , mismatch: 8, identity: 0.75

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gttgctcgacgccgagggcgtgatccgcgcca	Protospacer
  * *  ****** ************** **.

575. spacer 43.5|6196115|33|CP025990|CRISPRCasFinder,CRT matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 8, identity: 0.758

gctgcgcccgcgccgcacgccggtccgccggag	CRISPR spacer
gcgcagcccgcgccccacgccggcccgcccgca	Protospacer
**   ********* ********.***** * .

576. spacer 43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 8, identity: 0.758

ccctggccccggtccgccgccgcctgatcgccc	CRISPR spacer
accaattgccggtccgccgccgccagatcgccg	Protospacer
 ** . . **************** ******* 

577. spacer 43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ccctggccccggtccgccgccgcctgatcgccc	CRISPR spacer
ccctcgccccggtccgcctccgcccggcggtac	Protospacer
**** ************* *****.*.. *. *

578. spacer 43.10|6196420|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_015851 (Acidithiobacillus caldus SM-1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.758

cgcatccagcaggcccgtgacctcacccgaccc	CRISPR spacer
cgcatccaacaggcccttgacctcgcatccgcc	Protospacer
********.******* *******.* .   **

579. spacer 44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 8, identity: 0.758

cggcagcttcgacaggacgttgttccggaccca	CRISPR spacer
gggcagcttcggcaagacgttgttcccggggct	Protospacer
 **********.**.*********** *.  * 

580. spacer 44.6|6577596|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 8, identity: 0.758

cggcagcttcgacaggacgttgttccggaccca	CRISPR spacer
gggcagcttcggcaagacgttgttcccggggct	Protospacer
 **********.**.*********** *.  * 

581. spacer 47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP010727 (Phaeobacter inhibens strain P88 plasmid pP88_b, complete sequence) position: , mismatch: 8, identity: 0.765

ccgagctcagcgcccgcacgcgccgataaccagg----	CRISPR spacer
gcgagctcagcgcccgcctgcgccg----cctggagca	Protospacer
 **************** .******    ** **    

582. spacer 47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP010611 (Phaeobacter inhibens strain P92 plasmid pP92_a, complete sequence) position: , mismatch: 8, identity: 0.765

ccgagctcagcgcccgcacgcgccgataaccagg----	CRISPR spacer
gcgagctcagcgcccgcctgcgccg----cctggagca	Protospacer
 **************** .******    ** **    

583. spacer 47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP010716 (Phaeobacter piscinae strain P18 plasmid pP18_a, complete sequence) position: , mismatch: 8, identity: 0.765

ccgagctcagcgcccgcacgcgccgataaccagg----	CRISPR spacer
gcgagctcagcgcccgcctgcgccg----cctggagca	Protospacer
 **************** .******    ** **    

584. spacer 47.20|6791494|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP010662 (Phaeobacter inhibens strain P74 plasmid pP74_a, complete sequence) position: , mismatch: 8, identity: 0.765

ccgagctcagcgcccgcacgcgccgataaccagg----	CRISPR spacer
gcgagctcagcgcccgcctgcgccg----cctggagca	Protospacer
 **************** .******    ** **    

585. spacer 47.22|6791643|38|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 8, identity: 0.789

tgcgcgtgacggacatcgccggcggcctcctggagctg---	CRISPR spacer
tgcgcgtggcggacatcgccggcg---ccctggtgcgcaac	Protospacer
********.***************   .***** **     

586. spacer 47.22|6791643|38|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.789

tgcgcgtgacggacatcgccggcggcctcctggagctg---	CRISPR spacer
tgcgcgtggcggacatcgccggcg---ccctggtgcgcaac	Protospacer
********.***************   .***** **     

587. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

588. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

589. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

590. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

591. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

592. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

593. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

594. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

595. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

596. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

597. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

598. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

599. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

600. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gaccgcctgggccgcaagctgacctacgccat	Protospacer
* **   .** ** *****************.

601. spacer 1.3|123743|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_JX627580 (Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence) position: , mismatch: 9, identity: 0.727

cggcccttgcccatgacccggatcgtcccggtg	CRISPR spacer
cggccctttccgatgacccggatctggccctcc	Protospacer
******** ** ************   **  . 

602. spacer 1.3|123743|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015368 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence) position: , mismatch: 9, identity: 0.727

cggcccttgcccatgacccggatcgtcccggtg	CRISPR spacer
cggccctttccgatgacccggatctggccctcc	Protospacer
******** ** ************   **  . 

603. spacer 4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_007353 (Sphingomonas sp. A1 plasmid pA1 DNA, complete sequence) position: , mismatch: 9, identity: 0.727

tcgccgccgccgctggcccggacggccggtggc	CRISPR spacer
gcgccgccggcgctggcccggtcggcatcgagg	Protospacer
 ******** *********** ****    .* 

604. spacer 4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 9, identity: 0.727

tcgccgccgccgctggcccggacggccggtggc	CRISPR spacer
tcgccgccgccgcaggccaggacgagcacccgg	Protospacer
************* **** *****. *. . * 

605. spacer 4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_MN366361 (Bacterium plasmid pALTS33, complete sequence) position: , mismatch: 9, identity: 0.727

tcgccgccgccgctggcccggacggccggtggc	CRISPR spacer
gcgccgccggcgctggcccggtcggcatcgagg	Protospacer
 ******** *********** ****    .* 

606. spacer 4.2|207496|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_019369 (Burkholderia cepacia plasmid pYS1, complete sequence) position: , mismatch: 9, identity: 0.727

tcgccgccgccgctggcccggacggccggtggc	CRISPR spacer
gcgccgccggcgctggcccggtcggcatcgagg	Protospacer
 ******** *********** ****    .* 

607. spacer 4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021360 (Acidovorax carolinensis strain NA2 plasmid pACNA2.1, complete sequence) position: , mismatch: 9, identity: 0.735

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
cccgccgcgccgagctgaccgcccgcctcaccaa	Protospacer
.****** *********.*******.*. * . *

608. spacer 4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021367 (Acidovorax carolinensis strain P4 plasmid pACP4.1, complete sequence) position: , mismatch: 9, identity: 0.735

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
cccgccgcgccgagctgaccgcccgcctcaccaa	Protospacer
.****** *********.*******.*. * . *

609. spacer 4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021363 (Acidovorax carolinensis strain P3 plasmid pACP3.1, complete sequence) position: , mismatch: 9, identity: 0.735

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
cccgccgcgccgagctgaccgcccgcctcaccaa	Protospacer
.****** *********.*******.*. * . *

610. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to MN234206 (Arthrobacter phage Racecar, complete genome) position: , mismatch: 9, identity: 0.727

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
tgcgccatcgaccgccagccgcaggattacatc	Protospacer
  *************** * ******. . *.*

611. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to MN234211 (Arthrobacter phage Mimi, complete genome) position: , mismatch: 9, identity: 0.727

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
tgcgccatcgaccgccagccgcaggattacatc	Protospacer
  *************** * ******. . *.*

612. spacer 4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021360 (Acidovorax carolinensis strain NA2 plasmid pACNA2.1, complete sequence) position: , mismatch: 9, identity: 0.735

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
cccgccgcgccgagctgaccgcccgcctcaccaa	Protospacer
.****** *********.*******.*. * . *

613. spacer 4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021367 (Acidovorax carolinensis strain P4 plasmid pACP4.1, complete sequence) position: , mismatch: 9, identity: 0.735

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
cccgccgcgccgagctgaccgcccgcctcaccaa	Protospacer
.****** *********.*******.*. * . *

614. spacer 4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021363 (Acidovorax carolinensis strain P3 plasmid pACP3.1, complete sequence) position: , mismatch: 9, identity: 0.735

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
cccgccgcgccgagctgaccgcccgcctcaccaa	Protospacer
.****** *********.*******.*. * . *

615. spacer 4.8|207864|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 9, identity: 0.727

gaccggctccagagtgcggcccgtcgcagcgaa	CRISPR spacer
gtccggcaccagcgtgcggcccgtcgggtccgg	Protospacer
* ***** **** ************* . * ..

616. spacer 4.8|207864|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

gaccggctccagagtgcggcccgtcgcagcgaa	CRISPR spacer
cagcggctccagcgtgcggcccatcgccttgcg	Protospacer
 * ********* *********.****  .* .

617. spacer 4.9|207925|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP053858 (Rhizobium pusense strain 76 plasmid pR76, complete sequence) position: , mismatch: 9, identity: 0.735

cgaccgtgctctccgacgaaccggacccggaccc	CRISPR spacer
tcgccgtgctccctgacgaaccggaccggccccg	Protospacer
. .********.*.************* *  ** 

618. spacer 4.12|208109|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.727

ggccgcatccggatcgtgctggtcggcgggtcc	CRISPR spacer
acgcgcatccggctcgtgccggtcggcgaggtg	Protospacer
.  ********* ******.********.* . 

619. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 9, identity: 0.743

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
acgacggcgcgcaccgcggcgagcgcggccgccgg	Protospacer
    ******************** ****   *.*

620. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH727545 (Mycobacterium phage DismalStressor, complete genome) position: , mismatch: 9, identity: 0.743

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
caccgcttgagcaccgcggcggcctcggcgcgcag	Protospacer
*.*.   .* ***********. ************

621. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_026598 (Mycobacterium phage Milly, complete genome) position: , mismatch: 9, identity: 0.743

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
caccgcttgagcaccgcggcggcctcggcgcgcag	Protospacer
*.*.   .* ***********. ************

622. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KX688047 (Mycobacterium phage Marcoliusprime, complete genome) position: , mismatch: 9, identity: 0.743

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
caccgcttgagcaccgcggcggcctcggcgcgcag	Protospacer
*.*.   .* ***********. ************

623. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MF140408 (Mycobacterium phage DismalFunk, complete genome) position: , mismatch: 9, identity: 0.743

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
caccgcttgagcaccgcggcggcctcggcgcgcag	Protospacer
*.*.   .* ***********. ************

624. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MF140411 (Mycobacterium phage Findley, complete genome) position: , mismatch: 9, identity: 0.743

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
caccgcttgagcaccgcggcggcctcggcgcgcag	Protospacer
*.*.   .* ***********. ************

625. spacer 6.12|408965|35|CP025990|CRISPRCasFinder,CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 9, identity: 0.743

tcctgcgcgtcccgcgcgtccggcgtcagcgccac	CRISPR spacer
atcatcgcgtcgcgcgcgtccggcggcagcgcttt	Protospacer
 .*  ****** ************* ******. .

626. spacer 6.12|408965|35|CP025990|CRISPRCasFinder,CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 9, identity: 0.743

tcctgcgcgtcccgcgcgtccggcgtcagcgccac	CRISPR spacer
atcatcgcgtcgcgcgcgtccggcggcagcgcttt	Protospacer
 .*  ****** ************* ******. .

627. spacer 6.12|408965|35|CP025990|CRISPRCasFinder,CRT matches to NC_010847 (Paracoccus aminophilus strain JCM 7686 plasmid pAMI2, complete sequence) position: , mismatch: 9, identity: 0.743

tcctgcgcgtcccgcgcgtccggcgtcagcgccac	CRISPR spacer
gcgctggcgtgccgcgcgttcggcgtcagcgagac	Protospacer
 * .  **** ********.***********  **

628. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 9, identity: 0.719

gacaacggccgcgcggccagctcgacaaaccc	CRISPR spacer
ccgtccggccgcgcggccaccgcgacaaagca	Protospacer
     ************** * ******* * 

629. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP009453 (Sphingopyxis sp. 113P3 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gacaacggccgcgcggccagctcgacaaaccc	CRISPR spacer
agcgtcggccgcgcggccagatcgccaagggc	Protospacer
..*. *************** *** ***.  *

630. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP021029 (Rhizobium sp. TAL182 plasmid pRetTAL182e, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

631. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013600 (Rhizobium sp. N741 plasmid pRspN741e, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

632. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013504 (Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

633. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013510 (Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

634. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013521 (Rhizobium sp. N113 plasmid pRspN113d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

635. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013494 (Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

636. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013515 (Rhizobium sp. N1314 plasmid pRspN1314d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

637. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013594 (Rhizobium sp. N871 plasmid pRspN871d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

638. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP013605 (Rhizobium sp. N731 plasmid pRspN731d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgatgtcaccgatcccgagccgctgccatcg	Protospacer
 **** ************ ******* ..   

639. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP019608 (Tessaracoccus flavescens strain SST-39T plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
gcgatctcacggatcccgcgacgcccggaatc	Protospacer
********** ********* ***. * .. .

640. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP006990 (Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgctctcaccgattccgcgccgctcatcatc	Protospacer
 ** **********.********** .* . .

641. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgctctcaccgattccgcgccgctcatcatc	Protospacer
 ** **********.********** .* . .

642. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcgctctcaccgattccgcgccgctcatcatc	Protospacer
 ** **********.********** .* . .

643. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NZ_CP050095 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b1, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcaaggatgccgatcacgcgccgctgatggat	Protospacer
 *.*   ..****** **********.*****

644. spacer 8.3|478807|32|CP025990|CRISPRCasFinder matches to NC_008381 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcaccgatcccgcgccgctggtggat	CRISPR spacer
tcaaggatgccgatcacgcgccgctgatggat	Protospacer
 *.*   ..****** **********.*****

645. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 9, identity: 0.719

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
aagacccggacccggtcgtcctcgaactgggc	Protospacer
. * ******* *** ************    

646. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 9, identity: 0.719

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
aagacccggacccggtcgtcctcgaactgggc	Protospacer
. * ******* *** ************    

647. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 9, identity: 0.719

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
aagacccggacccggtcgtcctcgaactgggc	Protospacer
. * ******* *** ************    

648. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatggtcgtcggcgggctgtggc	Protospacer
 ****************.******   .. * 

649. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
tgcggcggtgatggtcgccagcgggctgcgca	Protospacer
****** ************.****   .*  .

650. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP046575 (Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
tgcggcggtgatggtcgccagcgggctgcgca	Protospacer
****** ************.****   .*  .

651. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP049358 (Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggtggccgtgctggtcgccgacggtgtggacg	Protospacer
 *.******* *********.***** .   *

652. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP011044 (Clavibacter michiganensis subsp. insidiosus strain R1-1 plasmid pCI1, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcgtgc	Protospacer
 ***********  **********     ** 

653. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP021035 (Clavibacter michiganensis subsp. insidiosus strain R1-3 plasmid pCI1, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcgtgc	Protospacer
 ***********  **********     ** 

654. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP021039 (Clavibacter michiganensis subsp. insidiosus strain ATCC 10253 plasmid pCI1, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgatcctcgccggcgggctcgtgc	Protospacer
 ***********  **********     ** 

655. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
cgcggacgtgatggtcgccggtggcaccgagg	Protospacer
.**** ***************.**..    **

656. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP031159 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence) position: , mismatch: 9, identity: 0.719

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggtggccgtgctggtcgccgacggtgtggacg	Protospacer
 *.******* *********.***** .   *

657. spacer 8.7|478685|33|CP025990|PILER-CR,CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

gacaacggccgcgcggccagctcgacaaacccc	CRISPR spacer
ttgttcagccgcgcggccagctcgacataaccg	Protospacer
     *.******************** * ** 

658. spacer 8.7|478685|33|CP025990|PILER-CR,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 9, identity: 0.727

gacaacggccgcgcggccagctcgacaaacccc	CRISPR spacer
ccgtccggccgcgcggccaccgcgacaaagcac	Protospacer
     ************** * ******* * *

659. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatctcaccgatcccgcgccgctggtggatc	CRISPR spacer
gcgatctcacggatcccgcgctgctccgaggcg	Protospacer
********** **********.***   .*.. 

660. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NC_012854 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatctcaccgatcccgcgccgctggtggatc	CRISPR spacer
tcgctctcaccgattccgcgccgctgatcatcg	Protospacer
 ** **********.***********.* . . 

661. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP019608 (Tessaracoccus flavescens strain SST-39T plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatctcaccgatcccgcgccgctggtggatc	CRISPR spacer
gcgatctcacggatcccgcgacgcccggaatcc	Protospacer
********** ********* ***. * .. .*

662. spacer 9.16|482147|32|CP025990|CRT matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cgtggtcggacgtggtgtcgatcggcatgctt	CRISPR spacer
tgaaggtcgacgtgctgtcgctcggcatgctg	Protospacer
.* .* . ****** ***** ********** 

663. spacer 10.1|554801|33|CP025990|CRT matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 9, identity: 0.727

--atcatcggcctggcctccgccggcccggctgcg	CRISPR spacer
gcgccgctg--ctggtctccgccagcccggctgcg	Protospacer
  ..*...*  ****.*******.***********

664. spacer 10.1|554801|33|CP025990|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 9, identity: 0.727

--atcatcggcctggcctccgccggcccggctgcg	CRISPR spacer
gcgccgctg--ctggtctccgccagcccggctgcg	Protospacer
  ..*...*  ****.*******.***********

665. spacer 10.1|554801|33|CP025990|CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 9, identity: 0.727

--atcatcggcctggcctccgccggcccggctgcg	CRISPR spacer
gcgccgctg--ctggtctccgccagcccggctgcg	Protospacer
  ..*...*  ****.*******.***********

666. spacer 10.1|554801|33|CP025990|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.727

atcatcggcctggcctccgccggcccggctgcg	CRISPR spacer
gtcatcgtcctggcctcggccggccagatagtc	Protospacer
.****** ********* ******* *.. *. 

667. spacer 10.1|554801|33|CP025990|CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 9, identity: 0.727

--atcatcggcctggcctccgccggcccggctgcg	CRISPR spacer
gcgccgctg--ctggtctccgccagcccggctgcg	Protospacer
  ..*...*  ****.*******.***********

668. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
atccgggtcgcccggcccggcgccgaccagccag	Protospacer
 *.    * ********.* **************

669. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
gccgccctggcccgggccgccgccgactacgcac	Protospacer
 ..************ *.*********.*  ** 

670. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to LN997844 (Streptomyces reticuli genome assembly TUE45, plasmid : III) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gagaacctggcccggcaggccgccgaccatggca-	Protospacer
   . ***********  *********** * ** 

671. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to LN997844 (Streptomyces reticuli genome assembly TUE45, plasmid : III) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gagaacctggcccggcaggccgccgaccatggca-	Protospacer
   . ***********  *********** * ** 

672. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to LN997844 (Streptomyces reticuli genome assembly TUE45, plasmid : III) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gagaacctggcccggcaggccgccgaccatggca-	Protospacer
   . ***********  *********** * ** 

673. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to LN997844 (Streptomyces reticuli genome assembly TUE45, plasmid : III) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgacca-gccag	CRISPR spacer
gagaacctggcccggcaggccgccgaccatggca-	Protospacer
   . ***********  *********** * ** 

674. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to LN997844 (Streptomyces reticuli genome assembly TUE45, plasmid : III) position: , mismatch: 9, identity: 0.735

tttgccctggcccggcctgccgccgaccagccag--	CRISPR spacer
gagaacctggcccggcaggccgccgacca--cagca	Protospacer
   . ***********  ***********  ***  

675. spacer 10.9|555291|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 9, identity: 0.727

cattggtttcggaccgggcagcccgcgcagatc	CRISPR spacer
aagcgcgcccggaccggtcagcccgctcagatc	Protospacer
 * .*  ..******** ******** ******

676. spacer 13.4|792104|35|CP025990|PILER-CR,CRT matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 9, identity: 0.743

caccgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
tgccgcctcgccctcaccgacctcgaccgccaggg	Protospacer
..**** ************** *****  **  * 

677. spacer 13.17|792105|34|CP025990|CRISPRCasFinder matches to NZ_LR134457 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 15, complete sequence) position: , mismatch: 9, identity: 0.735

accgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
cgctcggcttcctcgccgacaacgacgccctcgc	Protospacer
  * *. * .****.****** ************

678. spacer 13.17|792105|34|CP025990|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 9, identity: 0.735

accgcatcgccctcaccgacatcgacgccctcgc	CRISPR spacer
ttggcgacaccctgaccgacctcgacgccctcgt	Protospacer
 . **. *.**** ****** ************.

679. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020040 (Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
ttgtggtagagcccgaccacgtcgacgaccttcgc	Protospacer
*. *   . *** **** *****************

680. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MT723937 (Gordonia phage JKSyngboy, complete genome) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
aacgcgagcggcgcggcgacgtcgacgacctcgac	Protospacer
  * * ***.*****.***************. .*

681. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH450129 (Gordonia phage Ribeye, complete genome) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
aacgcgagcggcgcggcgacgtcgacgacctcgac	Protospacer
  * * ***.*****.***************. .*

682. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH976509 (Gordonia phage Bizzy, complete genome) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
aacgcgagcggcgcggcgacgtcgacgacctcgac	Protospacer
  * * ***.*****.***************. .*

683. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH651168 (Gordonia phage Ashertheman, complete genome) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
aacgcgagcggcgcggcgacgtcgacgacctcgac	Protospacer
  * * ***.*****.***************. .*

684. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH976513 (Gordonia phage Kroos, complete genome) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
aacgcgagcggcgcggcgacgtcgacgacctcgac	Protospacer
  * * ***.*****.***************. .*

685. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MK967396 (Gordonia phage Tangerine, complete genome) position: , mismatch: 9, identity: 0.743

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
aacgcgagcggcgcggcgacgtcgacgacctcgac	Protospacer
  * * ***.*****.***************. .*

686. spacer 14.2|1142214|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH271303 (Microbacterium phage MementoMori, complete genome) position: , mismatch: 9, identity: 0.75

-----ccgagagggaggccaaggacgccgagaacgccgcga	CRISPR spacer
tgacccc-----ggaggccacggacgcggagaacgccgcag	Protospacer
     **     ******** ****** ***********..

687. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 9, identity: 0.75

gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
tcgtcggcctggcgcagcagcgccggcaggttggcg	Protospacer
 .*.***** *********************.    

688. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 9, identity: 0.75

gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
acgccggcccggcgcagcagcaccggcagggcttcg	Protospacer
..******* ***********.******** *..  

689. spacer 18.2|2981929|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016620 (Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

gatgccctcgacatcggtcggcgtctcccctt	CRISPR spacer
gatgccctccacaccggtcggcggtgtcgtct	Protospacer
********* ***.********* . .* ..*

690. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009975 (Pseudomonas putida S12 plasmid pTTS12, complete sequence) position: , mismatch: 9, identity: 0.719

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
ggcgtgatgccggaaatcgcctggctggatga	Protospacer
 ******** ****.**********. . *. 

691. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 9, identity: 0.719

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
tgcgtgatggtggagatcacctgcggcaggcc	Protospacer
**********.*******.****   **   .

692. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to NC_007762 (Rhizobium etli CFN 42 plasmid p42a, complete sequence) position: , mismatch: 9, identity: 0.719

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
ccgccacctgccgggcgcttccggcgggcaag	Protospacer
************** *** ****     *  *

693. spacer 19.4|3490862|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034352 (Streptomyces sp. W1SF4 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.743

cccctccccgccgtcctcgtcggactcgggctcgc	CRISPR spacer
ggcctctccgccgtcctcgtcggactcatggcggg	Protospacer
  ****.********************. * . * 

694. spacer 19.4|3490862|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_011366 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence) position: , mismatch: 9, identity: 0.743

cccctccccgccgtcctcgtcggactcgggctcgc	CRISPR spacer
ctcatccccgccctcctcgtcggtctcggccggaa	Protospacer
*.* ******** ********** ***** *  . 

695. spacer 22.9|3492088|34|CP025990|CRT matches to MG065691 (UNVERIFIED: Campylobacter phage A11a, complete genome) position: , mismatch: 9, identity: 0.735

agcctgtatgacctgctcgccgccaagaacggat	CRISPR spacer
tgcccaggtgaccagcacgccgccaagaacgggg	Protospacer
 ***.. .***** ** ***************. 

696. spacer 22.9|3492088|34|CP025990|CRT matches to MG065686 (UNVERIFIED: Campylobacter phage A18a, complete genome) position: , mismatch: 9, identity: 0.735

agcctgtatgacctgctcgccgccaagaacggat	CRISPR spacer
tgcccaggtgaccagcacgccgccaagaacgggg	Protospacer
 ***.. .***** ** ***************. 

697. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 9, identity: 0.727

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
gggcagcgcctgggacatcgccgcggcgtcggt	Protospacer
    * **** **************.**** *.

698. spacer 22.13|3492357|33|CP025990|CRT matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.727

tccgatcgccggggacatcgccgcgacgtccgc	CRISPR spacer
cgcggcggccggggagatggccgcgacgtccat	Protospacer
. **.. ******** ** ************..

699. spacer 22.14|3492423|31|CP025990|CRT matches to NZ_CP013917 (Sphingomonas sp. LK11 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.71

aaccggtcatcgtcggggcctacgaggacac	CRISPR spacer
atgtcatcatcgtcgtggcctacgacgacga	Protospacer
*  . .********* ********* ***. 

700. spacer 24.2|3572256|32|CP025990|PILER-CR matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tagccgggtgaatcccgctcggcgggcggcgc	CRISPR spacer
agatcgtccgaatcacgctcggcaggcggcgc	Protospacer
 ...**  .***** ********.********

701. spacer 24.4|3572378|32|CP025990|PILER-CR matches to CP052219 (Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-2, complete sequence) position: , mismatch: 9, identity: 0.719

gaggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
agcgcacttgacgcgcgcaaccgacgcgtagc	Protospacer
.. * ***** ************** **  * 

702. spacer 24.4|3572378|32|CP025990|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.719

gaggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
gaggaactcgtcgggcgcaaccggcgccagat	Protospacer
********.**** *********.* * . . 

703. spacer 24.4|3572378|32|CP025990|PILER-CR matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 9, identity: 0.719

gaggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
gcccagagtggcgcgtgcaaccgacccggtgc	Protospacer
*   *.  ** ****.*************** 

704. spacer 24.4|3572378|32|CP025990|PILER-CR matches to NZ_CP024642 (Klebsiella michiganensis strain F107 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gaggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
agcgcacttgacgcgcgcaaccgacgcgtagc	Protospacer
.. * ***** ************** **  * 

705. spacer 24.5|3572196|31|CP025990|CRISPRCasFinder matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

ggtgcggccggtcggacctgacggcgctccg	CRISPR spacer
gacgcggccggtcggctctgacggcggggtc	Protospacer
*..************ .*********   . 

706. spacer 24.8|3572379|31|CP025990|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 9, identity: 0.71

aggaacttgtcgcgcgcaaccgacccggtgg	CRISPR spacer
cccagagtggcgcgtgcaaccgacccggtgc	Protospacer
   *.  ** ****.*************** 

707. spacer 25.7|3609657|31|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_047861 (Bordetella phage vB_BbrM_PHB04, complete genome) position: , mismatch: 9, identity: 0.71

tccgttctcacccagcggcggcgtcgtcgtc	CRISPR spacer
cgagttgtcgcccagcggcggcgtcggagcg	Protospacer
.  *** **.****************  *. 

708. spacer 27.1|3802758|33|CP025990|CRISPRCasFinder matches to NZ_CP033968 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

cagcccccggccggctaccagccgccacccggg	CRISPR spacer
gtacgtacggccgcctgccagccgccacccgcg	Protospacer
  .* . ****** **.************** *

709. spacer 27.1|3802758|33|CP025990|CRISPRCasFinder matches to NZ_CP043439 (Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.727

cagcccccggccggctaccagccgccacccggg	CRISPR spacer
ttacgtacggccgcctgccagccgccacccgcg	Protospacer
. .* . ****** **.************** *

710. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_KY494864 (Pseudomonas aeruginosa strain FFUP_PS_37 plasmid pJB37, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

711. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_KU130294 (Pseudomonas putida strain 12969 plasmid p12969-DIM, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

712. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP009975 (Pseudomonas putida S12 plasmid pTTS12, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

713. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP039989 (Pseudomonas aeruginosa strain T2436 plasmid pBT2436, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

714. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP039991 (Pseudomonas aeruginosa strain T2101 plasmid pBT2101, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

715. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
ggggacgggtcgaggccgtgcgtgtcgggcc	Protospacer
*  . *** ********* ********* . 

716. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_MN433457 (Pseudomonas aeruginosa strain PAB546 plasmid pNK546-KPC, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

717. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP045003 (Pseudomonas aeruginosa strain PAG5 plasmid pPAG5, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

718. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP045917 (Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

719. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF344571 (Pseudomonas aeruginosa plasmid pR31014-IMP, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

720. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF344568 (Pseudomonas aeruginosa plasmid p727-IMP, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

721. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF344569 (Pseudomonas aeruginosa plasmid p12939-PER, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

722. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to MF344570 (Pseudomonas aeruginosa plasmid pA681-IMP, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

723. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
tccaccgggtcgaggccgagcgtgctgatgg	Protospacer
 ***.*** ***************..*.. .

724. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP040126 (Pseudomonas aeruginosa strain PA298 plasmid pBM908, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

725. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_CP016215 (Pseudomonas aeruginosa strain PA121617 plasmid pBM413, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

726. spacer 28.1|4214437|31|CP025990|CRISPRCasFinder,CRT matches to NZ_KY883660 (Pseudomonas putida strain SY153 plasmid pSY153-MDR, complete sequence) position: , mismatch: 9, identity: 0.71

gccatcggctcgaggccgagcgtgtcggcta	CRISPR spacer
gatcgcggctcgaggctgagcgtggcggtct	Protospacer
* .  ***********.******* ***.. 

727. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 9, identity: 0.719

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
atgacctggccggtgccgccgaacagcagcag	Protospacer
.*********** ***** *****.    ** 

728. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MG018928 (Pseudomonas phage inbricus, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
cccgcttggcttcaagttcgtgaactcggtggc	Protospacer
  * ... **************** *** ****

729. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MK962632 (Achromobacter phage vB_AxyP_19-32_Axy13, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
cccgcttggcttcaagttcgtgaactcggtggc	Protospacer
  * ... **************** *** ****

730. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MK962641 (Achromobacter phage vB_AxyP_19-32_Axy24, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
tgaacgcaacttcaagttcgtgaactcggtggc	Protospacer
 *  . * .*************** *** ****

731. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MK962626 (Achromobacter phage vB_AxyP_19-32_Axy04, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
tgaacgcaacttcaagttcgtgaactcggtggc	Protospacer
 *  . * .*************** *** ****

732. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MK867354 (Synechococcus phage S-SCSM1, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
gtgctcctgcttcaagtttttgaagtcttgctt	Protospacer
*  ***************. ******* *   .

733. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MK962631 (Achromobacter phage vB_AxyP_19-32_Axy12, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
tgaacgcaacttcaagttcgtgaactcggtggc	Protospacer
 *  . * .*************** *** ****

734. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to KT321317 (Achromobacter phage phiAxp-3, complete genome) position: , mismatch: 9, identity: 0.727

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
tgaacgcaacttcaagttcgtgaactcggtggc	Protospacer
 *  . * .*************** *** ****

735. spacer 30.1|4939798|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.735

tgcgatccctccccggtcggccgccgccgggcgc	CRISPR spacer
gacctcctcgccccggtcgaccgccgcctggcgc	Protospacer
 .*  .*.* *********.******** *****

736. spacer 30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020441 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

gtggcgctggaccgggtcgaggcggctcggcccct	CRISPR spacer
gtggcgctggagcgggtcgcggcggtagagcacaa	Protospacer
*********** ******* *****.  .** *  

737. spacer 30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020447 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed7, complete sequence) position: , mismatch: 9, identity: 0.743

gtggcgctggaccgggtcgaggcggctcggcccct	CRISPR spacer
gtggcgctggagcgggtcgcggcggtagagcacaa	Protospacer
*********** ******* *****.  .** *  

738. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
caggaggagcacgcccaggatcgcgaagttgc	Protospacer
***** ******* ***********    .  

739. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ggccttcagcacggccagcatcgcgaccacca	Protospacer
 .   . *********** ****** ******

740. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gtcgacgagcgcggccagggtcgcgccggcgc	Protospacer
   *******.********.******* .*  

741. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gaggacgagcgcggccaggagcgcgaggcgcg	Protospacer
 *********.********* ****     *.

742. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP039924 (Agrobacterium tumefaciens strain CFBP7129 plasmid pAtCFBP7129a, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
gtagacgagcaccgtcaggatcgcgccggaga	Protospacer
  .********* *.************ .  *

743. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
caggccgagcacggtcaggatcgggatgagag	Protospacer
**** *********.******** * . *  .

744. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
catcgttgccacggccaggagcgcgcccagca	Protospacer
**  .. . *********** ******** **

745. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
cgacatcggcacggccgagatcgcgcccaccg	Protospacer
*.. *. .********..*************.

746. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP023065 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence) position: , mismatch: 9, identity: 0.719

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ctcaacgagcacggccaggatcttgcctcacg	Protospacer
*  .****************** .***.  *.

747. spacer 32.1|4969131|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tgacggaccgtctgacgtcagggcgtcggccc	CRISPR spacer
cggcggacggcctgacgtcagggcgtttgagg	Protospacer
.*.***** *.***************. *   

748. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to JX100810 (Caulobacter phage CcrColossus, complete genome) position: , mismatch: 9, identity: 0.719

atcgtgcagcgtcgcccggccggcaacacggc	CRISPR spacer
ggctcgcagcgtatcccggccggcaacaccaa	Protospacer
. * .*******  *************** . 

749. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020385 (Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence) position: , mismatch: 9, identity: 0.719

atcgtgcagcgtcgcccggccggcaacacggc	CRISPR spacer
atcgagcagcgacgcccggccggagacctcct	Protospacer
**** ****** *********** .** .  .

750. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cgggcacggtctgctcgacggcggcgcgcggca	Protospacer
* *  .************** ** ******   

751. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
gcgcggcggtcatctcgacgtcgccatcctcgg	Protospacer
 **********  ************.. * *. 

752. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NC_015409 (Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
ggtcggcgggctgctcgacctcgccgcccccgg	Protospacer
   ****** ********* ******* * *. 

753. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to LT999987 (Pseudomonas phage vB_PaeS_PAO1_HW12 genome assembly, complete genome: monopartite) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcgatctgctcgacgtcggcgtccttgg	Protospacer
* ******.************** **. * .. 

754. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to KM389460 (UNVERIFIED: Pseudomonas phage F_MX560sp/Pa1651 clone contig00001 genomic sequence) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcgatctgctcgacgtcggcgtccttgg	Protospacer
* ******.************** **. * .. 

755. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to EU744250 (Mycobacterium virus Pukovnik, complete genome) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcggtctggtcgacctcgccggtaaggc	Protospacer
* *********** ***** ******   . .*

756. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to KM389278 (UNVERIFIED: Pseudomonas phage Phi05_1400 B clone contig00006 genomic sequence) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcgatctgctcgacgtcggcgtccttgg	Protospacer
* ******.************** **. * .. 

757. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NC_031279 (Mycobacterium phage Bactobuster, complete genome) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcggtctggtcgacctcgccggtaaggc	Protospacer
* *********** ***** ******   . .*

758. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to KJ477077 (Pseudomonas phage JD024, complete genome) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcgatctgctcgacgtcggcgtccttgg	Protospacer
* ******.************** **. * .. 

759. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to JX434030 (Pseudomonas phage JBD5, complete genome) position: , mismatch: 9, identity: 0.727

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
cggcggcgatctgctcgacgtcggcgtccttgg	Protospacer
* ******.************** **. * .. 

760. spacer 33.4|4974253|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP010024 (Paraburkholderia fungorum strain ATCC BAA-463 plasmid pBIL, complete sequence) position: , mismatch: 9, identity: 0.727

atcgaggaccaggtgcaggctgccggccggggc	CRISPR spacer
acgatcgacctggtgcaggctgccgggcggacc	Protospacer
*. .  **** *************** ***. *

761. spacer 33.7|4974438|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.727

cgcagccggcccggcggaggccaggccgatgat	CRISPR spacer
ccccgccgacccggcggaggccaagccggcccg	Protospacer
* * ****.**************.****..   

762. spacer 33.7|4974438|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 9, identity: 0.727

cgcagccggcccggcggaggccaggccgatgat	CRISPR spacer
ccccgccgacccggcggaggccaagccggcccg	Protospacer
* * ****.**************.****..   

763. spacer 33.7|4974438|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 9, identity: 0.727

cgcagccggcccggcggaggccaggccgatgat	CRISPR spacer
ccccgccgacccggcggaggccaagccggcccg	Protospacer
* * ****.**************.****..   

764. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP019604 (Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence) position: , mismatch: 9, identity: 0.735

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
tcggccacgacagcgatccggtcgagctttctga	Protospacer
****************** **.***  *. ..*.

765. spacer 34.1|4978725|34|CP025990|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 9, identity: 0.735

tcggccacgacagcgatcaggccgacatcgtcgg	CRISPR spacer
agcgccacgacagccatcaggcggacagaggcga	Protospacer
   *********** ******* ****  * **.

766. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.719

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
tgcaggtcggcgaaggcggcctcgcgggcgtc	Protospacer
.* * *** **** **************   .

767. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 9, identity: 0.719

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
gctgtgtccgcgtcggcggcctcgaggcctat	Protospacer
   .******** *********** **  *.*

768. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.719

tggagcttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
acgtcattcgaagcaaccgccgccgcaatcaa	Protospacer
  *   *****.* ****************..

769. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tggagcttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
ggcagcttcaaggaagccgccgccgcgctgca	Protospacer
 * ******.*****.**********. *  .

770. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
tgatttgccggtgccggtgtggccggtgatga	Protospacer
   . ******** **************  * 

771. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP041605 (Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cggcgtgccggtggcggcctggccggtgctcg	Protospacer
   **************. *********.   

772. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP048642 (Streptomyces aureoverticillatus strain HN6 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gggggtgccggtggtggagtggccggtgctcg	Protospacer
*   **********.** **********.   

773. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP042825 (Rhizobium sp. WL3 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gcctgtgtcggtggcggtgtggcgctcgccgc	Protospacer
***.***.***************   .*. *.

774. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgtggtgccggtggcggtcaggccggtcaggc	Protospacer
  . **************  *******  **.

775. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
ctcgatgccggtggcggtgccgccggtggagc	Protospacer
 .* .**************. ******* .*.

776. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_LT703506 (Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 2) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
acggcgaccgggggaggtgtggccggtgtgat	Protospacer
.*    .**** ** ***************.*

777. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgtggtgccggtggcggtcaggccggtcaggc	Protospacer
  . **************  *******  **.

778. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP046510 (Erwinia sp. J780 plasmid pla1, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
gttattgccggtggcggtatggtcggtggtct	Protospacer
*..  *************.***.*****   *

779. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP039644 (Azospirillum sp. TSA2s plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgcatcgctggtggtggtgtggccggtgtagg	Protospacer
  *  .**.*****.**************.* 

780. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to MN617843 (Mycobacterium phage Quesadilla, complete genome) position: , mismatch: 9, identity: 0.719

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgcgaggccggtggcggtgaggctggtgtcga	Protospacer
  * . ************* ***.***** * 

781. spacer 36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045411 (Roseovarius sp. THAF8 plasmid pTHAF8_a, complete sequence) position: , mismatch: 9, identity: 0.735

----ccagtacctctactactcgtccctcggcctcgtc	CRISPR spacer
ttccctgg----tcaactattcgtccctcggcctcggc	Protospacer
    *..*    ** ****.**************** *

782. spacer 36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045394 (Roseovarius sp. THAF27 plasmid pTHAF27_a, complete sequence) position: , mismatch: 9, identity: 0.735

----ccagtacctctactactcgtccctcggcctcgtc	CRISPR spacer
ttccctgg----tcaactattcgtccctcggcctcggc	Protospacer
    *..*    ** ****.**************** *

783. spacer 36.4|5001328|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045405 (Roseovarius sp. THAF9 plasmid pTHAF9_a, complete sequence) position: , mismatch: 9, identity: 0.735

----ccagtacctctactactcgtccctcggcctcgtc	CRISPR spacer
ttccctgg----tcaactattcgtccctcggcctcggc	Protospacer
    *..*    ** ****.**************** *

784. spacer 36.5|5001390|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MK249149 (Blackfly microvirus SF02 isolate 045, complete genome) position: , mismatch: 9, identity: 0.727

tcgatgaggcggtgcttcgacaggagcgcagcc	CRISPR spacer
cttttgaggcggagtttcgacaggagcgggggc	Protospacer
..  ******** *.************* .* *

785. spacer 36.6|5001451|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.727

gacggcgtgaacccgcgccaccggtgcctcttg	CRISPR spacer
cgccgcgtgaacccgcgccactggcgccgccat	Protospacer
 .* *****************.**.*** *.  

786. spacer 38.9|5444530|36|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030863 (Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.75

ggggccggggcggcggcggtggcggtccggggcgtc	CRISPR spacer
atgagcggggcggcggcggtggcggcccgggtgagc	Protospacer
. *. ********************.*****  . *

787. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.719

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
tgcaggtcggcgaaggcggcctcgcgggcgtc	Protospacer
.* * *** **** **************   .

788. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 9, identity: 0.719

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
gctgtgtccgcgtcggcggcctcgaggcctat	Protospacer
   .******** *********** **  *.*

789. spacer 40.2|5592159|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021004 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pE, complete sequence) position: , mismatch: 9, identity: 0.727

gcccccgaagaacgaccccagcagcaagccccc	CRISPR spacer
tcagaagaagaacgaccctagcagcaagccgat	Protospacer
 *    ************.***********  .

790. spacer 40.2|5592159|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KC170285 (Uncultured bacterium plasmid pMBUI2, complete sequence) position: , mismatch: 9, identity: 0.727

gcccccgaagaacgaccccagcagcaagccccc	CRISPR spacer
tcagaaaaagaacgaccccagcagcaggcccat	Protospacer
 *    .*******************.**** .

791. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gtcgaaggcggcctccaggcggcggcgcatcgg	Protospacer
    . ****** ************* ***** 

792. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
aatgccggcggcgcgcaggcggcggcccaagcc	Protospacer
 *   ********. **************   *

793. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to AP017627 (Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
cagcgcggcggcgtcgcggcggcgggcggcgaa	Protospacer
***************  ******** * .. . 

794. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
aatgccggcggcgcgcaggcggcggcccaggcc	Protospacer
 *   ********. **************   *

795. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gatgccggcggcgcgcaggcggcggcccaggcc	Protospacer
 *   ********. **************   *

796. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
cagcgcggcggcgcccgggcggcgcaggccggc	Protospacer
*************.**.*******     . **

797. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
gatgccggcggcgcgcaggcggcggcccaggcc	Protospacer
 *   ********. **************   *

798. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.727

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ccatctggcggtcaccgtcggcgctgccggcga	Protospacer
 *   *  *****  ***************** 

799. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.727

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ccatctggcggtcaccgtcggcgctgccggcga	Protospacer
 *   *  *****  ***************** 

800. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.727

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ccatctggcggtcaccgtcggcgctgccggcga	Protospacer
 *   *  *****  ***************** 

801. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.727

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ccatctggcggtcaccgtcggcgctgccggcga	Protospacer
 *   *  *****  ***************** 

802. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.727

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
ccatctggcggtcgccgtcggcgctgccggcga	Protospacer
 *   *  *****  ***************** 

803. spacer 41.5|5593974|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012183 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence) position: , mismatch: 9, identity: 0.727

gccagtcccggtctgcgtcggcgctgccggcgc	CRISPR spacer
gcttcacccggtctgcgtagacgctgccggtat	Protospacer
**.   ************ *.*********...

804. spacer 41.6|5594035|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 9, identity: 0.727

gcccgcccggctgcgggccttctcc---ctcgagaa	CRISPR spacer
ccccgcccggctgcgcgccgtctccgcgtccgg---	Protospacer
 ************** *** *****   ..**.   

805. spacer 41.11|5594341|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 9, identity: 0.727

cgcgaaaacggattctgggaagacaccgacgtt	CRISPR spacer
aatgcaaacggaatctgggaggacaccgatggc	Protospacer
 ..* ******* *******.********.* .

806. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP024426 (Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence) position: , mismatch: 9, identity: 0.735

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
gctgctggacggccagggcgtgatccgcgccaag	Protospacer
  * * ***** **************** **.. 

807. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020445 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.735

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
gctgctggacggccagggcgtgatccgcgccaag	Protospacer
  * * ***** **************** **.. 

808. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
gctgctggacggccagggcgtgatccgcgccaag	Protospacer
  * * ***** **************** **.. 

809. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 9, identity: 0.735

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
gctgctggacggccagggcgtgatccgcgccaag	Protospacer
  * * ***** **************** **.. 

810. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 9, identity: 0.735

cgtccgggacgcccagggcgtgatccgctccggc-----	CRISPR spacer
ggtccgggtcgcccagggcgt-----gctcgagcagcca	Protospacer
 ******* ************     **** .**     

811. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 9, identity: 0.735

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
cgtccgggtcgcccagggagtgatgccgcgaagc	Protospacer
******** ********* ***** *  .  .**

812. spacer 41.15|5594462|32|CP025990|PILER-CR matches to CP003180 (Sulfobacillus acidophilus DSM 10332 plasmid, complete sequence) position: , mismatch: 9, identity: 0.719

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gttccgggacgccgagggcgttatcacgggcg	Protospacer
  *********** ******* ***     **

813. spacer 43.6|6196176|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP040453 (Halomonas sp. PA16-9 plasmid p_unnamed2, complete sequence) position: , mismatch: 9, identity: 0.727

ccggacgaacgccacgctccggcacctcgacca	CRISPR spacer
gctcagcgccgccatcctccggcacctcgacca	Protospacer
 *  *  . *****. *****************

814. spacer 47.27|6792007|36|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 9, identity: 0.75

tgggtcgccggcgccgcctgccgggacaccgacccc	CRISPR spacer
ctgcgcgcctgcgccgcctgccgggacgccgtcgac	Protospacer
. *  **** *****************.*** *  *

815. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP053710 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
gagctggcggtcctcaatctgacttacagtga	Protospacer
*  ************** *****.***. .. 

816. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MF766045 (Streptomyces phage Daudau, complete genome) position: , mismatch: 10, identity: 0.706

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
gtcctgccacagcgccatcgcctcctggacagtc	Protospacer
*.******** ****** *********  ...  

817. spacer 4.4|207618|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
accgccggggagagctggccgcccgcaggcgccg	Protospacer
 ********  **************.  . *.*.

818. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
gcgcccatcgaccgccaccagcacggcgtcggc	Protospacer
..  ******************* *.**  . *

819. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP022318 (Brachybacterium avium strain VR2415 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.697

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
ctcgccatcgacctcgaccagcagggcaacctg	Protospacer
 ************ * *********.*..  . 

820. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
gcgcccatcgaccgccaccagcacggcgtcggc	Protospacer
..  ******************* *.**  . *

821. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
gcgcccatcgaccgccaccagcacggcgtcggc	Protospacer
..  ******************* *.**  . *

822. spacer 4.5|207680|33|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

atcgccatcgaccgccaccagcaggacgggacc	CRISPR spacer
gcgcccatcgaccgccaccagcacggcgtcggc	Protospacer
..  ******************* *.**  . *

823. spacer 4.6|207741|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tccgccgggccgagctggccgcccgtccaagtca	CRISPR spacer
accgccggggagagctggccgcccgcaggcgccg	Protospacer
 ********  **************.  . *.*.

824. spacer 6.1|408245|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_010553 (Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence) position: , mismatch: 10, identity: 0.714

tgctcccat-----cggaggaccggcggagcgtcgtcgtg	CRISPR spacer
-----ctgtggacgaggatgaccggcgcagcgtcgtcgtg	Protospacer
     *..*      *** ******** ************

825. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

826. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

827. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgctcggcgcgcaccgcgacgacctcccggccatc	Protospacer
.*****************.*** ***   **    

828. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

829. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_016591 (Burkholderia sp. YI23 plasmid byi_2p, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
taccaggcgcgcagcgcggcgagctcgtcggcacg	Protospacer
..*. ******** ************* **    *

830. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP000617 (Burkholderia vietnamiensis G4 plasmid pBVIE01, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
taccaggcgcgcagcgcggcgagctcgtcggcacg	Protospacer
..*. ******** ************* **    *

831. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

832. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

833. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

834. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

835. spacer 6.6|408571|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

cgctcggcgcgcaccgcggcgagctcggcgcgcag	CRISPR spacer
tgggcacgccgcaccgcggccagcgcggcgcgcat	Protospacer
.*  *.   *********** *** ********* 

836. spacer 8.1|478685|32|CP025990|CRISPRCasFinder matches to NZ_CP025513 (Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gacaacggccgcgcggccagctcgacaaaccc	CRISPR spacer
cacaactgccgcgcggccagatcggctgcagg	Protospacer
 ***** ************* ***.* .    

837. spacer 8.5|478929|32|CP025990|CRISPRCasFinder matches to NZ_CP045120 (Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gcgccccggacgcggacgtcctcgaactcctg	CRISPR spacer
cggccacggacgccgacgtcctcgacgccgcc	Protospacer
  *** ******* ***********  .* . 

838. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 10, identity: 0.688

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggccgtgctggtcgtcggcggggtcgctt	Protospacer
 ********* ******.****** *   .  

839. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.688

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcgaccgtgaaggtcgccggcggcttgcctt	Protospacer
 ***.****** ************.  .*.  

840. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_012520 (Rhodococcus opacus B4 plasmid pROB01, complete sequence) position: , mismatch: 10, identity: 0.688

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggcggtgatggtcgccagcgggctgcgca	Protospacer
 ***** ************.****   .*  .

841. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to CP054917 (Streptomyces sp. NA02950 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
tgcggcagtgatggtcgccgccgcctccttct	Protospacer
****** ************* ** .   .*  

842. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 10, identity: 0.688

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
agcggccgagatggttgccggcggccttgccg	Protospacer
 ******* ******.********.    . *

843. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NZ_CP006990 (Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence) position: , mismatch: 10, identity: 0.697

gcgatctcaccgatcccgcgccgctggtggatc	CRISPR spacer
tcgctctcaccgattccgcgccgctcatcatcg	Protospacer
 ** **********.********** .* . . 

844. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 10, identity: 0.697

gcgatctcaccgatcccgcgccgctggtggatc	CRISPR spacer
tcgctctcaccgattccgcgccgctcatcatcg	Protospacer
 ** **********.********** .* . . 

845. spacer 8.9|478807|33|CP025990|PILER-CR,CRT matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 10, identity: 0.697

gcgatctcaccgatcccgcgccgctggtggatc	CRISPR spacer
tcgctctcaccgattccgcgccgctcatcatcg	Protospacer
 ** **********.********** .* . . 

846. spacer 9.9|481683|35|CP025990|CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 10, identity: 0.714

cgggcacaccacgccctcgtccggcgcgtcgactt	CRISPR spacer
atgcagcaccacgcgctcgtgcggcgcgtcggcgg	Protospacer
  *  .******** ***** **********.*  

847. spacer 9.9|481683|35|CP025990|CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.714

cgggcacaccacgccctcgtccggcgcgtcgactt	CRISPR spacer
atgcagcaccacgcgctcgtgcggcgcgtcggcgg	Protospacer
  *  .******** ***** **********.*  

848. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_023282 (Streptomyces sp. FR1 plasmid pFRL2, complete sequence) position: , mismatch: 10, identity: 0.706

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
gaaaccctggcccggcaggccgccgaccacggcg	Protospacer
   .************  ***********    *

849. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to JN106175 (Uncultured bacterium plasmid pAKD34, complete sequence) position: , mismatch: 10, identity: 0.706

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
cagcgcatggcccagcatgccgccgaccagcgcg	Protospacer
.    * ******.** **************  *

850. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 10, identity: 0.706

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
cggcctcccgcccggccggccgcggaccagccac	Protospacer
.   *.*. ******** ***** ********* 

851. spacer 11.1|711686|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to CP053333 (Salmonella enterica subsp. diarizonae serovar 47:k:z35 strain 2009K1094 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ggggtcggcatccggccggctgaccgtcacgtcg	CRISPR spacer
cccgtctgaatccggccggctgaccgtcgtccgg	Protospacer
   *** * *******************.. . *

852. spacer 11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH454080 (Paenibacillus phage Ley, complete genome) position: , mismatch: 10, identity: 0.697

ccatgctcgcctcgggcggcactggcccgacgg	CRISPR spacer
gttggctcgactcgggcggcactgacccggaat	Protospacer
 .  ***** **************.****. . 

853. spacer 11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH454076 (Paenibacillus phage Ash, complete genome) position: , mismatch: 10, identity: 0.697

ccatgctcgcctcgggcggcactggcccgacgg	CRISPR spacer
gttggctcgactcgggcggcactgacccggaat	Protospacer
 .  ***** **************.****. . 

854. spacer 11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH431938 (Paenibacillus phage C7Cdelta, complete genome) position: , mismatch: 10, identity: 0.697

ccatgctcgcctcgggcggcactggcccgacgg	CRISPR spacer
gttggctcgactcgggcggcactgacccggaat	Protospacer
 .  ***** **************.****. . 

855. spacer 11.3|711809|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KT755656 (Paenibacillus phage Tripp, complete genome) position: , mismatch: 10, identity: 0.697

ccatgctcgcctcgggcggcactggcccgacgg	CRISPR spacer
gttggctcgactcgggcggcactgacccggaat	Protospacer
 .  ***** **************.****. . 

856. spacer 14.1|1142149|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

tcctccagcagcgcgacgacgtcgacgaccttcgc	CRISPR spacer
tcccgcagcagcgcgacgacgtcgaacgcaggcaa	Protospacer
***. ********************  .*   *. 

857. spacer 14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KY365739 (Streptomyces phage BabyGotBac, complete genome) position: , mismatch: 10, identity: 0.714

accgggacaccggggacgcctgcgacgccgacggg	CRISPR spacer
gtggctgcaccggggacacctgcgacggcgactgc	Protospacer
.. *  .**********.********* **** * 

858. spacer 14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH178382 (Streptomyces phage Salete, complete genome) position: , mismatch: 10, identity: 0.714

accgggacaccggggacgcctgcgacgccgacggg	CRISPR spacer
gtggctgcaccggggacacctgcgacggcgactgc	Protospacer
.. *  .**********.********* **** * 

859. spacer 14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KU189325 (Streptomyces phage Maih, complete genome) position: , mismatch: 10, identity: 0.714

accgggacaccggggacgcctgcgacgccgacggg	CRISPR spacer
gtggctgcaccggggacacctgcgacggcgactgc	Protospacer
.. *  .**********.********* **** * 

860. spacer 14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MH178381 (Streptomyces phage BayC, complete genome) position: , mismatch: 10, identity: 0.714

accgggacaccggggacgcctgcgacgccgacggg	CRISPR spacer
gtggctgcaccggggacacctgcgacggcgactgc	Protospacer
.. *  .**********.********* **** * 

861. spacer 14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_047756 (Caulobacter phage Sansa, complete genome) position: , mismatch: 10, identity: 0.714

accgggacaccggggacgcctgcgacgccgacggg	CRISPR spacer
gccgggacatcggcgacgcctgcgacaagatcctg	Protospacer
.********.*** ************.  . *  *

862. spacer 14.6|1142478|35|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to KP876466 (Streptomyces phage TP1604, complete genome) position: , mismatch: 10, identity: 0.714

accgggacaccggggacgcctgcgacgccgacggg	CRISPR spacer
gtggctgcaccggggacacctgcgacggcgactgc	Protospacer
.. *  .**********.********* **** * 

863. spacer 14.10|1142741|36|CP025990|CRISPRCasFinder,CRT matches to NZ_CP045120 (Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.722

gtgccggccaggcgcagcagcgccggcaggtcccat	CRISPR spacer
tcgccggccaggcggagcagggccggcacgagcacg	Protospacer
 .************ ***** ******* *  *   

864. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_010811 (Ralstonia phage RSL1, complete genome) position: , mismatch: 10, identity: 0.688

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
acttggatggcggagatcgcatggtccacgtg	Protospacer
  .  *************** ***.****   

865. spacer 18.3|2981990|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to AB366653 (Ralstonia phage RSL1 DNA, complete genome) position: , mismatch: 10, identity: 0.688

tgcgtgatggcggagatcgcctggcccactat	CRISPR spacer
acttggatggcggagatcgcatggtccacgtg	Protospacer
  .  *************** ***.****   

866. spacer 24.1|3572195|32|CP025990|PILER-CR matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gggtgcggccggtcggacctgacggcgctccg	CRISPR spacer
cgacgcggccggtcggctctgacggcggggtc	Protospacer
 *..************ .*********   . 

867. spacer 26.1|3610301|33|CP025990|CRT matches to NZ_CP049358 (Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cgacgtggcgggttgacggacggccgccacctg	CRISPR spacer
gcgcatggcgggctgacggacggcctccagagt	Protospacer
  .*.*******.************ ***    

868. spacer 26.1|3610301|33|CP025990|CRT matches to NZ_CP031159 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence) position: , mismatch: 10, identity: 0.697

cgacgtggcgggttgacggacggccgccacctg	CRISPR spacer
gcgcatggcgggctgacggacggcctccagagt	Protospacer
  .*.*******.************ ***    

869. spacer 26.1|3610301|33|CP025990|CRT matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 10, identity: 0.697

cgacgtggcgggttgacggacggccgccacctg	CRISPR spacer
aaccgtgacgggttgacggtcggccgcatcaca	Protospacer
 . ****.*********** *******  * ..

870. spacer 26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder matches to NC_009470 (Acidiphilium cryptum JF-5 plasmid pACRY04, complete sequence) position: , mismatch: 10, identity: 0.706

cctggcggccttcacggcgtcggcgtagcagtgc	CRISPR spacer
tctggcggccttcaaggcggcggcgccctatctc	Protospacer
.************* **** *****.  .* . *

871. spacer 26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder matches to NC_015188 (Acidiphilium multivorum AIU301 plasmid pACMV4, complete sequence) position: , mismatch: 10, identity: 0.706

cctggcggccttcacggcgtcggcgtagcagtgc	CRISPR spacer
tctggcggccttcaaggcggcggcgccctatctc	Protospacer
.************* **** *****.  .* . *

872. spacer 26.11|3610485|33|CP025990|PILER-CR,CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cgcacgggccgtgcggcgggtggcgtggtggag	CRISPR spacer
gggccgggccgtgcggcgtgcggcgtgggccgt	Protospacer
 *  ************** *.*******   . 

873. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
agcggctggccgttgccgacgaagacgttata	Protospacer
.  . ****************** .****   

874. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 10, identity: 0.688

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
agcggctggccgttgccgacgaagacgttata	Protospacer
.  . ****************** .****   

875. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
agcttctgcccgttgacgacgaacgcgtcgcc	Protospacer
.   .*** ****** ************.  *

876. spacer 29.5|4677597|33|CP025990|CRISPRCasFinder,CRT matches to MN694715 (Marine virus AFVG_250M935, complete genome) position: , mismatch: 10, identity: 0.697

ggcctcctgcttcaagttcgtgaagtcgttggc	CRISPR spacer
ctttctctgcttctagttcctgaagtcgttgaa	Protospacer
  ....******* ***** ***********. 

877. spacer 30.1|4939798|34|CP025990|CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcgatccctccccggtcggccgccgccgggcgc	CRISPR spacer
gacctcgtcgccccggtcgaccgccgcctggcgc	Protospacer
 .*  . .* *********.******** *****

878. spacer 30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020040 (Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence) position: , mismatch: 10, identity: 0.714

gtggcgctggaccgggtcgaggcggctcggcccct	CRISPR spacer
cgggcgctggagcgggtggaggcggctggaggcac	Protospacer
  ********* ***** ********* *.  * .

879. spacer 31.2|4968703|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_014563 (Pantoea vagans C9-1 plasmid pPag2, complete sequence) position: , mismatch: 10, identity: 0.688

gacctgggccatgtcgtgtccaaccggaccgt	CRISPR spacer
gcaactggccatgtggtgtacaaccggacttc	Protospacer
*   . ******** **** *********. .

880. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ggccgccgacacggccagcgtcgcgcccacca	Protospacer
 .  .* ..********* .************

881. spacer 31.4|4968825|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP027239 (Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

caggacgagcacggccaggatcgcgcccacca	CRISPR spacer
ggtggtcgccacggcccggatcgcggccacca	Protospacer
 . *.. . ******* ******** ******

882. spacer 32.4|4969314|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MF459647 (Erwinia phage vB_EamM_Joad, complete genome) position: , mismatch: 10, identity: 0.688

gtccaccgccgccaatccagtcggccccgggg	CRISPR spacer
ccccaccgcctccgatccagtcggcttcaact	Protospacer
 .******** **.***********..*..  

883. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035092 (Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

atcgtgcagcgtcgcccggccggcaacacggc	CRISPR spacer
gtgatgcagcggcgcgcggccggcaaccttca	Protospacer
.* .******* *** *********** .   

884. spacer 32.5|4969375|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_008688 (Paracoccus denitrificans PD1222 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.688

atcgtgcagcgtcgcccggccggcaacacggc	CRISPR spacer
gtgatgcagcggcgcgcggccggcaaccttca	Protospacer
.* .******* *** *********** .   

885. spacer 32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 10, identity: 0.688

tccttgaacccgattgggtcagacgaaacccg	CRISPR spacer
cctccacgcccgattgggaccgacgaaacccc	Protospacer
.*.... .********** * ********** 

886. spacer 32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 10, identity: 0.688

tccttgaacccgattgggtcagacgaaacccg	CRISPR spacer
cctccacgcccgattgggaccgacgaaacccc	Protospacer
.*.... .********** * ********** 

887. spacer 32.6|4969436|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 10, identity: 0.688

tccttgaacccgattgggtcagacgaaacccg	CRISPR spacer
cctccacgcccgattgggaccgacgaaacccc	Protospacer
.*.... .********** * ********** 

888. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 10, identity: 0.697

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
tgtcggcggtctgctgcacgtcgccgccgacct	Protospacer
.  ************  **********  .* .

889. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to MH426726 (Erwinia phage Pavtok, complete genome) position: , mismatch: 10, identity: 0.697

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
gaagggcgatccgctcgacgtcgccgcgtatgc	Protospacer
  . ****.**.****************....*

890. spacer 33.3|4974192|33|CP025990|CRISPRCasFinder,CRT matches to NC_028849 (Mycobacterium phage Luchador, complete genome) position: , mismatch: 10, identity: 0.697

ccgcggcggtctgctcgacgtcgccgcgcgcac	CRISPR spacer
tggcggcggtctggtcgacatcgccggtaaggc	Protospacer
. *********** *****.******   . .*

891. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
cggatggccgcgacgtcggcctcgatcagccg	Protospacer
****** ******** ********   ...  

892. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_LR134469 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
gggatgcccacgacggcggcctcggcgatctc	Protospacer
 *****.**.**************  *. . .

893. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aggaagtccgcgacgccggcctcgtcgaggtc	Protospacer
 *** ********** ********. *..  .

894. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP036516 (Lichenihabitans psoromatis strain PAMC 29148 plasmid p_unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aggatgtccgcgatgtcggcctcggtctttcc	Protospacer
 ************.* ********     * .

895. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031599 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence) position: , mismatch: 10, identity: 0.688

tggagcttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
ctggcgaccgaggaaaccgccgccgctgtcgc	Protospacer
. *.   .****************** .*** 

896. spacer 35.3|4979143|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to MH229864 (Streptomyces phage UNTPL, complete genome) position: , mismatch: 10, identity: 0.688

tggagcttcgaggaaaccgccgccgcaatcgg	CRISPR spacer
cagagcttccaggaagccgccgccggtacatc	Protospacer
..******* *****.*********  *.   

897. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 10, identity: 0.688

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
agcgacagcggtggcggtggggccggtgaggc	Protospacer
. * ... *********** ******** **.

898. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP016618 (Microvirga ossetica strain V5/3m plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
aatcgtgccggtggcggcgtcgccggcggcaa	Protospacer
. .**************.** *****.*  . 

899. spacer 37.1|5319744|34|CP025990|PILER-CR matches to NC_008441 (Streptomyces laurentii plasmid pSLS DNA, complete sequence) position: , mismatch: 10, identity: 0.706

acccggctacggcgacccgtcccagcagggggcc	CRISPR spacer
acccgcccacggcgacccgtcccacgcgaaattc	Protospacer
***** *.****************   *... .*

900. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
cggatggccgcgacgtcggcctcgatcagccg	Protospacer
****** ******** ********   ...  

901. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134469 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
gggatgcccacgacggcggcctcggcgatctc	Protospacer
 *****.**.**************  *. . .

902. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aggaagtccgcgacgccggcctcgtcgaggtc	Protospacer
 *** ********** ********. *..  .

903. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036516 (Lichenihabitans psoromatis strain PAMC 29148 plasmid p_unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
aggatgtccgcgatgtcggcctcggtctttcc	Protospacer
 ************.* ********     * .

904. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN871452 (UNVERIFIED: Serratia phage KpZh_1, complete genome) position: , mismatch: 10, identity: 0.697

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tagcgcggcggcgttccggcggcggtaaccctt	Protospacer
.*************.* ********.   .* .

905. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN871447 (UNVERIFIED: Serratia phage KpLz_1_41, complete genome) position: , mismatch: 10, identity: 0.697

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tagcgcggcggcgttccggcggcggtaaccctt	Protospacer
.*************.* ********.   .* .

906. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN871453 (UNVERIFIED: Serratia phage KpZh_LPS_45, complete genome) position: , mismatch: 10, identity: 0.697

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tagcgcggcggcgttccggcggcggtaaccctt	Protospacer
.*************.* ********.   .* .

907. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN871451 (UNVERIFIED: Serratia phage KpYy_2_45, complete genome) position: , mismatch: 10, identity: 0.697

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tagcgcggcggcgttccggcggcggtaaccctt	Protospacer
.*************.* ********.   .* .

908. spacer 41.3|5593852|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to MN871448 (UNVERIFIED: Serratia phage KpSz_1, complete genome) position: , mismatch: 10, identity: 0.697

cagcgcggcggcgtccaggcggcggcccatcgc	CRISPR spacer
tagcgcggcggcgttccggcggcggtaaccctt	Protospacer
.*************.* ********.   .* .

909. spacer 41.13|5594462|34|CP025990|CRISPRCasFinder,CRT matches to NZ_CP029174 (Methylobacterium sp. DM1 plasmid pLVM1, complete sequence) position: , mismatch: 10, identity: 0.706

cgtccgggacgcccagggcgtgatccgctccggc	CRISPR spacer
gttgctcgacgccgagggcgtgatccgcgccaag	Protospacer
  * *  ****** ************** **.. 

910. spacer 41.15|5594462|32|CP025990|PILER-CR matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 10, identity: 0.688

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
ggtccgggtcgcccagggcgtgctcgagcagc	Protospacer
 ******* ************* ** . .   

911. spacer 41.15|5594462|32|CP025990|PILER-CR matches to KX576640 (Arthrobacter phage RcigaStruga, complete genome) position: , mismatch: 10, identity: 0.688

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gcacaaggacgccgagggcgagatccgcttga	Protospacer
   * .******* ****** ********. .

912. spacer 41.15|5594462|32|CP025990|PILER-CR matches to MG210949 (Arthrobacter phage Huntingdon, complete genome) position: , mismatch: 10, identity: 0.688

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
gcacaaggacgccgagggcgagatccgcttga	Protospacer
   * .******* ****** ********. .

913. spacer 41.15|5594462|32|CP025990|PILER-CR matches to EF579802 (Microbacterium phage Min1, complete genome) position: , mismatch: 10, identity: 0.688

cgtccgggacgcccagggcgtgatccgctccg	CRISPR spacer
cgtgcgggacgcccagggcatgacaggacgga	Protospacer
*** ***************.***.  * .  .

914. spacer 42.2|5600635|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 10, identity: 0.697

ctcgacctcggctgcggggagatcggcctcccg	CRISPR spacer
ctcgacctcggctacggggagaccgatgcggac	Protospacer
*************.********.**.. .    

915. spacer 43.3|6195993|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 10, identity: 0.697

cgcgtcgccgagacccgccgatctggcgatctt	CRISPR spacer
tagatcgccgagacccgccgttttggcgggcgc	Protospacer
.. .**************** *.*****. * .

916. spacer 43.5|6196115|33|CP025990|CRISPRCasFinder,CRT matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 10, identity: 0.697

gctgcgcccgcgccgcacgccggtccgccggag	CRISPR spacer
cgagaccccgcgccgcaccgcggtccgccgcgt	Protospacer
   *  ************  ********** . 

917. spacer 43.9|6196359|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 10, identity: 0.697

ccctggccccggtccgccgccgcctgatcgccc	CRISPR spacer
ggtgagcgccggtccgccggcgcctgatcttcg	Protospacer
  . .** *********** ********* .* 

918. spacer 44.4|6577474|33|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 10, identity: 0.697

tccgtactgagcgccttgacggcgcggatctca	CRISPR spacer
tagtggctgagcgcgttgaccgcgcggatcgac	Protospacer
*    .******** ***** *********   

919. spacer 47.23|6791718|35|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 10, identity: 0.714

gggtccagcgtcgccatcgcgagacgcggcgtcgg	CRISPR spacer
ttttccagcgtcgcgatcgccagacgcgcccgcac	Protospacer
   *********** ***** ******* *  *. 

920. spacer 47.27|6792007|36|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 10, identity: 0.722

tgggtcgccggcgccgcctgccgggacaccgacccc	CRISPR spacer
ctgcgcgcctgcgccgcctgccgggacgccgtcgat	Protospacer
. *  **** *****************.*** *  .

921. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP012659 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence) position: , mismatch: 10, identity: 0.688

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
tcggtgggggtcctcaagctgacatacattta	Protospacer
 *  *** *************** ***...  

922. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP012659 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence) position: , mismatch: 10, identity: 0.688

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
tcggtgggggtcctcaagctgacatacattta	Protospacer
 *  *** *************** ***...  

923. spacer 48.1|6810224|32|CP025990|CRISPRCasFinder matches to NZ_CP029972 (Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence) position: , mismatch: 10, identity: 0.688

gccctggcggtcctcaagctgacctacgccac	CRISPR spacer
tcggtgggggtcctcaagctgacatacattta	Protospacer
 *  *** *************** ***...  

924. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

925. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

926. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

927. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

928. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

929. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

930. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

931. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

932. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

933. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

934. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

935. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

936. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

937. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

938. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

939. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
ggattgccactgagccaacgccccctgccgcccc	Protospacer
*  .******** *********.*****.     

940. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

941. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

942. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

943. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

944. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

945. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

946. spacer 3.3|135512|34|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

gccctgccactgcgccaacgcctcctgcttgagg	CRISPR spacer
cttgtgccagtgcgccagcgcctcctgcgcaccg	Protospacer
 .. ***** *******.********** ..  *

947. spacer 6.8|408703|37|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 11, identity: 0.703

atgatgctgcccaccgggtccacggtgggctcgacct	CRISPR spacer
cccgggttgcccaccgggtcgacggggggctcggcga	Protospacer
 . . *.************* **** *******.*  

948. spacer 8.4|478868|32|CP025990|CRISPRCasFinder matches to MG872834 (Gordonia phage Confidence, complete genome) position: , mismatch: 11, identity: 0.656

aggacttcaccgccggagagagcacggtcgtc	CRISPR spacer
gatcacgcaccgccggagagatcacgttcgat	Protospacer
..   . ************** **** *** .

949. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.656

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
ggcggatgtgatggtcgccggcggcatggaaa	Protospacer
 **** .*****************.. .  ..

950. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_010627 (Paraburkholderia phymatum STM815 plasmid pBPHY02, complete sequence) position: , mismatch: 11, identity: 0.656

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
agcggccgtgacggtcgcgggcggcacggcat	Protospacer
 **********.****** *****.. . .. 

951. spacer 8.6|478990|32|CP025990|CRISPRCasFinder matches to NC_018696 (Paraburkholderia phenoliruptrix BR3459a plasmid pSYMBR3459, complete sequence) position: , mismatch: 11, identity: 0.656

tgcggccgtgatggtcgccggcggtggactgg	CRISPR spacer
agcggccgtgacggtcgcgggcggcacggcat	Protospacer
 **********.****** *****.. . .. 

952. spacer 9.16|482147|32|CP025990|CRT matches to NC_007950 (Polaromonas sp. JS666 plasmid 2, complete sequence) position: , mismatch: 11, identity: 0.656

cgtggtcggacgtggtgtcgatcggcatgctt	CRISPR spacer
tcaagtcggacctggtgtcgaacggcaacgcc	Protospacer
.  .******* ********* *****   ..

953. spacer 10.7|555168|34|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_015724 (Cupriavidus necator N-1 plasmid pBB2, complete sequence) position: , mismatch: 11, identity: 0.676

tttgccctggcccggcctgccgccgaccagccag	CRISPR spacer
gcggaactggtccgggctgccgccgaccagttcc	Protospacer
 . *  ****.**** **************..  

954. spacer 13.21|792395|37|CP025990|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 11, identity: 0.703

gatgacggtctcccagctcatcgccgccctgtcccgg	CRISPR spacer
gccggcggtgtcccagcgcatcgccgccctggaggac	Protospacer
* .*.**** ******* *************    . 

955. spacer 18.7|2982234|32|CP025990|CRISPRCasFinder,CRT matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 11, identity: 0.656

ccgccacctgccggccgcatccgcaccccccg	CRISPR spacer
tcgccacgtcccggccgcatccgcgagattgt	Protospacer
.****** * **************.   ..  

956. spacer 19.3|3490795|37|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.703

ccgggctggcggaagtcgcggcgcagcgcgaaccaga	CRISPR spacer
atgtgctcgcggaactcgcggcgcagcgcgtgacgcg	Protospacer
 .* *** ****** *************** . *. .

957. spacer 26.2|3610358|37|CP025990|CRT matches to NZ_LR134450 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence) position: , mismatch: 11, identity: 0.703

ggacttcgacgggcagcggctgtttctcacccagtcg	CRISPR spacer
caccttcgacgggccgcggatgtttctcaacgcgcac	Protospacer
 . *********** **** ********* *  *.  

958. spacer 26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder matches to NZ_CP039426 (Citricoccus sp. SGAir0253 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.676

cctggcggccttcacggcgtcggcgtagcagtgc	CRISPR spacer
gatggacgccttcacggcgtcggcgtgcgggccg	Protospacer
  ***  *******************.  .*.  

959. spacer 26.10|3610423|34|CP025990|PILER-CR,CRISPRCasFinder matches to NZ_CP039431 (Citricoccus sp. SGAir0453 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.676

cctggcggccttcacggcgtcggcgtagcagtgc	CRISPR spacer
gatggacgccttcacggcgtcggcgtgcgggccg	Protospacer
  ***  *******************.  .*.  

960. spacer 28.2|4214497|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

gtgacctggccgttgccgacgaacgcgttcac	CRISPR spacer
agcggttggccattgccgacgaacacgttgta	Protospacer
.  . .*****.************.****   

961. spacer 30.3|4939927|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 11, identity: 0.686

gtggcgctggaccgggtcgaggcggctcggcccct	CRISPR spacer
cgggcgctggagcgggtggaggcggctggaggtgc	Protospacer
  ********* ***** ********* *.  . .

962. spacer 35.1|4979021|32|CP025990|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 11, identity: 0.656

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
gcgatgaccgcgacggcgacctcgccctccac	Protospacer
  **** ***********.******    ...

963. spacer 35.2|4979082|32|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 11, identity: 0.656

ccgttcccggccggtgatcagcatgacggtca	CRISPR spacer
tttggcccggtcggtgatctgcatgacgtgat	Protospacer
..   *****.******** ********    

964. spacer 35.4|4979204|32|CP025990|CRISPRCasFinder,CRT matches to NZ_CP032696 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525b, complete sequence) position: , mismatch: 11, identity: 0.656

gcccgtgccggtggcggtgtggccggtgtggt	CRISPR spacer
cgatttgccggtgccggtatggccggtgataa	Protospacer
   . ******** ****.*********  . 

965. spacer 39.2|5574151|32|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 11, identity: 0.656

cggatgtccgcgacggcggcctcgcgggatgt	CRISPR spacer
gcgatgaccgcgacggcgacctcgccctccac	Protospacer
  **** ***********.******    ...

966. spacer 41.4|5593913|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 11, identity: 0.667

ggtggatcagcccgccgacaacaaccccgccga	CRISPR spacer
acccccccagccccccgacaacacccccgcccc	Protospacer
. .   .****** ********* *******  

967. spacer 41.4|5593913|33|CP025990|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 11, identity: 0.667

ggtggatcagcccgccgacaacaaccccgccga	CRISPR spacer
acccccccagccccccgacaacacccccgcccc	Protospacer
. .   .****** ********* *******  

968. spacer 47.3|6790244|38|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NC_030907 (Gordonia phage GMA5, complete genome) position: , mismatch: 11, identity: 0.711

tcgcggctggcgtcgtgcgccgcccggtagcgggcggc	CRISPR spacer
cgacggcgggcgtcgtgcgacgcccggtagtcgtggtg	Protospacer
. .**** *********** **********. *  *  

969. spacer 47.24|6791790|35|CP025990|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013744 (Streptomyces sp. CdTB01 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

ccccgcctgatcggagacggccagggcgacgggat	CRISPR spacer
ggcgcgatgctcggcgacggccagggcgacggcca	Protospacer
  *    ** **** *****************   

970. spacer 30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 12, identity: 0.657

gtgccggcgtacgcccgccggcaccggcgggtcaa	CRISPR spacer
cctggagcgtccgcccgccggcaccggctggattc	Protospacer
 .   .**** ***************** ** .  

971. spacer 30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 12, identity: 0.657

gtgccggcgtacgcccgccggcaccggcgggtcaa	CRISPR spacer
cctggagcgtccgcccgccggcaccggctggattc	Protospacer
 .   .**** ***************** ** .  

972. spacer 30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 12, identity: 0.657

gtgccggcgtacgcccgccggcaccggcgggtcaa	CRISPR spacer
cctggagcgtccgcccgccggcaccggctggattc	Protospacer
 .   .**** ***************** ** .  

973. spacer 30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 12, identity: 0.657

gtgccggcgtacgcccgccggcaccggcgggtcaa	CRISPR spacer
cctggagcgtccgcccgccggcaccggctggattc	Protospacer
 .   .**** ***************** ** .  

974. spacer 30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 12, identity: 0.657

gtgccggcgtacgcccgccggcaccggcgggtcaa	CRISPR spacer
cctggagcgtccgcccgccggcaccggctggattc	Protospacer
 .   .**** ***************** ** .  

975. spacer 30.2|4939862|35|CP025990|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 12, identity: 0.657

gtgccggcgtacgcccgccggcaccggcgggtcaa	CRISPR spacer
cctggagcgtccgcccgccggcaccggctggattc	Protospacer
 .   .**** ***************** ** .  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2252700 : 2325731	59	Mycobacterium_phage(12.5%)	tRNA,holin,protease	NA
DBSCAN-SWA_2	4572796 : 4616063	46	Gordonia_phage(25.0%)	tRNA,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>CP025990|2252700:2325731|DBSCAN-SWA
ATCAGTCGTTCTCGGTGTCGTTCTGGTTCTCGGTGCTGGACCCACCCGAGCCGGACAGCTCCACCGGCGGCGAGTCCGGGACCTCGACCGGCTTGGTCTCGCCGCGGAAGACGAAGCGGGCCTCGTCGTCGCGCTTGTCCTCGCCGTCCCAGCCCTCGACGTCGGCGATGATGATCTGACCCGGCTGCAGCTCGCCGAACAGGATCTTCTCCGACAGCTGGTCCTCGATCTCCCGCTGGATCGTCCGCCGCAGCGGCCTGGCACCCAACACCGGGTCGAAGCCCCGCTTGGCCAGGAGCTTCTTGGCCTTCTCGGTCAGCTCCAGCGCCATGTCCTTGTTCTTGAGCTGCGTCTCGACGCGGGTCACCATCAGGTCCACCATCCGAACGATCTCGGACTCGGTCAGCTGGTGGAAGACGATGATGTCGTCGATCCGGTTCAGGAACTCCGGGCGGAAGTGCTTCTTCAGCTCGTCGTTGACCTTCTGCTTCATCCGCTCGTAGTTCGAGCCCTGCTCCCCGCTGCCGGAGAACCCGAGGCCCACCGCCTTGGAGATGTCCTGCGTGCCCAGGTTGGAGGTGAAGATGATGACGGTGTTCTTGAAGTCCACCGTCCGGCCCTGACCGTCGGTCAGGCGGCCGTCCTCCAGCACCTGGAGCAGCGTGTTGTACACCTCCTGGTGCGCCTTCTCGATCTCGTCGAACAGCACGACGGAGAACGGCTTGCGGCGCACCTTCTCGGTGAGCTGCCCGCCCTCCTCGTAGCCGACGTAGCCGGGAGGAGCACCGAACAGCCGCGAGGCGGTGTAGCGGTCGTGGAACTCGCCCATGTCGATCTGGACGAGCGCGTCGTCCTCACCGAACAGGAAGTTCGCCAGCGCCTTGGACAGCTCGGTCTTCCCCACACCGGACGGCCCGGCGAAGATGAACGAGCCGGAGGGGCGCTTGGGGTCCTTCAGCCCGGCCCGCGTGCGGCGGATCGCCTGGGAGACCGCCTTCACGGCGTCCTCCTGGCCGATGATCCGCTTGTGCAGCTCGTCCTCCATCCGGAGCAGGCGGGTGGTCTCCTCCTCCGTCAGTTTGAAGACCGGGATGCCGGTCCAGTTGCCGAGGACCTCGGCGATCTGCTCGTCGTCGACCTCCGCCACGACGTCCAGGTCACCGGACTTCCACTGCTTCTCGCGCTCGCCCTTCTGCGCGAGAAGCTGCTTCTCCTCGTCGCGCAGCCTGGCGGCCCGCTCGAAGTCCTGCGCGTCGATCGCGGACTCCTTGTCCCTGCGGACGTCGGCGATCTTCTCGTCGAACTCGCGCAGGTCCGGCGGCGCCGTCATCCGGCGGATCCGCATCCGGGCGCCCGCCTCGTCGATCAGGTCGATCGCCTTGTCCGGCAGGTAGCGGTCGTTGATGTACCTGTCGGCCAGGGTGGCCGCCGCGACCAGCGCGGAGTCGGTGATGGACACGCGGTGGTGGGCCTCGTAGCGGTCCCGCAGGCCCTTGAGGATCTCGATGGTGTGGTCCAGCGAGGGCTCGCCCACCTGGATGGGCTGGAAGCGGCGCTCCAGCGCCGGGTCCTTCTCGACGTGCTTGCGGTACTCGTCGAGGGTGGTGGCGCCGATCGTCTGCAACTCACCCCTGGCCAGCATGGGCTTGAGGATGCTGGCGGCGTCGATCGCGCCCTCGGCGGCGCCCGCTCCGACGAGCGTGTGCAGCTCGTCGATGAACAGGATGATGTCGCCCCGGGTGCGGATCTCCTTGAGCACCTTCTTCAGGCGCTCCTCGAAGTCACCCCGGTAACGGGAACCGGCGACCAACGAGCCCAGGTCGAGGGTGTAGAGCTGCTTGTCCTTCAGCGTCTCGGGAACCTCGCCCCGCACGATCTGCTGGGCCAGCCCCTCGACGACGGCGGTCTTGCCGACGCCCGGCTCACCGATGAGGACGGGGTTGTTCTTCGTCCGGCGGGACAGCACCTGCATGACCCGCTCGATCTCCTTGTCCCGGCCGATCACCGGGTCCAGCTTGCCCTCGCGGGCGCTGGAGGTCAGGTTGCGACCGAACTGGTCGAGCACCAGCGACGAGGACGGGGTGCCCTCACCACGACCGGCGGTCTCGGCCGGCTCCTTGCCCTGGTAGCCGGACAGCAGCTGCAGCACCTGCTGGCGGACGCGGTTGAGGTCCGCGCCGAGCTTCACCAGCACCTGCGCCGCCACGCCCTCACCCTCGCGGATGAGGCCGAGCAGGATGTGTTCGGTACCGATGTAGTTGTGGCCGAGCTGCAACGCCTCCCGCAGCGACAGCTCCAGCACCTTCTTGGCGCGCGGCGTGAACGGGATGTGCCCGCTGGGAGCCTGCTGACCCTGGCCGATGATCTCCTCGACCTGCTGGCGCACGCCCTCCAGGGCGATCCCCAGCGACTCCAGCGCCTTGGCGGCGACACCCTCACCCTCGTGGATCAGGCCCAGGAGGATGTGTTCAGTGCCGATGTAGTTGTGGTTCAGCATCCTGGCCTCTTCTTGGGCCAGGACGACAACCCGCCTCGCGCGGTCGGTGAATCTTTCGAACATTCGCACTCCCTGACAGCGGCGACAGCGGCTTCCAACTCGCCCCAGGCAGTGACACGCAGCCCCACTGGCGCTCTGCGACGAGGTCGGCACCCTACGACCACTGTAGTAGGCATTCTCGCTGCGGCGTGCTTCCGTTAGCTCCGGAAAGCGGCCGTCACACGTCCGACAGCGGGTTCAACGGGCCGGGGCCGCCCTGAATTCCTGGTCACGCTGGGTTGTGCCGGCTGTCCGCCCAGAGCGAACACGCGGTCGCCACCGGCGCGCGCGTCCGACCTCGGGTGGCCCGAGCCGCCGCTCGGTGCCCTGGCGGACCCGCCGTCCCGGCCCGACTCCCGGCGGGGAGCCCCGTGCCGCTGGACCCCGGCGAACGCGCTGGCGGTACCGGGTCGCGCACCACGCCACCCCTCGGGGATAAGGTTAGGCAACCCTGCCCCGGCCGCCGGGCGGAACCGAGGAGGAACAGCCGGCCGCCGGGTACCCGGGAGGACAGGGCCAGAGGAGACGAGGAACCCATCGGGTGAACCAACACCAGGTGGCGGAACGAGCCGGAGGTGACGTCGTGAGCATGCTCACCCGCGTCCGGGCGGGTCACCGGAGCGCTCCGCCCGCCCCCGAGCCCGGCACGACGATCGCCCACTCCATCGAGGCGACGCGGGCTCCCAGCTGGATGGCCCTGCGCTTCGGCGCCCCACCGGAGGAGGGGGAGACGTGGGTCGGCTGCGCGCGGGCGCTCGCCGACCCCGGGTTCTTCCCGTCCTGGCAGGCGCGGCTCGGCGACTGGCTACGGGAACGTTTCGGTGAGTCCCCGGACCGCACGACCTCCGGGTACCTGATGAGCTGGTACCTGCACGCACCGGGGTTCCTGGCCGGCATGCTCTTCCACACCGCCCGGCGGGTTCCGCACCTCCGGCCGGCGGACCTGGCGTTCCGGCTCGCGGACTCCCGCCCGCACGTCGACGGCGTGGCCCTGCTCAGCGAGGGGTTCGCCTGCCTGCCCGACGACCCGGCGGCCGGTACGGCGCGGGCCACGGTGGTGGCCGACGAGCGGGCGCTGGCCGCGCTGCTCCGCGCGCGCTTCGTCGACCACGCGGCCCGGTTCGTCACGGCCTTCGCCCCCCACACCCGGCTCGGTCGCCGCACCCTGTGGGCCGCCGCGACGGACGTGCTCGACACCGCCCTCTGGAACGCGGGGCGGCTGGGTGGCGACGAGGGGGCCGGCGTCGGCGACGCCTCGCTGGTGCTCGGGTGCTCGGACACCGACCCCCTCACCTCGGGGTCGACCCTCTACTCGGTGACGGGCGAGGACAACGGCCAGCACTGGACCCGACGCCGGCAGAGCTGCTGCTTCCACTACGCGCTCCCCGGGGTCGAGCGGGCCTGCGTGACCTGCCCCCGGGTCTCCGACGCGGAACGGGCGGACCGGGTCCGCCGGGGTGGCGACTGAGGAGGTACCCGGCTGGGGAGCGGTGGCCGTTCCGAACCGGCGGTCGTGACCGTTCCCCACCCCCTGAAGCTCGGGATGCGCTCGGGCCCGGCCGGTGGCGCTAGACGGTCGTGCGATGGCGTGCCCCGACGGGCACCACCAGCGGCGTCCCGGACACCGGGTCCTCGATGACCCTGGCGTCGAGCCCGAAGACGTGGAACAGCAGGTCCTCGGTGAGCACCTCGGCCGGTTCCCCCTCGGCGACCACCTCACCACCGCGCATCGCGACCAGTCGGCGCGCGTACCGGGCGGCCAGGTTCAGGTCGTGCAGCACCATCACGACCGTTCGTCCCCTGGTCGTGTGCAACCGCTCCACCAGGTCGAGCACGTCGATCTGGTGCGCGAGGTCCAGGTAGGTGGTGGGTTCGTCGAGCAGGAGCAGCTCGGTGCCCTGGGCGAGCGCCATCGAGATCCACGCCCGCTGCCGCTGCCCACCCGAGAGTTCGTCGAGGGCCCGATCAGCCAGCCGCTCCATCCCCGTCATGCGCAGCGCATCGGCGACCGCCTCCTCGTCGGCGGAGGACCACTGGCGGTACCAGGACTGGTGCGGGTGCCTCCCCCTGGCCACGAGGTCCGCCACGGTCAGGCCGTCCGGAGCGGTCGGTGACTGCGGGAGGATGCCGAGGACCCGGGCCACCTCGCGAGTCGGTAGCCGGTCGATCCGCTTCCCGTCGAGGAGGACCGTGCCCTCGGCCGGGGTCAGGAGCCGGCCCAGCGCCCGGAGGAGGGTGGACTTCCCACACCCGTTCGGGCCGATGACGGCCGTCACCGTGTTGTCGAGCACGTCCAGGTCCAGGTCGTGGACCACGACCCGCTCGCCGTAGGACAGCCGCAACGACCGCGCGCCCAACCGGGCGTCCGGTGGACCAGGTCGGTCATGGGAACGGGGCCGCGCCGGGACCGGCCTGGTCATGCTCCCCCCTCCCGGACCCCGCCACCGCCTCCTCCGGCGACAGCGACCAGCCGTCCCCGAGGGGTGGACGCACCTCGCGCGTCCCCGGCGTCACACCGAGCCGGCCGAGGTAGCTCGTGGCCGGGTGCCCCCCGCACCGGCGAAGCCGCGAGCCGGGTGCTCCGGCCCGCTCCACACCGGGATCGGTCGACCGGCAGGGCGCCCACGGCGGTGGTCCCACCCGCGCCAGGACCCGCGAGCTCCTCCGTGTTCACGCGGGACTCGGCACCGACCAGGAGTCCGGAGGCGGCGCGGGCGGTGGGGAGGCGGCGCCGCCGGCCCCCGACCCGCCCACTCCGGGGAGTTGGGGGACCGACTGGCCCCTCGGCCGGGGTCGACGTGCCCCGATGCCCCGGTGCCCGCACGCCGTCTGGCGCGTGGGGCCCCGTTCCGACCAGGACCAGCCTCGGTCGGACGGCGTCCACGACGGCGACAGCCGGCGGCGGGCTACCGCCGCGGGTGTCCGAGGTGGACGTGGCGTGCGCCCGTTCGCGAGTGGACGCGACCGCCGGCGTCCCCCTCCCGCCCCACCTCATGCAGCCCCCAACCCAGCCGACGTCGTTGGTGAGGCGAGCCTAACCGAACACCACGGCCAGGTGGAGCGCGCTTCGCCCCAGCGGGCCCGTGGAGCAGGGCCGCTGGGGCGGTCGACCTCCGGTGGCGATCAGTTGGCCTTGTTGTAGGCCTCGAGCACCTCGGCGGGGATCCGGCCCCGGTCCGAGACCTCCATCCCCCGCTTCCGGGCCCACTCCCGGATCGCCTGGTTCTGCTCGCGGTCCGCGGTGGTGGTGCTTCCGTTGCTCCTGCCGGCGGGCGCCCGACCAGCGGAGCGACGACGACCACCGGAACGCCGGGCGCCCTGGACGTAGCTCGCCAGCGCGTCGCGGAGCTGCGAGGCATTGTTCGACGAGAGGTCGATCTGGTAAGCGACACCGTCGAGTGCGAAGTCAACGGTCTCCTCGGCCTCGCTGCCGTCGAGATCGTCGACCAAAGTGACGGTTACCTTCTGCGCCATAGTCCTCGTCCTTCCCCAAAAGCTCGCTCAAGGCTCAGGCCCGCCCTGGGCCAGCCCATGCCGGTTCCGGGACCAGTTCCCGACCGGTAGCGACGATCAAAATACCGGTCGCTGTTCCCACAATACTAACGCGTTTTCGGCAGGACGCACTCCGCCTAGCGAGTTCCGCTGGTTCATTCAGGGCGCACGAGCGGGAAGAGGATGGTCTCTCTGATGCCCAGTCCGGTCAAAGCCATCAACAGGCGGTCTATCCCCATTCCCGTGCCGCCGCTGGGGGGCATTCCGTACTCCAGTGACCGCAGGAAGTCTTCGTCCAACTGCATGGCCTCCTCGTCCCCGGCCGCCGCCAGCCTGGACTGTTCCCGCAGCCTTTCCCGTTCCACGACCGGGTCGACCAGTTCCGAGTAGCCGGTCGCCAGCTCGAAACCCCGCACATACAGGTCCCACTTCTCGGCGACCCCGGGCTTGTCCCGGTGCTGCCTGGTCAGCGGGGAGGTTTCCAGCGGGAAATCCCGGACAAAGGTCGGCTCGTGCAGCGCCGAGCCCACCAGGTGCTCCCACAGTTCCTCGACGAGCTTGCCGTGGCCGAGCTTCGCCCCGCCGCCGGCGAGGTCGAGTCCGTGGGAGGCCGCCAACGTCCGCAGTCGCTCGGCGGGGGTCTCCGGGGTGACCTCCTCCCCCACCGCCTCGGCGAGGGACTCGTACATCGTCAGCGAGGCCCACTCACCGGACAGGTCGTACTCGGAACCGTCGGCGAGCGTGACGACCTGGGTGCCGAAGACCCTGGTCGCCGCCTCCTGCACGAGCTCGCGGGTCAGGACGGCCATCGTGTCGTAGGTGCCGTAGGCCTCGTAGAACTCCAGCATGGCGAACTCGGGCGAATGCGAGGAGTCGCTGCCCTCGTTCCGGAAGTTGCGGTTGATCTCGAAAACCCGCTCGATTCCGCCGACCACGCACCGCTTCAGATACAACTCGGGGGCGATCCGCAGGAAAAGGTCGATGTCGAAGGCGTTCGAGTGGGTGAGGAACGGCCGGGCCGCGGCCCCGCCGTGGAGGGTCTGGAGCATGGGCGTCTCGACTTCGAGGTAGCCGCGCTCGTGAAAGGACTCGCGCAGGGAGCGCACGACGGCGGACCGGGTGCGCACGGTCTCCGCCGCCTGCCGGCGGACGATGAGATCCACGTAGCGCTGCCGCACCCGGGTTTCCTCGGCCAGGTCCTTGTGGGCCACCGGCAGCGGCCGCAAAGCCTTGGAGGCCATTCGCCATTCGTCCACCAGGACGGACAACTCGCCCCGGCGGGACGTGATGACCTCGCCGGAGACGAAAACGTGGTCGCCCAGGTCGACGTCGGCCTTCCAGGCCGACAAAGCCTCCTCCCCCACCTGCTTGAGGCTGACCATTGCCTGCAGTTCCGCGCCGTCACCAGCACGGAGCGTGGCGAAACACAGCTTTCCGGTGTTTCGGAGGAACATGACCCGGCCGGCGACCCCGACAATCCGCCCAGTCGAGGTATCCGGGGCGAGATCGGGATTCTCCGCGCGCACCTGCCCGAGGCCGTGCGTGACGGGGAGCGAGACCGGATACGGCTCAATACCGCTCGCAAGCATCCGCTCCCGCTTCTCGCGGCGCACGCGCATCTGCTCGGGAAGGGTGTCCTCGCTGGTCACAGTGTCATTGTCCGGCTGCCCGTTCACGGGGGAACAGACTACGTTCCTTCCCCCCAATACCCCCAACCGGATACCATCCTCGGAGTGGATCACGTTGCGGTCGGCTCAGCCGACGATCGACGCTCGGACGCCGCGCAGGCCGGTTCCTTCGGGCAGGTGGCCCAGGACTACGCCGAGCACCGACCCGGCTACCCGGACCTGGCGGTGCGCTGGGCCCTCGAGCCGGTCCTGTCCAGACCCCACGTCGCCGTGCTGGACCTCGCGGCGGGCACGGGGAAGGTGACCCGGTCCGTGCGCGGGCTCGCCGCCGAGACCGTCGCGGTCGAGCCGGACCCCCGGCTCCGCGCCGAGTTCACCCGGCGGGTGCCGGGCGTGCGCGTCCTCGACGGCAACGCCGAGGCCCTACCCCTGCCTGACGCCTCCGTCGACGCGGTCACGGTCGGCCAGGCCTTCCACTGGTTCGACGCGCCGAGGGCGCTGGACGAGATCGCCCGCGTCCTGCGGCCCGGCGGGGTGGTGGCGGCGCTCACCAACTACAACGACGACCGGCGGGAGTGGGTGGCGGGTCTCCAGCGCACCGGGATCCCCAGCCCGGGAATCAGCGAGGAGGACCCGGACTACGTCCCGGCGCACCCGAGGTTCGCGCCCGTGGAGACCGCCCGCTTCGAGCACGCCCACCGCCGCACGGCCGAGTCACTGGTCCAGATGATCTCCACCCACTCGTGGGTACTGGTCCAGGACCCGGACGAGCGAGAACGGATGCGGGCCGAACTCCGGTCCTACCTCGCCGGGAGGCCGGAGACCCGCGAGGGTGAGTTCGACCTCCCGCAGATCGCCGTCGTGAACCGGGCGGTCCGCCGCTGACGGGCGGCCGCCCGGCTGACGAGTGGGCACCGGCTCAGTGCACGTTGCGTTCGTAGAACAGCCTGAGACCGACCAGGGTGAGGTCGGGGACGTGGTGGTCGATCGTCTCCGTCTCCCCCACGATGAGCGGCGCCAGTCCCCCCGTCGCGATAACGGTGACCGGTGTGTCCCCACCCGACCTGAGTTCACCCACGATGCGGCGCACCAGGCCGTCGACCTGGGCCGCGAAGCCGTAGAGGATGCCGGACTGAAGGCACTCGACGGTGTTCTTGCCGATCACCGCCCTCGGCCGGACGAGCTCCACCTTGCGGAGCTGCGCCGCGCGCGAGGCCAGCGCGTCCACCGAGATCTCCATCCCGGGCGCGAACACGCCGCCCAGGAACTCCCCCTTCTCGGAGATGACGTCGATGTTGGTCGAGGTTCCGAAATCGACGACCACGCAGGCGGTCCCGTACAGGTGGTGCGCGGCCAGGGTGTTCACCACCCGGTCACCGCCGACCTCCTTGGGGTTGTCCACGAGCAGCGGGACACCGGTCCGCGCCCCCGGCTGCACCAGCATCCGGGGCACCGACGAGTAGTACCGGCCCAACATCACCCGGAGTTCCCGGAGCACCGCGGGCACCGTGGACAACGCGGAGACGCCGGTGATGCGATCCGCGTGCTCGCCCAACAGCCCCCGCATCGTCAGCGCCAGCTCGTCGGCGGTCATCCTGGCGTCGGTACGCATCCGCCAGTCGCGCAGCAGCGTGGCGTCCGCCCCTCGGCCGGTGTACAGGCCGAGCACGATGTTGGTGTTACCGATGTCGATGGCAAGCAGCACCGGTTGCCCCTTCTCCCTCATCCACGGCTACGAGCGGTCTCGCTCAGCCCTCGGTCTGGAGCGGCGCGTCCGACCGCGCCGCGTCCGCGGTCTCCCCGGGCTGGTCCTCGGAGCCTCCCGCCACGACCGCCCCAGACCGCAACCCGTACCCCTCGGGCACTCCGGCGGGGTCGCCGTCCTGTCGCAGCACCCGGTTGTCGCCGTCGACGAAGAGGACCCTCGGCGGCCGGGTCCTCGCCTCCTCCTCGTCCATCACGCCGTAGGCGATCAGGATGACGATGTCGCCGACGTGCACCAGGTGCGCCGCGGCGCCGTTGATCCCCAGTACACCCGTGCCGCGCTCACCCGGGATGGCGTAGGTCTCCAGCCGTGCGCCGTTAGTGACGTCCACGATGGTCACCAGTTCACCCGGAAGCAGGTCCGCCGCCTCCATCAGATCCTCGTCGATGGTCACCGAACCCACGTAGTGCAGGTCGGCCTGGGTGACCGTCGCGCGGTGGATCTTGGACTTGAGCATCGTGCGGAACATGGAGGTGCCCTCTCTTTCCTGCGGTCGGCTCGGTTCAGCTGGCGAACGTCGTGCCCGAGGCGGTGTCGTCGGGCCGAGACAGCACGAGTGGTGCGTTGTCGATCAGTCGGACGTCACCGATCCGCGCGGCGACCAGCAGGCGGGCACTGCCCTCCTCGGGCGCCGGTTCCAGGTCCGGCCCGCGAAGCTCCAGGTAGTCCACGTCCAGCGCGGGTTCGGCCGCCAGCACCTCACGGGCGGTGGCCAGCGCGGTCGCCGCACCGGCGCCGGCGGTGTGCACGGCGGCGGTCAGCGCGGCGGAGAGGGCGACGGCCGCCGCGCGTTGGTCCTCCCGCAGGCGGGCGTTGCGGGACGACAGCGCCAGTCCCCTCGGTTCCCGTACGGTCGGAACGCCCACCACGGCCGTGTCCAGGTTGAGTTCGCGCGCCATCCGCCGCACCAACACCAGCTGCTGGTAGTCCTTCTCCCCGAAGAACGCCACGTCGGGCCGCACGATGTTGAACAGTTTCGCGACGACGGTGAGGACGCCCTCGAAGTGGCCGGCCCGGGCCGCGCCCTCCAGCTCGTCACCCAGCGGGCCGGGACGCACGCTCACCGAACGGCCGTGCGGGTACATCCGCTCGGCGGTCGGGGCGAACACCAGCTCGACGCCCTCGGACCGGCACACCTCCAGGTCCGACGCGAGGTCCCTCGGGTAGCGGTCGAAGTCCTCGCCGTCACCGAACTGCAACGGGTTGACGAAGACCGACACCACGGTGACGGAGTTGGGCACTCGACGGGCGTGGCGGATCAGCTCGCGGTGACCGGCGTGCAGGGCACCCATCGTGGGGACCAGCGTCACCCGCCGGCCGGCGGCACGCAGCGTCCTGGTGACCTTCGACAACGCCTCCACGTCGGTGTGGGTGGTCAGCTCACCGGGGCGGAACGGGCGGGCGGCGGGATCGGTCGTCATCGGTCCTCCTCGTCGAGTGACGTCCGCACGTCGTCCGCCACGTGGGGCGGCAGGAGACCGGCCCGCTCGGCGCGATCGGCGGTCCGCGCTGCCAACAGCCGGTAGGCGGGTTCGACCTGGGGCGCTGCCTCGGAGAGGACCTCCAGGTGCCGGCGGACGGTGCCGACGTCACCCCGCGACACCGGGCCGGTCAACGCGCGGTCCCCGTGCCGGAGGGCGTTGTCGAGAGCCGCTCCGAGCAGCGGCCCGAGGAGACGGCCGGACTCCCGCACCCCGCTGGACTCGAGGAGCTCCAGGCAGTCACCCACCAGCGTCATCAGGTGGTTGGCCCCGTGGGTGAGCGCCGCGTGGTAGAGGGGACGAGCCTCCTCTGGCACGCGAACGGGTTCGGCTCCGAGCTCCACGACGAGCGCCTCGCCCACGTGCCAGCCCATTCCGCCGGCCGTGCTGGTGCTCGGCTCGTCGGGTTCGCCGGCGGCGGCCGTCACCGCCACCGAACAGGTGGCGAGCCGTTGCAGGTCCTCGGGACGTCCGGTGAACGTCATGGCGGGGTGCAGCGCCACCGGGAGCACCCCGACCTCGGCGGCGGGACGCAGGACCGACACCCCCAGCGCGCCGGACGTGTGGGCCACGATCTGCCCCGGACGCAGCGACCCGGTCGCCACGAGACCGCGCACCAGCCCGGGGAGGACGTCGTCGGGAACGGCGAGCACCACGAGGTCGGAACGCCGAGCCACCTGGTCGGGTGGTAGCAGGGGAACATCGGGGAGCAGTTCCTCGGCCCGGCGGCGCGAGGCCGAGGAGACGGCCGAGGCACCGACGACGACGTGCCCGGCCTTGGCGAGGGCGGCGCCGAGCACGGCGCCGACGCGTCCCGCCGAGATGACTCCGGTCGCCAGCCTGGCTGGCCGACCTCCGAGGCTGGCATCCTCGCCAGCGGCCCCCGGGACCACAGCGCTCATCGTGCGCGACTCCTTCGTTGTGTTCCAGTCCCGACTCCCGTCGGGTACCGGACAGCCGCGAGGGTAGCCGCTGGGAGGAGCCCGGTCCTCGGTCGGGTGAGCAGCTTCACGCCGGCCCCGTGCGGCGCCGCTCCCCGCTCCCCGATCAACGCTCAACGCCGGGGGCGGGTCCCCCTCCGCCTCTCGGCGTGGGCGGCCCTGGTCGCGGCGCTGCGGACGAGGCCGTCTCGGACGGCCTCGGCGCGGGCGCCGAGCAGCACCCCGACCGCCTGCGCCTGCCGTCGCGCGGCGTTGGGCACCGGGAGCCCCTGGGCGACCCGGTGCCGGAGGAACGCGAGCTCGGTGACCGCGTGCTGGTACTCGCGGACCGCGCGGGCGGCCTCCGCGCCCGCCCGTTCCCGCACCGCCTTCCGCCACGCCTTCCGGCTGGGCAGGCTGGAGAGCAGGGTCACCTCGCCGGGGGCGATCCAGCCCTCCTCGGCGAAGCCGGGCAGTTGGGCGACGACGGTCCGTTGTTCCCGGCGTCGTTGCCACAGCACGAGCACCAGCGTCGCCACGAAGATCGGCACCATGACGACGAAGTAGGTGTCGACGAAGGTGGCGCCGCCGCCCAGCGTGGCCGCTCCGTTCCACACCGCGTGCAGCAGGACGGCCAGGACGTATCCCACGAGCAGCGCCGTCGTTCGCACCCACTTCTTCCTCGACCCGGCCGCGATACCGACCCCGATGCCCACCATGGCGCTGAACAGCGGGTGCGCGAAGGGGGTGAGGATGCCCCGCAGCACGAAGACGGCGACGATACCGCCGGTGAGGTCACCGAAACCGCCCTCGCGGAAGGCCAGGCCGAAGTAGTTGATGTTCTCGGTGAAGGCGAACCCGATGGCGGTGACACCGGAGTAGACGATGCCGTCCACGATCCCGTCGAACTCCACCCGGCGGCGGAGGAAGACCCCGACGACGAACAGCGCCTTGGCGGCCTCCTCGACCAGGGGCGCCGAGATCACGGCCGCGACGACGTCACCACCTCCCGTTCCGAGCAGGGACTCCCCGACGACCTCGGCGGTGTTGTTGATCAGCAGGGCGCACCCGGTGGCCCCGCACGCACCCCACACGAACGCGGCGAGCAGCAGTTTCGGCGGTTCCGGCTCCCACCGGTCGATCCACAGGAAGGCCGCCAGCACGGGGCCGACCGGGAGCAGGGCCAGCAGGGCACCGACGATCACCGGGACGAACCCGACCCTGGCGGTGGCGACGCCGAGCAGGGCGAGGCCGGACACGCCCAGCAGCACGAGCACGACGACCGGCCACAGCAGGACCCGACGTCGCTCCAGGCGCGCGCTGGTCAGGTGCCGAACCGGCGTCCGCTCGTCGATCGCCACGCCGCCCACCTCGCGCCAGGGCCGGCGGCGAGCGCCCGGCCGGTAGTCGAAGGACACGGCCTCCGGTCCTGGCCGTTCCCTTCCGAACCTTATTGGCGTTGGGCCGCTCGCGCCGCCGGGTTCCGCCCAGCCGAGGGCACCGCTGTCGGAGACTGTGCTGATGCTGGACTGGGAGCTGGCCTGGTCCCGTGCGCTCTACGGCCCGAACGGCTTCTTCGCGCGGGGCGAACGGCCCGATGGGCACTTCCGCACCTCCCCCCTGGTGGGGCCGGCCTTCGCCGAGGCCGTGGTGACCCTGCTCGACCGAGTGGACCACGCGCTGGGCCGGCCAGCCCGGGTGGACTTCGTCGACGTGGGGGCGGGTGGCGGCGAGCTCGCCGAGGAGGTTCGGGAACGGGCCCCGTCCAGGCTCGCGGACAGGGTGGTCGTCACCGCCGTCGACGTGGCCCCGTCGCCCGCATGCCGGGTTCCGGGCGTGGTCTGGCGCTCCACGCCGCCGCGTCGGGTGGTCGGCCTGGTCGTGGCCAACGAGTGGCTGGACGCCGTTCCCTGCCCGGTGCTCGTGCGACGCGGCGGTCGGTGGCGCCGGGTCGGGGTGGATTCGGCGGGTCGGGAGGCGGTGCTCGACCCCGTGGACGCCGCCGTCCGGGCGTGGCTGGGGCGCTGGTGGCCGATAGGTCGGCGCGCGCGGGGCGGCGCGGAGCTCCGGGCGGAGGCGGGGACACCTCGGGACCGCGCGTGGACCTCGGTGGTGCGCGGGGTCCGGGCCGGGGTCGCGGTGGCCGTCGACTACCACCACCGGCTGGCCGACCGGCTCGCCGGTCGGGTGGATGCCGGAACCCTCGCCGGCTACCTGCGCGGACGACGGGTGGCCCCGATCCCCGACGGTTCCCGCGATCTGACGGCCCACGTGGCGCTGGACGCGTGCGCGGCGGCCGTCCACGCCGGGGTCGGGGGGCCGCTGCGCACCACGTTGACCACCCAGCGGCGGGTGCTCGCCGACCTCGGTGTGGTCCGCGCGGCCCCGTCGCCGTCGCTGGCGGCCACCGACCCGTTCGGCTGGTTGGACGCCGCCGCGCGGAGCGGAGGCGTCGCGGAACTGACGTCTCCCGAGGGGCTCGGGGGCTTCGGCTGGTTGGTGCACGAGGTGGCCCTCCCCGTGCGGGTGCTGGCGTCCGGGGACCGGAGCCCGGTCCACTGAGGCGCGCGCCCGGGCGAGGCTCCGGACCGCCGCGAGGGGCACCGGGCCGACCGGTGCGTCGAGGAGGGCCGGGGAGCCCTCGTCCGATGCCCCGAGCCACCTCGCGTCCCGGGTCCCCCTCCCGACCACCGGGAGGGCGGGCGGGGGTGGCGGTGCGAGCATGGGCGCGTGTCTGACCAGATGACAGTCGGCGTCGGCGCGGGAGCCGCCCACCTCGGGGTGGACCGCGTGGTGGACCTGGGTCCCCTCCACCCGGCGGCGCACGGTGCCTACCGGCTCCGGCTCGCGGTGTCGGGACCCGCCGACGACCCGGTGATCACCTCCGCCACCCCGCTCGTGGGGCACCTGCACCGGGGTGCCGAGAAGCTCTTCGAGGTCCGCGACTACCGGCAGATCCTCGCCCTGGCGAACCGGCACGACTGGCTCGCCGCCTTCTGCAACGAGATGGCGGTGGCGATGGCGGTGGAGCGGATGCTGGGCATGACGGTGCCCGACCGGGCGAGCTGGTTGCGCACCGCCTTCTGCGAGTTGAACCACGCCCTCGCCCTGGTCGTGTTCCTCGCCCCGGTGGCCGAGGCGGGTGGCCGGGGACCTCGGCACGTAGCCGCCCGGGATGGACTGGTCAGGGCGCGGGAGTCCGTCCAGCGGGTCCTGGAGGAGGCGGCGGGCGGACGCATCCACTTCATGGCCAACCGCGTCGGCGGGCTCCGCGAGGACGTGCCGGCTGGGTGGCGGGACGGAGTCCGCGCCGCATTGGACGTGGTGGCGAGGGGGCTCGACGCCGCCAGGTCGGTGACGGTGTCCGACGGGGACTTCCGACACCGGCACCGCGGGCTCGGCGTCCTGACGACGGGTGCGGCCCTGCGGCTGGGTGTGACCGGCCCGGCGGGTCGGGCGGCCGGCGTCGACCTCGACCTGCGGCGGGACGATCCGGGACCGGCCCACGCCGAGCTGGGCGTCACCCCCCGGCTGGGGACGCGGGGCGATGCCCTGGACCGGGTGGAGTGCATGCTCGACGACGCGGACCAGGCACTGCGGCTGGTCCGCTCCTGCCTCGACCGGCTGCCACCCGGGCCGGTGAACCTGCGGCTGCCCAAGGCGGTCAAACCACCCGAGGGGTCGGTCTACGTGTGGACGGAGGCACCGCTGGGGGTCACCGGCGTCCACCTGGTGTCCCGGGGCGACCGGACCCCCTGGCGGCTGAAGTTGCGGACGCCGTCCTTCAACAACGTCCAGGCGCTCTCCCCGCTGCTGGTCGGCTGCCGGGTGGCCGACCTGCCGACCGTGCTCGCCTCCTTCGCGGTGGTCGTCGGGGACATCGACCGCTGAGCCGCCGTGGTCAGTTCCCGCGCCGACGGCGGCGGCGCGGTTTGTCCTCCCCGTAGGCGGCCAGCAGCTCGCTGACCGACCGGCCCGAGGCGTGCGCTCCCGCGTCCTCCGGCTCGGCGGGCGGTTCGCTCGCACTCTCCCTCGGTCCCGGGGTCGTCTCCTCGGCGACGTCGGGCTGCCAGGCGTCCACCGCCTCCCAGGCCGGGGTGTCCTCGACTGCCTCCGCCTCCGCCGCGGCGGCGACCGGCTGCGCCTTCGGGGGCGCCGGCGGCTGCGCCCGGCGCGGCCGCTGCGGGCGGGGGAGCTGCCGGGTGGCCTCCTCCCGCTGTTGCCGCTGTTGCCGCTGTTTGCCCTGCGGGGCACGCCGAGGGGCGGGGCGGGCCACCGTCTCCGGCTCCGCCGGCGGGCGCGGCGCTGGTCCCCGCCCTCCTGGTCGGCCGGGTGGGCGCGGCGGGCCACCGGCGGCGGACCGGGGGTCCTCCCCGGGCTCGAGTGGCCGGGCGGGATGGGGGACGCGGGTGGTAGCCGGATCCGGGCCGGCGGGTGGCTGACGCTGTTCGGCGGGGACGGGGGGTTCCCCTCGGGGGGAGCTGGGTGCCGGCTGGGGCCGACGCGGCCCGGGCGCTCCGCCCCGGGGGTGGTCCGGGTTCGGGGGCGGCGGGCCCTGGTCGTTCGGGTGTCCGGCGGGTGCCGGGCCGCCACGCGCCGGCCTGCCCGGCGCGGGAGGACGACCCGTCGGAGCACCCCCGATCACCTGGGTCCGGTCGGCGGGAGCGGGAGGCGGGTTCCCCTGGCGGGCCTCGGGATCGGGCTCGACCTCGGCGGCGTCATCGACCGTCCGCGCACCGACGGCCAGCGCGCGCACGGGAGGGTTCTCCTGCTCACCCGAGGAGATCACCCGCCCGCCCTGGTCGGACAGGGAACGCACCCTGGTGGACTCGGCGCGGAGCGCCACCCGTTCGACGAGGACGTCCCCGCCCAGCAGGGACTCCAGGCCGCGGCGCAGCGTCTCCAGCTCCCGCTGGAGACCGGCCAGCTGTTCCTGGGACTCCGCTCGCAGCTCGTCCTCGACCTGCCGGCGGGTCTCCGCTTCCAGGTCGAGTTCGTACTCACGACGCGCGGCTACCTCACGTTCCAGCTCCAGCTCGTAGACCCGCCGCAGTTCCTCGGACTGGTCCGCCCGCTCGGCAGCCTCCCGCCGGTACCGGGCGGCGGCGAAGGCACCGAACAGCGCGGCCCACAGTCCCGCGACGATGCCCAACCGCAGGAGGCGGGCGTCGTCGCTGAGCAGCAGCAGCACCGTGGCACCGAGGGCCAGCGCACAACCGCCGATCCAGAGAACGGGACCACGGCCGACACGGTTCCGCTCGTCATCCGAGCCAGAGAGGCCGCTCATAACGCCACACGGTACCGGTCGGTAATCGAACCGAGACCTGTGGCAGGGGGCCGCTCCCACGACCTCGGACGAGCGGGAGGACCCGCCGACGGGGGGTTCGTGCCGGCGGGAACGGGGGCAGCGTCCTGCCTCCGGCCGCACGGCGGTACGCGCCTAGTCGTCATGGTTGTTCCGGTCCTCGTCGGAGTCGGGGTCTTCCGGCGCTCGGCAGCAGTGCTCCAGCCAGAGGGCGGCCGCCGCGAGCAGTACCGCGCAGGCGATGCCGATCAGCGACGTCACCTGGTCCCCAGCCGCGGCGTCGAAGTCGCCCCGGTGCGGTGAGACGTACAGCAACACGGCCAACCACGCCCCGAGCATGATCACACCCAGCAGCGAGGACGCCTTCGCCAGGGCCACCGCACGCGCCGCGAACAGGGCGAGTTCCCGGGGAACGGCGCCTCGCCGGTCCCGCTCACGCACCCGGACGCGGATCGAGAAGCCCAGGACGGCCTCCACCGCACCGATGAGCACCAGGGTGGCACCGGCGAAGGTCGGCAGGCGGGGCAGCGACGAGTAGAAGAGGGTGAGCAGCAGGTAGACAACGAGCAGGCTGCCCAGTCCCACGGCCAGCAGGTCGCGGGCCCTGGTGAATCTCATCCGCCCGCCTCCTTCATCCTGGTCGTCGCACGGCCCCAGTCTCTCAACGCCCGGCCGCTCCGCGCAGATCCAGGTCCGAGCGGACCGCGACCCCCGCCCTGGACACGCTCCGCAGCAGTTCCCGCACGGGTCCGTGCCCGGGCAGGACCGCCTCCGGTTGGACGTCGAACCACGGCACCAGCACCGACGCCCGACCCGGGGTGCCGGGGTGGGGCAACACCAGCTCCGGGTCCTCCGACCGGACACCGTCGACGGTCACCACGTCCACGTCCAAGGTGCGCGGGCCCCACCGGACGGTGCGCTCCCGCCCAGCGGCCTCCTCCAGCTCCCGAGCCCGGTACAACCAGCCCCACGCGTCCACCCCGGCGTCGTCGACCACGACCACGGCGTTGAGGAAGTCCGGCTGGTCGGTCACTCCCCACGGGGCCGTCTCGTAGACGGGGGACACGGCGACCACGGCCGCGCCGAGCCCGGTCACCGCGGACCGGAGGTGCGCGAAGCGGTCGCCGAGGTTCGAGCCCAGCGAGAGCACCGCCCTGGTCACTAGGCTCCCCGGCCGCCGCGCCTCGACCTGCGGACGGTCACGGCGACGTCGTCGAACGGCACCGCGATCGGCGCCGAGGGCTTGTGGACGGTGGCTTCGACGGCGTGGACCCGCCGGTCGGCCATCACCTCGTCGGCGATCTGGGCGGCCACCCCCTCGATCAGGTTCCTCGGGGGGCCGCCGACGACGGCGACGATCCGCTCCGCCAGCGCGCCGTAGTCGAGCGTGTCGCGGAGATCATCGGTGGCCGCCGCGCCGGAGAGGTCCACCCACACGGTCAGGTCGACGACGAAGTCCTGCCCGTCGCGCCGCTCGTGCTCGAAGACCCCGTGGTGTCCCCGCGCCCGGACCCCCGTCACCCTGATGCGATCGGTCACCGCGCACCCCCGGCACGCCAGGCCCGCTCCACGGTGATGGCGTCGAGCGAACCGACGACGTCGTGCACCCGCACGCCCCACGCCCCGGCCGCGGCCGACAGGGCAGACACCGTCGCGGTGGCCACCTCGCGGCCGGCGGGGGGGCGGGGGGTCCCGTCCGGGTCGGCGAGCGCGGCTCCCAGGAACCGCTTCCGCGAGGCGCCCACCAGCACCGGGAACCCGAGTTCCAGCAGGGCGTCGAGCCGGTTGAGCAGTGCCCAGTTGTGCTCGGCGTTCTTGGCGAACCCCAGGCCCGGGTCGAGCACCAGGGACTCGGGGGCCACGCCGGCCGCCACGGCCTCGTCGACCCGGGTGAGGAGCTCGGCACGCACGTCGGAGACCACGTCCTCGTAGCGGGCCAGGCTGTTCATGCCCTTGCTGTGGCCCCGCCAGTGCATGAGGATCCAGGGGGCTCCCGCCTCGGCGACCACCCTGGCCATCCCGGGGTCGGCCAACCCACCGGAGACGTCGTTGACGACGGCCGCGCCGGCGGCGAGCGCGGCCTCGGCGACCGTCGCCCTGGACGTGTCGATGCTCAGGGTGACGCCCAGAGCCGCCAGTTCCCTGATCACCGGTACGACCCTGGCGATCTCCACGTCCGCGTCGACGCGGGACGACCCTGGCCTGGTGGACTCGCCGCCGATGTCGATGATGTCGGCTCCCTGGCGGTGCATCTCCACCCCGTGGTGGATCGCCTGCGCCTGGTCGAGGTAGCGGCCACCGTCGGAGAAGGAGTCAGGCGTCACGTTCAGCACGCCCATCACGGCACAGCGGCCCGGCATCGGCAGCACCCGTGGAACGTGGTGCGTCTCCTGTACTAACACGGCGGATCGCTCCTCAGCTCGATGTCCGACCTGCCGCCATTCTGGCCGTGCCCGCACGGTGCGCGCACCGGTGCGGAGCGTTGCCCTCCCCTCAGCCCGAGCGCATCAGGTTCAGCGCCTCGGCGCGGGACGAGGCCGAGGTCCTGAGCAGGCCCCGAACGGCCGAGGTCGTCGTCCTGGCCCCGGGCTTGCGCACCCCGCGAACGGTCATGCACAGGTGCTCCGCCTCGATCACCACGATCACGCCACGCGGGGCGAGCCGTCGGACGAGGGCGTCGGCGACCTGTGAGGTCAACCGTTCCTGGACCTGGGGGCGCCGCGAGTAGAGGTCGACGAGCCTGGCCAGCTTCGACAGACCGGTCACCTGCCCCCGCTCGTTGGGGATGTACCCGACGTGGGCCACCCCGTGGAAGGGGAGCAGGTGGTGCTCGCAGTTGCTGAACATCGGGATGTCCCGGACGAGCACCAGTTCCTCGTGGCTCTCGTCGAACGTCTTGGACAACACCGTGTCCGGGTCGGTGTGCAACCCGGCGAACATCTCCCGGTAGGCCCGGGCCACCCGGGCCGGTGTCTCCACCAGGCCCTCGCGGTCCGGGTCCTCGCCACAGGCGATCAGCAGCTCGCGGATCGCCGCCTGGGCACGTGCCTGGTCGAACCGGCCGGGACCGGTCGTGGGGGCGACCAGGTCACCGTCCAGGTCCTCGAAGGTGCCGGTCACCGCTGCCCTCTCCGGAGGTCAGCGACCATCACCGTCCTCCTGGTCGTTCCTCGTCCCGCGCCGAGGGTCGTCGGGCTGCTCCTGCTGACCCGATCCCGCGCTGGGCCCCTGCTGCCCCGGCAACTCGTCACGGCTGAACCGCCGCGTGCCCTCGTCGCCGGTGTCCGGTGCCGTGCCGCCCTCGTCGGGCTTCTCGGCCCCGGAGGGTTCGCCGGCGGCGGGTTCCCGCGCCACCCCACCGCTCTCGCCCTCCGGAGAGGTGGACGGCTGCTGCTCCCAGTTCGGGTTCGTCCCGCGCTCCCAGGAGGGGGTCCACCCGGAGGACTGCGGCGTCCACGGCGAGGTCGCCGGCGTCCACCCGGGGGGCGCGCCGTAGTTCGGCGGGCCGGAGCGGCTACCACCGGCGGGTTTGGGGATGGGGCGTGTCGCCTGGTGGTTTGGGTGCACCGCCGGTTGCGGCGCGGCCTGGCCTCCCGGCCACGGCGCCTGCTGGGGTGGCGCCTGCTGCGTTGGCCCCTGGTCCGGCTGCCCCTCGGCCGGCTGGTCCGGCTGCTGCTGGCTCGGCTCCTCGACGGCGCCCGCGCCCTGCTCGGGAGCGGCCGGTCGCTCCGGAGCCGCTTCCACGGCCGGCACCGGGGGCCACGGCTCGCCGCGCTCCTTCGCCAACTCGGCCGGGCTCTTGATGGGCGGCTTGTCGGAGGGGGTGCGGTGACCGAAGTCGTTGAAGGCGGTGATCCTCGGCCGCTTCTCCACCCGGGAGAAGATGCGTTCCAGGTCACGCCGTTGCAGCGTTTCCTTCTCCAACAGCTCCAGCACGAGGTCGTCGAGCACGTCGCGGTAGGTGTTGAGAATCTCCCAGGCCTCGGTGTGCGCGGCCTCGATGAGCTTGCGCACCTCCTCGTCGATCTCGTGCGCGACCTCGAGGGAGTAGTTGGGCTGCGTTCCCATCGTGCGGCCGACGAAGGGGTCGCCCTCGTCCTTGCCGTACTTCACCGCGCCCAACCGGTGGCTCATGCCGTACTCGGTCACCATCGCCCTGGCGATCTTCGTCGCCTGGTCGATGTCGGAGGACGCACCCGTCGTGGGCTCGTGGAAGACCAACTCCTCGGCCGACCGCCCGCCCAGGGCGAACACCAGCCGCCCGATCATCTCCGACCGCGTCATGAGGTCCTTGTCGTCCTCGGGCACGACCAACGCGTGCCCTCCGGTTCGGCCTCGCGGCAGGATGGTCAGCTTGTAGACGGGTTCCAGGTCGGGCATCGCCCACGCGGCGAGCGCGTGCCCGCCCTCGTGGTAGGCGACGATCTTGCGTTCCTTGTCGGAGACGACGCGGCTGCGGCGGGCGGGCCCGCCGATGACGCGGTCGACGGACTCCTCCAACGCGGCGGAGGTGATCAACTGCCCCTGCTGCCGGGCGGTGAGCAGGGCGGCCTCGTTGATGACGTTGGCCAGGTCCGCGCCGGACATGCCGACGGTCCGCTTGGCCAGGGATTCGAGGTCGGCGTCCTGCGCCAGCGGCTTCCCCTTGGAATGCACCCGGAGGATCGCCTTCCGCCCCGCCAGGTCGGGGGCGGCCACCGGGATCTGCCGGTCGAAACGACCGGGGCGCAGCAGCGCGGGGTCCAGGATGTCGGGACGGTTGGTGGCGGCGATCAGGATGATGCCGCCCCGGGAGTCGAAGCCGTCCATCTCGACGAGCAGCTGGTTCAGCGTCTGCTCCCGCTCGTCGTGCCCGCCACCGAGCCCGGCGCCGCGCTGGCGGCCGACCGCGTCGATCTCGTCGACGAAGATGATGCAGGGTGCGTTCTGCTTGGCCTGCTCGAACAGGTCACGCACCCGGGACGCCCCGACGCCGACGAACATCTCGACGAAGTCGGATCCGGAGATCGAGTAGAAGGGAACACCGGCCTCACCGGCGACCGCCCTGGCCAGCAGCGTCTTCCCGGTTCCCGGCGGTCCGTAGAGCAGGACGCCCTTCGGGATCTTCGCTCCCAGCGCCTGGTAGCGGCCGGGCGACTGGAGGAAGTCCTTGATCTCGTAGAGCTCCTCCACGGCCTCCTGCGCACCGGCGACGTCGGAGAAGGTCGTCTTGGGCATGTCCTTGTTCAGCTGCTTGGCCTTGGACTTGCCGAAGTTCAGGACGCGGTTGCCGCCACCCTGGGCGTTGTTCATCATCCACAGCAGCAGGAGGAGCAGCAGGACCAGCGGGACCATGTAGATCAGCAGCTGGGTGAACAGGCTGTCCTGGTTGACGGTGGTGTCCCACTCGTCGATGCCCGAGGCGCCCCGCAGCGCGTCGACGATCTGCTCGGTGCCACCCGCCGGGTACTGCGTGATGATCTGCTCGTTGCCCTCGACCGGGGAGTTCAGGGTGAGTCGGAGCCGCTGCTCCTTGTCCTCCACCTGGGCGGTCCGGACGTTGCCGTTGGCGATCTGCTCAAGCGCCTGCGACGTCGGCACCTCGTGGTAGCCACGGGTGTCGTCCGACAGGACGTTGTACCCCACGATCAACAGCAGGATCAGCAGGATCCAGATGAATGGGTTGCGGAGCAGGCGCTTACGGTCCATTCGGCTACGGCCGTCTTCCGGCCTCGACCCTCCCTGGCGTGCGTGTCGGGCGGAACTTGGGCGCCGCCCGGGCAATGGCTCCCCGTTCGGACCAGCGTACCGCCCACGGCGGCCTCCACCCCCGGAGTGGTACCACCCGGCCCGAGCGGCGGTCCGTACGTACAGGCACCGGCTGGCCGGCACCGCCGTGCTGTCCTCGCACGGCGCCTGACGTGGGGTCCAACGGAACGCCCCTCGGGAAAGTTCCCCCCTGGAGGGGAACCACCCCGCATCTCGCGGTGAGGCGGGTCACCTCACTCGGGGTGGTCGCCTACCGCCGAACGGGCCGTCCTGCCGGTCAGCTGGAGTACACCCTCGGCTCCAACGAACCGATGTAGGGCAGGTCGCGGTAACGCTCCGCGTAGTCGAGGCCGTAGCCGACCACGAACTCGTTGGGGATGTCGAAGCCCACGTAGCGCACCGGCAGGTCCACCTGCACGGCGTCGGGCTTGCGGAGCAGGGTGCAGACCTCGATGGACGCCGGGCCCCGCGTGCTCAGGTTCTTGAGCAGCCAGGACAGGGTGAGCCCCGAGTCGATGATGTCCTCGACGATGACCACGTCCCGGCCGGCGATGTCCCGGTCGAGGTCCTTGAGGATGCGCACCACTCCCGAGGAGGAGGTGGAGGAGCCGTAGGAGCTGACCGCCATGAACTCCAGCTGGGTGGGCACCGGCAGGGCCCTGGCCAGGTCGGTCATGAACATGACGGCGCCCTTGAGCACGCCGACGAGGAGCAGGTCGGTCGATCTCGACCCGGCCGGGTAGTCCTCGGCCAGCCGACCGGCCAGCTCGGTGACCTTGTCCTTGATCTGCTCTTCAGAGACGAGTACCGATGCGATGTCGCCGTCGTACACGGAGGGCATCCCCTTGGGAATCAGGTCCAGTCGTGGGTGGTCGCCAGGCCGCGTCGCCGAGGCTCACCCCGCCGGGCGACCGACCTGAAGCCTGCCATGCGCGCGCTCGACGACCAACCCTCCCGGTAGCCACACCCCGCCCTGCCCGCGCCAGCGCCCGACAAGATCATCTACAGCGCGCAGGTGCAGGTCAGTGAGCTCACGAGCCCCGTGGGAGATCAGCCACCCGCGCAGCACCCTGCGCCGCACCGCGACCGGCGCGCCCTCGACGGCCCGGACCTCCAGCGCACCGTGTCCTTGGTCACTCCCGGCTCGGGAGAGCACTTCGTCGGCCCACTGGTCAAGCGCGGCCCCGTCCTCCCTGAGCTGCGCGGACGTCCTGCACAGTGCCTCGGCGACACCCCCCTGGAGCACCTCCTCCAAGAGGGGGAGCACCTCACGGCGGAGCCGCACCCTGGTGAACCTCGGGTCGCTGTTGTGCGGGTCGGTCCAGGGTTCCAGTCCGAGCTCGCGGCACGCCCGCGCGGTCACGGCGCGGGAGCAGCCCAGCAACGGGCGCCCCCAGGGCGGGTCGAGGGCGCGCATACCCGAGATCGACCGGGGACCGGAGCCGCGCCCCAGCCCGAGGAGGACGGTTTCCGCCTGATCGTCGAGGGTGTGGCCGAGGAGGACGAGCTGGCGTGGATCACGCAGCGCCCCCCGCAGGGCCTGGTACCGGGCACGGCGGGCAGCGGCCTCGACCCCTCCTCCCCCGGCCACCTCCGGTCGGAGGACGAGGGTCTCGTCCACGCCGAGGCCGACCAGCTGTTCGGCCGCCCGTTCGGCCACCTCGCGCGAACCTGGCTGGAGGCCGTGGTCCACGACGACGCCCCGCACCAGCAGGCCGCGACGATGCCCCTCGTACACGGCCGCGGCCGCCAGGGCCAGGGAGTCGGCGCCACCCGAGCAGGCCACGTCGAGGCAGCCTGGTTCGAGGTGCCCCCCACTCGTCGCGGTGTCCAGCAGGGCCCGGACCGCGACCCGCGTGCGGGACACGGCGGGGGTTCGGTCACTCATCGTTCACGTCACGACGCCGTCGCCGCGTGGCCGTTCAGCCGTGCACGCGACGGAGCCAGGCCGCCGGCTCGGAGATCTCGGCGCGGGTCGGCAGGGTCTCCGGTGAGGTCCAGACCGCGTTGAACCCGTCCATGCCGGCCCGCCGGACGACGTGCCTGGTGAAGGCGGCTCCCTCGGCGTACTGGCGCACCTTGGCATCCACTCCCAGCAGGACCCGCAGGGCACGGTCGAGCAGTCCGCCGCCTCGCCGGCGCACCGTGAACCGCGCCCGGATGCGCCGCACGGAGGGCACCACCCTGGGTCCGACGGCGTCCATGACGTGGTCGGCGTGCCCTTCGAGGAGGGTGCCCAGGGCCAGCAGCCGGTCCAGGTGGGCGCGCTGGGCCGGTGACTGGAGCAGCTCGACGAGGGCGGGCGGCTCGCCGCCGTCGGACGACCGCCGGTTGCGGAGGGCCCGCACCAGCTCGGGTAGCCGGTCAAGCGCTCCGACGACGGTCTCGTCCATCGACCCGAGCAGGGTTCCCACCTCGGTGGCGAAGTGGTCGCGCAGCCACGGGACGGCGGTGAACTGCAGCCGGTGCGTCGCCTCGTGCAGGCACACCCACATCTGGAAGTCGGCCGGCGGCACCCGCAGCGCACGTTGGACCCCGACGATGTTGGGCGCGATGAGCAGGAGCCGCCCCTGCCCGTCGTCGCCGCCGAACGGGTCGTACTGGCCCAACACCCGCCCACCGAGGTAGGCGAGCACCGCTCCGGCCTGGACGCCGGCCGCCTTCGAGGCCAGCGCGGCGATCAATCCCGCGTTCCGCCGAGCGGGCATGGCCCGGTCGACCAGGGCCGCCATGCCCTCCACCGCGGAGGACGCCCACCCCGGGCGGTCGAGCACCAGCCCCTCCCGCAGGGGGAGGTCGTGCCCGAGCCCGGTGAGCTCCCTGACGTGGCCCTCCGCCTCCCCGCTCAGTTCGCGGAGCCCCGAAACGGCGCGGAGTGCGTCCTCCATCGGCACCTGCGGCCCTCGGCCGACGAGGCGTACCGCGGTGGACCTGGCGACGTCCCAGGCGATGGGGCCCGTCCGGTCGACCCGCGCGGGCACGGTTGCCACTGACTTGGCGTCCACACCCCAGACGCTACCGGAGGGCACCCCGGGCAGGTGACCGCGAGCGGTGCCGGGGCCCTCACCGACCGTGCGCCCTTTCCCGGCCCCGCCCGCCCCGTTCAGCGACAGCCGCAGGTGCGGATGGCCGCGGCCATCTCGTCGAGGGCGGCCCTCGCCTCCAGGGTGTTCGCCCCGTCTGACATCAGCGCGAAGACGAGGAGCTTGCCCTCGACGTCGGTGACGATGCCCGCCAACGTGCTCACCCCGGTCAGGGTGCCCGTCTTGGCCTGCACCCAGCCGCGGCCCTCCCGCGCGTTGTCGATGTACCTGCCACCCAGGGTTCCGCTGGCACCCGCGACGGGCAGGCCGGGCAACATCGGGCGCAGCATCATGGCGACCTCGTCCGGGCGGTCCGGCCCGACGGCCTCGGCGAGCAGCTCGGCCAGCACGGCCGGGGAGATGTCGTTCTCGGTGGACATCCCGCTCGCGTCGGAGAGGGCGACCGTGGAGACGTCGAGCCCGTGCTCGGCGAGGACCTCCAGGATGGCGGTGGTGGCTCCGGCGAAGCTCGGTTCGTGCCCGGTGGCGATGGCGAGTTCCCTGGCGAGGGTTTCGGCGAGGGTGTTGTCGGAGGTCAACACCATCGACTCGACCATCCGCTCGATGCTGGGTGAGGAGACCTCGCCGAGAACGGTCGCTCCCTCTCCCGCCACCGGCTCCCGACTGACCGCCACCGCGTCGGGAGGCACGCCCAGCCGCTCACCGAGCGCCCGCCCGACGGCGAGCGCCGGCTCCGAGGAACGCGGGGTGGTCGCGAGGAGGGGGTCCTGCCGGTCGACGTCGAGCATCACCGGCTCGACGGGCGCGATGTGCCCGCCCGGGACGTCCGACTCGCCCACGCCCGGGGCGAGCCGCTCACCGGTGTACCGGCTCGCGTCCACCACGATGCGTTCGACCGGCTCCGACGTGGCCGCCTGGACCTGCTCCACGAGGTCGTCCAGCCGGGCGGCGTCGGGGTAGTTGTAGGTCGGTGTGTCACGGGGGAGGACCGACAGCGTCGGATCGCCGCCGCCGACCAGCACCAGGGTCCCCGGCTCCTCCCCCTGGACGACCCGCGTCTCCAGAGTGGTGTCGTGCTCGACGGTGAGCAGGATCGCCGCCGCGGTGAGCAGCTTCGTGGTGGACGCCGGTGTGCGTGGGACGGCCTCGTCGAGAGCCCACAGGGTCTCACCGCTGGCGGGGTCGAGGACGACCCCGCTCAGGTTGCCCAACGCCGGGGATGCGCCGACCTGGTCGAGCCGCGCCGTCAGCCCCTCCGCGGAAGGGCCGCTCGCGCCCAGGTCGAGCGCGCGCAGCACCGGATCCGGCTCCACCGCCGGGGGGGCGGGTGGGCCGGGGGCCACCTCGGGCCCACGCAGACCGAGGAACCGTCCGACCGGCTCGACCGTGAACGCCGTCACCGTGCCGACCGCGACCACGAGGGCCAGGGCTCCGATGGCCAGCAGGCGGCCTCGCCCCTTCGGCGCCGGCCTCTCCTCCTCGTCCTCCGGGGGCTCCGTCGGCGGACCTCCCGGAGGGGGGCTCCCCCCGGACTCCTCCGCCCGCTCCACGCCCTCGGGGGCCGTGGCGACCGGGGCCTGGGGGGTATCCCCGGTCTCCTCGCTCGAGGACGAGGCCGCCGACGGGCCGGGGTCGGGCCGCATGAACGTGGTGCCGCCCCGGCCGGTGGCGGCGTCGCCGTCGGGCGCGGCGGTGGGCCGGCCGAGGGGGTCTGGTCCCCCGGGGGTGGGGAGGCCGTGGGCTGGCGTGGGCACCCGGGTGCGCACCGTCGGCAGCGCGTCCGGGTTGGCCGGGGTGGGCGGAGCCGTGGACGTGGGTGGCGGGCCCGGCCGGTGCGACGGCATCCCGGCGGGCGGGGTCCCCGGGTGCCTCGGGCGCCGCCGGCGGCCTGGCGGCGGTCCGGCCGGGCGCGCCCCCGACCCGCGCGCCCGAGGCCGCGGGCGGGCCGGCCGCCCAGCGGGCGTGGGGCCGGGTTCGGCCCGCGATCGGAGGGCGGGCGCGCGGGGGGCGGCGGCGTGGGGAGCGCGGCCGTCGGCCGGTCACCGGCAGGCGGACCGTCCAACGGCAGCGAGCCGGAGAGCGAGGTCGCGGCCGGCCCCGCGCCGGCGGCACCCGCCGGACGCGCGGGTGGCCCCCCTGGGCGCCCGCCAGGCCCGGGGTGCTGCTCCCCCGCCGCGTCGCGCTCGTTCACGGGCAGCACACCGCGCATGGGCGGTTGCCCCGGCTGGGGCTGCCCGCCGGGTGGAGTACGCGGTGGAGCGCCGGGGGGAGGCGGTTGCCCGGGGGGACCGGACTGTGAGGATGGCCACGGAACCTGGCCCTCCAACCGTGGTGAGGCCGACACAGGCTGCTGTTCCGCTGGGCCACGGGGTACGGTGCCGTCCGGAAAGCGGTCCCGTGAGCGGTCCTGCGCACCGTCGGTCCGGCCTGTCGGCCGGTCGTCCGGTGGCCTGGGCGCACCCACCGGTGGTTGTCCGGTTCCGGACACTCGGAGCTCCTTGGCAGTCATTCGGGCAACACGGGACTGGAGTGACATCCGCGACGGCGGCTCGGACGCGGCTTCGACGAAGTTCGCGCTCCAGACTAGGACGCGGGCACCAGCAGGACGCACGGTGCGGTCGGCGCGCCGCACCCACACAGAACAAGCGAGGATCCGAGTGGAGTTCGACGTCACGATCGAGATTCCCAAGGGGGAGCGGAACAAGTACGAGATGGACCACGAGACGGGTCGGATCCGTCTCGACCGGACCTTGTTCACCGCGACCCAGTACCCGGCCGACTACGGCTTCGTGGACAACACGCTGGGTGAGGACGGCGACCCGCTCGACGCGATGGTGCTGGTGCAGGAACCGACCTTCCCCGGCTGCCTGATCCGGTCCCGTGCCATCGGGATGTTCCGGATGCGGGACGAGAAGGGCGGCGACGACAAGGTCCTGTGCGTCCCCGCCGACGACCCCCGTTCCGAGCACCTGCGGGACATCCACCACCTCGCCGAGTTCTACAAGCTGGAGATCCAGCACTTCTTCACCGTCTACAAGGAGTTGGAGCCGGGGAAGAGCGTCGAGGGCGCCATGTGGGTCGGCCGGGCCGAGGCCGAGGCCGAGATCAAGCGGTCCTACGAGCGGCTGAGGACCTCGGACCACTGAGCGGGTCCGCGCCCACCGCCAGGTGGGGTTGAGGCAGGGTGGTCACCGGCCCGCCGGGCCCGCGCCACCCTGCCTCCGAACACGATCAGACCTGGCTGGTCGTCGAAGGTTCCGCCCCCCGAGCGGTTCCCTCCTCCGACCGAGCGCTCGGTTCCGGCGCACCCTCGGCCTGGGCCGCCGCGCGCTCCGCCGCGAGCTGCTCGAGGTTCGAACGGTCGGACAGGTGCACGTCCCGGAGGAACCAGGACAGGGCGAAGGCCAAGGCCACCACGCCGAGTCCGATCAGGAAGACCGTGCCGACCGCGCTCGCGAATCCCTCCAACACCGGCCGCGCCAACCTCGGGTCCAGCCCGTTCAGGAACGAGGTGTCGTTCAGGTCGAGGCCAGCGGACCCGCCGCCAGCTCCTTCCAGCGACGCCAGGAACCGCTCGTTCGCGGGGTCCGCCTGTACGGCGGGGTCGGTCAGGGCGCGCTGGAACTCGGGTGTCCGCGCGGCCGACTCGAAAGCGGACGTGATCCGGTCCCCCACGACGGAGAACAGGACGGAGAGGAACACCGCGACTCCGACGGTCCCCCCGTTCTGGCGGAAGAAGTTCGCCGAGGCCGTCGCCGCCCCGGAGTCTCTCGGCGGGGCGTCGTTCTGCACGTAGAGGGTCAGCGTCTGCATGCACTGGCCGAGCCCGCCGCCGAGGACGACCATGACCAGACCGATCTGCCAGAGCGGCGTGTCCACCGTCACCTGCGAGAACAACAGGTACGACAGGGTGAGCAGCCCGGTACCGAGGATCGGGAAGACCTTCAGCCGTCCGGTCCTGGCGATGAGTTGGCCGACGACCCCGGTCGCGACCATGATCCCGAAGGTGGTGGGCAACATCATGAGCCCGGCCTCGGTCGGGCTGAGCCCCTTCACGATCTGGAGGTAGAGCGGGACCGACATCATCCCGCCGAACATCCCGAGGCCGACCACGAAGTTGAGCACGTTGGCGAGCCGGAACGTCCCGGATCGGAAGAGCCGAGGGGGCAGCAGCGCCTCGTCCCCCATCCGCCGCTCCACCAGCACGAAGGCCACCAGCCCGACGGTGCCGACCGCGAACATCAGCAGCGACAGCGGTGAGCTCCAGCCCCACTCCCTGCCCTGTTCCGCCACCGTCAGCAGGGGGACGAGGCCCACGACGAGCGCGGCCGCTCCCCAGTAGTCCACGCGGTGCCGCACCGGGTGGTGCGGGATGTTGAGCACCTTGGCGACGATGAGGAAGGCGACCACGCCCACGGGCACGTTCACGAGGAAGACCCAGCGCCAGCCGGCCACCCCGGCCAGGTCGTCCAGATCGGCGAAGAATCCCCCGAGCACCGGCCCCAGCACGCTCGACACGCCGAAGACGGCCATGAAGTAGCCCTGGTACCGGCCCCGCTGCCGGGGGCTGACGATGTCCGCGACGATGGTGAGCGCCAGCGACATCAGCCCGCCGGCGCCGAGGCCCTGGACCGCGCGGAAGGCCGCGAGCTGGTAGATGGAGGCCGCGACGCCGCACAGGGCCGAGCCGACGACGAAGACCGTGATGGCCGTCAGGTACATCGGCTTCCGGCCGTAGATGTCGGACAGCTTGCCGTAGAGCGGCGTCGAGATCGTCGCGGTGATCAGGTAGGCGGTGGTCGCCCAGGCCTGCGCGGTCTGCCCGTGCAGTTCGTCGGCGATGACCCGCATCGCCGAGGAGACGATCGTCTGGTCGAGCGCGGAGAGGAACATGCCGGCGAGCAGGCCGCTGATGATGGTGAGTACCTGCCGATGGGTCAGTCCCCCGTCGGCGCGGGGACCGGTGTCCCGTGCCGCCATGCTGTTGCTCATTCACTTCCCCTGAGTGGACCGGCCCGCTCGTCGGCGAGCTCGGTGGTACGAGTTGGTAATCGTTCGGCACAGGCCGTGTTCGGCCTGGCGGGCTGGGGGGTCAGCGCCTCGCCGTCCGCCACGCCCCCGCCGTCGAGGACACGGCCGTGGAGTCGGCGTCGGGATCGGCACCGCTCCTGGAGCGGACCGTCGCCGTTCCCCCGGACGGCGAGCGGGCGCGCTCGGCGATCGGCCGGCCCCGGTGCACCGCGCGGCGGCCCCTCCCGCACGTGCGCGGCGACCCGTCGGCTCACCGTGGACGGCTCCGTCCGGAGCGCGGCGGCGAGCTCACCGGAACGGCGGGGGCGGGCGTGGAAGTGGGAAAACGGGGTGAGGCCCGCTGGCCCCGCCGCGACCGCGTCGGTCTCCTCGTCCGGTTCCCGCATCGCCAACCCCTGTTTGCCCGCATCACACAACTAGTTGCACGAAGCAAGCTTCCGCCGATCAGGGACGGCCGGCAACCGATTTGGCTATGAGCCGACTCTCAGCTGCTCCAGGTGACCGACCGGGCACCCCGCGCCATCGCGGTGCTCGCGGCCCCACCGCTTCGACGGCGCGGATCGCGCGTCGTGGGCAGGCGCGTCGTGGGCAGGCGCGTCGGCTGGCCCTGGCGCGTTTCCCGTCCCAAGGGCGCGGCATCAGCCCAGGGCACGTCCGGGCCGACCAGGCGCCCGGGTATCGGGGGCCGGGGGCCGGGGGCCGGGGGCGGACGATGGCTCAGCGGGGTGACCCGCGGCGAGCGGTGGCCGAGCCGCCATCACGACCGTCGACCGCCGCTCCGCCCTCCTGGCCCTGACTGGCGGCAGGTCCGGGCCGAGGGGGATCGGGATCAGGAGATGACCGAGCGAACCCAGTCCCGGTACACCGTCACCTCGGTGAACACGAGCCCGCCAACTCCGCAGACCGGGTCGCCGCCCCGGGAGTCGAGACCGGCCAGCCGCCAGGCCCCACCCTCCCTGACCACCGCCGGGCCGCCGGAGTCCCCGTAGCAGGAAGTGGCATCCCTGCTCACCCGCAGGCAGAGCTCGGTGGCGGCGTCCACTCCGGCGGCACGACAGCCGGCGGCCGCCGCCACGGGAACATCGAGCTGCCGCAGCAGCTCCGGGTACTCCCAGGAACACTCGAAGGTGCCGCAGGTCTTGCCCCAGCCCAGTATCCGAACCGTCGCTCCCTCGGGAGGTCGCCGCGCGGCGAGCGGCAGCGTCGGCGCCGGCACCGGCCGGGCCAACCGGAACAGCGCGATGTCCCCGGTGTGCCCGTTCCAGTGCGGATGGGTCACCATCTCGACGACCCGCTCGTAGCTGCCGCCCTCGGACCGGTGGTTCGTCCCGACCCTGGCCGTGTAGGCGGTGAGCTCGCCCTGGACGCAGTGCGCCGTGGTCAGCACCCACTCCGGGTCCACGAGCGCTCCGGCGCACCAGTGGTCCTTGCCCTCGGTCGGACGCTGGATCGAGACCACGAAGTGGTAGTCCTCGTCGCCCCCGACCCCTCCCACGATGCGCGCGGCGGGCTCCGCCGAGGTGGCCTCCTCGGCGGCGGCGACCTCCCTCCTCGGCTCGGCGGGCGAGACGGCGGTGGTGGACAGCGCGGCCACGACGGCCGCCAGGAAGAGTGCGCGCACGGGCCACGTCCTTCGGCGAGGGGCAACGGGGACGATCGTCGCCCGACACGCCCTCCATCGGCGCGCTCACGCGGCCCGTGTACCCCCTGAAGAGTGACTACCGGTCCACCGCTCGCCCCGGCTCCCGACCTCGGTCGGCACCGTCCTCGGCCGGGCCTCGAGGGCCGGCGCGCCTCCTCACCCGAGGGATCAGGCGGCCGACCTCCGTCCGAACTCCCGCTCCCCCTCCACCTCGACGTCCGACGCCCCTCCTCGCGGGGACACCGCACCCCGCCGGAAGGCGCGTAACTCCCAGCGCACCCGGTCCACGACGCGACGACGTCGTCGTGACCGGCGCACGTACCGCGCCAGCGGACAGACCAGCGTCAGCACCCACCAACTCACCATGATCCCGATCACAGTGCCACTCATCATGGACATGATCAGCACCTCCTCCGTTGGCCGAGAGCACGTGCCCCCGGAGGGATGACGTCCCAGCCGTGATCTTCACTCGAACGGATCAACACGGTCGTTCCGAGCCTCCGCTCCCACCGGGGTCACGTCACCAGGCACGGCGCGTGCCGGGACGCCGGGCCGCACCCCGGTGGTGGGCCGACGGGACGCCGACCGCTGACCGCCCCGAACGGCCGCGGGCGATGCACCCGGTCAGGGGATCTACCCGGAGCACACCTCCTGGTTGACTGGAGGCGCGGGCCGATCACCGAGCACGCCAACACTCCACGGAGGAGTCGGCATGACCTCAGGCGCGTCCGACCGGGTAGGGCACCTCCTGCGTTCGTTCGAGGAACGCGCACGGCAGGTCACGGAACTCGGCCAACGGTTGAGCGGGGTTCGAGGAGTCGCCACCAGTTCCAGTGGGGTGGTGACGGCGACCGTCACGCCCTCCGGAGCACTCGTCGACCTCCGGCTCTCCCCGGCCGCCACCGACCGGAGCCACGTGGCGCTGCGGCAGGAGATCCTGGAGACGGTGCGGGCGGCGACACGCGATGCCGCCGAGCGCCTGGAGGAGATGGTCGGTCCCGTGCTCGGCGAGGACGCCCAGCGCATCCGGGACGCGGTGTCCTCCGCCGGTGACTTCCCGGTCCCCCGTCCGGACGAGGACCCCCCGTCCGCACCCCGGGGTGACCCCGGCGGTGGTCCGTCCGACGAACCGCCCGAGACCTTCCTGCGGTAGGAGGCGACGTGACCGGGTTCGACGTCGATCCGGAGGCGCTGCTGGCCCACGGGGCCGGCAGTGAGCGACTCGCGGACAAGTTCGAGGAGCTGGGTGCGCTACTCGACCGCGCCAGGGTGGACGACCAGTGCTTCGGCCCGATCGGGGACGCGCTGCACCTCAGCGGCGGATACCACTCCGCGCTGGAGGAGTGCGAGGCGCTCGCCACCCAGGCCGCCGGTTTCCTGCGGACCGGGGCCGAGATGACCAGGGAGAGCGCCGCCACCTACCTCGGCGTCGACGACGGCCTGGCCCGCGCGCTGGAGTCGATCGGGGACACCCTGCGCGGAGGTGGGCGGTGACCGGCCCACCCAGCTTCGAGGAACTGAACGAGGACGCGGACCAGCGCGGCTGGTTCGACCAGGCCGCGGCCCGGGGCAGCTCCTGGTCCGGGGCCTACCAGGACCTCCAGGACGCGACCACACCGCCCGAGATCACCGCCGCGACCATCACGGGACGCCTGGAACTGTTGGAGGCAATCCGGTCACCGGGACAGGCCCTGGTCGGCAACGGGCTCGGCTTCCTGGTGTCCATCGTGCTCAGCCCCCTGGTGGAGATCGCCGAGTGGGCCATCGGCGACCCGGAGCAGATGCGGGCCACTGGGGAGGGCTGGGAACAGGTCGCCCGCTGGCTGGACGAGGTCTCGGAGGCCGAGGGTCGACGAGCCGAGGCCACGGAGGACTCGTGGCGGGGTGAGGCCGGAGACGCCTTCCGCTCGCGGTTCGCGGAATTCGCGGAGGGCGTCGCCGCCCTCGCCGCCGACATCCGCGACCTGCGGCAGGTCCTGGACCTGGTCGCCGACCTGTTCGACGCCTTCGTCGAGTTCACCATCCAGCTCATCACCGAACTGGTCATCGGGCTGATCGTCTCCTGGTTGGCCGCGCTCGCGGCGGCCTGGATCACCGCCGGAGCCTCGGTCGCCGCCGCGAACGTGACCACCACCATCCAGGTCGGGAGCACCGGGATCCGGCTCACCATGAGGGTCACCAGGCTGCAACAGCGGATCGGGCAGCTGGTGCGCAGGCTGGAGGCGCTGCTCACTCGACTGCGGGGCCCCTTCCGGGACCTCGTCAACCAGGCGGGGTCGCTGCGAAGCGGCAACGCCGCGCAGCGGTTCGCGATGCGGCGCGTCGACGGGAACCCGTTGGTCAACATCTTCACGAGGGCCGATGGGAGCACGCTCGCGTCCACCACGGGCAACCGGTTCTCCGCCGGCGTCGAGGGCACCCAGGCGCTGGCCACCAACATCAGCGAGGCCGTGTTGCGGAACGCGCTCGGCGGTCAGAGCAGGACCAGCGGAGCGGCGATGGCCGCGGCGGGTGACCAGCTCACCTCGGCCGCGATCGAGCAGGGCGCGGAACTCGCCCATGACGCGGCGACACCCGAACCCTCCGCTGAGGAACGACGAGCCGCCCAGGAACGGGGATTCCAGTGGTAGAGGTGCTCGCGGCACGGCACACCTGGTGCGCGCCGAGCGAACGGATCCGGCTCGCGACGCCCCTCGGGGCCCGGCTGCGGTTCGACGTCGCGGGCATGGACGAACACGGCGCGCCTCGGCGGGGTTGGCTCGCCAGGACGTCCGGCGCCGTCGGCGGCGCGGCGGGAGGCGCGCTCCTCGGGCTGGTGGACGCCCTCTCCGGCAACGACAACCTCAGCTCCGACCCTGGCCAGGTGCCCACCACCCTGGTCACCGGCCCGGGTCCGGAGTGCCTCGCGGTGTCCACCCTCAGTGGGGTGGACACACTCGCTCCGGGTGACCACTGGTTCCTCACCTCCACCCGGCTGGCCCTGCTCTCCTTCCTGCCCTCCGGCACCGAGGCGACCGGTTCCACGAGCGGAACACCCGCGGAGGCGGGCACCGGCCTGCTCGACCGGGCCCGACGCTTCGGCACCGGCATCCTCGGCAACGGGGACCCGGCAGCGCCACCCCTCCGGGGCAGTCTGCCTCTCGCCACCGCACGGGTGGAACTGCCGGCCAGTCGGGTCCGGTCGGTGGGGGTGGTGGCGAGGAAGCAGGGCGGCGGCAGCAGCGGCGTCCCCCCGCACTACCTGCGTGTCGTCCTCGACGACGGGTCCGCGTTCGAACTCGCCGCCCCCGGCCGGACCGAGGCGGCTGCCCGCCGAATGCTCGCCCTCGCGTCCTCCTGACCCGCACCCGACCCCGAACCAGAACGGAACCTCCTGGTGTCCCGCGAACTCACCGCACGAGCGCTGTCCCGAACCTGGACCCGGGCCGAACGGGGCGAACTGCTGCTCGCCGTGCTCGGTGGCCCCGGCGCCGGGCACCTGGGGTCGAGCCTCGGCGGCCGAACCCACCTGCCCCACCGCCCCACCGCGCCAAGCGCGCTCGCCACCAACACCGACATCGCGCGACCCGCGCTCACCGCCCCACTGGCGGCCGGCGGGTGGTCGGACGACGAGTGGGCCCACGACCCGGCGATGTGGGGGTGGATCACCGGGGTGGACCCCGGGGACCACGCGGTCCGGTTGGGCGACGCGCTGACCCACGCCGGCGCACGCTGTCGCCTCGCCCTGTCCAACCGCCGGCTCGCGGTGCTGGTGGAGGCGGGCGAGGTGGCGAGCGGCGAGCCGGCCCAGGCCTCACCCAGGGGGCACGAAGCCGGTTTCGCGGGCCGTCTCGGCGGCCTGCTGCGCCAGGTGCGGGGTGGGGCCGGTGAACGTGGCGTCGTCGCCCTGCACGAGGTGGACCGTCCGGAGCTCCGGTCGGTCTCGGCGGCGCCGCTCGGCCGCGCCGCGCTTCCCGAGTGGTTCCTGGGGTTCACCTTCGTGGACGGCTCCTCCCTGCTCGTCCGCCACGAGGACCCCGAGCAGCTGGTGGAGACCCTCCGCCTGAACCCGTGACCTGAGACCCGGACCCGGACCCGGCAGCGCATTCCGTGTCACGCGGCGTCGGTGGTGGCCAGCTGACGCCGTATCAGCGGGAGGAAGCGCGGAAATCCCTCACGACAAGGAGGAACCACCTCGTCAGGAAACGACGTACCCGAGGATGAACCGGCTCCGGGGCAACGCGATTCTCCGCAATCGTGATCCGCCCAGCGAACAGCACACCTACTGGACCAGGCCGCACGTCCCCGGCCCGCCTACGGCTCATCACACACCCATACCGCCCGGGACGGAATTCACCGAGCCACACCACCCCGACATTTCCCCTGCGGACAGGGAACAGGAGACCCCCTCGCTCCCGCTGCCCCGGCTGTCGGCCACGTGCCGCCGAGGACGAGTGCCCCGATCTGGTGAAGCTGGGCGACCAAGCCCCACGTCAGGGGCGTCGCTGGCACGATTGCTCCCAGGCCCCGGCCGTTCGCGCACGGCGGCTCGAGACCAGCGACGAGTACGGGTCAGGCGATGCGAGAGTACGAGTACGAGGACGAGGACGACTGCGCGGACGAGGATGACGACGAGGAATTCGCCCACATCAACCATTACTCGGGCGACGTGACCAACGTCGTGCGGGCGCGTGACATCCACGGGGATGTCAATTACTACGAGCGCGATCACGGAGTGTTCCACTACCGCATATTCCGGTACGCGGGAGCCACTCTGTTCCTCACCCTGTTCGTCACAGCGGCCGCCTACTCCCATCTGGTCAACGACATGCGGCTCACGTGGTGGGAGTGGGCACTGCTACCGGTTGTCACCGCGGGCCTGGTCCTAGTGATGTTCCACACCCACTCCTGGATATACCCCAATCCCAGCTTTCGTTCGTTCCGCGCATTTCTTGCCATCGCACTCATCGCACTTGGGTACAACTACGGTCCTCAGCTGGATGTCGTTGGGGATGTCTCGCCCGTACTCGCGCACTGGATCGTGCTGCGGTTCTGAGCGGTCACGCGTGAGGACCGAGGTGGCGGTGGTACCGATGCGTGCCGGTCGGGCGGCGTAGGGCTCGCCGCGAGCGCCGTCGGGAAGGCGTCGCCGCGATCAGCGGCCAAGCCCGTCGCAGCCGGACCCGTCCCATCGATCTCCTACCCGACGAGAGCCCCCGAACGCGACGAAGCCCAGGCCTCGTGAGACCTGGGCTTCGGGCTGAGCCGCCTGAGGGAATCGAACCCTCGACCTACGCATTACGAGTGCGTCGCTCTGGCCGACTGAGCTAAGGCGGCGCGCTGCGGGCACAGCACGAACAGTCTAGCGAACGGGGAGCGACCGGGACGAGCGGGGTCGGTATTCCGGCGACCTCGTGCCTGCCCACGGGAGGAGGCAGGCGGGTCCGCCCGCGCCCCGTCCGAGGCAGCGGGGCCAGTGCCCCGCACACCGGGAGCTCGGTCAGGTCAGCCGCGCCACAGCACCATGAGCATGGCCTCCACGGCGATGCGCGGTTTGACGTTCGCGGCGAGCGCGTCCCGGCACTCCAGTACCGACTCCAGCCGGCGCAGCGTCGACTCCGGCGTCCACCGCGCCGCCGCCGACCGGCTGTCCGCCTCCCGGTCCGGGTGGTTCAGCGGCACCGCCGCCCCGGCCGAGAGGACGAGTACGTCCCGGTAGAAGGCCGTGAGGTCGATCAACGCCTGGTCCAGCGAGTCACGCTGGGTGCGGGTGGTCCGGGACTTCTGCCGCTTCTCCAGCTCCCGGACGGCGGCGTTCGCTCCTCTGGTCGCCGCGGCGGTGCCCTTCCCCGTTCCGCCGGCGCCCATCGCCGTGCGCAGCGCCTCCTTCTCCTCCTCGTTCCGGATCTCGTTGGCTTCGACCGCGTCGGTCTCAGCGGCCTTGACCAGCTCGTCCGCGCACCGGAACACGTCGGCGGACCGGTGGAGCGCGGTGGGTATCGCCAGCACCGCCGCACGACGCTGCCTGGCGGCCTCGTCCGCCGCCAGGCGACGTGCCCGCTCCACGTGGCCCCCGCACACCGAAGCAGCCCAGTCGGCGAGTTCGGGGTCCACTCCGTCGTGGTCACGCAGTGCCCTGGCGATCTCCGCTGGGCGGGGGGTACCCAGCGCCAGCGGCCGGCATCGGGACCGGATGGTCACCGGGACGTCGTCGGGGTGGTCCGAGGGGGCGCACAGCAGGAACACCGTCCGCTCCGCTGGTTCCTCCACCGCCTTGAGCAGCGCGTTCGCCGCCCCCTCCGTCAACCTGTCCGCGTCCTCCACCAACACCACCTGCCAGCGGCCGGCGGTGGGTCGCCTGGCCGCCGTCTGCACGAGAGCGCGCATCTCGGCGACCGAGATCGACAACCCGTCCGGCGCGACGATCCGCAGGTCCGCGTGGGTCCCGGCGAGCGCGGTACGGCACCCCTGGCAGGCTCCGCACCCGGGTACCGGACCGGGGACGACGCACTGGAGCGCGGCGGCGAACACCCGCGCCACCGTCGTCTGCCCGGAGCCGGGGGGGCCGGTCAACAGCCAGGCGTGGGTCATGGCGCCCCCGCCAGTCCCTCCGCCGGAGACCGCCCCGGCCGCGGCGACCGCGGCGGCGTACAGCTCGGCCAGCACCGACCGCTGGCCCACGACCTCCGCCCAGACACCGGTGGTGGGAACCGCCGGCTGGCCGAGGACGGCTTCCACGCTCCCAGTCATCCCCACATTGTGCAGTCCCCCGCGAGGGGCCCCCGGAGCGGGCGAGCCCCTCGCGAACGGACCCGGCGGCTCAGGCCTCCGGCAGCGAGACCGTCCGCCCCTCGTACCCCTGGGAGTCGCTGATCATCCGGAAGCGGCGGTCCCGCAGCACGCGCCCCACCGACTCCCGGACACGCCGCTCGATCTCGTCCTCACTGCCGTCCGCGTCAACCACCAGGTAGCGGTCGGGATTGGCGGCCGCCATCTCTCCCAGCAGCCGCTTCACCTGCCAGTTGTGCTTGAGGTCCTCGGTGCCGGCCCCCCCGTCCGAACGGGGCTCCCGGTCGAGCAGCACCGTGATGTCCGCGTGGAGGCGCCCGGTCGCCCAGTCCCCCAGCCCCTCGAGTTCGCCTTGGGCCAGTCCCGCCGCCGCGCCGAAGTGGGCCAGCGGGCTGTCCACGTAGCGTTCCATCACCACGACGGCGCCCCCGTCGAGCGCGGGGCGGACCACCTGCTCCACCACGTCGCTGCGCACGGCCGCCGCGACCAGCGCGTTGGCCCGAGCACCCGAGACCTCGACTGACTTGAGCACGTTGCGCAGGCGCTGCTCGTCCAACGCCGGGTCAGCGGCGAGCACCACCCGGTTGCCGCCGGCGGTCAACCAGTCCGTGAGCCGCCGCGCCTGCTCGGCGGTGTCCACCGCCGTGTCCCCCTCGACGGCGATCAGGAGGCCGTTGCCCTCCCGCCTGGACCGGAAGACGGCTCGCAGGTCGGCGAGGATGGGCCGGCTGCGCCGGTCGTCCATCTGGCGGTAGGCGACCACCCCGAGCACGGCGGCCACGACTCCGGCCCCGAGCAGGATGGGCCGGGTGGCGTCGACCTCGACCTGGGCCCCGAAGAAGGACAGCGTCCGTGGCCGCAGGATCGCCAGCAGGGTCGGCACGAGCGCCAGGGCGCCCACGAGCACCACCCGCAGCAGCGACTGGACCATCGCGACGGTCCGTCCCCGGACCGCGTCGTCCACCTGGGTGCCGATGATGGTGAGACCGGTCAGGAAGGCCACACCGGCGAATCCCCCCACCAGTGGGACCACCAGGAGCGCGATCCACAGGTGCGGGGCCAGCGCCACCGGGAACAGGGCCAGGCCGGCCCCGACGATGGCCGAGCCGAAGAGCCGGTTGTGCGGGATGCGTTGCGCGAACTTGGGCGCACCCGCCATGCCACCGGCCAGCCCGAGGAAGATGGCGGCGAACAACAGGCCGTACCCGGTGTCACCGGCGGAGAGGCTGTTGGAGTAGAGCTGGGCGGTGGCGACCACGGCGCCCCCCGCGGCCACCGCACCGATGACACCGATGACCAGACCGCGGATCAACGGGGTGGTGCCGATGAAGCGGAACCCGTCCCGGAGCATCGACAGCGCTCCTGGCCGCTTCGCGGCCACGGCCTCGCCGCCGTCGCTCCCCTCGGAGGCGGGCTGGGGTGTCTCCCGTGCTTCCCCCGAGGCCTCATCACCGACCCTGCGCCGCAGGGACAGCTCCGGGATCCTGGTCGCCACGAGGATGGCGGACGTGAGGAAGAGCAGACCGTTGACGACCACCGCGATGTAGGCGATACCCAGTTCGCTCTCGAGCTGGAGGATCGGTCCGATCGCCGTGATCAGCGCGTACAACCCGGCACCGCTGATCACGGAGATGCCGTAGGTCATCACCAGGCTGAGCTGGTTGGCGGTCTCCACCTGGTCCCGCCGGCGCAGCAGGTTGGGGATCGCCGAGTCCTTCGCGGGTATCCACAGCAGCGCGCAGCAGCCGATGAGGAAGTTGGCGACGAACAGCCACAGCAGTGGGCCCGTCACGCTGTCCGACAGCGAACCGACCAGCGGGATGGAGAGGAAGAACAGGCATCGCAGGCTGTCGCAGACCACCATCACCTTGCGGCGGTCGAACCGGTCGGCGAGGATCCCCCCCACCGGGGCGAATAACAAGCCCGGCAGGAGTTGGGTCAGGACGACCGCGCTCAGGGCGAAGCTCTGGGCCAGGTAACTGTCGGTGAACTTGGCGACCAGTCCCGTCAGCGCCAGGAATGACAGCCAGTCACCCATGCTGCAGATCGCGCTGACCATCCACAACCGGCGGAACGCCGGGATGGCCAGAACGCTCCGTATCCGGTGGGCGGTCGTGGTGCCCGTTCCCCCGGTTTGCTGGCCAGTCGGAATGGCCGGCTGCGCCGCGCTAATGCTGACCACCCCCTGTTGGCCGTCGCTGCAAGGACCTGCGCTCAGAGTAGTCGGAAAATGTGATCAAGACGGCCGAACCGGCTGTCCGGGTGATGACAGCGATCACAGCACGTCCCCTCCGACCCCGGCTTCGCACGCTACGTCCCCGACGTTGAGGATTCGCTGAGGACACCGGTCCCTCGGTCAGGGGTCGGGGAGCACGGCAGGACGACGGAACGGACATCCCGCCTCCCCCGAAGGTCATGAGACCCAGTGGGCACCGATGATGACCGCGAGCATCAGCAGCGCCATGACCAGCGGAAGCAGTCGATGGGGAGTGGGGCCGGGCCGCTCCGCGATCACCTCGGGCATGGGGTAGGAGCCAGCCGCGCTCTCGGCCCACACCTCGGGGGAGACGGATTCCCGGTGAGGAGCTCGGGACTGGCTCGGGCGCGGGGCCGCCCCCCAGAGCCCGCCCTCCCGCTCGGCCGCGCGCCGCATCCGCTCACTCGGCTCGGGTGGGCGCACCGCGGCGACCGGCGCTGCCACCGCACCGGGTTCGCCAGGCCGAACCGCCGTCCACGCCGTCACCGGACCACCGGCGGCGTCGGTCCGCGGCGGTGGGGCGGGTGGGGCCTGGGTCCCGTCAGGCCCGGTCAACGCGTCCCCGAACATAGGCGCCACCTCCTGAGCACCCTCCTCAGGGTAGGGGTGCCCCGACGGCGGGCGCCCAACCGCCGCCCGGGGCCTTGCTCCGGTGCTCCCGCCTCGGCGGCCCGGTCAGGACTTGCTGGACGTCGCGCGCTTCCGGCCCCGCTTCGGGGTGGTGCCCTTCGCCCTCCGCTCCGCCAGCAGTTCGGCGGCTCGTTCGTCGGTCAGGGTCTCGACCGCGTCGGCCTTGCGCAGCGAGGCGTTGGTCTCACCGTCGGTCACGTAGGGGCCGAACCTGCCGTCCTTGACGACCATCGGCTTGCCGGAGGCGGGGTCGGAGCCCAGCTCACGCAGCGGCGGGGCGGCGGCGGCCGTGCGCCTCCCCCGCTTCTTGGGCTCCGCGTAGATGCGCAGGGCCTCCTCGAGGGTGATGTCGAAGAGCTGCGCCTCGGAGTCGAGCGAACGGGAGTCCGTTCCCCTCTTGAGGTACGGGCCGTACCTGCCGTTCTGCGCGGTGATGTCGGTGTCGGTCTCCGGATCCCGTCCGACGACGCGGGGCAGGGACAGCAGCCGCAGGGCGTCGGCGAGCGTGATCGTGTCCAGCGACATCGACTTGAACAACGATCCCGTCCTGGGCTTGCCCTTCTCGTCCTCACCGAGGACCTCGGTGACGTAGGGCCCGTAGCGGCCCTCCTTGGCGATGATCTCGCGCCCGGTGTCCGGATCGGTGCCCAGCGAACGCCCTTCCATCGGAGTGGCGAACAGCTTCTCGGCGATCTCGGGGTTCAACTCGTCCGGCGGCAGGTCCTCGGGCAGGTTGGCGCGCTGGGCGCCCTCCCCCCCGGCCGCGTCGGGCGCCGCCTCCCGCTCGAGGTAGGGGCCGTAACGGCCGACCCGTACGGTGACGGTCCTCCCGTCGGCGTCGGTGAACATGGGGATGGAGTTGATCTCCCTGGCGTCGATGTGCTCGACGCCGGAGCCGACCAACTTCTTCAGCCCGCCCGCTCGGCCCACCGATCCGCTCGGGCCGATGTCACCCCCGAAGTAGAAGTCCGACAACCACGCCGTGCGTTCCTGGCGGCCCGCGGCGATCCCGTCGAGCTCGTCCTCGAGGCCGGCGGTGAAGTCGTAGTCGACGAGGCGACCGAAGTGCCGTTCGAGCAGTCCCACGACGGCGAAGGCCACCCAGGACGGCACCAGGGCCGAGCCCCGGCGCCAGACGTACCCCCGGTCCTGGATGGTGCTGATGATGGAGGCGTAGGTGGAGGGGCGGCCGATCCCGAGCTCCTCCAGCGCCTTGACCAGGCTTGCCTCGGTGAACCGGGGCGGCGGGTTGGTGGAGTGACCCTCCGGGTCGAGGGAGGAGGCGGTGACCCGCTGGTCCTCGGTGAGCACCGGCAGTCGGCGCTCGGCGTCGTCCGCCTCGCCACCGGCCTCCGAATCCACCGACTCCACGTAGGCCTTGAGGAAACCGGCGAAGGTGATCGTCCGCCCGGACGCCGCGAACACGCACCGCTCGCCGTCACGCGCGGTCCCGCTGATCCGCACGCTCAGCGTCGTGCCCCTGGCGTCGGCCATCTGCGAGGCGATGGTCCGCTGCCAGATCAGCTCGTAGAGCCGGAACTCGTCGGTCTCCAACTCCCCCGCGACCTCGCCCGGAGTGCGGAACACCTCACCGGCGGGGCGGATCGCCTCGTGGGCCTCCTGCGCGTTCTTGACCTTCCGCGTGTACTGGCGGGGCTGGGGTGACAGGTACCGGTCGCCGTACAGCTCCGCCGCCTGGGAACGCGCCGCCGTGATGGCGGTGTCCGACAGGGTCGTCGAGTCGGTCCGCATGTAGGTGATGTAGCCGTTCTCGTACAGGCGCTGCGCGGTCCGCATGGTGCGCTCCGCCGAGAAGCGGAGTTTCCGCCCGGCCTCCTGTTGCAGGGTGGACGTCATGAAGGGCGCGTAGGGCCTGCGGGTGTAGGGCTTCTCCTCGACGCTGGACACCGTCAGTTCGGCGCCGTCGAGACCACGGGCGAGCTGGCGTGCCTCGTCCTCGGCCAGCACCCGCACCTCGCCGGAGCGGATGCGGCCGTCCGGCCCGAAGTCCCGGCCGGTGGCGAGCCTGTCCCCGTCGACGTTGACCAGCCGCGCCTGGAAGGTGCGGGGCTGTGCCTCGGGCCCGCCGTCGAGGACGGCGGCGATGTTCCAGTAGTCGGCCGAGACGAAGGCCATCCGCTCCCGCTCGCGTTCCACCACGATGCGGGTCGCCACCGATTGGACGCGGCCGGCGGACAGCTTGGGCATGACCTTCTTCCACAGCACGGGGCTGACCTCGTAGCCGTAGAGCCGGTCCAGGATGCGCCGGGTCTCCTGGGCGTCCACCAGGGAGTGGTCCAGATCCCTCGGGTTCGCCGCCGCCGCCCTGATGGCGGGCTCGGTGATCTCGTGGAACACCATGCGGCGCACCGGCACCTTCGGTTTCAGCGTCTCCAGCAGGTGCCAGGCGATGGCCTCGCCCTCGCGGTCGCCGTCCGTCGCCAGGTACAGCTCGTCGACGTCCTTGAGGGCGTCCTTCAACTCGCTGACGGTCGACTTCTTGTCGGGGGTGACGACGTAGAGCGGTTCGAAATCGTGTTCGACGTTCACGCCGAGGCGGGCCCACGGCTCGCTCTTGTACCTGGCCGGTACGTCGGCCGCTCCCCGGGGGAGGTCCCTGATGTGCCCCCGGGAGGACTCGACGACGAATCCACGCCCCAGGTACGAGGAGATCTTGCGTGCCTTGGCGGGCGACTCGACGATCACCAGCCGACGACCGCCGGAGCCCCCCGAACGGCTCCCGCCGCCCTTCTTCGCCCGTGTCGACCCTGCCACGCTCTCCTGCTCTCACTCGGTTCCCGGACTCGCCAGTGTGCACCGACAGCGACACTCCGCGCTGCCCAGGGTGACTCAGGAGCCACCTGGGCGCGCCCCCGCCCCACCCGTTCCAGGAGTGGAACGTCCAGCCTGGGCCGTTGTGTTCCGCGCCCCCGACCGCCGGGGCCGGCCGGCGCCCCTCATGGCTACTCAGAGTCATGCCGTTCCGCTGGCCGCGCCGCCTCGACCCCACATCGGGCGACGTTGGCCAGAGGCTGGTCCACCTCAGGAGGACGCCGGCCGGCGGAGGCGAGAAGCACGGGACCCGCGACCACGGCGGCGCACGGGGACGGCGGCGCCACGGCGGCCGCGAGCTCACGCTGGGCCGTCGCGCGGGTGACGGGGAGGACGTGAGCACACACGAAACCTCCGCCGCGAGGGCACCCGCCCGTGCCTTCCCCGCTCGTCCCCGATCCTAGAACACACGTTCTACTCCGAAGGGGCACAAGTAGATCACGAGCGGGTGCCGTGCCGGGCCGGGCGGAGTCGTGGCGGTGGGTCAGACCGACCGATCGCCGGTGGGGGTGCCGGCGACGATGCCGGCACCCCCGACCGCCCGGTGGGTCAGGCGGTCGTGTTGGCGGGGTCCCGTGTCTCCTCGGGAGCCTCCTCACCGATGGCGGTGGAGCGCCGCTTGGAGATCACGACGGCGACGACGATGATGGTCACCGAGGCCAGGGCGATCAGCGCCCGGGCCACCGGCGACGCGCCGTCCCCGACCGAGAGGGTGACCACCGCCGGGGCGATGAGCACCGCGACGAGGTTCATGACCTTCAGCAGCGGGTTGATGGCGGGTCCGGCGGTGTCCTTGAACGGGTCTCCGACGGTGTCCCCGATCACGGTCGCCGCGTGCGCGTCCGAGCCCTTGCCCCCGTGGTGCCCGTCCTCGACCAGCTTCTTCGCGTTGTCCCATGCGCCGCCCGAGTTGGCGAGGAAGACCGCCATCAACGTCCCGGCCCCGATGGCACCGGCCAGGTAGCCGGCGAGGGGGCCCACCCCGAGGCCGAATCCCACCGCGATCGGCGCGAACACGGCGAGCAGGCCAGGAGTGGCCAGCTCCCGCAGCGAGTCCTTGGTGCAGATGTCCACGACTCGGCCGTACTGGGGACGCACCGTCCCGTCCATGATCCCCGGGTTGTTCCGGAACTGGGAACGGACCTCCATGACCACGGCACCGGCCGCCCTGGAGACCGCGTTGACCGCGAGCCCGGAGAACATGAAGACGACGGCTGCCCCGATCACCAGGCCGACCAGCAGCCCGGGGTTGAAGACGAGGAAGCCGGAGAGGTCGAAGGTCACGACTCCGGCGATACCGGCCAAGGCCGTCTGGATCGCGTCCGTGTAGGAACCGAAGAGCGCGGTCGCCGCCAACACCGCGGTGGCGATCGCGATGCCCTTGGTGATCGCCTTCGTGGTGTTTCCGACCGCGTCCAGGTCGGTGAGGATGCGCGCGGCCTCCGGATCGCTGTCCCCCGCCATCTCGGCGATGCCCTGGGCGTTGTCGCTGACCGGGCCGAAGGTGTCCATCGCGACGATGACGCCCACGGTGGTGAGCAGCCCACATCCGGCGAGGGCCACCGCGAACAGCGCGACGGTGATCGAGCCGGAGAGCAGGAACGCCCCGTAGACGGCCGCGCCGATCACCAGCGCCGTGTACACGGCAGACTCGAAGCCGACGGAGATCCCCGAGAGGATGACGGTGGCCGCCCCCGTCCGCGAGCTGCGGCCGACGTCCCGCACCGGCCGGTGCTCGGTGCCGGTGAACCGCCCCGTGAGCCAGAGGATGACCCCAGCGAGGACGATGCCGATCAACACCGCCGCGGCGGCGATGAGCGCGGGGTTGCCCTCGGTCGTGTTCTCGCCGCCGGTCAGCTCCGCGAAGGTGCTGGGGAGGTAGACGAAGGCCGCGATGACGGAGAGCACCGCCGAGATCGCCGCCGAGAGGTAGAACGCCCGGTTGATCGCTCGGAGGCCGTTCTCACCCTGGCGCGCCTTCGTCGTGTACACGCCGACGACCGCGGTCAACACGCCGATCGCGGGCACGATGAGCGGGAACAGCAGGCCGTGCGTGCCGAATGCCGCGGTACCCAGGATCAGCGCCGCGACGAGGGTGACGGCGTAGGACTCGAACAGGTCGGCGGCCATGCCCGCGCAGTCACCGACGTTGTCGCCCACGTTGTCGGCGATGGTCGCCGCGTTGCGCGGGTCGTCCTCCGGGATGTTCTGCTCGACCTTGCCGACCAGGTCCGCGCCGACGTCGGCCGCCTTGGTGAAGATGCCGCCGCCGACCCTCATGAACATCGCGAGCAGGGCGGCCCCGAAACCGAAGCCTTCGAGGACCTTCGGTGCCTGTCCGGCGTAGACCATGACCACGACCGCCGCGCCGAGCAGCCCAAGGCCGATCGTGGTCATCCCGACCACCCCACCCGTGCGGAACGCGATCCTGGTCGCCTTCTCCCGACCGCCGGGCTCACCGGCGGCAGCCGCGACCCGGAGGTTGGCCCTGGTGGACAACCACATCCCGAGGTAGCCGATGGCCGCGGAGAACGCGGCACCGATCACGAAGAACAGGGACCGGCCGATCCTCTCGTTCGCATCCTCGGCGGGGAGCGCGAACAGGAGGAGGAACACCAGAGCGACGAACACGCCGAGTGTGCGGAACTGCCTGCTCAGGTAGGCCGTCGCCCCTTCCTGGACGGCGACGGCGATCTCCTGCATCTTGCTGCTGCCCTGCCCGGCGGCGAGTACCTCCCGAAGCAGGAAGTATCCGACGGCGAGAGCGGCCAGAGCGACGACGGCGACGACGGCGACGACGCCGTAATCACCCCCGGACAGCTCTAGGCCCTGCGCCCAGGTGCTCTGGGCGAGGTGGAGCCGGGACATTCCGTCCTCCTGATTGGTCGCTTTCTGTGTCCGGGCCTGTCACGAGAGTGGCGACCCGCGTCATGGGCGCGGATTGTATTGGCCATATTGGTGGCGTACCTCACGGTGTGTCGATCAACTCATCTTTTCTTCGGCCAAAGCTCGCCGAAATCGTTGATCGCCTGCTAGCGGAGGTGGACCGGCCAAGATCTGGTGGTCCGGTTGTGCGAGGCTCGCGGCATGGACCGGGGACACGCGAGGACCCTGCTTGACCAGGTACTGGGTGGCGTCACGGCGGGCGAGGACCCGCTGACGCACGTCGCCACGCTGCCGGCACGGGACGGGGAGCATGCCGACTGGCCGGCCTGGGTGCCCGGTGCCCTGGTGGAACGTCTGCGGGGGTTCGGTATCGACAGGCCGTGGGCGCACCAGGTGGCGGCGGCCGACCTCGCGCGGGCGGGCCAGGACGTGGTCATCGCCACCGGGACCGCCTCCGGGAAGTCACTGGCCTACCAGCTCCCGGTCCTGGCTGGTCTCTCCGACGACCCCAGGGCGACGGCGCTCTACCTGTCACCGACGAAAGCCCTTGGCGCGGACCAGCTCAGGGCCGCCCTCGAGTTGTCGGAGCGGGACGTGCGGCCAGCCGCCTACGACGGCGACACCCCCCAGGAGGACCGGGAGTGGGTGCGTTCGCATTCCCGGTGGGTGTTCACCAACCCCGACATGCTCCACCTCGGTGTCCTGCCTCGGCACCAGCGGTGGGCGCGGTTCTTCCGCCGGTTGTCGTTCGTCGTCCTCGACGAGTGCCACACCTACCGCGGCCTGTTCGGCTCGCACGTGGCGGTGATCCTGCGGCGCCTGTCCAGGATCGCGGCTCGATACGGGGCCTCCCCCGTCTTCGTCCTGGCCTCCGCGACGACCGCCGATCCCCAGGGGAGCGCCACCCTGCTCACCGGTCGGGAGTGCGTCGCCGTCGCCCGGGACACCGCGCCGCGCGGCGAACGCGTCGTCGCGTTGTGGGAGCCTCCGCTCTCCTCCGACGGGGAAGTGGAGGGAGCGGCGCCCAGCAGGAGGTCGGCCGGGGCCGAGGCCGCGCGGATCCTCACCGACCTCGTCGTCGCCGGTGCCAGGACGCTCGTGTTCGTCCGGTCGAGGGTGGGCGCCGAACTGGCCTCGCTGCACGCCCGGGACGCGCTGGGGCAGGTGGACGCGGGTCTGCCAGCGCGGGTGGCCTCGTACCGCGCCGGCTACCTACCGGAGGAGCGCAGGGAGCTGGAGCGGGCACTGACGTCCGGCGAGCTGCTGGGGCTCGCCACGACCAGCGCACTGGAACTCGGCATCGACATCGCCGGCCTGGACGCGGTGGTCGTCGCCGGCTACCCGGGGACCCGGGCGTCCTTCTGGCAACAGGCGGGGCGGGCGGGGCGGGCTGGGCAGAGCTCGCTGGTGGTCTTCGTGGCGCGGGACGACCCGATGGACACGTACCTGGTGCACCACCCCGAGGCACTACTGGGGGCACCGGTGGAGTCCACCGTGCTCGACCCGGCCAACCCCCACGTCCTGGCGCCCCAACTGGCCTGCGCGGCCGCGGAACTGCCGCTCACCCCGGGCTGCTTACCCGCCCTGGCCGGTGGGCAGGCCGAGGCGGTGCTGGCTGGACTGGTGGAGGCTGGAGTCGTGCGGCGCCGCCCGACCGGTTGGTACTGGACCCACCGGGACCGACCCCACGGCCAGGTGGACATCCGGGGGTCGGGCGGTGAGCAGGTCGTCGTCGTGGAGGGGGACACCGGTCGCCTGCTCGGGACGGTGGCTCCCGAGGCGGCGTGCTCGTCCGTGCACCCCGGTGCGGTGTACCTGCACCAGGGTGAGTCGTTCGTCGTCGACGAACTGGACCTCGCCGAACACCTCGCCCTGGTGCACCGGGAAACACCCGACTGGAGCACCTTCCCCCGCACGGTCACCGACGTCGTGGTGGTGGGGGAGGAAAGACGGCTGGAGTACCCGGGTGGTCTCACGGTCGGTTTCGGCGAGGTGGAGGTGATCTCCCAGGTCGTCGGATACCTGCGGCGGGCCCCGAGCGGGGCGGTGCTCGACCAGGTACCGCTGGACCTGCCGAGCCGGACCCTGCGGACGCGCGCGGTCTGGTACAGCCTCTCCGACGAGCTGGTGCGCGGAGTGGCGCCGGGGGGCGCCGGTCTCGACCCGGCGCGCGTCCCCGGCGCACTCCATGCGGCCGAACACGCGGCGATCGGCCTGCTACCGCTGTTCGCCACCTGTGACCGCTGGGACATCGGCGGCGTCTCCACCGTGGTCCACGAGCACACCGGGGAGGCAACGGTGTTCGTCCACGATGGACATCCGGGGGGAGCCGGATTCGCCGAGCGCGGTTTCTCCGCGCTGATGCCCTGGCTGGCGGCGACGCGGGAGGCCATCACCTCCTGCGAGTGTTCGGCGGGATGCCCGTCCTGCGTTCAGTCACCCAAGTGCGGGAACGGCAACGAACCGCTGGACAAGGCGGGGGCGGTGGTGGTGCTGGACCTGGTGCTGTCGTGCCTTCGGCGGTCGGGTACCCCTCTCGTGGCACCACTGGGGTCGGCGGACGAGGGCGGTTGAGCGCTGGTCGTGAGCGCGGCGCACCGTCAACGGCGCACGGTGAGCAGGCGCTCTCCCCGGGCACGCAGTTCCTGGGCCTCCGCGCGGACGGCGGCGGCGACGGCCTCCTCCACGAGGGTCACCGAGGGCAGCTTCCACCCGCACACCGAAGGCTTGACCCGCCAGTGCACGACACCGTGCTCGGCGGGGGTCGGCGGAAGGGTGATCCAACTTCCCCTGCCGTGCAGCACGACGCCAGGCTGGGCGAGGATTCGAGAGGGGGTCGTCGAGCCGGCGGCGACCAGGAAGAGCCAGGTGTTGTCCGGGGTGGCCACGATCGGGACGGGCTGGGCGTGCCGGCGGCGCAGCGTGCTGGCGATGCGGCGACCGAAGGGTGCGTCCACCTCCACGGCGTCGACGACGTAGCCGGTGGCCAGCAGGAGGCTGTAGGGACGCACGGACCACCAGGAAGCGGCCCTGTTCGCGTCCACCAGGAGGTGGTCGGCCCAGTCGGGTTCGACGGGGACCGGGCCGGAGTGCTCGGCCGCGGCGTCGCCGCCCACCCACTGGCCACCATCGAGGTAGCTGCCAGGGAAGACCGGCCACTTCCGCCAGGCGAGGCCGATCGCCTCGGCGCGGAGTTCGATGCGGAAGGCATCACGCCATCCTCCGGACCAGTCCATGGTTGTCCGCCTCTCCTGATGTCACCACTGCGGTTCTTCGTGGGTGAGATCTCGATCACCGCCCACAACCAGTCAACGGCAGCCGGGAGCCACTCGATAACCACTCGTCGACAGCCGGTAGGTACGGCACGCCGAGTGCACCCACCTGACCGGGCGACCGAAGGTTCCACTTCGCCCCGCGTTCCTCCCCGGAACACCGAATCGCGCCGAACCCGCCGCTCACCGCCGGTCAACAACCATTCGACGCGTGCGGGACAACCCAGCCCGCCGAGGATGCTGGCGCCTTCGTCCACCGCTGCCCCGGCAGGTCTCCCCGCCCTGGCGGCCGTTCCCAGGGCGGCTCGGCCCGGGCGGGAGATGCCGGTGGTCGGCCGAGGAGGGCCGACCGGCCACCGCTACCCGGTGCGGCCACGACCCGCCGCGGGCCGCTGGTGGTACCCGGTTCACCGGGCGACGAGGACACCGGACCTGGCGCGGGCGTGGACCGCACCCAGGAACTCGAACCCGGGGGCTTCGGCGCGCACCTCCACGCGGTAGTCCGCGATTCCCGGCTCGCAGGAGACCAGGACCGTGTCCATCCTCGTCGCGATCAGCTCCGCGCCCCCACAGGCGTTCGGGTCGCCCTCCAGCGCCCGGGTGGCCGCCGCGAGGGCCGCCAGCTCGGCGGCGGTGACGGCTCGCTGGCGGGTGAGTGAGACGACACCCAGGGCGACACCGAGTGCCAGGGCGATCACCAGTACCGCCAACAACACCGTGGACAGGATCGTGGCGAAACCTCCCTCCAAGCTGGGAGCGCCCGATCCAGGGCTCAGACCGGACAACGCTGGCTCACCTCCCCGCGAACCGATCCGTGGTCGCCCGTCCGGGATGCCGCTCGACGTGAGGTCCCGGGCGGGGAGCGTTCCCCGGCCGCCTTCGGTCCCGCTCGGAGGGCATGTGTGGCGACACCCCCGACTGCCCCCGCACGCCGCACGTCCGGCGGCACCGATCCAACACCGCGTGGTCGCGTGCCCAGGTGCGGGGAGGGAGATCCCCACCGATCCGCCCCCCGCCGGCCACGGCGGCCCGCTCCCGGTGAGTTCCGCACCCAGGCGGGGTGGAGCTCGTGCGGTTCCGAGCCAGCCCGCGACGACGCCGGGAAGTCCCTGCCGCTCCCGGCCGCACGTGGGGTGACGGGTGGTGTTGACGAGGGTGGGGCAGCCGTGTCGGGCGCCGACGCCTGTTCGGGGCGGGGTGCCGGGGGCGGGCCGGCCGGTCGGCCGGTCGGCACGTCGGGTTCCGCCACCGCATAGGCGCGAGCGGTGACCTTCACCGGTGGGACCAGCCCCCCGAGGGGGGCCGCTTCGACCAGGGCTTCGATCTCGTCACCCTGGACTCGTAGCGTCAGGCTCGCCCCGACCGGCGCGACCCGCCGGATCGCGACCTCCGCCCGGCCCTGCTCTCCCCGTGCGGCGAGCCTGGCGGCGATCCCGGCGGCGTCCTGGCAGCGCAGTTGGGCGACCATCACGGCGAGAGCGCCGATGGCGAGTGCGAGAACCACGGCCAGGGAGCAGGTGGCCAGTGCTGCCTCCACCGTGACGGCGCCCCGCTCAGCGCTGACGGCGACCTCCTCGCGCGGGGTGCGCGCGACAGGTCGTTCACGGGCCGCTGCCATCAGAAGCCCACGGAGAGGGCGCGTTGGACCAACGAGGCGAGTGCGGAGGCCACGGAGTCACCGGTGACCAGCGTGTACAGCACCGCCGCGAGCGCGGCGGCAGCCACTGTCCCGATCGCGTACTCGGCGGTGCTCATCCCCTCCTCGCCGGTCGTGGCGGACGCGGGGAGCACCTGGGCCGGTCCTCGTGAGGGGGACACCGAACGATGACGCCCGGGCGCCGCTCGTGTCCGGGACCGGGCCACCCACCTGGCGGCGTGCCACGACGGCCAGGACGGTCGCGGCTGGTCGGGTCGCCGAAGACGGCGGTAGAGACGGGCCAGGGGCGATGGCCCCTGGAACGACGGGCGGGACATCGGCTGCTCCTCAGGGAAGGGGGTGGGTGGAGGCGGTGTGGACGGTGGAGGGTGGTCGAGTCACCAGGTCGAGAGGACGTCGGCGGCCAGTCCGACGAGCACGGGCACGACTCCGAGCAGGAGGAATGCGGGAAGGAAGCACAGGGCGAGTGGCGCGGCCACCAGCACGCCCGCCCGTTGCGCGTCGGCCTCGGCGGTGTCGAGGGCGGCCGCTCGCGATTCGCGCGCCAGCCGTTCCGCTGTCTCCGCCAGCGCCGACCCAGCGCTCGCGCTGCGCCGCACGGCGGTGGCCAGCTCCCGCAGCTCCGGTTGGGCGCGGGCGGGTCTCCAGGCGGTCGCGGCGTCCTCCCCCCGCACGAGGAGGTCGGCGACCAACCGCAGGGGGCGGGCCACGACGCGGCAGTCCGAGTGGTCGAGCTCGTCGGACGCCAGCCGAACGGCGGCGGGTGGTGACATCCCCGAACGCAGGCAGGCCGCGAGCAGGTCCCAGGTGGCGGCGAGGGTCGCGGGGTCCGGCGGCCGGCTCCGCCGCCGGCCGGCGTGCCAACGGTCCACGAGGACGGTGAGCACCGCAGCGGCCACTCCGACCGGCAGGGCGGCTGGCCCCTCCGCGAGGAGGAACCCGACAACCGCCGCCGCCCCCGCTCGGACCGCCGGCCCGTTGGTCAGGATCTTCACCCGGCGCTCGTGGACTGGGCTGGTGGTCCGAAGGCGACGCCGTGCCACCCGCCAACCGAGTGGCGCGACCACGACCGCCACCGCCCAGACCATGATGGTGACGGCCGTCATCGGATCGTCCTGGTCGTCAGGTGGTGGATCCACCAGGAACCGGTGGTGACGAGCAACGACCCGGCGACGAGCAGGGCTCCGCCGGCGCTCGTACCCAGCAGGACCGCGACCGGCCCCGCCCCGACCGCCTCCCCCAGCCCGAGCGCGAGGAGGGGGAGTCCGGCCAGCAGTGTTCCCGTGGCCCGGGGGCCGGCCATCCTCGCCCGCACGTTGTCGGCGAACCGAAGCCGGTGCGCCACGTCGGAGCGCACGGCGTCCAGGACGAGTGCCAGCGGCAGCCCGTGGGTGGTCGCCAACGACCAGGCGCGACCGAGCCGGGCGGGGACGTCGGAGGAGAGCCCGGTGGCGACTGGCCGCGCCAGTTGGCGTTCGACGTCGCCTCCCAGGTGAACCGTGGCCGCCACCCGATCCAGCAGAGCCGACACCTCCGACCCGCTGTCGGCGGCGGCACGCCGCACCGCCGCTTCCGGGTGGGCGCCGGATCTGAGGTCGGCGACCAGCCGGCCCAGGCTGGCGCACCAATCCCTGGTCACGTCGAGCGTTCGGGCGATGCGACGAGACGCGCCTCGGCGCGCCCACCACCCCAGCAGCACCACGAAGCTGGAGACCCCGAGCGCCCAGCCGCCGACCAGACCCGCGATGGCGGGACCGAGGAGGACGATGGCTCCGGTCGCGTGGCGCGTTGCCCGTCCTCCCAGCCCGCGCTCGGGCCCCGCGGCGCCGCGCCTCAGCCGACGAACAGCGCCGCCCCCGGGCAGCGGAAGCAGGGCCGTGCCGATGGCCAGCGTGATCAGGCCGAACACGAAGCCCACCCCCCTCGGTGGCGCACCAGCTCCGCCAGGTCCTCCCACGCCGGCCCCCGCCCAGCTCCCCGCCGCCATGCTGGCGTGACCACGACCCGGTCGGTCTCCTTCGCCAGGACGCTGATCGAGTCGAGGACCCGGTCGCCGCCGGGTAGGCGGACCATGTGCAGCACGAGCCGGACAGCCGCTCCCAGCTGGCTGTGCAGAGCGGCCCGCCCCAGCCCTCCCAGGGCGGCCAGCGCCTCCACCCGGGCTGGCACCTCGGCGGGCGAGTTGGCGTGCAGGGTCCCGGCTCCGCCCTCGTGGCCGGTGTTCAGGGCGGCCAACAACTCGCACACCTCCTCACCGCGCACCTCGCCGACGACCAACCGGTCAGGTCGCATGCGCAGCGCCTGGCGGACGAGGTCGCGGGTGCTGATGCGACCGGCTCCCTCGACGTTGGGGGGACGGACGACGAGTCGTACGAAGTGCGGGTGGTCCGGGCGCAGTTCGTGCGCGTCCTCGACGCAGACGACGCGTTCCCCTGGCGGGACCGCACCGAGCATCGCCGCGAGCAGGGTGGTCTTCCCCGAACCGGTCCCGCCCACCACGAGGAAGGAGAGGCGGGCGAGCACCACCTGGCGCAGCAGCACCGCGATGCTCTCGTCGAACGTGCCGCTGGCCCGGAGTCCGGCCAAGGTGTGCGCGGCGGGCCGGAGAACCCGGAGCGACAGGCTGGTGGACCGCACGATGGGTGGCAGCACCGCGTGCAGGCGGACCTCGCCGTGCGACGTGGTCTCGGGAAGCCAGGCGTCGACGAAGGGAGACGCCTCGTCGAGACGCCTCCCGACCGCCGCCGCGAGCCGTTGGGCGAGCCGGCGGACCGCGTCCTCGGTATCGAAGGAAACGTCGGCTCTCACGAGGCCGCCGCCCCGGTCGACCCACACCTCGTCCGGGCTGGTGACCAGCACATCGGTCACAGTGGTGTCCCGAACGAGTTCGGCCAGCGGGCCCAGGCCCGCGAACTCCTGGTGCAGGACGCGGAGGGCGTGCAGGACGTCGGCATGTCCCACCACACCGGCCTCGGCGCGAACCGCGCGAGCGATGGCGGTGGGGGTCGTGGGCGACGCCGATTCGGCCAGTCTGCGGCGAGTGCGGGCGACGAGCGCTCCGGAGCGCACCCGCTCACCGGCGGTCGTGCTCGTCGAGGGATTCACGCCGCGCTCCCCTGCGCCGCCGACGGACCCGCCGCGCCGAGCACCCGTTCCGCCGCCGTGGCGAGAGGGCCGCGTGGACGGCCTCGGAAGGCTCCCCGGTCCAGGCGCCCCGCCAGACCTGGCTCCGGTCTCATCGTCGTCAGCACCGGGACTCCGACGGCTGTCGAGACGTCCCGTGCGGTGAGTCCTCCCGGAGCCGGGCCACGGACGACCAGTCGGGGTTCGCAACCGTGGTGGGTGAGCCGACGGACGAGCGCACCGGCCGCGGCGCAGGCCCGGACCTCCGCGGGAACGACGAGCACGCAGAGCGTGAGCCGCCACAGGCACGCCACGACGGCGGGAGGCAGCTCCCGGGGCAGGTCGAGGACCACGGGTTCTCCGGCTCGGTGCCCGGCGTCGAGGACGGCGAGCAGTGCTTCCGGGCTGGGCGGCTCGGTCGGCGCTCCTCCGGCGCTCGGACGGTCGCAGGACAGCACCGTGAGCCGTCCCGCCCCCTCGTCCACCGCGGGGAGAGCCGAGCGCAACGTGCTCGCGGTAAGCCGCCCGGTGGCGGTCGAGCAGCCCGACCACCGCAGGCCCGACACCTTCTCCATGCCCAGCGCCAGGTCGAAGCCCCCTCCGAGGGGATCGCAGTCGACCAGCAGCGGATGGCCGCCCCGCCTGGCCGAGGCCCAGGCCACCGAGGCGGCGAACGTGGATGCTCCCGCCCCGCCCCGGCCACCGAGGACACCGACGACGGGGGCGGCGCGGGTGGCGGGGGGCTCGGTGGCGTCGGCCAGCGCGGTGACCAGGAGTTCGTCGTCTCCGGGGAGTGTGACGACCCGGTCCACGCCCAGCAGCACCGCCGCGCGCCAGTTCCCTTCGGGCAGCGGACTGGTCGAAACCGCGAGAACTCCCCGTCTCCGCCCGAGGCCGGCCTCGGGCAACCGGGGCAGGGTGTCCGCGCCGACCAGCACCAGGGGTGCGGCCGCCCACCGCCGTCGCGCCTCGGCGATGTCCCACACCCGATCGACTTCGCACCCGGCCGCGGCCGCGACCCGCAGCACCTCGTCAGCGAGCTCGTCGTCCTCGACGAGCACCAGCGTTCGCGTCTCCACCGCGCACCTCCTGTCCGGACGGCTGCCGGGACGACGTCCCGAACTCGCGTCTCCACAGTGGCCCGGTCTCCGGATTCCGACGAGGGGCTGGACACCGCCCTGTGGACAACCGTCGGTTGTGGACAACTCGGCCGCCGAGCCGCGTCCCGGGCCGACCGAGGAGTACGTCTCCCCACCGGCCACTGCCAGGTGTCACGCCGGTGTCACGCTGCCGACCGCACGGCTCCGAGCCGGCTGGTGTCCGCGCCCCCCGGGGGGCGAGGGACCCCTTCCGCGCAGGGGTGGGGTGACGGGGAGTCCCCGGGCCAGCGGGGTCCCTCCCGCCGCGCGAACGGCGATGCGACGAGCCCCCGCGTCGGACGGAGCGGGGGTCGCCGCTTCCGGTGGGCGGCGCGGGGCACGTCCGCGCGGCGACCTCGGCGCTCCAGGCCCCGCTCGCGTCGGGCGGGGTCCCTCGGCTCGGCTCCGGGCGCGCCCCGAAGCCGCTCGCCGCACCGGGAAGCGGGAACACCGCGAGCTTGCCGGCGTCCAGGTCGCTGATCGGCACCGTTCCCCGAGGCGGGCGTCCGGACGGCCCACCGAGGAGGCGGGAGGAACGGGATGGCCTCGGCCGGCGCGGGTCAGGAGCGCGGAACCCACGGCGCGCGTGGAGGGGCCTGGGCGGGTCGCGTGCTGGCGGGTGACCGACCCCGGAGATGGGACGACCCCCGCCAGGGGGGAGGGACGGGGGTCGTCAGGGGTTCAGCCCCGGGGGGTCGAGCTGAACCCGTCCGGCGCTGCCGGACGTCTCTACTGTATCCCGCTCGGAGGCTCCGATGCGCCGAGTCCGCGCGAGCGCTCACCCACTATGACCTACCGGCACCTATGCTGTCGACGTGACGGCCACGAAGAGCGCCGAGCAGACGACGCGGCCCCCCAGGGTGGCCGCGTTCTTCGACCTCGACAAGACAGTCATCGCGAAGTCGAGCACCCTCGCGTTCAGCAGGCCCTTCTTCCAGGAAGGGCTCATCAACCGCCGCGCGGTGCTCAAGAGCGCGTACGCGCAGTTCGTCTTCATGCTCGCCGGGGCCGACGCGGACCAGACCGACCGGATGCGCGCGCACATCACCTCGCTCTGCGCCGGGTGGGATGTGGAACAGGTCCGGTCCATCGTGGAGGAGACCCTGCACGACATCGTCGATCCCCTGGTCTACAAGGAGGCGACCCAGCTCATCGCCGACCACCGCGAGCAGGGGCACGACGTGGTCGTGGTGTCGGCGTCCGGGGAGGAGGTGGTGGCCCCGATCGCGCGGATGATCGGCGCCGACCACAGCATCGGCACGCGAATGGTGGTCACGGAGGGCCGCTACACCGGGGAGATCGACTTCTACTGCTACGGGGAGAACAAGGCCGTCGCCGTGGCGGAGCTCGCGGAGACGCGCGGGTACGACCTCGGCTCGAGCCACGCCTACTCGGACTCGGTGACCGATCTCCCCCTGTTGGGCGCGGTCGGCCATCCCACCGTGGTCAACCCCGACCGCGCGCTGCGCAAGGAAGCCGCGCAGCGGGGGTGGCCGTCGTTGACCTTCGACCACCCGGTCTCGCTCCGCAACAAGATCCCCACCCCGTCCGGGACGGCCGTGGCGGCGGCGGCCGTGGGCCTCGGGGCGGTCGCGGCGGCCGGTGTCGCCTGGTTCGGGGTTCGCCGTCGTCGGAACCGCGGCTGAGACGAGGCCACCCCTAGCCGGCCTTTCCACTCGAACGGGCACCTTGCCGGGGGCGGTGAGTCGAGCTACAAAGGAGTTGAGGAGCCCGTACGGCCAGGGATGACGCGGAGGAGAAGCGTCATCCACCCCGGAAGGGCGCCTGGCTCGAACGGCGGGCACCCACGCTCAGCACGCCGCGGGAGGCTTTCGTCGGCAAGGGACTGCGTACGGGACGCCGGACGCCGAGTCCTGAAAGTACGACACAGTTGAACGCCTGGGGCCGCGCTCAGTTCCTGTCGGATGGCGCGCTCCCCTCCACCCGAGGGGAGCGCGCCATCGTCCGTCTCCACCGCCGCGCCCCCACCGCCGCCGTGGAACGGTCGCACGGGACCCTCGCCCACCCGTGCCTCCCTCTCGTCGAGCGCGCGGCGGGCTCGGACCGGCTCCCGCTCGGCCCTCCTCCTGCCCCCGCGCCGGGTGCGGCCACCACCTGAACGGGTCAGCTCGCCACCGCTCGTAGGGTCGCTCTCCTGGCCTTCCCGAGCGCCGCCGGCGGGGCCCCTGCCTGACGGCGGCACCCCCGCCCCCTCCTCGCTCCGGCACCACTCCATCGAGTAATAACCTGGCTCAAGATCCATCCGTTCGGGCCCGGGAGCACCAAAGCGCCACGCCCTGGCAACACGCTGCGTGGTGTGACGTTGACCCTCCATCACCAGGTGGGTAGCTTCCAGAGCGGGACCCCAGTCGGTCAGGCGTTGACGTGACGACTGGGCCGCCACCACCGTGAGCTCCGGCCCACCGCTGCTTCCAGGAGGTTTGATGGGCACGACACGCAGGTCCCGGCAGCTCCTCGCACTGGGGGTGGGAGCGGCCCTGCTGGCCGGGTGCGCCGGAGGCGGCACATCTGACGGTTCCGAGTCGGCGGCGCCGGGCGGCGGGGAGGCCGCCGACGCGATGACCGAGTGGATCGACGAGACCATCGCCGGCATGAGCCTGGAGGAGAAGGTCGGCCAGCTCTTCGTCACCTACGTCTACGGCACCAGCGCCGACACGGCCCACGACAGCAACCTGGAGGAGTTCGGCCTGGCCACCCCCGCGGAGATCATCCAGCGGTACCACCTGGGCGGCATCATCCACTTCTCCTGGACCGACTCGCTGGAGAGCCCTCGGCAGGTGGCCGAGCTGTCGAACGGAGTGCAGGACGCCGCGCTCTCCTCGGGAGCCGGTGTCCCGCTCACCATCTCCATCGACCAGGAGCAGGGCGCCGTCCTCCGGTTCGGCGCCCCGGCCACGGAGTTCCCCGGCAGCATGGCGTTGGGAGCGGGCCGCAGCGTGGAGGACGCCCGTGCGGCGGCCGCCATCACCGGACAGGAGCTGCGGGCGGTCGGCATCACCCAGAACTTCGCGCCCGTCGCGGACGTGAACGTCAATCCGGCGAACCCCGTGATCGGGGTGCGTTCCTTCTCCTCCGACCCGGAGCTCGCGGCCGACTTCGTCACCGCCCAGGTCGAGGGTTACCAGGACTCCGATGCGCCGGAACGAACCGTGTCGAGCTCGATCAAGCACTTCCCCGGGCACGGCGACACCAACGTGGACAGCCACCACGACCTCCCGGTCATCGAACACACCCGGGAGGAGTGGGAGGAGTTGGACGCTCCTCCGTTCCGAGCCGCGATCGAGGCGGGCGCGGACTCGGTGATGAGCGGCCACCTCATGGTGCCCGGTCTCGACGACTCGGGGATGCCGGCGACGCTCTCACCGACGATCCTCACCGGCATGCTCCGGGAGGAGCTGGGCTTCGACGGCCTGATCTACACCGACTCGCTGCAGATGGAGGGGGTCCGCTCGCAGTACCCGGATGACCGCATCCCGGTGCTCGCGTTGCTCGCGGGCGCCGACCAGCTGCTGATGCCGCAGCACCTGGACGTGGCGGTCCAGGGCGTGCTGGACGCCGTCGGGTCCGGCGAACTCACCGAGGAACGGATCGAGGAGAGCGTGCGGCGGGTGCTGCGCGCCAAGTGGGACCGGGGCATCGTCGCCGAGCCGCACGTGGACCCGGACCACGCCGAGGCGTTCGTGGGTTCCGAGGAACACCTCGCCACGGCGCGGGAGATCACCGACCGCACCGTGACGGTGCTCCGGAACGACGCCGACCTGCTGCCGCTCGACTCGGCACCGGGCAGCGTGCTGGTGGCCGGGTGGGACGAGGCGACGACCGCCGCGTTGGCGGAGGGCTTCGGCGAGCGCGGCGCGACCACGACGACGCTGCCCAACGACTTCCAACCCAGCCGGGAGCAGATCGGCCGGGCGACGGCGGCCGCCGGGGAGCACGACCTCACCGTGGTGCTCACCAACGGCGCGTGGCAGGACGCGCGCTCGGGGCAGCGGGACCTGGTGCGCGAGCTCGTTGCCACGGGGCAACCGGTGGTGGCGGTGGCCGTGCGGGACCCCTACGACGCCGCGTACGTGGAGGAGGCCGGGACCTGGGTGGCGACCCACTCCTTCAACCGGGTGACCATGGGATCGCTGGCCCGGGTGCTGCTGGGGGAGACGAGTCCTCGGGGTTCCCTGCCCGTCTCGGTGCCCGAGCCGGCCGGTTCCGGCGACCGGTTCCCCTTCGGCCACGGTTTGAGCTGGTGACCGGCGATGGCGGGACGAACGGGCGAGAGCGGGACGGCTGGCCGGTCCTCCCGGGGGCTGAGCAGGCGCGGCTTCCTGACGGCCACGGCCGTGACACCGGTCCTGGCGGCGGGTGCGGGTACCGCGCTTGGCTCGACGGTTGAGGAGGGCTCCGGCGCCGCCCTCGCACGCCAGGGCGGACCGGTGCGCACCGGAGCCGACCAGCTGGCGGCGCGGGCCTGGGCACCGCTGGCGGGACGTCGGTTGGGGGTGTTGAGCAACCCCACGGCGGTGCTCGCCGACCTGGAGCATGTCGTGGACTCGATGCACGCGGCCGAGGGAGTGGACGTTGTCGCCGCGTTCGGCCCGGAGCACGGGTTCCGGGGCACCTCGCAGGCGGGCGGTTCGGAGGGCGACTACGTCGACCCGAGGACCGGCATCCCCGTGTACGACGCCTACGGGGTCGACGCGGGGGCTCTGGCGGCGATGTACCGGAAGGCCGGGGTGGACACGGTGGTGTTCGACATCGCCGACGTGGGTGCCCGCTTCTACACCTACATCTGGTCGATGTACACCGCGATGCACGCCGCCGCGCTGGCCGGGGTCTCGTTCGTGGTACTCGACCGTCCGAACCCGATCGGTGGCCGGGCGGACGGACCCCAGCTCGACCCGGCGTTCGCCTCGGGGGTCGGCCGGAAGCCAGTGGTGTTGCGGCACGGCATGACGGCCGGGGAGCTGGCCGGCCTGTTCGACGCCGAGTTCCTTCCCGAGGACGCGGGCTCCGGAGTGCCCTCCCTTGAGGTGGTGCGCCTGGAGGGCTGGGACAGGGGGCAGGTGTTCGTCGACACCGGACTTCCGTGGGTCCCACCGAGCCCGAACATGCCCACTCCCGACACCGCGACCCTGTACCCGGGCACCTGCCTGTTCGAGGGGACGGTGCTCTCGGAGGGCCGGGGCACGACACGTCCGTTCGAGACGGTGGGCGCGCCGGGCCTGGACTGGCGGTGGGCGGGGTGGCTCAACGATCGGGGCTTGCCGGGCGTCCGGTTCCGGGAGACCTACTTCGTGCCCACCTTCGGCAAGCACGAGGGGGTCCAGTGCGGCGGCGTGACCGCGCACGTGACGGATCCGGCGGCCGTGGACCCGATCGAGGTCGGGGTGAGCATGCTGGTGTCGGCGCGCCAGCTCTACCCGGACGAGTGGGGCTGGCGTCCCGACCACTTCATCGACAAGCTGGCCGGGTCGGCCACGCTGCGCACGATGGTGGACGCGGGTGCCCCGGTCGAGGAGATCACCGGGTCCTGGGCCGCCGAGCTGGCCGAGTTCGAGGAGCGGCGGGCTCCCCACCTCACTTACCCGGGGAGGTGACCGTGCGCGCCACCCTGTCCACCCTGTGCGTGACGGCGGTGTTCCTGGCGAGTGGTCTTGGCTGGGGGGTCGGGGAGACGTCGGCGAGTTCCTCGTGGTCGGCGGAGTCGTGTCCGACGTTGCGCGAGGGGTCCCCGGAGGAGCTCGGCCTGGACTCCACGCCGCTCGTCGAGACGGCGGACCGGCTGCGGCGCTGGGCGGAACCCGCCACGGGCCGTCCCCTCTTCGCCGGGGCCGCGGTGTTGTACGCCCACCAGAACGTGGTGCTGCGGCGGGACTCCGCGGGGTACGCGCTCCGGTACGCGGACGGCGAGGGCCGTGAGCTGCCAGGCGAGGAGCAGCGCCCTGCCGGGACGGGCACGGTGTTCGACATCGCCTCGCTGTCGAAGCTCTTCACGTCGGTGCTCGTCATGCGGCAGGTGGAGGAGGGCGCCCTGCTGTTGGACGCCCCGGTGTCCCGGTACGTCCCCGAGTTCGGTGACAACGGCAAGGAGCGGGTGACCCTTCGCCAGCTGTTGACGCACACCTCCGGGCTCGAGCCGTTCCTGCCGCTGTGGCGGGACTGGCCGGATCGGGAGTCCCGGCTCCGGGCCGTCCTCGCGGTACGCCCGCAGGTGCCCCCGGGAAGCGCCTACGTCTACTCCGATCTGAACATGATCGCGTTGATGGTCGTGCTGGAGCGGGTGACGGGCCTGCCACTGGACGAACTGTTGCGGCGGGACGTCACCGAACCGCTCGGGCTGGCTGGCACCGGGTTCCGGAACGCGGACGACCCGGTGGGTGACGTCGCGGCCACCGAGTACCAGGTCGTGCCGGCCAGGGGGATGGTGCACGGCGAGGTGCACGACGAGAACGCCTGGTCGCTCGGCGGGGTCTCCGGCCACGCCGGGATGTTCTCCACCATCGACGACCTCGCGGTGTTCGGTCAGACGATGCTCAACGGCGGGTGCTACGGCGGGGCCAGGATCCTCCGGCCGAGCACGGTTCGCCAGATGCTCACCAACCACAACGACGCCTTCCCGAGCAACCCCCGGGGGCTGGGCTTCGAGTTGGACCAGCCCTTCTACATGGGAGGGCTGAGTGGTCCCCTCACCGCCGGGCACACCGGCTACACGGGTACCTCGTTGGTTCTCGACCCGCTCTCGAACTCGGTCGTCGTGTTGCTCACGAACCGGGTGCACCCCTCTCGGGACTGGGGCTCGATCAACCCAGCACGGGCGGCGGTGTCCGATGCGCTGGCCTCCGTGGTCGGCCGCGGCGACGGGAACTCTCCGTAGCCCTGTCGCCCCCGCCGGACCTCGGCCCGTGATCACGCTTCGTGGTCACGGGCCGATCGCGTTCGGCCGCCCCCGACGCGGCCCGTCCCATCCCGGCCCTTTTCCCACCACCATCCGTTGCGGTGAGCGCGCAACCACTAACGGGTGGCTTTGACACGTTTCGTAAACAAGCGGGCAACGGTGATAACGCGGGTGGCCCGTTCGGCGATAGGCCGTTCCGCAACGGCGTTTCTCGGGTTTTCGCGACGTTCCTGGTGGTGGAACGGCCTTCGAGGCGATCGAGATAACCGAGTGATGACGAGATGGATACGAGGATTGACCAATCAAAATGATTGTTAGTAAGTTTCCGACGTGACGAAGCGTATCGGGCAGAGCGCGGCGCAGACCGAGGGCAGCCCTCTTGTTCGGATCCGCTCACTGCTACCTGGCCTGGCCCGAGCGGAGCAGCGAGTAGCCAACGTCGTACTGGAGGACCCGGCGGCGGTCACGCACCGCAGCATCACCGAGGTGGCGGAGGCCGCCGGGACGAGCGAGACGACGGTGACCCGGTTCTGCAAGGCGATCGGCATCCGCGGCTACCCGGAACTGCGGCTCGCCCTCGCCGCGGACACCGCCCGGAACGCCGTCCGCGACGAGCAGAAGCTCGGCGGCGAGATCGGCCCCGGCGACGACCTGCACGACGTGATCGGCAAGGTCGCCTACGCCGACGCCCGGGCGGTCGAGGAAACCGCCGAACAGCTCGACCCCATCGCCCTCCGCAAGGTCGTGGACCGCGTCTCCGCCGCTCGCCGGGTGGACGTGTACGGCGTGGGGGCCAGCGCCTTCGTCGCGATGGACCTCCAGCAGAAACTGCACCGGATCGGGCGAGTCTCGTTCGCCTGGAACGACAAGCACATCGCGCTGACCTCGGCCGCGGTGCTCTCCGAGGACGATGTCGCGGTGGGCATCTCGCACACCGGCTCGACGGCCGACGTCATCGAGGCGCTGCGGGTGGCCAGGGCGAGGGGAGCCACCACGGTGGCCATCACCAACTTCCCCCGCGCGCCCATCACCGAGGTGGCGGACCATGTGCTCACCACCGCCGCCCGGGAGACCACCTTCCGCAGCGGCGCGATGGCGAGCCGAATCGCACAGCTCACGTTGATCGACTGCCTGTTCATCGGGGTCGCCCAGCAGCACTACGAAACGGCTCAGGAGGCGCTGGAGGTCACCTACGCCGCGGTCGTGGGACAGCGCCTGGGAAGTCGCCCGGATGGCAGGCGCAAGGCGAGGGACGGCATCTGATGAACATGCGGACGGGCCAGACGGTGGTACGCGTCAACTCCCCCACGGAGACGCGCAACCCGAGAACGACGGACATCGACCTGCTCCCCAGCGCCGACATCCTCAGGATGATCAACTCCGAGGACCGGCTGGTGCCCGACGCCGTCCGCGAGGTGCTCCCGCAGCTCGCGATCGCGGTGGACCTGGCGGTCCACGCGCTGCGTTCCGGCGGCCGGGTGCACTACGTGGGAGCGGGCACCTCCGGCCGGCTCGCGGTCCTCGACGCGGCCGAACTGATGCCCACCTACAACGTTCCACCGGACCTGTTCGTGGTCCACCAGGCCGGTGGTGAGGCCGCCTTCGCCCACGCCCTGGAGGGCGCGGAGGACGACGCCGACGCCGGTGCCTCCGCGATCGAACGGGCGGCGGGTGCCCGCGACTTCGTGCTCGGGCTCACCGCGTCCGGGCGGACCCCCTACGTGATCGGGGCGCTGACCGCCGCCCGGCGGTTGGGAGCCACGACGGCGCTGGTGAGCGCGAACCCCTCCAACCTGGAGACCTGCCGGCAGCAGGCCGACGTGGCACTGGCCGTGGACACCGGCCCCGAGGTCATCGCCGGTTCGACCAGGATGAAGGCGGGAAGCGCCCAGAAGCTGGTGCTGAACGCCTTTTCCACCGCGGTGATGGTCCGGCTCGGCCGCACCTACTCCAACCTGATGGTCAGCATGCAGGCGAGCAACGCGAAGCTGCGCGGACGGACGGTGACGATCCTTCGCGAGGCCACGGGTGCCGACGACGTCACCTGCGAACGGGCGTTGACCGAAGCCGAGGGCGAGGTCAAGACCGCGCTGGTGACCCTGCTCGCCGGCGTCGACGCCGACCGGGCGCGACAGGCACTCGACGAGGCGGACGGGCACGTCCGGGCCGCCCTGACCGAGCTGACGCACGCCTGAGGCGCCACGGGCCCGGCGGTGCCCGGCAGTCGGAGGAGACCGCCGGGCACCGGTCCGAACGACGCGGGCGTCAGTCGTCGGCGGGTTTGCCCAGACCCGAGGAGATCAACTCCATGACCGAGGAGTCCTGCAACGTCGTGACGTCACCGAGTTCGCGCTTCTCGGCGACGTCCCGCAGCAGGCGGCGCATGATCTTGCCCGACCTGGTCTTGGGAAGCTCGGGGACGACCATGATCTGCCGGGGTTTGGCGATGGGACCGATGACCGTCGCCACGTGCTGGCGCAGCTCGGCCACGAGCTCGTCGCCGCCCGCGTGTTCGGTGGCGTCCCCGCGGAGGATCACGAACGCGACGATCCCCTGGCCGGTCGCCGGGTCGCTGGCGCCGACGACCGCCGCCTCGGCCACGGCGGCGTGGGAGACCAGCGCCGACTCGACCTCGGTGGTGGAGATGCGGTGGCCGGAGACGTTCATGACGTCGTCCACCCTGCCGAGCAGCCACAACGCGCCGTCCTCGTCGTACTTCGCCCCGTCGCCCGCGAAGTAGTAGCCGCGATCGGCGAACCGCGACCAGTAGGTGTCCCGGAAGCGCTCGTCGTCACCCCAGATGCCGCGGAGCATCGCCGGCCACGGCTCGGTCAACACCAGGTACCCACCCCCGCCGGGGCCGACCGGCTCACCCGTCTCGTCGACGATCTCCGCCGAGATCCCGGGCAACGTCCGCATGGCGGAACCGGGCTTCGTCGCCGTCACCCCGGGCAGCGGGGAGATCATGATGGCGCCCGTCTCGGTCTGCCACCAGGTGTCCACGACCGGGGTCGCCCCGCCGCCGATGTGTTGGCGGTACCAGATCCACGCCTCCGGGTTGATCGGCTCACCGACGCTGCCCAGCAGGCGCAACGAGGACAGGTCGTAGTTGGCCGGGATGTCGCTGCCCCACTTCATGAACATCCGGATCGTCGTGGGAGCGGTGTACAGGATCGACACCCGGTAGCGCTGCACGATCTCCCACCAGCGGCCCTCGTGCGGGGTGTTGGGCGTGCCCTCGTACATGACGGAGGTGGCGCCGTTGGCGAGCGGACCGTAGACGATGTACGAGTGCCCGGTGACCCAGCCGATGTCGGCGGCGCACCAGTACACGTCGGTCTCGGGTTTGAGGTCGAAGACGGCGTGGTGGGTGTAGGCGGCCTGGGTCAGGTAGCCACCCGAGGTGTGCAGGATCCCCTTCGGCTTCCCCGTCGTGCCGGAGGTGTAGAGGATGAAGAGCGGGTGTTCCGAGTCGAAGTCCTCCGGGGTGTGCTCGGGGGACTGCCGGTCGACGGTCTCGTGCCACCAGAGGTCCCGGTCCGCCGTCCACTCCACGTCGGCGCCGGTCCGGTTGACCACGAGGACGTGGCGGACGCTGGGCGCGTCCCGCAGCGCCAGGTCGACGTTGGACTTCAGGGGTAGCGCCTTGCCGCGCCGGTACTGCCCGTCGCTGGTGATGACCAGCTTCGCCTCGGCGTCCTGGATGCGGGCGCGCAACGCCTCCGCCGAGAACCCGCCGAACACGACGCTGTGGGTGAGCCCGAGTCGCGCACAGGCCAGGAGGGCGACCACCGCCTCCGGGATCATCGGCAGGTACACGGCGACGCGGTCACCGGACCGCAGACCCAGTTCCGTCAGCGCGTTCGCCGCGCGCGACACCTCGGCGCGGAGGTCCGCGTAGGTGATGGTCCTCGTGTCACCGGGTTCGCCCTCCCAGTGGATGGCCACGCGGTCGCCGTGGCCGGCCTCCACGTGCCGGTCCACGCAGTTCACCGCGACGTTCAGCCGGCCCCCGACGAACCAGCGGGCGAAGGGCGCGTCCGACCAGTCCAACACCTCGTCCCACCGGGTCTCCCAGCGCAGGCGGTCGGCCTGGTCGGCCCAGAACGCCAGGCGGTCCCGGTCGGCCACCCGGTAGAGGTCCGGCGTGGCGTTGGCCTGGGACGCGAACCGCTCGCTCGGTGGGAACTCCCTGCTCTCGCGAAGCAGGTTGTCCAGGGTGACGGCGTCGTGCTCGGCCTCGGAGTGACCGGTGTCGTTGGTCATCGCGAAGGACCTCCCCTGCGTGGTCTACATCATCATGTGAGGGTGACCGTAGACGTCGGGCGGCCTTCTGGGTAGCAGCCCGAGGTCCGAGCCGGGGAGTCCGCGCGAGCTCCGCGGCGGCGCCAGGACGCCCCCACCTCCCCCGTCCGGGTGGCGACCCGGATGTCCGCCCGGACGGTGGTGGTCGCCAACCGGGGGCGGCGCCGGCTGGTGTCGCGGTGCCCACCGGTTGGGTACTGTCCGCCTCATGACCGACCCCCTCGCCCCGCTGCTCGGCCTTCCCGGCGTGGAGGAGGCCGTGCGGCGTGCTCGCGCCGACGTCGACGCGGTGCACCGCCACCCCGCGAACCGGCGCGGCTGGGCCACCACGGGCGCGGAGGCCTCCGTGCGGGCTGCCCGCGCCTCGGCGGGGATCGAGGGAGCCGCCGTCACGCTTCCCGACTCCGGTGCGGTCAGCGATCCGGTGCTGGCGGGCTCCCTCCGGCTGGCCGAGGCGCTGGGAGGCCTCCTCCCCACGTGGCAGCGGGCGCCAGGCCAGGTGCTGGCGCGGATGCACGTGCTCGCGGCCGCCGACCTCGTCGACGACGCTGGCCGCGCGGGACTTGGCCGGCCGCGCGCCGACGCTGGTGCCACGGACCGGCTGACGCTGCTCGCCGAGCTGGTGGCCGGTGGCACGCGGGCGCCAGCTCCGGTCCTGGTCGCGGTCGTGCACGGCGAGCTGCTGGCGCTGCGACCGTTCGGTTCGGCGGACGGCCTGGTGGCCAGGGCGGCGGCTCGGCTCACCGCCATCGCGACCGGCCTGGACCCGAAGGGCCTGGTCGTGCCCGAGGTGGCGTTCCTCCGCCGGCGCGACGACTACCGTTCGGCGGCCGAGGGGTTCGCCAGCGGCGACCCGGAGGCGGTCGGCCGGTGGATCCAGCACTGCTGTGCGGCGCTCACCACCGGGGCCACCGAGGCGAACGCGATCGCGGACGCGCTCGCGGGCTGACCCGGGTCAGCGGTCCGAGCGCGGGGGGCGCCGCCGCAGGAGCGCCCGCAGGTCCCCCCAGACGGTCTTGAGGGCCACGAAGACCAACAGCGCGGCGAAGAGCCGGTCGGACAGCCGTTGGTCCATCACCACCGACCACTGGCTGGCGGCGACGGTGGCCAACACCCCGGAGCAGCCGATCCACAACGACGCGCGCAGCGATCCGTTCCCCTTGCGCAGGGCGCGCGCCCCGCCCAGGATCGAGGTCGGGGTGATCACGAGCAGCGAGGTCCCCTTGGCCATCGCCGCGGGCGCGGCGAACCCCAGCTGCATCACCGGAACCATGATGGCCCCGCCCCCGATACCGGTCAGTGCCGAGAGCACGCCGATGGCCAGCCCGATCGGCAGCAGCCACAGCAGCGGCCACCCGGGCCCGACGTCCGAGGACACCTGGGGCGCCGGCCCGACCAACAGGTAGACGGCGGTGCAGATGGACACGACCGCGTAGGCCCACCTCAGCAGGGCGAGCGGCGCCCGGTTCAACAGCGAGGCGCCCAACCAGGCGCCGGTCATGCACCCGACCGCCAGCGGCACGGCCATCCACAGGTTGACCTGGCCGTGCCACGCGTAGGACGCGGCCCCGGCGACCGACAGCGGGGCCAGCGCGAGCAACGAGGTGGCCACGGCCTGCCGCTGGTCGAATCCGACCAGGGTGACCAGCAGCGGAACGATCGCCACGCCACCGCCGAGTCCGAACAGCCCCGACAGCGCGCCCGCGACCAGTCCGATGATCACCAGCTTCGCCCAGGGCACCCCGTCCAGCGTTCTCTCGTCAGCGGCGTTCTCAGACACCCGAGCAACATACGCCGGCCGCCCCGCTCTCCGGGGGCAACGATTACCTAGCTCACCTCGGCGGTTCCGCTTCGGCCGTCCGGCGGAGCGCCACCGGGCCCAGGTGGAGATCACCCGTGTCGCGCGTGCGGGTGTCCGGCGACATGGCACCATGACGCGGTGAGCAGCGCCGGACACCACAGCAACGGACGCTGGGACGGAGAGGGGACACCACCCATCCCCTCGATCCCGCTGTCCGAGGACGACCGCACCGACGGAGCCGCCGGGGAGAAGTCGATCGGCAACCTGGTCCGCCAGGCCACCGTTCACATGTCCACCCTGATCAGGGCCGAAGTCGAGCTGGCGAAACAGGAGATCACGGCCGAGGTCAAGAAGGGCCTGCGGGGCAGCGTCTACTTCGTGCTGGCCCTCACCGTCCTCGCCTTCAGCTCCTTCTTCCTGTTCTTCACGTTCGCCGAGCTGCTGGCGGTGTGGCTGCCCCGGTGGGCGGGTTTCGGAATCGTCTTCCTGCTGATGCTGTTGGTCGCCGGCTTCCTCGCCTACAAGGGATACCGCCGGGTCCGCAGCATCCGCAAGCCCGAACGAACCATCAGCACGGTGCGGGAGACAGCCGCTGGTTTCAGCGGCCACCGGGACCGCCTCGACGGCGGCGACCCGGACCGGACCGGCTGAGCAACCGCCACGGTGAGCCTGCCACCCGACCCGTCCACCGCCCGGCTCGCCGGCCCGTGGGCGCACCACGACGTCTCGGCCAACGGGATCCGCCTGCACGTCGCCGAGCTCGGTGAGGGGCCCCTGGTCCTCCTGCTGCACGGTTTCCCCGAGTTCTGGTGGGCCTGGCGAGGGCAACTCACCGCGCTCGCCGAGGCCGGTTACCGGGCGGTCGCCGTCGACCTGCGCGGCTACGGCGACTCCGACAAGCCCCCCAGGGGGTATGACGGCTGGACGCTGGCCGGTGACGTCGCCGGGTTGGTCAAGGCGCTGGGTGAGCAGCGAGCGCACCTGGTGGGGCACGCCTGGGGCGGCATGTTGGCGTGGACGCTCTCGGCCCTGCACCCGAGGCTGGTCAACTCGATCACGGTCCTCGGTGGCGCGCATCCCCTGGCGTTGCGGCGGGCGATCTGGCTCGGGCTGACCCGACCGTTGCGGCGAACCGCCCGCGCCCAGGCCCGGAGTGCGCGGCACCTCTTCGCCGCGCAACTGCCCCGCCTCCCCGAGACGCGGCTGACCAGGAACGCCGCGAGCCAGGTCGAGGCACTGCTGCGGGGGTGGTCGGGGCCGGACTGGCGGCAGACGTCGGACTTCGCGGAGGTGGCGCGCACGCACCGGACCGCGATGCTCATCCCCGGGGTGGCGCACTCGGCGATGGAGTACTACCGCTGGAGCGTGCGTTCCCAGTTCCGATCCGACGGGCGGCACTTCGCCGAGGCCGTCGACCGGCGGGCCACGGTTCCGGTCCTCCAGGTGCACGGGCGGCTCGACCCGTGTTTCCTCCCCGCGACGGCCGCCAGGTCCAGCCCCTGGACGGGGCCGAGATCGCAGCGCGTGGAACTGCCCGGCGTCGGCCACTTCCCCCACCACGAGTCCCCGGACCGGGTCAACGACCTGCTCGTCCGCTTCCTCACGCGGGTGACGGCCTGATCCGTCACGGGCGGGTTCGGTCCTGACCTCGCCGAGGGTGGCCGGGGCGGATCACCTAGGCGGAGCACTCACCTGTCGGGACCTCGTCGGTCAGACCGGTGGCCGTCCGGACGTCCTCGTCGATCTCGGCGTTGGTGAGCACGTACCCGGTCTCGCTCTGGTCGGCCGCGGCTCCGAACACGACGCCCAGGACCCGTCCGTCCGGGTCGACGAGCGGTCCTCCCGAGTTCCCGCTGCGCACGGCTGACCTGACCGTGTAGATCTCCCGTTCGACCGTGTTCTGGTCGTAGATGTCCGGGCCGGTCAGGGTCATCCGCTGCCGGATCCGGGCTGCGCTCGCCGTGTAGGGGCCGCCCAACGGGTAGCCGAGCACGATCCCCCCGTCGCCGGTCGCCGCGGGGTCCGGGGCGAAGTCGAGTGGTTCGGCGTACAGGTCGGGGACATCGAGCACCGCCACGTCCCGGCTCGGGTCGTACAGGACGACGGTGGCCCGCAGGCTCGCCCGCTCCACCTCCACCGTCACCTGGTCCGCGCCGGCGACCACGTGCGCGTTGGTCATCACGCGGTGCGGTGCGACCACGAACCCGCTGCCGTTGAGCAGGCGCTGGCAGCTCCTCGCCTGGCCGTGCACGCGAACCACGCTCTCCCTGACCCGTCGCACCGTGGCGCTCGCCTGGAGTTCCGGGTCGGGTGGGTCGACCTCCGCCGCCGGGGTTCGGGAGAACGGGTCGAGGACGTGCGGGAACCCGGAGAAGGCGAAGAGCCGTCCGAGTTCGTTGGGGAGCCCCTTCGCCTCGGGTGGCATCACGTCGTCGACGGTCCCGAGCACCCGGGACTCCTTGACCGCGGCCGCCAGCCAGGGCACGGACGCCGCCGAGGTGATCGGGAGGGCGACGAGCCAGGCCACCAGGACGACCATCAGGCCCTGGACGACGCCACCGAGGAAGTTGTCGACGCGGCTCAGCCGGGAGTGCCCCAACCTCCGCTTGATGCTCCTGCCCACGTACACGCCGGCGAGCTGCCCGATGACGACCAGGCTGAACAGGATGCTCAGGGCCACCGCGAGCTGGACGGACGGCCCCTCCAACTGGTCGGCGACCCAGGGCGCCAGCATGAGGCCCCCGACGGCGCCTCCGGCGACACCGAGGCCAGCGCAGATCGCCACCGCCATGCCGTGCCGGACCCCCGAGATGGCGCCGAGCACGACGGCGACCAGGACGGCCGCGTCGACCCAGTTCAC

Protein sequences of DBSCAN-SWA_1

>CP025990|2252700:2325731|2262103_2262589_-|AUS78554.1|DBSCAN-SWA
MFRTMLKSKIHRATVTQADLHYVGSVTIDEDLMEAADLLPGELVTIVDVTNGARLETYAIPGERGTGVLGINGAAAHLVHVGDIVILIAYGVMDEEEARTRPPRVLFVDGDNRVLRQDGDPAGVPEGYGLRSGAVVAGGSEDQPGETADAARSDAPLQTEG
>CP025990|2252700:2325731|2258882_2260346_-|AUS81604.1|tRNA|DBSCAN-SWA
MRVRREKRERMLASGIEPYPVSLPVTHGLGQVRAENPDLAPDTSTGRIVGVAGRVMFLRNTGKLCFATLRAGDGAELQAMVSLKQVGEEALSAWKADVDLGDHVFVSGEVITSRRGELSVLVDEWRMASKALRPLPVAHKDLAEETRVRQRYVDLIVRRQAAETVRTRSAVVRSLRESFHERGYLEVETPMLQTLHGGAAARPFLTHSNAFDIDLFLRIAPELYLKRCVVGGIERVFEINRNFRNEGSDSSHSPEFAMLEFYEAYGTYDTMAVLTRELVQEAATRVFGTQVVTLADGSEYDLSGEWASLTMYESLAEAVGEEVTPETPAERLRTLAASHGLDLAGGGAKLGHGKLVEELWEHLVGSALHEPTFVRDFPLETSPLTRQHRDKPGVAEKWDLYVRGFELATGYSELVDPVVERERLREQSRLAAAGDEEAMQLDEDFLRSLEYGMPPSGGTGMGIDRLLMALTGLGIRETILFPLVRPE
>CP025990|2252700:2325731|2304343_2304685_-|AUS78583.1|DBSCAN-SWA
MEGGFATILSTVLLAVLVIALALGVALGVVSLTRQRAVTAAELAALAAATRALEGDPNACGGAELIATRMDTVLVSCEPGIADYRVEVRAEAPGFEFLGAVHARARSGVLVAR
>CP025990|2252700:2325731|2283606_2284035_-|AUS78568.1|DBSCAN-SWA
MREPDEETDAVAAGPAGLTPFSHFHARPRRSGELAAALRTEPSTVSRRVAAHVREGPPRGAPGPADRRARPLAVRGNGDGPLQERCRSRRRLHGRVLDGGGVADGEALTPQPARPNTACAERLPTRTTELADERAGPLRGSE
>CP025990|2252700:2325731|2266042_2267083_+|AUS81606.1|DBSCAN-SWA
MLDWELAWSRALYGPNGFFARGERPDGHFRTSPLVGPAFAEAVVTLLDRVDHALGRPARVDFVDVGAGGGELAEEVRERAPSRLADRVVVTAVDVAPSPACRVPGVVWRSTPPRRVVGLVVANEWLDAVPCPVLVRRGGRWRRVGVDSAGREAVLDPVDAAVRAWLGRWWPIGRRARGGAELRAEAGTPRDRAWTSVVRGVRAGVAVAVDYHHRLADRLAGRVDAGTLAGYLRGRRVAPIPDGSRDLTAHVALDACAAAVHAGVGGPLRTTLTTQRRVLADLGVVRAAPSPSLAATDPFGWLDAAARSGGVAELTSPEGLGGFGWLVHEVALPVRVLASGDRSPVH
>CP025990|2252700:2325731|2306695_2307580_-|AUS78586.1|DBSCAN-SWA
MAAGSWAGAGVGGPGGAGAPPRGVGFVFGLITLAIGTALLPLPGGGAVRRLRRGAAGPERGLGGRATRHATGAIVLLGPAIAGLVGGWALGVSSFVVLLGWWARRGASRRIARTLDVTRDWCASLGRLVADLRSGAHPEAAVRRAAADSGSEVSALLDRVAATVHLGGDVERQLARPVATGLSSDVPARLGRAWSLATTHGLPLALVLDAVRSDVAHRLRFADNVRARMAGPRATGTLLAGLPLLALGLGEAVGAGPVAVLLGTSAGGALLVAGSLLVTTGSWWIHHLTTRTIR
>CP025990|2252700:2325731|2323534_2324491_+|AUS78596.1|DBSCAN-SWA
MSLPPDPSTARLAGPWAHHDVSANGIRLHVAELGEGPLVLLLHGFPEFWWAWRGQLTALAEAGYRAVAVDLRGYGDSDKPPRGYDGWTLAGDVAGLVKALGEQRAHLVGHAWGGMLAWTLSALHPRLVNSITVLGGAHPLALRRAIWLGLTRPLRRTARAQARSARHLFAAQLPRLPETRLTRNAASQVEALLRGWSGPDWRQTSDFAEVARTHRTAMLIPGVAHSAMEYYRWSVRSQFRSDGRHFAEAVDRRATVPVLQVHGRLDPCFLPATAARSSPWTGPRSQRVELPGVGHFPHHESPDRVNDLLVRFLTRVTA
>CP025990|2252700:2325731|2255818_2256703_+|AUS81603.1|DBSCAN-SWA
MSMLTRVRAGHRSAPPAPEPGTTIAHSIEATRAPSWMALRFGAPPEEGETWVGCARALADPGFFPSWQARLGDWLRERFGESPDRTTSGYLMSWYLHAPGFLAGMLFHTARRVPHLRPADLAFRLADSRPHVDGVALLSEGFACLPDDPAAGTARATVVADERALAALLRARFVDHAARFVTAFAPHTRLGRRTLWAAATDVLDTALWNAGRLGGDEGAGVGDASLVLGCSDTDPLTSGSTLYSVTGEDNGQHWTRRRQSCCFHYALPGVERACVTCPRVSDAERADRVRRGGD
>CP025990|2252700:2325731|2292090_2294118_-|AUS78578.1|DBSCAN-SWA
MVSAICSMGDWLSFLALTGLVAKFTDSYLAQSFALSAVVLTQLLPGLLFAPVGGILADRFDRRKVMVVCDSLRCLFFLSIPLVGSLSDSVTGPLLWLFVANFLIGCCALLWIPAKDSAIPNLLRRRDQVETANQLSLVMTYGISVISGAGLYALITAIGPILQLESELGIAYIAVVVNGLLFLTSAILVATRIPELSLRRRVGDEASGEARETPQPASEGSDGGEAVAAKRPGALSMLRDGFRFIGTTPLIRGLVIGVIGAVAAGGAVVATAQLYSNSLSAGDTGYGLLFAAIFLGLAGGMAGAPKFAQRIPHNRLFGSAIVGAGLALFPVALAPHLWIALLVVPLVGGFAGVAFLTGLTIIGTQVDDAVRGRTVAMVQSLLRVVLVGALALVPTLLAILRPRTLSFFGAQVEVDATRPILLGAGVVAAVLGVVAYRQMDDRRSRPILADLRAVFRSRREGNGLLIAVEGDTAVDTAEQARRLTDWLTAGGNRVVLAADPALDEQRLRNVLKSVEVSGARANALVAAAVRSDVVEQVVRPALDGGAVVVMERYVDSPLAHFGAAAGLAQGELEGLGDWATGRLHADITVLLDREPRSDGGAGTEDLKHNWQVKRLLGEMAAANPDRYLVVDADGSEDEIERRVRESVGRVLRDRRFRMISDSQGYEGRTVSLPEA
>CP025990|2252700:2325731|2267263_2268412_+|AUS78558.1|DBSCAN-SWA
MTVGVGAGAAHLGVDRVVDLGPLHPAAHGAYRLRLAVSGPADDPVITSATPLVGHLHRGAEKLFEVRDYRQILALANRHDWLAAFCNEMAVAMAVERMLGMTVPDRASWLRTAFCELNHALALVVFLAPVAEAGGRGPRHVAARDGLVRARESVQRVLEEAAGGRIHFMANRVGGLREDVPAGWRDGVRAALDVVARGLDAARSVTVSDGDFRHRHRGLGVLTTGAALRLGVTGPAGRAAGVDLDLRRDDPGPAHAELGVTPRLGTRGDALDRVECMLDDADQALRLVRSCLDRLPPGPVNLRLPKAVKPPEGSVYVWTEAPLGVTGVHLVSRGDRTPWRLKLRTPSFNNVQALSPLLVGCRVADLPTVLASFAVVVGDIDR
>CP025990|2252700:2325731|2318033_2318960_+|AUS81613.1|DBSCAN-SWA
MRTGQTVVRVNSPTETRNPRTTDIDLLPSADILRMINSEDRLVPDAVREVLPQLAIAVDLAVHALRSGGRVHYVGAGTSGRLAVLDAAELMPTYNVPPDLFVVHQAGGEAAFAHALEGAEDDADAGASAIERAAGARDFVLGLTASGRTPYVIGALTAARRLGATTALVSANPSNLETCRQQADVALAVDTGPEVIAGSTRMKAGSAQKLVLNAFSTAVMVRLGRTYSNLMVSMQASNAKLRGRTVTILREATGADDVTCERALTEAEGEVKTALVTLLAGVDADRARQALDEADGHVRAALTELTHA
>CP025990|2252700:2325731|2288667_2289345_+|AUS78575.1|DBSCAN-SWA
MSRELTARALSRTWTRAERGELLLAVLGGPGAGHLGSSLGGRTHLPHRPTAPSALATNTDIARPALTAPLAAGGWSDDEWAHDPAMWGWITGVDPGDHAVRLGDALTHAGARCRLALSNRRLAVLVEAGEVASGEPAQASPRGHEAGFAGRLGGLLRQVRGGAGERGVVALHEVDRPELRSVSAAPLGRAALPEWFLGFTFVDGSSLLVRHEDPEQLVETLRLNP
>CP025990|2252700:2325731|2314126_2315467_+|AUS78590.1|DBSCAN-SWA
MAGRTGESGTAGRSSRGLSRRGFLTATAVTPVLAAGAGTALGSTVEEGSGAALARQGGPVRTGADQLAARAWAPLAGRRLGVLSNPTAVLADLEHVVDSMHAAEGVDVVAAFGPEHGFRGTSQAGGSEGDYVDPRTGIPVYDAYGVDAGALAAMYRKAGVDTVVFDIADVGARFYTYIWSMYTAMHAAALAGVSFVVLDRPNPIGGRADGPQLDPAFASGVGRKPVVLRHGMTAGELAGLFDAEFLPEDAGSGVPSLEVVRLEGWDRGQVFVDTGLPWVPPSPNMPTPDTATLYPGTCLFEGTVLSEGRGTTRPFETVGAPGLDWRWAGWLNDRGLPGVRFRETYFVPTFGKHEGVQCGGVTAHVTDPAAVDPIEVGVSMLVSARQLYPDEWGWRPDHFIDKLAGSATLRTMVDAGAPVEEITGSWAAELAEFEERRAPHLTYPGR
>CP025990|2252700:2325731|2308694_2309795_-|AUS78588.1|DBSCAN-SWA
METRTLVLVEDDELADEVLRVAAAAGCEVDRVWDIAEARRRWAAAPLVLVGADTLPRLPEAGLGRRRGVLAVSTSPLPEGNWRAAVLLGVDRVVTLPGDDELLVTALADATEPPATRAAPVVGVLGGRGGAGASTFAASVAWASARRGGHPLLVDCDPLGGGFDLALGMEKVSGLRWSGCSTATGRLTASTLRSALPAVDEGAGRLTVLSCDRPSAGGAPTEPPSPEALLAVLDAGHRAGEPVVLDLPRELPPAVVACLWRLTLCVLVVPAEVRACAAAGALVRRLTHHGCEPRLVVRGPAPGGLTARDVSTAVGVPVLTTMRPEPGLAGRLDRGAFRGRPRGPLATAAERVLGAAGPSAAQGSAA
>CP025990|2252700:2325731|2275851_2276406_-|AUS81608.1|DBSCAN-SWA
MYDGDIASVLVSEEQIKDKVTELAGRLAEDYPAGSRSTDLLLVGVLKGAVMFMTDLARALPVPTQLEFMAVSSYGSSTSSSGVVRILKDLDRDIAGRDVVIVEDIIDSGLTLSWLLKNLSTRGPASIEVCTLLRKPDAVQVDLPVRYVGFDIPNEFVVGYGLDYAERYRDLPYIGSLEPRVYSS
>CP025990|2252700:2325731|2300865_2303238_+|AUS81610.1|DBSCAN-SWA
MDRGHARTLLDQVLGGVTAGEDPLTHVATLPARDGEHADWPAWVPGALVERLRGFGIDRPWAHQVAAADLARAGQDVVIATGTASGKSLAYQLPVLAGLSDDPRATALYLSPTKALGADQLRAALELSERDVRPAAYDGDTPQEDREWVRSHSRWVFTNPDMLHLGVLPRHQRWARFFRRLSFVVLDECHTYRGLFGSHVAVILRRLSRIAARYGASPVFVLASATTADPQGSATLLTGRECVAVARDTAPRGERVVALWEPPLSSDGEVEGAAPSRRSAGAEAARILTDLVVAGARTLVFVRSRVGAELASLHARDALGQVDAGLPARVASYRAGYLPEERRELERALTSGELLGLATTSALELGIDIAGLDAVVVAGYPGTRASFWQQAGRAGRAGQSSLVVFVARDDPMDTYLVHHPEALLGAPVESTVLDPANPHVLAPQLACAAAELPLTPGCLPALAGGQAEAVLAGLVEAGVVRRRPTGWYWTHRDRPHGQVDIRGSGGEQVVVVEGDTGRLLGTVAPEAACSSVHPGAVYLHQGESFVVDELDLAEHLALVHRETPDWSTFPRTVTDVVVVGEERRLEYPGGLTVGFGEVEVISQVVGYLRRAPSGAVLDQVPLDLPSRTLRTRAVWYSLSDELVRGVAPGGAGLDPARVPGALHAAEHAAIGLLPLFATCDRWDIGGVSTVVHEHTGEATVFVHDGHPGGAGFAERGFSALMPWLAATREAITSCECSAGCPSCVQSPKCGNGNEPLDKAGAVVVLDLVLSCLRRSGTPLVAPLGSADEGG
>CP025990|2252700:2325731|2276469_2277462_-|AUS78565.1|tRNA|DBSCAN-SWA
MSDRTPAVSRTRVAVRALLDTATSGGHLEPGCLDVACSGGADSLALAAAAVYEGHRRGLLVRGVVVDHGLQPGSREVAERAAEQLVGLGVDETLVLRPEVAGGGGVEAAARRARYQALRGALRDPRQLVLLGHTLDDQAETVLLGLGRGSGPRSISGMRALDPPWGRPLLGCSRAVTARACRELGLEPWTDPHNSDPRFTRVRLRREVLPLLEEVLQGGVAEALCRTSAQLREDGAALDQWADEVLSRAGSDQGHGALEVRAVEGAPVAVRRRVLRGWLISHGARELTDLHLRAVDDLVGRWRGQGGVWLPGGLVVERAHGRLQVGRPAG
>CP025990|2252700:2325731|2268422_2269808_-|AUS78559.1|DBSCAN-SWA
MSGLSGSDDERNRVGRGPVLWIGGCALALGATVLLLLSDDARLLRLGIVAGLWAALFGAFAAARYRREAAERADQSEELRRVYELELEREVAARREYELDLEAETRRQVEDELRAESQEQLAGLQRELETLRRGLESLLGGDVLVERVALRAESTRVRSLSDQGGRVISSGEQENPPVRALAVGARTVDDAAEVEPDPEARQGNPPPAPADRTQVIGGAPTGRPPAPGRPARGGPAPAGHPNDQGPPPPNPDHPRGGAPGPRRPQPAPSSPRGEPPVPAEQRQPPAGPDPATTRVPHPARPLEPGEDPRSAAGGPPRPPGRPGGRGPAPRPPAEPETVARPAPRRAPQGKQRQQRQQREEATRQLPRPQRPRRAQPPAPPKAQPVAAAAEAEAVEDTPAWEAVDAWQPDVAEETTPGPRESASEPPAEPEDAGAHASGRSVSELLAAYGEDKPRRRRRRGN
>CP025990|2252700:2325731|2277496_2278555_-|AUS78566.1|DBSCAN-SWA
MPARVDRTGPIAWDVARSTAVRLVGRGPQVPMEDALRAVSGLRELSGEAEGHVRELTGLGHDLPLREGLVLDRPGWASSAVEGMAALVDRAMPARRNAGLIAALASKAAGVQAGAVLAYLGGRVLGQYDPFGGDDGQGRLLLIAPNIVGVQRALRVPPADFQMWVCLHEATHRLQFTAVPWLRDHFATEVGTLLGSMDETVVGALDRLPELVRALRNRRSSDGGEPPALVELLQSPAQRAHLDRLLALGTLLEGHADHVMDAVGPRVVPSVRRIRARFTVRRRGGGLLDRALRVLLGVDAKVRQYAEGAAFTRHVVRRAGMDGFNAVWTSPETLPTRAEISEPAAWLRRVHG
>CP025990|2252700:2325731|2272964_2275514_-|AUS78564.1|protease|DBSCAN-SWA
MDRKRLLRNPFIWILLILLLIVGYNVLSDDTRGYHEVPTSQALEQIANGNVRTAQVEDKEQRLRLTLNSPVEGNEQIITQYPAGGTEQIVDALRGASGIDEWDTTVNQDSLFTQLLIYMVPLVLLLLLLLWMMNNAQGGGNRVLNFGKSKAKQLNKDMPKTTFSDVAGAQEAVEELYEIKDFLQSPGRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFEQAKQNAPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDSRGGIILIAATNRPDILDPALLRPGRFDRQIPVAAPDLAGRKAILRVHSKGKPLAQDADLESLAKRTVGMSGADLANVINEAALLTARQQGQLITSAALEESVDRVIGGPARRSRVVSDKERKIVAYHEGGHALAAWAMPDLEPVYKLTILPRGRTGGHALVVPEDDKDLMTRSEMIGRLVFALGGRSAEELVFHEPTTGASSDIDQATKIARAMVTEYGMSHRLGAVKYGKDEGDPFVGRTMGTQPNYSLEVAHEIDEEVRKLIEAAHTEAWEILNTYRDVLDDLVLELLEKETLQRRDLERIFSRVEKRPRITAFNDFGHRTPSDKPPIKSPAELAKERGEPWPPVPAVEAAPERPAAPEQGAGAVEEPSQQQPDQPAEGQPDQGPTQQAPPQQAPWPGGQAAPQPAVHPNHQATRPIPKPAGGSRSGPPNYGAPPGWTPATSPWTPQSSGWTPSWERGTNPNWEQQPSTSPEGESGGVAREPAAGEPSGAEKPDEGGTAPDTGDEGTRRFSRDELPGQQGPSAGSGQQEQPDDPRRGTRNDQEDGDGR
>CP025990|2252700:2325731|2323009_2323522_+|AUS78595.1|holin|DBSCAN-SWA
MSSAGHHSNGRWDGEGTPPIPSIPLSEDDRTDGAAGEKSIGNLVRQATVHMSTLIRAEVELAKQEITAEVKKGLRGSVYFVLALTVLAFSSFFLFFTFAELLAVWLPRWAGFGIVFLLMLLVAGFLAYKGYRRVRSIRKPERTISTVRETAAGFSGHRDRLDGGDPDRTG
>CP025990|2252700:2325731|2303264_2303900_-|AUS78582.1|DBSCAN-SWA
MDWSGGWRDAFRIELRAEAIGLAWRKWPVFPGSYLDGGQWVGGDAAAEHSGPVPVEPDWADHLLVDANRAASWWSVRPYSLLLATGYVVDAVEVDAPFGRRIASTLRRRHAQPVPIVATPDNTWLFLVAAGSTTPSRILAQPGVVLHGRGSWITLPPTPAEHGVVHWRVKPSVCGWKLPSVTLVEEAVAAAVRAEAQELRARGERLLTVRR
>CP025990|2252700:2325731|2261274_2262060_-|AUS81605.1|DBSCAN-SWA
MLLAIDIGNTNIVLGLYTGRGADATLLRDWRMRTDARMTADELALTMRGLLGEHADRITGVSALSTVPAVLRELRVMLGRYYSSVPRMLVQPGARTGVPLLVDNPKEVGGDRVVNTLAAHHLYGTACVVVDFGTSTNIDVISEKGEFLGGVFAPGMEISVDALASRAAQLRKVELVRPRAVIGKNTVECLQSGILYGFAAQVDGLVRRIVGELRSGGDTPVTVIATGGLAPLIVGETETIDHHVPDLTLVGLRLFYERNVH
>CP025990|2252700:2325731|2262623_2263541_-|AUS78555.1|DBSCAN-SWA
MTTDPAARPFRPGELTTHTDVEALSKVTRTLRAAGRRVTLVPTMGALHAGHRELIRHARRVPNSVTVVSVFVNPLQFGDGEDFDRYPRDLASDLEVCRSEGVELVFAPTAERMYPHGRSVSVRPGPLGDELEGAARAGHFEGVLTVVAKLFNIVRPDVAFFGEKDYQQLVLVRRMARELNLDTAVVGVPTVREPRGLALSSRNARLREDQRAAAVALSAALTAAVHTAGAGAATALATAREVLAAEPALDVDYLELRGPDLEPAPEEGSARLLVAARIGDVRLIDNAPLVLSRPDDTASGTTFAS
>CP025990|2252700:2325731|2305553_2305754_-|AUS78584.1|DBSCAN-SWA
MSPSRGPAQVLPASATTGEEGMSTAEYAIGTVAAAALAAVLYTLVTGDSVASALASLVQRALSVGF
>CP025990|2252700:2325731|2285459_2285699_-|AUS78570.1|DBSCAN-SWA
MLIMSMMSGTVIGIMVSWWVLTLVCPLARYVRRSRRRRRVVDRVRWELRAFRRGAVSPRGGASDVEVEGEREFGRRSAA
>CP025990|2252700:2325731|2286781_2287921_+|AUS78573.1|DBSCAN-SWA
MTGPPSFEELNEDADQRGWFDQAAARGSSWSGAYQDLQDATTPPEITAATITGRLELLEAIRSPGQALVGNGLGFLVSIVLSPLVEIAEWAIGDPEQMRATGEGWEQVARWLDEVSEAEGRRAEATEDSWRGEAGDAFRSRFAEFAEGVAALAADIRDLRQVLDLVADLFDAFVEFTIQLITELVIGLIVSWLAALAAAWITAGASVAAANVTTTIQVGSTGIRLTMRVTRLQQRIGQLVRRLEALLTRLRGPFRDLVNQAGSLRSGNAAQRFAMRRVDGNPLVNIFTRADGSTLASTTGNRFSAGVEGTQALATNISEAVLRNALGGQSRTSGAAMAAAGDQLTSAAIEQGAELAHDAATPEPSAEERRAAQERGFQW
>CP025990|2252700:2325731|2258358_2258709_-|AUS78552.1|DBSCAN-SWA
MAQKVTVTLVDDLDGSEAEETVDFALDGVAYQIDLSSNNASQLRDALASYVQGARRSGGRRRSAGRAPAGRSNGSTTTADREQNQAIREWARKRGMEVSDRGRIPAEVLEAYNKAN
>CP025990|2252700:2325731|2281275_2281764_+|AUS81609.1|DBSCAN-SWA
MEFDVTIEIPKGERNKYEMDHETGRIRLDRTLFTATQYPADYGFVDNTLGEDGDPLDAMVLVQEPTFPGCLIRSRAIGMFRMRDEKGGDDKVLCVPADDPRSEHLRDIHHLAEFYKLEIQHFFTVYKELEPGKSVEGAMWVGRAEAEAEIKRSYERLRTSDH
>CP025990|2252700:2325731|2270487_2270988_-|AUS78561.1|DBSCAN-SWA
MTRAVLSLGSNLGDRFAHLRSAVTGLGAAVVAVSPVYETAPWGVTDQPDFLNAVVVVDDAGVDAWGWLYRARELEEAAGRERTVRWGPRTLDVDVVTVDGVRSEDPELVLPHPGTPGRASVLVPWFDVQPEAVLPGHGPVRELLRSVSRAGVAVRSDLDLRGAAGR
>CP025990|2252700:2325731|2270987_2271365_-|AUS78562.1|DBSCAN-SWA
MTDRIRVTGVRARGHHGVFEHERRDGQDFVVDLTVWVDLSGAAATDDLRDTLDYGALAERIVAVVGGPPRNLIEGVAAQIADEVMADRRVHAVEATVHKPSAPIAVPFDDVAVTVRRSRRGGRGA
>CP025990|2252700:2325731|2263537_2264503_-|AUS78556.1|DBSCAN-SWA
MSAVVPGAAGEDASLGGRPARLATGVISAGRVGAVLGAALAKAGHVVVGASAVSSASRRRAEELLPDVPLLPPDQVARRSDLVVLAVPDDVLPGLVRGLVATGSLRPGQIVAHTSGALGVSVLRPAAEVGVLPVALHPAMTFTGRPEDLQRLATCSVAVTAAAGEPDEPSTSTAGGMGWHVGEALVVELGAEPVRVPEEARPLYHAALTHGANHLMTLVGDCLELLESSGVRESGRLLGPLLGAALDNALRHGDRALTGPVSRGDVGTVRRHLEVLSEAAPQVEPAYRLLAARTADRAERAGLLPPHVADDVRTSLDEEDR
>CP025990|2252700:2325731|2271361_2272186_-|AUS81607.1|DBSCAN-SWA
MPGRCAVMGVLNVTPDSFSDGGRYLDQAQAIHHGVEMHRQGADIIDIGGESTRPGSSRVDADVEIARVVPVIRELAALGVTLSIDTSRATVAEAALAAGAAVVNDVSGGLADPGMARVVAEAGAPWILMHWRGHSKGMNSLARYEDVVSDVRAELLTRVDEAVAAGVAPESLVLDPGLGFAKNAEHNWALLNRLDALLELGFPVLVGASRKRFLGAALADPDGTPRPPAGREVATATVSALSAAAGAWGVRVHDVVGSLDAITVERAWRAGGAR
>CP025990|2252700:2325731|2289849_2290326_+|AUS78576.1|DBSCAN-SWA
MREYEYEDEDDCADEDDDEEFAHINHYSGDVTNVVRARDIHGDVNYYERDHGVFHYRIFRYAGATLFLTLFVTAAAYSHLVNDMRLTWWEWALLPVVTAGLVLVMFHTHSWIYPNPSFRSFRAFLAIALIALGYNYGPQLDVVGDVSPVLAHWIVLRF
>CP025990|2252700:2325731|2264655_2265975_-|AUS78557.1|protease|DBSCAN-SWA
MRFGRERPGPEAVSFDYRPGARRRPWREVGGVAIDERTPVRHLTSARLERRRVLLWPVVVLVLLGVSGLALLGVATARVGFVPVIVGALLALLPVGPVLAAFLWIDRWEPEPPKLLLAAFVWGACGATGCALLINNTAEVVGESLLGTGGGDVVAAVISAPLVEEAAKALFVVGVFLRRRVEFDGIVDGIVYSGVTAIGFAFTENINYFGLAFREGGFGDLTGGIVAVFVLRGILTPFAHPLFSAMVGIGVGIAAGSRKKWVRTTALLVGYVLAVLLHAVWNGAATLGGGATFVDTYFVVMVPIFVATLVLVLWQRRREQRTVVAQLPGFAEEGWIAPGEVTLLSSLPSRKAWRKAVRERAGAEAARAVREYQHAVTELAFLRHRVAQGLPVPNAARRQAQAVGVLLGARAEAVRDGLVRSAATRAAHAERRRGTRPRR
>CP025990|2252700:2325731|2319030_2321031_-|AUS78592.1|DBSCAN-SWA
MTNDTGHSEAEHDAVTLDNLLRESREFPPSERFASQANATPDLYRVADRDRLAFWADQADRLRWETRWDEVLDWSDAPFARWFVGGRLNVAVNCVDRHVEAGHGDRVAIHWEGEPGDTRTITYADLRAEVSRAANALTELGLRSGDRVAVYLPMIPEAVVALLACARLGLTHSVVFGGFSAEALRARIQDAEAKLVITSDGQYRRGKALPLKSNVDLALRDAPSVRHVLVVNRTGADVEWTADRDLWWHETVDRQSPEHTPEDFDSEHPLFILYTSGTTGKPKGILHTSGGYLTQAAYTHHAVFDLKPETDVYWCAADIGWVTGHSYIVYGPLANGATSVMYEGTPNTPHEGRWWEIVQRYRVSILYTAPTTIRMFMKWGSDIPANYDLSSLRLLGSVGEPINPEAWIWYRQHIGGGATPVVDTWWQTETGAIMISPLPGVTATKPGSAMRTLPGISAEIVDETGEPVGPGGGGYLVLTEPWPAMLRGIWGDDERFRDTYWSRFADRGYYFAGDGAKYDEDGALWLLGRVDDVMNVSGHRISTTEVESALVSHAAVAEAAVVGASDPATGQGIVAFVILRGDATEHAGGDELVAELRQHVATVIGPIAKPRQIMVVPELPKTRSGKIMRRLLRDVAEKRELGDVTTLQDSSVMELISSGLGKPADD
>CP025990|2252700:2325731|2294991_2297721_-|AUS78580.1|DBSCAN-SWA
MAGSTRAKKGGGSRSGGSGGRRLVIVESPAKARKISSYLGRGFVVESSRGHIRDLPRGAADVPARYKSEPWARLGVNVEHDFEPLYVVTPDKKSTVSELKDALKDVDELYLATDGDREGEAIAWHLLETLKPKVPVRRMVFHEITEPAIRAAAANPRDLDHSLVDAQETRRILDRLYGYEVSPVLWKKVMPKLSAGRVQSVATRIVVERERERMAFVSADYWNIAAVLDGGPEAQPRTFQARLVNVDGDRLATGRDFGPDGRIRSGEVRVLAEDEARQLARGLDGAELTVSSVEEKPYTRRPYAPFMTSTLQQEAGRKLRFSAERTMRTAQRLYENGYITYMRTDSTTLSDTAITAARSQAAELYGDRYLSPQPRQYTRKVKNAQEAHEAIRPAGEVFRTPGEVAGELETDEFRLYELIWQRTIASQMADARGTTLSVRISGTARDGERCVFAASGRTITFAGFLKAYVESVDSEAGGEADDAERRLPVLTEDQRVTASSLDPEGHSTNPPPRFTEASLVKALEELGIGRPSTYASIISTIQDRGYVWRRGSALVPSWVAFAVVGLLERHFGRLVDYDFTAGLEDELDGIAAGRQERTAWLSDFYFGGDIGPSGSVGRAGGLKKLVGSGVEHIDAREINSIPMFTDADGRTVTVRVGRYGPYLEREAAPDAAGGEGAQRANLPEDLPPDELNPEIAEKLFATPMEGRSLGTDPDTGREIIAKEGRYGPYVTEVLGEDEKGKPRTGSLFKSMSLDTITLADALRLLSLPRVVGRDPETDTDITAQNGRYGPYLKRGTDSRSLDSEAQLFDITLEEALRIYAEPKKRGRRTAAAAPPLRELGSDPASGKPMVVKDGRFGPYVTDGETNASLRKADAVETLTDERAAELLAERRAKGTTPKRGRKRATSSKS
>CP025990|2252700:2325731|2317107_2318028_+|AUS81612.1|DBSCAN-SWA
MGQSAAQTEGSPLVRIRSLLPGLARAEQRVANVVLEDPAAVTHRSITEVAEAAGTSETTVTRFCKAIGIRGYPELRLALAADTARNAVRDEQKLGGEIGPGDDLHDVIGKVAYADARAVEETAEQLDPIALRKVVDRVSAARRVDVYGVGASAFVAMDLQQKLHRIGRVSFAWNDKHIALTSAAVLSEDDVAVGISHTGSTADVIEALRVARARGATTVAITNFPRAPITEVADHVLTTAARETTFRSGAMASRIAQLTLIDCLFIGVAQQHYETAQEALEVTYAAVVGQRLGSRPDGRRKARDGI
>CP025990|2252700:2325731|2278677_2280462_-|AUS78567.1|DBSCAN-SWA
MPSHRPGPPPTSTAPPTPANPDALPTVRTRVPTPAHGLPTPGGPDPLGRPTAAPDGDAATGRGGTTFMRPDPGPSAASSSSEETGDTPQAPVATAPEGVERAEESGGSPPPGGPPTEPPEDEEERPAPKGRGRLLAIGALALVVAVGTVTAFTVEPVGRFLGLRGPEVAPGPPAPPAVEPDPVLRALDLGASGPSAEGLTARLDQVGASPALGNLSGVVLDPASGETLWALDEAVPRTPASTTKLLTAAAILLTVEHDTTLETRVVQGEEPGTLVLVGGGDPTLSVLPRDTPTYNYPDAARLDDLVEQVQAATSEPVERIVVDASRYTGERLAPGVGESDVPGGHIAPVEPVMLDVDRQDPLLATTPRSSEPALAVGRALGERLGVPPDAVAVSREPVAGEGATVLGEVSSPSIERMVESMVLTSDNTLAETLARELAIATGHEPSFAGATTAILEVLAEHGLDVSTVALSDASGMSTENDISPAVLAELLAEAVGPDRPDEVAMMLRPMLPGLPVAGASGTLGGRYIDNAREGRGWVQAKTGTLTGVSTLAGIVTDVEGKLLVFALMSDGANTLEARAALDEMAAAIRTCGCR
>CP025990|2252700:2325731|2290775_2292020_-|AUS78577.1|DBSCAN-SWA
MTGSVEAVLGQPAVPTTGVWAEVVGQRSVLAELYAAAVAAAGAVSGGGTGGGAMTHAWLLTGPPGSGQTTVARVFAAALQCVVPGPVPGCGACQGCRTALAGTHADLRIVAPDGLSISVAEMRALVQTAARRPTAGRWQVVLVEDADRLTEGAANALLKAVEEPAERTVFLLCAPSDHPDDVPVTIRSRCRPLALGTPRPAEIARALRDHDGVDPELADWAASVCGGHVERARRLAADEAARQRRAAVLAIPTALHRSADVFRCADELVKAAETDAVEANEIRNEEEKEALRTAMGAGGTGKGTAAATRGANAAVRELEKRQKSRTTRTQRDSLDQALIDLTAFYRDVLVLSAGAAVPLNHPDREADSRSAAARWTPESTLRRLESVLECRDALAANVKPRIAVEAMLMVLWRG
>CP025990|2252700:2325731|2252700_2255259_-|AUS78550.1|protease|DBSCAN-SWA
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGIALEGVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVLQLLSGYQGKEPAETAGRGEGTPSSSLVLDQFGRNLTSSAREGKLDPVIGRDKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQQIVRGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHVEKDPALERRFQPIQVGEPSLDHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRYLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIADVRRDKESAIDAQDFERAARLRDEEKQLLAQKGEREKQWKSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSQAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGEDDALVQIDMGEFHDRYTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEVYNTLLQVLEDGRLTDGQGRTVDFKNTVIIFTSNLGTQDISKAVGLGFSGSGEQGSNYERMKQKVNDELKKHFRPEFLNRIDDIIVFHQLTESEIVRMVDLMVTRVETQLKNKDMALELTEKAKKLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGELQPGQIIIADVEGWDGEDKRDDEARFVFRGETKPVEVPDSPPVELSGSGGSSTENQNDTEND
>CP025990|2252700:2325731|2305970_2306699_-|AUS78585.1|DBSCAN-SWA
MTAVTIMVWAVAVVVAPLGWRVARRRLRTTSPVHERRVKILTNGPAVRAGAAAVVGFLLAEGPAALPVGVAAAVLTVLVDRWHAGRRRSRPPDPATLAATWDLLAACLRSGMSPPAAVRLASDELDHSDCRVVARPLRLVADLLVRGEDAATAWRPARAQPELRELATAVRRSASAGSALAETAERLARESRAAALDTAEADAQRAGVLVAAPLALCFLPAFLLLGVVPVLVGLAADVLSTW
>CP025990|2252700:2325731|2310670_2311501_+|AUS78589.1|DBSCAN-SWA
MTATKSAEQTTRPPRVAAFFDLDKTVIAKSSTLAFSRPFFQEGLINRRAVLKSAYAQFVFMLAGADADQTDRMRAHITSLCAGWDVEQVRSIVEETLHDIVDPLVYKEATQLIADHREQGHDVVVVSASGEEVVAPIARMIGADHSIGTRMVVTEGRYTGEIDFYCYGENKAVAVAELAETRGYDLGSSHAYSDSVTDLPLLGAVGHPTVVNPDRALRKEAAQRGWPSLTFDHPVSLRNKIPTPSGTAVAAAAVGLGAVAAAGVAWFGVRRRRNRG
>CP025990|2252700:2325731|2260460_2261240_+|AUS78553.1|DBSCAN-SWA
MDHVAVGSADDRRSDAAQAGSFGQVAQDYAEHRPGYPDLAVRWALEPVLSRPHVAVLDLAAGTGKVTRSVRGLAAETVAVEPDPRLRAEFTRRVPGVRVLDGNAEALPLPDASVDAVTVGQAFHWFDAPRALDEIARVLRPGGVVAALTNYNDDRREWVAGLQRTGIPSPGISEEDPDYVPAHPRFAPVETARFEHAHRRTAESLVQMISTHSWVLVQDPDERERMRAELRSYLAGRPETREGEFDLPQIAVVNRAVRR
>CP025990|2252700:2325731|2272319_2272946_-|AUS78563.1|DBSCAN-SWA
MTGTFEDLDGDLVAPTTGPGRFDQARAQAAIRELLIACGEDPDREGLVETPARVARAYREMFAGLHTDPDTVLSKTFDESHEELVLVRDIPMFSNCEHHLLPFHGVAHVGYIPNERGQVTGLSKLARLVDLYSRRPQVQERLTSQVADALVRRLAPRGVIVVIEAEHLCMTVRGVRKPGARTTTSAVRGLLRTSASSRAEALNLMRSG
>CP025990|2252700:2325731|2256803_2257655_-|AUS78551.1|DBSCAN-SWA
MTRPVPARPRSHDRPGPPDARLGARSLRLSYGERVVVHDLDLDVLDNTVTAVIGPNGCGKSTLLRALGRLLTPAEGTVLLDGKRIDRLPTREVARVLGILPQSPTAPDGLTVADLVARGRHPHQSWYRQWSSADEEAVADALRMTGMERLADRALDELSGGQRQRAWISMALAQGTELLLLDEPTTYLDLAHQIDVLDLVERLHTTRGRTVVMVLHDLNLAARYARRLVAMRGGEVVAEGEPAEVLTEDLLFHVFGLDARVIEDPVSGTPLVVPVGARHRTTV
>CP025990|2252700:2325731|2284478_2285306_-|AUS78569.1|protease|DBSCAN-SWA
MVPVAPRRRTWPVRALFLAAVVAALSTTAVSPAEPRREVAAAEEATSAEPAARIVGGVGGDEDYHFVVSIQRPTEGKDHWCAGALVDPEWVLTTAHCVQGELTAYTARVGTNHRSEGGSYERVVEMVTHPHWNGHTGDIALFRLARPVPAPTLPLAARRPPEGATVRILGWGKTCGTFECSWEYPELLRQLDVPVAAAAGCRAAGVDAATELCLRVSRDATSCYGDSGGPAVVREGGAWRLAGLDSRGGDPVCGVGGLVFTEVTVYRDWVRSVIS
>CP025990|2252700:2325731|2286003_2286444_+|AUS78571.1|DBSCAN-SWA
MTSGASDRVGHLLRSFEERARQVTELGQRLSGVRGVATSSSGVVTATVTPSGALVDLRLSPAATDRSHVALRQEILETVRAATRDAAERLEEMVGPVLGEDAQRIRDAVSSAGDFPVPRPDEDPPSAPRGDPGGGPSDEPPETFLR
>CP025990|2252700:2325731|2286452_2286785_+|AUS78572.1|DBSCAN-SWA
MTGFDVDPEALLAHGAGSERLADKFEELGALLDRARVDDQCFGPIGDALHLSGGYHSALEECEALATQAAGFLRTGAEMTRESAATYLGVDDGLARALESIGDTLRGGGR
>CP025990|2252700:2325731|2321278_2322019_+|AUS78593.1|DBSCAN-SWA
MTDPLAPLLGLPGVEEAVRRARADVDAVHRHPANRRGWATTGAEASVRAARASAGIEGAAVTLPDSGAVSDPVLAGSLRLAEALGGLLPTWQRAPGQVLARMHVLAAADLVDDAGRAGLGRPRADAGATDRLTLLAELVAGGTRAPAPVLVAVVHGELLALRPFGSADGLVARAAARLTAIATGLDPKGLVVPEVAFLRRRDDYRSAAEGFASGDPEAVGRWIQHCCAALTTGATEANAIADALAG
>CP025990|2252700:2325731|2307489_2308698_-|AUS78587.1|DBSCAN-SWA
MNPSTSTTAGERVRSGALVARTRRRLAESASPTTPTAIARAVRAEAGVVGHADVLHALRVLHQEFAGLGPLAELVRDTTVTDVLVTSPDEVWVDRGGGLVRADVSFDTEDAVRRLAQRLAAAVGRRLDEASPFVDAWLPETTSHGEVRLHAVLPPIVRSTSLSLRVLRPAAHTLAGLRASGTFDESIAVLLRQVVLARLSFLVVGGTGSGKTTLLAAMLGAVPPGERVVCVEDAHELRPDHPHFVRLVVRPPNVEGAGRISTRDLVRQALRMRPDRLVVGEVRGEEVCELLAALNTGHEGGAGTLHANSPAEVPARVEALAALGGLGRAALHSQLGAAVRLVLHMVRLPGGDRVLDSISVLAKETDRVVVTPAWRRGAGRGPAWEDLAELVRHRGGWASCSA
>CP025990|2252700:2325731|2315463_2316744_+|AUS78591.1|DBSCAN-SWA
MTVRATLSTLCVTAVFLASGLGWGVGETSASSSWSAESCPTLREGSPEELGLDSTPLVETADRLRRWAEPATGRPLFAGAAVLYAHQNVVLRRDSAGYALRYADGEGRELPGEEQRPAGTGTVFDIASLSKLFTSVLVMRQVEEGALLLDAPVSRYVPEFGDNGKERVTLRQLLTHTSGLEPFLPLWRDWPDRESRLRAVLAVRPQVPPGSAYVYSDLNMIALMVVLERVTGLPLDELLRRDVTEPLGLAGTGFRNADDPVGDVAATEYQVVPARGMVHGEVHDENAWSLGGVSGHAGMFSTIDDLAVFGQTMLNGGCYGGARILRPSTVRQMLTNHNDAFPSNPRGLGFELDQPFYMGGLSGPLTAGHTGYTGTSLVLDPLSNSVVVLLTNRVHPSRDWGSINPARAAVSDALASVVGRGDGNSP
>CP025990|2252700:2325731|2322025_2323003_-|AUS78594.1|DBSCAN-SWA
MVPCRRTPARATRVISTWARWRSAGRPKRNRRGELGNRCPRRAGRPAYVARVSENAADERTLDGVPWAKLVIIGLVAGALSGLFGLGGGVAIVPLLVTLVGFDQRQAVATSLLALAPLSVAGAASYAWHGQVNLWMAVPLAVGCMTGAWLGASLLNRAPLALLRWAYAVVSICTAVYLLVGPAPQVSSDVGPGWPLLWLLPIGLAIGVLSALTGIGGGAIMVPVMQLGFAAPAAMAKGTSLLVITPTSILGGARALRKGNGSLRASLWIGCSGVLATVAASQWSVVMDQRLSDRLFAALLVFVALKTVWGDLRALLRRRPPRSDR
>CP025990|2252700:2325731|2312341_2314120_+|AUS81611.1|DBSCAN-SWA
MGAALLAGCAGGGTSDGSESAAPGGGEAADAMTEWIDETIAGMSLEEKVGQLFVTYVYGTSADTAHDSNLEEFGLATPAEIIQRYHLGGIIHFSWTDSLESPRQVAELSNGVQDAALSSGAGVPLTISIDQEQGAVLRFGAPATEFPGSMALGAGRSVEDARAAAAITGQELRAVGITQNFAPVADVNVNPANPVIGVRSFSSDPELAADFVTAQVEGYQDSDAPERTVSSSIKHFPGHGDTNVDSHHDLPVIEHTREEWEELDAPPFRAAIEAGADSVMSGHLMVPGLDDSGMPATLSPTILTGMLREELGFDGLIYTDSLQMEGVRSQYPDDRIPVLALLAGADQLLMPQHLDVAVQGVLDAVGSGELTEERIEESVRRVLRAKWDRGIVAEPHVDPDHAEAFVGSEEHLATAREITDRTVTVLRNDADLLPLDSAPGSVLVAGWDEATTAALAEGFGERGATTTTLPNDFQPSREQIGRATAAAGEHDLTVVLTNGAWQDARSGQRDLVRELVATGQPVVAVAVRDPYDAAYVEEAGTWVATHSFNRVTMGSLARVLLGETSPRGSLPVSVPEPAGSGDRFPFGHGLSW
>CP025990|2252700:2325731|2287923_2288631_+|AUS78574.1|DBSCAN-SWA
MLAARHTWCAPSERIRLATPLGARLRFDVAGMDEHGAPRRGWLARTSGAVGGAAGGALLGLVDALSGNDNLSSDPGQVPTTLVTGPGPECLAVSTLSGVDTLAPGDHWFLTSTRLALLSFLPSGTEATGSTSGTPAEAGTGLLDRARRFGTGILGNGDPAAPPLRGSLPLATARVELPASRVRSVGVVARKQGGGSSGVPPHYLRVVLDDGSAFELAAPGRTEAAARRMLALASS
>CP025990|2252700:2325731|2269961_2270444_-|AUS78560.1|DBSCAN-SWA
MRFTRARDLLAVGLGSLLVVYLLLTLFYSSLPRLPTFAGATLVLIGAVEAVLGFSIRVRVRERDRRGAVPRELALFAARAVALAKASSLLGVIMLGAWLAVLLYVSPHRGDFDAAAGDQVTSLIGIACAVLLAAAALWLEHCCRAPEDPDSDEDRNNHDD
>CP025990|2252700:2325731|2294472_2294886_-|AUS78579.1|DBSCAN-SWA
MFGDALTGPDGTQAPPAPPPRTDAAGGPVTAWTAVRPGEPGAVAAPVAAVRPPEPSERMRRAAEREGGLWGAAPRPSQSRAPHRESVSPEVWAESAAGSYPMPEVIAERPGPTPHRLLPLVMALLMLAVIIGAHWVS
>CP025990|2252700:2325731|2298327_2300646_-|AUS78581.1|DBSCAN-SWA
MSRLHLAQSTWAQGLELSGGDYGVVAVVAVVALAALAVGYFLLREVLAAGQGSSKMQEIAVAVQEGATAYLSRQFRTLGVFVALVFLLLFALPAEDANERIGRSLFFVIGAAFSAAIGYLGMWLSTRANLRVAAAAGEPGGREKATRIAFRTGGVVGMTTIGLGLLGAAVVVMVYAGQAPKVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQNIPEDDPRNAATIADNVGDNVGDCAGMAADLFESYAVTLVAALILGTAAFGTHGLLFPLIVPAIGVLTAVVGVYTTKARQGENGLRAINRAFYLSAAISAVLSVIAAFVYLPSTFAELTGGENTTEGNPALIAAAAVLIGIVLAGVILWLTGRFTGTEHRPVRDVGRSSRTGAATVILSGISVGFESAVYTALVIGAAVYGAFLLSGSITVALFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGIAEMAGDSDPEAARILTDLDAVGNTTKAITKGIAIATAVLAATALFGSYTDAIQTALAGIAGVVTFDLSGFLVFNPGLLVGLVIGAAVVFMFSGLAVNAVSRAAGAVVMEVRSQFRNNPGIMDGTVRPQYGRVVDICTKDSLRELATPGLLAVFAPIAVGFGLGVGPLAGYLAGAIGAGTLMAVFLANSGGAWDNAKKLVEDGHHGGKGSDAHAATVIGDTVGDPFKDTAGPAINPLLKVMNLVAVLIAPAVVTLSVGDGASPVARALIALASVTIIVVAVVISKRRSTAIGEEAPEETRDPANTTA
>CP025990|2252700:2325731|2324546_2325731_-|AUS78597.1|protease|DBSCAN-SWA
MNWVDAAVLVAVVLGAISGVRHGMAVAICAGLGVAGGAVGGLMLAPWVADQLEGPSVQLAVALSILFSLVVIGQLAGVYVGRSIKRRLGHSRLSRVDNFLGGVVQGLMVVLVAWLVALPITSAASVPWLAAAVKESRVLGTVDDVMPPEAKGLPNELGRLFAFSGFPHVLDPFSRTPAAEVDPPDPELQASATVRRVRESVVRVHGQARSCQRLLNGSGFVVAPHRVMTNAHVVAGADQVTVEVERASLRATVVLYDPSRDVAVLDVPDLYAEPLDFAPDPAATGDGGIVLGYPLGGPYTASAARIRQRMTLTGPDIYDQNTVEREIYTVRSAVRSGNSGGPLVDPDGRVLGVVFGAAADQSETGYVLTNAEIDEDVRTATGLTDEVPTGECSA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUS78550.1|2252700_2255259_-|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	3.9e-131	39.7
AUS81603.1|2255818_2256703_+	iron-sulfur protein	NA	NA	NA	NA
AUS78551.1|2256803_2257655_-	cobalamin/Fe3+-siderophore ABC transporter ATP-binding protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	2.4e-08	25.3
AUS78552.1|2258358_2258709_-	Lsr2 family protein	Q854K3	Mycobacterium_phage	3.8e-13	37.3
AUS81604.1|2258882_2260346_-|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	1.3e-67	34.9
AUS78553.1|2260460_2261240_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AUS81605.1|2261274_2262060_-	type III pantothenate kinase	NA	NA	NA	NA
AUS78554.1|2262103_2262589_-	aspartate 1-decarboxylase	NA	NA	NA	NA
AUS78555.1|2262623_2263541_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
AUS78556.1|2263537_2264503_-	DUF2520 domain-containing protein	NA	NA	NA	NA
AUS78557.1|2264655_2265975_-|protease	protease PrsW	NA	NA	NA	NA
AUS81606.1|2266042_2267083_+	hypothetical protein	NA	NA	NA	NA
AUS78558.1|2267263_2268412_+	NADH-quinone oxidoreductase subunit D	NA	NA	NA	NA
AUS78559.1|2268422_2269808_-	hypothetical protein	NA	NA	NA	NA
AUS78560.1|2269961_2270444_-	DUF3180 domain-containing protein	NA	NA	NA	NA
AUS78561.1|2270487_2270988_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4VNV0	Pandoravirus	1.3e-14	39.7
AUS78562.1|2270987_2271365_-	dihydroneopterin aldolase	NA	NA	NA	NA
AUS81607.1|2271361_2272186_-	dihydropteroate synthase	S4VNV0	Pandoravirus	1.4e-21	33.0
AUS78563.1|2272319_2272946_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	9.7e-44	51.4
AUS78564.1|2272964_2275514_-|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	1.1e-109	48.8
AUS81608.1|2275851_2276406_-	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	1.8e-09	27.9
AUS78565.1|2276469_2277462_-|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
AUS78566.1|2277496_2278555_-	coenzyme F420 biosynthesis-associated protein	NA	NA	NA	NA
AUS78567.1|2278677_2280462_-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
AUS81609.1|2281275_2281764_+	inorganic pyrophosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	5.8e-28	44.5
AUS78568.1|2283606_2284035_-	hypothetical protein	NA	NA	NA	NA
AUS78569.1|2284478_2285306_-|protease	serine protease	G9E4F4	Emiliania_huxleyi_virus	8.4e-11	30.1
AUS78570.1|2285459_2285699_-	hypothetical protein	NA	NA	NA	NA
AUS78571.1|2286003_2286444_+	hypothetical protein	NA	NA	NA	NA
AUS78572.1|2286452_2286785_+	hypothetical protein	NA	NA	NA	NA
AUS78573.1|2286781_2287921_+	hypothetical protein	NA	NA	NA	NA
AUS78574.1|2287923_2288631_+	hypothetical protein	NA	NA	NA	NA
AUS78575.1|2288667_2289345_+	hypothetical protein	NA	NA	NA	NA
AUS78576.1|2289849_2290326_+	hypothetical protein	NA	NA	NA	NA
AUS78577.1|2290775_2292020_-	DNA polymerase III subunit delta'	S5WKH4	Pseudomonas_phage	8.2e-10	30.7
AUS78578.1|2292090_2294118_-	thymidylate kinase	NA	NA	NA	NA
AUS78579.1|2294472_2294886_-	hypothetical protein	NA	NA	NA	NA
AUS78580.1|2294991_2297721_-	type I DNA topoisomerase	J3E777	Acanthamoeba_polyphaga_lentillevirus	1.1e-99	31.5
AUS78581.1|2298327_2300646_-	sodium-translocating pyrophosphatase	NA	NA	NA	NA
AUS81610.1|2300865_2303238_+	DEAD/DEAH box helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	3.3e-07	26.5
AUS78582.1|2303264_2303900_-	DNA primase	NA	NA	NA	NA
AUS78583.1|2304343_2304685_-	hypothetical protein	NA	NA	NA	NA
AUS78584.1|2305553_2305754_-	DUF4244 domain-containing protein	NA	NA	NA	NA
AUS78585.1|2305970_2306699_-	type II secretion system protein	NA	NA	NA	NA
AUS78586.1|2306695_2307580_-	hypothetical protein	NA	NA	NA	NA
AUS78587.1|2307489_2308698_-	ATPase	NA	NA	NA	NA
AUS78588.1|2308694_2309795_-	hypothetical protein	NA	NA	NA	NA
AUS78589.1|2310670_2311501_+	HAD-IB family hydrolase	NA	NA	NA	NA
AUS81611.1|2312341_2314120_+	beta-N-acetylhexosaminidase	NA	NA	NA	NA
AUS78590.1|2314126_2315467_+	DUF1343 domain-containing protein	NA	NA	NA	NA
AUS78591.1|2315463_2316744_+	serine hydrolase	X2KYU1	Mycobacterium_phage	8.4e-10	31.3
AUS81612.1|2317107_2318028_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AUS81613.1|2318033_2318960_+	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
AUS78592.1|2319030_2321031_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	8.9e-83	39.8
AUS78593.1|2321278_2322019_+	oxidoreductase	NA	NA	NA	NA
AUS78594.1|2322025_2323003_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
AUS78595.1|2323009_2323522_+|holin	phage holin family protein	NA	NA	NA	NA
AUS78596.1|2323534_2324491_+	alpha/beta hydrolase	NA	NA	NA	NA
AUS78597.1|2324546_2325731_-|protease	serine protease	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>CP025990|4572796:4616063|DBSCAN-SWA
GATGGGGTCGGTGCAGGACGGCCGCGATCCCGGCCTGCACGACCGCTACTGGGAGGCGCAGCTGGAGGCGGGCGCCCGGAACAGCCTCCACTGGGGATTCCTGGCGTTCTTCGTCGGCTGGGCCGCCTACTACCTGGTGGCCGGGTTGATCGGGGCCATCCTCGCCGGGCAGTTCCAGGAGTTCGACCCGCTGGCCCCGCCACCGATGGGGCCGCTGCTGCTCGTCTCGCTCATCCCCAACCTCTTCCTCGGGCTCGGCCCTGCCGTGCTGTCCTGGTGGAAGGGCCAGGGGCTGCGTCGCGACTTCGGCATCGTGCCCAAACGCCGCGACTGGAAGGTCGGGCTGCTCTCCGGGGGCATCGGCCTGGTCGCCGCCTTCGTGATGGCGATCCTGCTGATGTCGGGATCGCTGGACGAGAACGGCGAGTCCTCCGGGATCAACAGCCTCGGCCAGCTCGCCCAGGGGCAGGCGATCTGGATCCTGCTGTTCTCGCTGTTCGTCTTCATCGGCGCGCCGCTCACGGAGGAACTGCTCGTGCGCGGCGCGTTGTGGGGCGCCTTGGAGCAGTACCGGGTACCCCGGTACGCCATCCTGCTGCTCACGACCTTCGTGTTCGCGTTGATCCACGAGGAACCGGAGCGCACCCCGGTGCTGCTCGTCGGTGGGCTGGCCATCGGCATCGCGCGGATGATCACCGGCCGGGTCGCGGCCGCGATCATCGCGCACGCCACCTACAACCTGCTGCCGGCCGTCGTCTTCTACGCGCAGTTCAGCGGCTGAGGACCCGCCGGCACTACCCAGCGTGGCTGGCGTGATCACACCACGAGACCACGGCCCCGCCCTGTTCGGCGTGCCGCGATCACGACGAGTGCGGCTAATCTCGGTGGGACGGGGAAGCGGAGTGGGGAGATCACAACGTGAACCAGGTCGACGGTGGCGAGGAACCTCGCCGCGCAACTCCCGGCCCGCCCGGGCACGGGACGGCTGAGCCCGACGAGACCGTGACCGACATCCCCGGCGAGGAACGGGCGACCAGGACCGCCGGCCCGGGGGCCGAGGCCCGGCGGGACGGGGGACCGCCCACCGCCGAACCCCGGCCCGACCCCGGCGCCGACGGGGCGCCGGTCCGCACCCACCGCTGGGGACTGGGTGTGTTCTTCCTCGCCCAACTGGTGTTCCTCCTCTCCTCGGTCTTCCTGGTCGCCCCGTTGGGACCGATGGACCCGGACTCCTCCCTCCGGGAGACGGTGCTCATCGTGGGGCTGGTCCTGCCCACCCTGCTCGCGGCCGGGGTGGTGCTGGCCGCGACCCGTCTGCGGGGCAACGGCCCCCGGCGCGACCTCGGGCTCGAGTGGTCGTGGGCGGACGTCCGCACCGGCCTCAAGTACGGGGCGTTGTGCATGGGGCTGGCCTACGTGGGGGCGATGTTCTGGTCCCAGTGGGTGGGGGAGGAGAACGCGAACTCCGCGGTGGGATCGCTGGTCGAGGGGCTCCAGCTGTCCCCCGGCCTGGCGGTCCTGCTGTTCCTCCACGTCTTCCTCATCGCACCGACCTGCGAGGAACTGATCTTCCGAGGCGCGCTGTGGGGAGCCATGGAGCGGCTCAGGTGGAGCAGGTGGACCGTGTTCGTCTCCAGCACGGCGATCTTCGCGGTGGCCCACCTCGAGCCGGAGCGCACCCCGCTGCTGCTGCTCATCGGCATCCCGATCGCGCTCGCCCGCCTGTACACGGGACGACTGCTGGCCAGCATCGTCGCCCACCAGATGAACAACCTGCTCGGCGCGGTGGGGCTGCTGCTGATGGCCCTCGGGGTGATCCCCCCGTGACGCACCGCGCGGACGTGGCTCCCCCCGGGGCGGTCGGCGGCGCTCCGGCACGACCCCGTCCCGGTGGCTTCCGAGGTCAGTTCGGCTCGCGGGGGACCATCTGGCAGAATGGCTCGCTGTCCGTCGCTGTCGGGCCCTCTCACCGTGCAGCGGCTACCCATGACGTCCGAGCGCTCGGACCCGTCGCCCCACTCGGGCCACGGGCGCTCATCCATGAGCAGACGAGAGCTTGAGGAGCAACTCACCCGTGGCCGTCAAGATCAAGTTGATGCGGCTCGGCAAGATCCGCGCCCCGCACTACCGGATCGTCGTCGCCGACGCCAGGACCCGCCGTGATGGCAAGGCCATCGAGACGATCGGCAAGTACCACCCCACCCGCGAGCCCAGCTTCATCGAGGTGGACTCCGAGCGTGCCCAGTACTGGCTGGGTGTCGGCGCGCAGCCGACGGAGCCCGTGCAGCGGCTCCTGGAGCTGACCGGCGACTGGCAGAAGTTCAAGGGCCTCCCCGTCCCGGAGGGCGCCCTGAAGCAGGCCGAGCCCAAGCCGGACAAGCAGGCGCTGTTCAACGCCGCGCTGGCCGCCGCCGGTGAGGAGCCGGTGACCGAGGCCACGACGCCGAAGAAGAAGTCGACGAAGAAGAGCGACAAGGCCGACGCGTCCGAGGCCGAGGGCGAGAAGAACGAGGGCGGCCAGGAGTGAGTGTCCTGGCGGACGCCCTGGAGCATCTCGTCAGGGGCATCGTGGCGAACCCGGACGATGTCCGGGTCCAGCTCATCACCACCCGGCGGGGACGCACCCTCGAGGTGCACGTGCATCCCGACGACCTGGGCAAGGTCATCGGCCGTGGTGGTCGCACCGCGACCGCCCTGCGGACCGTGATGGCCGGCATCGGTGGCCGCGGTCTGCGGGTCGACGTGGTCGACACCGACAGGTGAGCGTGGTGTGGCAGTGGTGAACACCGCCAGGCTAGGGGAGTCCGCCCTCCTCGTTGGCCGGGTCGTCCGCCCGCACGGTGTCCGTGGGGAGCTGGTCGTCGAGGTCCGGACCGACTCCCCCGAGGAGCGGTTCGCCGTCGGCACCACGCTCGACGGTCGCCTGCGGGACGGCAGCACCCGGACCTTCACGGTGACAGCCGCCCGGAACCATTCCGGGCGGCTGCTGCTCACCCTCGACGGTGTCGTGGGGCGCGACGCGGCGGAGGAGCTGCGCGGCACCCTGCTCACCGTGGACCGCGCGGCGCTGCCCCCGACCGGCGATCCGGACGAGTACTACGACCACCAGTTGGAGGGTCTGCGGGCCGAGCTCCCCGACGGCAGCGAGATCGGTCAGGTCGTCGAGGTGGTCCACGGCGCCGGCGCCGACCTCCTCTCGATCCGAGCCCCGGAGCGGGCCGACCGCGTCCTCGTCCCCTTCGTGCGGGCGATCGTGCCCGAGGTCCACCTCGACGAGGGGCGGTTGGTCGTCGACCCGCCCGAGGGGCTGCTCGACGAGACCTGAGGGCCCGCCGTGCCGCGAGCCGTGGCCGCCGCCGTGCCGGGGGTGGGTGCGCGTCCTCGCGGTTCGGCGTCCGATCCTCGCGGTTCGGCTCCGAGGCGCCGCTCCTCCCGGTCGCCCGGGTCGATCCCGTCCCCGATGACCGCATCCACCCCCGTGAACGTTCAGGGAGCGCCGTTGCGCATCGACGTGATCACCATCTTCCCCGAGTACCTGGCGCCACTGCGCGCGGCACTGCTCGGCAAGGCCGTCGACCGCGGCCTGGTGGAGATCGGCGTGCACGACCTCAGGTCCTGGACGCACGACGTGCACCGCACCGTGGACGACAGCCCGTACGGTGGCGGGCCGGGCATGGTGATGAAGCCCGACGTGTGGGGCGAGGCCCTTGACGCGGTCTGCCCGGCCCCGGACCCCGAGGACGCCGGGGGCAGGGCTCCTGTCCTGGTGGTCCCCACCCCGGCGGGACGCCGGTTCGACCAGGCCCTCGCCCGCGAGCTGGCCGAGGAACCGAGGCTGGTCTTCGCCTGCGGGCGGTACGAGGGGATCGACCAGCGGGTGGTCGACGAGGCCGAGGGGCGGATGCGCGTCCTGGAGGTCTCCATCGGTGACTACGTGCTGGTGGGCGGGGAGGTCGCCACCCTGGTCATGGTCGAGGCGGTGGCACGGCTGATCCCCGGCGTGCTGGGCAACCCCGTCTCGGCGTCGGAGGACTCCTTCTCGGACGGCCTGCTGGAGGGCCCCTGCTACACCCGTCCCGAGGTGTGGCGGGGCAGGGCGGTGCCCGACGTCCTGCGCTCCGGCAACCACGCGGCGGTGGACCGGTGGCGGCGGGACCGGGCGCTGGAGCGCACCCTCCGTCGTCGACCGGACCTGCTCGACGCCCTGCCGCCGGAGGAGCTCTCCCGTGCCGACCGCGCGTTCCTCGCCGGGCTGGAGGAAGAGTCTCCGCAGGTCGGGGCCGATGGTGGCGGCGCGGGAGCCGGCCCGATTTCCTGAGACGATCCCGCCCGTGGCACACTGGGTGGGTTGCTGCAACCGGCAGACCAGCCGGCGCGCACCACAGACCACTCCGACGGCGAGCCCAGGCTGTGCCGACAGCGCGCGGCCGCGCCCCGCGGAGAGACGAAAGACCCGAGTGAATGGTGAGGACGGACCACCGATGAACACCCTGGACGCTCTGGACGCTCAGTCGCTGCGTTCCGACATTCCCGCCTTCCGGCCGGGCGACACGCTGAAGGTTCACGTCCGCGTCATCGAGGGCTCTCGGGAGCGCGTGCAGGTGTTCCAGGGCGCCGTCATCCGGCGTCAGGGCGGCGGCATCCGCGAGACCTTCACCGTGCGTAAGGTCTCCTTCGGCGTCGGCGTCGAGCGGACCTTCCCGGTGCACTCCCCGAACATCGCCAAGATCGAGGTGGCGACCAGGGGTGACGTGCGGCGCGCCAAGCTGTACTACCTGCGTGAACTCCGCGGCAAGGCCGCCAAGATCAAGGAGAAGCGCGAAACGCCGACGGCCTCCTGAGTCCCTTGTGGATCACGTAGCGTAGTCTGAGGCGGTGGCGGACTTCGTGCCCTCGAACACACCCCAGGGCGATCCAGACCAGCCCAAGCCCGACCCAGCGCCTCGGCCCGGCTCCGAGCAGGGCCCGCCGTCCGACGGTGGGCGACATAGCTCGGAGCCGGTGAGCGACGAGGCCACCGCTGGCGAGGGCGCGGGCGGTGCGGGTGAGAAGGAGCAGAAGAAGGGCTCCTTCTGGCGCGAACTGGTCGTCCTGGTGGGCATCGCCGTGGTGCTGACCATCGTCATCCAGGCCTTCATCGCCCGGGTCTACGTGATCCCCTCGCAGTCGATGGAGGAGACCCTCCATGGCTGCAACGGCTGCACCAACGACCGGGTGCTGGTGGACAAGATGACCTACCGGTTCACCGACCCGAGCCCTGGCGACGTGGTGGTGTTCCGGGGGCCGGCGACGTGGACCGAGAACGAGATCCCTCCGCAGCGGTCCGACAACCCGGTGGTGAGCTTCTTCCAGTCCATCGGTGGGCTGGTGGGCATGGCGCCGCCGGACAACCGCGAGTTCGTCAAGCGGGTGATCGCGACCGGCGGGCAGACCGTCGAGTGCTGCGACGAGGAGAACCGCGTACTCGTCGACGGGGAACCGCTGGACGAGACCTACGTCTACTGGCAGCCGAACCGGGGTAACACCCAGGAGGCCTTCGGCCCGGTCACCGTGCCCGCCGACCACCTCTGGATGATGGGCGACAACCGCAACAACTCCCTGGACTCCCGAGTGCAGGGCGGCGGTGGTGAGCGGGGCTCGGTGCCCGTGGACGACGTGATCGGCAAAGCCCGGTTCATCGTGCTTCCCCCGCAGCGCTGGCAGGGCATCGGTGACGATGATCCGCAGCGGACGGGGCAGGCGCTGAGCGCGCCGGCCTGGCACGGCGCCATCCCCGCCGGGATCGGTCTCGCGGCCGCCTTCCCGACGTTGTGGATCGGACGGCGGCTGCTCTCGCTGCGTCGGCGGGACGACTGACGGCTGGGACTGGCATGGTGGACGCCGAACCAGGGTTACCGCGGCCGCCCAGGGCCGTGGTCCGGCGGAGTCTCGGCAACTGGGCGTTGCAGTCCGCGCTCGACCGGCGCGGGCTGGGCCCGGTGGCCGGGGTGGACGAGGCCGGTCGCGGGGCCTGCGCCGGCCCGCTGGTGATCGCGGCCTGCGTCCTCCGGCCCAGGGACTCGGAACGCCTGCCCGGGCTGACCGACTCCAAGCTCCTCACCGCCCTGGCCCGGGAACGGCTCTACGACCAGGTGGTCGACCGCGCGGTCGCGTTCTCGGTGGTGTCGGTGCCGGCGGAGCGGGTCGACACGCTGGGGGTGCATGTCGCCAACCTCGAGGGCATGCGCCGGGCGGTGGCACGGCTTCCGGTGCATCCCGGGTACGTGCTCACCGACGGGTTCCGGGTGCCCGGCCTGACGGCGCCGAACCTCGCGGTGGTCAAGGGCGACCTGGTCGCCGCGTGCGTGGCGGCGGCCTCCGTGCTGGCCAAGGTGACCCGGGACCGGGCGATGGCCCGGATGGACCAGCGGTACCCCGGGTACGGTTTCGCCGTGCACAAGGGGTACTGCACGGCGGACCACGCCGAGGCCCTGAGGGAGTACGGTCCGTGCGCGGAGCACCGCTTCTCCTACTCCAACGTTCGGGAGGCTGCCGGTCACAGGGTGACGAGCAGTCGAACGTCGCCGGTCGGAGGGGGTGCGCCAGAGCCCGTGGCGATCAGCTGATGGTCGCCGCTCGTGTTGAGGAAGAGTGTCGTGGACAATGAGGCCCGCATCACCGGTGCTTCGGCGGTAGGGAGGGTTCGGACTCGATGAGTTCCGAGGATCTCGAGAAGTACGAGACCGAAATGGAGCTGCAGCTCTACCGGGAGTACCGCGACATCGTCGGTCAGTTCTCGTACGTGGTGGAGACGGAGCGGCGGTTCTACCTGGCCAACGCCGTGGACGTCCAGGTGCGCAACTCGGAGGGCGAGGTCTACTTCGAGGTGCGGATGTCCGACGCCTGGGTGTGGGACATGTACCGACCAGCCCGTTTCGTGAAGAACGTCCGGGTCATCACCTTCAAGGACGTCAACGTCGAGGAACTCGACAAGCCCGAGTTGCGGCTACCCGAGAACGGCCCCTTCTCCTCCGGCTGACGCGGCGCGTCGCCCGGTCGCGGCGTGGCGGGGCCCCGATCCCGGTTCGTCCGGACCGGAGTGGGACGGCCAGCGGGACTCGGGTCGCCCCGGCCGAGGCGCGCGGGGACGCGAACGGAACCCCGTCCCACCGCCAGGCTGACGCCTCTGGTGAGGCCGGGGAGGGGAGCCGGTCCCCCGACCGGGACGCCCGGCCCGTCCCCTCCGGGGAGGAGCGGCCGGGGGAGGGGAGGCCGCGAGGCCACCCCCCGAGGCACCGGCGGCCAGGACGGGTGGCGCCCGTCGATCCCTCCCCGGCGACCGCGCGGGTCGGCTGGTCAGACCTCGGCCGACTTGGGAGGGTGGACCAGGTGCACCCCCACGATCCCCCGAGGTCCCCGTCGAGCCCAGCACCCGACGGGGCGGAAGCGCCACGACGGCCCGCCTCGGACCGGGGCGAGCGCGCTCCCCTTCCCCGCGGCGACGGTGGGGCGACCGCCCAGGCCGCACCCCGCCCAGCCGTGACCGGACAGGCGGAGGCCGTCTCCTCGACGACCGCCGAGCAACTGCTGGCCGACTACCGACGGCACCTGCGCGCCGAACGGAACCTGTCGGCCCACACGGTCCGCGCCTACCTGGGCGACCTGCGCGAGCTCCTCGCCCAGCTCCCCGGAGCCCCCGACGCCGTACCGCTCGACCCGCTCCCGCTCGACATCACCCTGCTGCGGGCCTGGCTGGCCACACGCCACGCCGAGGGGGCCAGCAGGAGCACCCTCGCGCGCCGCGCCGCCGCCGCCCGAGCCTTCACCGCCTGGGCCACCCGGCGAGGCCTCCTCCCCTCCGACCCCGGGCCTCGGTTGCGTGCTCCCCGCGTGCGGCGCGCGCTGCCCTCCGTCCTGCGCCCCGACCAGGCGGCGACGGCGCTTCGCGCGGCGGAGCGGGCCACCGCCGACGGCGACCCGGTGGCGCTGCGTGACCACGCCGTGGTCGAACTCCTGTACGCGACCGGGGTCCGGGTGGCCGAACTCTGCGCGCTGGACGTGGACGACGTGCGGCGTGCGGACCGTCTCCTGGTGGTGCGGGGCAAGGGCGACCGGGAACGCGCCGTGCCGTTCGGTGTTCCCGCCGAACGTGCGCTGGCGGCGTGGCTCGAACGAGGACGACCCAGCTTGACCAGGTCGGATTCGCCCCCAGCCGTCTTCCTCGGGGTGCGCGGCGGTCGACTCGGCGTCCGGGCGGCACGCACGATCGCGCACCAGACCGCCGCGGCGGCTCCCGGCGCTCCGGACGTGGGACCGCACGGATTCCGGCACTCGGCGGCCACCCACCTCCTCGAGGGCGGGGCTGACCTCCGCAGCGTACAGGAGTTGCTCGGTCACGCTACGCTCGCAACAACCCAGTTCTACACACACGTCACCGTCGAACGGCTAAAGGCAATCCATGACCGAACCCACCCCCGTTCCTGACGATGTTGGGGGAGGTTCCCGTACGGCCATCGCGCGTCACCAGCAGGAGCATGGCGCCACGGTCGGTGGCGACCGCGCCATCCGCTCAGCTCGGTCGGGGACTGCTCCAGCGACACCCTCACAGCCAGCCCAGCCCACCGCCGGGTCGTACCGCTCCCGCGTCACTCGGCGTGACGCCCCGTCCTCCGGTGATCCGCGCAGCGCCGACGACGTGGAAGCCGGCATCGTCGCGCTCTGGCGCTCCTACGGCGCGGCGCGGCAGCAGGCGCTCCGGGACAGACTGGTCCTGCACTACGCGCCCCTCGTGAAGTACGTCGCCGGCCGGGTCGGCACCGGACTGCCAGCCCACGTCGACGTCGCCGACCTGGTGCAGTCCGGGATTTTCGGCCTGGTCGACGCCATCGAGAAGTTCGAACCCGAACGTGGCCTGAAGTTCGAGACCTACGCGATGCAACGCATCCGGGGTGCCATCCTGGACGACCTGCGCGCCCAGGACTGGGTGCCCCGGTCGGTCCGCAGCAGGGCGAGGGACCTGGAACGAGCACAGGAACGCCTGGAGGCCCGGTTGCAACGCACCGCCTCCGACGGCGAACTGGCCCATGAGCTGGGCATCGGCGTCTCCGAGTTGCGGGACCTCTTCGCGCAGGTCCAGCTCACCAGCGTCGTCGCCCTCGACGAACTCATCGCCGCCGGGCGGGGGAGTGCCTCCCTTGCCGAGACCCTCCCCGACGAACGCGCCGAGGACCCGGTCGCGAACCTGATCGACGGGGACAGCCGCCGCCAGCTCGCGTCGGCCATCGCGCAGCTCACCGAGCGGGACCGGATTGTGGTCACCCTGTACTACTTCGAGAACCTCACCCTCGCCGAGATCGGACGGGTCCTGGGTGTCACCGAGTCCCGGGTCTGCCAACTGCACACCCGGGCCGTGCTGCGGCTGCGCACGAGGTTGACCGGCCAGTCCTGACCCCACTGTCGGGTGGGCGGTCCCGACCGGGCCGCCCACCACGGTCGGGGAGGACGCCTCCCAGGGCAGCAGCCGGGCACGTCGGCCGGGCAACAGGGTGAGCGGGTCGAGGTACTCCCCGTCGACGAGCGCTCCCCAGTGCAGGCAGGCCGCCGAGCAACCGGGGTGGGCGCCGTCGAGCCAGCCCAGCAGCGCGCCGCCCACGACGGGCTGTCCCACCCGGACGGCCGCGCGCACCGGTTCGTAGGTGGTGCGGAACCCACCGGCGTGGTCGACGGAGACCACGGGGCGGCCACCTACCGGGCCCGCGAAGAGCACCACACCGTCGGCGGCGGCCAGCACCGGTCCACCGGGGGGAGCGGCGAGGTCGACCCCTCGGTGGCCTGGCCCGTAGGGGGTCAGCGGCCTGCTGAACAGGCGGACCACCTCGGCTCCACCGACAGGCGAGTGGGTCACCCCCGGCGGGGTGATGCTCGCCCGGTCGGGCGGAGGGCCCGGTGCCCGGTGGGGGCCGGAGCCGGGCGACGCCGGTGTGGGTGGCCGCTCCCACCGCCACCCTGCCGGGGACGCCGTCGCGGGCTCCGCGGCCCAGCCGCGCGGCGTGGGCGTGGGCACCGACGCGGACACCGCCAGCGCGGGGACGGTGAGCAGGGCCAGGGCGCGGGTGAGGCCGGTGGGCCGACGGGTGCGGGTCATGTCCGGATCGTGCGCCGCCGGTGCCCCGGGCGACCAGCCACGCACCCGCGGGGTGTGGACAACTCGGCGCTGGGGATCGCCGAGGTTCCCAGCGCATCCCAGCCACCGGGGATCTTGCCGCAGGTCGTACACTGAGTGGTGCGGGCTGACACTGTGCGGTCCGACTTCGCGTGATCGCGCGCGTCGGCCGGGTTCTCCGGGCGGCACGGCATCCGGTGGTCCCGACCTCACCCTACGGGGTGGTCGGGCTCCGATGGCGGCGCGACACCAGGACAGCGGGCCAACCACCCGCTGTGACAACCACCAGCGCGCCTCGGCGCGCCCGAGAACACGAGGTGCTAACCGGCCATGGCCGTCGTCACCATGAAGCAGCTGCTCGACAGCGGCGTGCACTTCGGGCACCAGACCCGTCGTTGGAACCCGAAGATGAAGCGCTACATCTTCACCGAGCGCAACGGCATCTACATCATCGACCTCCAGCAGACGCTGACCTACATCGACCGGGCCTTCGAGTTCATCAGGGAGACCGTCGCCCACGGCGGCACCATCCTGTTCGTCGGCACGAAGAAGCAGGCGCAGGAGGCCATCTCCGAGCAGGCCCTCCGCGTGGGGATGCCCTACGTCAACCAGCGCTGGCTGGGCGGCATGCTCACCAACTTCTCCACGGTGCACAAGCGCCTCCAGCGGCTCAAGGAGCTGGAGTCCATGGAGCAGACCGGGGGCTTCGAGGGTCGCACCAAGAAGGAGATCCTCATGCTGACCCGGGAGAAGGACAAGCTGGAGCGGACCCTCGGCGGTATCCGCGACATGGCCAAGGTCCCGAGCGCGGTGTGGATCGTCGACACCAAGAAGGAGCACATCGCCGTCGGTGAGGCCCGGAAGCTGGGCATCCCGGTGGTGGCGGTGCTCGACACCAACTGCGACCCCGACGAGGTCGACTACCCGATCCCGGGCAACGACGACGCCATCCGGTCCGCGGCGCTGCTGACCAGGGTCGTGGCCGACGGTGTCGCGCAGGGCCTGATGGCCCGCTCCGGCCGGGGCAACGCCCCGGAGGGCCAGGAGAAGCCGGAGCCGGGCGTCGCCAACGACGAGCCGCTGGCCGAGTGGGAGCAGGAGCTGCTCGCCGGTGCCGCCAGCGAGGGCGAGAAGCAGGGCAGCGAGCAGCCCGCCCAGGCCTGATCGCAGCCGGACCGCCGACGCCGCCCGGGCGGCGTCACGCGTCGGACGAGAGCGGTTCCACCGCTCCGCCACCGTCAGCACGGGGTCACCAGACACTCACCCGCGCCGCGCGGTGCCGGCCAGCGGGTACGCAACGACGAGAAGGACTGACGACGCACATGGCGAACTACACCGCCGCCGACGTCAAGCGGCTTCGTGAGCTCACCGGCTCCGGCATGATGGACTGCAAGAAGGCGCTGGAGGAGTCCGCCGGCGACCTGGAGAAGGCCGTCGAGCTGCTCCGCATCAAGGGCGCCAAGGACGTGGGCAAGCGTGCCGAGCGCACCACCGCGAACGGCCTGGTCGCCGCCGACGGCGGCGTGCTGGTCGAGCTGAACTCCGAGACGGACTTCGTCGCGAAGAACGCCGAGTTCCAGGAGCTGGCCGCGAAGGTCGTCCAGGCCGCGAAGGAGACCCGGCCGGCCGACGTCGCCGCGCTGAACGCCGCCTCCGTGGGCGACAAGACCGTCGCCGACGCCGTGCGGGAGCTCTCCGCCAAGATCGGCGAGAAGCTCGAGGTCTCCAAGGTCGCGGTGTTCGACGGCCAGGTGGCCGTCTACCTGCACCGTCGGGCCGCCGACCTGCCGCCGGCCGTGGGTGTGCTGGTCGAGTACACCGGGTCGAACGAGGACGCGGCCAAGGCGGCGGCCATGCAGGTCGCGGCGATGCGCGCCAAGTACCTCACCAGGGACGAGGTGCCCGCCGACATCGTCGCCAACGAGCGGCGCATCGCCGAGGAGACCGCCCGCGAGGAGGGCAAGCCGGAGCAGGCGCTGCCCAAGATCATCGAGGGTCGGGTCAACGGCTTCTACAAGGACGTCGTCCTGCTGGAGCAGTCCTCGGTCCAGGAGTCCAAGAAGACGGTGAAGGCGGTGCTCGACGAGGCCGGCGTGACGATCACCCGTTTCGCCCGCTTCGAGGTCGGCGCTTCCTGACCCGCACCACCCTGGGCACGGAACTCCGGAGAACCCGGGGTTCCGTGCTCAGCTCTGCCAGGCCCTGGTAACACCCCGTCCAGCCCGTGAGGAGAGTAGGTCCGGTGTCCGACCCGCAGATCGACGACGACCACCCCGGTTACCGCCGCGTGATGCTCAAGCTCGGCGGTGAGATGTTCGGCGGTGGCGCGGTGGGCGTCGACCCCGACGTGGTCCAGACGGTGGCACGGCAGATCACCGAGGTCGTCCGCACCGGTGTCCAGGTCAGCGTCGTGATCGGCGGCGGCAACTTCTTCCGGGGCGCGGAGCTCCAGCAGCGGGGGATGGACCGCGACCGGGCCGACTACATGGCGATGCTGGGCACCGTGATGAACTGCCTCGCCCTCCAGGACTTCCTGGAGAAGCAGGGCATCGACACGCGGGTGCAGACGGCCATCACCATGGGGCAGGTCGCCGAGGCCTACATCCCCCGTCGCGCCGAGCGCCACCTGGAGAAGGGCCGGGTGGTGATCTTCGCCGCCGGCGTCGGGATGCCGTACTTCTCCACCGACACCGCCGCCGCCCAGCGCGCGTTGGAGATCGGCTGCGAGGTGGTGCTGATGGCCAAGGCCGTCGACGGCGTCTACACGGCGGACCCGAAGAAGGACCCGACCGCCACCATGTACCACCACATCACCCACCGTGAGGTGCTGGAGCGTGGTCTGAAGGTCGCGGACGCCACCGCGTTCAGCCTGTGCATGGACAACAACATGCCGATCCTGGTGTTCAACCTCCTCACGGAGGGCAACATCGCCAGGGCAGTGCGTGGTGAGAAGATCGGCACGCTGGTCTCCACCCCCTGACGAGCGCGTCCCCTCGGGGGCGTGCTGAGATCTACGAAGAGGCTGTCCCCGAGCCCTGTGCGGTCGGGCAGTGGTTGTGAGACAGGGCTCTGACCAGCATCAGCCAACCGGCGGCAAGCGAAGGAGCAGTCGTGATCGACGAGGCCCTCCTCGATGGCGAGGAGAAGATGGAGAAGGCGGTGTCCGTCGCCAAGGACGAGCTCGCCACCATTCGCACGGGTCGCGCGACCCCGGTGATGTTCAACGGCATCAGCGTCGACTACTACGGTGCGATGACGCCGATCAACCAGGTCGCCAGCATCAGCATCCCCGAGGCGCGTCTCGCGGTGATCAAGCCCTACGACCCCAGTCAGCTGCGCGTCGTGGAGAAGGCCATCCGGGACTCCGACCTGGGCGTGAACCCCAGCAACGACGGCACCATCATCCGCGTGGTCATCCCCCAGCTCTCCGAGGAGCGCCGGCGGGACCTGGTGAAGGTCGCCAAGCAGAAGGGTGAGGACGCCCGCGTCACCATCCGCAACATCCGGCGGAAGGTCAAGGACGAGATCGACCGGATCGTCAAGGACGGCGAGGCCGGCGAGGACGAGGGCTCCCGCGCGGAGAAGGAACTCCAGAACCTGACCGACAAGTACGTCGCCAGCGTGGATGACCTCGTCAAGCACAAGGAAACCGAGCTGCTGGAGGTATAGGGCTCTCCATGATGGCGGCCGGTGACCACGACGCACCTGGTGTTGACGGGGAAACCGGTCACCACCAGCACACATCCACCCCTCCGGGAACGGCGGTGACCGGGGGGACCGCCTCCCGCGCGGGGAGGAACCTCCCGGCCGCCATCGCGGTCGGGTTGGGACTCGGGGCGTTGCTGCTGGCCGCCCTGCTCTTCTGGCGGCACCTGTTCGTGGCCATCGTGGCCGCGGCGGTGGCCGTCTCCACGATGGAGCTGCACCGGACCCTGGGTCGCGCGGCCGGGGTCCGGCTGGCCCTGGCCCCGCTGCTGGTGGGTGGCCAGGCGATGATCTGGCTCTCCTGGCCGTTCGGCACGGTCGGGGTGCTTGCCTCCTTCGCCTTGACGGTCGTCGCGTGCCTGCTCTGGCGGTTCCGGGGCGGCGCCGACGGGTACCTCCGGGACACCTCGGCGTCGGTGTTCGTGGCCGCCTACGTCCCGCTCTTCGCCTCCTTCGCGGCGTTGCTGGTGCTCTCGCCGGACGGCGCGGCCCGCACCATCGCGTTCCTGCTCGCCGTCGTGTGCTCGGACACCGGTGGGTACGTCGCGGGCGTCCTCTTCGGCCGCCACCCGATGGCCCCGTCGATCAGCCCGAAGAAGTCCTGGGAGGGTTTCGCCGGCTCCCTGCTGGCCGGGGTGGCCGCCGGCGTGGGCAGCTTCGTGTTCCTGCTGGACGGCGCTTGGTGGCAGGGGGCGATCTTCGGGGCGGCCCTCGTGGTGACCGCGACCACGGGTGACCTGATCGAATCACTGGTCAAACGGGACGTCGGGGTCAAGGACATGGGCTCCCTGCTCCCCGGGCACGGGGGGATCATGGACCGCATGGACTCCCTGCTGCCCTCCGCTGTCGTCTCCTGGCTGTTGCTCACCGTCTTCCTGCCGCTCGCGTGACCGGTCCCGGGCGGCGGCTGCCGGCCCTGTTCCAGGCGGTCACGGGCCTGGCGGGCCGGCGGGAACGGCGGGGAGGCGGTGTCCTGCCCAGCCCCAACATCTGGAACTGGCCGGATCTCTACGAGGTGGAGAACAGGGCGCAGGACCCCGACGGAGTCCTGTGGGATGCTCTGCGCGCCGCCAGGGACTGGTCGGGCGCGGACGTGGTGGACGTGGGTTGCGGGGCCGGGTTCCACCTCCCGGTGTTCGCCCGCTCGGCCGCCCGGGTGGTGGGGGTCGAACCGCACCCCCCGTTGGCCGCCGCGGCCAGGCAGCGGGTGCGCGACCTCCCCGCGGTGACCGTGCACGAGGCCGGTGCCCAGCGGCTGCCGCTGCCCGACGCGGCCGTCGACCTGGTGCACGCGAGGACCGCCTACTTCTTCGGGCCGGGTTGCGAGCCCGGTCTGGTCGAGGCCGACCGGGTGCTCCGGCCCGGCGGAACCCTGGCCGTCGTCGATCTGGACGCCACCCGGCACTCCTACGGCCGGTGGATGCGCGCGGACCTGCCCCGCTACGACCCGCTCGCGGCCGAACGGTTCTTCGTGGAGCGCGGCTTCTCCTGCCAGCGGTTCGACGTGGACTGGCGCTTCGACGATCGGCGGAGCCTGGAGTCGGTGCTGGGCATCGAGTTCTCCCCCGAGATCGCGGCGCGGGCCGCCGCGGAGGTGCCGGGACTGTCGTTCCGCGTCGGGTACCGGGTGCACGTGCGGCACAAGCCCAGGGGCCCGGTGCTGCCGAACGGGGCCACCGCCCGGGACGACCCGCGCTGAGCTCAGGCCCCCGGGTGGCCGTCCTCCCGGTCAGGGCGAGGTGACCAGCCGCAGGTGGGGCCGTGGGTCGGGGATCCCCAGCAGCCGCCGGATGATCGCTGGGGTGACCTCGATCCGCGCGGCCAGCTCCGCCAGCCCCACCCCCTGGTCCGCCGCCATCTCGGTGGCCGTCCGGAGCAGTGTCGGCTCCTCCCCGGGGAAGACCTCGCTGACCGGTTCGTCGGTGCGGAGGCCGAGACGGGACAGCTCGACCATCACCTCGCGGTAGGTCGTGTCGGAGTAGAAACCCAGGGTGCGCCCCCGCACGGCGAGTGCCGCCATCGACACCCCGTACCGGTGGCCGAGGTCGCGGAGCGACGCTGGTTCCGGTTCCACCGGCAGGAGGTCACCGATCTCCGTCGCCGGCATCAACAACTCCGCGGCGAAGGCGTTCGCCTCCGCCTCGTGCCGGGGGTTGCCGGGTGCCGGTTCGGGGTGCAGCAGCAGGTGGCCCAGTTCGTGCGCCACGGAGAACCGCTGGCGCAGCGGGTTCCCCCGATCGGTGAGCGCGATGATCGGGCGTCCACCCTTCGCCGAGGAGAACGCGTCGATGTTCTTGTTGTCGGGAATGACCAGCCGGGCGACGGCGACGCCCCGGGCCTCCAGGGTGCGCACCAGGTGCGGGACGGGCCCCGAGGGGACGTCCCAGCCTCGGCGCACCGCCCGGGCGGCCCGGGCCGGGTCACTCCCGGTGGCGGCCGGCGCCAGGTCCACCGCCGGCAGTTCGATGAGGTCCTCCAACCTGGACAGGACCTCCCACAGCAGTTCCACCTGCGCGAGGGCCTGGAGGCGCTGGGTGGCCGTGGTGGCCCGCAACGAGCGGAAGTGCGCGTTGGTGGTGTCCAGCCTCAACTGGGGACGACCGGCCGCGAAGAACCCGACGGGCAGCTCCATCACCTGGGCGCAGCGGGAGAGCACGGTCACGTCGGGTCGTGACTGGCCGAGTTCGAACCGGGAGAGCAGCGCGGCCGGCCGGCCTATCCACTCCGCCAGCTCGCGCTTGCTCAACCCGAGAAGCCGCCTGGCCATCGTCAACCTGGCCGGGTCGAAAGCCCGCGCGGCCGCGAACGCACCCGTGGTCACTGCGATCTCCTGGTTCGTCGGCCTGCCACTGCCGTGGTCGGTACCTGGTCGGCGCGCGAGCGCCCCGCGAGGGGTGACGCCGCCGACGGGCACCTGAGAATCTTGCCGACAGACATTCTTTCCCCACCGGCCGGGTGGGGCCACCGGAGATCACCCGGGGTGGTCAGGCACCGGAGGTGCCCTCCTGGGGGCGCGCCCGGTGCCGCAGGGGCAGTTCGGGCAGGTCGTGCGGATTCCAACCGGTGGTCCCGGTGGGTGCCGGCCGCGCGGTCAGCGGGCCCCCGAGGCCGGCCGTCCGCGCGTGGCCCCTGGTGAACGACGTCAGCGGCCACAGCCAACTCCACCGGATCCGGTAGTCGCGGTCCGCGCTGCCCTGGCCGACCCACGCGCCGGACAGCCCCGCCGCCTCGCTGCCGGTCCACGGGAGGAACAGGAGATCGCGGCCGCCGGTGATCGCGTGGTTGGCGGGGAACAGCCCCGGCGGTTCCTCCGGCGGCCGCACGAGCCGACGTTGGAGTTCGGTGTCGTCGAGGACCGAGGTCAGCGGCGAACCGGTCTTCGCCCGGTACTGGTAGAGGGCGCAGTTCCCGATGCCGATCGTCATGGACTGGAAAGCGGGGTTGACACGGGCGTCGGGCAGCCCGCTCGCGGTGGCGAGCAGGTACTGGTACCGGTCGGTGCCGAAGCTCCAGCCGTTGGCCCACGAGCCCCGCGCGGACCTGCGCCGGACGCGTTGGAGCTCGGCCGCGGCGCTGTGCGCCAGGGCCAACCAGTCCAGCAGGTGGCCTGCCACCGCCGCGGACCGCGTCTCGCCGACGAGGCGGTCGAAGTGGGGGTCACCGATCGGTTCGAACCTGTCGTCCTCGGGAAGCACCGCTGCTCCTCACCGCCCAGGGGCTGTTCGTCCTGCGGTGACCTTGCTACCGCCAGGCACCGACAGTGACGCGTACCGACCGCGCGGCCGACGGGGACACCGGTGGTGACGCCGAGGGCGCCAACAGGAGGGACGCCGCACGGGGCCGGCAGGAGGCCGTGGGACACTGGTCGCGCCATGACTGCACTTCCCCTGGTGTTCGACGCCCCCCGCCGTGGGCTTCCGCCCCGCCACCTCGCCGACCTCTCCCCTGAGGATCGCCGGTCGGCGGTCGCCGAGCTCGGCGAGAAGGCGTTCCGCGCCACACAGCTGTCCCACCACTACTTCGGCCGGCTCAGCGTGGATCCCGAGTCGATGACCGACATCCCCTCGGCGACGAGGGACCGGCTCGTGGAATCCCTCCTGCCGACGCTGTTCACGCAGGTCAGGGAGGTGACCACCGACAACGGCACGACGAGGAAGACCTTGTGGCGGGCGCACGACGGCACCCTCGTGGAGAGCGTGCTGATGCGCTACGACGACCGGGCCACCGTCTGCGTGTCCAGCCAGGCCGGGTGCGGGATGGCCTGCCCGTTCTGCGCCACCGGCCAGGGTGGGCTCCAGCGGAACATGTCCACGGCCGAGATCGTCGACCAGGTGCGGTCGGCCGCCGCCGCCATGCGCGACGGCCTGCTCCCCGGCGGAGCGGGCCGGTTGTCCAACGTCGTGTTCATGGGCATGGGCGAGCCGTTGGCGAACTACAAGCGGGTGGTGGCCGCCGTCCGCCGGCTCTGCGAGCCGGCGCCCGCCGGTCTCGGGCTCTCGCAGCGTTCGATCACCGTGTCGACGGTCGGGCTGGCTCCCGCCATCCGGAAGCTGGCGGACGAGGACCTCCAGGTCACGCTCGCGGTGTCCCTGCACACCCCGGACGACGAGCTGCGGGACACCCTCGTGCCGGTCAACACGCGCTGGAGCGTGGACGAGGTGCTGCGGGCGGCCCGGTACTACGCCGACCGGACCGGTCGCCGCGTGTCGATCGAGTACGCGCTCATCCGGGACGTGAACGACCACCCGTGGCGGGCCGACCTGCTGGGCAGGCTGTTGCGCCAGCACCTGGGCCATCTGGCCCACGTCAACCTGATCCCCCTGAACCCGACGCCGGGCAGCGAGTGGGACGCCAGCCCCAAACCGGTGGAGCGCGAGTTCGTCCGGCGGGTGCGCGAGGCCGGGGTGAGCTGCACGGTGCGCGACACCAGGGGGCAGGAGATCGCCGCCGCCTGCGGCCAACTCGCGGCCCAGGAGTAGCCACCCCACCCACCGGTGAGGCGAGGCGATCCGCCCGCCGGGCGCGAGCCGTGGCCACAGGGGTGAGGGGCGCCGCCCTCCGGGTGCGCCCGCGCCGCGATCGCCGGGCGTGGGCGCCAGCCCACCCCGTCGGCCGTCGTGGATGGTGGTCGGGCGGGCCAGGCCCTCCCCGGCATCGGTTGTCTCCGCTCGGCCCGAGGGCGGGACCGGGCCGGAGGACCCGGCCGCCGCGCCCCCACCCCGTCCGGGGCGCGGACACGGCCATGACCTGCCGCACGACGCGGGCGCCGCGCGAACGAGGCTTCTCCGCGCGCGGTACCCCGGAGGGACCCCTGGGGACACCCGCCGGTCATGCCGGATGGCACCAGGCCCTGATCCGCCGGCGGCTCGGGCTCAGTCCACCTCGTGCAGGAGACCGGTGTCCACGTCGACGACGAAGCCTCGGATCGAGTGGGCGTGCCGGATGAAGGGGCTGCGCTTGATGCGTTCCTTGCTCTCGTGCACGTCGACCGACTCGTCCTCGAAGCACTCCACCGACCATTCGGGGGTGACGCCGACCTCCTGCCGCATCTGGGCCTTGAACTCGGCGTCGGTGAAGGTCCGCAGCCCGCAGCGGGTGTGGTGCAGCAGGATGATGTGCTCGGTGCCCAGCCGCCACTGGCTGATCGCGAGGGACCGGATCACGTCGTCGGTGATGACGCCCCCGGCGTTGCGGATGATGTGCGCCTCGCCGACGCGCAGCCCGAGCAGTTGGAAGACGTCCATCCGCGAGTCCATGCACGCCACCACCGCCAACTTGCTGGCGGGTTCGGTGGGCAGGTCGGCGCACGAGATGGGGTGAGCGGCGTTGTGGTGCACCAGCCGCTGCGTGATGGACATGGACATGGGAAACCCCCGGCCTGGTGTCTGCTCGACCGTCGGAACGGCCGGCGCGATGTCGGGAAGACCGGCGTCCGCGATAATCACCGGTGACAGGTCTGGCGCGGCGCCGCCCGGTACCGGGGTGCCGCACTGGAGGCAGTGAATCGGGTGTCACCGCGTTGAGGCAAGGAACATCACTGGGAAGTGTGACAACGGTGCGTGGGTGTGACAGGGAGATGGACCCCGGGGCGAACCCCGGGGACCCCTCAGTTACGCCACGGTGTCCGGCGGCGCGTCTGGTCCCAGATCAGGAACCCGATCATGCCGAGCCCGATCCCGATCAGCCAGATGGTCTCGACGTGACCTTCGTGGTTGCCGATCAGCATCAGGAACATGATGGCCGCGACGGCCCAGCCGGCGACGCGGCGGCCGCGCGGCCACTCGCCGTGCCAGCCCCACTCCGCCGACGGCTCGTCCCGGGGATCCACCACGTCACCGCCGGAATACCTGTCCACAGCGGCGTTGGTCCTCGACGGCTGCTCAGCGGACACGATCCCTCCAGCACGGGCTCATCACGTAGCTTGCCGACCTATCCTCGCACACGGTCCCCCGTCGGTGCCCTGGCGGCCGCGCCGGACCACCGGGTGCGCGAAGCGGCACCCTCGCCCGTCGACCTCGGTCGTGGGGGCCGCACCCGGGCGGCACCGCCCTCCCGGCGCCGCGCCCCGGCGACTCGGGTCCGGCCACCCGTGCGGGGGATCACCGCCTAGGCTGTCCGCCGCGGCGCGGCCCGCGTCAACCCCATCCACCCCAGACGCCCTCCCGGAGGTGAGCCATGTCCGAGGACCCGCGAGAGACACCGGCACTCGACCACCGCGTCCCCGACGCCTCGGGCCCGCCCGCCGTCGAGCTGCGCGGGGTGACCAGGACCTACACCGACCAGGTCGCCGTCCGTGACCTGAGCCTGCGGGTGGGGGAGGGCGAGTTCTTCTCCGTGCTCGGCCCGTCCGGGAGCGGGAAGACGACGCTGCTGCGGATGGTCGCCGGGTTCGAGGACCCCGACGGGGGAGCGATCCTGCTGGGGGGCCGCGACGTGGTGGGGGTACCCGCCCACCGGCGGGACGTCAACACCGTCTTCCAGTCCTACGCGCTCTTCCCCCACCTCTCGGTCTGGGACAACGTGGCCTACGGGCTGCGCCGGCTGGGACTGCGCCGCGCGGAGCTGCGCGCCAGGGTCGGCGACTACCTGGACCTCGTCCAGCTCGCCGGCTACGGGCGCCGTCGGCCGCACCAGCTCTCCGGCGGGCAGCAACAGCGGGTGGCCATCGCCAGGGCGCTCGCCCGCCGCCCCCGCGTCCTGCTGTTGGACGAGCCCCTGGCGGCGCTCGACGCCCAGCTCCGGGCGCAGCTGCGGGTCGAGCTGACCAGGATCCAGCGCGAGGTCGGCACCACCTTCCTCTACGTCACCCACGACCAGGAGGAGGCGCTGGTGCTCTCGCACCGGCTCGCGGTCCTGCGGGCCGGCCGGGTCGAACAGGTGGGCACTCCCGCCGACGTCTACGAACGGCCGGTGAGCCGGTTCGTCGCCGAGTTCATCCGCTCCTCCACCACGGGTGGCTCGAACGTGCTGGAGGGGACCGTGCGGACCGTGACCGGCGCCGGGAACGCGGCGCTGGTGGAGGTGTCGGTGGGGGAGGGGGCCGTCCTGGCCGAACTCCCACCGGGCCGGGCGCTGCGACGGGGACAACCGGTGGCGGTGGCGGTGCGCCCGGAGAAGGCCCGGCTCTACTCCGCGGAGGACGACGGACCACCACCAGGGTGGTCCCGGGTGCCCGTCCGGCCGCGAGACACCGTGTATACCGGCGCCGCCACCGAACACCTCGTCGAGGTCGTGGGGGACCCCGGAGCCACGCCGCTGACCGTGTTCACCCAGAACACCCGGCGGGCGGGCGAGACCGGGCCCGGTGGCGGTCCGGTGCTGGTGGGCTGGGAACCGCGGTTCAGCGTCCTGCTGGCCGATGAGCCGGGCCGTGGGGACGGCGGCGCGGAGCCGGGCGGACGCGCTCGTCCCACGGCGGCGGACGGCGATCCCACCCCGGGTTCGGCACCGACTCCGGTCGGCGCCACCTCCCGGGCGGACGTCTCGTAGCGCCCGCTGAGCACACCAGCCGGACACACCCCGGACGGCCCGCCAGCTGGCGCTGCCCGGGGGAGGGGAGGACCACTCGCACATGGCGGACAGGGACGCGGTACGGATCGCGCGGTTGTGGGACGGTCGGGAGCGGCCGGTCACCCGACGCGCGATGCTCCGGTCGACCGCATTCTTCGCGTTGGCGGCGCACGGGGCCGCGGGCTGCGCGATCTCGGAGCCGGTCGAGCCACGTCGTACCGACCCGAGGGCGACCCGGGCCGTCAACGAGGTCGAGGAACCGGTCCTGAACTTCTTCAACTGGACCGACTACGTCGACGAGGACACCATCCCGGGCTTCGAGGACGAGACCGGCATCTCCGTCACCTACGACAACTTCAGCTCCAACGACGAGCTGGAGGCGAAACTCGCCGCCGGAGGCAGCGGCTACGACCTGATCGTGCCCAGCGACAACTTCCTGCGGCGGTTCCTCCGCTCCGACCTCCTGAGCCCGCTCGACCACGACCTGATCCCCAACCTGGACAACCTGGACCGGCGGTTCCGGGAGGCGGAGTACGACCCGGACAACCGGTACTCGGTGCCCTGGGCCTGGGGCACCACCGGGCTCGCCTTCTCGCGGCAGGCCCTCGGCGGGGCCGACGTCACCTCGCTGGACGCGTTCCGGCTGGCCGCCGCCCGGGGGCGGAGCGCCCTGCTCGACGAGGCCAGGGACGCGATGGCCCTGGGGCTCCTGGGCGCGGGTCACGACCCCAACACGACCGACCCCGGGGAGTTGGAGGACGCCGTCGAGTACCTGCTCGACCTGAAGGGCGTGCTCGGTCAGATCACCTCGGACGTGATCGAACCGCTCGCCTCCGGGCAGGCCCCTCTCGCGCAGGCGTGGTCGGGGGACGTGTTCCAGGCGATGGAGACGAACCCGGAACTGGACTTCGTCATCCCCGAGGAGGGCGGCCTGTCCTGGGTGGATCTCCTCTGCGTCCCCCGGTCGGCGCCGCACGCCGCCAACGCCCACCGCTTCATCGACCACATCCTGCGGCCCGAGGTCGGGGGGAGGTTGGCCAACGCCATCCAGTACGGCAGTCCGAACGCGGCCGCGCGCCCTTTCGTGGACGCCGAACTCCTCGCCGACGAGCGCATCTACCCCTCCCCGGAGGCGCTAGCCCGGGTCCCCTTCACCCGCGATCTGGGACCGGAGGTCGAGGGCCGGTACGCGGACGCCTGGACGAGGGTGAAGACGGGCTGATGGATGGCGTGACGAGAGCCTCGGGCGGGCCGCGGCGCCCCCGGCCCGAGCCCACCAGCGGCGCCGGCCGCCCCGGTGGCGCGGCCCGACCAGCCCGCTCCCGGGGGCGAGGACGTGCCCGCGCGCACGGCCGTTCCCTGGCCGGCTGGGCGGCCCTCGCCCCGGCGGGCCTGTGGCTGGGCGCGTTCTTCGTGGTCCCGGTGGCCCTGGTCGCGCAGTACAGCTTCGCGACCAGGGACCTCGGCATCGCCCGCGTCGTGCTCCCCTGGACGCTCGACGCCTACCGGCTCGCCGTCGACCCCGCTGTGCTGCCGATCTTCTGGCGCACCGCCGCCTACTCCCTGTCCGCCACGCTGGCGTGCCTGGTGATCGGGTTGCCGCTGGCCTGGTTCGTCGCCCGGCACGCAGGGAGGTGGCGGCTCGTGCTGTTGGGAGCGGTGCTCGTGCCGTTCTGGGCGAGCCACCTCGCGCGGATCTACGCCTGGAAGGCGCTGTTGGCCGAGGACGGGCCGGTGAACCGGGTGCTGGGCCTGGTGGGGCTGGACCGGCCGGGTGGGCTGTTGCTGACCGACGTCGCCGTCGTGGTGGGGCTGACCTACGGCTACCTGCCCTTCATGGTGCTCCCGCTGTACGTCGTCTGCCGGCGTTTCGACCCGAGGCTGCTGGAGGCGTCCCAGGACCTGGGGCACGGGCGGCTCGGCACCTTCGTCCGGGTGGTGCTGCCCGGGCTGGCCCCGGGGGTGGTGGCCGGGTCGTTGTTGGTGCTGGTGCCCTCGGTGGGCGACTTCGTGACACCGGCCCTGCTGGGCGGGGTCAACCAGTTGACGTTCGGCAGTGTCATCGACGACCAGTTCCGGGGTGGGAACAACTGGCCGCTCGGCTCGGCGCTGGCGGTGCTGCTCCTCGCCGCGGTGGCGGTGTTGTGGGTGGCGCGCGGCCGACGGGCGCGGGAGGTGCTGTGACCGTGGAACACGCGGGACGGGGACGTCGTGCGGCCCGGGGTCGCCGGCCCTGGGTGCTGCTGGCCACCGTGGTGGGCGCCTACGCCTTCCTGTACGCGCCGATCCTGTGGCTGGCCCTGCTGTCGTTCAACGACTCCCGTTCGGTCAGCACGTTCACCGGGTTCTCGCTGCGCTGGTACGCGGAGCTGCTCACCGACGGGCAGGTGCTGGACGCCCTGTGGTTGACCGTCCGGTTGGCGGCCAGCACGGCCGTGGTGGCCGCGGTGTTGGGCACGCTGGCGGCCTGGGCCCTGCGTCGGCCGTTCCGAGGGCGGGGGCTGTGGTCGACGGTGCTCGCGATGCCCCTGGTGGTCCCCGAGGTGGTGCTCGGGGTGAGCCTGCTGGCCTTCTGCGTGAAGCTGGCGGGCATCCCGCTGGGGTTCGGCGCCCTGTTGGCCGCGCACGTCACGTTCTCCCTGAGTTTCGTCGTCATCGTGGTGCGGGCCAGGCTCGCCGGGCTCGATCCGAGGCTGGAGGAGGCGGCGGCCGACCTCGGCGCCGGCCCCCTGACCCGGTGGCGCACCGTGACGCTGCCGGTGCTGTGGCCGGCGATCGGGGCGGGGGCCGCGTTCGCCTTCGTGCTCTCCTTCGACGACGTGGTGACCTCGAGCTACCTCTCGGGGGTGGGAGGTACCCCGTTGCCGGTCCTGGTCTACGGGCAGGCCAGTCGGCGCGGTGTCTCACCGGAGATCGTCGCGCTGTCCACCAGCATGGTGGTGCTGAGCACCGTGCTGCTCGTGCTGGCCGTCCTGGTCGTCGCACGGCGAGCGCGCCACCTCGACCGGTGACGCGCTCGCCGCTGGTACTCGGGTCAGGCGTGTGCTCGCCGCCCCGTGACCAGGCGGTAGATGGCGAGCAGGATGATCGAACCGAGAATCGCCAACAGCCATGTCCGGATCTCGAAGAACGAGCCGAGGTCGGTGTCGAAGATCGCGCGGCCGATGAAGCCGCCCACGAAGGCCCCGATCACGCCGAGTACGAGAGTGATGATGATCCCGCCAGGATCGCGGCCGGGCATGATGGCCTTGGCGATGAGGCCGGCCAGCAGACCGAGGACGATCCAACCGAGAATACCCATCGAAACCTCCTAGGAGTTCGCCGCCACCGGGCGGCGTGGGGCTGGGAGAAACCCCAGCTCCACGGTCCTTCGGCGGTGTTCATGACCTGACTCTGGAATAACCACGTCCGGTGAGGGCCATGCGTCCGTTATCGTTCCGTTATCAACGGCGGGTGGTGGCCGGCCGCTCCCCCGTCGCCCTCCGTGGCCGTCGACCCCGCCCCGGGGCGGGCGGCCGAGCCGGCTCCGCGACAATGTCGGGCCATGAGCTCGCTGTCCCCCACCTCGACCGCCGCCGAGCCGGGTCCCCGCCCCGTGCCCGCCGAGGCCCCCTCATCGGCGCGCCGCGTCCTGCTCCTCGGATCCACCGGGTCCGTCGGAACGCAGACCCTGGACGTGGCCAGGCGGAACCCGGACGCCGTGCGCGTCGTCGGGCTCGCGGCGGGCGGTGCGAACCTGGACGCGCTGGCCGCCCAGGCCCACGACTTCCAGGTGGAGGCGATCGCCGTCCCCCGCGTCGGGGTCGAGCGAGACCTGGTCGCGGCCTGGCGCGCCGAGGCCGAGCGGCGTGGAGTCCTGGCCGGTACGGCCCCGCCTCGGGTGCACACCGGCGTCCGCGCCCTGCTGGACCTGATCGAGTCCACCCCCTCGGACATCGTGCTGAACGCCGTCACCGGCTCGCGGGGCCTGGAACCGACGCTGGCCGCCCTGGCCACCGGCGCGACGCTGGCCCTGGCCAACAAGGAGTCCCTGATCGCCGGCGGCCCGCTGGTGCTGGCGGCCGCCGCTCCCGGCCAGATCGTCCCGGTGGACTCCGAGCACTCCGCCCTGGCACAGTGCCTGCGGGGCGGCCGGGCCGACGAGGTGGACCGCCTGGTCCTCACCGCCTCCGGCGGCCCCTTCTACTCCCGGACGAGGGAGGACCTCGAGGCGGTGACCGTCGAGGAGGCCCTGGCGCACCCGACCTGGTCGATGGGCAGGGTCATCTCCGTGAACTCCGCCACGCTGGTCAACAAGGGGCTCGAGCTCATCGAGGCGCACCTGCTGTTCGGCGTCCCCTACGACCGGATCGACGTCGTCGTGCACCGCACCTCGGTCGTGCACTCGATGGTCACCTTCGTGGACGGATCGACCCTGGTCCAGGCCAGTCCGCCCGACATGCGACTGCCGATCGGCGTCGCCCTCGGCTGGCCGCGCCGCCTGCGCGACGTCTCCTCGCCGTGCCGCTTCGACACCACGACCACGTGGACCTTCGAGCCGGTGGACAACCTCAGCTTCCCCGCCGTGGAGCTGGCCAGGGCCGCCGGGCGCGCGGGCGGGTCGGTCCCTGCCGTGTACAACGCGGCCAACGAGGAGGCCGTGGAGGCCTTCCTCGAAGGTCGCACGAAATTCACACGGATCCTGGAGACTGTGGAGCGGGTGCTGGCTGAGGCCGACGAGTGGCGTCGGGACCCCTCCGGTGTCGACGACGTTCTCGCAGCCGAGGACTGGGCGCGGGCCCGGTCGCGGCGGCTGCTCGGTGTGACGGGCCACGCTGCGGGCTCGGTGGGAAAGGACTGACGCGTGGCCTTTGTGATCGGGGTCATCCTGTTCGCCATCGGCATCGGGGTGTCCATCGCGTTGCACGAACTCGGGCACCTGGCCGCCGCCAAGGCGTTCCGGATGAAGGTCACCGAGTACTTCGTCGGCATGGGGCCGAAGATCTTCTCGTTCCGGCGGGGCGAGACCGAGTACGGCCTGCGAGCCCTGCCCGTGGGCGGCTACTGCCGGATCACGGGCATGACCTCCCTCGACGAGGTCGACCCGGTGGACGCGCCCAGGGCGATGAACCGCAAGCCGGTGTGGCAGCGCGTCGTGGTGCTGTGCGCCGGCTCGGCGACCCACTTCATGCTCGCCTTCGTGATCCTGCTCACGATGGCGGTGACGATGGGCCTGCCCAACATCAGCGGCCGGGCGGTCGTCGCCGAGGCCAGTTCCTGCGTCCCGCCGGACCAGGACCTGGAGACCTACGAGTACGCCGAGTGCACGCCCGGCCAGGACCCGGCACCGGCCAGGGACGCCGGCGTGCTGCCTGGTGACGAGATCGTCGCGGTCAACGGCGAGGCGACCGGCAACTACACCGAGGTGCAGGCGGCCCTGGTCGAGCAGAGCGGGGACAGCGCGACCATCACGGTCCTGCGGGACGGCTCCGAGCAGGAGCTGACCATCCCGATCGTCCCCGTGCAACGGGTGATGGTGAACCCGGAGACCGGTGAGGCCGAGAAGGTCGAGACCAACGCGCTGGGTGTGAGCTTCCCCAACTACCTGCACTTCACGGCCGCCCAGGCGTTGCCGGGCACGCTCACCTTCACCGGTGAGATGTTCGTGCACACCTGGGAACGCCTGCTCGAACTGCCCAGCCGCGTGCCCGCCGTCATCGACGCCATCCTGGGTGCCGAGCGCGACCCCAACACCCCGGTCAGCATGGTGGGAGCGAGCATCATCGGCGGCGACGCCGTCGCCGGCGGCTACTGGGAGCTGTTCCTGTTCCTCCTGGCCACCCTCAACCTCTTCATCGGCGTGTTCAACCTGCTGCCACTGTTGCCCCTGGACGGCGGTCACGTCGCCGTCAACCTCTACGAGAAGGCGCGGGACACCATTCGGGGGTGGCGCGGCAAGGCCAAGGGGGCGCCCGTCGACTACACCAAACTGCTGCCCATCACCTATGCGGCGGTGTTCATCGGCGGTGCGTTCATGCTCCTCACCCTGACCGCGGACATCGTTAACCCGATCCGGTTGCGTTAGCCCCGCCTGGCCACGGGGCGTGCGAGCAGGGCGTTCACCTCGTGGCCACGCTCCCTCCCCCGGGGCGGCCACCCGGCGGCCCGGGTGAAGGACTGCTAGTACGCTGGTGACGGCCCGGTGGTCGGGCTGTCACCCTGTCGGCCCTTGCGCGGGCCACGACATCGGACATCTGGTCGCGGAGAGGACCGATGAGCGTCGAGCTAGGAATGCCAACCATCCCGCCGCCGGTGCTGGCGCCCCGCCGCACGACCCGCCAGCTGCGGGTGGGCGCGGTCGGCGTGGGCAGTGACCACCCCGTCTCGGTCCAGTCGATGACGACGACCGTGACGGCGGACATCAACTCGACCCTGCAACAGATCGCCGAACTCACGGCCTCGGGCTGCGACATCGTCCGGGTGGCCTGCCCCAGCCAGGACGACGCCGACGCCCTGCCGGCGATCGCGAGGAAGTCGCAGATCCCGGTCATCGCCGACATCCACTTCCAGCCCAAGTACGTGTTTGCCGCCATCGAGGCCGGCTGCGCCGCCGTCCGGGTGAACCCCGGCAACATCAAGAAGTTCGACGACAAGGTCAAGGAGATCGCCCAGGCGGCCCGGGACCACGGGACCCCGATCCGCATCGGCGTCAACGCCGGGTCGCTCGACCCCCGCCTGCTCGCCAAGCACGGCAAGGCCACCCCGGAAGCGCTGGTGGAGTCGGCGCTGTGGGAGGCCGGCCTGTTCGCCGAGCACGACTTCCACGACATCAAGATCTCGGTCAAGCACAACGACCCCGTCGTGATGGTCCGGGCCTACGAACTGCTGGCCGAGTCCTGCGACTACCCCCTGCACCTGGGCGTCACGGAGGCGGGCCCCGCCTTCCAGGGCACCATCAAGTCCGCGGTCGCCTTCGGCGCGCTGCTGCGGCAGGGCATCGGGGACACCATCCGGGTCTCGCTGTCCGCGCCGCCGGTCGAGGAGATCAAGGTCGGCACGCAGATCCTCCAGTCGCTGAACCTGCGGCCCAGGAAGCTGGAGATCGTCTCCTGCCCGTCGTGCGGCCGTGCCCAGGTCGACGTCTACAAGCTGGCCGACGAGGTCACCGCCGGTCTCGACGGCCTGGAGGTCCCGCTGCGAGTGGCGGTGATGGGCTGCGTGGTCAACGGCCCCGGTGAGGCCAGGGAAGCCGACCTCGGCGTCGCCTCGGGCAACGGCAAGGGGCAGATCTTCGTCAAGGGCAAGGTCATCAAGACCGTTCCCGAGCACAAGATCGTGGAGACCCTCATCGAGGAGGCGATGCGCATCGCCGAGGAGATGGACGGTGACCCCAGCACGCTCGTGGGCGAACCGACGGTCACCGTGAGCTGATCCCCTCGGCTCGTCGGGCGCGGTGCCCCGGGCCGCGAAGGGGCCCGTGGTCGGTCCACTCAGGTGTCGATCCCGACGCCCTCGACGCGCCTACCCACCCTTCCGGTGCTTTCTGGCACTCTGGGACCGTGCTGAAGCTCGCGGGTGCAAGGTTGCTCACGGAGCGTGAGGGTTTGGCGGTCCGATCAGCGTTGGTCGCTGATCCTGTCGTGAGCTGTATGGTCGCCGCCAGGGTGGAGAGCGTGGGCTTGGACCCCTGGCGGCTCGGCGGGGAACTGTGGGGTGTCGGGAGCCGACTCGGTGGGCTCTGCTTCTCCGGGGTGAACCTCATCCCGCTGCGGGGCGGGAGGGCCGCCAGCCGCGCCTTCGCGGAACGAGCCCTCAGCCAACCCCGGCACTGCTCGTCACTGGTCGGCCCCGCCGACCAGGTGTTGGAGATGTGGCAGCAGCTGGAACCCGGGTGGGGGCCGGCACGTGACGTGCGGCCCAACCAGCCGTTGCTGGCGATGTCCGCACCGCCCTCGGTCGCCCCGGACCCGCTGGTCCGCCAGGTGCGCCTCGACGACCTGGAGCGCTACCTGCCGGCCGCCGTCGCCATGTTCACCGAGGAGGTCGGCATCGACCCCCAGGGCGAGGACGGCGGGGCCAGCTACCGGGCGAGGGTCGCCGAACTCATCGTCAACGGCCGCGCGTTCGCCCGCTTCGAGGGAGGCGAGGTCGTCTTCAAGGCCGAGGTCGGCGCGCTCTCCGCCAGGGTCGGCCAGATCCAGGGGGTGTGGGTGCACCCGGAACACCGCAACCGGGGTCTCGCCGCCGCCGGCACCGCGGCCGTCGTCGACCGCCTCTCCGGGTGGATGGGCCGCATCGCCAGCCTCTACGTCAACGACTACAACCTCCCGGCCCGCGCGGTCTACCGGAAGGTCGGCTTCTCCGAGGTGGGCCGGTTCGCCACCGTCCTGCTGTGACCCCCTCGTGAGCGGTCCTGATCGCTCCACAGTGGCCCAAGAGTTTCCGGCCTTCGAACAGCGGAAACACGACTCGAGGCGGTCGGGCCCTGTGCCAGGGGACACGAATGTGGGCATACTCCAGTCGTGGTGGTCGTCGTTTCCTCCCGGCCGGGACGCCGAGCCGGAACCGTGCTGCTCGCTGGTGCGCTGTCCCTGACGCTCAGCGGATGTGGGGTGTTCGACTCGGGCCCCGGCCCGGAACAGGCCCTGGCGGACTTCGTGGCCGCGATGGGCGCCCGTGAGCCGGAACGGGCCGCGGCCCTGACCGACAGCCCGGACGGCGCCCTGCCCACGCTGGAGAGCGTCGACCGCGCGCTGGCACCCGAGGGAGCCAGCGCCGAGGTGATCGAGGTGCGGGAGACCGACGGGTCCACGCACGCGGATCTCGACATCACCTGGGAACTGGCGGGGGACCGCACCTGGAACTACCACGGCACGGCCCGGTTGCGCGAGATCGAGGGGGACTGGCGGCTCGAGTGGGCGCCCTCGGTCATCCACCCCGACTTCGGGGAGCAGCAGACGCTCGCCGTCCGGACCGAGGCCGCCCCGTTGCCACCCGTCCTGGACCGTGACGGGCACGTCGTCCTCGATCCCGGCGTGGTCATCTCGGTCCTGCTGGACCCGGCGGCCACCGAGGAGCAGGAGGGCGACGTCACCGAGGTCGCCACGGTGCTGGGCGACACGCTCAACCGCTTCGACGACCGCATCACCCCGGACTCGGTGCTGGAAGGGGTGTCCGACACCGAGGACGGCCACTCCTACCTGGTCGCCACCCTGCGTGAGCCCGACTACCACTCCGTCCGGTCCGACATCCACGAGCTCCCCGGAGTGCGCTTCACCAACCAACCGCGCCTGCTCCCGGTCACCCGGGACTTCGGTTCGCAGATCCTGCCGTCGCTGCGCCGCGGCGTCGAGGAGGCCAACGTCGAGCGGGCCGGGTGGCGCGTGGTCAGCCTCGACGCGACCGGCGCCGAGGTGAACACCCTGCACCACGAGCAGCCCCGCCCGGCGGAGGCCACCCGGCTCACCCTGTCCCGTGCCGCCCAGGCGGCGGCCGAGGACGCCGTCGAGCCCTTCGACGAGCAGGCCATGCTGGTGGCCGTCGAGGCGTCCACCGGTCACGTGCTCGCGGTCGCGCAGAACGCGGCGGCCGACGCCGAGGGCCCGGTCGCGCTCGTCGGCCAGTACCCGCCGGGCTCCACCTTCAAGATCGTCACCGCCGCCGCCGCGCTCGCCTCCGGGCAGGTGACCGCGGACCGGACCGTCGCCTGCCCGGCCACCACCGCCATCGACGGTCGACTCGTGCCGAACAACGACCGCTTCGACCTCGGGGACGTGCCCTTCCACACGGCCTTCGCGCGTTCCTGCAACACCACGTTCGCCACCCTCGCCTCCGACATGGAGCCGGACGAACTGGCCGAGACCGCCCGCCAGTTCGGCCTCGGGCGGGAGTTCGTCATCCCCGGTCTCGCCACCTGGACGGGGCCGGTCCCGGTCACCGACAGCTCCGCCGAGCGGGTGGAGGCCGGTTTCGGGCAGGGCACCGTCCTGGCGAGCCCCTTCGGGATGGCTCTCGTCGCCGCGACGGTCGCCGCTGGCACGACCCCCACCCCGGTCTTCCTCGCCGAGGACGACCGGGAACCCTCGGATGCGGCCGGTGCGGCGGCGGGGGGAACGAGCGCCGAGCCGGACGGCCCGTCCTCGGCGGGCCCCGTCGAGGCGCCCTCAGCCCAGGTGATCGACGCGTTGCGACCGATGATGCGGGAGGTGGTGACCGAGGGCACCGCCACCGAGCTCGCGGGGCTGCCCGAGGTGCACGGGAAGACGGGCACCGCCCAGTTCGGGGACGGCTCCCGGTCCCACGGGTGGTTCGTCGGCTACCAGGGGGACATCGCCTTCGCCGCACTCGTGGTCGACGGCGGCAGCTCGGCCCCGGCCACCAAGCTGGCGGGCGACTTCCTGGGCTCCCTCGGCTGACCCCCGGCGGGAGCGTCTCACGTCCAGCGCCGCCAGGGGGAGTGCCGGTGGTTCCTCGCCCGCTCGACCACCAGTGGAAGGGGAACGGGGGAGGAACCCGTCGACAGGCGTCCCTCCACCTCCTCGCTCAACCCCCGGCAGGTGGGGCAGAGGCTCGTGGCGTCCAGGGGATCCATCCCGGTGCCGTGGCAGTTCGGGCAACCGGACTTCAGGCCGATCAACATGGGCACTACTGTGCCGGAGCCTCGTCCGGGTAGGACCAGCGCTCCACCATCGCGGGTTGGTCACCGTCGACCCGGGGCGCGATCAGGTCGCACAGGTGGGAACCGCTCAGCCGGATCATGTCCTCGCCGCAGGCGATCAGGTCCCCCACGAGCACCGTCGCCGAGAGCAGACCCCGGTTGTAGTGCACCCGCACCCGGGTGCCAGGCGCCAGGTTCTCCGGGTCCCGCACCAGTGCCCACGCGCCGAAACGGCGCCGCCCGGATGGTTCAACCACAGTCACGGTATCCCCCTCGCCGCCGGGTTCGCGCCACCCGGCGGCGGTCCCGTAACCGGAGCAGTCGGTTGCACTCGTTGGGCAACGCCGCCATCACGTGCCGCTCGGTGATCAGGCTGTTGATGCCCTGCCAGAACCGGGCGCCGGTGACGCCGTACCGCTCGCGGGCGGCCTGCTCGAGTGAACCCGGGTACCGCCACCAGGATGTCGCGAACCGCACGGCTGCCACCTGTTCCTCAGGATCGTCAGGAGGCCAGGCGGTAGTCACGATCACCAGCCTACCCGGGAGTATGACGATCTCGGCATGCCCTGGCGGCGCGTCACCAGCGGCGGACCGGTCCCCGCCTGGCTTCGCGGGCACCTCGGTCCACACCGGCCGGAGGGGGCGGCGGCGGGGGCGGCGCGGCCAGCCAGGATGTCGCCGCCGGGTGGTGGGCCGCCCACTTCGCGAGCCCGCCCCTCCCGCTCGGTCCCGGCCTCCGCCCAGGCACCCCGGACCACGGTGACCACCGCCGGTCCACTGGCGCGGCCCGCCCTGTCGTCGCCGGTCCACTGGCGCGGCCCGCCGCGTCGTCGTCACGGGTGAGGCCCACCTCGGGCGGTGGACGCCGGCAGTCCGGCACGACCGGGGACCGCGGGACGCCGGACGGTGGACCCGGTCCACTCCCACGGACGCCGGCGTCGGGGGCGCGAAGCGCTCCGGCCGCCGTCGCACGTCGGTGGCCGGCACCGGGTCCGCACCGGGGCGACCGCGCGCTCGTCGGGTGGGAGCCGCGAGTGGCGGTCGAGGAGGAGGGCCGGCGGGCGGCCGTGGCCGACGCCTCGACGTGGGGAGCCGCCCCGACGTCCGGTCGGCCGGGGGGACCGGTCGCGGGCGAGGGGTTCGGGACGGGGGAGCTCCCGCCGGCGCGGCGGCCTCGGGGAGGGCCGGGGGAGCAGCGGTCTCCGGGCACACGGCACCGGGCTCACCACCAGCCACCCCGCCGCTCCCACCGGAACCCCCGGCCTACCCTGCCCGTATGCCAGCAGACAGTCCCCGGCCGCGGCTCGTCCTCGGTGCCGCCGCCCTCGACGTGACCCTCGTCGTCGTGTTCGCCGCGCTGGGGCGCCGTGAACACGAGCGGGGAGGGGGGATCGTGGGCGTCCTGGACACCGCGTGGCCCTTCCTCGTCGGGCTGCTCCTGGGGTGGCTGCTGGTCCGGGCGTGGCGGGCCCCGACGCGACCGCTCCACGGGCTGGGGGTGTGGTTGGCCACGCTGGTGGGCGGCCTGGCGATCCGCGCCCTCGTCCTGCACTGGCCGCCGCTGTCGTTCGCGCTGGTGGCGGCCGGTTTCCTCGCAGCCTGCCTGGTGGGCTGGCGCCTGGTCGCCTGGTGGGTGTCCGCGCGCGCCTCGGCGCGGGCTGCGTAGGGTTGTCGTCATGCCAGAACGCGCACCCCTGCGACCTGGGAGCATCTCGCCCCGCCGATCGGTCCCCCGCTCGATCGAACGCCCGGAGTACGTCGACCGACCGTCGCCGGCCCGCAACACCGACCCCTGGGTCCAGCCAGCCGAGGTCGTCGAGCGGATGCGCCTGGCGGGCAAACTCGCCGCGCAGGCGCGTGAGCTGGCCGGCCGCACGGTGGCGCCGGGAGTGACCACCGACGAGATCGACCGCGTCGTGCACGAGTTCCTGTGCGATCACGGGGCCTACCCGTCGACGCTGGGGTACCGGGGCTTCCCCAAGTCGTGCTGCACCTCGCTGAACGAGGTCGTGTGCCACGGCATCCCCGACTCCACCGTCATCGAGGACGGTGACATCGTCAACGTCGACGTCACCGCGTACCTCAACGGTGTGCACGGCGACACCAACGCGACCTTCCTCGCCGGCGACGTCAGCGAGGAGGCCCGGCTGCTGGTGGAGCGCACCCACGAGGCGCTGGCGCGAGCCATCCGCGCGGTGCGCCCGGGACGCCAGCTCAACGTCATCGGCCGGGTGATCGAGTCCTACGCCAACCGCTTCGGGTACGGCGTGGTCCGGGACTTCACCGGGCACGGCATCGGGCGGTCCTTCCACAGCGGCCTGGTCATCCTGCACTACGACGACCCCTCGGTGGAGACCGTGATCGAGGAGGGCATGACCTTCACGATCGAGCCGATGATCAACCTCGGCACGATCGAGTACGACATCTGGGACGACGACTGGACGGTCACCACCCGGGACAAGAAGTGGACCGCCCAGTTCGAGCACACCCTGCTGGTGACCGCCGACGGGGCCGAGATCCTCACCGTCCCGTGAGGCCGGGCCCCGACGGCGGCAGCCCGGTCAGGCCAGGGGGAGTTTGAGCAGCGCGTTCTCCACGAGTTCCGGCAACGCCGGGTGGATCCAGTACTGCCGCCGGGGCAGCTCGGTGGCGGGCAGGCCGAAGCTGATGGCCTGGATCAACGGCTGGATGAGGGTCGCAGCCTCCGGCCCGATCAGGTGGGCCCCGAGCAGTGCCCCCGTCTCGGGGTCGGCCACCAGCTTGCAGAACCCCGTGGAGTCCTCCAACGCCCACCCGTAGGCCACGTCGCCGTAGTCCTGGACCGCCGTCACGTGCCGGACGCCCCGCGCCCTGGCCTCCTCCTCGGTCAGCCCCACCGAGGCGACCTGCGGGGAGGAGAAGACGGCGTGCGGCACGTGCCGGTGATCGCTGGCCATCAGGTCGTCCGGGCACAGCAGGTTGTGCCGGACCACGCGGGTCTCGTGGTTGGCGACGTGCTTGAGCTGGAACGGCGAGCTGAGGTCACCCAGCGCCCAGACACCGGGCAGTGAGGTCCGCTGGTACTCGTCGACCCGCACCCTGCCGTCCGGGGTGAGGTCGAGCCCGGCGGCCCCCGGCTCCAACAGGTCGCTGTTGGGCACGCGGCCCGTCGCGACCAGGACCTCCTCCGCCTCCACGGTCTCCTCACCGTCCGGCCCCCACAGGACCAGGCTGGTGACCCCGCCCGACCGGGTCGCCCGCAGCGCGGTCCGGCCCAGCCGCACGTCCCAGCGCTGGGAGGCGAGCTCGGTGAAGCGGCGGGACACGTCGCCGTCCTCCGCCCTGAGCAGGGCGTCTCCCCGGTTGACCACCGTGACCTCCACCCCGAAGGACGAGAACACGTGGGCGAACTCGGCGGCGACGAAACCCCCGCCGAGGATGACCATCCGGGCGGGCAGCTCGTCGAGCCGCATGACCGTGTCGCTGGTGTGGAAGCCCGCCTCCGCCAGGCCGGGAACCGCCGGCACGAAGGGCCGGCTGCCCGTGGCGAGCACGATCTGGTCGGCCTGGATCAGCGTCGACGGCCCCCCGTCGCCCGGATCGACGCGCAGGGCCCGTTCCCCGGCGAAGGCCGCCGTTCCCTGGTGGAGCGTGACGTTGGGGCTGCCTTCCGCCCGGTACTGGCGGCCGCCGGCCGCGATCGGGTCGATGCGGTCGAAGATCCGGTCCCGCACGTCCCGCCACCGCACGCCCCGCAGGGTGGCGTCCACCCCGAACCGGGCCGAGTCGGCGGGCGTGGCGGCCAGGTCCGCGGTGTGGACGAACATCTTGGTGGGGATGCAGCCCACGTTGAGGCAGGTGCCACCGAAGACGCCGCGCTCGACGATCGCCACGTCCCAGTCCGCGAAGCGTTCGTCCAGCAGCGAGTTCCCGGAGCCGCTGCCCACGATGATCAGGTCGAATGTCCGCATCCGTGTTCCCCGTGCTCGTCGTCCGGGCGGGTCGGGTGACCGCGCCATCAGGTGGAGCCCCCAGGGCCGGTGACGTGGGCCTCCGGGGTCTCCGCGCGCCCGGCCGGCCGAGCCGGGCGGGAGTCGACAGTGTGCAACCCGCTGAGCAGCCCGGTCATTCCACGGCCACCGGGAACCAGGACCAACGCCACGACGTGCAGGGCGGCGAGCCCGAGGGCCAGCGGCGCGCCCGGCGCCCATCCGGCCAGCGCCGCCGCGGCCAGGACGCCGAGACCGCCCAGCCCGACGAGCCAGGCGACGAGCAGCCGGCCGGCCCCCGGGCGCCGCCGGCCGACGCGGTGGAAGCGCAGCATGACGACGTGCTGCCCCGGGGTGCCGCCGGTGGCCAGCAGGACCAGGAGCACCACCAGCGCGGGCAACGACCACGGCGTCAACGCCGGGAGCAGGACCATCCAGCCGGAGTCGGCGAGCGGCGCGGCGGTGCGCAGCGCCCACTCGACGGGCAGCAGCGCCAGGTTGCCGCCCAGCCACATCAGGAGGAGGTCGCAGAGCATGCCCAGCAGACGGCGGCCGGCGGTGACCGGTCGTGGCGCTCCCGGGTCCGGCACGGCCCGCTGCCCGGGGACCAGTCGCAGCAGGGGTGCCAGCACCACTCCCACCCCGGTTCCCACCGTGTTGGCGATGAGGTCGTCCACGTCGAACAGCCGGTAGGGGCACGGGTAGACGAACCAGTTCCCGGTGAGCTGGGTGAACTCCACGAACAGCGTCGTCGCCACGCCGATGGCCAGGGTGGCGACCACCCCTCGTCGGAACATGTGGCGCAGGAACATCCCCAGGGGCACGAACAGCGCGATGTTCATCGCGAACTGCTGGAAGTCGGCGTCCATGACCACGGCGCGGAGACCACCCGTGGCGTGGACGCCGGGCAGGCCACGCAGACTCCCCAGGGCCTCGAGCTGTGGTCGCTGGCCGCCGTGGTAGGAGCAGAAGTCGGGTACCAACGGCGGCATCGGGACCAGGACGTAGGCGACCAGCGCGAGCACGTACACCAGGAACGCGAACGCGAGGGCGGCGTGCCCGACTCCCAACCGGCCTCGACGGCGGTACTGGCGGGCCACGTAGGGGACGAACAGGACGATCGCCACGGTGAGGGCGACGCTGGCCGCCATCACGCCCGGCAGCACCCGCACCCCGAGCTCGCCCACGTCCGGCCCCCACCGCTGTTCGCTCGTTCGTCGTCGTTCGAGACCACGACCAGGGCCGCGCGGCTGTCCGGGTGCGGTGGGCTCGGCCACCAGGTTAGGCGGTGACCGAACCCCTGCCGGGACACCGGCCCGCCCGCACCTCGGGTGCGCGGAGGGGGTGTGCTGGGGAACTGGTGGTCAACCGCTGGTGGCGTAGGTGGCGGTCAGCTCGGCCCTGGCCAGTGTGTGGAACGCGAGGTTGAAGGACACCACGGCGAGACTTGCCTCACCGTCGACCTCCAACCGGGGGACGTCGACCGCGTGCACCACGAAGTAGTAGCGGTGCGGGTGGTCGCCGGGCGGCGGCGCGGCGCCGGTGAAACCGTGGCCACCGAGGTCGTTGCGCACGTGGAAGGCACCGGCGGGCAGGGTGTCGTCGGACGCGCCCGCGCCGGTCGGGAGGTCGGTGACGTCGACGGGCAGGTTCACCACCCCCCAGTGCCAGAACCCGGAGGGCGTCGGGGCGTCCGGGTCGAAGCAGGTCACGACGAAGCTCCGCGTCGCCTCCGGGAAACCCCGCCAGCTGAGCTGGGGAGAGGTGTCGCCGTGCGCGGCGACCTGCGCGTCGGGCAGGGTCTCGCCGTGCCGGATGTCGGAGCTGGTGACGGTGAACGAGCCGACCTCGGGCAGCAGGCGGTAGGGGTCGGGTGCGACGGGGCGGTCCAGGCCCATGTCAGGTGGTCCTTCCTCGTTGTCCGGTGTCACCACCACCGCGCCGAGGGGTCCGGGCTCCACGGGGCCCGGGAGGGCGCGGCGCGGGGTGGCGGGTCCACAAACGACTGTAGTCAGGGTGGAACCGGTGGGCTGTTCGGGCGAGTTCGCCCGCTTCGCCCGCGAGCGGCGATCGACGTCCTGGACGCCGCGCCACCGCGGTGCGGCCCCGTCCCCCGGTGGTGAACCGGTGGGGGGCGGTGACAGGATGGTGATCAGGCGGCGCCGGTCCGGCTCCGGTGCCCGGGCACGACGAGGGGCACGGTCGAGGTCATGGGACAGGTCAAGGCGGAGGTGAGCCGCGAGTTCGACAGGCCGGCCACCCAGGTCTTCGCGGCGATGGCGGACTACGAGGACTCGCGCAGCAGGGTGCTCACCGAGAACTACACCGAGTACGAGGTGCTCGGCGGCGGCCGGGGCGAGGGGACCCGGGTCCGGTGGAAGCTCCAGGCGACGAAGAGCAGGGTGCGGGACTGCGTCATGAACGTCTCCACCCCGCGTGAGACCCAGCTGGTGGAGTCGGACGAGAACTCCTCCCTGGTGACCACGTGGACGGTCGTCGACCTCGGTGACGACCGCAGCCGGGTGACCGGTGTGACGACCTGGGAGGGCGCCGGTGGCGTCAAGGGGTTCTTCGAGCGCATCTTCGCTCCCCTCGGCCTCCGGAAGATCCACCAGCGGCTGCTGGACAACGTCGCGGGCTCGTTGTCCTGAACCCGGCCCGGGCTGGCGGGAAGCGCGCCGGCCCGAGCGCGGCAGGACCAGGCGGACGGTCGTGGCCGGGGAGCGAACCCCTGCGCTCGGCCGTCCGTGGGGGCGCCGGGTGGGGCGGCGGGAGATCCCGGGAGCCCGGCGCGGTGGAGCGGCCGCGCTGACCGGCCCCCGCGCGTTCGCGGCGGGCCTCGGTCCCCACCGGAGCCCCCGAATCGGGCTCGAGCGGCCGCGCGGGCGGTTAGCGTGGGGGCACCGGACCACGGCTTGAGGGGACCCGACGATGCCCACCGACGAGATCGACCACGGCGACCGCGCGCACCGCGTCCGTTTCCCCGGGATCAGCCCGCGTGCCTACGAACATCCCGCTGACCGCGGCGCGCTGGCCACCCTGCGGGCGGTGCCCCCCTTCGCCGCCGTGCTGCGCGCGGTGAACGGTATGACCGGGGAACGCAGCGAACGGCTGCTCTCGCTCGCCTCCCACATCAGGGTCTCCGAGTCGCAGTTCCCGGAACTCCAGGCGTTGCGGCTGGAGTGCGCGTCCACTCTCGACCTCCCGGAGGTCCCGGAGGTCTTCGTCGCCCGCGACCCGAGGCCGAGCGCGGAGTGCGTGGGCATGGACCGGCCCTTCATCGTGCTCACCACCGGGCTGGTCGAGGTGATGGACACCCGGGAGCTGCGCTTCGTCATCGGGCACGAGATGGGGCACGCGCTGTCCGGGCACGCGGTGTACCGGACGTTGATGAACCGGCTCCAGTCCATCATGGCCGGGATGGGCTGGATGCCCGTCGGTTACTGGGGGATCCGCGCGGTGCTCTTCGCGTTGGCCGACTGGTACCGCAGGTCGGAACTGTCCTGCGACCGGGCGGGTCTGCTCTGCGCGCAGGACGCGGGCGCCGCGCTGCGCGCTCACATGATCATGGCGGGTGCCACCGATCCGGACCGGATCGACACCGCCGAGTTCCTCCGGCAGGCCCGGGACTACGACGGGGTGGAGTCGTTGTGGGACAGCCTGTTGAAGCTGCGCCAGTTGGAGATGCGCACCCACCCGCTGGCCGTGGTCCGCGCGGCCGAGCTCCAGCGGTGGGCCGCTGGGGAGGAGTACCGGTCGATCCTGTCCGGGGACTACCCCCGCCGGGAGACCGACGACCCGGCCGCGGACTGGCGGTCGGACATCAGGAAGGGCGCCCGCTCCTACACCGAGTCGCTGGCCCGGTCGGCCGATCCGCTCGCCCGGCTGGCCAACGAGGTCGGCGGCGCGGTGAGCGGCGCGGCGAGCAGGTTCTGGGAGCGTTTCGGGGGATCCCCGGCGGGTGGGGGGCGTAGCGGGGACGAGCCGGCGGACCCGTCGGCGGGGACCGAGGGCACGCGGGGCCCGGGTTCCGAGACTTCCTGACGGCCCGCCGACCGAGCACCCCGAACCCGGCCGGCAGAACGGCGGGGCGTTGGTGGTCACGGTCCGTGGGACGCGGCGCGGCTGATCCGGGCACGTGGATCACCTGCCCGGATGATCTCGGTGGTCCCCACTTGTCCGCCCCACCCCGCCGGGGTTGCCTGGACCCGGGAGCGGGGTCGGAAGGGGCAACCGATGCGTGGGTACGGAGGAGGCCGACGAGGCCGCGCCAGGAGGGTCGCCGGGCTGGTCCTGGCCGGGATCGTGCTCTCCGGGGTCCTCGCGGCGGCGGCGCCGGTGCGGGTGGACCGGACGGCGTCCGAACCCCGGACGGCCGGTTCCCGGACCAACGTCGTGGGCGGTGAGCCCGTGCCGGTCGACGACTACCCCTGGGCCGTCCACCTGACCACCCGCAACGGCGTGGTGTTCTGCGCCGGGGCGCTCGTGGCGGCGGACCGGGTCGTCACCGCCGCCCACTGCCTGCTCGGCGCGAGCGCCGACCGGGTGCGGGTCGTGGTCGGTCGGACGGACAGCGGTGGCGCCGAGGGCCAGAGCCTGCCGGTCGACGGGCTGTGGGTGCACCCCGAGTTCACCACGGCGGTGCGGGGCGACGACGTCGGGCTGCTGCGACTGGCCACCCCCGTCGACCGGGCCACGATCGCGGTGGCCGGTCCGTCGGACACCGACCCGTACCGCCCCGGCACCGCCGCGGAGGTCGTGGGGTGGGGGGCGGAGGAGGAGGGCGGCCTGCCGGGCGGGCCGCTGCGCCGGGTCGTGGTGACGACGCTGTCGGCCGAGGACTGCGCGAGGAGCCATCCCGAGGTGGACGGCGACCGGATGGTCTGCGCGGAGGACGCGGCGGGCCGGGCCGGCTTCTGCCAGGGCGATTCGGGGGCCCCGCTGGTCGCCGAAGGCCTGCTGGTGGGCCTCGCCTCGTTCTCGGCAGGGTGCGCCTCCGAGGATCCCGGCGTGCACACCCGGCTGTCCCACCACCGCGACACCCTCGAGGGCGTGGACGACTGGAGCCGGGCGGTGGCGGGGACGCCCGGCGCCTGAACGGGGCGTCCCGGGCGGGTCAGCCCACGACCAGGCCGACCGAGAGGACCATGAAGACGCCGGCGCAGACGGCGTCGAGGCCGGCGGTGACCCGGGGTCGGCGCAACCGTTCGGAGAGCAGTCCCGCCGCCAGCACGATGCACAGTTCCAGGACCACCGCCACCGCCAGCAGCACGACGCCGAGGACCGCGAGCTGGAGGGTCGAGTTCTGCGCCGAGCCCATGAACTGGGGCAGGAGGGCGAGGGTGAACAGCAGCATCTTCGGGTTGGTCAGGTTGGTCAACAGCCCGCGGAGGTAGGGGCGGCTGGTCTGGGTCGCCGGTGGGGGAGTGCCCTCCGGCGTCCGGTCACCCTCGGCACCGGGCGGGTTCGTCCGTCGGCGGACCAGCCCGAGGAGGATCGACACCGCCAGGTAGGCGAGGTAGCCGGCACCCAGCCACCGGAGGGCGGTCAGCGCCGTGTCGTTGCGCGCCACCAGCAGCCCGACCCCCGACACCACCAGCACGATGTGCAGCGTGACGGCCGTGTGGATGCCCGCGAGGGTCGCCAGCCCCGCCCGGGTCCCGGCCAGCACCGAGGTTCGCAGCAGGAGGAAGACGTCCACGCCCGGTGTGAGGACGAAGACGGCGGTGGCGAGCAGGAACGCCGGCAGTACCGAGGCATCCCAAGACATTGAACAGCTCCTCATGAAATGATCTGGTGATCGAGCGCACATCTGCAGGAAGAATTCCTGTGCTTCTGCAGGCTAACACGACAATATTTCTCGCTCGTGGGGTGTGGTTGTGCGGACCACATGCGGAGAGCGCCCGGTTCGCTACGCTGAGTTCCCTACTGGTGTCCGACGAAAGGAGCAGCAGTGCTGCGCTCTTCAGTCCAGTCGCGCCGCGGGAGGTCGTGGCTGCGGGGCCTCACCTCGTCCCTCGTGCTCGCCCTGGTCGCCGCTCCGGGACTGGCCGCCCCCGCGGCGGCCGCGCTCGACGAACCGGACGCCCCACCCGCCCAGGCCCGCATCGTCGGCGGGACGAACGCCACCACCGAGCAGTACCCGTGGGCCGTCACACTCCTCAACGACGCCGGCAAGCAGTTCTGCGGTGGAGCGCTCGTCGCCGAGGACAAGGTCGTGACCGCCGCGCACTGCGTCGCGGAGACCCGGTCGGGAAAGGTGACCACCCGCAGCCCGGCCAGCCTGCGCGTCGTGGCCGGGCGCACCGACCTGCGCACCGGAGGCGGTCACGACGTGGCCGTCAGCCGGGTGTGGATACACCCCGAGTACGTCTCCTTCACCCAGGGTGAGGACATCGGCGTCCTCACCCTGAGCGAGCCCCTGCCCTACCGGACGCTGCCCGTGGTCGAACGGGACGGGCAGTCCCACTACCGGGCCGGAACCGAGGCCACGGTCATGGGGTGGGGCCGCACCAGCGAGAACGGCGCGAGTTCGAGCGTCCTGCGGGAGGTGGTCGTCCCCCTGGTCACCGACGCGGACTGCGCCAGCGCCTACACCCAGTTCACCGCCCCGCAGATGGTGTGCGCCGGCTACCCCGAGGGCGGCCGGGACGCGTGCGCGGGAGACTCCGGGGGCCCGCTGGTCGTCGGCGGCCGCCTGGTCGGGCTGGTGTCCTTCGGGGACGGGTGCGCGCGTGCCGGCAAACCCGGCGTGTACACGCGGGTGCTGACCTACCGCGACGAACTGCTCGCGCAGCTCGGCCGCTGA

Protein sequences of DBSCAN-SWA_2

>CP025990|4572796:4616063|4590513_4591620_+|AUS80149.1|DBSCAN-SWA
MTALPLVFDAPRRGLPPRHLADLSPEDRRSAVAELGEKAFRATQLSHHYFGRLSVDPESMTDIPSATRDRLVESLLPTLFTQVREVTTDNGTTRKTLWRAHDGTLVESVLMRYDDRATVCVSSQAGCGMACPFCATGQGGLQRNMSTAEIVDQVRSAAAAMRDGLLPGGAGRLSNVVFMGMGEPLANYKRVVAAVRRLCEPAPAGLGLSQRSITVSTVGLAPAIRKLADEDLQVTLAVSLHTPDDELRDTLVPVNTRWSVDEVLRAARYYADRTGRRVSIEYALIRDVNDHPWRADLLGRLLRQHLGHLAHVNLIPLNPTPGSEWDASPKPVEREFVRRVREAGVSCTVRDTRGQEIAAACGQLAAQE
>CP025990|4572796:4616063|4600903_4602061_+|AUS80155.1|DBSCAN-SWA
MSVELGMPTIPPPVLAPRRTTRQLRVGAVGVGSDHPVSVQSMTTTVTADINSTLQQIAELTASGCDIVRVACPSQDDADALPAIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIKKFDDKVKEIAQAARDHGTPIRIGVNAGSLDPRLLAKHGKATPEALVESALWEAGLFAEHDFHDIKISVKHNDPVVMVRAYELLAESCDYPLHLGVTEAGPAFQGTIKSAVAFGALLRQGIGDTIRVSLSAPPVEEIKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLADEVTAGLDGLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEHKIVETLIEEAMRIAEEMDGDPSTLVGEPTVTVS
>CP025990|4572796:4616063|4574869_4575322_+|AUS80134.1|DBSCAN-SWA
MAVKIKLMRLGKIRAPHYRIVVADARTRRDGKAIETIGKYHPTREPSFIEVDSERAQYWLGVGAQPTEPVQRLLELTGDWQKFKGLPVPEGALKQAEPKPDKQALFNAALAAAGEEPVTEATTPKKKSTKKSDKADASEAEGEKNEGGQE
>CP025990|4572796:4616063|4612186_4613299_+|AUS80165.1|protease|DBSCAN-SWA
MPTDEIDHGDRAHRVRFPGISPRAYEHPADRGALATLRAVPPFAAVLRAVNGMTGERSERLLSLASHIRVSESQFPELQALRLECASTLDLPEVPEVFVARDPRPSAECVGMDRPFIVLTTGLVEVMDTRELRFVIGHEMGHALSGHAVYRTLMNRLQSIMAGMGWMPVGYWGIRAVLFALADWYRRSELSCDRAGLLCAQDAGAALRAHMIMAGATDPDRIDTAEFLRQARDYDGVESLWDSLLKLRQLEMRTHPLAVVRAAELQRWAAGEEYRSILSGDYPRRETDDPAADWRSDIRKGARSYTESLARSADPLARLANEVGGAVSGAASRFWERFGGSPAGGGRSGDEPADPSAGTEGTRGPGSETS
>CP025990|4572796:4616063|4611465_4611906_+|AUS80164.1|DBSCAN-SWA
MGQVKAEVSREFDRPATQVFAAMADYEDSRSRVLTENYTEYEVLGGGRGEGTRVRWKLQATKSRVRDCVMNVSTPRETQLVESDENSSLVTTWTVVDLGDDRSRVTGVTTWEGAGGVKGFFERIFAPLGLRKIHQRLLDNVAGSLS
>CP025990|4572796:4616063|4575571_4576120_+|AUS80136.1|DBSCAN-SWA
MVNTARLGESALLVGRVVRPHGVRGELVVEVRTDSPEERFAVGTTLDGRLRDGSTRTFTVTAARNHSGRLLLTLDGVVGRDAAEELRGTLLTVDRAALPPTGDPDEYYDHQLEGLRAELPDGSEIGQVVEVVHGAGADLLSIRAPERADRVLVPFVRAIVPEVHLDEGRLVVDPPEGLLDET
>CP025990|4572796:4616063|4592747_4592996_-|AUS80150.1|DBSCAN-SWA
MDRYSGGDVVDPRDEPSAEWGWHGEWPRGRRVAGWAVAAIMFLMLIGNHEGHVETIWLIGIGLGMIGFLIWDQTRRRTPWRN
>CP025990|4572796:4616063|4614371_4615025_-|AUS80167.1|DBSCAN-SWA
MSWDASVLPAFLLATAVFVLTPGVDVFLLLRTSVLAGTRAGLATLAGIHTAVTLHIVLVVSGVGLLVARNDTALTALRWLGAGYLAYLAVSILLGLVRRRTNPPGAEGDRTPEGTPPPATQTSRPYLRGLLTNLTNPKMLLFTLALLPQFMGSAQNSTLQLAVLGVVLLAVAVVLELCIVLAAGLLSERLRRPRVTAGLDAVCAGVFMVLSVGLVVG
>CP025990|4572796:4616063|4584258_4585074_+|AUS80143.1|DBSCAN-SWA
MANYTAADVKRLRELTGSGMMDCKKALEESAGDLEKAVELLRIKGAKDVGKRAERTTANGLVAADGGVLVELNSETDFVAKNAEFQELAAKVVQAAKETRPADVAALNAASVGDKTVADAVRELSAKIGEKLEVSKVAVFDGQVAVYLHRRAADLPPAVGVLVEYTGSNEDAAKAAAMQVAAMRAKYLTRDEVPADIVANERRIAEETAREEGKPEQALPKIIEGRVNGFYKDVVLLEQSSVQESKKTVKAVLDEAGVTITRFARFEVGAS
>CP025990|4572796:4616063|4586613_4587531_+|AUS80146.1|DBSCAN-SWA
MMAAGDHDAPGVDGETGHHQHTSTPPGTAVTGGTASRAGRNLPAAIAVGLGLGALLLAALLFWRHLFVAIVAAAVAVSTMELHRTLGRAAGVRLALAPLLVGGQAMIWLSWPFGTVGVLASFALTVVACLLWRFRGGADGYLRDTSASVFVAAYVPLFASFAALLVLSPDGAARTIAFLLAVVCSDTGGYVAGVLFGRHPMAPSISPKKSWEGFAGSLLAGVAAGVGSFVFLLDGAWWQGAIFGAALVVTATTGDLIESLVKRDVGVKDMGSLLPGHGGIMDRMDSLLPSAVVSWLLLTVFLPLA
>CP025990|4572796:4616063|4579486_4579813_+|AUS80139.1|DBSCAN-SWA
MSSEDLEKYETEMELQLYREYRDIVGQFSYVVETERRFYLANAVDVQVRNSEGEVYFEVRMSDAWVWDMYRPARFVKNVRVITFKDVNVEELDKPELRLPENGPFSSG
>CP025990|4572796:4616063|4575318_4575558_+|AUS80135.1|DBSCAN-SWA
MSVLADALEHLVRGIVANPDDVRVQLITTRRGRTLEVHVHPDDLGKVIGRGGRTATALRTVMAGIGGRGLRVDVVDTDR
>CP025990|4572796:4616063|4573713_4574622_+|AUS80133.1|protease|DBSCAN-SWA
MNQVDGGEEPRRATPGPPGHGTAEPDETVTDIPGEERATRTAGPGAEARRDGGPPTAEPRPDPGADGAPVRTHRWGLGVFFLAQLVFLLSSVFLVAPLGPMDPDSSLRETVLIVGLVLPTLLAAGVVLAATRLRGNGPRRDLGLEWSWADVRTGLKYGALCMGLAYVGAMFWSQWVGEENANSAVGSLVEGLQLSPGLAVLLFLHVFLIAPTCEELIFRGALWGAMERLRWSRWTVFVSSTAIFAVAHLEPERTPLLLLIGIPIALARLYTGRLLASIVAHQMNNLLGAVGLLLMALGVIPP
>CP025990|4572796:4616063|4605274_4605544_-|AUS80158.1|DBSCAN-SWA
MVEPSGRRRFGAWALVRDPENLAPGTRVRVHYNRGLLSATVLVGDLIACGEDMIRLSGSHLCDLIAPRVDGDQPAMVERWSYPDEAPAQ
>CP025990|4572796:4616063|4607848_4609237_-|AUS80162.1|DBSCAN-SWA
MRTFDLIIVGSGSGNSLLDERFADWDVAIVERGVFGGTCLNVGCIPTKMFVHTADLAATPADSARFGVDATLRGVRWRDVRDRIFDRIDPIAAGGRQYRAEGSPNVTLHQGTAAFAGERALRVDPGDGGPSTLIQADQIVLATGSRPFVPAVPGLAEAGFHTSDTVMRLDELPARMVILGGGFVAAEFAHVFSSFGVEVTVVNRGDALLRAEDGDVSRRFTELASQRWDVRLGRTALRATRSGGVTSLVLWGPDGEETVEAEEVLVATGRVPNSDLLEPGAAGLDLTPDGRVRVDEYQRTSLPGVWALGDLSSPFQLKHVANHETRVVRHNLLCPDDLMASDHRHVPHAVFSSPQVASVGLTEEEARARGVRHVTAVQDYGDVAYGWALEDSTGFCKLVADPETGALLGAHLIGPEAATLIQPLIQAISFGLPATELPRRQYWIHPALPELVENALLKLPLA
>CP025990|4572796:4616063|4615208_4616063_+|AUS80168.1|protease|DBSCAN-SWA
MLRSSVQSRRGRSWLRGLTSSLVLALVAAPGLAAPAAAALDEPDAPPAQARIVGGTNATTEQYPWAVTLLNDAGKQFCGGALVAEDKVVTAAHCVAETRSGKVTTRSPASLRVVAGRTDLRTGGGHDVAVSRVWIHPEYVSFTQGEDIGVLTLSEPLPYRTLPVVERDGQSHYRAGTEATVMGWGRTSENGASSSVLREVVVPLVTDADCASAYTQFTAPQMVCAGYPEGGRDACAGDSGGPLVVGGRLVGLVSFGDGCARAGKPGVYTRVLTYRDELLAQLGR
>CP025990|4572796:4616063|4605536_4606523_-|AUS80159.1|DBSCAN-SWA
MAGGEPGAVCPETAAPPALPEAAAPAGAPPSRTPRPRPVPPADRTSGRLPTSRRRPRPPAGPPPRPPLAAPTRRARGRPGADPVPATDVRRRPERFAPPTPASVGVDRVHRPASRGPRSCRTAGVHRPRWASPVTTTRRAAPVDRRRQGGPRQWTGGGHRGPGCLGGGRDRAGGAGSRSGRPTTRRRHPGWPRRPRRRPLRPVWTEVPAKPGGDRSAAGDAPPGHAEIVILPGRLVIVTTAWPPDDPEEQVAAVRFATSWWRYPGSLEQAARERYGVTGARFWQGINSLITERHVMAALPNECNRLLRLRDRRRVARTRRRGGYRDCG
>CP025990|4572796:4616063|4592013_4592499_-|AUS81880.1|DBSCAN-SWA
MSITQRLVHHNAAHPISCADLPTEPASKLAVVACMDSRMDVFQLLGLRVGEAHIIRNAGGVITDDVIRSLAISQWRLGTEHIILLHHTRCGLRTFTDAEFKAQMRQEVGVTPEWSVECFEDESVDVHESKERIKRSPFIRHAHSIRGFVVDVDTGLLHEVD
>CP025990|4572796:4616063|4605062_4605275_-|AUS80157.1|DBSCAN-SWA
MPMLIGLKSGCPNCHGTGMDPLDATSLCPTCRGLSEEVEGRLSTGSSPVPLPLVVERARNHRHSPWRRWT
>CP025990|4572796:4616063|4576294_4577113_+|AUS81877.1|tRNA|DBSCAN-SWA
MRIDVITIFPEYLAPLRAALLGKAVDRGLVEIGVHDLRSWTHDVHRTVDDSPYGGGPGMVMKPDVWGEALDAVCPAPDPEDAGGRAPVLVVPTPAGRRFDQALARELAEEPRLVFACGRYEGIDQRVVDEAEGRMRVLEVSIGDYVLVGGEVATLVMVEAVARLIPGVLGNPVSASEDSFSDGLLEGPCYTRPEVWRGRAVPDVLRSGNHAAVDRWRRDRALERTLRRRPDLLDALPPEELSRADRAFLAGLEEESPQVGADGGGAGAGPIS
>CP025990|4572796:4616063|4602189_4603026_+|AUS80156.1|DBSCAN-SWA
MLKLAGARLLTEREGLAVRSALVADPVVSCMVAARVESVGLDPWRLGGELWGVGSRLGGLCFSGVNLIPLRGGRAASRAFAERALSQPRHCSSLVGPADQVLEMWQQLEPGWGPARDVRPNQPLLAMSAPPSVAPDPLVRQVRLDDLERYLPAAVAMFTEEVGIDPQGEDGGASYRARVAELIVNGRAFARFEGGEVVFKAEVGALSARVGQIQGVWVHPEHRNRGLAAAGTAAVVDRLSGWMGRIASLYVNDYNLPARAVYRKVGFSEVGRFATVLL
>CP025990|4572796:4616063|4599503_4600715_+|AUS80154.1|protease|DBSCAN-SWA
MIGVILFAIGIGVSIALHELGHLAAAKAFRMKVTEYFVGMGPKIFSFRRGETEYGLRALPVGGYCRITGMTSLDEVDPVDAPRAMNRKPVWQRVVVLCAGSATHFMLAFVILLTMAVTMGLPNISGRAVVAEASSCVPPDQDLETYEYAECTPGQDPAPARDAGVLPGDEIVAVNGEATGNYTEVQAALVEQSGDSATITVLRDGSEQELTIPIVPVQRVMVNPETGEAEKVETNALGVSFPNYLHFTAAQALPGTLTFTGEMFVHTWERLLELPSRVPAVIDAILGAERDPNTPVSMVGASIIGGDAVAGGYWELFLFLLATLNLFIGVFNLLPLLPLDGGHVAVNLYEKARDTIRGWRGKAKGAPVDYTKLLPITYAAVFIGGAFMLLTLTADIVNPIRLR
>CP025990|4572796:4616063|4596010_4596835_+|AUS81881.1|DBSCAN-SWA
MAGWAALAPAGLWLGAFFVVPVALVAQYSFATRDLGIARVVLPWTLDAYRLAVDPAVLPIFWRTAAYSLSATLACLVIGLPLAWFVARHAGRWRLVLLGAVLVPFWASHLARIYAWKALLAEDGPVNRVLGLVGLDRPGGLLLTDVAVVVGLTYGYLPFMVLPLYVVCRRFDPRLLEASQDLGHGRLGTFVRVVLPGLAPGVVAGSLLVLVPSVGDFVTPALLGGVNQLTFGSVIDDQFRGGNNWPLGSALAVLLLAAVAVLWVARGRRAREVL
>CP025990|4572796:4616063|4594712_4595873_+|AUS80152.1|DBSCAN-SWA
MADRDAVRIARLWDGRERPVTRRAMLRSTAFFALAAHGAAGCAISEPVEPRRTDPRATRAVNEVEEPVLNFFNWTDYVDEDTIPGFEDETGISVTYDNFSSNDELEAKLAAGGSGYDLIVPSDNFLRRFLRSDLLSPLDHDLIPNLDNLDRRFREAEYDPDNRYSVPWAWGTTGLAFSRQALGGADVTSLDAFRLAAARGRSALLDEARDAMALGLLGAGHDPNTTDPGELEDAVEYLLDLKGVLGQITSDVIEPLASGQAPLAQAWSGDVFQAMETNPELDFVIPEEGGLSWVDLLCVPRSAPHAANAHRFIDHILRPEVGGRLANAIQYGSPNAAARPFVDAELLADERIYPSPEALARVPFTRDLGPEVEGRYADAWTRVKTG
>CP025990|4572796:4616063|4589625_4590336_-|AUS80148.1|DBSCAN-SWA
MLPEDDRFEPIGDPHFDRLVGETRSAAVAGHLLDWLALAHSAAAELQRVRRRSARGSWANGWSFGTDRYQYLLATASGLPDARVNPAFQSMTIGIGNCALYQYRAKTGSPLTSVLDDTELQRRLVRPPEEPPGLFPANHAITGGRDLLFLPWTGSEAAGLSGAWVGQGSADRDYRIRWSWLWPLTSFTRGHARTAGLGGPLTARPAPTGTTGWNPHDLPELPLRHRARPQEGTSGA
>CP025990|4572796:4616063|4572796_4573576_+|AUS81876.1|protease|DBSCAN-SWA
MGSVQDGRDPGLHDRYWEAQLEAGARNSLHWGFLAFFVGWAAYYLVAGLIGAILAGQFQEFDPLAPPPMGPLLLVSLIPNLFLGLGPAVLSWWKGQGLRRDFGIVPKRRDWKVGLLSGGIGLVAAFVMAILLMSGSLDENGESSGINSLGQLAQGQAIWILLFSLFVFIGAPLTEELLVRGALWGALEQYRVPRYAILLLTTFVFALIHEEPERTPVLLVGGLAIGIARMITGRVAAAIIAHATYNLLPAVVFYAQFSG
>CP025990|4572796:4616063|4613491_4614352_+|AUS80166.1|protease|DBSCAN-SWA
MRGYGGGRRGRARRVAGLVLAGIVLSGVLAAAAPVRVDRTASEPRTAGSRTNVVGGEPVPVDDYPWAVHLTTRNGVVFCAGALVAADRVVTAAHCLLGASADRVRVVVGRTDSGGAEGQSLPVDGLWVHPEFTTAVRGDDVGLLRLATPVDRATIAVAGPSDTDPYRPGTAAEVVGWGAEEEGGLPGGPLRRVVVTTLSAEDCARSHPEVDGDRMVCAEDAAGRAGFCQGDSGAPLVAEGLLVGLASFSAGCASEDPGVHTRLSHHRDTLEGVDDWSRAVAGTPGA
>CP025990|4572796:4616063|4597685_4597952_-|AUS80153.1|DBSCAN-SWA
MGILGWIVLGLLAGLIAKAIMPGRDPGGIIITLVLGVIGAFVGGFIGRAIFDTDLGSFFEIRTWLLAILGSIILLAIYRLVTGRRAHA
>CP025990|4572796:4616063|4581469_4582222_+|AUS80141.1|DBSCAN-SWA
MEAGIVALWRSYGAARQQALRDRLVLHYAPLVKYVAGRVGTGLPAHVDVADLVQSGIFGLVDAIEKFEPERGLKFETYAMQRIRGAILDDLRAQDWVPRSVRSRARDLERAQERLEARLQRTASDGELAHELGIGVSELRDLFAQVQLTSVVALDELIAAGRGSASLAETLPDERAEDPVANLIDGDSRRQLASAIAQLTERDRIVVTLYYFENLTLAEIGRVLGVTESRVCQLHTRAVLRLRTRLTGQS
>CP025990|4572796:4616063|4580313_4581258_+|AUS80140.1|DBSCAN-SWA
MTGQAEAVSSTTAEQLLADYRRHLRAERNLSAHTVRAYLGDLRELLAQLPGAPDAVPLDPLPLDITLLRAWLATRHAEGASRSTLARRAAAARAFTAWATRRGLLPSDPGPRLRAPRVRRALPSVLRPDQAATALRAAERATADGDPVALRDHAVVELLYATGVRVAELCALDVDDVRRADRLLVVRGKGDRERAVPFGVPAERALAAWLERGRPSLTRSDSPPAVFLGVRGGRLGVRAARTIAHQTAAAAPGAPDVGPHGFRHSAATHLLEGGADLRSVQELLGHATLATTQFYTHVTVERLKAIHDRTHPRS
>CP025990|4572796:4616063|4587578_4588340_+|AUS81879.1|DBSCAN-SWA
MAGRRERRGGGVLPSPNIWNWPDLYEVENRAQDPDGVLWDALRAARDWSGADVVDVGCGAGFHLPVFARSAARVVGVEPHPPLAAAARQRVRDLPAVTVHEAGAQRLPLPDAAVDLVHARTAYFFGPGCEPGLVEADRVLRPGGTLAVVDLDATRHSYGRWMRADLPRYDPLAAERFFVERGFSCQRFDVDWRFDDRRSLESVLGIEFSPEIAARAAAEVPGLSFRVGYRVHVRHKPRGPVLPNGATARDDPR
>CP025990|4572796:4616063|4598246_4599491_+|AUS81883.1|DBSCAN-SWA
MPAEAPSSARRVLLLGSTGSVGTQTLDVARRNPDAVRVVGLAAGGANLDALAAQAHDFQVEAIAVPRVGVERDLVAAWRAEAERRGVLAGTAPPRVHTGVRALLDLIESTPSDIVLNAVTGSRGLEPTLAALATGATLALANKESLIAGGPLVLAAAAPGQIVPVDSEHSALAQCLRGGRADEVDRLVLTASGGPFYSRTREDLEAVTVEEALAHPTWSMGRVISVNSATLVNKGLELIEAHLLFGVPYDRIDVVVHRTSVVHSMVTFVDGSTLVQASPPDMRLPIGVALGWPRRLRDVSSPCRFDTTTTWTFEPVDNLSFPAVELARAAGRAGGSVPAVYNAANEEAVEAFLEGRTKFTRILETVERVLAEADEWRRDPSGVDDVLAAEDWARARSRRLLGVTGHAAGSVGKD
>CP025990|4572796:4616063|4578707_4579400_+|AUS81878.1|DBSCAN-SWA
MVRRSLGNWALQSALDRRGLGPVAGVDEAGRGACAGPLVIAACVLRPRDSERLPGLTDSKLLTALARERLYDQVVDRAVAFSVVSVPAERVDTLGVHVANLEGMRRAVARLPVHPGYVLTDGFRVPGLTAPNLAVVKGDLVAACVAAASVLAKVTRDRAMARMDQRYPGYGFAVHKGYCTADHAEALREYGPCAEHRFSYSNVREAAGHRVTSSRTSPVGGGAPEPVAIS
>CP025990|4572796:4616063|4577796_4578651_+|AUS80138.1|DBSCAN-SWA
MSDEATAGEGAGGAGEKEQKKGSFWRELVVLVGIAVVLTIVIQAFIARVYVIPSQSMEETLHGCNGCTNDRVLVDKMTYRFTDPSPGDVVVFRGPATWTENEIPPQRSDNPVVSFFQSIGGLVGMAPPDNREFVKRVIATGGQTVECCDEENRVLVDGEPLDETYVYWQPNRGNTQEAFGPVTVPADHLWMMGDNRNNSLDSRVQGGGGERGSVPVDDVIGKARFIVLPPQRWQGIGDDDPQRTGQALSAPAWHGAIPAGIGLAAAFPTLWIGRRLLSLRRRDD
>CP025990|4572796:4616063|4596888_4597662_+|AUS81882.1|DBSCAN-SWA
MLLATVVGAYAFLYAPILWLALLSFNDSRSVSTFTGFSLRWYAELLTDGQVLDALWLTVRLAASTAVVAAVLGTLAAWALRRPFRGRGLWSTVLAMPLVVPEVVLGVSLLAFCVKLAGIPLGFGALLAAHVTFSLSFVVIVVRARLAGLDPRLEEAAADLGAGPLTRWRTVTLPVLWPAIGAGAAFAFVLSFDDVVTSSYLSGVGGTPLPVLVYGQASRRGVSPEIVALSTSMVVLSTVLLVLAVLVVARRARHLDR
>CP025990|4572796:4616063|4606963_4607821_+|AUS80161.1|DBSCAN-SWA
MPERAPLRPGSISPRRSVPRSIERPEYVDRPSPARNTDPWVQPAEVVERMRLAGKLAAQARELAGRTVAPGVTTDEIDRVVHEFLCDHGAYPSTLGYRGFPKSCCTSLNEVVCHGIPDSTVIEDGDIVNVDVTAYLNGVHGDTNATFLAGDVSEEARLLVERTHEALARAIRAVRPGRQLNVIGRVIESYANRFGYGVVRDFTGHGIGRSFHSGLVILHYDDPSVETVIEEGMTFTIEPMINLGTIEYDIWDDDWTVTTRDKKWTAQFEHTLLVTADGAEILTVP
>CP025990|4572796:4616063|4609284_4610442_-|AUS80163.1|DBSCAN-SWA
MGELGVRVLPGVMAASVALTVAIVLFVPYVARQYRRRGRLGVGHAALAFAFLVYVLALVAYVLVPMPPLVPDFCSYHGGQRPQLEALGSLRGLPGVHATGGLRAVVMDADFQQFAMNIALFVPLGMFLRHMFRRGVVATLAIGVATTLFVEFTQLTGNWFVYPCPYRLFDVDDLIANTVGTGVGVVLAPLLRLVPGQRAVPDPGAPRPVTAGRRLLGMLCDLLLMWLGGNLALLPVEWALRTAAPLADSGWMVLLPALTPWSLPALVVLLVLLATGGTPGQHVVMLRFHRVGRRRPGAGRLLVAWLVGLGGLGVLAAAALAGWAPGAPLALGLAALHVVALVLVPGGRGMTGLLSGLHTVDSRPARPAGRAETPEAHVTGPGGST
>CP025990|4572796:4616063|4603197_4605045_+|AUS81884.1|DBSCAN-SWA
MLLAGALSLTLSGCGVFDSGPGPEQALADFVAAMGAREPERAAALTDSPDGALPTLESVDRALAPEGASAEVIEVRETDGSTHADLDITWELAGDRTWNYHGTARLREIEGDWRLEWAPSVIHPDFGEQQTLAVRTEAAPLPPVLDRDGHVVLDPGVVISVLLDPAATEEQEGDVTEVATVLGDTLNRFDDRITPDSVLEGVSDTEDGHSYLVATLREPDYHSVRSDIHELPGVRFTNQPRLLPVTRDFGSQILPSLRRGVEEANVERAGWRVVSLDATGAEVNTLHHEQPRPAEATRLTLSRAAQAAAEDAVEPFDEQAMLVAVEASTGHVLAVAQNAAADAEGPVALVGQYPPGSTFKIVTAAAALASGQVTADRTVACPATTAIDGRLVPNNDRFDLGDVPFHTAFARSCNTTFATLASDMEPDELAETARQFGLGREFVIPGLATWTGPVPVTDSSAERVEAGFGQGTVLASPFGMALVAATVAAGTTPTPVFLAEDDREPSDAAGAAAGGTSAEPDGPSSAGPVEAPSAQVIDALRPMMREVVTEGTATELAGLPEVHGKTGTAQFGDGSRSHGWFVGYQGDIAFAALVVDGGSSAPATKLAGDFLGSLG
>CP025990|4572796:4616063|4586047_4586605_+|AUS80145.1|DBSCAN-SWA
MIDEALLDGEEKMEKAVSVAKDELATIRTGRATPVMFNGISVDYYGAMTPINQVASISIPEARLAVIKPYDPSQLRVVEKAIRDSDLGVNPSNDGTIIRVVIPQLSEERRRDLVKVAKQKGEDARVTIRNIRRKVKDEIDRIVKDGEAGEDEGSRAEKELQNLTDKYVASVDDLVKHKETELLEV
>CP025990|4572796:4616063|4585178_4585916_+|AUS80144.1|DBSCAN-SWA
MSDPQIDDDHPGYRRVMLKLGGEMFGGGAVGVDPDVVQTVARQITEVVRTGVQVSVVIGGGNFFRGAELQQRGMDRDRADYMAMLGTVMNCLALQDFLEKQGIDTRVQTAITMGQVAEAYIPRRAERHLEKGRVVIFAAGVGMPYFSTDTAAAQRALEIGCEVVLMAKAVDGVYTADPKKDPTATMYHHITHREVLERGLKVADATAFSLCMDNNMPILVFNLLTEGNIARAVRGEKIGTLVSTP
>CP025990|4572796:4616063|4606563_4606953_+|AUS80160.1|DBSCAN-SWA
MPADSPRPRLVLGAAALDVTLVVVFAALGRREHERGGGIVGVLDTAWPFLVGLLLGWLLVRAWRAPTRPLHGLGVWLATLVGGLAIRALVLHWPPLSFALVAAGFLAACLVGWRLVAWWVSARASARAA
>CP025990|4572796:4616063|4583266_4584100_+|AUS80142.1|DBSCAN-SWA
MAVVTMKQLLDSGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQQTLTYIDRAFEFIRETVAHGGTILFVGTKKQAQEAISEQALRVGMPYVNQRWLGGMLTNFSTVHKRLQRLKELESMEQTGGFEGRTKKEILMLTREKDKLERTLGGIRDMAKVPSAVWIVDTKKEHIAVGEARKLGIPVVAVLDTNCDPDEVDYPIPGNDDAIRSAALLTRVVADGVAQGLMARSGRGNAPEGQEKPEPGVANDEPLAEWEQELLAGAASEGEKQGSEQPAQA
>CP025990|4572796:4616063|4577276_4577636_+|AUS80137.1|DBSCAN-SWA
MNTLDALDAQSLRSDIPAFRPGDTLKVHVRVIEGSRERVQVFQGAVIRRQGGGIRETFTVRKVSFGVGVERTFPVHSPNIAKIEVATRGDVRRAKLYYLRELRGKAAKIKEKRETPTAS
>CP025990|4572796:4616063|4610619_4611153_-|AUS81885.1|DBSCAN-SWA
MGLDRPVAPDPYRLLPEVGSFTVTSSDIRHGETLPDAQVAAHGDTSPQLSWRGFPEATRSFVVTCFDPDAPTPSGFWHWGVVNLPVDVTDLPTGAGASDDTLPAGAFHVRNDLGGHGFTGAAPPPGDHPHRYYFVVHAVDVPRLEVDGEASLAVVSFNLAFHTLARAELTATYATSG
>CP025990|4572796:4616063|4588370_4589462_-|AUS80147.1|DBSCAN-SWA
MTTGAFAAARAFDPARLTMARRLLGLSKRELAEWIGRPAALLSRFELGQSRPDVTVLSRCAQVMELPVGFFAAGRPQLRLDTTNAHFRSLRATTATQRLQALAQVELLWEVLSRLEDLIELPAVDLAPAATGSDPARAARAVRRGWDVPSGPVPHLVRTLEARGVAVARLVIPDNKNIDAFSSAKGGRPIIALTDRGNPLRQRFSVAHELGHLLLHPEPAPGNPRHEAEANAFAAELLMPATEIGDLLPVEPEPASLRDLGHRYGVSMAALAVRGRTLGFYSDTTYREVMVELSRLGLRTDEPVSEVFPGEEPTLLRTATEMAADQGVGLAELAARIEVTPAIIRRLLGIPDPRPHLRLVTSP
>CP025990|4572796:4616063|4593316_4594630_+|AUS80151.1|DBSCAN-SWA
MSEDPRETPALDHRVPDASGPPAVELRGVTRTYTDQVAVRDLSLRVGEGEFFSVLGPSGSGKTTLLRMVAGFEDPDGGAILLGGRDVVGVPAHRRDVNTVFQSYALFPHLSVWDNVAYGLRRLGLRRAELRARVGDYLDLVQLAGYGRRRPHQLSGGQQQRVAIARALARRPRVLLLDEPLAALDAQLRAQLRVELTRIQREVGTTFLYVTHDQEEALVLSHRLAVLRAGRVEQVGTPADVYERPVSRFVAEFIRSSTTGGSNVLEGTVRTVTGAGNAALVEVSVGEGAVLAELPPGRALRRGQPVAVAVRPEKARLYSAEDDGPPPGWSRVPVRPRDTVYTGAATEHLVEVVGDPGATPLTVFTQNTRRAGETGPGGGPVLVGWEPRFSVLLADEPGRGDGGAEPGGRARPTAADGDPTPGSAPTPVGATSRADVS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUS81876.1|4572796_4573576_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AUS80133.1|4573713_4574622_+|protease	CPBP family intramembrane metalloprotease domain-containing protein	NA	NA	NA	NA
AUS80134.1|4574869_4575322_+	30S ribosomal protein S16	NA	NA	NA	NA
AUS80135.1|4575318_4575558_+	KH domain-containing protein	NA	NA	NA	NA
AUS80136.1|4575571_4576120_+	ribosome maturation factor RimM	NA	NA	NA	NA
AUS81877.1|4576294_4577113_+|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
AUS80137.1|4577276_4577636_+	50S ribosomal protein L19	NA	NA	NA	NA
AUS80138.1|4577796_4578651_+	signal peptidase I	NA	NA	NA	NA
AUS81878.1|4578707_4579400_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.3e-16	31.9
AUS80139.1|4579486_4579813_+	DUF2469 domain-containing protein	NA	NA	NA	NA
AUS80140.1|4580313_4581258_+	tyrosine recombinase XerC	A0A1B3B212	Gordonia_phage	8.7e-12	30.6
AUS80141.1|4581469_4582222_+	FliA/WhiG family RNA polymerase sigma factor	A0A1I9S6C3	Bacillus_phage	9.7e-06	27.6
AUS80142.1|4583266_4584100_+	30S ribosomal protein S2	NA	NA	NA	NA
AUS80143.1|4584258_4585074_+	elongation factor Ts	NA	NA	NA	NA
AUS80144.1|4585178_4585916_+	UMP kinase	NA	NA	NA	NA
AUS80145.1|4586047_4586605_+	ribosome recycling factor	NA	NA	NA	NA
AUS80146.1|4586613_4587531_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
AUS81879.1|4587578_4588340_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AUS80147.1|4588370_4589462_-	ImmA/IrrE family metallo-endopeptidase	A0A0U4JD08	Gordonia_phage	1.0e-24	31.2
AUS80148.1|4589625_4590336_-	hypothetical protein	NA	NA	NA	NA
AUS80149.1|4590513_4591620_+	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
AUS81880.1|4592013_4592499_-	carbonic anhydrase	NA	NA	NA	NA
AUS80150.1|4592747_4592996_-	DUF2631 domain-containing protein	NA	NA	NA	NA
AUS80151.1|4593316_4594630_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.5e-22	29.0
AUS80152.1|4594712_4595873_+	spermidine/putrescine ABC transporter substrate-binding protein	NA	NA	NA	NA
AUS81881.1|4596010_4596835_+	ABC transporter permease	NA	NA	NA	NA
AUS81882.1|4596888_4597662_+	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
AUS80153.1|4597685_4597952_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
AUS81883.1|4598246_4599491_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
AUS80154.1|4599503_4600715_+|protease	zinc metalloprotease	NA	NA	NA	NA
AUS80155.1|4600903_4602061_+	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
AUS80156.1|4602189_4603026_+	DUF4081 domain-containing protein	NA	NA	NA	NA
AUS81884.1|4603197_4605045_+	penicillin-binding protein	NA	NA	NA	NA
AUS80157.1|4605062_4605275_-	hypothetical protein	NA	NA	NA	NA
AUS80158.1|4605274_4605544_-	hypothetical protein	NA	NA	NA	NA
AUS80159.1|4605536_4606523_-	hypothetical protein	NA	NA	NA	NA
AUS80160.1|4606563_4606953_+	DUF3054 domain-containing protein	NA	NA	NA	NA
AUS80161.1|4606963_4607821_+	type I methionyl aminopeptidase	NA	NA	NA	NA
AUS80162.1|4607848_4609237_-	mycothione reductase	A0A2K5B2C5	Erysipelothrix_phage	6.3e-43	26.6
AUS80163.1|4609284_4610442_-	VanZ family protein	NA	NA	NA	NA
AUS81885.1|4610619_4611153_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AUS80164.1|4611465_4611906_+	polyketide cyclase	NA	NA	NA	NA
AUS80165.1|4612186_4613299_+|protease	Zn-dependent protease	NA	NA	NA	NA
AUS80166.1|4613491_4614352_+|protease	serine protease	I6WTR7	Cotesia_sesamiae_Mombasa_bracovirus	1.8e-16	32.4
AUS80167.1|4614371_4615025_-	LysE family translocator	NA	NA	NA	NA
AUS80168.1|4615208_4616063_+|protease	serine protease	Q6JPG5	Neodiprion_lecontei_nucleopolyhedrovirus	7.1e-29	32.9