CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026005	Brucella melitensis strain CIIMS-PH-3 chromosome 1, complete sequence	0 crisprs	csa3,WYL	0	0	3	0
CP026006	Brucella melitensis strain CIIMS-PH-3 chromosome 2, complete sequence	0 crisprs	DEDDh,csa3,cas3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

453127 : 463150

Brucella_phage(37.5%)

integrase,transposase

attL 448125:448165|attR 463228:463268

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
448125:448165	attL	NA	NA	NA	NA
AUS46283.1\|453127_454579_-	hypothetical protein	A0A141GEY6	Brucella_phage	1.1e-135	56.9
AUS46284.1\|454990_455683_-	hypothetical protein	A0A141GEY5	Brucella_phage	4.4e-106	97.5
AUS46285.1\|455683_456443_-\|transposase	IS5/IS1182 family transposase	A0A0N9SJT9	Paenibacillus_phage	7.9e-16	40.2
AUS46286.1\|457283_457529_+	hypothetical protein	NA	NA	NA	NA
AUS46287.1\|457528_457843_+	hypothetical protein	K4NZP3	Burkholderia_phage	2.0e-05	42.1
AUS46288.1\|457958_458192_-	hypothetical protein	NA	NA	NA	NA
AUS46289.1\|458190_458361_+	DUF1508 domain-containing protein	A0A2P1N580	Mycobacterium_phage	3.1e-05	45.1
AUS47794.1\|458708_459419_-	porin family protein	O11861	Bartonella_henselae_phage	5.1e-41	36.8
AUS46290.1\|459764_460241_-	hypothetical protein	NA	NA	NA	NA
AUS46291.1\|460263_460539_-	hypothetical protein	NA	NA	NA	NA
AUS46292.1\|460535_460766_-	hypothetical protein	NA	NA	NA	NA
AUS46293.1\|460762_461467_-	hypothetical protein	A0A076GD06	Sinorhizobium_phage	4.5e-05	46.8
AUS46294.1\|461516_461720_+	hypothetical protein	NA	NA	NA	NA
AUS46295.1\|461716_461932_+	hypothetical protein	NA	NA	NA	NA
AUS46296.1\|461934_462138_+	hypothetical protein	NA	NA	NA	NA
AUS46297.1\|462124_463150_+\|integrase	site-specific integrase	A0A141GEZ3	Brucella_phage	5.6e-49	36.7
463228:463268	attR	NA	NA	NA	NA

DBSCAN-SWA_2

532162 : 544090

uncultured_Mediterranean_phage(90.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUS46355.1\|532162_534490_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	6.2e-51	43.5
AUS46356.1\|534609_534951_-	immunogenic membrane protein YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	9.1e-12	40.2
AUS46357.1\|535110_535977_+	DUF815 domain-containing protein	NA	NA	NA	NA
AUS46358.1\|536025_537324_-	LysM peptidoglycan-binding domain-containing protein	Q8SBN9	Clostridium_phage	1.0e-18	41.1
AUS46359.1\|537372_537558_-	hypothetical protein	NA	NA	NA	NA
AUS46360.1\|537702_538371_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	6.6e-14	38.5
AUS46361.1\|538367_539135_-	5'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.0e-39	40.2
AUS47801.1\|539283_540567_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.6e-104	47.2
AUS46362.1\|540643_541468_-	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	9.8e-44	41.1
AUS46363.1\|541464_542046_-	twin-arginine translocase subunit TatB	NA	NA	NA	NA
AUS46364.1\|542156_542375_-	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	1.5e-07	65.1
AUS46365.1\|542520_543246_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.5e-43	45.7
AUS46366.1\|543238_544090_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.4e-31	33.5

DBSCAN-SWA_3

768746 : 815143

Mesorhizobium_phage(14.29%)

integrase,tail,head,protease

attL 759552:759566|attR 772989:773003

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
759552:759566	attL	NA	NA	NA	NA
AUS46581.1\|768746_769673_+\|integrase	site-specific integrase	A0A076YL28	Mesorhizobium_phage	5.9e-29	31.6
AUS46582.1\|770035_771169_+	pyridoxal phosphate-dependent aminotransferase	A0A1X7QHI1	Faustovirus	2.4e-16	24.2
AUS47818.1\|771186_771561_+	DUF423 domain-containing protein	NA	NA	NA	NA
AUS46583.1\|771605_772256_-	antifreeze protein	NA	NA	NA	NA
AUS47819.1\|772911_773682_+	YitT family protein	NA	NA	NA	NA
772989:773003	attR	NA	NA	NA	NA
AUS46584.1\|773741_773999_-	sel1 repeat family protein	NA	NA	NA	NA
AUS46585.1\|774268_774508_+	hypothetical protein	NA	NA	NA	NA
AUS46586.1\|774504_774852_+	DUF2147 domain-containing protein	NA	NA	NA	NA
AUS46587.1\|774910_775621_-	thiol:disulfide oxidoreductase	NA	NA	NA	NA
AUS46588.1\|776187_777690_+	AMP nucleosidase	NA	NA	NA	NA
AUS46589.1\|777742_778819_+	AP endonuclease	NA	NA	NA	NA
AUS46590.1\|778934_780626_-	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
AUS46591.1\|781014_781887_+	uracil-DNA glycosylase	NA	NA	NA	NA
AUS46592.1\|783308_784268_-	EamA/RhaT family transporter	NA	NA	NA	NA
AUS46593.1\|784493_787145_+	aminopeptidase N	NA	NA	NA	NA
AUS46594.1\|787535_789887_+	PAS domain-containing sensor histidine kinase	A0A1V0SGX0	Hokovirus	6.3e-27	34.8
AUS46595.1\|790157_792269_+	hypothetical protein	NA	NA	NA	NA
AUS46596.1\|792313_795265_-	[glutamate--ammonia-ligase] adenylyltransferase	NA	NA	NA	NA
AUS46597.1\|795387_796794_-	sensor histidine kinase	NA	NA	NA	NA
AUS46598.1\|796790_797498_-	DNA-binding response regulator	NA	NA	NA	NA
AUS46599.1\|797591_799133_-\|protease	DegP-like serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	1.7e-28	29.8
AUS46600.1\|799274_799751_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
AUS46601.1\|799747_801739_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
AUS46602.1\|801758_802256_-	cytochrome c-type biogenesis protein CcmE	NA	NA	NA	NA
AUS46603.1\|802252_803392_-	c-type cytochrome biogenesis protein CcmI	NA	NA	NA	NA
AUS47820.1\|803492_803945_-	hypothetical protein	NA	NA	NA	NA
AUS46604.1\|804038_805349_-	ATP-binding protein	NA	NA	NA	NA
AUS46605.1\|805423_806113_-	DNA-binding response regulator	NA	NA	NA	NA
AUS47821.1\|806191_806488_-	hypothetical protein	NA	NA	NA	NA
AUS46606.1\|806649_806856_-	hypothetical protein	NA	NA	NA	NA
AUS46607.1\|810780_811215_-	peptidase P60	NA	NA	NA	NA
AUS46608.1\|811211_812087_-	DUF2163 domain-containing protein	A0A0K1Y6Z2	Rhodobacter_phage	4.5e-47	38.9
AUS46609.1\|812083_812716_-	TIGR02217 family protein	A0A0B5A2K3	Paracoccus_phage	2.9e-48	47.6
AUS46610.1\|812718_813264_-\|tail	phage tail protein	A0A0S2SYD9	Pseudomonas_phage	2.8e-07	46.4
AUS46611.1\|813268_813439_-\|tail	phage tail assembly chaperone	NA	NA	NA	NA
AUS46612.1\|813482_813824_-	gene transfer agent family protein	NA	NA	NA	NA
AUS46613.1\|813820_814234_-\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
AUS46614.1\|814274_814682_-	DUF3168 domain-containing protein	NA	NA	NA	NA
AUS46615.1\|814804_815143_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage