CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP025626	Escherichia coli strain SCEC020007 plasmid pNDM5_020007, complete sequence	0 crisprs	RT	0	2
CP025625	Escherichia coli strain SCEC020007 plasmid pBOKZ_020007, complete sequence	0 crisprs	NA	0	0
CP025627	Escherichia coli strain SCEC020007 chromosome, complete genome	8 crisprs	csa3,PD-DExK,RT,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4	15	8

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1796 : 41664

Macacine_betaherpesvirus(28.57%)

integrase,transposase,protease

attL 13550:13609|attR 48055:48203

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN45385.1\|1796_2450_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AUN45386.1\|2669_3134_+	mRNA interferase PemK	NA	NA	NA	NA
AUN45387.1\|3130_3235_+	hypothetical protein	NA	NA	NA	NA
AUN45388.1\|3270_6168_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	4.2e-182	37.8
AUN45389.1\|6262_6868_+	DNA resolvase	A0A1S5Y2X8	uncultured_archaeal_virus	9.4e-20	35.3
AUN45523.1\|7644_8037_+	cysteine hydrolase	NA	NA	NA	NA
AUN45390.1\|8174_9059_+	EamA family transporter	NA	NA	NA	NA
AUN45391.1\|9090_10290_-	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
AUN45392.1\|10368_11046_+	TetR family transcriptional regulator	NA	NA	NA	NA
AUN45524.1\|11077_11320_-	relaxase	NA	NA	NA	NA
AUN45393.1\|12941_13646_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
13550:13609	attL	NA	NA	NA	NA
AUN45394.1\|13679_14567_-\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	9.2e-56	42.2
AUN45525.1\|14724_15198_+	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
AUN45395.1\|15328_16117_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
AUN45396.1\|16322_16670_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
AUN45397.1\|16663_17503_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AUN45398.1\|17907_19449_+\|transposase	IS91 family transposase	NA	NA	NA	NA
AUN45399.1\|19761_20793_+	twin-arginine translocation (TAT) pathway signal sequence domain protein	NA	NA	NA	NA
AUN45400.1\|20803_21442_-	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AUN45401.1\|21446_21812_-	bleomycin binding protein Ble-MBL	NA	NA	NA	NA
AUN45402.1\|21815_22628_-	subclass B1 metallo-beta-lactamase NDM-5	NA	NA	NA	NA
AUN45403.1\|23186_23891_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN45404.1\|25497_26770_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.8e-174	98.0
AUN45405.1\|26791_27325_+	hypothetical protein	NA	NA	NA	NA
AUN45526.1\|27792_27930_-	single-stranded DNA-binding protein	NA	NA	NA	NA
AUN45406.1\|28074_28401_-	hypothetical protein	NA	NA	NA	NA
AUN45407.1\|28986_30654_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.7e-164	53.3
AUN45408.1\|30966_31158_-	hypothetical protein	NA	NA	NA	NA
AUN45409.1\|31154_31577_-	DUF1380 domain-containing protein	NA	NA	NA	NA
AUN45410.1\|31623_32049_-	antirestriction protein	NA	NA	NA	NA
AUN45411.1\|32462_33233_-	hypothetical protein	NA	NA	NA	NA
AUN45412.1\|33277_33712_-	DUF1380 domain-containing protein	NA	NA	NA	NA
AUN45413.1\|33725_33947_-	hypothetical protein	NA	NA	NA	NA
AUN45414.1\|33947_34631_-	DNA methylase	A0A2I7RE86	Vibrio_phage	1.1e-29	36.0
AUN45527.1\|35015_35918_-	DUF1281 domain-containing protein	NA	NA	NA	NA
AUN45415.1\|35955_36228_-	hypothetical protein	NA	NA	NA	NA
AUN45416.1\|36655_37627_-	protein SopB	I3WF22	Macacine_betaherpesvirus	4.8e-175	100.0
AUN45417.1\|37626_38793_-	protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	7.0e-229	100.0
AUN45418.1\|39380_40136_-	replication initiation protein	I3WF20	Macacine_betaherpesvirus	3.8e-143	100.0
AUN45419.1\|40857_41664_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.8e-57	100.0
48055:48203	attR	NA	NA	NA	NA

DBSCAN-SWA_2

61838 : 101811

Escherichia_phage(31.25%)

integrase,transposase

attL 61775:61834|attR 91684:92504

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
61775:61834	attL	NA	NA	NA	NA
AUN45440.1\|61838_62543_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN45441.1\|62488_62668_-	hypothetical protein	NA	NA	NA	NA
AUN45442.1\|63046_64060_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AUN45443.1\|64204_64702_+	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
AUN45444.1\|65109_65901_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
AUN45445.1\|66064_66412_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
AUN45446.1\|66405_67245_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AUN45447.1\|67174_67354_-	hypothetical protein	NA	NA	NA	NA
AUN45448.1\|67372_67576_+	hypothetical protein	NA	NA	NA	NA
AUN45449.1\|67731_68937_+	chromate transporter	NA	NA	NA	NA
AUN45450.1\|68947_69253_+	PadR family transcriptional regulator	NA	NA	NA	NA
AUN45451.1\|69268_69451_-	resolvase	NA	NA	NA	NA
AUN45529.1\|69479_70244_+\|transposase	IS6 family transposase IS6100	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AUN45452.1\|70434_70791_-	hypothetical protein	NA	NA	NA	NA
AUN45453.1\|70736_71321_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AUN45454.1\|71320_72559_-	MFS transporter	NA	NA	NA	NA
AUN45455.1\|72555_73461_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
AUN45456.1\|73582_74287_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN45457.1\|74845_75658_+	subclass B1 metallo-beta-lactamase NDM-5	NA	NA	NA	NA
AUN45458.1\|75661_76027_+	bleomycin binding protein Ble-MBL	NA	NA	NA	NA
AUN45459.1\|76031_76670_+	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AUN45460.1\|76680_77712_-	twin-arginine translocation (TAT) pathway signal sequence domain protein	NA	NA	NA	NA
AUN45461.1\|78024_79566_-\|transposase	IS91 family transposase	NA	NA	NA	NA
AUN45462.1\|79970_80810_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AUN45463.1\|80803_81151_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
AUN45464.1\|81356_82145_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
AUN45530.1\|82275_82749_-	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
AUN45465.1\|82906_83794_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	9.2e-56	42.2
AUN45466.1\|83827_84532_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN45467.1\|87213_87771_+	recombinase	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
AUN45468.1\|87953_88814_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AUN45469.1\|88983_89739_+	16S rRNA (guanine(1405)-N(7))-methyltransferase RmtB1	NA	NA	NA	NA
AUN45470.1\|89819_90368_-	potassium/proton antiporter	NA	NA	NA	NA
AUN45471.1\|90388_90781_+	molecular chaperone GroEL	A0A2I7SAK5	Vibrio_phage	8.5e-22	58.1
AUN45472.1\|90974_91679_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN45473.1\|93014_94292_+	MFS transporter	NA	NA	NA	NA
91684:92504	attR	NA	NA	NA	NA
AUN45474.1\|94291_95722_+	glycosyl hydrolase family 32	F8WPR5	Bacillus_phage	1.2e-28	24.5
AUN45475.1\|95916_97311_+	porin	NA	NA	NA	NA
AUN45476.1\|97310_97490_+	hypothetical protein	NA	NA	NA	NA
AUN45477.1\|98430_99054_+	ion transporter	NA	NA	NA	NA
AUN45478.1\|100441_101811_-\|transposase	IS3-like element IS150 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.3e-112	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP025627

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CRISPR-Cas detection and classification

Crispr_ID: CP025627_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_1

1087234-1087568

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACC	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACC	CRT

5 spacers

The CRISPR arrays of CP025627_1

>merge|CP025627|1|1087234-1087568|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCTGTGTTTGCGGCATTAACGCTCACCAGTATTTCGTGTTCCCCGCGCCAGCGGGGATAAACCGACGTGGTCATGGGTGCTGCTGTTGCAGAGCCAGTGTTCCCCGCGCCAGCGGGGATAAACCGAGCAGATACACGGCTTTGTATTCCGTGCGCCCGTGTTCCCCGCGCCAGCGGGGATAAACCGAATAGCAATAGTCCATAGATTTGCGAAAACAGGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACCAC

>CP025627|1|1|1087234-1087566|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGTATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GACGTGGTCATGGGTGCTGCTGTTGCAGAGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

>CP025627|1|1|1087234-1087568|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCTG	TGTTTGCGGCATTAACGCTCACCAGTATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	CGTGGTCATGGGTGCTGCTGTTGCAGAGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	GCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	ATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCGG	AGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCAC

>CP025627|1|1|1087234-1087566|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGTATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GACGTGGTCATGGGTGCTGCTGTTGCAGAGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN46560.1\|1097400_1097661_-\|ferredoxin-like-protein-YgcO	unknown	unknown	gnl\|CDD\|225289
CP025627.1\|AUN46547.1\|1081974_1083612_+\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
CP025627.1\|AUN46555.1\|1092161_1093616_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
CP025627.1\|AUN46554.1\|1091306_1092092_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|187605
CP025627.1\|AUN46552.1\|1088205_1089684_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
CP025627.1\|AUN46561.1\|1097651_1098923_-\|electron-transfer-flavoprotein-quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
CP025627.1\|AUN46553.1\|1089710_1090988_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
CP025627.1\|AUN46548.1\|1083699_1084998_+\|enolase	unknown	unknown	gnl\|CDD\|234617
CP025627.1\|AUN46544.1\|1080301_1080550_+\|antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
CP025627.1\|AUN46558.1\|1095800_1096661_+\|electron-transfer-flavoprotein	unknown	unknown	gnl\|CDD\|224936
CP025627.1\|AUN46545.1\|1080549_1080885_+\|mRNA-interferase-MazF	unknown	unknown	gnl\|CDD\|182138
CP025627.1\|AUN46546.1\|1080955_1081747_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
CP025627.1\|AUN46556.1\|1093709_1095047_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
CP025627.1\|AUN46551.1\|1086222_1086894_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
CP025627.1\|AUN46557.1\|1095024_1095804_+\|electron-transfer-flavoprotein	unknown	unknown	gnl\|CDD\|224997
CP025627.1\|AUN46549.1\|1085057_1085930_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224429
CP025627.1\|AUN46543.1\|1077989_1080224_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
CP025627.1\|AUN46550.1\|1085943_1086084_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN46559.1\|1096808_1097384_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
CP025627.1\|AUN46542.1\|1076640_1077942_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN46560.1\|1097400_1097661_-\|ferredoxin-like-protein-YgcO	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	7.43419e-42
CP025627.1\|AUN46547.1\|1081974_1083612_+\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP025627.1\|AUN46555.1\|1092161_1093616_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.41244e-83
CP025627.1\|AUN46554.1\|1091306_1092092_+\|oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.96451e-139
CP025627.1\|AUN46552.1\|1088205_1089684_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	4.82999e-110
CP025627.1\|AUN46561.1\|1097651_1098923_-\|electron-transfer-flavoprotein-quinone-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	5.03655e-125
CP025627.1\|AUN46548.1\|1083699_1084998_+\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP025627.1\|AUN46544.1\|1080301_1080550_+\|antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
CP025627.1\|AUN46558.1\|1095800_1096661_+\|electron-transfer-flavoprotein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	7.42017e-90
CP025627.1\|AUN46545.1\|1080549_1080885_+\|mRNA-interferase-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
CP025627.1\|AUN46546.1\|1080955_1081747_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
CP025627.1\|AUN46556.1\|1093709_1095047_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
CP025627.1\|AUN46551.1\|1086222_1086894_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
CP025627.1\|AUN46557.1\|1095024_1095804_+\|electron-transfer-flavoprotein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
CP025627.1\|AUN46549.1\|1085057_1085930_-\|hypothetical-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.49372e-99
CP025627.1\|AUN46543.1\|1077989_1080224_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
CP025627.1\|AUN46553.1\|1089710_1090988_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.60446e-29
CP025627.1\|AUN46559.1\|1096808_1097384_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
CP025627.1\|AUN46542.1\|1076640_1077942_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0

>CP025627.1|AUN46551.1|1086222_1086894_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>CP025627.1|AUN46550.1|1085943_1086084_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNEYKITDAAVNLFIQI
>CP025627.1|AUN46549.1|1085057_1085930_-|hypothetical-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYAIRVFDNWRLGDAKRNDGILIVVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVCISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASGRW
>CP025627.1|AUN46548.1|1083699_1084998_+|enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP025627.1|AUN46547.1|1081974_1083612_+|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>CP025627.1|AUN46546.1|1080955_1081747_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>CP025627.1|AUN46545.1|1080549_1080885_+|mRNA-interferase-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>CP025627.1|AUN46544.1|1080301_1080550_+|antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>CP025627.1|AUN46543.1|1077989_1080224_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>CP025627.1|AUN46542.1|1076640_1077942_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>CP025627.1|AUN46552.1|1088205_1089684_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEVLGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDNMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>CP025627.1|AUN46553.1|1089710_1090988_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLTLTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALGMVIVFTFLLFQKIRTADSAPAMASSK
>CP025627.1|AUN46554.1|1091306_1092092_+|oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>CP025627.1|AUN46555.1|1092161_1093616_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKVTGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNIVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>CP025627.1|AUN46556.1|1093709_1095047_+|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>CP025627.1|AUN46557.1|1095024_1095804_+|electron-transfer-flavoprotein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>CP025627.1|AUN46558.1|1095800_1096661_+|electron-transfer-flavoprotein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>CP025627.1|AUN46559.1|1096808_1097384_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>CP025627.1|AUN46560.1|1097400_1097661_-|ferredoxin-like-protein-YgcO
MSVARNLWRVADAPHIVPADSVERQTAERLINACPAGLFSLTPEGNLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>CP025627.1|AUN46561.1|1097651_1098923_-|electron-transfer-flavoprotein-quinone-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGVTTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: CP025627_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_2

1113117-1113818

TypeI-E

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

11 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of CP025627_2

>merge|CP025627|2|1113117-1113818|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCGTTTGGATCGGGTCTGGAATTTCTGAGCGGTCGCGAGTTCCCCGCGCCAGCGGGGATAAACCGCGAATCGCGCATACCCTGCGCGTCGCCGCCTGCGAGTTCCCCGCGCCAGCGGGGATAAACCGTCAGCTTTATAAATCCGGAGATACGGAAACTAGAGTTCCCCGCGCCAGCGGGGATAAACCGGACTCACCCCGAAAGAGATTGCCAGCCAGCTTGAGTTCCCCGCGCCAGCGGGGATAAACCGCTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCAGAGTTCCCCGCGCCAGCGGGGATAAACCGCCCACCAGCGCGTTTTTTGCCGGGGCCATAGTGAGTTCCCCGCGCCAGCGGGGATAAACCGTTGAACTCACCACGATTGTTAATATGGACGATGAGTTCCCCGCGCCAGCGGGGATAAACCGGGGGGCGCATGACCGTAAACATTATCCCCCGGGAGTTCCCCGCGCCAGCGGGGATAAACCGGGAGTTCAGACATAGGTGGAATGATGGACTACGAGTTCCCCGCGTTAGCGGGGATAAACCGCCCGGTAGCCAGGTTTGCAACGCCTGAACCGAGAGTTCCCCGCGCCAGCAGGGATAAACCGGCAACGACGGTGAGATTTCACGCCTGACGCTGGTGTTCCCCGCATCAGCGGGGATAAACCG

>CP025627|2|2|1113117-1113574|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGGATCGGGTCTGGAATTTCTGAGCGGTCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCGCGCATACCCTGCGCGTCGCCGCCTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAGCTTTATAAATCCGGAGATACGGAAACTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCACCCCGAAAGAGATTGCCAGCCAGCTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCACCAGCGCGTTTTTTGCCGGGGCCATAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTGAACTCACCACGATTGTTAATATGGACGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG

>CP025627|2|2|1113117-1113818|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGGATCGGGTCTGGAATTTCTGAGCGGTCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCGCGCATACCCTGCGCGTCGCCGCCTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAGCTTTATAAATCCGGAGATACGGAAACTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCACCCCGAAAGAGATTGCCAGCCAGCTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCACCAGCGCGTTTTTTGCCGGGGCCATAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTGAACTCACCACGATTGTTAATATGGACGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGGCGCATGACCGTAAACATTATCCCCCGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGTTCAGACATAGGTGGAATGATGGACTAC
GAGTTCCCCGCGTTAGCGGGGATAAACCG	CCCGGTAGCCAGGTTTGCAACGCCTGAACCGA
GAGTTCCCCGCGCCAGCAGGGATAAACCG	GCAACGACGGTGAGATTTCACGCCTGACGCTG
GTGTTCCCCGCATCAGCGGGGATAAACCG

>CP025627|2|2|1113117-1113818|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGGATCGGGTCTGGAATTTCTGAGCGGTCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCGCGCATACCCTGCGCGTCGCCGCCTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAGCTTTATAAATCCGGAGATACGGAAACTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCACCCCGAAAGAGATTGCCAGCCAGCTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCACCAGCGCGTTTTTTGCCGGGGCCATAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTGAACTCACCACGATTGTTAATATGGACGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGGCGCATGACCGTAAACATTATCCCCCGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGTTCAGACATAGGTGGAATGATGGACTAC
GAGTTCCCCGCGTTAGCGGGGATAAACCG	CCCGGTAGCCAGGTTTGCAACGCCTGAACCGA
GAGTTCCCCGCGCCAGCAGGGATAAACCG	GCAACGACGGTGAGATTTCACGCCTGACGCTG
GTGTTCCCCGCATCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN49939.1\|1112726_1113011_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP025627.1\|AUN46579.1\|1119028_1119739_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP025627.1\|AUN46568.1\|1108942_1109425_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|187801
CP025627.1\|AUN46570.1\|1110531_1111206_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
CP025627.1\|AUN46576.1\|1117526_1118132_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP025627.1\|AUN46565.1\|1103267_1104002_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP025627.1\|AUN46572.1\|1111807_1112725_+\|subtype-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP025627.1\|AUN46575.1\|1116099_1117527_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235349
CP025627.1\|AUN46581.1\|1120214_1121264_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP025627.1\|AUN46577.1\|1118181_1118505_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371891
CP025627.1\|AUN46566.1\|1104360_1107027_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
CP025627.1\|AUN46567.1\|1107465_1108950_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|236613
CP025627.1\|AUN46569.1\|1109437_1110529_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
CP025627.1\|AUN46582.1\|1121244_1122006_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP025627.1\|AUN46564.1\|1101480_1103193_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
CP025627.1\|AUN46574.1\|1115189_1116098_+\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP025627.1\|AUN46571.1\|1111192_1111792_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
CP025627.1\|AUN46573.1\|1113900_1114938_-\|Zn-dependent-exopeptidase-M28	unknown	unknown	gnl\|CDD\|182299
CP025627.1\|AUN46578.1\|1118698_1119010_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP025627.1\|AUN46580.1\|1119738_1120218_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN49939.1\|1112726_1113011_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	4.76227e-62
CP025627.1\|AUN46579.1\|1119028_1119739_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
CP025627.1\|AUN46568.1\|1108942_1109425_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187801	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.76293e-33
CP025627.1\|AUN46570.1\|1110531_1111206_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	2.15381e-103
CP025627.1\|AUN46576.1\|1117526_1118132_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
CP025627.1\|AUN46565.1\|1103267_1104002_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	2.39575e-137
CP025627.1\|AUN46572.1\|1111807_1112725_+\|subtype-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.68794e-159
CP025627.1\|AUN46575.1\|1116099_1117527_+\|sulfate-adenylyltransferase	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP025627.1\|AUN46581.1\|1120214_1121264_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP025627.1\|AUN46577.1\|1118181_1118505_+\|hypothetical-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
CP025627.1\|AUN46566.1\|1104360_1107027_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	0
CP025627.1\|AUN46567.1\|1107465_1108950_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|236613	PRK09693, PRK09693, Cascade antiviral complex protein; Validated.	0
CP025627.1\|AUN46569.1\|1109437_1110529_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	5.43824e-154
CP025627.1\|AUN46582.1\|1121244_1122006_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
CP025627.1\|AUN46564.1\|1101480_1103193_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP025627.1\|AUN46574.1\|1115189_1116098_+\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP025627.1\|AUN46571.1\|1111192_1111792_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.81669e-101
CP025627.1\|AUN46573.1\|1113900_1114938_-\|Zn-dependent-exopeptidase-M28	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP025627.1\|AUN46578.1\|1118698_1119010_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
CP025627.1\|AUN46580.1\|1119738_1120218_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104

>CP025627.1|AUN49939.1|1112726_1113011_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMLVVVTENVPPRLRGRLAIWLLEVRAGVYVGDVSAKIREMIWEQIAGLAEEGNVVMAWATNTETGFEFQTFGLNRRTPVDLDGLRLVSFLPV
>CP025627.1|AUN46572.1|1111807_1112725_+|subtype-I-E-CRISPR-associated-endonuclease-Cas1
MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS
>CP025627.1|AUN46571.1|1111192_1111792_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQTVCFEGVLTINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
>CP025627.1|AUN46570.1|1110531_1111206_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
>CP025627.1|AUN46569.1|1109437_1110529_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGEA
>CP025627.1|AUN46568.1|1108942_1109425_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MADEIDAMALYRAWQQLDNGSCAQIRRVSEPDELRDIPAFYRLVQPFGWENPRHQQALLRMVFCLSAGKNVIRHQDKKSEQTTGISLGRALANSGRINERRIFQLIRADRTADMVQLRRLLTHAEPVLDWPLMARMLTWWGKRERQQLLEDFVLTTNKNA
>CP025627.1|AUN46567.1|1107465_1108950_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG
>CP025627.1|AUN46566.1|1104360_1107027_+|CRISPR-associated-helicase/endonuclease-Cas3
MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWDQSVVLQNTFCRNEMLSKQRVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLNGPSTQMCRKFNHGAAGLYWFNQDSLSEQSLGDFFSFFDAAPHPYESWFPWVEAVTGHHGFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCSSLLAGFCSLADWLGSWTTTNTFLFNEDAPSDINALRTYFQDRQQDASRVLELSGLVSNKRCYEGVHALLDNGYQPRQLQVLVDALPVAPGLTVIEAPTGSGKTETALAYAWKLIDQQIADSVIFALPTQATANAMLTRMEASASHLFSSPNLILAHGNSRFNHLFQSIKSRAITEQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLIVDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPVENNSAYPLINWRGVNGAQRFDLLAHPEQLPPRFSIQPEPIYLADMLPDLTMLERMIAAANAGAQACLICNLVDVAQVCYQRLKELNNTQVDIDLFHARFTLNDRREKENRVISNFGKNGKRNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEIPVATILLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEMDEPEWVGNGMDKFESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLPYVQTSSGKQLLDGQVYEDLSHEQQYEALALNRVNVPFTWKRSFSEVVDEDGLLWLEGKQNLDGWVWQGNSIVITYTGDEGMTRVIPANPK
>CP025627.1|AUN46565.1|1103267_1104002_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP025627.1|AUN46564.1|1101480_1103193_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKHESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>CP025627.1|AUN46573.1|1113900_1114938_-|Zn-dependent-exopeptidase-M28
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNHQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>CP025627.1|AUN46574.1|1115189_1116098_+|sulfate-adenylyltransferase-subunit-2
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP025627.1|AUN46575.1|1116099_1117527_+|sulfate-adenylyltransferase
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>CP025627.1|AUN46576.1|1117526_1118132_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>CP025627.1|AUN46577.1|1118181_1118505_+|hypothetical-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>CP025627.1|AUN46578.1|1118698_1119010_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>CP025627.1|AUN46579.1|1119028_1119739_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>CP025627.1|AUN46580.1|1119738_1120218_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>CP025627.1|AUN46581.1|1120214_1121264_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>CP025627.1|AUN46582.1|1121244_1122006_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: CP025627_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_3

1610668-1610785

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025627_3

>merge|CP025627|3|1610668-1610785|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>CP025627|3|3|1610668-1610785|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN47020.1\|1610804_1613090_-\|ribonucleoside-diphosphate-reductase-1-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
CP025627.1\|AUN47022.1\|1617665_1618388_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
CP025627.1\|AUN49961.1\|1609440_1610571_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	unknown	unknown	gnl\|CDD\|181647
CP025627.1\|AUN47029.1\|1630661_1631846_-\|acetyl-CoA-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
CP025627.1\|AUN47028.1\|1629811_1630588_+\|DUF2135-domain-containing-protein	unknown	unknown	gnl\|CDD\|227021
CP025627.1\|AUN47018.1\|1608482_1609133_+\|protein-InaA	unknown	unknown	gnl\|CDD\|182136
CP025627.1\|AUN47014.1\|1603679_1605308_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
CP025627.1\|AUN47025.1\|1622995_1623619_+\|DUF1175-domain-containing-protein	unknown	unknown	gnl\|CDD\|225774
CP025627.1\|AUN47017.1\|1608061_1608268_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182050
CP025627.1\|AUN47026.1\|1623552_1628157_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
CP025627.1\|AUN47012.1\|1601243_1602434_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
CP025627.1\|AUN47027.1\|1628157_1629807_+\|DUF2300-domain-containing-protein	unknown	unknown	gnl\|CDD\|227732
CP025627.1\|AUN47013.1\|1602430_1603690_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B	unknown	unknown	gnl\|CDD\|225617
CP025627.1\|AUN47016.1\|1606943_1608020_+\|glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
CP025627.1\|AUN47023.1\|1618534_1621162_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502
CP025627.1\|AUN47015.1\|1605580_1606939_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
CP025627.1\|AUN47024.1\|1621310_1622999_+\|DUF2138-domain-containing-protein	unknown	unknown	gnl\|CDD\|227030
CP025627.1\|AUN47021.1\|1613785_1617538_+\|AIDA-I-family-autotransporter-YfaL	unknown	unknown	gnl\|CDD\|182059
CP025627.1\|AUN47019.1\|1609186_1609441_-\|ferredoxin	unknown	unknown	gnl\|CDD\|182668
CP025627.1\|AUN47011.1\|1600151_1601051_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182167

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN47020.1\|1610804_1613090_-\|ribonucleoside-diphosphate-reductase-1-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
CP025627.1\|AUN47022.1\|1617665_1618388_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.65303e-171
CP025627.1\|AUN49961.1\|1609440_1610571_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
CP025627.1\|AUN47029.1\|1630661_1631846_-\|acetyl-CoA-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
CP025627.1\|AUN47028.1\|1629811_1630588_+\|DUF2135-domain-containing-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	4.17009e-153
CP025627.1\|AUN47018.1\|1608482_1609133_+\|protein-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	2.86156e-158
CP025627.1\|AUN47014.1\|1603679_1605308_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
CP025627.1\|AUN47025.1\|1622995_1623619_+\|DUF1175-domain-containing-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	7.99004e-141
CP025627.1\|AUN47017.1\|1608061_1608268_-\|hypothetical-protein	gnl\|CDD\|182050	PRK09729, PRK09729, hypothetical protein; Provisional.	1.13329e-36
CP025627.1\|AUN47026.1\|1623552_1628157_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
CP025627.1\|AUN47012.1\|1601243_1602434_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
CP025627.1\|AUN47027.1\|1628157_1629807_+\|DUF2300-domain-containing-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	8.04949e-127
CP025627.1\|AUN47013.1\|1602430_1603690_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
CP025627.1\|AUN47016.1\|1606943_1608020_+\|glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
CP025627.1\|AUN47023.1\|1618534_1621162_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
CP025627.1\|AUN47015.1\|1605580_1606939_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
CP025627.1\|AUN47024.1\|1621310_1622999_+\|DUF2138-domain-containing-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
CP025627.1\|AUN47021.1\|1613785_1617538_+\|AIDA-I-family-autotransporter-YfaL	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
CP025627.1\|AUN47019.1\|1609186_1609441_-\|ferredoxin	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
CP025627.1\|AUN47011.1\|1600151_1601051_-\|hypothetical-protein	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	0

>CP025627.1|AUN49961.1|1609440_1610571_-|ribonucleoside-diphosphate-reductase-1-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>CP025627.1|AUN47019.1|1609186_1609441_-|ferredoxin
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>CP025627.1|AUN47018.1|1608482_1609133_+|protein-InaA
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>CP025627.1|AUN47017.1|1608061_1608268_-|hypothetical-protein
MNFIRQGLGIALQPELTLKSIAGELCSVPLEPTFYRQISLLAKEKPVEGSPLFLLQMCMEQLVAIGKI
>CP025627.1|AUN47016.1|1606943_1608020_+|glycerophosphoryl-diester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDNLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMELNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTPDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>CP025627.1|AUN47015.1|1605580_1606939_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQERNGG
>CP025627.1|AUN47014.1|1603679_1605308_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>CP025627.1|AUN47013.1|1602430_1603690_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>CP025627.1|AUN47012.1|1601243_1602434_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>CP025627.1|AUN47011.1|1600151_1601051_-|hypothetical-protein
MTESTASSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCH
>CP025627.1|AUN47020.1|1610804_1613090_-|ribonucleoside-diphosphate-reductase-1-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>CP025627.1|AUN47021.1|1613785_1617538_+|AIDA-I-family-autotransporter-YfaL
MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>CP025627.1|AUN47022.1|1617665_1618388_-|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>CP025627.1|AUN47023.1|1618534_1621162_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>CP025627.1|AUN47024.1|1621310_1622999_+|DUF2138-domain-containing-protein
MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIAGDLLSGKKRWQASFGLEERTAEKTPVRQRIVVSARWLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGIAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>CP025627.1|AUN47025.1|1622995_1623619_+|DUF1175-domain-containing-protein
MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>CP025627.1|AUN47026.1|1623552_1628157_+|alpha-2-macroglobulin-family-protein
MDTQRFQSQFHWHLSFKFSGAIAACLSLSLVGTGLANADDSLPSSNYAPPAGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVKQFRYPLWQAKPFEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVIGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALAKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGENALILPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPALAGAWAKHKLTGGGEDWRWVGQGVPDILSFGDELSPQNVQVRWREPAKMAQQSNIPVTVERQLYRLIPGEEEMSFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>CP025627.1|AUN47027.1|1628157_1629807_+|DUF2300-domain-containing-protein
MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGVTKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAVNPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTWARTMTAWTQDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKMPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>CP025627.1|AUN47028.1|1629811_1630588_+|DUF2135-domain-containing-protein
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPIHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>CP025627.1|AUN47029.1|1630661_1631846_-|acetyl-CoA-acetyltransferase
MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN

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Crispr_ID: CP025627_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_4

2279182-2279305

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025627_4

>merge|CP025627|4|2279182-2279305|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>CP025627|4|4|2279182-2279305|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN47618.1\|2276187_2277000_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
CP025627.1\|AUN47616.1\|2274733_2275402_+\|thiosulfate-reductase-electron-transport-protein-PhsB	unknown	unknown	gnl\|CDD\|274451
CP025627.1\|AUN47627.1\|2286877_2287903_-\|PurR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|236739
CP025627.1\|AUN47624.1\|2283185_2284334_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
CP025627.1\|AUN47626.1\|2285948_2286881_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
CP025627.1\|AUN47621.1\|2279619_2280876_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
CP025627.1\|AUN47617.1\|2275398_2276184_+\|protein-PhsC	unknown	unknown	gnl\|CDD\|184968
CP025627.1\|AUN47622.1\|2280916_2282290_-\|multidrug-resistance-protein-MdtK	unknown	unknown	gnl\|CDD\|234981
CP025627.1\|AUN47623.1\|2282504_2283146_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
CP025627.1\|AUN47611.1\|2268636_2270049_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|181699
CP025627.1\|AUN47629.1\|2288201_2288291_+\|YnhF-family-membrane-protein	unknown	unknown	unknown
CP025627.1\|AUN47620.1\|2278741_2279047_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
CP025627.1\|AUN47612.1\|2270605_2270815_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
CP025627.1\|AUN47630.1\|2288456_2289626_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
CP025627.1\|AUN47614.1\|2271916_2274019_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
CP025627.1\|AUN47615.1\|2274022_2274670_+\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|182160
CP025627.1\|AUN47625.1\|2284624_2285836_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
CP025627.1\|AUN47613.1\|2271269_2271896_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182135
CP025627.1\|AUN47628.1\|2287890_2288115_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN47619.1\|2277011_2278616_-\|FAD/NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|182134

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN47618.1\|2276187_2277000_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.58482e-174
CP025627.1\|AUN47616.1\|2274733_2275402_+\|thiosulfate-reductase-electron-transport-protein-PhsB	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
CP025627.1\|AUN47627.1\|2286877_2287903_-\|PurR-family-transcriptional-regulator	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
CP025627.1\|AUN47624.1\|2283185_2284334_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
CP025627.1\|AUN47626.1\|2285948_2286881_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
CP025627.1\|AUN47621.1\|2279619_2280876_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
CP025627.1\|AUN47617.1\|2275398_2276184_+\|protein-PhsC	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.40835e-163
CP025627.1\|AUN47622.1\|2280916_2282290_-\|multidrug-resistance-protein-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
CP025627.1\|AUN47623.1\|2282504_2283146_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
CP025627.1\|AUN47611.1\|2268636_2270049_-\|pyruvate-kinase	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
CP025627.1\|AUN47620.1\|2278741_2279047_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
CP025627.1\|AUN47612.1\|2270605_2270815_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
CP025627.1\|AUN47630.1\|2288456_2289626_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
CP025627.1\|AUN47614.1\|2271916_2274019_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
CP025627.1\|AUN47615.1\|2274022_2274670_+\|ribonuclease-P-protein-component	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	3.717e-122
CP025627.1\|AUN47625.1\|2284624_2285836_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
CP025627.1\|AUN47613.1\|2271269_2271896_+\|hypothetical-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
CP025627.1\|AUN47619.1\|2277011_2278616_-\|FAD/NAD(P)-binding-domain-containing-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0

>CP025627.1|AUN47620.1|2278741_2279047_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>CP025627.1|AUN47619.1|2277011_2278616_-|FAD/NAD(P)-binding-domain-containing-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEDSHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>CP025627.1|AUN47618.1|2276187_2277000_+|hypothetical-protein
MIITQADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERPFCSQFARSDDHARIGCCEDNARITTAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>CP025627.1|AUN47617.1|2275398_2276184_+|protein-PhsC
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQTHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>CP025627.1|AUN47616.1|2274733_2275402_+|thiosulfate-reductase-electron-transport-protein-PhsB
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>CP025627.1|AUN47615.1|2274022_2274670_+|ribonuclease-P-protein-component
MGKMNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYLVAEEELSVLLESIKQNGDYADIACLTGSKDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>CP025627.1|AUN47614.1|2271916_2274019_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>CP025627.1|AUN47613.1|2271269_2271896_+|hypothetical-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>CP025627.1|AUN47612.1|2270605_2270815_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>CP025627.1|AUN47611.1|2268636_2270049_-|pyruvate-kinase
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>CP025627.1|AUN47621.1|2279619_2280876_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINLNGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>CP025627.1|AUN47622.1|2280916_2282290_-|multidrug-resistance-protein-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
>CP025627.1|AUN47623.1|2282504_2283146_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>CP025627.1|AUN47624.1|2283185_2284334_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>CP025627.1|AUN47625.1|2284624_2285836_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKLVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>CP025627.1|AUN47626.1|2285948_2286881_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>CP025627.1|AUN47627.1|2286877_2287903_-|PurR-family-transcriptional-regulator
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>CP025627.1|AUN47628.1|2287890_2288115_-|hypothetical-protein
MISVFTTSPFRQDRPKFHAYTICVLAIDPFLTLRVVFPAYRNTFVVRKVCKGKRLPCDFAGAEVRVWSEMEWQQ
>CP025627.1|AUN47629.1|2288201_2288291_+|YnhF-family-membrane-protein
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>CP025627.1|AUN47630.1|2288456_2289626_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS

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Crispr_ID: CP025627_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_6

3209633-3209777

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025627_6

>merge|CP025627|6|3209633-3209777|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>CP025627|6|6|3209633-3209777|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN48461.1\|3200017_3202039_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP025627.1\|AUN48476.1\|3217952_3219011_-\|molybdenum-import-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
CP025627.1\|AUN48472.1\|3213753_3214806_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
CP025627.1\|AUN48466.1\|3206307_3207597_+\|adenosylmethionine--8-amino-7-oxononanoate-aminotransferase-BioA	unknown	unknown	gnl\|CDD\|181189
CP025627.1\|AUN48469.1\|3208283_3209567_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|236709
CP025627.1\|AUN48465.1\|3205180_3206221_-\|biotin-synthase	unknown	unknown	gnl\|CDD\|185063
CP025627.1\|AUN48462.1\|3202617_3203295_-\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
CP025627.1\|AUN48470.1\|3209800_3212062_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
CP025627.1\|AUN48471.1\|3212244_3213678_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
CP025627.1\|AUN48479.1\|3220497_3220707_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN48474.1\|3215983_3216979_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
CP025627.1\|AUN48477.1\|3219013_3219703_-\|molybdenum-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181841
CP025627.1\|AUN48475.1\|3217133_3217952_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|182523
CP025627.1\|AUN48468.1\|3208046_3208226_+\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN48473.1\|3214989_3215943_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
CP025627.1\|AUN48464.1\|3204029_3205184_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
CP025627.1\|AUN48478.1\|3219702_3220476_-\|molybdate-binding-periplasmic-protein	unknown	unknown	gnl\|CDD\|182641
CP025627.1\|AUN48460.1\|3198917_3199826_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211689
CP025627.1\|AUN48467.1\|3207655_3208132_+\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
CP025627.1\|AUN48463.1\|3203287_3204043_-\|malonyl-[acyl-carrier-protein]-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN48461.1\|3200017_3202039_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP025627.1\|AUN48476.1\|3217952_3219011_-\|molybdenum-import-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
CP025627.1\|AUN48472.1\|3213753_3214806_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
CP025627.1\|AUN48466.1\|3206307_3207597_+\|adenosylmethionine--8-amino-7-oxononanoate-aminotransferase-BioA	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
CP025627.1\|AUN48469.1\|3208283_3209567_+\|acyl-CoA-thioesterase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
CP025627.1\|AUN48465.1\|3205180_3206221_-\|biotin-synthase	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
CP025627.1\|AUN48462.1\|3202617_3203295_-\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	1.13421e-109
CP025627.1\|AUN48470.1\|3209800_3212062_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
CP025627.1\|AUN48471.1\|3212244_3213678_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
CP025627.1\|AUN48474.1\|3215983_3216979_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
CP025627.1\|AUN48477.1\|3219013_3219703_-\|molybdenum-ABC-transporter-permease	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
CP025627.1\|AUN48475.1\|3217133_3217952_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
CP025627.1\|AUN48473.1\|3214989_3215943_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
CP025627.1\|AUN48464.1\|3204029_3205184_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
CP025627.1\|AUN48478.1\|3219702_3220476_-\|molybdate-binding-periplasmic-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
CP025627.1\|AUN48460.1\|3198917_3199826_+\|hypothetical-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.22556e-139
CP025627.1\|AUN48467.1\|3207655_3208132_+\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.08182e-118
CP025627.1\|AUN48463.1\|3203287_3204043_-\|malonyl-[acyl-carrier-protein]-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	7.9121e-172

>CP025627.1|AUN48469.1|3208283_3209567_+|acyl-CoA-thioesterase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>CP025627.1|AUN48468.1|3208046_3208226_+|hypothetical-protein
MKVPAARWSGLTFISTLWQAPRLLRCLVNHSARWRNAIWYHLKVLKTTFCLFTFPFRSS
>CP025627.1|AUN48467.1|3207655_3208132_+|kinase-inhibitor
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>CP025627.1|AUN48466.1|3206307_3207597_+|adenosylmethionine--8-amino-7-oxononanoate-aminotransferase-BioA
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>CP025627.1|AUN48465.1|3205180_3206221_-|biotin-synthase
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>CP025627.1|AUN48464.1|3204029_3205184_-|8-amino-7-oxononanoate-synthase
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>CP025627.1|AUN48463.1|3203287_3204043_-|malonyl-[acyl-carrier-protein]-O-methyltransferase-BioC
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
>CP025627.1|AUN48462.1|3202617_3203295_-|ATP-dependent-dethiobiotin-synthetase-BioD
MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLHNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL
>CP025627.1|AUN48461.1|3200017_3202039_-|excinuclease-ABC-subunit-B
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>CP025627.1|AUN48460.1|3198917_3199826_+|hypothetical-protein
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHNALEKALQALG
>CP025627.1|AUN48470.1|3209800_3212062_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVSRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>CP025627.1|AUN48471.1|3212244_3213678_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>CP025627.1|AUN48472.1|3213753_3214806_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>CP025627.1|AUN48473.1|3214989_3215943_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>CP025627.1|AUN48474.1|3215983_3216979_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>CP025627.1|AUN48475.1|3217133_3217952_+|Cof-type-HAD-IIB-family-hydrolase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDSFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>CP025627.1|AUN48476.1|3217952_3219011_-|molybdenum-import-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>CP025627.1|AUN48477.1|3219013_3219703_-|molybdenum-ABC-transporter-permease
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>CP025627.1|AUN48478.1|3219702_3220476_-|molybdate-binding-periplasmic-protein
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQFKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASVQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGIKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK
>CP025627.1|AUN48479.1|3220497_3220707_-|hypothetical-protein
MVKYSTSFLVLVKKTSPDKIIDSLNARLVGHFLFLNFLLFLPIFFLIYLTKVSNNCWENSELVVILSPT

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Crispr_ID: CP025627_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_7

3454111-3454207

Orphan

Consensus_repeat	Method
TTGTAGGCCTGATAAGATGCGTCAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025627_7

>merge|CP025627|7|3454111-3454207|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGCATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGGTTGTAGGCCTGATAAGACGCGTCAAGC

>CP025627|7|7|3454111-3454207|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGC	ATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGG
TTGTAGGCCTGATAAGACGCGTCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN48691.1\|3455956_3457216_-\|DUF1116-domain-containing-protein	unknown	unknown	gnl\|CDD\|377673
CP025627.1\|AUN48686.1\|3451632_3452355_+\|UDP-2,3-diacylglucosamine-hydrolase	unknown	unknown	gnl\|CDD\|235420
CP025627.1\|AUN48696.1\|3462426_3463395_+\|IS5-like-element-IS903B-family-transposase	unknown	unknown	gnl\|CDD\|290455
CP025627.1\|AUN48679.1\|3445906_3446599_-\|fimbrial-chaperone-SfmC	unknown	unknown	gnl\|CDD\|185117
CP025627.1\|AUN48694.1\|3460280_3461516_+\|Zn-dependent-hydrolase	unknown	unknown	gnl\|CDD\|274471
CP025627.1\|AUN48685.1\|3451135_3451630_+\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|182734
CP025627.1\|AUN48687.1\|3452472_3452982_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
CP025627.1\|AUN48684.1\|3449576_3450962_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
CP025627.1\|AUN48692.1\|3457225_3458893_-\|acyl-CoA-synthetase-FdrA	unknown	unknown	gnl\|CDD\|180395
CP025627.1\|AUN48682.1\|3448699_3448912_+\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|183166
CP025627.1\|AUN48693.1\|3459209_3460259_+\|ureidoglycolate-dehydrogenase-(NAD(+))	unknown	unknown	gnl\|CDD\|184985
CP025627.1\|AUN48690.1\|3455130_3455946_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378658
CP025627.1\|AUN48689.1\|3454240_3455134_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|181831
CP025627.1\|AUN48688.1\|3452978_3454046_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
CP025627.1\|AUN48681.1\|3447831_3448698_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|236760
CP025627.1\|AUN48683.1\|3449019_3449541_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
CP025627.1\|AUN48697.1\|3463605_3464751_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|182152
CP025627.1\|AUN48698.1\|3464772_3466074_-\|uracil/xanthine-transporter	unknown	unknown	gnl\|CDD\|183124
CP025627.1\|AUN48695.1\|3461526_3462312_+\|(S)-ureidoglycine-aminohydrolase	unknown	unknown	gnl\|CDD\|200251
CP025627.1\|AUN48680.1\|3446818_3447361_-\|type-1-fimbrial-protein-subunit-FimA	unknown	unknown	gnl\|CDD\|237920

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN48691.1\|3455956_3457216_-\|DUF1116-domain-containing-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.27269e-131
CP025627.1\|AUN48686.1\|3451632_3452355_+\|UDP-2,3-diacylglucosamine-hydrolase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	2.41122e-165
CP025627.1\|AUN48696.1\|3462426_3463395_+\|IS5-like-element-IS903B-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.2686e-57
CP025627.1\|AUN48679.1\|3445906_3446599_-\|fimbrial-chaperone-SfmC	gnl\|CDD\|185117	PRK15195, PRK15195, molecular chaperone FimC.	4.4332e-149
CP025627.1\|AUN48694.1\|3460280_3461516_+\|Zn-dependent-hydrolase	gnl\|CDD\|274471	TIGR03176, AllC, allantoate amidohydrolase. This enzyme catalyzes the breakdown of allantoate, first to ureidoglycine by hydrolysis and then decarboxylation of one of the two equivalent ureido groups. Ureidoglycine then spontaneously exchanges ammonia for water resulting in ureidoglycolate. This enzyme is an alternative to allantoicase (3.5.3.4) which releases urea. [Central intermediary metabolism, Nitrogen metabolism].	0
CP025627.1\|AUN48685.1\|3451135_3451630_+\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|182734	PRK10791, PRK10791, peptidylprolyl isomerase B.	9.12357e-121
CP025627.1\|AUN48687.1\|3452472_3452982_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	1.14024e-91
CP025627.1\|AUN48684.1\|3449576_3450962_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
CP025627.1\|AUN48692.1\|3457225_3458893_-\|acyl-CoA-synthetase-FdrA	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	0
CP025627.1\|AUN48682.1\|3448699_3448912_+\|tyrosine--tRNA-ligase	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	1.38756e-42
CP025627.1\|AUN48693.1\|3459209_3460259_+\|ureidoglycolate-dehydrogenase-(NAD(+))	gnl\|CDD\|184985	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional.	0
CP025627.1\|AUN48690.1\|3455130_3455946_-\|hypothetical-protein	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	3.47659e-37
CP025627.1\|AUN48689.1\|3454240_3455134_-\|carbamate-kinase	gnl\|CDD\|181831	PRK09411, PRK09411, carbamate kinase; Reviewed.	0
CP025627.1\|AUN48688.1\|3452978_3454046_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	2.50904e-178
CP025627.1\|AUN48681.1\|3447831_3448698_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
CP025627.1\|AUN48683.1\|3449019_3449541_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.2285e-30
CP025627.1\|AUN48697.1\|3463605_3464751_-\|glycerate-kinase	gnl\|CDD\|182152	PRK09932, PRK09932, glycerate 3-kinase.	0
CP025627.1\|AUN48698.1\|3464772_3466074_-\|uracil/xanthine-transporter	gnl\|CDD\|183124	PRK11412, PRK11412, uracil/xanthine transporter.	0
CP025627.1\|AUN48695.1\|3461526_3462312_+\|(S)-ureidoglycine-aminohydrolase	gnl\|CDD\|200251	TIGR03214, ura-cupin, putative allantoin catabolism protein. This model represents a protein containing a tandem arrangement of cupin domains (N-terminal part of pfam07883 and C-terminal more distantly related to pfam00190). This protein is found in the vicinity of genes involved in the catabolism of allantoin, a breakdown product of urate and sometimes of urate iteslf. The distribution of pathway components in the genomes in which this family is observed suggests that the function is linked to the allantoate catabolism to glyoxylate pathway (GenProp0686) since it is sometimes found in genomes lacking any elements of the xanthine-to-allantoin pathways (e.g. in Enterococcus faecalis).	2.39799e-151
CP025627.1\|AUN48680.1\|3446818_3447361_-\|type-1-fimbrial-protein-subunit-FimA	gnl\|CDD\|237920	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA.	9.67411e-92

>CP025627.1|AUN48688.1|3452978_3454046_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAERSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEALIPLLPPEYASGVIWAQSKFG
>CP025627.1|AUN48687.1|3452472_3452982_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGAA
>CP025627.1|AUN48686.1|3451632_3452355_+|UDP-2,3-diacylglucosamine-hydrolase
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>CP025627.1|AUN48685.1|3451135_3451630_+|peptidyl-prolyl-cis-trans-isomerase
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTVSE
>CP025627.1|AUN48684.1|3449576_3450962_-|cysteine--tRNA-ligase
MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
>CP025627.1|AUN48683.1|3449019_3449541_+|metal-dependent-hydrolase
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFKFGVAYGNVFGHRGFTHSLVFVFVVPLLCVFIGRRWFRAGLIRCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLPGMLLMGMLWWRRR
>CP025627.1|AUN48682.1|3448699_3448912_+|tyrosine--tRNA-ligase
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>CP025627.1|AUN48681.1|3447831_3448698_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>CP025627.1|AUN48680.1|3446818_3447361_-|type-1-fimbrial-protein-subunit-FimA
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
>CP025627.1|AUN48679.1|3445906_3446599_-|fimbrial-chaperone-SfmC
MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSRSGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN
>CP025627.1|AUN48689.1|3454240_3455134_-|carbamate-kinase
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
>CP025627.1|AUN48690.1|3455130_3455946_-|hypothetical-protein
MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>CP025627.1|AUN48691.1|3455956_3457216_-|DUF1116-domain-containing-protein
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPSWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
>CP025627.1|AUN48692.1|3457225_3458893_-|acyl-CoA-synthetase-FdrA
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALMQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>CP025627.1|AUN48693.1|3459209_3460259_+|ureidoglycolate-dehydrogenase-(NAD(+))
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
>CP025627.1|AUN48694.1|3460280_3461516_+|Zn-dependent-hydrolase
MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKELVATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAWQK
>CP025627.1|AUN48695.1|3461526_3462312_+|(S)-ureidoglycine-aminohydrolase
MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
>CP025627.1|AUN48696.1|3462426_3463395_+|IS5-like-element-IS903B-family-transposase
MKDQITHLPDNADRSVAKQKFKITNWPTYNKALINRGSITFWLDDEAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLRCPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRKLHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHDELRRKKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVKQLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA
>CP025627.1|AUN48697.1|3463605_3464751_-|glycerate-kinase
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQALAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>CP025627.1|AUN48698.1|3464772_3466074_-|uracil/xanthine-transporter
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE

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Crispr_ID: CP025627_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_8

3595315-3595459

Orphan

Consensus_repeat	Method
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025627_8

>merge|CP025627|8|3595315-3595459|CRISPRCasFinder
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCATCGGAGCACTTATTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGGTTCTGGCACCTTTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT

>CP025627|8|8|3595315-3595459|CRISPRCasFinder
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT	CGGAGCACTTATTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGGTTCTGGCACC
TTTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN48821.1\|3600802_3601612_+\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
CP025627.1\|AUN48817.1\|3599136_3599334_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN48820.1\|3600312_3600675_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
CP025627.1\|AUN48807.1\|3584175_3585549_-\|proline-specific-permease-ProY	unknown	unknown	gnl\|CDD\|182566
CP025627.1\|AUN48814.1\|3597584_3597866_-\|DUF2773-domain-containing-protein	unknown	unknown	gnl\|CDD\|287885
CP025627.1\|AUN48813.1\|3595482_3596391_-\|fructokinase	unknown	unknown	gnl\|CDD\|236565
CP025627.1\|AUN48806.1\|3582202_3584017_-\|alpha-glycosidase	unknown	unknown	gnl\|CDD\|236759
CP025627.1\|AUN48804.1\|3580453_3581524_-\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	unknown	unknown	gnl\|CDD\|234666
CP025627.1\|AUN48812.1\|3590781_3593928_+\|nuclease-SbcCD-subunit-C	unknown	unknown	gnl\|CDD\|182330
CP025627.1\|AUN48815.1\|3598073_3598358_-\|pyrimidine/purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|182565
CP025627.1\|AUN48818.1\|3599364_3599556_-\|protein-YaiA	unknown	unknown	gnl\|CDD\|182421
CP025627.1\|AUN50045.1\|3596515_3597427_+\|recombination-associated-protein-RdgC	unknown	unknown	gnl\|CDD\|225521
CP025627.1\|AUN48805.1\|3581616_3582198_+\|ACP-phosphodiesterase	unknown	unknown	gnl\|CDD\|182207
CP025627.1\|AUN48816.1\|3598429_3599107_-\|protein-AroM	unknown	unknown	gnl\|CDD\|182491
CP025627.1\|AUN48809.1\|3587350_3588646_-\|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|182895
CP025627.1\|AUN50044.1\|3594053_3595238_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|182234
CP025627.1\|AUN48819.1\|3599605_3600130_-\|shikimate-kinase	unknown	unknown	gnl\|CDD\|235153
CP025627.1\|AUN48811.1\|3589582_3590785_+\|exonuclease-sbcCD-subunit-D	unknown	unknown	gnl\|CDD\|182871
CP025627.1\|AUN48810.1\|3588703_3589393_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|182277
CP025627.1\|AUN48808.1\|3585624_3586944_-\|branched-chain-amino-acid-transport-system-2-carrier-protein	unknown	unknown	gnl\|CDD\|185331

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN48821.1\|3600802_3601612_+\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.87564e-128
CP025627.1\|AUN48820.1\|3600312_3600675_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	3.04641e-60
CP025627.1\|AUN48807.1\|3584175_3585549_-\|proline-specific-permease-ProY	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
CP025627.1\|AUN48814.1\|3597584_3597866_-\|DUF2773-domain-containing-protein	gnl\|CDD\|287885	pfam10971, DUF2773, Protein of unknown function (DUF2773). This family of proteins with unknown function appears to be restricted to Enterobacteriaceae.	1.10173e-36
CP025627.1\|AUN48813.1\|3595482_3596391_-\|fructokinase	gnl\|CDD\|236565	PRK09557, PRK09557, fructokinase; Reviewed.	0
CP025627.1\|AUN48806.1\|3582202_3584017_-\|alpha-glycosidase	gnl\|CDD\|236759	PRK10785, PRK10785, maltodextrin glucosidase; Provisional.	0
CP025627.1\|AUN48804.1\|3580453_3581524_-\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	gnl\|CDD\|234666	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional.	0
CP025627.1\|AUN48812.1\|3590781_3593928_+\|nuclease-SbcCD-subunit-C	gnl\|CDD\|182330	PRK10246, PRK10246, exonuclease subunit SbcC; Provisional.	0
CP025627.1\|AUN48815.1\|3598073_3598358_-\|pyrimidine/purine-nucleoside-phosphorylase	gnl\|CDD\|182565	PRK10579, PRK10579, pyrimidine/purine nucleoside phosphorylase.	5.85948e-64
CP025627.1\|AUN48818.1\|3599364_3599556_-\|protein-YaiA	gnl\|CDD\|182421	PRK10380, PRK10380, hypothetical protein; Provisional.	5.14477e-31
CP025627.1\|AUN50045.1\|3596515_3597427_+\|recombination-associated-protein-RdgC	gnl\|CDD\|225521	COG2974, RdgC, DNA recombination-dependent growth factor C [DNA replication, recombination, and repair].	0
CP025627.1\|AUN48805.1\|3581616_3582198_+\|ACP-phosphodiesterase	gnl\|CDD\|182207	PRK10045, PRK10045, ACP phosphodiesterase.	3.03368e-136
CP025627.1\|AUN48816.1\|3598429_3599107_-\|protein-AroM	gnl\|CDD\|182491	PRK10481, PRK10481, hypothetical protein; Provisional.	2.13662e-120
CP025627.1\|AUN48809.1\|3587350_3588646_-\|PAS-domain-containing-sensor-histidine-kinase	gnl\|CDD\|182895	PRK11006, phoR, phosphate regulon sensor histidine kinase PhoR.	0
CP025627.1\|AUN50044.1\|3594053_3595238_+\|MFS-transporter	gnl\|CDD\|182234	PRK10091, PRK10091, MFS transport protein AraJ; Provisional.	0
CP025627.1\|AUN48819.1\|3599605_3600130_-\|shikimate-kinase	gnl\|CDD\|235153	PRK03731, aroL, shikimate kinase AroL.	2.43812e-108
CP025627.1\|AUN48811.1\|3589582_3590785_+\|exonuclease-sbcCD-subunit-D	gnl\|CDD\|182871	PRK10966, PRK10966, exonuclease subunit SbcD; Provisional.	0
CP025627.1\|AUN48810.1\|3588703_3589393_-\|DNA-binding-response-regulator	gnl\|CDD\|182277	PRK10161, PRK10161, phosphate response regulator transcription factor PhoB.	5.1688e-159
CP025627.1\|AUN48808.1\|3585624_3586944_-\|branched-chain-amino-acid-transport-system-2-carrier-protein	gnl\|CDD\|185331	PRK15433, PRK15433, branched-chain amino acid transporter carrier protein BrnQ.	0

>CP025627.1|AUN50044.1|3594053_3595238_+|MFS-transporter
MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGNLREQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADTPVLAKPLG
>CP025627.1|AUN48812.1|3590781_3593928_+|nuclease-SbcCD-subunit-C
MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAVK
>CP025627.1|AUN48811.1|3589582_3590785_+|exonuclease-sbcCD-subunit-D
MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYIALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLHTLAGEHEA
>CP025627.1|AUN48810.1|3588703_3589393_-|DNA-binding-response-regulator
MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF
>CP025627.1|AUN48809.1|3587350_3588646_-|PAS-domain-containing-sensor-histidine-kinase
MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRDFSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNEKVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD
>CP025627.1|AUN48808.1|3585624_3586944_-|branched-chain-amino-acid-transport-system-2-carrier-protein
MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTAAFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRTATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALVILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGVTEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFGGGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLSQLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAFSDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH
>CP025627.1|AUN48807.1|3584175_3585549_-|proline-specific-permease-ProY
MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHDRQLAENQ
>CP025627.1|AUN48806.1|3582202_3584017_-|alpha-glycosidase
MLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEVVLPASPFLNAVQWQCKEGHGQLTDGILALPAISATVWMN
>CP025627.1|AUN48805.1|3581616_3582198_+|ACP-phosphodiesterase
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASRKAL
>CP025627.1|AUN48804.1|3580453_3581524_-|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA
MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
>CP025627.1|AUN48813.1|3595482_3596391_-|fructokinase
MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIATLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRLANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPLPWMDEDELRYREEVPCYCGKQGCIETFISGTGFAMDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGECETPVRKAKHGDSSGVRGAAWLWPQE
>CP025627.1|AUN50045.1|3596515_3597427_+|recombination-associated-protein-RdgC
MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
>CP025627.1|AUN48814.1|3597584_3597866_-|DUF2773-domain-containing-protein
MLQSRNDHLRQTALRNAHTPALLLTTLTEPQDRSLAINNPQLAADVKTAWLKEDPSLLLFVEQPDLSLLRDLVKTGATRKIRSEARHRLEEKQ
>CP025627.1|AUN48815.1|3598073_3598358_-|pyrimidine/purine-nucleoside-phosphorylase
MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
>CP025627.1|AUN48816.1|3598429_3599107_-|protein-AroM
MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREEVMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANISSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSLGNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIARLAAELLV
>CP025627.1|AUN48817.1|3599136_3599334_-|hypothetical-protein
MPLQGICVTFFIIHVFLIIRILNNNNPLLESFGIFTLCRARLLLRFLSFVAQVSVSSGASHLPGN
>CP025627.1|AUN48818.1|3599364_3599556_-|protein-YaiA
MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEHPTAQEAMDAKKRYEDPDKE
>CP025627.1|AUN48819.1|3599605_3600130_-|shikimate-kinase
MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
>CP025627.1|AUN48820.1|3600312_3600675_-|YaiI/YqxD-family-protein
MGGCRRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
>CP025627.1|AUN48821.1|3600802_3601612_+|pyrroline-5-carboxylate-reductase
MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS

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Crispr_ID: CP025627_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025627_9

4160190-4160339

Orphan

Consensus_repeat	Method
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025627_9

>merge|CP025627|9|4160190-4160339|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCATGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

>CP025627|9|9|4160190-4160339|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCA
TGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
CP025627.1\|AUN49339.1\|4171395_4171791_+\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100005
CP025627.1\|AUN50066.1\|4149753_4150338_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN49336.1\|4169290_4169743_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345
CP025627.1\|AUN49328.1\|4157274_4158375_-\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
CP025627.1\|AUN49331.1\|4160949_4163805_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP025627.1\|AUN49326.1\|4154529_4156032_+\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
CP025627.1\|AUN49335.1\|4166363_4167368_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
CP025627.1\|AUN49337.1\|4169887_4170481_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP025627.1\|AUN49333.1\|4165236_4165740_+\|amino-acid-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP025627.1\|AUN49322.1\|4150399_4150630_-\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|225848
CP025627.1\|AUN49327.1\|4156192_4157275_-\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
CP025627.1\|AUN49338.1\|4170551_4171265_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
CP025627.1\|AUN49329.1\|4158641_4160153_+\|cytosol-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
CP025627.1\|AUN49324.1\|4151675_4152938_-\|DUF4102-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
CP025627.1\|AUN49330.1\|4160506_4160950_+\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
CP025627.1\|AUN49321.1\|4149401_4149761_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN49334.1\|4165785_4166202_-\|regulator-of-ribonuclease-activity-B	unknown	unknown	gnl\|CDD\|236876
CP025627.1\|AUN49325.1\|4153382_4154402_+\|aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
CP025627.1\|AUN49323.1\|4151007_4151646_-\|hypothetical-protein	unknown	unknown	unknown
CP025627.1\|AUN49332.1\|4163856_4165044_-\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719

Protein	Function_ID	Function_description	E-value
CP025627.1\|AUN49339.1\|4171395_4171791_+\|RidA-family-protein	gnl\|CDD\|100005	cd02198, YjgH_like, YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	6.86533e-58
CP025627.1\|AUN49325.1\|4153382_4154402_+\|aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	8.44277e-169
CP025627.1\|AUN49328.1\|4157274_4158375_-\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
CP025627.1\|AUN49338.1\|4170551_4171265_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	1.04315e-149
CP025627.1\|AUN49326.1\|4154529_4156032_+\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
CP025627.1\|AUN49335.1\|4166363_4167368_+\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
CP025627.1\|AUN49337.1\|4169887_4170481_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.97779e-10
CP025627.1\|AUN49322.1\|4150399_4150630_-\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	2.99457e-15
CP025627.1\|AUN49336.1\|4169290_4169743_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	4.50803e-70
CP025627.1\|AUN49331.1\|4160949_4163805_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
CP025627.1\|AUN49329.1\|4158641_4160153_+\|cytosol-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
CP025627.1\|AUN49324.1\|4151675_4152938_-\|DUF4102-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	6.37182e-82
CP025627.1\|AUN49330.1\|4160506_4160950_+\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
CP025627.1\|AUN49327.1\|4156192_4157275_-\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
CP025627.1\|AUN49332.1\|4163856_4165044_-\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	3.73478e-110
CP025627.1\|AUN49334.1\|4165785_4166202_-\|regulator-of-ribonuclease-activity-B	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	8.03891e-69
CP025627.1\|AUN49333.1\|4165236_4165740_+\|amino-acid-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.71083e-18

>CP025627.1|AUN49329.1|4158641_4160153_+|cytosol-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>CP025627.1|AUN49328.1|4157274_4158375_-|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>CP025627.1|AUN49327.1|4156192_4157275_-|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>CP025627.1|AUN49326.1|4154529_4156032_+|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLTLEQQGATHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASTEQQNNPAVKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>CP025627.1|AUN49325.1|4153382_4154402_+|aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
>CP025627.1|AUN49324.1|4151675_4152938_-|DUF4102-domain-containing-protein
MKLNARQIETAKPKEKAYKMADGGGLYLEVSPKGSKYWRMKYRRPSDKKEDRLAFGVYPTVTLAEARGKRDAAKKLLSQGIDPKAEQKGAQAEIEGAYLFETIARQWHASNLTWSEDHSRRVLLTLEQYIFPSIGQIDARTLRTSQLLNPIKAVDTAGKHDVAQRLMQRVTAIMRFGVQNDLLESNPACDMAGALLSVKATHHPALPPKRIPELLERLSRYKGRLMTRLAVELTLLTFIRSSEMRFARWSEVNFERSEWTIPGIRKPIPGVKHSERGMKMKTEHIVPLSKQAFDIFKRLHALSGKGEVIFPSDHDPKKVMSENTVNNALRVMGYDTKTEVCGHGFRTMARGALSESKLWNDDAIERQLSHVERKNVKGSYMHTSEYLEERRLMLQWWADYIDANKNGSVTPYDFARMHGK
>CP025627.1|AUN49323.1|4151007_4151646_-|hypothetical-protein
MNNTQFDNNLFYFNRLTYITPHEVALAMNGFDYDTENDELTEVQLKEVIRLRKAITRNLQLINEYKNVSATQKVEANLLLTAAYIFQREGIVPVEIKERIENALRQQVKNKDWSDILMTLGGSELYEVGKKLRSNGRGQYRKDDEDNYSCKLIYLLIELLKRHGKVSYSDNSVIYNDIVSFCNENEILMKGVKKATFYKKIKLGKDIIKYGE
>CP025627.1|AUN49322.1|4150399_4150630_-|AlpA-family-phage-regulatory-protein
MEYANSFSDNQTLISAKEVLRRVQRSKAWLYKQLANNTFPRPVKIGTRAISFVESEVDHWIQEQIYASRGERYENH
>CP025627.1|AUN50066.1|4149753_4150338_-|hypothetical-protein
METERTSVGFSIQLPCSGLFFLRCRRLISPFTAVTMNCAFVSPSSRLLSNSATTSCGKRALSCCDLLLVELVAITGSPRVRCDSVYAKKMIIKSLKCDSLKGSFKIKGAIHLVSAKPDSAATLTGLLTNPLNEVTKMAKQKCTWLFAAINRSQRNARPVMLRITADNERSARRRLAPDYVLSFAGRIPCGGEHA
>CP025627.1|AUN49321.1|4149401_4149761_-|hypothetical-protein
MRNYPHPGERWQHERGWTVTIIRLIEASPSVALVNPEFSCEVLIRHDSDNQLSSCPLAWFEQRYTRLFDVPLLKPAPAPAGGSGSGPLTLHPSVLFIRWRERSIRRSAEPDDGHYSKFL
>CP025627.1|AUN49330.1|4160506_4160950_+|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>CP025627.1|AUN49331.1|4160949_4163805_+|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIDGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>CP025627.1|AUN49332.1|4163856_4165044_-|DUF898-domain-containing-protein
MNGVNVGKDNPRHAFVFTGKGGEYFLICLVNFLLTIITLGIYGPWALVKCRRYICQHVTLKGQPFSYKGTGGAIFVSMLLIMVVYFLSISCVAGQHFVLAFLLFALLICGIPCMAVKSLQYQANMTSLNGIRFGFNCSMLRAWWVMLGLPVLLALAFWLVLYLIAQVTTSIGGLFFNLVVLSLLSVIGLGVINGITYSKWMPLLGNNATFGVHQFSIKVNVKECIKGCMLAILTMVPFIIVIGIMIAPVFQQLIMMSMLGQSEAGGELILQYYPQIMASYFLYFVAILVFASYLYVTLRSLFLNNLTLANGTIRFHSSVTTFGMLLRMLAVLMGSSITCGLAYPWLKMWMVSWIANNTHVQGDLDSLELTNDDKPQDSGPLMWISRGIMPYVPFI
>CP025627.1|AUN49333.1|4165236_4165740_+|amino-acid-N-acetyltransferase
MNVVASPALRLRKLTVADNPAIASVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>CP025627.1|AUN49334.1|4165785_4166202_-|regulator-of-ribonuclease-activity-B
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEEDDGVRH
>CP025627.1|AUN49335.1|4166363_4167368_+|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNNKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSN
>CP025627.1|AUN49336.1|4169290_4169743_-|YhcH/YjgK/YiaL-family-protein
MIIGNIHNLQPWLPQELRQAIEHVKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>CP025627.1|AUN49337.1|4169887_4170481_-|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILLDDRPVGECLVEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE
>CP025627.1|AUN49338.1|4170551_4171265_+|SDR-family-NAD(P)-dependent-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRHFVTDGANVRFTYAGSKDAAERLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHGFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>CP025627.1|AUN49339.1|4171395_4171791_+|RidA-family-protein
MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGTPEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAPPYPNWTAVGVTWLAGFDFEIKVIARIPAQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025627_5	5.1\|2948163\|40\|CP025627\|CRISPRCasFinder	2948163-2948202	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
CP025627_4	4.1\|2279225\|38\|CP025627\|CRISPRCasFinder	2279225-2279262	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
CP025627_2	2.5\|1113392\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113392-1113423	32	NC_021229	Arthrobacter nicotinovorans pAO1 megaplasmid sequence, strain ATCC 49919	65474-65505	5	0.844
CP025627_1	1.7\|1087325\|31\|CP025627\|CRISPRCasFinder	1087325-1087355	31	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	755174-755204	6	0.806
CP025627_1	1.7\|1087325\|31\|CP025627\|CRISPRCasFinder	1087325-1087355	31	MH067970	Arthrobacter sp. strain ANT_H40 plasmid pA40H1, complete sequence	47826-47856	6	0.806
CP025627_2	2.5\|1113392\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113392-1113423	32	NZ_CP017422	Arthrobacter sp. ZXY-2 plasmid pZXY21, complete sequence	208287-208318	6	0.812
CP025627_1	1.10\|1087508\|31\|CP025627\|CRISPRCasFinder	1087508-1087538	31	MG945629	UNVERIFIED: Microviridae sp. isolate 6200-1602, complete genome	4209-4239	7	0.774
CP025627_1	1.10\|1087508\|31\|CP025627\|CRISPRCasFinder	1087508-1087538	31	MK814759	Gordonia phage Reyja, complete genome	4468-4498	7	0.774
CP025627_2	2.6\|1113453\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113453-1113484	32	MK416018	Klebsiella phage ST147-VIM1phi7.1, complete genome	24790-24821	7	0.781
CP025627_2	2.7\|1113514\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113514-1113545	32	MF351863	Synechococcus phage Bellamy, complete genome	123998-124029	7	0.781
CP025627_1	1.2\|1087323\|33\|CP025627\|PILER-CR,CRT	1087323-1087355	33	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	755172-755204	8	0.758
CP025627_1	1.7\|1087325\|31\|CP025627\|CRISPRCasFinder	1087325-1087355	31	NZ_CP007070	Rhizobium leguminosarum bv. trifolii CB782 plasmid unnamed, complete sequence	191920-191950	8	0.742
CP025627_1	1.9\|1087447\|31\|CP025627\|CRISPRCasFinder	1087447-1087477	31	NZ_CP033579	Vibrio mediterranei strain 117-T6 plasmid unnamed, complete sequence	47369-47399	8	0.742
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	375744-375776	8	0.758
CP025627_2	2.5\|1113392\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113392-1113423	32	MK113951	Phage 5P_3, complete genome	11967-11998	8	0.75
CP025627_2	2.5\|1113392\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113392-1113423	32	AP017924	Ralstonia phage RP12 DNA, complete genome	11643-11674	8	0.75
CP025627_2	2.11\|1113758\|32\|CP025627\|CRISPRCasFinder,CRT	1113758-1113789	32	NZ_AP018516	Acetobacter orientalis strain FAN1 plasmid pAOF1, complete sequence	48296-48327	8	0.75
CP025627_1	1.6\|1087264\|31\|CP025627\|CRISPRCasFinder	1087264-1087294	31	MF158039	Shigella phage Sf12, complete genome	4976-5006	9	0.71
CP025627_1	1.6\|1087264\|31\|CP025627\|CRISPRCasFinder	1087264-1087294	31	MF158042	Shigella phage Sd1, complete genome	939-969	9	0.71
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_CP010957	Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence	26182-26214	9	0.727
CP025627_2	2.6\|1113453\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113453-1113484	32	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	1143591-1143622	9	0.719
CP025627_2	2.6\|1113453\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113453-1113484	32	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	891493-891524	9	0.719
CP025627_2	2.6\|1113453\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113453-1113484	32	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	1143594-1143625	9	0.719
CP025627_2	2.6\|1113453\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113453-1113484	32	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	315030-315061	9	0.719
CP025627_2	2.6\|1113453\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113453-1113484	32	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	1123532-1123563	9	0.719
CP025627_1	1.6\|1087264\|31\|CP025627\|CRISPRCasFinder	1087264-1087294	31	MT840185	Bacteriophage sp. Joined_contig_19 genomic sequence	64310-64340	10	0.677
CP025627_1	1.6\|1087264\|31\|CP025627\|CRISPRCasFinder	1087264-1087294	31	KF356199	Microcystis phage MaMV-DC, complete genome	50157-50187	10	0.677
CP025627_1	1.6\|1087264\|31\|CP025627\|CRISPRCasFinder	1087264-1087294	31	NC_008562	Microcystis phage Ma-LMM01 DNA, complete genome	44744-44774	10	0.677
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	CP046443	Pseudomonas coronafaciens pv. coronafaciens strain B19001 plasmid unnamed2, complete sequence	31933-31965	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_LT963392	Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence	103013-103045	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_LT963392	Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence	110510-110542	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_CP034079	Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-1, complete sequence	48454-48486	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_CP034080	Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-2, complete sequence	39480-39512	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NC_005918	Pseudomonas syringae pv. maculicola strain ES4326 plasmid pPMA4326A, complete sequence	31117-31149	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_CP047262	Pseudomonas syringae pv. maculicola str. ES4326 plasmid pPma4326A, complete sequence	30966-30998	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_CP026560	Pseudomonas amygdali pv. morsprunorum strain R15244 plasmid p3_tig5, complete sequence	19118-19150	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_LT963406	Pseudomonas syringae pv. avii isolate CFBP3846 plasmid PP4, complete sequence	54820-54852	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	LT985193	Pseudomonas syringae strain CFBP 2116 genome assembly, plasmid: PP2	32077-32109	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_LT963393	Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP2, complete sequence	50597-50629	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_LT985210	Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP1, complete sequence	105842-105874	10	0.697
CP025627_2	2.2\|1113208\|33\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113208-1113240	33	NZ_LT985211	Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP2, complete sequence	84272-84304	10	0.697
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NZ_CP028970	Aminobacter sp. MSH1 plasmid pUSP2, complete sequence	156123-156154	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NZ_CP053984	Achromobacter pestifer strain FDAARGOS_790 plasmid unnamed, complete sequence	21888-21919	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_010935	Comamonas testosteroni CNB-1 plasmid pCNB, complete sequence	28766-28797	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	JX469826	Uncultured bacterium plasmid pB12, complete sequence	11283-11314	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	JN106171	Uncultured bacterium plasmid pAKD26, complete sequence	11289-11320	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_016968	Comamonas testosteroni plasmid pTB30, complete sequence	11287-11318	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_016978	Comamonas testosteroni plasmid pI2, complete sequence	11272-11303	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NZ_CP017760	Cupriavidus necator strain NH9 plasmid pENH91, complete sequence	67078-67109	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NZ_CP053554	Diaphorobacter sp. JS3050 plasmid pDCNB, complete sequence	4235-4266	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_019263	Delftia acidovorans plasmid pLME1, complete sequence	11288-11319	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_019264	Delftia acidovorans plasmid pNB8c, complete sequence	11288-11319	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_019283	Delftia acidovorans plasmid pC1-1, complete sequence	11288-11319	10	0.688
CP025627_2	2.4\|1113331\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113331-1113362	32	NC_006830	Achromobacter xylosoxidans A8 plasmid pA81, complete sequence	11350-11381	10	0.688
CP025627_2	2.5\|1113392\|32\|CP025627\|PILER-CR,CRISPRCasFinder,CRT	1113392-1113423	32	NC_002580	Propionibacterium freudenreichii plasmid p545, complete sequence	2898-2929	10	0.688
CP025627_8	8.1\|3595358\|59\|CP025627\|CRISPRCasFinder	3595358-3595416	59	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	97-155	10	0.831
CP025627_1	1.1\|1087262\|33\|CP025627\|PILER-CR,CRT	1087262-1087294	33	MF158039	Shigella phage Sf12, complete genome	4974-5006	11	0.667
CP025627_1	1.1\|1087262\|33\|CP025627\|PILER-CR,CRT	1087262-1087294	33	MF158042	Shigella phage Sd1, complete genome	937-969	11	0.667
CP025627_8	8.1\|3595358\|59\|CP025627\|CRISPRCasFinder	3595358-3595416	59	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	40375-40433	11	0.814

1. spacer 5.1|2948163|40|CP025627|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 4.1|2279225|38|CP025627|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

3. spacer 2.5|1113392|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_021229 (Arthrobacter nicotinovorans pAO1 megaplasmid sequence, strain ATCC 49919) position: , mismatch: 5, identity: 0.844

-ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
tccgctcg-gcaggctgcaacgcaagccgccca	Protospacer
 *.*** * ** ******** ************

4. spacer 1.7|1087325|31|CP025627|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.806

cgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
cgtggtcgtgggtgctgctgttgctggagcg	Protospacer
*******.**************** *.. *.

5. spacer 1.7|1087325|31|CP025627|CRISPRCasFinder matches to MH067970 (Arthrobacter sp. strain ANT_H40 plasmid pA40H1, complete sequence) position: , mismatch: 6, identity: 0.806

cgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
cgtggtcaagggtgctgctgttcccacgcct	Protospacer
******** ************* * . ***

6. spacer 2.5|1113392|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017422 (Arthrobacter sp. ZXY-2 plasmid pZXY21, complete sequence) position: , mismatch: 6, identity: 0.812

-ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
tccgctcg-gcaggctgcaacgcaagccgcccc	Protospacer
 *.*** * ** ******** ***********

7. spacer 1.10|1087508|31|CP025627|CRISPRCasFinder matches to MG945629 (UNVERIFIED: Microviridae sp. isolate 6200-1602, complete genome) position: , mismatch: 7, identity: 0.774

agcctgacgagactactgaggccgttctgtc	CRISPR spacer
aaaaggccaagactactgaggccgttcagtc	Protospacer
*.   * *.****************** ***

8. spacer 1.10|1087508|31|CP025627|CRISPRCasFinder matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 7, identity: 0.774

agcctgacgagactactgaggccgttctgtc-	CRISPR spacer
agcctgacgaggctactggggcca-gcggtgg	Protospacer
***********.******.****.  * **

9. spacer 2.6|1113453|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to MK416018 (Klebsiella phage ST147-VIM1phi7.1, complete genome) position: , mismatch: 7, identity: 0.781

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
cccatcagcgcgttttttggcggtgtgatgga	Protospacer
****.************** *** *. **.*

10. spacer 2.7|1113514|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to MF351863 (Synechococcus phage Bellamy, complete genome) position: , mismatch: 7, identity: 0.781

ttgaactcaccacgattgttaatatggacgat	CRISPR spacer
aaggtatcaccacgattgttgatatgggcgat	Protospacer
  *.  **************.******.****

11. spacer 1.2|1087323|33|CP025627|PILER-CR,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.758

gacgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
tccgtggtcgtgggtgctgctgttgctggagcg	Protospacer
  *******.**************** *.. *.

12. spacer 1.7|1087325|31|CP025627|CRISPRCasFinder matches to NZ_CP007070 (Rhizobium leguminosarum bv. trifolii CB782 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

cgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
tgcggtcatggatgctgatgttgcagtgatg	Protospacer
.*.********.***** ******** * ..

13. spacer 1.9|1087447|31|CP025627|CRISPRCasFinder matches to NZ_CP033579 (Vibrio mediterranei strain 117-T6 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

atagcaatagtccatagatttgcgaaaacag	CRISPR spacer
aggtttgtagtccattgatttgcgaaaactg	Protospacer
* . . .******** ************* *

14. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 8, identity: 0.758

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ctgatcgcgcattacctgcgcgtcgccgacgcg	Protospacer
* .*********  ************** *

15. spacer 2.5|1113392|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to MK113951 (Phage 5P_3, complete genome) position: , mismatch: 8, identity: 0.75

ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
gagcatcggctggctgcaaggcaagctgcccc	Protospacer
  **   .******************.****

16. spacer 2.5|1113392|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to AP017924 (Ralstonia phage RP12 DNA, complete genome) position: , mismatch: 8, identity: 0.75

ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
gcggaagcgctggctgcacggcaagcggccca	Protospacer
 .*  .* ********** ******* *****

17. spacer 2.11|1113758|32|CP025627|CRISPRCasFinder,CRT matches to NZ_AP018516 (Acetobacter orientalis strain FAN1 plasmid pAOF1, complete sequence) position: , mismatch: 8, identity: 0.75

gcaacgacggtgagatttcacgcctgacgctg	CRISPR spacer
tcaacgacggtaagatgtcacgcctaaagaat	Protospacer
 **********.**** ********.* *

18. spacer 1.6|1087264|31|CP025627|CRISPRCasFinder matches to MF158039 (Shigella phage Sf12, complete genome) position: , mismatch: 9, identity: 0.71

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
tgtttgcagcattaacgctccccaagtgccg	Protospacer
*******.************ ***.   ..

19. spacer 1.6|1087264|31|CP025627|CRISPRCasFinder matches to MF158042 (Shigella phage Sd1, complete genome) position: , mismatch: 9, identity: 0.71

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
tgtttgcagcattaacgctctccaagtgccg	Protospacer
*******.************ ***.   ..

20. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010957 (Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence) position: , mismatch: 9, identity: 0.727

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ctcgacccgcataccttgcgtgtcgccgcctcg	Protospacer
*  . * ********.****.**********

21. spacer 2.6|1113453|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

22. spacer 2.6|1113453|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

23. spacer 2.6|1113453|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

24. spacer 2.6|1113453|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

25. spacer 2.6|1113453|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

26. spacer 1.6|1087264|31|CP025627|CRISPRCasFinder matches to MT840185 (Bacteriophage sp. Joined_contig_19 genomic sequence) position: , mismatch: 10, identity: 0.677

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
gtgcggcggcattaatgctcacaagtatggt	Protospacer
   . **********.****** *****  .

27. spacer 1.6|1087264|31|CP025627|CRISPRCasFinder matches to KF356199 (Microcystis phage MaMV-DC, complete genome) position: , mismatch: 10, identity: 0.677

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
gtgcggcggcattaatgctcacaagtatggt	Protospacer
   . **********.****** *****  .

28. spacer 1.6|1087264|31|CP025627|CRISPRCasFinder matches to NC_008562 (Microcystis phage Ma-LMM01 DNA, complete genome) position: , mismatch: 10, identity: 0.677

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
gtgcggcggcattaatgctcacaagtatggt	Protospacer
   . **********.****** *****  .

29. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to CP046443 (Pseudomonas coronafaciens pv. coronafaciens strain B19001 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

30. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963392 (Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

31. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963392 (Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

32. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034079 (Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

33. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034080 (Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

34. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_005918 (Pseudomonas syringae pv. maculicola strain ES4326 plasmid pPMA4326A, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

35. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047262 (Pseudomonas syringae pv. maculicola str. ES4326 plasmid pPma4326A, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

36. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026560 (Pseudomonas amygdali pv. morsprunorum strain R15244 plasmid p3_tig5, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

37. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963406 (Pseudomonas syringae pv. avii isolate CFBP3846 plasmid PP4, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

38. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to LT985193 (Pseudomonas syringae strain CFBP 2116 genome assembly, plasmid: PP2) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

39. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963393 (Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

40. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT985210 (Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

41. spacer 2.2|1113208|33|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT985211 (Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

42. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028970 (Aminobacter sp. MSH1 plasmid pUSP2, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
acgtcaccccggaagcgattgccagcacacgc	Protospacer
.  ********.*** **********  .* .

43. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053984 (Achromobacter pestifer strain FDAARGOS_790 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

44. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_010935 (Comamonas testosteroni CNB-1 plasmid pCNB, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

45. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to JX469826 (Uncultured bacterium plasmid pB12, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

46. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to JN106171 (Uncultured bacterium plasmid pAKD26, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

47. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_016968 (Comamonas testosteroni plasmid pTB30, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

48. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_016978 (Comamonas testosteroni plasmid pI2, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

49. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017760 (Cupriavidus necator strain NH9 plasmid pENH91, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

50. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053554 (Diaphorobacter sp. JS3050 plasmid pDCNB, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

51. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_019263 (Delftia acidovorans plasmid pLME1, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

52. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_019264 (Delftia acidovorans plasmid pNB8c, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

53. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_019283 (Delftia acidovorans plasmid pC1-1, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

54. spacer 2.4|1113331|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_006830 (Achromobacter xylosoxidans A8 plasmid pA81, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

55. spacer 2.5|1113392|32|CP025627|PILER-CR,CRISPRCasFinder,CRT matches to NC_002580 (Propionibacterium freudenreichii plasmid p545, complete sequence) position: , mismatch: 10, identity: 0.688

ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
ccctgagagctggctgccacgcaagccgctgg	Protospacer
*. . .*********** * *********. .

56. spacer 8.1|3595358|59|CP025627|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 10, identity: 0.831

-cggagcacttattgccggatgcggcgtgaacgccttatccggcctacggttctggcacc	CRISPR spacer
tcagtgcac-gatcgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctc	Protospacer
 *.* ****  **.**************************** ************   .*

57. spacer 1.1|1087262|33|CP025627|PILER-CR,CRT matches to MF158039 (Shigella phage Sf12, complete genome) position: , mismatch: 11, identity: 0.667

tgtgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
attgtttgcagcattaacgctccccaagtgccg	Protospacer
  *******.************ ***.   ..

58. spacer 1.1|1087262|33|CP025627|PILER-CR,CRT matches to MF158042 (Shigella phage Sd1, complete genome) position: , mismatch: 11, identity: 0.667

tgtgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
attgtttgcagcattaacgctctccaagtgccg	Protospacer
  *******.************ ***.   ..

59. spacer 8.1|3595358|59|CP025627|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 11, identity: 0.814

cggagcacttattgccggatgcggcgtgaacgccttatccggcctacggttctggcacc-	CRISPR spacer
ggtacggctttttgccggatgcggcgtaaacgccttatccggcctacggtt-tggtgcga	Protospacer
 * *  .*** ****************.*********************** ***..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1121244 : 1134427

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN46582.1\|1121244_1122006_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.4e-59	48.0
AUN46583.1\|1121999_1122626_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.7e-36	49.7
AUN46584.1\|1122765_1123905_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	1.7e-06	35.6
AUN46585.1\|1123967_1124960_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.1e-32	37.6
AUN46586.1\|1125053_1126418_-	permease	NA	NA	NA	NA
AUN46587.1\|1126506_1127283_-	hypothetical protein	NA	NA	NA	NA
AUN46588.1\|1127287_1127926_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
AUN46589.1\|1127922_1129185_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.7e-135	61.4
AUN46590.1\|1129181_1130090_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	5.1e-118	76.5
AUN46591.1\|1130285_1131053_+	DeoR family transcriptional regulator	A0A077SK06	Escherichia_phage	7.4e-70	56.3
AUN46592.1\|1131103_1131760_-	serine/threonine protein phosphatase	A0A222YWF0	Escherichia_phage	6.2e-49	46.3
AUN46593.1\|1131865_1134427_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	3.0e-30	20.6

DBSCAN-SWA_2

1738375 : 1747818

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN47130.1\|1738375_1739302_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-23	30.8
AUN47131.1\|1739306_1740038_+	proline/glycine betaine ABC transporter permease ProW	NA	NA	NA	NA
AUN47132.1\|1740018_1740126_-	hypothetical protein	NA	NA	NA	NA
AUN47133.1\|1740185_1740917_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
AUN47134.1\|1741138_1742824_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
AUN47135.1\|1742820_1743540_+	two-component system response regulator YehT	NA	NA	NA	NA
AUN47136.1\|1743586_1744057_+	DUF1456 domain-containing protein	Q9EYF4	Enterobacteria_phage	5.2e-82	99.4
AUN47137.1\|1744098_1744560_-	hypothetical protein	Q9EYF5	Enterobacteria_phage	5.4e-76	99.3
AUN47138.1\|1744684_1746685_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
AUN47139.1\|1746681_1747818_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	5.0e-163	97.4

DBSCAN-SWA_3

1836685 : 1846996

Enterobacteria_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN47204.1\|1836685_1837360_+	hypothetical protein	A0A1V0E6Q2	Klebsiella_phage	6.4e-09	25.2
AUN47205.1\|1837395_1838724_+	flippase	NA	NA	NA	NA
AUN47206.1\|1838871_1839195_+	serine acetyltransferase	A0A191KBJ5	Streptococcus_virus	1.9e-11	39.0
AUN47207.1\|1839366_1840773_+	phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	M4QQM4	Ostreococcus_lucimarinus_virus	4.7e-38	28.7
AUN47208.1\|1840997_1842062_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.4e-105	55.0
AUN47209.1\|1842088_1842958_+	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	9.8e-111	66.7
AUN47210.1\|1842989_1843880_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.7e-28	33.2
AUN47211.1\|1843894_1844449_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	1.0e-52	58.8
AUN47212.1\|1844629_1845796_+	UDP-glucose 6-dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	9.1e-112	54.7
AUN47213.1\|1845988_1846996_+	NAD-dependent epimerase	E3T4Y8	Cafeteria_roenbergensis_virus	1.2e-30	28.6

DBSCAN-SWA_4

2771582 : 2832156

Escherichia_phage(41.67%)

tRNA,terminase,holin,transposase,portal,capsid,tail,head,integrase

attL 2784306:2784320|attR 2832258:2832272

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN48057.1\|2771582_2772779_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AUN48058.1\|2773088_2773412_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	3.0e-41	65.4
AUN48059.1\|2773514_2774765_-	isocitrate dehydrogenase (NADP(+))	Q77Z09	Phage_21	3.2e-22	96.3
AUN48060.1\|2774936_2775590_+	23S rRNA pseudouridine synthase E	NA	NA	NA	NA
AUN48061.1\|2775599_2776061_+	NUDIX hydrolase	NA	NA	NA	NA
AUN48062.1\|2776114_2777221_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
AUN50016.1\|2777256_2777898_+	lysogenization protein HflD	NA	NA	NA	NA
AUN48063.1\|2777901_2779272_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.2e-107	44.9
AUN48064.1\|2779440_2780112_+	two-component system response regulator PhoP	NA	NA	NA	NA
AUN48065.1\|2780111_2781572_+	sensor protein PhoQ	NA	NA	NA	NA
AUN48066.1\|2781647_2782769_+	50S ribosomal protein L16 arginine hydroxylase	NA	NA	NA	NA
AUN48067.1\|2782817_2784044_-	peptidase T	NA	NA	NA	NA
AUN50017.1\|2784099_2784315_+	hypothetical protein	NA	NA	NA	NA
AUN48068.1\|2784293_2785430_+	Fe3+/spermidine/putrescine ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
2784306:2784320	attL	NA	NA	NA	NA
AUN48069.1\|2785413_2786277_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
AUN50018.1\|2786873_2787500_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AUN48070.1\|2787444_2787582_-\|capsid	nucleocapsid protein	NA	NA	NA	NA
AUN48071.1\|2787737_2788268_-	chaperone of endosialidase	A0A2D1UII2	Escherichia_phage	2.5e-69	85.2
AUN48072.1\|2789001_2789373_-	hypothetical protein	NA	NA	NA	NA
AUN48073.1\|2789666_2791190_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.7e-44	31.8
AUN48074.1\|2795143_2795743_-	Ail/Lom family protein	H6WZM8	Escherichia_phage	1.6e-107	95.0
AUN48075.1\|2795810_2799290_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	89.9
AUN48076.1\|2799350_2799998_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.6e-108	94.4
AUN48077.1\|2799895_2800639_-	invasion associated endopeptidase	K7PLW1	Enterobacteria_phage	4.5e-149	97.2
AUN48078.1\|2800644_2801343_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	3.4e-130	97.0
AUN48079.1\|2801342_2801699_-\|tail	phage tail protein	A0A0P0ZDL9	Stx2-converting_phage	2.8e-40	66.7
AUN48080.1\|2801676_2804904_-\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	95.0
AUN50019.1\|2804950_2805211_-	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	2.3e-39	95.3
AUN48081.1\|2805252_2805639_-\|tail	phage tail protein	A0A1B5FP91	Escherichia_phage	8.9e-64	100.0
AUN48082.1\|2805638_2806343_-\|tail	phage tail protein	A0A1B5FP82	Escherichia_phage	1.4e-112	92.7
AUN48083.1\|2806403_2806748_-	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	5.1e-55	96.5
AUN48084.1\|2806744_2807194_-	hypothetical protein	S4TR46	Salmonella_phage	6.1e-64	81.2
AUN48085.1\|2807190_2807529_-\|head,tail	head-tail adaptor protein	A0A1B5FP90	Escherichia_phage	7.5e-51	90.2
AUN48086.1\|2807537_2807855_-\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	5.3e-22	49.5
AUN48087.1\|2807931_2809149_-\|capsid	phage major capsid protein	A0A1W6JP20	Morganella_phage	5.9e-162	71.6
AUN48088.1\|2809754_2810981_-\|portal	phage portal protein	Q8SBI0	Shigella_phage	3.7e-204	83.3
AUN48089.1\|2811128_2812886_-\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	99.3
AUN48090.1\|2812885_2813368_-\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	8.7e-85	98.1
AUN48091.1\|2813515_2813866_-	HNH endonuclease	A0A1B5FP94	Escherichia_phage	8.0e-64	96.6
AUN48092.1\|2814158_2814299_-	Rz1 lytic protein	U5P461	Shigella_phage	1.0e-09	84.6
AUN48093.1\|2814391_2814685_+	lipoprotein bor	K7PL54	Enterobacteria_phage	5.9e-44	90.7
AUN48094.1\|2814775_2814958_-	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	2.2e-17	77.0
AUN48095.1\|2815010_2815238_+	hypothetical protein	NA	NA	NA	NA
AUN48096.1\|2815174_2815708_-	lysozyme	Q08J98	Stx2-converting_phage	1.5e-98	93.2
AUN48097.1\|2815771_2816122_-	DUF1327 domain-containing protein	K7PGU6	Enterobacteria_phage	1.4e-36	94.0
AUN48098.1\|2816126_2816342_-\|holin	holin	A0A2R2Z340	Escherichia_phage	3.4e-33	98.6
AUN48099.1\|2816491_2816653_-	hypothetical protein	Q08JA2	Stx2-converting_phage	5.9e-14	87.0
AUN48100.1\|2816649_2816838_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	7.2e-27	95.2
AUN48101.1\|2816823_2816973_+	hydrogenase/urease nickel incorporation protein HypA	NA	NA	NA	NA
AUN48102.1\|2817098_2817434_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	1.4e-44	74.8
AUN48103.1\|2817504_2817717_+	hypothetical protein	NA	NA	NA	NA
AUN48104.1\|2818686_2819508_-	antitermination protein	K7P7B9	Enterobacteria_phage	5.1e-77	58.2
AUN48105.1\|2819504_2819885_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.6
AUN48106.1\|2819885_2820944_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	7.5e-89	48.0
AUN48107.1\|2820945_2821224_-	hypothetical protein	A0A077KB22	Edwardsiella_phage	6.1e-06	37.1
AUN48108.1\|2821391_2821604_-	Hok/Gef family protein	A0A0U2QV81	Escherichia_phage	8.9e-26	96.9
AUN48109.1\|2821806_2821986_-	hypothetical protein	NA	NA	NA	NA
AUN48110.1\|2822638_2822821_-	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
AUN48111.1\|2822914_2823271_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.8e-58	99.2
AUN48112.1\|2823328_2823751_-	DUF977 domain-containing protein	A0A0U2QQN3	Escherichia_phage	2.6e-64	90.6
AUN48113.1\|2823791_2824862_-	phage replisome organizer	A0A088CD36	Shigella_phage	2.6e-52	56.6
AUN48114.1\|2824933_2825359_-	Rha family transcriptional regulator	NA	NA	NA	NA
AUN48115.1\|2825342_2825585_-	hypothetical protein	H9C161	Pectobacterium_phage	4.8e-07	55.8
AUN50020.1\|2825790_2826315_+	LexA family transcriptional repressor	H9C160	Pectobacterium_phage	2.2e-12	28.0
AUN48116.1\|2826526_2826685_+	hypothetical protein	NA	NA	NA	NA
AUN48117.1\|2826668_2826968_+	hypothetical protein	NA	NA	NA	NA
AUN48118.1\|2827039_2827258_+	hypothetical protein	NA	NA	NA	NA
AUN48119.1\|2827222_2827477_-	hypothetical protein	NA	NA	NA	NA
AUN48120.1\|2827826_2828015_+	cell division inhibition protein DicB	NA	NA	NA	NA
AUN48121.1\|2828011_2828203_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AUN48122.1\|2828296_2830738_+	exonuclease	V5UQJ3	Shigella_phage	3.1e-114	46.9
AUN48123.1\|2830799_2831069_+	excisionase	NA	NA	NA	NA
AUN48124.1\|2831037_2832156_+\|integrase	integrase	Q77Z04	Phage_21	1.6e-84	44.4
2832258:2832272	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3405049 : 3463395

Escherichia_phage(15.38%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN48643.1\|3405049_3406162_-\|transposase	IS4 family transposase	NA	NA	NA	NA
AUN48644.1\|3406239_3406449_-	regulatory protein MokC	A0A0P0ZAX5	Stx2-converting_phage	8.0e-19	73.9
AUN48645.1\|3406491_3407861_-\|transposase	IS3-like element IS150 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.3e-112	100.0
AUN48646.1\|3408131_3408281_-	hypothetical protein	NA	NA	NA	NA
AUN48647.1\|3408292_3409411_+	glutamate--cysteine ligase	NA	NA	NA	NA
AUN48648.1\|3409548_3410253_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN48649.1\|3410337_3410700_+	hypothetical protein	NA	NA	NA	NA
AUN48650.1\|3410785_3411277_-	N-acetyltransferase	NA	NA	NA	NA
AUN48651.1\|3411447_3411705_-	transcriptional regulator	A0A2I7S995	Vibrio_phage	8.3e-18	65.7
AUN48652.1\|3411993_3412218_-	hypothetical protein	NA	NA	NA	NA
AUN48653.1\|3412303_3413272_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.4
AUN48654.1\|3413489_3415559_-	glycosyl transferase family 1	NA	NA	NA	NA
AUN48655.1\|3415562_3416753_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AUN48656.1\|3416800_3417955_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
AUN50041.1\|3417964_3418996_-	glycosyl transferase family 1	NA	NA	NA	NA
AUN48657.1\|3419061_3419814_-	O89/0101/0162 family O-antigen ABC transporter ATP-binding protein Wzt	W6JKT0	Anomala_cuprea_entomopoxvirus	1.1e-12	29.4
AUN48658.1\|3419820_3420528_-	ABC transporter	NA	NA	NA	NA
AUN48659.1\|3420567_3421272_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AUN48660.1\|3421450_3422104_+	NAD(P)H nitroreductase	NA	NA	NA	NA
AUN48661.1\|3422211_3423459_+	miniconductance mechanosensitive channel YbdG	NA	NA	NA	NA
AUN48662.1\|3423539_3424916_-	phenylalanine-specific permease	NA	NA	NA	NA
AUN48663.1\|3425017_3428161_-	cation efflux system protein CusA	S5VTK5	Leptospira_phage	2.2e-59	22.1
AUN48664.1\|3428172_3429396_-	cation efflux system protein CusB	NA	NA	NA	NA
AUN48665.1\|3429411_3429744_-	cation efflux system protein CusF	NA	NA	NA	NA
AUN48666.1\|3429901_3431275_-	cation efflux system protein CusC	NA	NA	NA	NA
AUN48667.1\|3431229_3431385_-	copper transporter	NA	NA	NA	NA
AUN48668.1\|3431431_3432115_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.0e-30	35.1
AUN48669.1\|3432104_3433547_+	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	3.0e-11	26.2
AUN48670.1\|3433696_3435934_+	type II secretion system protein E	NA	NA	NA	NA
AUN48671.1\|3435920_3438893_+	bacteriophage N4 adsorption protein A	NA	NA	NA	NA
AUN48672.1\|3438893_3439784_+	hypothetical protein	NA	NA	NA	NA
AUN48673.1\|3439697_3439910_-	hypothetical protein	NA	NA	NA	NA
AUN48674.1\|3439966_3440728_+	porin thermoregulatory protein EnvY	NA	NA	NA	NA
AUN48675.1\|3441092_3441725_+	DNA-binding response regulator	NA	NA	NA	NA
AUN48676.1\|3441727_3442243_-	fimbriae assembly protein	NA	NA	NA	NA
AUN48677.1\|3442253_3443294_-	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
AUN48678.1\|3443272_3445876_-	outer membrane usher protein SfmD	NA	NA	NA	NA
AUN48679.1\|3445906_3446599_-	fimbrial chaperone SfmC	NA	NA	NA	NA
AUN48680.1\|3446818_3447361_-	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
AUN48681.1\|3447831_3448698_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
AUN48682.1\|3448699_3448912_+\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
AUN48683.1\|3449019_3449541_+	metal-dependent hydrolase	NA	NA	NA	NA
AUN48684.1\|3449576_3450962_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	6.7e-45	34.5
AUN48685.1\|3451135_3451630_+	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
AUN48686.1\|3451632_3452355_+	UDP-2,3-diacylglucosamine hydrolase	NA	NA	NA	NA
AUN48687.1\|3452472_3452982_+	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
AUN48688.1\|3452978_3454046_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AUN48689.1\|3454240_3455134_-	carbamate kinase	NA	NA	NA	NA
AUN48690.1\|3455130_3455946_-	hypothetical protein	NA	NA	NA	NA
AUN48691.1\|3455956_3457216_-	DUF1116 domain-containing protein	NA	NA	NA	NA
AUN48692.1\|3457225_3458893_-	acyl-CoA synthetase FdrA	NA	NA	NA	NA
AUN48693.1\|3459209_3460259_+	ureidoglycolate dehydrogenase (NAD(+))	NA	NA	NA	NA
AUN48694.1\|3460280_3461516_+	Zn-dependent hydrolase	NA	NA	NA	NA
AUN48695.1\|3461526_3462312_+	(S)-ureidoglycine aminohydrolase	NA	NA	NA	NA
AUN48696.1\|3462426_3463395_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.4

DBSCAN-SWA_6

3714729 : 3767484

Morganella_phage(16.67%)

transposase,plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN48931.1\|3714729_3715185_+	hypothetical protein	A0A1W6JPI4	Morganella_phage	2.9e-45	66.4
AUN48932.1\|3715264_3715465_+	hypothetical protein	H6WRV2	Salmonella_phage	1.3e-05	43.1
AUN48933.1\|3715690_3715927_-	hypothetical protein	NA	NA	NA	NA
AUN50049.1\|3715948_3716386_+	hypothetical protein	I6S5X4	Salmonella_phage	3.1e-12	33.1
AUN48934.1\|3716448_3718554_-	injection protein	A0A2I7QQN9	Vibrio_phage	1.4e-86	36.2
AUN48935.1\|3718553_3720020_-	acyltransferase	B6SCW4	Bacteriophage	1.4e-106	53.3
AUN48936.1\|3720464_3720716_-	hypothetical protein	NA	NA	NA	NA
AUN48937.1\|3720782_3723539_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	2.6e-298	57.0
AUN48938.1\|3723551_3724154_-	hypothetical protein	Q8W653	Enterobacteria_phage	5.3e-23	34.7
AUN48939.1\|3724146_3724368_-	hypothetical protein	NA	NA	NA	NA
AUN48940.1\|3724364_3724628_-\|holin	nicotinic acetylcholine receptor subunit beta	NA	NA	NA	NA
AUN48941.1\|3724624_3724819_-	hypothetical protein	NA	NA	NA	NA
AUN48942.1\|3724811_3725879_-	ash family protein	NA	NA	NA	NA
AUN48943.1\|3725872_3726055_-	DUF4222 domain-containing protein	NA	NA	NA	NA
AUN48944.1\|3726047_3726857_-	antA/AntB antirepressor family protein	A0A0R6PJV6	Moraxella_phage	3.0e-29	53.6
AUN48945.1\|3726869_3727301_-	hypothetical protein	A0A1W6JPH9	Morganella_phage	3.0e-28	49.7
AUN48946.1\|3727300_3727504_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	4.7e-08	50.9
AUN48947.1\|3727551_3727785_+	excinuclease ABC subunit B	NA	NA	NA	NA
AUN48948.1\|3727896_3729111_-	DUF4102 domain-containing protein	Q7M297	Enterobacteria_phage	7.5e-133	56.5
AUN48949.1\|3729466_3730720_-	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	9.8e-96	47.2
AUN48950.1\|3730731_3731835_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
AUN48951.1\|3732122_3733178_+	outer membrane pore protein E	Q1MVN1	Enterobacteria_phage	2.0e-118	60.9
AUN48952.1\|3733216_3733618_-	sigma factor-binding protein Crl	NA	NA	NA	NA
AUN48953.1\|3733675_3734920_-	esterase	NA	NA	NA	NA
AUN48954.1\|3735011_3735470_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
AUN48955.1\|3735730_3737188_+	aminoacyl-histidine dipeptidase	NA	NA	NA	NA
AUN48956.1\|3737244_3737781_-	peptide chain release factor H	NA	NA	NA	NA
AUN48957.1\|3737713_3737980_-	hypothetical protein	NA	NA	NA	NA
AUN48958.1\|3737966_3738164_+	hypothetical protein	NA	NA	NA	NA
AUN48959.1\|3738285_3738738_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AUN48960.1\|3738747_3739146_-	mRNA interferase YafO	NA	NA	NA	NA
AUN48961.1\|3739148_3739442_-	antitoxin YafN	NA	NA	NA	NA
AUN48962.1\|3739493_3740549_-	DNA polymerase IV	NA	NA	NA	NA
AUN50050.1\|3740619_3741390_-	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
AUN48963.1\|3741349_3743089_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
AUN48964.1\|3743312_3743810_-\|transposase	transposase	NA	NA	NA	NA
AUN48965.1\|3743985_3744735_-	endopeptidase	A0A1V0DZX6	Clostridioides_phage	9.0e-20	38.5
AUN48966.1\|3744944_3745205_+	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
AUN48967.1\|3745207_3745486_+	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
AUN48968.1\|3745641_3746382_+	transpeptidase	NA	NA	NA	NA
AUN48969.1\|3746352_3747120_-	class II glutamine amidotransferase	NA	NA	NA	NA
AUN48970.1\|3747325_3747904_-	phosphoheptose isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
AUN48971.1\|3748143_3750588_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
AUN48972.1\|3750630_3751104_-	inhibitor of vertebrate lysozyme	NA	NA	NA	NA
AUN48973.1\|3751257_3752028_+	amidohydrolase	NA	NA	NA	NA
AUN48974.1\|3752068_3753205_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
AUN48975.1\|3753795_3754029_-	hypothetical protein	NA	NA	NA	NA
AUN48976.1\|3754006_3758239_-	RHS element protein	A0A2H4JHK7	uncultured_Caudovirales_phage	6.4e-22	43.1
AUN48977.1\|3758314_3760456_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.4e-25	25.0
AUN48978.1\|3760495_3760633_-	hypothetical protein	NA	NA	NA	NA
AUN48979.1\|3760665_3761184_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AUN48980.1\|3761878_3762379_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AUN48981.1\|3762413_3762638_+	hypothetical protein	NA	NA	NA	NA
AUN48982.1\|3762688_3764164_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AUN48983.1\|3764170_3764584_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AUN48984.1\|3764587_3766438_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
AUN48985.1\|3766401_3767484_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_7

4107646 : 4136358

Escherichia_phage(22.22%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN49285.1\|4107646_4109032_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.9e-257	89.1
AUN49286.1\|4109270_4110644_-	esterase-like activity of phytase	NA	NA	NA	NA
AUN49287.1\|4111007_4111217_+	hypothetical protein	A0A0N7BTS3	Escherichia_phage	5.9e-06	96.0
AUN49288.1\|4111379_4111637_-	biofilm development YmgB/AriR family protein	NA	NA	NA	NA
AUN49289.1\|4113387_4113909_+	RNA polymerase sigma factor FecI	NA	NA	NA	NA
AUN49290.1\|4113905_4114859_+	FecR family protein	NA	NA	NA	NA
AUN49291.1\|4114945_4117270_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
AUN49292.1\|4117314_4118217_+	Fe(3+)-dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
AUN49293.1\|4118213_4119212_+	iron-dicitrate transporter permease subunit	NA	NA	NA	NA
AUN49294.1\|4119208_4120165_+	iron-dicitrate transporter subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
AUN49295.1\|4120165_4120933_+	Fe(3+) dicitrate transport ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
AUN49296.1\|4121490_4121904_-	hypothetical protein	NA	NA	NA	NA
AUN49297.1\|4122398_4123922_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.7e-44	31.8
AUN49298.1\|4124215_4124653_+	hypothetical protein	NA	NA	NA	NA
AUN49299.1\|4125503_4126325_+	carbohydrate transporter	NA	NA	NA	NA
AUN49300.1\|4126327_4127416_+	colanic acid biosynthesis glycosyltransferase WcaL	NA	NA	NA	NA
AUN49301.1\|4127420_4128371_+	DUF535 domain-containing protein	NA	NA	NA	NA
AUN49302.1\|4128435_4129380_+	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
AUN49303.1\|4129560_4130700_+\|transposase	transposase	A0A0P0I4A4	Acinetobacter_phage	3.5e-68	45.1
AUN49304.1\|4130847_4132851_+\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	7.5e-21	25.9
AUN49305.1\|4132795_4132954_+\|holin	choline transporter	NA	NA	NA	NA
AUN49306.1\|4132913_4134191_+	DUF2254 domain-containing protein	NA	NA	NA	NA
AUN49307.1\|4134470_4135633_-\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.1e-51	40.6
AUN49308.1\|4135699_4135918_+	TetR family transcriptional regulator	NA	NA	NA	NA
AUN49309.1\|4135968_4136358_-\|transposase	transposase	A0A2L1IVB6	Escherichia_phage	1.9e-61	99.2

DBSCAN-SWA_8

4556751 : 4578309

Escherichia_phage(48.0%)

transposase,tail,integrase

attL 4553627:4553641|attR 4578391:4578405

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4553627:4553641	attL	NA	NA	NA	NA
AUN49676.1\|4556751_4558121_-\|transposase	IS3-like element IS150 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.3e-112	100.0
AUN49677.1\|4558193_4558448_-	transcriptional regulator	A0A0F7LDQ9	Escherichia_phage	6.1e-45	100.0
AUN49678.1\|4558493_4559657_-	hypothetical protein	U5N3V4	Enterobacteria_phage	4.8e-206	99.5
AUN49679.1\|4559656_4560136_-\|tail	phage tail protein	A0A0F7LDE8	Escherichia_phage	1.5e-84	99.4
AUN49680.1\|4560150_4562598_-\|tail	phage tail tape measure protein	M1T2S3	Escherichia_phage	0.0e+00	95.2
AUN50082.1\|4562590_4562710_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
AUN49681.1\|4562742_4563018_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	2.2e-40	98.9
AUN49682.1\|4563074_4563593_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
AUN49683.1\|4563605_4564796_-\|tail	phage tail protein	A0A0F7LBW9	Escherichia_phage	3.7e-225	99.7
AUN49684.1\|4564855_4565458_-	DNA-invertase	A0A0F7LA37	Escherichia_phage	3.5e-99	95.3
AUN49685.1\|4565465_4567001_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.5e-289	99.4
AUN49686.1\|4567049_4567397_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
AUN49687.1\|4567393_4567798_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
AUN49688.1\|4568118_4568865_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
AUN49689.1\|4568879_4570421_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.3e-129	46.4
AUN49690.1\|4571895_4572171_-	hypothetical protein	A0A0F7LCM4	Escherichia_phage	2.3e-45	100.0
AUN49691.1\|4572167_4572392_-	hypothetical protein	A0A0F7LDI3	Escherichia_phage	3.8e-35	98.6
AUN49692.1\|4572391_4572694_-	hypothetical protein	A0A0F7LDT6	Escherichia_phage	2.5e-45	96.0
AUN49693.1\|4572693_4572918_-	DUF2732 domain-containing protein	S4TP68	Salmonella_phage	4.7e-33	100.0
AUN50083.1\|4572981_4573482_-	replication protein B	M1SV55	Escherichia_phage	2.6e-92	100.0
AUN49694.1\|4573651_4573924_-	hypothetical protein	Q1JS36	Enterobacteria_phage	1.4e-47	100.0
AUN49695.1\|4574060_4574354_+	transcriptional regulator	Q1JS37	Enterobacteria_phage	2.7e-49	100.0
AUN49696.1\|4574423_4575404_+\|integrase	integrase	S4TP66	Salmonella_phage	4.7e-186	100.0
AUN50084.1\|4575590_4576091_-	periplasmic protein CpxP	NA	NA	NA	NA
AUN49697.1\|4576240_4576939_+	DNA-binding response regulator	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
AUN49698.1\|4576935_4578309_+	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	3.8e-16	25.9
4578391:4578405	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025626

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP025627

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection