CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP025615	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed3, complete sequence	0 crisprs	NA	0	0	9
CP025611	Niveispirillum cyanobacteriorum strain TH16 chromosome eg_1, complete sequence	0 crisprs	csa3,WYL,cas3,DinG,DEDDh	0	0	1
CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	0 crisprs	WYL,DEDDh,csa3	0	0	0
CP025612	Niveispirillum cyanobacteriorum strain TH16 chromosome eg_2, complete sequence	1 crisprs	csa3,cas2,cas1,cas4,cas7,cas8c,cas5,cas3	1	7	1
CP025614	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2736888 : 2792770

Stx2-converting_phage(28.57%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN31001.1\|2736888_2739018_-\|protease	ATP-dependent Zn protease	E5EQ50	Micromonas_sp._RCC1109_virus	1.8e-28	32.6
AUN31002.1\|2739303_2739873_-	hypothetical protein	NA	NA	NA	NA
AUN31003.1\|2739973_2741503_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	7.0e-19	24.8
AUN31850.1\|2741492_2742287_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.6e-33	35.3
AUN31004.1\|2742924_2744013_+	competence protein ComEC	NA	NA	NA	NA
AUN31005.1\|2744015_2744840_+	hypothetical protein	NA	NA	NA	NA
AUN31006.1\|2746596_2746944_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	1.0e-34	61.3
AUN31007.1\|2746940_2747357_-	hypothetical protein	NA	NA	NA	NA
AUN31851.1\|2748622_2749705_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AUN31008.1\|2750060_2750396_-	hypothetical protein	NA	NA	NA	NA
AUN31009.1\|2750488_2750650_+	hypothetical protein	NA	NA	NA	NA
AUN31010.1\|2750663_2751257_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AUN31011.1\|2751340_2751940_+	phenylacetic acid degradation protein PaaY	NA	NA	NA	NA
AUN31012.1\|2751962_2752712_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AUN31013.1\|2753098_2753401_-	EthD family reductase	NA	NA	NA	NA
AUN31014.1\|2753415_2754195_-	2,3-dehydroadipyl-CoA hydratase	NA	NA	NA	NA
AUN31015.1\|2754184_2755261_-	phenylacetate-CoA oxygenase/reductase subunit PaaK	NA	NA	NA	NA
AUN31016.1\|2755280_2755760_-	phenylacetate-CoA oxygenase subunit PaaJ	NA	NA	NA	NA
AUN31017.1\|2755764_2756520_-	phenylacetate-CoA oxygenase subunit PaaI	NA	NA	NA	NA
AUN31018.1\|2756530_2756815_-	1,2-phenylacetyl-CoA epoxidase subunit B	NA	NA	NA	NA
AUN31019.1\|2756895_2757876_-	1,2-phenylacetyl-CoA epoxidase subunit A	NA	NA	NA	NA
AUN31020.1\|2757979_2759182_-	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
AUN31021.1\|2759184_2759610_-	phenylacetic acid degradation protein PaaD	NA	NA	NA	NA
AUN31022.1\|2759602_2761066_-	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
AUN31023.1\|2761166_2761961_+	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase	NA	NA	NA	NA
AUN31024.1\|2761981_2763997_+	phenylacetic acid degradation bifunctional protein PaaZ	NA	NA	NA	NA
AUN31025.1\|2765224_2765860_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AUN31026.1\|2765976_2768163_+	TonB-dependent receptor	NA	NA	NA	NA
AUN31027.1\|2768223_2768601_+	cytochrome c family protein	NA	NA	NA	NA
AUN31028.1\|2768624_2769785_+	amine dehydrogenase	NA	NA	NA	NA
AUN31029.1\|2769788_2770316_+	hypothetical protein	NA	NA	NA	NA
AUN31852.1\|2770315_2770939_+	thiol-disulfide isomerase	NA	NA	NA	NA
AUN31030.1\|2770943_2771456_+	methylamine dehydrogenase (amicyanin) light chain	NA	NA	NA	NA
AUN31031.1\|2771460_2771913_+	cytochrome C	NA	NA	NA	NA
AUN31032.1\|2771946_2773356_+	aldehyde dehydrogenase	NA	NA	NA	NA
AUN31033.1\|2773352_2774648_+	phenylacetate--CoA ligase	NA	NA	NA	NA
AUN31853.1\|2774857_2774992_+	hypothetical protein	NA	NA	NA	NA
AUN31034.1\|2774988_2776713_+	amidohydrolase	NA	NA	NA	NA
AUN31035.1\|2776822_2779111_+	TonB-dependent receptor	NA	NA	NA	NA
AUN31036.1\|2779217_2780939_+	amidohydrolase	NA	NA	NA	NA
AUN31037.1\|2780954_2782064_+	class II histone deacetylase	A0A2K9KZC4	Tupanvirus	3.7e-38	34.0
AUN31854.1\|2782027_2782756_+	HD domain-containing protein	NA	NA	NA	NA
AUN31038.1\|2782736_2783660_+	hypothetical protein	NA	NA	NA	NA
AUN31039.1\|2784366_2784990_+	PAS domain-containing protein	NA	NA	NA	NA
AUN31040.1\|2785008_2786142_+	GGDEF domain-containing protein	NA	NA	NA	NA
AUN31041.1\|2786138_2787596_+	hypothetical protein	NA	NA	NA	NA
AUN31042.1\|2787675_2788722_+	GGDEF domain-containing protein	NA	NA	NA	NA
AUN31855.1\|2789086_2790661_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.4e-109	43.8
AUN31043.1\|2790731_2791085_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AUN31044.1\|2791081_2791435_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AUN31045.1\|2792016_2792770_+\|transposase	IS5/IS1182 family transposase	A0A0N9SJT9	Paenibacillus_phage	5.1e-15	42.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP025612

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CRISPR-Cas detection and classification

Crispr_ID: CP025612_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025612_2

1095835-1097897

TypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CRISPRCasFinder
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CRT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	PILER-CR

31 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of CP025612_2

>merge|CP025612|2|1095835-1097897|CRISPRCasFinder,CRT,PILER-CR
GTTTCAATCCGCGCCCCCGTCAAGGGGCGACCCTATCGGGTGGCAATTGGCTTTCCCAGCACTGGTTTCAATCCACGCTCCCGTGAAGGGGCGACCTGCCGTGACGCTGGCGCAGGCCAAGGCAGAAATCGTTTCAATCCACGCCCCCGTGAAGGGGCGACCGCGGCGGTTCTTCAACCTGGGCGTTTCTGGCCTGTTTCAATCCACGCCCCCGTGAAGGGGCGACTGCAACCAGCATCCCGCGCCGCCTGCTCCGATCTGTTTCAATCCACGCCCCCGTGAAGGGGCGACCCGGTCGTTAAGGGGTTAGAGGCCCTTTTCAATATGTTTCAATCCACGCCCCCGTGAAGGGGCGACCATCGATAGAGGATAAGACGGGCAACCGGTCAGCGTTTCAATCCACGCCCCCGTGAAGGGGCGACATCAGCGCGGGCCGCAGGTTACCGGCGGCATTGACGTTTCAATCCACGCCCCCGTGAAGGGGCGACACCACCACCGTCACCAGATGGGTAGCCTGGCGTGGCCGTTTCAATCCACGCCCCCGTGAAGGGGCGACTCGTTCTTGACGTTGTCCAGCGGCATTGACGCCACGTTTCAATCCACGCCCCCGTGAAGGGGCGACGTCTGGCCGGGCAAGGCCAGATCCATTAGACGACGTTTCAATCCACGCCCCCGTGAAGGGGCGACTTTCACGGGTCGGGCGGAGCCTGGTGCTCGCGTGGGTTTCAATCCACGCCCCCGTGAAGGGGCGACCTTCGCCCAGATCCGGCAGTTCCGGGCCAAGTTCAAGGTTTCAATCCACGCCCCCGTGAAGGGGCGACGCCATCCTGTCACCGATTGCCCCGCGGACTTACCAGTTTCAATCCACGCCCCTGTGAAGGGGCGACTCGTGATAACGTTGACCGCTGGACGGCAGCCGCCGCTGTTTCAATCCACGCCCCCGTGAAGGGGCGACGATAGCCTCTTGCAGTTGATCGGCGCGCAACGATGTTTCAATCCACGCCCCCGTGAAGGGGCGACGGAATGGGCGAGGTGACCTCCTCCACCCGCGCATAGTTTCAATCCACGCCCCCGTGAAGGGGCGACATGCCGACACCCAGCGCTAGGCAGCACAGCGCGACGTTTCAATCCACGCCCCCGTGAAGGGGCGACCAGCCCAGGCCGGCGGGCACACGTGAAGCGAGCGTTTCAATCCACGCCCCCGTGAAGGGGCGACCGGTGCAGGCATCATCTTCCGCCGGTCTGGCCCTGTTTCAATCCACGCCCCCGTGAAGGGGCGACTTGCCCAAGGTAGCTGCTGCTACCAGCGTCTGCGTGTTTCAATCCACGCCCCCGTGAAGGGGCGACTGTAGTTCGGCGGCACGCGGCCAGCGTCCACCGTGTTTCAATCCACGCCCCCGTGAAGGGGCGACTTTCGATAGGGTTGCCGTAGTTCCAGATTTCAATGTTTCAATCCACGCCCCCGTGAAGGGGCGACTTGGCGGTCAGCCTTGTCCTGGGTTACGCTTCGGACGTTTCAATCCACGCCCCCGTGAAGGGGCGACCGTGTCCAGACTGCGCAGCCCCTCGATCACGCTGTTTCAATCCACGCCCCCGTGAAGGGGCGACTGCAAACCGCATTCCGCGATGCCTTGGCGCGACAGTTTCAATCCACGCCCCCGTGAAGGGGCGACCCTACCGTATATCCCGGCAGCTTTACAGGGGCGGTTTCAATCCACGCCCCCGTGAAGGGGCGACACATGATTGCGCATCGTGTCGAAATGGATCAGATTGTTTCAATCCACGCCCCCGTGAAGGGGCGACCGCTGTCATAGGGATGGACGGCGCCACCGCCATGGTTTCAATCCACGCCCCCGTGAAGGGGCGACTTTGCAGGCAACGCACAAAGCAGTGGGGGCTGCGGTTTCAATCCACGCCCCCGTGAAGGGGCGACCTTCGCGTGTCCATCCACGCCGCGAGACTGAACTGTTTCAATCCACGCCCCCGTGAAGGGGCGACCCAATATCAACGTAACGATAGGACAATGACCATGGTTTCAATCCACGCCCCCGTGAAGGGGCGAC

>CP025612|2|1|1095835-1097897|CRISPRCasFinder
GTTTCAATCCGCGCCCCCGTCAAGGGGCGAC	CCTATCGGGTGGCAATTGGCTTTCCCAGCACTG
GTTTCAATCCACGCTCCCGTGAAGGGGCGAC	CTGCCGTGACGCTGGCGCAGGCCAAGGCAGAAATC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGCGGCGGTTCTTCAACCTGGGCGTTTCTGGCCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGCAACCAGCATCCCGCGCCGCCTGCTCCGATCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCGGTCGTTAAGGGGTTAGAGGCCCTTTTCAATAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CATCGATAGAGGATAAGACGGGCAACCGGTCAGC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ATCAGCGCGGGCCGCAGGTTACCGGCGGCATTGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ACCACCACCGTCACCAGATGGGTAGCCTGGCGTGGCC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TCGTTCTTGACGTTGTCCAGCGGCATTGACGCCAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GTCTGGCCGGGCAAGGCCAGATCCATTAGACGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTCACGGGTCGGGCGGAGCCTGGTGCTCGCGTGG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CTTCGCCCAGATCCGGCAGTTCCGGGCCAAGTTCAAG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GCCATCCTGTCACCGATTGCCCCGCGGACTTACCA
GTTTCAATCCACGCCCCTGTGAAGGGGCGAC	TCGTGATAACGTTGACCGCTGGACGGCAGCCGCCGCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GATAGCCTCTTGCAGTTGATCGGCGCGCAACGAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GGAATGGGCGAGGTGACCTCCTCCACCCGCGCATA
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ATGCCGACACCCAGCGCTAGGCAGCACAGCGCGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CAGCCCAGGCCGGCGGGCACACGTGAAGCGAGC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGGTGCAGGCATCATCTTCCGCCGGTCTGGCCCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTGCCCAAGGTAGCTGCTGCTACCAGCGTCTGCGT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGTAGTTCGGCGGCACGCGGCCAGCGTCCACCGT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTCGATAGGGTTGCCGTAGTTCCAGATTTCAAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTGGCGGTCAGCCTTGTCCTGGGTTACGCTTCGGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGTGTCCAGACTGCGCAGCCCCTCGATCACGCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGCAAACCGCATTCCGCGATGCCTTGGCGCGACA
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCTACCGTATATCCCGGCAGCTTTACAGGGGCG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ACATGATTGCGCATCGTGTCGAAATGGATCAGATT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGCTGTCATAGGGATGGACGGCGCCACCGCCATG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTGCAGGCAACGCACAAAGCAGTGGGGGCTGCG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CTTCGCGTGTCCATCCACGCCGCGAGACTGAACT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCAATATCAACGTAACGATAGGACAATGACCATG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC

>CP025612|2|1|1095835-1097897|CRT
GTTTCAATCCGCGCCCCCGTCAAGGGGCGAC	CCTATCGGGTGGCAATTGGCTTTCCCAGCACTG
GTTTCAATCCACGCTCCCGTGAAGGGGCGAC	CTGCCGTGACGCTGGCGCAGGCCAAGGCAGAAATC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGCGGCGGTTCTTCAACCTGGGCGTTTCTGGCCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGCAACCAGCATCCCGCGCCGCCTGCTCCGATCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCGGTCGTTAAGGGGTTAGAGGCCCTTTTCAATAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CATCGATAGAGGATAAGACGGGCAACCGGTCAGC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ATCAGCGCGGGCCGCAGGTTACCGGCGGCATTGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ACCACCACCGTCACCAGATGGGTAGCCTGGCGTGGCC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TCGTTCTTGACGTTGTCCAGCGGCATTGACGCCAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GTCTGGCCGGGCAAGGCCAGATCCATTAGACGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTCACGGGTCGGGCGGAGCCTGGTGCTCGCGTGG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CTTCGCCCAGATCCGGCAGTTCCGGGCCAAGTTCAAG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GCCATCCTGTCACCGATTGCCCCGCGGACTTACCA
GTTTCAATCCACGCCCCTGTGAAGGGGCGAC	TCGTGATAACGTTGACCGCTGGACGGCAGCCGCCGCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GATAGCCTCTTGCAGTTGATCGGCGCGCAACGAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GGAATGGGCGAGGTGACCTCCTCCACCCGCGCATA
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ATGCCGACACCCAGCGCTAGGCAGCACAGCGCGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CAGCCCAGGCCGGCGGGCACACGTGAAGCGAGC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGGTGCAGGCATCATCTTCCGCCGGTCTGGCCCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTGCCCAAGGTAGCTGCTGCTACCAGCGTCTGCGT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGTAGTTCGGCGGCACGCGGCCAGCGTCCACCGT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTCGATAGGGTTGCCGTAGTTCCAGATTTCAAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTGGCGGTCAGCCTTGTCCTGGGTTACGCTTCGGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGTGTCCAGACTGCGCAGCCCCTCGATCACGCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGCAAACCGCATTCCGCGATGCCTTGGCGCGACA
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCTACCGTATATCCCGGCAGCTTTACAGGGGCG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ACATGATTGCGCATCGTGTCGAAATGGATCAGATT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGCTGTCATAGGGATGGACGGCGCCACCGCCATG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTGCAGGCAACGCACAAAGCAGTGGGGGCTGCG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CTTCGCGTGTCCATCCACGCCGCGAGACTGAACT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCAATATCAACGTAACGATAGGACAATGACCATG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC

>CP025612|2|2|1095899-1097897|PILER-CR
GTTTCAATCCACGCTCCCGTGAAGGGGCGAC	CTGCCGTGACGCTGGCGCAGGCCAAGGCAGAAATC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGCGGCGGTTCTTCAACCTGGGCGTTTCTGGCCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGCAACCAGCATCCCGCGCCGCCTGCTCCGATCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCGGTCGTTAAGGGGTTAGAGGCCCTTTTCAATAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CATCGATAGAGGATAAGACGGGCAACCGGTCAGC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ATCAGCGCGGGCCGCAGGTTACCGGCGGCATTGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ACCACCACCGTCACCAGATGGGTAGCCTGGCGTGGCC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TCGTTCTTGACGTTGTCCAGCGGCATTGACGCCAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GTCTGGCCGGGCAAGGCCAGATCCATTAGACGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTCACGGGTCGGGCGGAGCCTGGTGCTCGCGTGG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CTTCGCCCAGATCCGGCAGTTCCGGGCCAAGTTCAAG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GCCATCCTGTCACCGATTGCCCCGCGGACTTACCA
GTTTCAATCCACGCCCCTGTGAAGGGGCGAC	TCGTGATAACGTTGACCGCTGGACGGCAGCCGCCGCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GATAGCCTCTTGCAGTTGATCGGCGCGCAACGAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	GGAATGGGCGAGGTGACCTCCTCCACCCGCGCATA
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ATGCCGACACCCAGCGCTAGGCAGCACAGCGCGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CAGCCCAGGCCGGCGGGCACACGTGAAGCGAGC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGGTGCAGGCATCATCTTCCGCCGGTCTGGCCCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTGCCCAAGGTAGCTGCTGCTACCAGCGTCTGCGT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGTAGTTCGGCGGCACGCGGCCAGCGTCCACCGT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTCGATAGGGTTGCCGTAGTTCCAGATTTCAAT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTGGCGGTCAGCCTTGTCCTGGGTTACGCTTCGGAC
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGTGTCCAGACTGCGCAGCCCCTCGATCACGCT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TGCAAACCGCATTCCGCGATGCCTTGGCGCGACA
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCTACCGTATATCCCGGCAGCTTTACAGGGGCG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	ACATGATTGCGCATCGTGTCGAAATGGATCAGATT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CGCTGTCATAGGGATGGACGGCGCCACCGCCATG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	TTTGCAGGCAACGCACAAAGCAGTGGGGGCTGCG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CTTCGCGTGTCCATCCACGCCGCGAGACTGAACT
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC	CCAATATCAACGTAACGATAGGACAATGACCATG
GTTTCAATCCACGCCCCCGTGAAGGGGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP025612.1\|AUN32681.1\|1080783_1082115_-\|multidrug-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|274576
CP025612.1\|AUN32684.1\|1083480_1084832_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
CP025612.1\|AUN32687.1\|1099438_1100053_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
CP025612.1\|AUN32694.1\|1108040_1109237_+\|hypothetical-protein	unknown	unknown	unknown
CP025612.1\|AUN32920.1\|1085222_1086485_+\|integrase	unknown	unknown	gnl\|CDD\|271177
CP025612.1\|AUN32921.1\|1086740_1092833_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225483
CP025612.1\|AUN32679.1\|1079955_1080252_-\|hypothetical-protein	unknown	unknown	unknown
CP025612.1\|AUN32689.1\|1101029_1102856_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
CP025612.1\|AUN32693.1\|1106822_1107644_+\|IS5/IS1182-family-transposase	unknown	unknown	gnl\|CDD\|379129
CP025612.1\|AUN32678.1\|1079243_1079948_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378067
CP025612.1\|AUN32686.1\|1098393_1099434_-\|subtype-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
CP025612.1\|AUN32691.1\|1103567_1105850_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
CP025612.1\|AUN32688.1\|1100081_1101026_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
CP025612.1\|AUN32690.1\|1102852_1103551_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
CP025612.1\|AUN32922.1\|1094976_1095735_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
CP025612.1\|AUN32685.1\|1098090_1098381_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP025612.1\|AUN32692.1\|1106369_1106621_-\|hypothetical-protein	unknown	unknown	unknown
CP025612.1\|AUN32680.1\|1080274_1080778_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378700
CP025612.1\|AUN32683.1\|1082900_1083224_-\|hypothetical-protein	unknown	unknown	unknown
CP025612.1\|AUN32682.1\|1082111_1082777_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222

Protein	Function_ID	Function_description	E-value
CP025612.1\|AUN32681.1\|1080783_1082115_-\|multidrug-ABC-transporter-substrate-binding-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	3.82585e-16
CP025612.1\|AUN32684.1\|1083480_1084832_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	4.38037e-33
CP025612.1\|AUN32920.1\|1085222_1086485_+\|integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.75342e-29
CP025612.1\|AUN32680.1\|1080274_1080778_-\|hypothetical-protein	gnl\|CDD\|378700	pfam11736, DUF3299, Protein of unknown function (DUF3299). This is a family of bacterial proteins of unknown function.	5.55799e-07
CP025612.1\|AUN32921.1\|1086740_1092833_-\|hypothetical-protein	gnl\|CDD\|225483	COG2931, COG2931, RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism].	2.64473e-14
CP025612.1\|AUN32689.1\|1101029_1102856_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
CP025612.1\|AUN32693.1\|1106822_1107644_+\|IS5/IS1182-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.7239e-28
CP025612.1\|AUN32678.1\|1079243_1079948_+\|hypothetical-protein	gnl\|CDD\|378067	pfam08856, DUF1826, Protein of unknown function (DUF1826). These proteins are functionally uncharacterized.	1.10031e-38
CP025612.1\|AUN32688.1\|1100081_1101026_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.89337e-147
CP025612.1\|AUN32691.1\|1103567_1105850_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	5.05603e-58
CP025612.1\|AUN32690.1\|1102852_1103551_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.26011e-103
CP025612.1\|AUN32922.1\|1094976_1095735_+\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	2.71468e-56
CP025612.1\|AUN32685.1\|1098090_1098381_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.99617e-32
CP025612.1\|AUN32687.1\|1099438_1100053_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	2.22054e-47
CP025612.1\|AUN32686.1\|1098393_1099434_-\|subtype-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
CP025612.1\|AUN32682.1\|1082111_1082777_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.19364e-65

>CP025612.1|AUN32922.1|1094976_1095735_+|ATP-binding-protein
MLRSLKMYGLAQAVTDVIEQGAPAFEAAISILNQLLKAEMAEREVRSIAYHMKATRFPAYKDLAGFDFQASEINEATVCQLHSCAFIDGARNVVLIGGPGTGKTHVATAIAIQAIEHHRRKARFISAIELVNALEQEKTKGKAGQLAEAMTRLDLVILDELGYPPFSASGGALLFHLLSKLYEWTSVIITTNLSFSEWATVFGDAKMTTALLDRLTHRCHIVETGNDSFRFKASTAAASAKRKGNPHALTQP
>CP025612.1|AUN32921.1|1086740_1092833_-|hypothetical-protein
MSVAAGNSVYASTLFETQTDGAGPGRPGGEHTLQLVEFTDSAVGGGHFLLNGIEQASNTPFSVAADELYRVQWVAGAAAGSEQVQIRAFDGDHWSAPIISTITSTLTSPVQLVQTEHAANANVAGAQALPKIAILPDNSYIVVWEAAIGDASGSGILLQRHDAEGNRIGAEVLVNTYVTSDQKYPAITVLANGDYVVTWSSNGQDTSSWGVYARRYAADGTALGGEFRVNSTIAGGQYTSDVVALADGGFAVAFVHSVATTPAVDTDIRIRFWDSSGTARGPDFRINSYTTAQQREVDLAVGSDGKVLAVWHSENQDGSGYGIYGRLLSADGNLAGPEFQISQYTANDQALPAVAALKGGGYVVTWGSSGQVEGSQAVIAQRIDSHGNLVGGEFIVNTYQPNAQSQPAVTALADGGFLIAWQSMGQDDFGLGLYGQRYDASGAAIGSEFAINQRNSGIQQKVALDARTDGGWIAVWETERSDGLMTTASRIWAPTNTIPVLAATDTTIAVNGKLNAVTLFDLLQDPAGGGRPAGDHDIVNFEFTDLAADGGYFTVNGITQASGTPFTVSADQLATVAWVAAPAAGTEQVQVRAFDGVNWSSAVTTDITSFVPTTMVVVPGNVPVNSHTTQDQSAPSVAVLAGGGHVVVWQSSGQDGSGLGIYQQRFDAAGNPMGGEARINTTTADNQHDAKVTALTNGGYVVSWSSLNEDGSGNGVYARFYDGGGTPQGTPFLTHVNTTFSQFHSDVTEVADGLVYFIYTHTVATGDSDIYVRGFLVDGTAASPEMKLNQFSTGFQNNPAIASLGNGNALAVWQSESQDGSGFGIYGRILLSNKNIPAGEFVINSTTADNQSIPAVTALVGGDYLVAWASQSQDGSAAGIYAQRIDLTGNKVGGEFQVNTHTAGAQNAASVTALSDGGWLISWQSDGQDGSGLGVYGQRYDANGNPVNGEFRISETTAGDQGQPAVAARLDGGWVAAFVAADSSGTGIYTRLYSDPSQLPNGFYEQWGTSGDDILTGTPYRDRLMGLDGNDILSGLADSDLLDGGNGDDVLDGGLGADTMVGGAGDDTYVVDDSGDVVTEAVGAGVDTINATAAAVTLSANVENLYFVGTGNFTATGNNLTNLIQGGAGNDTLDGGAGADTLHGGTGNDTFIVDNIGDQIVEWSGAGTDTVRTSLSAYTLGDQLENLTYSGSGNFTGAGNGAANNITGGAGNDTLTGGSGADTLVGGAGDDLYTVEETGDVVIEGAGGGMDHVRALANAYTLSAEIENLSFIGSGDFAGIGNGLANSITGGSDNDTLDGGAGADTLAGGLGDDTYVVDDAGDVIEDAGGVETVRTSLTAYALAANLEHLAYIGTGNFAGTGNGGGNSITGGSGNDTLDGGTGADTLAGGAGNDVYFVDDAGDVVVEGVSQGTDRVETALSSLTLAANIENLTYTGGGDFAGTGNSSANSIKGGAGTDTLDGQAGNDTLDGGAGADNMIGGLGNDTFIVDDAGDVVVETAGQGTDTVRTSLSVYTLGSDIENLVFTGTSGFLGIGTAANNSITGGSGNDTLEGLDGNDTLVGGNGDDSLTGGDGNDSLSGSAGADTLTGGLGNDIYVVDNVGDVVVEALGEGTDTVQSSISYVLDGTLENLTLTGGVAINGTGNDGDNVLTGNGAANSLEGGLGNDTLNGGAGADTMAGGAGDDAYTVDNGGDIVNELADEGTDQVQASVSYTLTANVENLTLTGTGAIDGTGNDLANILTGNSGANLLDGGAGADTMAGGTGNDIYVVADVGDVVNEATGQGTDAVRTDLAAYILTANVENLTYTGTGDFAGTGNGSGNLLIGGIGADTLYGLDGNDTLDGGAGADSLVGGAGDDTYIVDDAGDVVSEAAGEGIDNVQTSLSAYTLTANVENLAYTGTDDFAGTGNDLGNVIAGSSGNDTLDGGIGADTLTGGAGADLFIVGNSDMVSDFSAGDGDRIDLSAIDADASLPGDDAFTWLDGAAFSNVAGQLRWETVGADIALLADLDGDGVADLTVSVAGITSITAAELVL
>CP025612.1|AUN32920.1|1085222_1086485_+|integrase
MAKLSKRSVDRAAAGPTLKVVWDDELRGFGVRIHPTGRKVYIVKCRINGQQRFITIGQHGPVTAEHARARAYEILSEAKNGRDPAQELDQGRKAPTMKALGERFLEEHVAVRCKPSTQYEYRRSVELFINPKIGTRRVTDIQRWDIAELHHSLRHIPYQANRTLGVLSKMFNLAEVWGLRPDGSNPCLHVKKFPEEKRERFLSADEYAALGRTLAELEAAKSEPVSVIAAIRLLMLTGCRLGEIMTLKWAYVDWQAKAFRLPDSKTGAKVVLFGDSVAAILHAIPKLPNNQWVITGTKEGARLTDLQPPWRRVRGRAGLDDVRLHDLRHFFASGALFLGEGLPMIGKLLGHTQVQTTARYAHLALDPVRSAVEKVSGFIAKQAAGSSRSNYTRRSRFRIVARTQLPDTLDHNDAAKLAID
>CP025612.1|AUN32684.1|1083480_1084832_-|IS3-family-transposase
MRQKSMAPTSVAEQVVRDIRRQTRKHYSAEEKIRIVLSGRRGEDSIAELCRREGIAESLYYSWSKEFLEAGKKRLSGDTARQASTGEVKDLRREVRDLKEVVADLTLENRPLKKKHDRGWGRRGMRYPASEKLEIIRLVEASHLPLRRTLDRLGIPATTFYRWYARYRAEGEGGLADRTSAPGRVWNRIPDEVRQQLIELALEAPDLSPRELAVKFTDTRGYFVSEASVYRLLKAHNLITSPAFVVIKAADEFRDKTTRPNQMWQTDFTYLKVIGWGWFYLSTILDDYSRYIVAWKLCTTMRAQDVTDTLTLALEASGCDQVEITHKPRLLSDNGSSYIAGDLAEWLDDKGMDHVRGAPNHPQTQGKIERWHQTLKNRSLLENYFLPGDLEAKILGFVDHYNHRRYHESIGNLTPADVYYDRGSAILERRAKIKKQTIQHRRLCHQSQAA
>CP025612.1|AUN32683.1|1082900_1083224_-|hypothetical-protein
MVPNDTILGACSWRSARHAVCHHAFHTGFVEAMSGKPFDYAALDAMTEYEQHRYENGRELAWECRQARLTIRWTRRDAVPRALRDFVTSRALRRRAGLPRTDPYRAR
>CP025612.1|AUN32682.1|1082111_1082777_-|ABC-transporter-ATP-binding-protein
MPTANLIDLNDVVHHASGQPILSVARLCLPPGHHGLLLGPSGSGKTTLLHALAGLLVPHQGRLSLLGHDLRAIGDAGRDRLRADHVGIVFQQLHLIHAVSIADNLRLARRLAGKAPDEKGLKELLIRVGLADRMSALPADLSQGERQRVAVARALVNQPALLLADEPTSALDDANCDGVIDLLLEQAALSGATLLVATHDRRLMSRLPVLLELVKPMERAA
>CP025612.1|AUN32681.1|1080783_1082115_-|multidrug-ABC-transporter-substrate-binding-protein
MNMLGLSLAYLRRRPLTTGLNLLLLALGVALIAFLLLLERGLENRLSRDVAGIDMVVGAKGSPLQLVLSAVMQVDVPTGNVPLAAVEELRRNPLVRQAIPVAMGDSYGTYRILGTEPAYIAHYGGHVVTGRMFEAPMEAVLGAEVAASSGLGLDSALVGSHGLTAGGDAHADMPYRVVGILARTGTVLDRLVLTPVSSVWAVHDHHHHEDKAPATTGEHADGKAHDHGAEAAHDHDHDHDHDHGHHHDHDHDDVAAGQADSDDREVTAILVRYATPLAAARLPREINSQTSMQAASPAAEMLRLRALMGVGLDSMRLLGLVLVLAAGLSTFVALANALQERQYDLAVMRALGAGRGRIMGQILTEAMLVALGGAVLGIALAHAGVAALSGFSARARDLGLSAGQFVAGEAWLLGLSLLVALLAAAVPAIRAYRTDVSRLLAKG
>CP025612.1|AUN32680.1|1080274_1080778_-|hypothetical-protein
MKTVKIALLLAILGGAMPALAFKQVQDPAMASQAIPHDPRAVPRATLGWDKLADTKETQKRVQEVNRLIAVFGPGVKSLDGQPFTVAGFFLPLDTGETSRSFLLSSLAPTCPFCPPPGPADLIQVSAAEPVTATLDQVTLEGTLRLSAEDVNGIYFHLENARVVPKS
>CP025612.1|AUN32679.1|1079955_1080252_-|hypothetical-protein
MLLWTTGPALAQESCGKLYQNQDCGAAEYEEALARQKEMEAKLKQQAPPEAPVPGGTAETDTRDMRQRALDLYRARAAAMANSVQCCHPGVDGTLWCH
>CP025612.1|AUN32678.1|1079243_1079948_+|hypothetical-protein
MPGSVCPTPSPAGSGRGRRDVAVIVSNPLVRGADASVLSDIQNPDVSLAVWDRSPPRLLLEGMAGLCPGHLPQGRVLVWLPDAPAALSGILAETPIGATMLGRSLVDDMLMLVKRFATIAGTDIVDIRLDRLRHDACWKFHRDQVRLRLLTTYRGPATQIVPQTHAEQALRDQRAYLGPLEDLPDGAVALFKGLQAGPDTGVVHRSPPISGTGTVRSLLCLNLPSDTSPRLWEP
>CP025612.1|AUN32685.1|1098090_1098381_-|CRISPR-associated-endonuclease-Cas2
MLMLITYDVRTEDTAGRRRLRRVARACQDFGQRVQFSVFECEVEPAQWVALRARLVGEIDPTVDSLRFYHLGANAARRIEHVGAKPAQDFDAPLIF
>CP025612.1|AUN32686.1|1098393_1099434_-|subtype-I-C-CRISPR-associated-endonuclease-Cas1
MRQHLNTLFVTTEGSWLRKDGANIVVEVEGQERGRVPAHMMGGVVCFGRVAMSPALMGFCAEQGIGVSFLSEHGKFIARVEGAQSGNVLLRRRQYRLADDPVVSAVIAGSIVAGKVANQRTVLRRALRDHGSNMAPDQAAAIDDAQRRLADAARLAAETTDLDRVRGLEGEGASAYFGVFDHLIRAAAPELRFRGRSRRPPLDVPNALLSFLYAILGHDCRSALEVVGLDPQVGFLHRDRPGRAGLALDLMEELRPLLADRVALSLLNRGQLTAKDFEWHDGGAVMLRDDARKTVLATYQERKRQELLHPFLEEKITIGLIAHIQARLLARHLRGDLDRYPPFLWK
>CP025612.1|AUN32687.1|1099438_1100053_-|CRISPR-associated-protein-Cas4
MENDDPIPLSALQHWLFCPRQCALIHLERQWAENAATADGRILHERADQPGRTRRGEVRTLRALPLRCHRLNLVGVADVVELRGGIPFPVEYKRGRPKSHRADEVQLCAQALCLEEMFDQPVSQGALFYGETRRRTEIVFDADLRALTVQVAAEIAAMLNSGTTPPPAFEARKCGQCSLIDLCQPRPLAHHPDVAGWLRRQLRD
>CP025612.1|AUN32688.1|1100081_1101026_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSALNNRYEFVFLFDVTNGNPNGDPDAGNLPRLDPETNHGLVTDVCLKRKIRNFVGLFHEGEPGKGIYVQEGAILNEKHREAYKAVRPGDADVATAKKLTPKGDEEEKAVRQFMCDNFFDVRTFGAVMGTGINCGQVRGPVQFAFAQSVEPVLPLEISITRMAATTEGEKKEGEAEGARRENRTMGRKHIIPYGLYRAHGYISAKLAEKTGFSQDDLDLLWSALEQMFDHDRSAARGEMGSRKLILFKHASALGNAAAPGLFDRVQVLRRHAGSEVPVKDPRTDNWPPARSFADYAVTINREGLPAGVEIIERF
>CP025612.1|AUN32689.1|1101029_1102856_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTILAALNRHYDRLLAEGAAPPFGFSTEGIGFCLVLNRDGTLSRPPDDLRGTDKKRPPTPMPVPASFKRPGVTPRAFFLWDNTKFVLGLGKDKASGGIAAYPAHLAAFREKHEAALGQSNDPGLQALLCFLRSWNPDSFSDQGWDTDILDQNIIFALDEDYPGQFLHERPTAQEIWRRELAATASDKQMCLVTGEQAPAARLHPAIKGVWGAQSSGASLVSFNLDAFTSYAKEQGGNAPVSEAASFGYGTALNALLAKGSDNRVQVGDASVAFWADASGIAAAREAEALAGAALAPRFADEDDDIPTDAQEARKVRDALEKLAKGMPVERASVTVDPGTRFYILGLAPNAARLSVRFWQETTLGNFASALRWHWSDLRLDPPAWKGEPRLQALLYQTAVQDKAENIPPLLGGELMRAVLNPNCRYPRTLLSAVLQRIRADGDIRPARAAIVKAWLARDARIAAPEKHETPEKEELYVSLDREETNPAYRLGRLFAVLESIQYRALGSVNASIRDRYFGAASATPSAVFPLLLRGSNHHLSVLRKKPETKRLAGWFEGQVGEIMDGLATTLPRHFGLEDQGRFVVGYYHQRSERSSKTAEEAGHQGQED
>CP025612.1|AUN32690.1|1102852_1103551_-|type-I-C-CRISPR-associated-protein-Cas5
MPFGVKLRVRGDFACFTRPEMKVERVSYDVLTPSAARGILEAVHWKPAITWVVDRIHVLKPIQFMSIRRNEVASKVPVAKVKQAMKAGHVTDLYTRADQDRQQRAATLLRDVDYIIEAHFEMTDRAGPDDNPAKHMDIFNRRAAAGQCFQQPCFGSREFPASFELWTGPVPAHSLPTEQADKDLGWMLLDMDHHGDPGGHRCDDRCVPLFFRAQLLGGVLRVPDRQSGEVRS
>CP025612.1|AUN32691.1|1103567_1105850_-|CRISPR-associated-helicase/endonuclease-Cas3
MLYAHSSRAGDYESWEPLVTHLLAVAELAQRFATPFGFGMAGRALGLLHDVGKMAEAYQLYIKGQGPSPDHSTAGAVIACDRYGKTWGPLLAGGIAGHHAGLADGDGVQGELTPLKSRLERFKGDKRWPEGVEPPPAELVRKSLKHLDSGFRRSLLGRMLFSCLIDADRLATEAFYAHLNQQQVQRGCDSDVAMLRDRLAEHLEGLSARARADVTADPALGPVNALRARVLDHVLSQAEQEPGLFSLTVPTGGGKTLVSLAFALNHAVRWGKRRVIYVIPFTSIVEQTADVFRKALGDDDAVLEHHSGFDPARDWQDARDKDAEGRDGGTKARLAAENWDRPLVVTTAVQFFESLFSNRPGKCRKLHNIAGSVIILDEAQTLPQPLLRPCLKLIDALARDFGCTLVLCTATQPAVSSSKLFADGLDGVRELAPDPVGLYRELKRVRVEMLPGRPDMATLVDAMRTEPQCLTIVNSRRHAADLYTALKTATDDEPRLLTTALCADHRRAVLADIREDLANRRPVRVVATSLVEAGVDISFPLVMRALAGLDSVAQAAGRCNRHGELGTEGGRVLLFDPTEEEGHGPPADLKVFAQTAAQVLSRTDDPLGLDAIRAYFQELYWKKGLSGALDRHNILKMLHDRADTLLFPYETVSRLFRLIDDTQAPVIVPYKPAAAKIAGLVRDLSFVSSPSAIARQLQPYLVQVPIRARKRLLETKAAEPVRPDLYGDQFVLLTNNDLYDAKAGLRWDDPTYRDIGSGFM
>CP025612.1|AUN32692.1|1106369_1106621_-|hypothetical-protein
MKVLNTVLGLLPLSLGTNTDEVERAVTVDAPATLWWMAIPNAIVFGVTFATLVTAAGTPCALMLSTRLQEWRATRMGARLDLR
>CP025612.1|AUN32693.1|1106822_1107644_+|IS5/IS1182-family-transposase
MWTDTTRALHARNGLALPSDLTDAEWSLLEPLLPAASAVGRPRKWPLRRIMEAILYLLRGGLPWRMLPPCFPPVSTVRRWFYLWRDNGLWLTVNHVLLMAMREQQGRDASPTAGVIDSQSVKTTESGGPRGYDAGKKIKGRKRHILTDTQGNLVHAPIHTADIQDRDGVPLVLAEIVKPFPWLRHVFADGGYAGDKLKVALHRIGKWTINIIKRSDKAQDFEVLPRRWVVERTLAWLNRNRRLAKDFEQTIASATKWCFIASVQLFIRRIARL
>CP025612.1|AUN32694.1|1108040_1109237_+|hypothetical-protein
MILDLSGLLHVDDPVFRRMLRQWLVGDEKPTADRTNVILFDTGKDKLVLSIPDSLLTERRQALGRVAEALASHHRGELRTAWFDLSRRADDFADAVRDLVEQMGSEQYPDAPPAADALDKFMEMERTLHAVDLSSLLREQIIFRLDDEQGLVPVMVERTVSIEALDRLFTTHMRREPWLFDQATALLDRRMLYDLLRDDAVHALPIAIKLHAATVAGEEFREMTARFPARLHGKLVVEMPFLEWVADRELYRKALNQAQADEVAVAVDHIPALAPSDTELPVVDWYRIPWLGDDGAPVDLSGGIAWLGPMARTRCILTRCRDDQALEDARTLGFRYVEGAAATRAYHDGLKVGDDQRRERTAPGNGPKDKAGVEPTEEPVKPSSWWSRLFGGGGRSGS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP025612_2	2.15\|1096790\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096790-1096823	34	CP025612.1	37650-37683	0	1.0

1. spacer 2.15|1096790|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to position: 37650-37683, mismatch: 0, identity: 1.0

gatagcctcttgcagttgatcggcgcgcaacgat	CRISPR spacer
gatagcctcttgcagttgatcggcgcgcaacgat	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1079505-1079538	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	985272-985305	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	984369-984402	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	985264-985297	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	984620-984653	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	985255-985288	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1079604-1079637	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1079599-1079632	6	0.824
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1079583-1079616	6	0.824
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	255868-255897	7	0.767
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	400895-400924	7	0.767
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	MH045568	Microbacterium phage Kieran, complete genome	23833-23862	7	0.767
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	MT110073	Stenotrophomonas phage vB_SmaS_DLP_3, complete genome	47047-47076	7	0.767
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	NC_042099	Microbacterium phage Dismas, complete genome	23824-23853	7	0.767
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1412175-1412204	7	0.767
CP025612_2	2.9\|1096391\|35\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096391-1096425	35	DQ115821	Cyanobacteria phage AS-1 contig_14 genomic sequence	846-880	7	0.8
CP025612_2	2.15\|1096790\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096790-1096823	34	NZ_CP013553	Rhizobium phaseoli strain N931 plasmid pRphaN931a, complete sequence	301225-301258	7	0.794
CP025612_2	2.15\|1096790\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096790-1096823	34	NZ_CP013586	Rhizobium phaseoli strain N161 plasmid pRphaN161a, complete sequence	315604-315637	7	0.794
CP025612_2	2.15\|1096790\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096790-1096823	34	NZ_CP013559	Rhizobium phaseoli strain N841 plasmid pRphaN841b, complete sequence	312273-312306	7	0.794
CP025612_2	2.15\|1096790\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096790-1096823	34	NZ_CP013564	Rhizobium phaseoli strain N831 plasmid pRphaN831a, complete sequence	301225-301258	7	0.794
CP025612_1	1.1\|41671\|30\|CP025612\|PILER-CR	41671-41700	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	91185-91214	8	0.733
CP025612_2	2.2\|1095930\|35\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1095930-1095964	35	AP014720	Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8	162474-162508	8	0.771
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_KT033469	Aeromonas salmonicida subsp. salmonicida strain 01-B522 plasmid pAsa4b, complete sequence	152805-152838	8	0.765
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_KT033470	Aeromonas salmonicida subsp. salmonicida strain JF2267 plasmid pAsa4c, complete sequence	135108-135141	8	0.765
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NC_009349	Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, complete sequence	73060-73093	8	0.765
CP025612_2	2.24\|1097379\|33\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097379-1097411	33	NZ_CP032344	Azospirillum brasilense strain MTCC4038 plasmid p5, complete sequence	30400-30432	8	0.758
CP025612_2	2.24\|1097379\|33\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097379-1097411	33	NZ_CP033317	Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence	102660-102692	8	0.758
CP025612_2	2.24\|1097379\|33\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097379-1097411	33	NZ_CP033323	Azospirillum brasilense strain Cd plasmid p5, complete sequence	228896-228928	8	0.758
CP025612_2	2.24\|1097379\|33\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097379-1097411	33	NZ_CP012919	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence	4353-4385	8	0.758
CP025612_2	2.24\|1097379\|33\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097379-1097411	33	NZ_CP012919	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence	153042-153074	8	0.758
CP025612_2	2.24\|1097379\|33\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097379-1097411	33	NZ_CP018222	Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL1, complete sequence	84442-84474	8	0.758
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	518523-518556	9	0.735
CP025612_2	2.21\|1097182\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097182-1097215	34	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	756415-756448	9	0.735
CP025612_2	2.21\|1097182\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1097182-1097215	34	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1056708-1056741	9	0.735
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	CP007643	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence	25701-25734	10	0.706
CP025612_2	2.4\|1096061\|34\|CP025612\|CRISPRCasFinder,CRT,PILER-CR	1096061-1096094	34	NZ_CP042515	Serratia marcescens strain E28 plasmid pE28_003	17940-17973	11	0.676

1. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

2. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

3. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

4. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

5. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

6. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

7. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

8. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

9. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

--tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tcttcaat--gcatcccgcgccgtctgctccggtct	Protospacer
  * ***.  *************.********.***

10. spacer 1.1|41671|30|CP025612|PILER-CR matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 7, identity: 0.767

aactgaatttccgcctcggcggcgccctgt	CRISPR spacer
cgcgcaatttccgcctcggcgccggcctga	Protospacer
 .*  **************** ** ****

11. spacer 1.1|41671|30|CP025612|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.767

aactgaatttccgcctcggcggcgccctgt	CRISPR spacer
acctccgcctcggcctcggcggcgccctgt	Protospacer
* **  ...** ******************

12. spacer 1.1|41671|30|CP025612|PILER-CR matches to MH045568 (Microbacterium phage Kieran, complete genome) position: , mismatch: 7, identity: 0.767

aactgaatttccgcctcggcggcgccctgt	CRISPR spacer
gcctgaacttccgcctcggcggcaaccact	Protospacer
. *****.***************. **  *

13. spacer 1.1|41671|30|CP025612|PILER-CR matches to MT110073 (Stenotrophomonas phage vB_SmaS_DLP_3, complete genome) position: , mismatch: 7, identity: 0.767

aactga--atttccgcctcggcggcgccctgt	CRISPR spacer
--tcgattacttccgcctcggcggcgtcctga	Protospacer
  ..**  *.****************.****

14. spacer 1.1|41671|30|CP025612|PILER-CR matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 7, identity: 0.767

aactgaatttccgcctcggcggcgccctgt	CRISPR spacer
gcctgaacttccgcctcggcggcaaccact	Protospacer
. *****.***************. **  *

15. spacer 1.1|41671|30|CP025612|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.767

aactgaatttccgcctcggcggcgccctgt	CRISPR spacer
acctccgcctcggcctcggcggcgccctgt	Protospacer
* **  ...** ******************

16. spacer 2.9|1096391|35|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to DQ115821 (Cyanobacteria phage AS-1 contig_14 genomic sequence) position: , mismatch: 7, identity: 0.8

tcgttcttgacgttgtccagcggca-ttgacgccac	CRISPR spacer
tcgatcttgaccttgtccagcggcagttcgcgcag-	Protospacer
*** ******* ************* ** .*** .

17. spacer 2.15|1096790|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013553 (Rhizobium phaseoli strain N931 plasmid pRphaN931a, complete sequence) position: , mismatch: 7, identity: 0.794

gatagcctcttgcagttgatcggc--gcgcaacgat	CRISPR spacer
gatcgcctcatgcagttgatcggctttcgggacg--	Protospacer
*** ***** **************   ** .***

18. spacer 2.15|1096790|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013586 (Rhizobium phaseoli strain N161 plasmid pRphaN161a, complete sequence) position: , mismatch: 7, identity: 0.794

gatagcctcttgcagttgatcggc--gcgcaacgat	CRISPR spacer
gatcgcctcatgcagttgatcggctttcgggacg--	Protospacer
*** ***** **************   ** .***

19. spacer 2.15|1096790|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013559 (Rhizobium phaseoli strain N841 plasmid pRphaN841b, complete sequence) position: , mismatch: 7, identity: 0.794

gatagcctcttgcagttgatcggc--gcgcaacgat	CRISPR spacer
gatcgcctcatgcagttgatcggctttcgggacg--	Protospacer
*** ***** **************   ** .***

20. spacer 2.15|1096790|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013564 (Rhizobium phaseoli strain N831 plasmid pRphaN831a, complete sequence) position: , mismatch: 7, identity: 0.794

gatagcctcttgcagttgatcggc--gcgcaacgat	CRISPR spacer
gatcgcctcatgcagttgatcggctttcgggacg--	Protospacer
*** ***** **************   ** .***

21. spacer 1.1|41671|30|CP025612|PILER-CR matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.733

aactgaatttccgcctcggcggcgccctgt	CRISPR spacer
gcgagcatttccgcctcgccggcaccctgc	Protospacer
.   * ************ ****.*****.

22. spacer 2.2|1095930|35|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to AP014720 (Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8) position: , mismatch: 8, identity: 0.771

ctgccgtgacgctggcgcaggccaaggcagaaatc	CRISPR spacer
tgggcaagccgctcgcggaggccaaggcagaaatc	Protospacer
. * *. * **** *** *****************

23. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT033469 (Aeromonas salmonicida subsp. salmonicida strain 01-B522 plasmid pAsa4b, complete sequence) position: , mismatch: 8, identity: 0.765

tgca-accagcatcccgcgccgcctgctccgatct	CRISPR spacer
-gcactccagcatcccgcgccgcctccaccatcat	Protospacer
 ***  ******************* * **. . *

24. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT033470 (Aeromonas salmonicida subsp. salmonicida strain JF2267 plasmid pAsa4c, complete sequence) position: , mismatch: 8, identity: 0.765

tgca-accagcatcccgcgccgcctgctccgatct	CRISPR spacer
-gcactccagcatcccgcgccgcctccaccatcat	Protospacer
 ***  ******************* * **. . *

25. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NC_009349 (Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, complete sequence) position: , mismatch: 8, identity: 0.765

tgca-accagcatcccgcgccgcctgctccgatct	CRISPR spacer
-gcactccagcatcccgcgccgcctccaccatcat	Protospacer
 ***  ******************* * **. . *

26. spacer 2.24|1097379|33|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032344 (Azospirillum brasilense strain MTCC4038 plasmid p5, complete sequence) position: , mismatch: 8, identity: 0.758

cgtgtccagactgcgcagcccctcgatcacgct	CRISPR spacer
cacgtccaggccgcgcagcccctcgatcagcag	Protospacer
*..******.*.*****************

27. spacer 2.24|1097379|33|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033317 (Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence) position: , mismatch: 8, identity: 0.758

cgtgtccagactgcgcagcccctcgatcacgct	CRISPR spacer
cacgtccaggccgcgcagcccctcgatcagcag	Protospacer
*..******.*.*****************

28. spacer 2.24|1097379|33|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033323 (Azospirillum brasilense strain Cd plasmid p5, complete sequence) position: , mismatch: 8, identity: 0.758

cgtgtccagactgcgcagcccctcgatcacgct	CRISPR spacer
cacgtccaggccgcgcagcccctcgatcagcag	Protospacer
*..******.*.*****************

29. spacer 2.24|1097379|33|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012919 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence) position: , mismatch: 8, identity: 0.758

cgtgtccagactgcgcagcccctcgatcacgct	CRISPR spacer
cacgtccaggccgcgcagcccctcgatcagcag	Protospacer
*..******.*.*****************

30. spacer 2.24|1097379|33|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012919 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence) position: , mismatch: 8, identity: 0.758

cgtgtccagactgcgcagcccctcgatcacgct	CRISPR spacer
cacgtccaggccgcgcagcccctcgatcagcag	Protospacer
*..******.*.*****************

31. spacer 2.24|1097379|33|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018222 (Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL1, complete sequence) position: , mismatch: 8, identity: 0.758

cgtgtccagactgcgcagcccctcgatcacgct	CRISPR spacer
gtaggccagattgcgcggcccctcgatcacacc	Protospacer
   * *****.*****.*************.*.

32. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.735

tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
cggcgccaacatcccgcgccgcctcctccaaccg	Protospacer
.*  .***.*************** ****.*.*

33. spacer 2.21|1097182|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 9, identity: 0.735

tgtagttcggcggcacgcggccagcgtccaccgt	CRISPR spacer
agtgcggcagcgggacgcggccggcgtccaccga	Protospacer
 **.   *.**** ********.**********

34. spacer 2.21|1097182|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 9, identity: 0.735

tgtagttcggcggcacgcggccagcgtccaccgt	CRISPR spacer
agtgcggcagcgggacgcggccggcgtccaccga	Protospacer
 **.   *.**** ********.**********

35. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to CP007643 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
tgcaaccagcatcccgcgttgcctcgcctattgg	Protospacer
******************..****  .*.. *

36. spacer 2.4|1096061|34|CP025612|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042515 (Serratia marcescens strain E28 plasmid pE28_003) position: , mismatch: 11, identity: 0.676

tgcaaccagcatcccgcgccgcctgctccgatct	CRISPR spacer
cgcaaccggcatccagcgccgcctggccgcgctc	Protospacer
.******.****** ********** .*  ....

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

44891 : 59268

Rhodobacter_phage(18.18%)

capsid,portal,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN31943.1\|44891_45722_-	hypothetical protein	A0A2K9V5D2	Lactobacillus_phage	6.6e-24	35.8
AUN31944.1\|46050_46527_-	hypothetical protein	NA	NA	NA	NA
AUN32813.1\|46776_47076_+	addiction module toxin RelE	F5A3A2	Riemerella_phage	7.4e-10	37.6
AUN32814.1\|47115_47493_+	XRE family transcriptional regulator	A0A0P0ZCT8	Stx2-converting_phage	4.1e-13	33.9
AUN31945.1\|47570_47852_-	hypothetical protein	NA	NA	NA	NA
AUN31946.1\|47953_48376_-	hypothetical protein	NA	NA	NA	NA
AUN31947.1\|48507_49995_-	hypothetical protein	B0VK40	Azospirillum_phage	2.0e-135	53.0
AUN31948.1\|50056_50266_-	hypothetical protein	NA	NA	NA	NA
AUN31949.1\|50276_50699_-	hypothetical protein	NA	NA	NA	NA
AUN31950.1\|50695_51022_-	hypothetical protein	NA	NA	NA	NA
AUN31951.1\|51069_51696_-	hypothetical protein	NA	NA	NA	NA
AUN31952.1\|51695_52139_-	hypothetical protein	NA	NA	NA	NA
AUN31953.1\|52142_52604_-	hypothetical protein	I3UM00	Rhodobacter_phage	1.2e-14	41.1
AUN31954.1\|52654_54001_-\|capsid	phage major capsid protein	A4JX01	Burkholderia_virus	2.2e-56	34.2
AUN31955.1\|54068_54962_-	peptidase S49	I3ULZ8	Rhodobacter_phage	1.0e-46	41.5
AUN31956.1\|54971_56267_-\|portal	phage portal protein	A0A142K630	Streptomyces_phage	4.8e-61	37.2
AUN31957.1\|56242_56449_-	hypothetical protein	NA	NA	NA	NA
AUN32815.1\|56448_58149_-\|terminase	terminase	A0A0R6PKH7	Moraxella_phage	1.5e-155	48.9
AUN31958.1\|58220_58739_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	3.8e-09	29.6
AUN31959.1\|58851_59268_-	hypothetical protein	A0A1S5SFB3	Streptococcus_phage	1.6e-05	37.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP025615

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 17619

Leptospira_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33880.1\|4558_4948_-	hypothetical protein	NA	NA	NA	NA
AUN33881.1\|4948_5383_-	hypothetical protein	NA	NA	NA	NA
AUN33882.1\|5724_5937_-	hypothetical protein	NA	NA	NA	NA
AUN33883.1\|5937_6630_+	hypothetical protein	NA	NA	NA	NA
AUN33884.1\|6864_7047_-	hypothetical protein	NA	NA	NA	NA
AUN33885.1\|7089_8565_+	hypothetical protein	NA	NA	NA	NA
AUN33886.1\|8551_9760_+	hypothetical protein	NA	NA	NA	NA
AUN33887.1\|9752_10889_+	hypothetical protein	NA	NA	NA	NA
AUN33888.1\|11046_11241_+	hypothetical protein	NA	NA	NA	NA
AUN33889.1\|11466_12825_-\|transposase	IS66 family transposase	NA	NA	NA	NA
AUN33890.1\|12797_13301_-	hypothetical protein	NA	NA	NA	NA
AUN33891.1\|13297_14392_-	hypothetical protein	A0A0P0ZEB3	Stx2-converting_phage	9.3e-58	40.6
AUN33972.1\|14424_15693_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	2.7e-48	36.5
AUN33892.1\|15689_16526_+	AAA family ATPase	U5N3V8	Enterobacteria_phage	4.0e-53	47.7
AUN33893.1\|16603_17173_-	hypothetical protein	S5VTD3	Leptospira_phage	6.8e-12	31.5
AUN33894.1\|17265_17619_-	IS66 family insertion sequence hypothetical protein	S5VXZ8	Leptospira_phage	5.2e-10	30.9

DBSCAN-SWA_2

47517 : 48408

Microbacterium_phage(100.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33975.1\|47517_48408_+\|tail	phage tail protein	A0A2R3ZZT3	Microbacterium_phage	2.0e-10	44.4

DBSCAN-SWA_3

67610 : 71372

Paramecium_bursaria_Chlorella_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33915.1\|67610_68303_-	macrocin O-methyltransferase	M1I5J0	Paramecium_bursaria_Chlorella_virus	1.6e-31	39.8
AUN33916.1\|68344_69151_-	hypothetical protein	NA	NA	NA	NA
AUN33917.1\|69147_70425_-	glycosyl transferase family 1	A0A125SJ91	Acidianus_tailed_spindle_virus	1.8e-07	35.2
AUN33918.1\|70421_71372_-	hypothetical protein	A0A0B5J146	Pandoravirus	2.1e-05	28.9

DBSCAN-SWA_4

78007 : 95491

Tupanvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33923.1\|78007_78922_+	hypothetical protein	M1I6G6	Paramecium_bursaria_Chlorella_virus	4.0e-06	24.3
AUN33924.1\|78925_80980_+	hypothetical protein	NA	NA	NA	NA
AUN33925.1\|81116_82091_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	1.8e-44	35.0
AUN33926.1\|82459_82876_+	hypothetical protein	NA	NA	NA	NA
AUN33927.1\|82872_83985_+	erythromycin biosynthesis sensory transduction protein eryC1	A0A2K9L470	Tupanvirus	1.7e-30	33.6
AUN33928.1\|84002_84524_-	D,D-heptose 1,7-bisphosphate phosphatase	NA	NA	NA	NA
AUN33929.1\|85346_85718_-	stability/partitioning determinant	NA	NA	NA	NA
AUN33930.1\|85732_86428_-	ParA family protein	A0A0A8IL09	Aurantimonas_phage	4.5e-50	49.8
AUN33931.1\|86564_87548_-	protein CapI	A0A1D7XFE8	Escherichia_phage	2.2e-26	32.1
AUN33932.1\|87697_89551_-	adenylyl-sulfate kinase	A0A1V0SGC3	Hokovirus	5.1e-32	28.8
AUN33933.1\|89550_90453_-	sulfate adenylyltransferase subunit CysD	NA	NA	NA	NA
AUN33934.1\|90619_91984_-	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
AUN33935.1\|91949_94190_-	peptidase C39	W8CYL7	Bacillus_phage	2.3e-34	27.3
AUN33936.1\|94312_95491_-	hypothetical protein	E3T539	Cafeteria_roenbergensis_virus	5.2e-14	25.7

DBSCAN-SWA_5

111490 : 119478

Leptospira_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33949.1\|111490_111844_+	IS66 family insertion sequence hypothetical protein	S5VXZ8	Leptospira_phage	2.7e-19	46.2
AUN33950.1\|113471_113657_-	hypothetical protein	NA	NA	NA	NA
AUN33978.1\|114806_115478_-	hypothetical protein	I3UL74	Ostreococcus_lucimarinus_virus	4.3e-05	24.4
AUN33951.1\|116323_116716_+	hypothetical protein	NA	NA	NA	NA
AUN33952.1\|116712_117033_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	1.1e-24	52.0
AUN33953.1\|117390_119478_+	recombinase family protein	A0A1B2LRQ3	Wolbachia_phage	2.2e-07	24.1

DBSCAN-SWA_6

124071 : 126039

Stx2-converting_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33955.1\|124071_124419_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	1.0e-34	61.3
AUN33956.1\|124461_126039_+\|transposase	transposase	A0A0P0ZEB3	Stx2-converting_phage	4.1e-107	43.4

DBSCAN-SWA_7

135023 : 140662

Paenibacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33961.1\|135023_135780_+\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	9.4e-25	43.3
AUN33962.1\|136851_137436_-	resolvase	A0A0C4UR34	Shigella_phage	1.2e-40	51.4
AUN33963.1\|137689_140662_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	2.9e-247	45.4

DBSCAN-SWA_8

146768 : 148417

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33966.1\|146768_147827_+	dehydrogenase	A0A222YW25	Synechococcus_phage	1.8e-50	37.5
AUN33967.1\|147826_148417_+	phosphoheptose isomerase	A0A067XQR2	Caulobacter_phage	6.4e-13	30.1

DBSCAN-SWA_9

153182 : 154475

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN33970.1\|153182_154475_+	histidinol phosphate phosphatase	A0A222YXG2	Synechococcus_phage	5.3e-12	31.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025611

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP025612

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP025615

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection