CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP033021	Mycoplasma hominis strain TO0613 chromosome, complete genome	3 crisprs	NA	0	1	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP033021_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033021_1

39327-39550

Orphan

Consensus_repeat	Method
CATTTGTTTTCAATTAAAGATTGGGTGGCCTTGAGGATCTAGTTGGG	PILER-CR

2 spacers

The CRISPR arrays of CP033021_1

>merge|CP033021|1|39327-39550|PILER-CR
AAAGATAGGGTGGCCTTGAGGATCTAGTTGATTATATTTAGAGATGTCAAGCCCTTGTTCTAAATCTTTGCGGATTCGTTCCATTTGTTTTCAATTAAAGATTGGGTGGCCTTTATGATTTAATTGGGTGTATTGAGATATATCAAGGCCCCCTCTTAAACCTTCACGGATTTGAGACATTTGTTTTCAATTAAAGATTGGGTGGCCGTGAGGGTCTAGTTGGG

>CP033021|1|1|39327-39550|PILER-CR
AAAGATAGGGTGGCCTTGAGGATCTAGTTGATTATATTTAGAGATGTCA	AGCCCTTGTTCTAAATCTTTGCGGATTCGTTCCATTTGTTTTCAATTAAAG
ATTGGGTGGCCTTTATGATTTAATTGGGTGTATTGAGATATATCAAGGC	CCCCTCTTAAACCTTCACGGATTTGAGACATTTGTTTTCAATTAAAG
ATTGGGTGGCCGTGAGGGTCTAGTTGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP033021.1\|AYN65143.1\|44876_47177_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367119
CP033021.1\|AYN65135.1\|35061_35424_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65142.1\|43277_43685_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65140.1\|41594_42494_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65132.1\|31054_31828_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223510
CP033021.1\|AYN65144.1\|47184_48426_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65131.1\|30220_31003_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65134.1\|33854_35060_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65137.1\|37698_38208_-\|sugar-phosphate-nucleotidyltransferase	unknown	unknown	unknown
CP033021.1\|AYN65129.1\|24201_29787_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378012
CP033021.1\|AYN65145.1\|48730_49522_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65139.1\|39929_41096_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65146.1\|49508_49709_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65133.1\|31814_33836_-\|DUF87-domain-containing-protein	unknown	unknown	gnl\|CDD\|274279
CP033021.1\|AYN65136.1\|35567_37271_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368653
CP033021.1\|AYN65130.1\|29773_30166_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
CP033021.1\|AYN65138.1\|38349_38541_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65141.1\|42504_43263_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65147.1\|49795_51946_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274529
CP033021.1\|AYN65691.1\|43857_44850_-\|DNA-(cytosine-5-)-methyltransferase	unknown	unknown	gnl\|CDD\|238192

Protein	Function_ID	Function_description	E-value
CP033021.1\|AYN65143.1\|44876_47177_-\|hypothetical-protein	gnl\|CDD\|367119	pfam02534, T4SS-DNA_transf, Type IV secretory system Conjugative DNA transfer. These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.	9.98401e-35
CP033021.1\|AYN65147.1\|49795_51946_-\|AAA-family-ATPase	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
CP033021.1\|AYN65132.1\|31054_31828_-\|hypothetical-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	1.3316e-06
CP033021.1\|AYN65129.1\|24201_29787_-\|hypothetical-protein	gnl\|CDD\|378012	pfam08496, Peptidase_S49_N, Peptidase family S49 N-terminal. This domain is found to the N-terminus of bacterial signal peptidases of the S49 family (pfam01343).	0.00334019
CP033021.1\|AYN65130.1\|29773_30166_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	1.60665e-19
CP033021.1\|AYN65136.1\|35567_37271_-\|hypothetical-protein	gnl\|CDD\|368653	pfam05887, Trypan_PARP, Procyclic acidic repetitive protein (PARP). This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.	0.000560418
CP033021.1\|AYN65691.1\|43857_44850_-\|DNA-(cytosine-5-)-methyltransferase	gnl\|CDD\|238192	cd00315, Cyt_C5_DNA_methylase, Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the mammalian genome. These effects include transcriptional repression via inhibition of transcription factor binding or the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability.	6.41902e-54
CP033021.1\|AYN65133.1\|31814_33836_-\|DUF87-domain-containing-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	9.31139e-15

>CP033021.1|AYN65138.1|38349_38541_-|hypothetical-protein
MSKYFYRLRGSQSTGKNAKTYSFGSAQQYNKALIMAQDAISKNQFKEVQIERIQVIKIIKQNS
>CP033021.1|AYN65137.1|37698_38208_-|sugar-phosphate-nucleotidyltransferase
MSIDDEWYTQEKDIKYFLENFKIDKKKTIWCPFDTQQSNFVIVLKSLGYKVIYSHIDNGQDFYKYEPNENYDLIISNPPFRNKANIIKRLQELNKPFALIFGVQCFNSGGFVSQLQKLKNLELVFLTKRIKFLKNYKQDLKNIPQPTFHSLWICSGITNKPLSILEGVK
>CP033021.1|AYN65136.1|35567_37271_-|hypothetical-protein
MKKSKRILLTIGSTIALTTLPIMAMSCEWLDKLINKNNPNPTPTPGPDSGLVNPNPKPQPTPPSPVPTPEPKAEEKEGYVTYKSTNEDYLKKNNTYYFSKLLYDPVDLSDEVYNSQDWKLYRPKMWFSLTNKPENETETESKLEKQLDKWHMSLDNVHFTNDCESACGIWNIIRKLAESDENKEGINQGGRFKPKDNESYNEALMRFLKEMDDYLDPKYAFRGLTKDKNHIAAVNQNLAKDRDWISKKLIYSADSKMPSTFIKENFIENSFDDIAKTNQDPFVKELISDYEKAMYKGWIFENKAKNWFVAPFSFGSNPTMRNKFPDQTFNMYTDKNGLDKTTPTPAYNNYNPVAFNFLVMERFDLSERLNFEVYKNLIQWLISFNNINSENKSKWSEIENDKKIQLKNASTDLVKALVKFIDWHHLLLGEFENPDDKHSTLADLFAMKSLTMGDKIDFDYTYRFAYKFLYEKLVPTMVANGWNMPNEFKNLEEDMLDRNKKDSYIYDYIFKYINVIFKAKYNDIDEIKKPNGYLDLNNKEHWQKLFLDNVLKKWNSAFNINVDLKEF
>CP033021.1|AYN65135.1|35061_35424_-|hypothetical-protein
MKIDDKSFSFLGNFSETIMRSIFIALIPVAIILLIGMILWARSQNAATKDPNERKQNNLKVWGALSALIILVVMWPLIELIKANVKKPSNVGSQASLFTHAILNNFTISIPKLTNFNLMV
>CP033021.1|AYN65134.1|33854_35060_-|hypothetical-protein
MGKFLEAIINPIINLIATPIRLMWFVPLAAIGLIGFTIFNLLFFLFKLFSLDLNNYLMFNLLPGQSYSQFSVARPWYQFLIISFVLWLINFFVFVIRYSKESNGLKAKEIFVQALKSTVGGVLTLILFQVVILFINIIFIELTKALYGDYNDFFNFGFGQISNNIIRNMMPPQAFVPDKYWDPFPYGSPIANPLWGLGFPAWWDWTKNITGYALTIGLSIAIVGVLISIPLIFVLFDIISRVFINWLLFISFPLIPAFSINDGGKRIRVWKEKYFGNLLSCSIYGVGIMMLGSFIGLANTFMTSATNYMIGAFSSLSNFTTIKAVLALLSTCFLVIGSAFAFKKLSEMAIAFVGSEVSGGQSARLAMSGARSGAGAYKTVKDAALRGTNVGAAYKVASFLK
>CP033021.1|AYN65133.1|31814_33836_-|DUF87-domain-containing-protein
MTQLQPSRIKHRSSKIWKTFKTKDLIEFVVILLLSFFISFGFSQLINVKLIFFAFWIPTFLLGIILIMPNRKNNCKVYVLIWRMFVFWTIPKRFVKNVQNNSFRSSLDLNPYSCLVNEYVVKNKNSKISFYNPRNDKENYLAVFKLNGLNIWNEDELTREAFIDSFAKTLNILTYKVSFVKLEEKVNYEENIKYIEAKQAKQINNNAMWNNYYDLNIKDFSNLNKEAISNNFYLIVNGENLNDLNEYLEVIIDKFQDTGIGLEKLHKARLLTFLNKLNMFGIDSQNIQEYCNDLDAKFGVENSLDNLFIYNQVIIRDKYLQINDNYVKINCLNKLPFELSDKWIKTLFSINGTCIWNNFPWNNNFANKKMDKSMMASIDTTNATGSVSANLVGSIDEQATMAMMYQVNKDEYKLFDSNFFFVSKATDLAELNRQHRIARNIASKKNISLNDLKYRQLLGLSEACNYPFERLEREYYQITSINLALGWPFETENHNDSNNLLLGYSEATRSPLSFRLFDMYHSNRTNFNMFINGTSGKGKTTFTMKLLTSILAANNKVVVIDPQGEYRELAQKLNGQIIDLGAGKNTIINPLQIRNSLKDATGNDTSSLINNHLSWLESFFKVLINIEDHKWILLQNVIKEFYEDRGIYKLASIEQLKAVEWPTISELIKYVQL
>CP033021.1|AYN65132.1|31054_31828_-|hypothetical-protein
MSNYKTLHLNNPEAKRAILVELCESFSFLFENNGRYQNLFNGHTNIKLDNDFVVFNTQNLINGADNIGAKLGTMCLLNFVSEIVFNNWMHNEMLKKKYLQEHNIKLMDAKQVEDTIRFCAVIVDEAHLYIDPDNPAILKYMVQMTKTVRKFNAGMIFTTQNPGDFTVNNATSDDASRIIQNCQYSVFFGLKDQDIDKVQQLFKNSNQLLQSEIRYLVNARYGKCLFSISSNKRIRVEIYYNKLEQELFFKFLNKEWI
>CP033021.1|AYN65131.1|30220_31003_-|hypothetical-protein
MKTNKNELDQDFDNLDNNEILSNDNQTQNEDDFIENINLTSDNQVNNIMNSITSSQPKKQKERKQQNNFEAQFSGRFTDPEDVGMFYRWKKELEKNGKTVYKELNNVIRSYLLANEKKEIMRDWKHDLFQALRKVSWSALSPYQLQINRRFRSMDIEMSIINLKLNMIINALFKDNGDLEKQIDNPGADILAESKFFERTIRGAVNKLTNDWTKKMANKIQNSERAWNDFLSSLSENEFDDILQEIGATNSTAQEQIEEK
>CP033021.1|AYN65130.1|29773_30166_-|single-stranded-DNA-binding-protein
MNKVILTGRLVNDNWKPFKSEKGQALPFVIALFEQANKTNFIEITCFNKLAEHVMKYVKKGDLLEVVGKLHNAKFSSKNNETIYKTEIIAKNITFLTKSKSNIQPISKETNSENNEKDIFGIDFFEDEEN
>CP033021.1|AYN65129.1|24201_29787_-|hypothetical-protein
MKKIKKTLLIAGGIFSIASASLFSLSFSRNEHYSSYKYEEIDKDQYSFLNNKNLLKSFFTNLTYRKDSRQDSFIFDPKDYSSNPLYCDQRFIANTNDRLEFLKELSINDINKINNQPFGDYKITLENNANEPSNVGNTDPEEYNKLPSQIPSWLQGYEKYVSSLTEGWISEGDIIPGELEERYPNAWNPGQIIQTIKKSNYSINWVNAQSFKKLTKDYDIKIKTFNNRLSDPKINSSDIAHSDEAYIAYDKFKLSYNDHLEVNYDFTKWHGIDLEDAYSLICFLANYNNFKHFQKFMLAFHLQNSSQEIVIDSDTMGKLTTGIDLNIFKGGKSNLEKLQEIAKQMDNETSVGNFIIKYGYEVKPISDGNHFNLIFKIKQLKYKGKDITNSFASKIFNEADTYNFANNFAKNQQSKIQIKNLYNMFYSLFKGKTIMANVPVRFTPSQIYQTYADKTGFVSRLWFKYGVVLNQNNLSNIQENHSFNFKDNLQEDKPIQLEPANGNYGGKWLVHTPLQVNFDTTLEENEVLFINGQKVDVLNRHFVYHLKDLRRSASDEEKIALEKNDSNKPQEELNDHNSRKKNEYIVEIKKFKPGTNNSGEPIATYKIKFVIVEQPINQSFKWFAWDPENNPKQKELITKEITKDGRILVDKEGNPLPNPKYDPTIDPKTGTKNQLIWIKNGTLAKEITKNLKFWYPDIKMLNDFGIFAEGAVLGKGALRNLILDKNIAKKSNVTYYKCKLYDKGSNKWLSPSEIKPEPLSSSNGNSENAYMSEEGIWIVYAATSTSISNIKLVLIDESNSPKNLFWQELENKKDNYGIDLMKKFEPFWQSTLGIYFKKWLIESKHYDKEQLDKLTYDELLPLYNECVNSSWKFADNDNSSIENAINIFNDFKWSKLQNFNGLTDKQAIKDKVLEYIRTNMSSNALTKNLIENKDWFISEFSNITEENKFLEELANVSIYGTEQNQNYEGVKLTLIGKGLYANSRKEIYFRNEAWHVYNPPIDLSTLDIQNEFILNVSKKSFEEKNIPEDVIDERYRKAIEKEVINFITNQLLQYQLKTKSSGKEIEMLLNKDVEIANLNEVIAHLMRGKALSSFVGLKLVSKNANLHNYKIINFKNLGEGGKFNLRNLSYILMDNKNVIQETKPSQIRKKVIEIVVNAASKLGLEINNDYQIFAINNDAYWLELVSKYDDPKLKQNKEFYEKLQQALKALQLRKTFKYEGKDKEIEFEPKDLDLKNQLEQYKNSIIEELEREIYNNSLNLEVLYKKILLLPTNKTTGFGYGYIINKANKEYNPAIDPEWKPNPNPDDEDKAVNIFNDFKWSKLQNFNGLTDKQAIKDKVLEYIRTNMSSNTLTKNLIENKDWFISEFSNITEENKFLEELANVSIYGTEQNQNYEGVKLTLIGKGLYANSRKEIYFRNEAWHVYNPPIDLSTLDIQNEFILNVSKKSFEEKNIPEDVIDERYRKAIEKEVINFITNQLLQYQLKTKSSGKEIEMLLNKDVEIANLNEVIAHLMRGKALSSFVGLKLVSKNANLHNYKIINFKNLGEGGKFNLRNLSYILMDNKNVIQETKPSQIRKKVIEIVVNAASKLGLEINNDYQIFAINNDAYWLELVSKYDDPKLKQNKEFYEKLQQALKALQLRKTFKYEGKDKEIEFEPKDLDLKNQLEQYKNSIIEELEREIYNNSLNLEVLYKKILLLPTNKTTGFGYGYIINKANKEYNPAIDPEWKPNPNPDDEDIVSPEDIPKDPNRIKKVVKTWWFPLVVIIGILTFLVASIFIIKSLLRKYGWSFGKRAKRIRRQNPNKQSYQEKHSNKRQEKLAKKEAKNLKRQTRKQEKASLKKAKKDKKTKNNPKINNEQNSIN
>CP033021.1|AYN65139.1|39929_41096_-|hypothetical-protein
MISNKKLLENFFFPLEPNPNDKMETFVIKSDGIEYNYQFPGFINFWLYGQNISTIFMDLSVEWPNINYEVNQENIIFKFKANQQANIKGFSNTEEFCIAQNSNVEISVPCYKPFSVVILEQIDSLHEKISIFNYLNQNNFNLAQIKAIYKNYHYYYKHILFRDKTFEYLDNGIKSVDLDIIAKDFEKKINNLATYNSTLNEWNDVDWEKIKLYWSPDYKNNVQNHFANKLFELQQGNSKLNFEKYFCKFKKIDDSYCVKKFYDADQMHLIRTSLNQEFNVLKYVNTSYDYHQIEQIWLGLNSGLDVSIYAKQNSFNRPIFNWKQMEQIRIGLEHGLNVSKHTHLAPKSSLSDFDKTPTDLQDSKVINEYNKSSHTPSDTQSKSHSLTK
>CP033021.1|AYN65140.1|41594_42494_-|hypothetical-protein
MINQNQELEKFLFPLETIGWAKPKIFLIKINDNKYKYKFKGFDDFRIYSQNLSKIFFDAGVNWSNVDYKINKQNTIFSFKNNNDFEIRGYSNKNSIEVPQNSKIEISVPIKKVYTKEYILDSLNVQNTKFQIYEYLKQNNFNLNQIETIYSNYHDYYKHILFRDKTFEYLNNKINVNDLREIAKDFEKKLDIMALRKAIEFNKLNPSKISEDEINYRKYWIKQSSDYKNIVQDHFANQFLNQCLDLSKYTHLTSKSSLSDFDKTPTDLQDSKVINEYNKSRSQSNQNKTLESKNINRCI
>CP033021.1|AYN65141.1|42504_43263_-|hypothetical-protein
MEIKPFKMNDISYMTQYDDIWYSDRKVLNYFNNTLFSLNSEEEQKLYKEQICQISKQMEKSDDFVNKWIYDKLITSETRPNYLEGCSNIINTLSSDNWINESDWLKYPASQFMEENDIIRKDNLEEIIDVDLKTNGYESQWINGTTKFNVLNNLSNEEYVYVNPYLEIEPINIKEIKDDYIEALKTFDLDDLLESRDEKSLINLDSNESSKSSLSDFDKTPTDLKDSKVINEYNKSSHTPSDTQSKSHSLTK
>CP033021.1|AYN65142.1|43277_43685_-|hypothetical-protein
MTFEELHKDLDYWKEHEPQDVWDYYLAYDLADQEFKTKGIEAEGWAFDIEDIISINRIYDVEYIAINEYGRAMVISVEDAGRFFQNQEIEENESSKSSLSDFDKTPTDLQDSKVINEYNKSSHTPSDTQSKSKTL
>CP033021.1|AYN65691.1|43857_44850_-|DNA-(cytosine-5-)-methyltransferase
MKVVELFGGIGAIRKALIRTIKPPNFEIIDYVESDKKTVNAYNAIYNDFYKPLDIRDYSLPNNINVDLLFHGSPCQDFSCAGKNIGGSKESKSRSSLLWETIRIIKEAQIKPKIVIWENVKNVLSKKHKPIFDAYIKALNDLGYVSHYKIINSLDCGIPQSRNRVFTVSINKNYLKQFNNLDTFNCLNNKYKNINDFLQPNVINPKYFIRTNCPSMINAITNHKIKIIENKVFTITTKQMRWNNQGVVKVEISKVPNNSNLAKMIIDNKPYYLRVITPLEAMLLMGYDQQDYERIKNFCDSQIYKFAGNSIVVNVLQEIIKHIFKLTKEE
>CP033021.1|AYN65143.1|44876_47177_-|hypothetical-protein
MEEQEKLSKSKIIGKTLLSIIVSTFLFFVLTFIINVFMGQNKNPGHFKLFWNSTVTLLKTKPDIFVYIGLGISILVFCFIFWRQIKSLGKKISKYLFGAKASQNWLWNYQLGEGSKTKYNKLFRKMINAETEPNWLFTFDKTQKYWYVNDKDDNSIVNGPPGSGKTHRIILPNIEFMAQLDYSKKPNLIISDPKKEIIKFTGGLLTENDYKIYVIDFSDPKLSLKWNPLSYAWDLAVDGEKFKNLTFEERINKSLEVINNVIESLNWGKAVNGNMWISQAKKTLIVITNFLLLLGIDDKNIIHKNNFNFETIASLLNTSHWENDKNISAWILYAKKRALDDNNYYWKKVYNNIEDLSKTPKETFGGILAEAQSVLNVFNNDENLKMVLRDTESFNLVDIVSDPKPFAIFIHYPDHKPTSHFLVSMLVEQIYQSLIEQANKNDNLKLDRKAFFLLDEFGNLPVVVNFDNKLTICRSRNIFFMLVVQDYNQIKKYNIYGEGTAQVIKNSCQVVYFLASNDEQTLNDISKALGTKEVKSKSYTTSDNHSSSTESEKSKPVMEVAELKSKKPDDLIIIKNGYKPLLIKTLLAYKYFPNDNYVYTRNESKLLTNADFELFDIRSLEKLIKFDNSKQKKQNNKNQKVSEHNDLTNLEDVEDPEDLSQEQKIQRMKIVFGKLDLWNNYINLKNDYKRTLIPYKKNQIKEQIEETLSLMWEQYVANDLENDLVNILWSEAKKRKIPNYYDLKVDILLQLLHPLEDVSKLIEKSN
>CP033021.1|AYN65144.1|47184_48426_-|hypothetical-protein
MDKVWTEFNFITPNTMYKTKLGNTHDFKSWVNSGLVVDYITRPDKCVVFKEDENNYDAMKLLLTKEDKINWYRQHLKINQNSNQSGLYNLLDNDPKDVNLENVKNDLKNLKGNYWELIVNPGDLGLDNNVLCKDKWHEVLKPNFERFLKANSFDLENVNVFYSIHGNTDYPHVHMFWYEKEHKHKKAKLNLNSINVFGYKVGLSIKYDEDYQKINALTKDIWNTRKQIVGIIANNFANSNEVISKSNLCQEFIKSSKSILDEVLNKKNISYSRISDENKKNIETIKKFLLNYDNDYSKLFNSYQKQINDLNNLNIEDKFLKQRISKIINNEMDDFQKQVGNKIIKTLLNAYKQNNNAFTSRKNFASFFNEFLKIFSLNRSEWALRNLAEREFLAKDLKELELVEEFYRSKLVH
>CP033021.1|AYN65145.1|48730_49522_-|hypothetical-protein
MGAYSEFMVMQQEAKLNNDYSLVDAYKRNLNWRRNYSKKIYDKLSDIAISKILKSKIVISESYYQKLKTNKVLLEVFMVIKSFKNKKIKIIDLINLGFKKTSIKSAIKRLIEIKVLDGEFYKKYKLLKLKKIVLKNPKENYWILNGYDALKIFLLNGLSNAILYVINSHKSKQLNAKKLHCKINSKKVILQNAYYAKFNWSNSKIYLMNKAIANYFGVEYLQMFAILRSQEKKFITIKNEFGYSKIKFNGYKFSTQRYLLMQI
>CP033021.1|AYN65146.1|49508_49709_-|hypothetical-protein
MGLIPNKEKKQDHKGLAFFSIIHKKISLKKRRANSELFQQLHKLYHVLFVFFKKLKNFWKEFYGCL
>CP033021.1|AYN65147.1|49795_51946_-|AAA-family-ATPase
MEASYTPYEQEKDPLKEFGRNLTELATQNKLEPVINRDEEIRSLVRILSRKTKNNPVLVGEPGVGKTAIVEGLARKIVENQVPENLKGKQLIEIDLPALVAGTQYRGQFEERLKKVLKKIDEANGEIILFIDEIHMIIGAGGTGDSNMDAANILKPMMARGQLHLIGATTLDEYRKYIEKDPALERRMQKILISEPSIEDTITILRGIKERFEAYHEVKIDDSAIVSAANLSARYIADRFLPDKAIDLIDEAASNIKTEMNYLPEPLEKINYQIARLEIEKAALTNDSETKQTAIKNKERILEIDKELNTLKLQKVDLEKRWKQEKEDIQKFSSIKENIEELNRKLPLLQSEGKYVEASKIMYVLVPELIKTRDELEQKIQSRKNRLIKEVVDAEEVADIVSKWTNIPVNRLLENQKQKILNLSETLKKRVKGQDQAIELISDAIKRSKANINDPNRPIGSFLFLGPTGVGKTELAKSLAEALFDDENHIVRLDMSEYMEKHSVSKLIGSPPGYIGYDNGGQLTEKIRQNPYSIVLFDEIEKANSDVLNILLQILDNGTLTDSTGRVVNFKNTIIIMTSNIGSSEIINKSLTIDGVRALLLRSFRPEFINRIDEIVPFNPLSPAVVCDIVKLELSKLKKRVINNHNLVINFDDKIVKFVADNAYDSAFGARPIKRYIQKNIENKLAMEIIKGNLVEGDVALLTVSNNNVIELQTNN

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Crispr_ID: CP033021_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033021_2

142910-143017

Orphan

Consensus_repeat	Method
CCAAGCTGAATACGTGGGTCCGATTCCCATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033021_2

>merge|CP033021|2|142910-143017|CRISPRCasFinder
CCAAGCTGAATACGTGGGTCCGATTCCCATCACTTGCACCATTGCGGATGTAGTTCAATGGTAGAACATCAGGTTGCCAATCTGAATACGTGGGTCCGATTCCCATCA

>CP033021|2|1|142910-143017|CRISPRCasFinder
CCAAGCTGAATACGTGGGTCCGATTCCCATCA	CTTGCACCATTGCGGATGTAGTTCAATGGTAGAACATCAGGTTG
CCAATCTGAATACGTGGGTCCGATTCCCATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP033021.1\|AYN65208.1\|136433_137285_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65695.1\|137271_137724_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379241
CP033021.1\|AYN65219.1\|152386_152890_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65217.1\|149265_151860_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237258
CP033021.1\|AYN65206.1\|134536_135382_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65212.1\|144165_144609_+\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
CP033021.1\|AYN65207.1\|135480_136131_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65209.1\|138819_139671_-\|ribonuclease-III-family-protein	unknown	unknown	gnl\|CDD\|223644
CP033021.1\|AYN65203.1\|128924_131066_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367390
CP033021.1\|AYN65213.1\|144608_145301_+\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
CP033021.1\|AYN65696.1\|140960_142667_+\|excinuclease-ABC-subunit-C	unknown	unknown	gnl\|CDD\|234792
CP033021.1\|AYN65210.1\|140044_140971_+\|gamma-glutamylcyclotransferase	unknown	unknown	gnl\|CDD\|119400
CP033021.1\|AYN65214.1\|145410_146784_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
CP033021.1\|AYN65205.1\|133898_134498_+\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
CP033021.1\|AYN65216.1\|147743_149174_+\|trigger-factor	unknown	unknown	gnl\|CDD\|272913
CP033021.1\|AYN65211.1\|143469_144063_+\|FMN-dependent-NADH-azoreductase	unknown	unknown	gnl\|CDD\|234946
CP033021.1\|AYN65204.1\|131325_133488_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367390
CP033021.1\|AYN65215.1\|146987_147701_+\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65218.1\|151868_152300_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239520
CP033021.1\|AYN65220.1\|152973_154977_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235943

Protein	Function_ID	Function_description	E-value
CP033021.1\|AYN65214.1\|145410_146784_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP033021.1\|AYN65695.1\|137271_137724_-\|hypothetical-protein	gnl\|CDD\|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	8.82785e-05
CP033021.1\|AYN65217.1\|149265_151860_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237258	PRK12903, secA, preprotein translocase subunit SecA; Reviewed.	0
CP033021.1\|AYN65213.1\|144608_145301_+\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	3.50232e-108
CP033021.1\|AYN65209.1\|138819_139671_-\|ribonuclease-III-family-protein	gnl\|CDD\|223644	COG0571, Rnc, dsRNA-specific ribonuclease [Transcription].	1.97166e-39
CP033021.1\|AYN65203.1\|128924_131066_-\|hypothetical-protein	gnl\|CDD\|367390	pfam03202, Lipoprotein_10, Putative mycoplasma lipoprotein, C-terminal region.	4.23309e-37
CP033021.1\|AYN65212.1\|144165_144609_+\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	9.13571e-71
CP033021.1\|AYN65696.1\|140960_142667_+\|excinuclease-ABC-subunit-C	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	7.57144e-99
CP033021.1\|AYN65210.1\|140044_140971_+\|gamma-glutamylcyclotransferase	gnl\|CDD\|119400	cd06661, GGCT_like, GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is encoded by the gene C7orf24, and the enzyme participates in the gamma-glutamyl cycle. Hereditary defects in the gamma-glutamyl cycle have been described for some of the genes involved, but not for C7orf24. The synthesis and metabolism of glutathione (L-gamma-glutamyl-L-cysteinylglycine) ties the gamma-glutamyl cycle to numerous cellular processes; glutathione acts as a ubiquitous reducing agent in reductive mechanisms involved in protein and DNA synthesis, transport processes, enzyme activity, and metabolism. AIG2 (avrRpt2-induced gene) is an Arabidopsis protein that exhibits RPS2- and avrRpt2-dependent induction early after infection with Pseudomonas syringae pv maculicola strain ES4326 carrying avrRpt2. avrRpt2 is an avirulence gene that can convert virulent strains of P. syringae to avirulence on Arabidopsis thaliana, soybean, and bean. The family also includes bacterial tellurite-resistance proteins (trgB); tellurium (Te) compounds are used in industrial processes and had been used as antimicrobial agents in the past. Some members have been described proteins involved in cation transport (chaC).	6.88009e-09
CP033021.1\|AYN65205.1\|133898_134498_+\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	2.04316e-96
CP033021.1\|AYN65216.1\|147743_149174_+\|trigger-factor	gnl\|CDD\|272913	TIGR00115, tig, trigger factor. Trigger factor is a ribosome-associated molecular chaperone and is the first chaperone to interact with nascent polypeptide. Trigger factor can bind at the same time as the signal recognition particle (SRP), but is excluded by the SRP receptor (FtsY). The central domain of trigger factor has peptidyl-prolyl cis/trans isomerase activity. This protein is found in a single copy in virtually every bacterial genome. [Protein fate, Protein folding and stabilization].	4.16998e-87
CP033021.1\|AYN65211.1\|143469_144063_+\|FMN-dependent-NADH-azoreductase	gnl\|CDD\|234946	PRK01355, PRK01355, azoreductase; Reviewed.	1.97587e-113
CP033021.1\|AYN65204.1\|131325_133488_-\|hypothetical-protein	gnl\|CDD\|367390	pfam03202, Lipoprotein_10, Putative mycoplasma lipoprotein, C-terminal region.	1.51329e-33
CP033021.1\|AYN65218.1\|151868_152300_-\|NUDIX-domain-containing-protein	gnl\|CDD\|239520	cd03428, Ap4A_hydrolase_human_like, Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant enzymes fall into one subfamily and fungi/animals/archaea enzymes, represented by this subfamily, fall into another. Bacterial enzymes are found in both subfamilies. Ap4A is a potential by-product of aminoacyl tRNA synthesis, and accumulation of Ap4A has been implicated in a range of biological events, such as DNA replication, cellular differentiation, heat shock, metabolic stress, and apoptosis. Ap4A hydrolase cleaves Ap4A asymmetrically into ATP and AMP. It is important in the invasive properties of bacteria and thus presents a potential target for inhibition of such invasive bacteria. Besides the signature nudix motif (G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val) that functions as a metal binding and catalytic site, and a required divalent cation, Ap4A hydrolase is structurally similar to the other members of the nudix superfamily with some degree of variation. Several regions in the sequences are poorly defined and substrate and metal binding sites are only predicted based on kinetic studies.	5.2794e-30
CP033021.1\|AYN65220.1\|152973_154977_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235943	PRK07133, PRK07133, DNA polymerase III subunits gamma and tau; Validated.	0

>CP033021.1|AYN65696.1|140960_142667_+|excinuclease-ABC-subunit-C
MINKEIIIKNVPHKPGVYLWKNKNSNIIYVGKAKDLKNRMLQYFDIKMQNSFKTEKMRQEIADFSTIILSSEREAFIEERKLIDFYKPFYNVLFPTRDSFPYIRVKLLSTNKLIIDIKNHYKKEPNSIYYGPIPDNKNFKPLIRYLNHLLLSKDGIIIEKQSPEFAKQRFEQAKSIMKFGPDFKRNLKQKINEAIEMNLFEQARFYDQILDLLNYNKQSQNIFIKTIKDIDVFGFYQYQNYMLVNVMIYKNGSLVNSYDYIFEIILNEHEFVNQFIDEFYVNNQLPAQIIIPLKYYELGGFDYNDKVSAPLNKLNKNLIDIAIENASNNIEQKIKNYLSKQTKDNEIFNKLCSYLNVYAERIVLFDNSFLSNTNEVIGAACYFKNGQAFKKFYRFYNLKLNLLRNADVEYMQQTSFNYLKDLGDQVDVVIVDGSIGQINEVKKSMAFLNLNIPLFGLVKNSKHETQKLIDSNNNEIKIDDQDVFNLLSRMQTEVDRFAKYRYNQKQRKSMLSNPLLKIKGIGFKTIEKLINYFGSYKKIQQASFDEISKVANKKVAKLICEDKGESFY
>CP033021.1|AYN65210.1|140044_140971_+|gamma-glutamylcyclotransferase
MSNEEKIYVFSYGTIQDPQFYKELLPNSKPMPAILNGYAKCVDETMYFLLKKDLSSQVKGSVFEISKEELFLIDRWELFPQYQRFQVNVLLTETNEILENVYVYTKLEVGKYYLATDDMGFSRNPNANENNLNAFIEMEKAIKDFPLTDYIFLYDINEQEFEEINKLTHPYAALIIDDKENRNYVAIHGSIFAIKEDGKMYAALTSFSQKSNLNSIFYYQAFNEKLLNSKPEITLKSLYDNTNIDFLINKKPVYYLSSREDKTINETQVGWYENKAFELVEKDFDIDPFIRFNKMLKAFFDTKQKNDK
>CP033021.1|AYN65209.1|138819_139671_-|ribonuclease-III-family-protein
MGIEEWQEYIYQIEYTIGYSFKNKFLLYQAFTRSSYSNQYGVENNEVLEFIGDSVWSFCVVQLMAEKFGFLKSASQYYNKYEDLEEYCLIANENESDFTDLKNQIVSNKTLAKKINKLGFAKYLVLGDNDKRNNVANQDSVKADLFEAIIGAIAIDSGWDIKRLKNIIIKMLDIEHFFRDVDCREKRPNKFKLENAINTLKELAERGECSMPIYQISEKPIIDNNGKQWWHCRCNVNFRNLQWMGCLWTKYTEGYGTSKKLAKKMAAYNMLCDHYGLPNEYKN
>CP033021.1|AYN65695.1|137271_137724_-|hypothetical-protein
MVAKLWRLNKRWLDFYAYNSYTYPIDKFLNNKEAKNKYEYDYKKGAYYYKATENIKNNNPVIVSTAKTMHAFIIYGYDEETQMVLLNWLWGNNDSIVLVNYWKLAASGSPLKIIFTMRPKANQNLVTKKLFNYKNNMHTGEEMRKLINEN
>CP033021.1|AYN65208.1|136433_137285_-|hypothetical-protein
MMKTKKQLLIFLPYLILLGGFTIYLLISSIILKVDGEIDNTNLFNLINQIFLIAPSYTTQLLLMLLSIGLFLNIYFAKRYWTKHNIELDFKEKRKTYLIIILTTIIALISVFLINIMILFINQSYYRIRDGRDHSKIPVYLENTKIIEYFYVYIFRLAYWFLLSFLLIKITNNFKKAILFTFVIVLVYLISLILGTLFYQISHDRFLNYLIIILSSIVFPEILNSIYSLSNITMTLGSLYNNIYLINLVYIPAFVLFIVLIAKIKEKNFIFFKKFNTIKNKKL
>CP033021.1|AYN65207.1|135480_136131_-|hypothetical-protein
MICSRLLLPLNDIDEYKLIPLVRTIEFTIYIKASKIKHDNEVLLTSISNNLSQYDIDNFQGLYCDINQAFVADNQLFDEETEYQFKFSNSNDEDNYQASYIIQKLIKKLLNFVNDEDLNYCFIIMTKIQNNIIKPFYIYCNPEDAKKELEQLFKTLDNTKYEALLLEAANTFSFELKKFNEEYLNKSSWFYNYIHNQMSLWIEKANDIIFKKLKNN
>CP033021.1|AYN65206.1|134536_135382_-|hypothetical-protein
MKKNKKQLLLFLPYWILLAGFVIYLLISAIMLKIDGQIDQFNLFPLINQIFLIAPSYTTQLLLTLLSIGLFLNFYFVKRYLSKRSIELDHKEKRRNYLIIILTTIISLIVIFLINVMILFIKQNFYEIVHRHWNTKTPVYLENTKIIEYFYVYIFRLTYWFLLSFLLIKITNNFKKAILFTFVIILIYLISLVLGILFYQISHDRLTNYLIIVLSSIVFPEILNTLFSLSNITMTLNPLCNNIYLINLVYIPAFILFIVLIAKTKEKQFIFFKKVNYLKNK
>CP033021.1|AYN65205.1|133898_134498_+|30S-ribosomal-protein-S4
MSKFVGSMFKKSRRYGISLLENNKEFTKGKKRTTAPGQHGAKRSKPSDYQLHMYEKQKVRYMYGLNERQFKNLFIKVSKKAGVTGINLLQTVESRLDNLVFRAGFARTRAQARQLVNHGHFTVDGCKANIPSMIVKVGSVIELKEALQNNVAIKDAIEVMTVAPWLTKENFKVTFTRLPERNEFAKDINESLIVEYYNR
>CP033021.1|AYN65204.1|131325_133488_-|hypothetical-protein
MKKITKLFTAVAAGLFPATALISASCSTTENSKYGFDQDDDGQLVLATGFSKSNWQGFAIQGIVNTYNNWINDPKFKEERKQAGYLPLKISWLAAGYNTSSVALDLETKNRKDFHNILLNYASAAALYANHKMNLAVDDKDFKKYNIEPVFNNANSLIANNKDNKKWAIPLSRSGEITTIAKALVGKFVKELMALGVKLDSKNSSKLQSYLDYYNNNKQEAEGVDSIWAYSKTTPENLKKLTPEILHDLPIMSDKLFDNYSDLINFAIQAKRLYNVDPTLNVLGIDEIPSAINVMATSIIGSDINKNYINPDDNCPATGGYNYDNFIENPNSPQAKLFKKVSSIILKGISENAVWVAQPGVYGSSIFTGYKMAINIGSTAGYRHTFVGNNEKNSTYIIKQANRVLDPTTTIEILNNTPKNNEKWLLKFKQLGVKYPNTIWASDASEKDIKDAKQNPTYIKRISPLSINEAKKLQGKAGYIVSGSEYSYNKAENKIELKIGNKITKLQGIYLGKFFNNNENEYFFINQEDVDVKVLKANNFINQEDADWIAAPYSYSNNDKYKGIILQGPSVIPVHANKREDKATRLFINWMYTQPLNNLELNKVDSNGKKTNIQKFPDGTKAIDAFNAFGGYISPTNKYLSQDAKSATKNIADEIAFTNFKHLINEGSIYKPADDIATRKGDQLRDAIKQAARSILSDANVLKVFDYKDFINKIKLLFQE
>CP033021.1|AYN65203.1|128924_131066_-|hypothetical-protein
MKRLGKLFTLMTIGLLPTTTLILSSCSTTENSKYGFDQEDDGQLVLAMGFLKNDWQGLAIQGIVDTYNKWIKDNNKQSEGYLPLKISWLASGYNTSSIALDLKVKNRKDFHNILLNYASAAALYANHKMNLAIDDKDFKKYNIEPVFNVANSLIANNKDNRKWAIPLSRSGEMTAVAKALIGKFVKELMALGVELNSQNSNKLQSYLDYYNNNDQEAKGVDNIWAYSKTTPENLKKLTPEILKELPIMSDKLFDNYSDLINFAIQAKRLYNADPTLNVLGIDEIPSAINVMATSIIGSDINKNYVNPDDNCPTTGGYNYDNFIEKPDSPQAKLFKKVSSIILKGIQEGAVWVAKQGVWGTGIFTTYKLAMVITSTAAYHYTFVSENGKNNNYTIKQANRVLNPNTTIEILNDTPKNNEKWLLKFKQLNDKYSNTIWTADASEKDIKDAEQNPRYIKKISSLSTKEAKKLQGKAGFIVSGPEYSYNKIEDKIELKIGNKITKFQGIYLGKFFNNDNNEYFFIDKKDVEVNALNTNNFINQEDVDIISPPYSYSENEKYRGIILQGPSVIPVHANKREDKATKLFINWMYTQPLNNLKLYKDSSGKNVQTFPDGTKAIDAFNIFSGYISPTNKYLSQDAKSVTKNIAEEIAFTNFKHLIKEGSIYKPADDVATRRSGQLRDAIKQAARSILSDANVLKIFDYDEFINKIKLLFQE
>CP033021.1|AYN65211.1|143469_144063_+|FMN-dependent-NADH-azoreductase
MAKVLIIYGSVIPRENSISTKMLDLFVDEYKKNNINDEIKILDLNNEDMYSLTDKNFKLFYSEENSDKYINLLKSVDKVVMNAPMINFNIPTIIKAFFDRIAVANKTFSYKYASKGSSIGLLNNLKVQIIATQGAPLGWYPWASHINYLEGMWKFLGANLSESILLAGTKVEPLNKMQPQEIIETISKEIIKKASIF
>CP033021.1|AYN65212.1|144165_144609_+|50S-ribosomal-protein-L11
MAKKVVKKAKLQFAAGQAKPGPALAGVGINMPEFTKAFNDKTRERGNEPVPVLITVYEDKSFEFKLFTSPTSYKLIEAAKIKKGSGVANKEKVGSITIDQLRAIAEYKLPDLNTTKIDSAMKQVAGTAKNMGITVEGYDEWLKGSAN
>CP033021.1|AYN65213.1|144608_145301_+|50S-ribosomal-protein-L1
MAKRITKNIKNVKSLVNKKDVFPLADAIELAKKASFAKFDESVDIAIRLNLDTRKSDQQLRGSVVLPHGTGKSVKVLVATDEVSAQKASLEAGADFVYSSAELPEVLNQDKYDFDVIVADPKMMLVLGKFGKKLGPKGLMPNPKTGTVTINPAKAVEELKKGKANYRADKGGIVHASFGKKSMETNVLAENADTIIQTIKRLKPQTVKGTYVLNITVSTSMGQSVKVRID
>CP033021.1|AYN65214.1|145410_146784_-|phosphopyruvate-hydratase
MSKIIKINAYEVLDSRGNPTVKVELNTELAYSEALVPSGASTGSKEALELRDKGTKYENNWFGGKGVQLACDNVNNIIAKAIIGKEVSKQEELDNLMINLDGTETKSKLGANAILAVSLAIAKAGAIEANLPLYKYLAKLNNQVAYKMPVPMLNVINGGEHASNTIDFQEFMIMPIGAKTFKESLQMANFVFHTLAKLLKQAGHGTQVGDEGGFAPNLHTHEEALDFLVNAIKVAGYNPATSGEKAVAICLDAASSELYHSDTKLYVFKKFKKAIEEKRPGFEKYQNVKYSFTSDEFVEYYGHLIEKYPIISIEDSHDENDWDGFIKMNKRFGNKVQLVGDDLIVTNPKYIQMAIDKHAINASLIKINQIGSLTETFKAITMSQKAGFVAIISHRSGETEDTFIADLAVALNTGEIKTGSLSRTDRIAKYNRLLKIESELGNEAKFEGKNSFYNLKN
>CP033021.1|AYN65215.1|146987_147701_+|hypothetical-protein
MNNIDNNLFFIEEEIKKIEKIAKEDPLKAIYVLDEDKKQFSLKEDLDDLDALRDNIEFQLKKQNLITSTKLDTLSLINSLKNKKMGYAFMLSYNELKKRDDIAKYAIEFQDFFKGNDFDSKGFQTLIYDLLVNSNIDFEYDIQNKKINPKKLGSLLKNAEIQKMQDEIIATFDKDISKNKVARQVFSAYLFQNWVAILLHETKDDYLKISHVIEVILGNQTSDSLSKEEKELYNIFK
>CP033021.1|AYN65216.1|147743_149174_+|trigger-factor
MSRTLNKKESELTIEYTIQGEQWENAKEKARKALRANVQIDGFRKGHVPAFEADKRINPIEVYQKALDSILDNIYKEQIISQITKDDEIVGHANLRIKDINEEKAEISFVFPLFPEVKLGDYKKLGVKLGSCELTKKDLNDAKSQIASNYVVMLDSKEPIKEKDQVNFNFKGFIDGKPFDGGEAENFDLVIGSKQFIPGFEDKMIGLKAGEEKDLDLVFPEDYHAKNLAGKSVVFHVKINFVKTPNYPTIDDNFVKEINLPNVKNVAEFEEYVKFIALKNKLANVKNEFINEAVKKLSEQSEVSLSESLVEEEADKYYQNFLNNLKQQQITEKDYYEFSKSTKEESLNVFKKQAQINLKQMFVLGAIAKAESLKVTLEDYEKEVEKLAKTYGLAPEHVKQILKFENVENNLINERISEILLKENDTKAFENFDKLLKEVEEYEAKQTQAIVDEAKRKREEAEKIAKESKENIDEQK
>CP033021.1|AYN65217.1|149265_151860_+|preprotein-translocase-subunit-SecA
MKIFEFKSTEMRIAEATLKRINALEPEISKLSNEELQQKTIEFKSRLKAGETPEQIRPETFAVCREATKRILGKRPFDVQMIGGIILDLGSVAEMKTGEGKTITSIAPIYLNAITGQSVIVSTVNEYLAERDAQEMGQVFNFLGLSVGINKSQMSSELKREAYACDIVYSVHSELGFDYLRDNMAMSKEEKVQRGLDFILLDEVDSILIDEAKTPLIISGGDNDESNLYTIADLFVRTLSQDDYFIDEETKSVYLTDKGIEKANKYFNFKNLYDIENSELVHRIQNALRAHKVMKLDVEYIVRNDKIELVDSFTGRIMEGRAYSEGLQQAIQAKERVEIESETKTLATITYQNFFRLFKKISGMTGTAKTEEKEFIDIYNMRVNVVPTNKPIARFDDKDEIYVDMHSKWKAVTAEVKRVYKKKQPILIGTAQVEDSEILHEYLLSEGIPHTVLNAKQDASEAEIISKAGQVGAVTIATNMAGRGTDIKPSKEALELGGLYVLGTEKAESRRIDNQLKGRSGRQGDVGYTKFFLSLDDQLILRFSVQDHWKEIFKEYGEDPIPGEAIRKAFLRAQKKIEGFNFDNRKSVLNFDDVIRQQRDLIYEQRDLILNRDDLGTIIRKMISVAAEKTVNNPFFIKNNSLDLIEFVKHLNNNFMILTNKEFSVEELVEYDREELIQYLIETWNKCYDQLRQNIIDKYGISSLINSERNIILSVFDAAWQDHINIMDRLRRSTNLVQYSQKNPYQVYTQLGSKKFKELTDRIALESTINLMNNYDAIPSTNTDVDLSWLTNAFEEKTDMAQTTSKNQQALEFINYLLKSERDHLIKEGLNEQEVDDKLKEVERSILKEFQFQLASLQTNEEKK
>CP033021.1|AYN65218.1|151868_152300_-|NUDIX-domain-containing-protein
MKKEKSCGAIIFKEENDNLFVLLVEQTAGHWGFPKGHVEKNETEEETAIREVKEETNIDIKLLKGFREVNKYIIGKLISKEVVYFIAKPTSFDLIKQDSEIKVVEWQDTTNALLYRITYESDCEILKKAVEFYCEYITKNNGF
>CP033021.1|AYN65219.1|152386_152890_-|hypothetical-protein
MDINNIIKNNIKRLLITTAFGFLAILISFLITGIFSIQSLSNNSRLTISCFGQIICGFYVVYYILNFFLAYRFKSEIANKKILKTLLIISIFILICGICFIVNGLILPSIRKTYIQAITTRNNNLLQSILWQGKVIKVEMWISSTIFLVAIASSLILCSFIFKKMNN
>CP033021.1|AYN65220.1|152973_154977_+|DNA-polymerase-III-subunit-gamma/tau
MALTNKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDILKPCEECIKNVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQLFGIVNIDNKIELLNCMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVSTDFKILLQIKIDDAKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNYLSPKEEYKNSAVMPKISNEEFNNFNSQEKQVINKNNIYKSLDLSSIANGFNANNSTIQNSSDNNSTEDLANNSKKIDDLLEKTAEIYSLDQTSEFEVADISNQIISNNQISIDSNVDNQETADLQISENWKDLVNEDLISKENSENKHVPLETIIDCLLIKQYLKNNMLNDGRSNFTDIDAIKYGMLSQKITDKNEINILSDFKIIFSTNDFILLTCDIDEKVYDLNINSHNENIMSALNKVFDRYLYAYAITKGEILEAKKYWKENINEIRAKKVKPLEDLNLKYNKTVQKDVAWAQEIFGDKFKLNK

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Crispr_ID: CP033021_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033021_3

300449-300672

Orphan

Consensus_repeat	Method
CATTTGTTTTCAATTAAAGATTGGGTGGCCTTGAGGATCTAGTTGGG	PILER-CR

2 spacers

The CRISPR arrays of CP033021_3

>merge|CP033021|3|300449-300672|PILER-CR
AAAGATAGGGTGGCCTTGAGGATCTAGTTGATTATATTTAGAGATGTCAAGCCCTTGTTCTAAATCTTTGCGGATTCGTTCCATTTGTTTTCAATTAAAGATTGGGTGGCCTTTATGATTTAATTGGGTGTATTGAGATATATCAAGGCCCCCTCTTAAACCTTCACGGATTTGAGACATTTGTTTTCAATTAAAGATTGGGTGGCCGTGAGGGTCTAGTTGGG

>CP033021|3|2|300449-300672|PILER-CR
AAAGATAGGGTGGCCTTGAGGATCTAGTTGATTATATTTAGAGATGTCA	AGCCCTTGTTCTAAATCTTTGCGGATTCGTTCCATTTGTTTTCAATTAAAG
ATTGGGTGGCCTTTATGATTTAATTGGGTGTATTGAGATATATCAAGGC	CCCCTCTTAAACCTTCACGGATTTGAGACATTTGTTTTCAATTAAAG
ATTGGGTGGCCGTGAGGGTCTAGTTGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP033021.1\|AYN65355.1\|311652_316386_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65351.1\|304399_304807_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65350.1\|303626_304385_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65345.1\|296689_298393_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368653
CP033021.1\|AYN65343.1\|294976_296182_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65349.1\|302716_303616_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65354.1\|309852_310644_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65342.1\|292936_294958_-\|DUF87-domain-containing-protein	unknown	unknown	gnl\|CDD\|274279
CP033021.1\|AYN65344.1\|296183_296546_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65340.1\|291342_292125_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65348.1\|301051_302218_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65346.1\|298820_299330_-\|sugar-phosphate-nucleotidyltransferase	unknown	unknown	unknown
CP033021.1\|AYN65347.1\|299471_299663_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65356.1\|316468_317512_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65352.1\|305998_308299_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367119
CP033021.1\|AYN65341.1\|292176_292950_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223510
CP033021.1\|AYN65353.1\|308306_309548_-\|hypothetical-protein	unknown	unknown	unknown
CP033021.1\|AYN65338.1\|285323_290909_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378012
CP033021.1\|AYN65339.1\|290895_291288_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
CP033021.1\|AYN65699.1\|304979_305972_-\|DNA-(cytosine-5-)-methyltransferase	unknown	unknown	gnl\|CDD\|238192

Protein	Function_ID	Function_description	E-value
CP033021.1\|AYN65342.1\|292936_294958_-\|DUF87-domain-containing-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	9.31139e-15
CP033021.1\|AYN65345.1\|296689_298393_-\|hypothetical-protein	gnl\|CDD\|368653	pfam05887, Trypan_PARP, Procyclic acidic repetitive protein (PARP). This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.	0.000560418
CP033021.1\|AYN65352.1\|305998_308299_-\|hypothetical-protein	gnl\|CDD\|367119	pfam02534, T4SS-DNA_transf, Type IV secretory system Conjugative DNA transfer. These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.	9.98401e-35
CP033021.1\|AYN65341.1\|292176_292950_-\|hypothetical-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	1.3316e-06
CP033021.1\|AYN65338.1\|285323_290909_-\|hypothetical-protein	gnl\|CDD\|378012	pfam08496, Peptidase_S49_N, Peptidase family S49 N-terminal. This domain is found to the N-terminus of bacterial signal peptidases of the S49 family (pfam01343).	0.00334019
CP033021.1\|AYN65339.1\|290895_291288_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	1.60665e-19
CP033021.1\|AYN65699.1\|304979_305972_-\|DNA-(cytosine-5-)-methyltransferase	gnl\|CDD\|238192	cd00315, Cyt_C5_DNA_methylase, Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the mammalian genome. These effects include transcriptional repression via inhibition of transcription factor binding or the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability.	6.41902e-54

>CP033021.1|AYN65347.1|299471_299663_-|hypothetical-protein
MSKYFYRLRGSQSTGKNAKTYSFGSAQQYNKALIMAQDAISKNQFKEVQIERIQVIKIIKQNS
>CP033021.1|AYN65346.1|298820_299330_-|sugar-phosphate-nucleotidyltransferase
MSIDDEWYTQEKDIKYFLENFKIDKKKTIWCPFDTQQSNFVIVLKSLGYKVIYSHIDNGQDFYKYEPNENYDLIISNPPFRNKANIIKRLQELNKPFALIFGVQCFNSGGFVSQLQKLKNLELVFLTKRIKFLKNYKQDLKNIPQPTFHSLWICSGITNKPLSILEGVK
>CP033021.1|AYN65345.1|296689_298393_-|hypothetical-protein
MKKSKRILLTIGSTIALTTLPIMAMSCEWLDKLINKNNPNPTPTPGPDSGLVNPNPKPQPTPPSPVPTPEPKAEEKEGYVTYKSTNEDYLKKNNTYYFSKLLYDPVDLSDEVYNSQDWKLYRPKMWFSLTNKPENETETESKLEKQLDKWHMSLDNVHFTNDCESACGIWNIIRKLAESDENKEGINQGGRFKPKDNESYNEALMRFLKEMDDYLDPKYAFRGLTKDKNHIAAVNQNLAKDRDWISKKLIYSADSKMPSTFIKENFIENSFDDIAKTNQDPFVKELISDYEKAMYKGWIFENKAKNWFVAPFSFGSNPTMRNKFPDQTFNMYTDKNGLDKTTPTPAYNNYNPVAFNFLVMERFDLSERLNFEVYKNLIQWLISFNNINSENKSKWSEIENDKKIQLKNASTDLVKALVKFIDWHHLLLGEFENPDDKHSTLADLFAMKSLTMGDKIDFDYTYRFAYKFLYEKLVPTMVANGWNMPNEFKNLEEDMLDRNKKDSYIYDYIFKYINVIFKAKYNDIDEIKKPNGYLDLNNKEHWQKLFLDNVLKKWNSAFNINVDLKEF
>CP033021.1|AYN65344.1|296183_296546_-|hypothetical-protein
MKIDDKSFSFLGNFSETIMRSIFIALIPVAIILLIGMILWARSQNAATKDPNERKQNNLKVWGALSALIILVVMWPLIELIKANVKKPSNVGSQASLFTHAILNNFTISIPKLTNFNLMV
>CP033021.1|AYN65343.1|294976_296182_-|hypothetical-protein
MGKFLEAIINPIINLIATPIRLMWFVPLAAIGLIGFTIFNLLFFLFKLFSLDLNNYLMFNLLPGQSYSQFSVARPWYQFLIISFVLWLINFFVFVIRYSKESNGLKAKEIFVQALKSTVGGVLTLILFQVVILFINIIFIELTKALYGDYNDFFNFGFGQISNNIIRNMMPPQAFVPDKYWDPFPYGSPIANPLWGLGFPAWWDWTKNITGYALTIGLSIAIVGVLISIPLIFVLFDIISRVFINWLLFISFPLIPAFSINDGGKRIRVWKEKYFGNLLSCSIYGVGIMMLGSFIGLANTFMTSATNYMIGAFSSLSNFTTIKAVLALLSTCFLVIGSAFAFKKLSEMAIAFVGSEVSGGQSARLAMSGARSGAGAYKTVKDAALRGTNVGAAYKVASFLK
>CP033021.1|AYN65342.1|292936_294958_-|DUF87-domain-containing-protein
MTQLQPSRIKHRSSKIWKTFKTKDLIEFVVILLLSFFISFGFSQLINVKLIFFAFWIPTFLLGIILIMPNRKNNCKVYVLIWRMFVFWTIPKRFVKNVQNNSFRSSLDLNPYSCLVNEYVVKNKNSKISFYNPRNDKENYLAVFKLNGLNIWNEDELTREAFIDSFAKTLNILTYKVSFVKLEEKVNYEENIKYIEAKQAKQINNNAMWNNYYDLNIKDFSNLNKEAISNNFYLIVNGENLNDLNEYLEVIIDKFQDTGIGLEKLHKARLLTFLNKLNMFGIDSQNIQEYCNDLDAKFGVENSLDNLFIYNQVIIRDKYLQINDNYVKINCLNKLPFELSDKWIKTLFSINGTCIWNNFPWNNNFANKKMDKSMMASIDTTNATGSVSANLVGSIDEQATMAMMYQVNKDEYKLFDSNFFFVSKATDLAELNRQHRIARNIASKKNISLNDLKYRQLLGLSEACNYPFERLEREYYQITSINLALGWPFETENHNDSNNLLLGYSEATRSPLSFRLFDMYHSNRTNFNMFINGTSGKGKTTFTMKLLTSILAANNKVVVIDPQGEYRELAQKLNGQIIDLGAGKNTIINPLQIRNSLKDATGNDTSSLINNHLSWLESFFKVLINIEDHKWILLQNVIKEFYEDRGIYKLASIEQLKAVEWPTISELIKYVQL
>CP033021.1|AYN65341.1|292176_292950_-|hypothetical-protein
MSNYKTLHLNNPEAKRAILVELCESFSFLFENNGRYQNLFNGHTNIKLDNDFVVFNTQNLINGADNIGAKLGTMCLLNFVSEIVFNNWMHNEMLKKKYLQEHNIKLMDAKQVEDTIRFCAVIVDEAHLYIDPDNPAILKYMVQMTKTVRKFNAGMIFTTQNPGDFTVNNATSDDASRIIQNCQYSVFFGLKDQDIDKVQQLFKNSNQLLQSEIRYLVNARYGKCLFSISSNKRIRVEIYYNKLEQELFFKFLNKEWI
>CP033021.1|AYN65340.1|291342_292125_-|hypothetical-protein
MKTNKNELDQDFDNLDNNEILSNDNQTQNEDDFIENINLTSDNQVNNIMNSITSSQPKKQKERKQQNNFEAQFSGRFTDPEDVGMFYRWKKELEKNGKTVYKELNNVIRSYLLANEKKEIMRDWKHDLFQALRKVSWSALSPYQLQINRRFRSMDIEMSIINLKLNMIINALFKDNGDLEKQIDNPGADILAESKFFERTIRGAVNKLTNDWTKKMANKIQNSERAWNDFLSSLSENEFDDILQEIGATNSTAQEQIEEK
>CP033021.1|AYN65339.1|290895_291288_-|single-stranded-DNA-binding-protein
MNKVILTGRLVNDNWKPFKSEKGQALPFVIALFEQANKTNFIEITCFNKLAEHVMKYVKKGDLLEVVGKLHNAKFSSKNNETIYKTEIIAKNITFLTKSKSNIQPISKETNSENNEKDIFGIDFFEDEEN
>CP033021.1|AYN65338.1|285323_290909_-|hypothetical-protein
MKKIKKTLLIAGGIFSIASASLFSLSFSRNEHYSSYKYEEIDKDQYSFLNNKNLLKSFFTNLTYRKDSRQDSFIFDPKDYSSNPLYCDQRFIANTNDRLEFLKELSINDINKINNQPFGDYKITLENNANEPSNVGNTDPEEYNKLPSQIPSWLQGYEKYVSSLTEGWISEGDIIPGELEERYPNAWNPGQIIQTIKKSNYSINWVNAQSFKKLTKDYDIKIKTFNNRLSDPKINSSDIAHSDEAYIAYDKFKLSYNDHLEVNYDFTKWHGIDLEDAYSLICFLANYNNFKHFQKFMLAFHLQNSSQEIVIDSDTMGKLTTGIDLNIFKGGKSNLEKLQEIAKQMDNETSVGNFIIKYGYEVKPISDGNHFNLIFKIKQLKYKGKDITNSFASKIFNEADTYNFANNFAKNQQSKIQIKNLYNMFYSLFKGKTIMANVPVRFTPSQIYQTYADKTGFVSRLWFKYGVVLNQNNLSNIQENHSFNFKDNLQEDKPIQLEPANGNYGGKWLVHTPLQVNFDTTLEENEVLFINGQKVDVLNRHFVYHLKDLRRSASDEEKIALEKNDSNKPQEELNDHNSRKKNEYIVEIKKFKPGTNNSGEPIATYKIKFVIVEQPINQSFKWFAWDPENNPKQKELITKEITKDGRILVDKEGNPLPNPKYDPTIDPKTGTKNQLIWIKNGTLAKEITKNLKFWYPDIKMLNDFGIFAEGAVLGKGALRNLILDKNIAKKSNVTYYKCKLYDKGSNKWLSPSEIKPEPLSSSNGNSENAYMSEEGIWIVYAATSTSISNIKLVLIDESNSPKNLFWQELENKKDNYGIDLMKKFEPFWQSTLGIYFKKWLIESKHYDKEQLDKLTYDELLPLYNECVNSSWKFADNDNSSIENAINIFNDFKWSKLQNFNGLTDKQAIKDKVLEYIRTNMSSNALTKNLIENKDWFISEFSNITEENKFLEELANVSIYGTEQNQNYEGVKLTLIGKGLYANSRKEIYFRNEAWHVYNPPIDLSTLDIQNEFILNVSKKSFEEKNIPEDVIDERYRKAIEKEVINFITNQLLQYQLKTKSSGKEIEMLLNKDVEIANLNEVIAHLMRGKALSSFVGLKLVSKNANLHNYKIINFKNLGEGGKFNLRNLSYILMDNKNVIQETKPSQIRKKVIEIVVNAASKLGLEINNDYQIFAINNDAYWLELVSKYDDPKLKQNKEFYEKLQQALKALQLRKTFKYEGKDKEIEFEPKDLDLKNQLEQYKNSIIEELEREIYNNSLNLEVLYKKILLLPTNKTTGFGYGYIINKANKEYNPAIDPEWKPNPNPDDEDKAVNIFNDFKWSKLQNFNGLTDKQAIKDKVLEYIRTNMSSNTLTKNLIENKDWFISEFSNITEENKFLEELANVSIYGTEQNQNYEGVKLTLIGKGLYANSRKEIYFRNEAWHVYNPPIDLSTLDIQNEFILNVSKKSFEEKNIPEDVIDERYRKAIEKEVINFITNQLLQYQLKTKSSGKEIEMLLNKDVEIANLNEVIAHLMRGKALSSFVGLKLVSKNANLHNYKIINFKNLGEGGKFNLRNLSYILMDNKNVIQETKPSQIRKKVIEIVVNAASKLGLEINNDYQIFAINNDAYWLELVSKYDDPKLKQNKEFYEKLQQALKALQLRKTFKYEGKDKEIEFEPKDLDLKNQLEQYKNSIIEELEREIYNNSLNLEVLYKKILLLPTNKTTGFGYGYIINKANKEYNPAIDPEWKPNPNPDDEDIVSPEDIPKDPNRIKKVVKTWWFPLVVIIGILTFLVASIFIIKSLLRKYGWSFGKRAKRIRRQNPNKQSYQEKHSNKRQEKLAKKEAKNLKRQTRKQEKASLKKAKKDKKTKNNPKINNEQNSIN
>CP033021.1|AYN65348.1|301051_302218_-|hypothetical-protein
MISNKKLLENFFFPLEPNPNDKMETFVIKSDGIEYNYQFPGFINFWLYGQNISTIFMDLSVEWPNINYEVNQENIIFKFKANQQANIKGFSNTEEFCIAQNSNVEISVPCYKPFSVVILEQIDSLHEKISIFNYLNQNNFNLAQIKAIYKNYHYYYKHILFRDKTFEYLDNGIKSVDLDIIAKDFEKKINNLATYNSTLNEWNDVDWEKIKLYWSPDYKNNVQNHFANKLFELQQGNSKLNFEKYFCKFKKIDDSYCVKKFYDADQMHLIRTSLNQEFNVLKYVNTSYDYHQIEQIWLGLNSGLDVSIYAKQNSFNRPIFNWKQMEQIRIGLEHGLNVSKHTHLAPKSSLSDFDKTPTDLQDSKVINEYNKSSHTPSDTQSKSHSLTK
>CP033021.1|AYN65349.1|302716_303616_-|hypothetical-protein
MINQNQELEKFLFPLETIGWAKPKIFLIKINDNKYKYKFKGFDDFRIYSQNLSKIFFDAGVNWSNVDYKINKQNTIFSFKNNNDFEIRGYSNKNSIEVPQNSKIEISVPIKKVYTKEYILDSLNVQNTKFQIYEYLKQNNFNLNQIETIYSNYHDYYKHILFRDKTFEYLNNKINVNDLREIAKDFEKKLDIMALRKAIEFNKLNPSKISEDEINYRKYWIKQSSDYKNIVQDHFANQFLNQCLDLSKYTHLTSKSSLSDFDKTPTDLQDSKVINEYNKSRSQSNQNKTLESKNINRCI
>CP033021.1|AYN65350.1|303626_304385_-|hypothetical-protein
MEIKPFKMNDISYMTQYDDIWYSDRKVLNYFNNTLFSLNSEEEQKLYKEQICQISKQMEKSDDFVNKWIYDKLITSETRPNYLEGCSNIINTLSSDNWINESDWLKYPASQFMEENDIIRKDNLEEIIDVDLKTNGYESQWINGTTKFNVLNNLSNEEYVYVNPYLEIEPINIKEIKDDYIEALKTFDLDDLLESRDEKSLINLDSNESSKSSLSDFDKTPTDLKDSKVINEYNKSSHTPSDTQSKSHSLTK
>CP033021.1|AYN65351.1|304399_304807_-|hypothetical-protein
MTFEELHKDLDYWKEHEPQDVWDYYLAYDLADQEFKTKGIEAEGWAFDIEDIISINRIYDVEYIAINEYGRAMVISVEDAGRFFQNQEIEENESSKSSLSDFDKTPTDLQDSKVINEYNKSSHTPSDTQSKSKTL
>CP033021.1|AYN65699.1|304979_305972_-|DNA-(cytosine-5-)-methyltransferase
MKVVELFGGIGAIRKALIRTIKPPNFEIIDYVESDKKTVNAYNAIYNDFYKPLDIRDYSLPNNINVDLLFHGSPCQDFSCAGKNIGGSKESKSRSSLLWETIRIIKEAQIKPKIVIWENVKNVLSKKHKPIFDAYIKALNDLGYVSHYKIINSLDCGIPQSRNRVFTVSINKNYLKQFNNLDTFNCLNNKYKNINDFLQPNVINPKYFIRTNCPSMINAITNHKIKIIENKVFTITTKQMRWNNQGVVKVEISKVPNNSNLAKMIIDNKPYYLRVITPLEAMLLMGYDQQDYERIKNFCDSQIYKFAGNSIVVNVLQEIIKHIFKLTKEE
>CP033021.1|AYN65352.1|305998_308299_-|hypothetical-protein
MEEQEKLSKSKIIGKTLLSIIVSTFLFFVLTFIINVFMGQNKNPGHFKLFWNSTVTLLKTKPDIFVYIGLGISILVFCFIFWRQIKSLGKKISKYLFGAKASQNWLWNYQLGEGSKTKYNKLFRKMINAETEPNWLFTFDKTQKYWYVNDKDDNSIVNGPPGSGKTHRIILPNIEFMAQLDYSKKPNLIISDPKKEIIKFTGGLLTENDYKIYVIDFSDPKLSLKWNPLSYAWDLAVDGEKFKNLTFEERINKSLEVINNVIESLNWGKAVNGNMWISQAKKTLIVITNFLLLLGIDDKNIIHKNNFNFETIASLLNTSHWENDKNISAWILYAKKRALDDNNYYWKKVYNNIEDLSKTPKETFGGILAEAQSVLNVFNNDENLKMVLRDTESFNLVDIVSDPKPFAIFIHYPDHKPTSHFLVSMLVEQIYQSLIEQANKNDNLKLDRKAFFLLDEFGNLPVVVNFDNKLTICRSRNIFFMLVVQDYNQIKKYNIYGEGTAQVIKNSCQVVYFLASNDEQTLNDISKALGTKEVKSKSYTTSDNHSSSTESEKSKPVMEVAELKSKKPDDLIIIKNGYKPLLIKTLLAYKYFPNDNYVYTRNESKLLTNADFELFDIRSLEKLIKFDNSKQKKQNNKNQKVSEHNDLTNLEDVEDPEDLSQEQKIQRMKIVFGKLDLWNNYINLKNDYKRTLIPYKKNQIKEQIEETLSLMWEQYVANDLENDLVNILWSEAKKRKIPNYYDLKVDILLQLLHPLEDVSKLIEKSN
>CP033021.1|AYN65353.1|308306_309548_-|hypothetical-protein
MDKVWTEFNFITPNTMYKTKLGNTHDFKSWVNSGLVVDYITRPDKCVVFKEDENNYDAMKLLLTKEDKINWYRQHLKINQNSNQSGLYNLLDNDPKDVNLENVKNDLKNLKGNYWELIVNPGDLGLDNNVLCKDKWHEVLKPNFERFLKANSFDLENVNVFYSIHGNTDYPHVHMFWYEKEHKHKKAKLNLNSINVFGYKVGLSIKYDEDYQKINALTKDIWNTRKQIVGIIANNFANSNEVISKSNLCQEFIKSSKSILDEVLNKKNISYSRISDENKKNIETIKKFLLNYDNDYSKLFNSYQKQINDLNNLNIEDKFLKQRISKIINNEMDDFQKQVGNKIIKTLLNAYKQNNNAFTSRKNFASFFNEFLKIFSLNRSEWALRNLAEREFLAKDLKELELVEEFYRSKLVH
>CP033021.1|AYN65354.1|309852_310644_-|hypothetical-protein
MGAYSEFMVMQQEAKLNNDYSLVDAYKRNLNWRRNYSKKIYDKLSDIAISKILKSKIVISESYYQKLKTNKVLLEVFMVIKSFKNKKIKIIDLINLGFKKTSIKSAIKRLIEIKVLDGEFYKKYKLLKLKKIVLKNPKENYWILNGYDALKIFLLNGLSNAILYVINSHKSKQLNAKKLHCKINSKKVILQNAYYAKFNWSNSKIYLMNKAIANYFGVEYLQMFAILRSQEKKFITIKNEFGYSKIKFNGYKFSTQRYLLMQI
>CP033021.1|AYN65355.1|311652_316386_-|hypothetical-protein
MKKNTKIKSISILSATAILLVSGVISSACNKTQDKETETTKLKEQTRNIKPNLKLSIKQDNILPSEINLSNFYVDNLDKEISFEISNIIADDVNGNVIINYYFTKSIIDSKTRKPLLIKSNMFSQKYTGFKALVAPLNSSIEQVNLEINEFNKKDFLPSQYIKLQSNFSFKNIDSQYELKTEYIANDEQGKIEVKYYYVQKDKDIKSKIISKTFYGFNSLNNIANMQKEANTLNKLGNEISLKLKKQINKSETYASTLNWSDFETSKKLNSAYLRSNGELIFDDINGEVKLNYYFEKQYIDKKTGASYWIKSKVYTTKITGFKSFLKNLNIAVDKVNLSINEKNINTILPSQYIQNLDNFKFNNLNNEYELQKKFSYDDQKGELTISYWYNDNKKNLKSNIVTKKFVGFNTLLNIERQETSKKLSNLVNSIDLNEFLALEKHNKKPSEIKNVDFNRKNIDGAMLVIEKMQANNEDGTLLISFYLKSTNPKFSDLKTEIKTVKLTDFLTNAQFINNQRNETIAYLNELIGNLNIKVSDKKPETAIKRFASSIKQSDLNIEILKPNNHSKNIEVVVKQLISNDESGKLSIRLAIKQLNKQINEYCESSKLIEVELSGYKTKTMDKNEKIESLNNVAKETTTLRLISSKDIAKTFASDVQKNDFETKISNDFYIEILEISESNDDKGNLKIKFVVKTNEKQYKDLKSNEQTITLTGFYKKEQYLKARKQELNKLISDDKIEANLVFDKENDKSNILPSNVESKEIHLNISDSKYTIEGNPSIIADDDQGILSISWTIKVKEEKFNTFIVSESKISKKITNFLTKKQNEINIEQKRLDALVEQENIISLKNNEYLTSKKSSMISENDFELNKQKSNELAGLELNISEIKANANGKLEITFSLLNKTFKHGAKESSKKTVTFDFLSDENYAFNLINKLNISKESTYVTDGVYTEADFNNKIANNKQEIAKLLGISDFLNQNSIIELNQESTNAIVSLKKGANTTVKYEFILKIKSTNDKLFKKFSGEISIANIMNKRNLINFANKFDFDFKNDNKKELAKLMTIDESIKKDYNFFFEEKIDSGSGKESYIIDDYKIQKDYKLLASGKEDTINIQITFKLDDYSEIKTFTKSGFNDKTSIEKIKQELENEPKRLDDLLDKLTMEFTKANNDFEKQSIDVKDITIQDYRFNLKDNDFAAIYEIEAVKYDKTLGKLTYKIKLKSNKSLLNEYSKNPIESTKSRTFEFDGFVKDISEITKNLESDVKKSNEFKKYLENVKLNIETNIEKKINEARKKQQKQAARANVIKAIIEQYKKFNEEIEKTLFELANKAINVFGQFNSNKESIKKLYKILINLIINTNDEMLNVLLELGINDKVSSRGFLGLTYFINLARDWVLSKTVGAWAIKIFKEFKNGTDVFIEYLTPILNRLKEKYEFLKTNDSKYNELKSLLIEHLKYILDYFCNLKFDYLFHNEGPKQTEYDNKGGGKTVLLSGGWDVLFDVEKFIESKYSDPSGNDLKKKLNDMVNSNKITKQEYEIIFNEFKGIILIFKQLITNIYSKDLKNVLTSQLPKVFGAINDAKKSAK
>CP033021.1|AYN65356.1|316468_317512_-|hypothetical-protein
MKKSKKILLTMGVVLPLLASTPLVAAGCVKTEPEPKPEDQKNPEGGNPGTTPEKNPEGGNPGTTPEKNPEGEKPGTTPEVKPEEKSELQKATEGIADATVKANFESELKKYREELKTKSEEILKPIIENKEIKAAVSEKELPNITKTYNEAISKLNEILDDIILSTLKEYNTNKTKVSDGLMTIKNYLTKEKISDLIKKENGLADFLVAFGKNISKYAKSIFETLKTNESTKAIAQLNDLITAVDNKFAGKDNLFETTAKKLKGFDFSKLAEEGYVKTFEKLITLLSDAKVEAVAVLKSVKMSEEDIKKVKDVIRPIYNVLNEGLKNSINLFEQSLRDLPKVLEILK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP033021_2	2.1\|142942\|44\|CP033021\|CRISPRCasFinder	142942-142985	44	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	664655-664698	0	1.0
CP033021_2	2.1\|142942\|44\|CP033021\|CRISPRCasFinder	142942-142985	44	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1581498-1581541	12	0.727

1. spacer 2.1|142942|44|CP033021|CRISPRCasFinder matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 0, identity: 1.0

cttgcaccattgcggatgtagttcaatggtagaacatcaggttg	CRISPR spacer
cttgcaccattgcggatgtagttcaatggtagaacatcaggttg	Protospacer
********************************************

2. spacer 2.1|142942|44|CP033021|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 12, identity: 0.727

cttgcaccattgcggatgtagttcaatggtagaacatcaggttg	CRISPR spacer
atctttcttttgcgggtgtagttcaatggtagaacttcagcctt	Protospacer
 *. . *. ******.******************* **** .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

635291 : 643320

Mycoplasma_phage(83.33%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYN65590.1\|635291_636956_+	hypothetical protein	Q6GZ00	Mycoplasma_phage	3.6e-37	28.7
AYN65591.1\|636984_638394_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.9e-55	55.3
AYN65592.1\|638362_639262_+	ABC transporter permease	Q6GZ02	Mycoplasma_phage	2.1e-63	49.8
AYN65593.1\|639254_640094_+	ABC transporter permease	Q6GZ01	Mycoplasma_phage	1.1e-66	49.6
AYN65594.1\|640115_641876_+	hypothetical protein	Q6GZ00	Mycoplasma_phage	2.9e-45	32.1
AYN65595.1\|641973_643320_+\|tRNA	asparagine--tRNA ligase	M1PB22	Moumouvirus	4.8e-72	36.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP033021

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection