assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_901733115.1_Escherichia_coli_MAD	NZ_LR595691	Escherichia coli isolate EcMAD1 chromosome EcMAD	1	257587-257740	1	CRISPRCasFinder	no		DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	Orphan	CGCGTCTTATCATGCCTACAAACCTGTGCCGGATCGGTAGGCCGGATAAGGCG	53	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	NA|150aa|up_8|NZ_LR595691.1_247559_248009_+,NA	NA|451aa|up_9|NZ_LR595691.1_241294_242647_-	COG3515, COG3515, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]	NA|150aa|up_8|NZ_LR595691.1_247559_248009_+	NA	NA|257aa|up_7|NZ_LR595691.1_249447_250218_-	PRK10438, PRK10438, C-N hydrolase family amidase; Provisional	NA|158aa|up_6|NZ_LR595691.1_250371_250845_+	PRK09993, PRK09993, C-lysozyme inhibitor; Provisional	NA|815aa|up_5|NZ_LR595691.1_250887_253332_-	PRK09463, fadE, acyl-CoA dehydrogenase; Reviewed	NA|193aa|up_4|NZ_LR595691.1_253571_254150_+	PRK00414, gmhA, D-sedoheptulose 7-phosphate isomerase	NA|256aa|up_3|NZ_LR595691.1_254355_255123_+	pfam13230, GATase_4, Glutamine amidotransferases class-II	NA|247aa|up_2|NZ_LR595691.1_255093_255834_-	COG3034, COG3034, Uncharacterized protein conserved in bacteria [Function unknown]	NA|250aa|up_1|NZ_LR595691.1_256134_256884_+	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]	NA|166aa|up_0|NZ_LR595691.1_257059_257557_+	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|580aa|down_0|NZ_LR595691.1_257874_259614_-	COG1298, FlhA, Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]	NA|262aa|down_1|NZ_LR595691.1_259558_260344_+	PRK06778, PRK06778, hypothetical protein; Validated	NA|352aa|down_2|NZ_LR595691.1_260414_261470_+	PRK02406, PRK02406, DNA polymerase IV; Validated	NA|151aa|down_3|NZ_LR595691.1_261466_261919_+	PRK09831, PRK09831, GNAT family N-acetyltransferase	NA|89aa|down_4|NZ_LR595691.1_262225_262492_+	PRK09588, PRK09588, hypothetical protein; Reviewed	NA|47aa|down_5|NZ_LR595691.1_262651_262792_+	PRK08179, prfH, peptide chain release factor-like protein; Reviewed	NA|486aa|down_6|NZ_LR595691.1_262848_264306_-	PRK15026, PRK15026, aminoacyl-histidine dipeptidase; Provisional	NA|153aa|down_7|NZ_LR595691.1_264566_265025_+	PRK09177, PRK09177, xanthine-guanine phosphoribosyltransferase; Validated	NA|415aa|down_8|NZ_LR595691.1_265116_266361_+	PRK05077, frsA, esterase FrsA	NA|134aa|down_9|NZ_LR595691.1_266418_266820_+	PRK10984, PRK10984, sigma factor-binding protein Crl
GCF_901733115.1_Escherichia_coli_MAD	NZ_LR595691	Escherichia coli isolate EcMAD1 chromosome EcMAD	2	2383596-2383722	2	CRISPRCasFinder	no		DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	Orphan	TTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGC	39	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	NA,NA|105aa|down_3|NZ_LR595691.1_2388286_2388601_+	NA|395aa|up_9|NZ_LR595691.1_2362503_2363688_+	PRK05790, PRK05790, putative acyltransferase; Provisional	NA|259aa|up_8|NZ_LR595691.1_2363761_2364538_-	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown]	NA|550aa|up_7|NZ_LR595691.1_2364542_2366192_-	COG5445, COG5445, Predicted secreted protein [Function unknown]	NA|1465aa|up_6|NZ_LR595691.1_2366192_2370587_-	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only]	NA|208aa|up_5|NZ_LR595691.1_2370730_2371354_-	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown]	NA|563aa|up_4|NZ_LR595691.1_2371350_2373039_-	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown]	NA|876aa|up_3|NZ_LR595691.1_2373187_2375815_-	PRK05560, PRK05560, DNA gyrase subunit A; Validated	NA|241aa|up_2|NZ_LR595691.1_2375961_2376684_+	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	NA|1251aa|up_1|NZ_LR595691.1_2376811_2380564_-	PRK09752, PRK09752, AIDA-I family autotransporter YfaL	NA|762aa|up_0|NZ_LR595691.1_2381259_2383545_+	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha	NA|377aa|down_0|NZ_LR595691.1_2383778_2384909_+	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed	NA|85aa|down_1|NZ_LR595691.1_2384908_2385163_+	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein	NA|217aa|down_2|NZ_LR595691.1_2385216_2385867_-	PRK09902, PRK09902, lipopolysaccharide kinase InaA	NA|105aa|down_3|NZ_LR595691.1_2388286_2388601_+	NA	NA|359aa|down_4|NZ_LR595691.1_2388819_2389896_-	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional	NA|453aa|down_5|NZ_LR595691.1_2389900_2391259_-	PRK11273, glpT, glycerol-3-phosphate transporter	NA|543aa|down_6|NZ_LR595691.1_2391531_2393160_+	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA|420aa|down_7|NZ_LR595691.1_2393149_2394409_+	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]	NA|397aa|down_8|NZ_LR595691.1_2394405_2395596_+	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	NA|300aa|down_9|NZ_LR595691.1_2395788_2396688_+	PRK09956, PRK09956, ISNCY family transposase
GCF_901733115.1_Escherichia_coli_MAD	NZ_LR595691	Escherichia coli isolate EcMAD1 chromosome EcMAD	3	2888851-2889429	1,3,1	PILER-CR,CRISPRCasFinder,CRT	no	cas2,cas1,cas6e,cas5	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	Unclear	CGGTTTATCCCCGCTGGCGCGGGGAACAC,CGGTTTATCCCCGCTGGCGCGGGGAACACA,CGGTTTATCCCCGCTGGCGCGGGGAACAC	29,30,29	0	0	NA	NA	I-E:I-E:I-E	9,9,9	9	Unclear	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	NA,NA	NA|254aa|up_9|NZ_LR595691.1_2880663_2881425_-	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional	NA|350aa|up_8|NZ_LR595691.1_2881405_2882455_-	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|160aa|up_7|NZ_LR595691.1_2882451_2882931_-	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|237aa|up_6|NZ_LR595691.1_2882930_2883641_-	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|104aa|up_5|NZ_LR595691.1_2883659_2883971_-	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|108aa|up_4|NZ_LR595691.1_2884164_2884488_-	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|202aa|up_3|NZ_LR595691.1_2884537_2885143_-	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|476aa|up_2|NZ_LR595691.1_2885142_2886570_-	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|303aa|up_1|NZ_LR595691.1_2886571_2887480_-	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|346aa|up_0|NZ_LR595691.1_2887731_2888769_+	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	cas2|98aa|down_0|NZ_LR595691.1_2889524_2889818_-	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	cas1|308aa|down_1|NZ_LR595691.1_2889814_2890738_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|217aa|down_2|NZ_LR595691.1_2890734_2891385_-	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas5|249aa|down_3|NZ_LR595691.1_2891366_2892113_-	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	NA|51aa|down_4|NZ_LR595691.1_2894964_2895117_-	pfam01848, HOK_GEF, Hok/gef family	NA|245aa|down_5|NZ_LR595691.1_2895381_2896116_-	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|571aa|down_6|NZ_LR595691.1_2896189_2897902_-	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit	NA|600aa|down_7|NZ_LR595691.1_2897901_2899701_-	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit	NA|121aa|down_8|NZ_LR595691.1_2900019_2900382_+	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS)	NA|424aa|down_9|NZ_LR595691.1_2900459_2901731_+	PRK10015, PRK10015, oxidoreductase; Provisional
GCF_901733115.1_Escherichia_coli_MAD	NZ_LR595691	Escherichia coli isolate EcMAD1 chromosome EcMAD	4	2911815-2912331	4,2,2	CRISPRCasFinder,CRT,PILER-CR	no		DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	Orphan	CGGTTTATCCCCGCTGGCGCGGGGAACTC,CGGTTTATCCCCGCTGGCGCGGGGAACTC,CGGTTTATCCCCGCTGGCGCGGGGAACTC	29,29,29	0	0	NA	NA	I-E:I-E:I-E	8,8,8	8	Orphan	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	NA,NA|47aa|down_1|NZ_LR595691.1_2913480_2913621_+	NA|424aa|up_9|NZ_LR595691.1_2900459_2901731_+	PRK10015, PRK10015, oxidoreductase; Provisional	NA|87aa|up_8|NZ_LR595691.1_2901721_2901982_+	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|192aa|up_7|NZ_LR595691.1_2901998_2902574_+	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|287aa|up_6|NZ_LR595691.1_2902721_2903582_-	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|260aa|up_5|NZ_LR595691.1_2903578_2904358_-	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|470aa|up_4|NZ_LR595691.1_2904335_2905745_-	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|485aa|up_3|NZ_LR595691.1_2905766_2907221_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|262aa|up_2|NZ_LR595691.1_2907290_2908076_-	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|426aa|up_1|NZ_LR595691.1_2908394_2909672_+	cd06174, MFS, Major Facilitator Superfamily	NA|493aa|up_0|NZ_LR595691.1_2909698_2911177_+	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|224aa|down_0|NZ_LR595691.1_2912670_2913342_-	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|47aa|down_1|NZ_LR595691.1_2913480_2913621_+	NA	NA|291aa|down_2|NZ_LR595691.1_2913634_2914507_+	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|433aa|down_3|NZ_LR595691.1_2914566_2915865_-	PRK00077, eno, enolase; Provisional	NA|546aa|down_4|NZ_LR595691.1_2915952_2917590_-	PRK05380, pyrG, CTP synthetase; Validated	NA|264aa|down_5|NZ_LR595691.1_2917817_2918609_-	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|112aa|down_6|NZ_LR595691.1_2918679_2919015_-	PRK09907, PRK09907, endoribonuclease MazF	NA|83aa|down_7|NZ_LR595691.1_2919014_2919263_-	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|745aa|down_8|NZ_LR595691.1_2919340_2921575_-	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|434aa|down_9|NZ_LR595691.1_2921622_2922924_-	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
GCF_901733115.1_Escherichia_coli_MAD	NZ_LR595691	Escherichia coli isolate EcMAD1 chromosome EcMAD	5	3328981-3329120	5	CRISPRCasFinder	no		DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	Orphan	TGCCTGATGCGACGCTTGCCGCGTCTTATCAGGCCTACAACGACACAAA	49	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,PD-DExK,RT	NA,NA	NA|159aa|up_9|NZ_LR595691.1_3316935_3317412_+	PRK09756, PRK09756, PTS N-acetylgalactosamine transporter subunit IIB	NA|268aa|up_8|NZ_LR595691.1_3317450_3318254_+	PRK09757, PRK09757, PTS N-acetylgalactosamine transporter subunit IIC	NA|264aa|up_7|NZ_LR595691.1_3318243_3319035_+	PRK09855, PRK09855, PTS N-acetylgalactosamine transporter subunit IID	NA|252aa|up_6|NZ_LR595691.1_3319035_3319791_+	PRK09762, PRK09762, galactosamine-6-phosphate isomerase; Provisional	NA|364aa|up_5|NZ_LR595691.1_3323323_3324415_+	pfam00419, Fimbrial, Fimbrial protein	NA|287aa|up_4|NZ_LR595691.1_3324457_3325318_-	PRK14994, PRK14994, SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional	NA|679aa|up_3|NZ_LR595691.1_3325382_3327419_+	COG3107, LppC, Putative lipoprotein [General function prediction only]	NA|132aa|up_2|NZ_LR595691.1_3327376_3327772_+	TIGR00252, UPF0102_protein_HI_1656, TIGR00252 family protein	NA|197aa|up_1|NZ_LR595691.1_3327791_3328382_+	PRK10886, PRK10886, DnaA initiator-associating protein DiaA; Provisional	NA|192aa|up_0|NZ_LR595691.1_3328391_3328967_+	PRK11023, PRK11023, divisome-associated lipoprotein YraP	NA|347aa|down_0|NZ_LR595691.1_3329171_3330212_-	COG0701, COG0701, Predicted permeases [General function prediction only]	NA|212aa|down_1|NZ_LR595691.1_3330284_3330920_-	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs	NA|173aa|down_2|NZ_LR595691.1_3331047_3331566_+	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus	NA|148aa|down_3|NZ_LR595691.1_3331545_3331989_-	PRK03467, PRK03467, hypothetical protein; Provisional	NA|101aa|down_4|NZ_LR595691.1_3332039_3332342_+	PRK00329, PRK00329, GIY-YIG nuclease superfamily protein; Validated	NA|168aa|down_5|NZ_LR595691.1_3332328_3332832_-	COG3153, COG3153, Predicted acetyltransferase [General function prediction only]	NA|175aa|down_6|NZ_LR595691.1_3332825_3333350_-	COG3154, COG3154, Putative lipid carrier protein [Lipid metabolism]	NA|332aa|down_7|NZ_LR595691.1_3333558_3334554_+	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]	NA|293aa|down_8|NZ_LR595691.1_3334562_3335441_+	PRK15447, PRK15447, putative protease; Provisional	NA|336aa|down_9|NZ_LR595691.1_3335646_3336654_+	PRK10508, PRK10508, luciferase-like monooxygenase
