assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	1	406195-406285	1	CRISPRCasFinder	no	DinG	DinG,csa3,DEDDh,cas4,WYL,cas3	Type IV-A	CCGCCGCGCTGCGGCGGGCATCGTCGCCGGGCT	33	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA,NA|153aa|down_3|NZ_CP053068.1_410432_410891_+,NA|96aa|down_4|NZ_CP053068.1_411096_411384_+	NA|336aa|up_9|NZ_CP053068.1_395073_396081_+	PRK13685, PRK13685, hypothetical protein; Provisional	NA|328aa|up_8|NZ_CP053068.1_396099_397083_-	PRK13685, PRK13685, hypothetical protein; Provisional	NA|438aa|up_7|NZ_CP053068.1_397115_398429_-	PLN03142, PLN03142, Probable chromatin-remodeling complex ATPase chain; Provisional	NA|291aa|up_6|NZ_CP053068.1_398454_399327_-	pfam04185, Phosphoesterase, Phosphoesterase family	NA|258aa|up_5|NZ_CP053068.1_399449_400223_+	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed	NA|272aa|up_4|NZ_CP053068.1_401659_402475_-	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional	NA|206aa|up_3|NZ_CP053068.1_402613_403231_+	pfam01083, Cutinase, Cutinase	NA|401aa|up_2|NZ_CP053068.1_403276_404479_+	cd05672, M20_ACY1L2-like, M20 Peptidase aminoacylase 1-like protein 2-like, amidohydrolase subfamily	NA|393aa|up_1|NZ_CP053068.1_404475_405654_+	cd08014, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily	NA|156aa|up_0|NZ_CP053068.1_405676_406144_-	pfam13772, AIG2_2, AIG2-like family	NA|472aa|down_0|NZ_CP053068.1_406297_407713_+	PRK07845, PRK07845, flavoprotein disulfide reductase; Reviewed	NA|585aa|down_1|NZ_CP053068.1_407769_409524_+	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion]	NA|291aa|down_2|NZ_CP053068.1_409520_410393_+	cd02558, PSRA_1, Pseudouridine synthase, a subgroup of the RluA family	NA|153aa|down_3|NZ_CP053068.1_410432_410891_+	NA	NA|96aa|down_4|NZ_CP053068.1_411096_411384_+	NA	NA|379aa|down_5|NZ_CP053068.1_411615_412752_+	pfam00823, PPE, PPE family	NA|118aa|down_6|NZ_CP053068.1_414370_414724_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|306aa|down_7|NZ_CP053068.1_414915_415833_+	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|251aa|down_8|NZ_CP053068.1_415829_416582_-	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]	DinG|1547aa|down_9|NZ_CP053068.1_416584_421225_-	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	2	932492-932572	2	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	GCCGCCGAAGGCGGGTAGCTGGA	23	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA|59aa|up_7|NZ_CP053068.1_925490_925667_-,NA|80aa|up_3|NZ_CP053068.1_928470_928710_-,NA	NA|138aa|up_9|NZ_CP053068.1_924087_924501_+	pfam06150, ChaB, ChaB	NA|280aa|up_8|NZ_CP053068.1_924591_925431_-	cd05355, SDR_c1, classical (c) SDR, subgroup 1	NA|59aa|up_7|NZ_CP053068.1_925490_925667_-	NA	NA|191aa|up_6|NZ_CP053068.1_925976_926549_+	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|323aa|up_5|NZ_CP053068.1_926614_927583_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|232aa|up_4|NZ_CP053068.1_927606_928302_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|80aa|up_3|NZ_CP053068.1_928470_928710_-	NA	NA|266aa|up_2|NZ_CP053068.1_929041_929839_+	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway)	NA|186aa|up_1|NZ_CP053068.1_929854_930412_+	PRK00083, frr, ribosome recycling factor; Reviewed	NA|312aa|up_0|NZ_CP053068.1_930444_931380_+	pfam01148, CTP_transf_1, Cytidylyltransferase family	NA|168aa|down_0|NZ_CP053068.1_932639_933143_+	cd03011, TlpA_like_ScsD_MtbDsbE, TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif	NA|85aa|down_1|NZ_CP053068.1_934002_934257_-	pfam10939, DUF2631, Protein of unknown function (DUF2631)	NA|408aa|down_2|NZ_CP053068.1_934378_935602_+	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional	NA|408aa|down_3|NZ_CP053068.1_935621_936845_+	pfam02163, Peptidase_M50, Peptidase family M50	NA|389aa|down_4|NZ_CP053068.1_936877_938044_+	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA|285aa|down_5|NZ_CP053068.1_938092_938947_+	COG3393, COG3393, Predicted acetyltransferase [General function prediction only]	NA|606aa|down_6|NZ_CP053068.1_939075_940893_+	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|196aa|down_7|NZ_CP053068.1_940938_941526_+	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|286aa|down_8|NZ_CP053068.1_941557_942415_+	PRK12896, PRK12896, methionine aminopeptidase; Reviewed	NA|498aa|down_9|NZ_CP053068.1_942419_943913_+	PRK00784, PRK00784, cobyric acid synthase
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	3	1085964-1086044	3	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	CGCTAATGGCGGTGACCCGCTGCGCC	26	1	1	1085990-1086018	NZ_CP053068.1_351090-351062	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA,NA|176aa|down_5|NZ_CP053068.1_1091334_1091862_-	NA|642aa|up_9|NZ_CP053068.1_1075697_1077623_+	PRK05444, PRK05444, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional	NA|429aa|up_8|NZ_CP053068.1_1077667_1078954_-	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis]	NA|206aa|up_7|NZ_CP053068.1_1078955_1079573_-	pfam11452, DUF3000, Protein of unknown function (DUF3000)	NA|274aa|up_6|NZ_CP053068.1_1079700_1080522_-	PRK07327, PRK07327, enoyl-CoA hydratase/isomerase family protein	NA|358aa|up_5|NZ_CP053068.1_1080569_1081643_+	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated	NA|452aa|up_4|NZ_CP053068.1_1081639_1082995_+	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed	NA|232aa|up_3|NZ_CP053068.1_1083000_1083696_+	COG3253, ywfI, Predicted heme peroxidase involved in anaerobic stress response [General function prediction only]	NA|251aa|up_2|NZ_CP053068.1_1083692_1084445_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|283aa|up_1|NZ_CP053068.1_1084511_1085360_-	pfam18741, MTES_1575, REase_MTES_1575	NA|135aa|up_0|NZ_CP053068.1_1085493_1085898_-	pfam01641, SelR, SelR domain	NA|429aa|down_0|NZ_CP053068.1_1086065_1087352_-	pfam09594, GT87, Glycosyltransferase family 87	NA|520aa|down_1|NZ_CP053068.1_1087380_1088940_-	pfam08386, Abhydrolase_4, TAP-like protein	NA|255aa|down_2|NZ_CP053068.1_1088954_1089719_-	PRK14059, PRK14059, pyrimidine reductase family protein	NA|374aa|down_3|NZ_CP053068.1_1089717_1090839_+	pfam03969, AFG1_ATPase, AFG1-like ATPase	NA|177aa|down_4|NZ_CP053068.1_1090816_1091347_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|176aa|down_5|NZ_CP053068.1_1091334_1091862_-	NA	NA|251aa|down_6|NZ_CP053068.1_1091901_1092654_-	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]	NA|123aa|down_7|NZ_CP053068.1_1092750_1093119_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|115aa|down_8|NZ_CP053068.1_1093318_1093663_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|310aa|down_9|NZ_CP053068.1_1093691_1094621_+	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	4	1115152-1115242	4	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	GACTGCGTCCGACTGCGTCCCACC	24	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA|174aa|up_6|NZ_CP053068.1_1108359_1108881_-,NA|100aa|up_5|NZ_CP053068.1_1109456_1109756_-,NA|155aa|up_4|NZ_CP053068.1_1110215_1110680_-,NA|113aa|up_3|NZ_CP053068.1_1110843_1111182_-,NA|184aa|up_2|NZ_CP053068.1_1112671_1113223_+,NA|97aa|down_0|NZ_CP053068.1_1115653_1115944_+,NA|75aa|down_1|NZ_CP053068.1_1116286_1116511_+,NA|80aa|down_3|NZ_CP053068.1_1117433_1117673_+,NA|145aa|down_4|NZ_CP053068.1_1117665_1118100_+,NA|77aa|down_5|NZ_CP053068.1_1118168_1118399_+,NA|61aa|down_6|NZ_CP053068.1_1118628_1118811_+,NA|173aa|down_8|NZ_CP053068.1_1119464_1119983_-,NA|84aa|down_9|NZ_CP053068.1_1119979_1120231_-	NA|268aa|up_9|NZ_CP053068.1_1105037_1105841_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|405aa|up_8|NZ_CP053068.1_1105844_1107059_+	pfam04909, Amidohydro_2, Amidohydrolase	NA|426aa|up_7|NZ_CP053068.1_1107074_1108352_+	pfam04909, Amidohydro_2, Amidohydrolase	NA|174aa|up_6|NZ_CP053068.1_1108359_1108881_-	NA	NA|100aa|up_5|NZ_CP053068.1_1109456_1109756_-	NA	NA|155aa|up_4|NZ_CP053068.1_1110215_1110680_-	NA	NA|113aa|up_3|NZ_CP053068.1_1110843_1111182_-	NA	NA|184aa|up_2|NZ_CP053068.1_1112671_1113223_+	NA	NA|71aa|up_1|NZ_CP053068.1_1113317_1113530_+	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family	NA|159aa|up_0|NZ_CP053068.1_1113526_1114003_+	pfam10888, DUF2742, Protein of unknown function (DUF2742)	NA|97aa|down_0|NZ_CP053068.1_1115653_1115944_+	NA	NA|75aa|down_1|NZ_CP053068.1_1116286_1116511_+	NA	NA|147aa|down_2|NZ_CP053068.1_1116510_1116951_+	pfam12728, HTH_17, Helix-turn-helix domain	NA|80aa|down_3|NZ_CP053068.1_1117433_1117673_+	NA	NA|145aa|down_4|NZ_CP053068.1_1117665_1118100_+	NA	NA|77aa|down_5|NZ_CP053068.1_1118168_1118399_+	NA	NA|61aa|down_6|NZ_CP053068.1_1118628_1118811_+	NA	NA|103aa|down_7|NZ_CP053068.1_1118789_1119098_-	smart01040, Bro-N, BRO family, N-terminal domain	NA|173aa|down_8|NZ_CP053068.1_1119464_1119983_-	NA	NA|84aa|down_9|NZ_CP053068.1_1119979_1120231_-	NA
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	5	1289780-1289857	5	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	TGGCCGCCGGCGCGGCGGCCGCCA	24	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA|82aa|up_7|NZ_CP053068.1_1280804_1281050_-,NA	NA|373aa|up_9|NZ_CP053068.1_1270589_1271708_+	PRK07865, PRK07865, N-succinyldiaminopimelate aminotransferase; Reviewed	NA|795aa|up_8|NZ_CP053068.1_1271789_1274174_+	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|82aa|up_7|NZ_CP053068.1_1280804_1281050_-	NA	NA|68aa|up_6|NZ_CP053068.1_1281216_1281420_+	pfam09957, VapB_antitoxin, Bacterial antitoxin of type II TA system, VapB	NA|351aa|up_5|NZ_CP053068.1_1281416_1282469_-	pfam00823, PPE, PPE family	NA|396aa|up_4|NZ_CP053068.1_1282543_1283731_-	pfam00823, PPE, PPE family	NA|231aa|up_3|NZ_CP053068.1_1284541_1285234_+	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|420aa|up_2|NZ_CP053068.1_1285230_1286490_+	PRK04149, sat, sulfate adenylyltransferase; Reviewed	NA|111aa|up_1|NZ_CP053068.1_1286486_1286819_+	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional	NA|580aa|up_0|NZ_CP053068.1_1286829_1288569_-	PRK05850, PRK05850, acyl-CoA synthetase; Validated	NA|531aa|down_0|NZ_CP053068.1_1290697_1292290_-	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|547aa|down_1|NZ_CP053068.1_1292374_1294015_+	TIGR01236, D1pyr5carbox1, delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	NA|321aa|down_2|NZ_CP053068.1_1294014_1294977_+	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism]	NA|201aa|down_3|NZ_CP053068.1_1295069_1295672_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|154aa|down_4|NZ_CP053068.1_1296857_1297319_-	cd03455, SAV4209, SAV4209 is a Streptomyces avermitilis protein with a hot dog fold that is similar to those of (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit	NA|374aa|down_5|NZ_CP053068.1_1297315_1298437_-	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|135aa|down_6|NZ_CP053068.1_1298444_1298849_-	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|182aa|down_7|NZ_CP053068.1_1298848_1299394_-	pfam13452, MaoC_dehydrat_N, N-terminal half of MaoC dehydratase	NA|395aa|down_8|NZ_CP053068.1_1299413_1300598_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|399aa|down_9|NZ_CP053068.1_1300602_1301799_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	6	2272658-2272764	6	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	CGTTCGAGTGCCGCTTCGGCGTACGGCGCGCCGCGTTCGGC	41	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA|203aa|up_8|NZ_CP053068.1_2263753_2264362_+,NA|222aa|up_5|NZ_CP053068.1_2266413_2267079_-,NA	NA|407aa|up_9|NZ_CP053068.1_2262312_2263533_-	pfam01548, DEDD_Tnp_IS110, Transposase	NA|203aa|up_8|NZ_CP053068.1_2263753_2264362_+	NA	NA|210aa|up_7|NZ_CP053068.1_2264369_2264999_-	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|408aa|up_6|NZ_CP053068.1_2265092_2266316_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|222aa|up_5|NZ_CP053068.1_2266413_2267079_-	NA	NA|506aa|up_4|NZ_CP053068.1_2267173_2268691_+	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism]	NA|666aa|up_3|NZ_CP053068.1_2268709_2270707_+	pfam02958, EcKinase, Ecdysteroid kinase	NA|165aa|up_2|NZ_CP053068.1_2270703_2271198_+	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism]	NA|130aa|up_1|NZ_CP053068.1_2271278_2271668_+	pfam11903, ParD_like, ParD-like antitoxin of type II bacterial toxin-antitoxin system	NA|193aa|up_0|NZ_CP053068.1_2271698_2272277_+	COG4185, COG4185, Uncharacterized protein conserved in bacteria [Function unknown]	NA|187aa|down_0|NZ_CP053068.1_2273459_2274020_+	cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase)	NA|267aa|down_1|NZ_CP053068.1_2274019_2274820_+	pfam02136, NTF2, Nuclear transport factor 2 (NTF2) domain	NA|117aa|down_2|NZ_CP053068.1_2274833_2275184_-	pfam13564, DoxX_2, DoxX-like family	NA|407aa|down_3|NZ_CP053068.1_2275503_2276724_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|312aa|down_4|NZ_CP053068.1_2276804_2277740_+	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional	NA|443aa|down_5|NZ_CP053068.1_2277805_2279134_+	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|315aa|down_6|NZ_CP053068.1_2279130_2280075_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|281aa|down_7|NZ_CP053068.1_2280061_2280904_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|357aa|down_8|NZ_CP053068.1_2280906_2281977_+	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	NA|323aa|down_9|NZ_CP053068.1_2281984_2282953_+	cd07207, Pat_ExoU_VipD_like, ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	7	2347906-2348004	7	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	CGGTTGCGGCCCGACCCCCAGCGG	24	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA,NA	NA|268aa|up_9|NZ_CP053068.1_2339450_2340254_-	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]	NA|196aa|up_8|NZ_CP053068.1_2340367_2340955_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|295aa|up_7|NZ_CP053068.1_2340975_2341860_-	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase	NA|607aa|up_6|NZ_CP053068.1_2342004_2343825_+	COG1022, FAA1, Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]	NA|218aa|up_5|NZ_CP053068.1_2343848_2344502_-	TIGR03401, Uncharacterized_protein_YFL061W/YNL335W, HD domain protein, cyanamide hydratase family	NA|237aa|up_4|NZ_CP053068.1_2344547_2345258_-	PRK07577, PRK07577, SDR family oxidoreductase	NA|146aa|up_3|NZ_CP053068.1_2345439_2345877_-	pfam00553, CBM_2, Cellulose binding domain	NA|281aa|up_2|NZ_CP053068.1_2346100_2346943_+	pfam12833, HTH_18, Helix-turn-helix domain	NA|134aa|up_1|NZ_CP053068.1_2346896_2347298_+	cd08355, TioX_like, Micromonospora sp	NA|104aa|up_0|NZ_CP053068.1_2347448_2347760_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|152aa|down_0|NZ_CP053068.1_2348146_2348602_+	pfam05988, DUF899, Bacterial protein of unknown function (DUF899)	NA|492aa|down_1|NZ_CP053068.1_2348798_2350274_+	PRK06524, PRK06524, biotin carboxylase-like protein; Validated	NA|392aa|down_2|NZ_CP053068.1_2350270_2351446_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|410aa|down_3|NZ_CP053068.1_2351442_2352672_-	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional	NA|145aa|down_4|NZ_CP053068.1_2352845_2353280_+	pfam00011, HSP20, Hsp20/alpha crystallin family	NA|127aa|down_5|NZ_CP053068.1_2353340_2353721_-	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator	NA|143aa|down_6|NZ_CP053068.1_2353826_2354255_+	pfam00011, HSP20, Hsp20/alpha crystallin family	NA|107aa|down_7|NZ_CP053068.1_2354567_2354888_+	pfam00226, DnaJ, DnaJ domain	NA|506aa|down_8|NZ_CP053068.1_2354941_2356459_-	pfam00668, Condensation, Condensation domain	NA|186aa|down_9|NZ_CP053068.1_2356997_2357555_+	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	8	3027239-3027319	8	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	CCGCCCTACCCCGCTTCGCGGCG	23	0	0	NA	NA	NA	1	1	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA,NA	NA|489aa|up_9|NZ_CP053068.1_3018159_3019626_+	pfam00823, PPE, PPE family	NA|113aa|up_8|NZ_CP053068.1_3019729_3020068_+	TIGR04529, hypothetical_protein, hemophore-related protein, Rv0203/Rv1174c family	NA|155aa|up_7|NZ_CP053068.1_3020101_3020566_-	pfam10756, bPH_6, Bacterial PH domain	NA|161aa|up_6|NZ_CP053068.1_3020562_3021045_-	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional	NA|426aa|up_5|NZ_CP053068.1_3021094_3022372_-	PRK09311, PRK09311, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	NA|200aa|up_4|NZ_CP053068.1_3022493_3023093_-	PRK09289, PRK09289, riboflavin synthase	NA|236aa|up_3|NZ_CP053068.1_3023211_3023919_+	pfam07161, LppX_LprAFG, LppX_LprAFG lipoprotein	NA|519aa|up_2|NZ_CP053068.1_3023915_3025472_+	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|342aa|up_1|NZ_CP053068.1_3025468_3026494_-	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD	NA|236aa|up_0|NZ_CP053068.1_3026490_3027198_-	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated	NA|316aa|down_0|NZ_CP053068.1_3028692_3029640_-	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed	NA|275aa|down_1|NZ_CP053068.1_3029797_3030622_+	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]	NA|162aa|down_2|NZ_CP053068.1_3030627_3031113_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|675aa|down_3|NZ_CP053068.1_3031240_3033265_-	PRK14873, PRK14873, primosomal protein N'	NA|264aa|down_4|NZ_CP053068.1_3033292_3034084_-	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|321aa|down_5|NZ_CP053068.1_3034082_3035045_+	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|497aa|down_6|NZ_CP053068.1_3035090_3036581_+	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|404aa|down_7|NZ_CP053068.1_3036730_3037942_-	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|421aa|down_8|NZ_CP053068.1_3038038_3039301_-	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|109aa|down_9|NZ_CP053068.1_3039322_3039649_-	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit
GCF_013357385.1_ASM1335738v1	NZ_CP053068	Mycobacterium avium subsp. paratuberculosis strain DSM 44135 chromosome, complete genome	9	4650850-4650957	9	CRISPRCasFinder	no		DinG,csa3,DEDDh,cas4,WYL,cas3	Orphan	CGGCCAAGAAGGCACCGGCCAAGA	24	1	2	4650874-4650891|4650874-4650891	NZ_CP053068.1_4027433-4027450|NZ_CP053068.1_2272616-2272599	NA	2	2	Orphan	DinG,csa3,DEDDh,cas4,WYL,cas3	NA,NA	NA|244aa|up_9|NZ_CP053068.1_4642659_4643391_+	TIGR03964, uncharacterized_protein_putative_amidase, mycofactocin system creatininase family protein	NA|473aa|up_8|NZ_CP053068.1_4643387_4644806_+	TIGR03965, glycosyltransferase_Rv0696_family, mycofactocin system glycosyltransferase	NA|480aa|up_7|NZ_CP053068.1_4644815_4646255_+	TIGR03970, Rv0697, dehydrogenase, Rv0697 family	NA|198aa|up_6|NZ_CP053068.1_4646408_4647002_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|102aa|up_5|NZ_CP053068.1_4647353_4647659_+	PRK00596, rpsJ, 30S ribosomal protein S10; Reviewed	NA|218aa|up_4|NZ_CP053068.1_4647673_4648327_+	PRK00001, rplC, 50S ribosomal protein L3; Validated	NA|218aa|up_3|NZ_CP053068.1_4648326_4648980_+	PRK05319, rplD, 50S ribosomal protein L4; Provisional	NA|101aa|up_2|NZ_CP053068.1_4648979_4649282_+	PRK05738, rplW, 50S ribosomal protein L23; Reviewed	NA|281aa|up_1|NZ_CP053068.1_4649304_4650147_+	PRK09374, rplB, 50S ribosomal protein L2; Validated	NA|94aa|up_0|NZ_CP053068.1_4650174_4650456_+	PRK00357, rpsS, 30S ribosomal protein S19; Reviewed	NA|281aa|down_0|NZ_CP053068.1_4650994_4651837_+	PRK00310, rpsC, 30S ribosomal protein S3; Reviewed	NA|139aa|down_1|NZ_CP053068.1_4651840_4652257_+	PRK09203, rplP, 50S ribosomal protein L16; Reviewed	NA|78aa|down_2|NZ_CP053068.1_4652256_4652490_+	PRK00306, PRK00306, 50S ribosomal protein L29; Reviewed	NA|117aa|down_3|NZ_CP053068.1_4652489_4652840_+	PRK05610, rpsQ, 30S ribosomal protein S17; Reviewed	NA|790aa|down_4|NZ_CP053068.1_4652930_4655300_+	cd16025, PAS_like, Bacterial Arylsulfatase of Pseudomonas aeruginosa and related proteins	NA|376aa|down_5|NZ_CP053068.1_4655311_4656439_-	TIGR00975, precursor_PBP-3_PstS-3_Antigen_Ag88	NA|314aa|down_6|NZ_CP053068.1_4656706_4657648_+	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|297aa|down_7|NZ_CP053068.1_4657676_4658567_+	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1	NA|296aa|down_8|NZ_CP053068.1_4658750_4659638_+	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|501aa|down_9|NZ_CP053068.1_4659725_4661228_+	pfam02720, DUF222, Domain of unknown function (DUF222)
