assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	1	59754-60085	1,1	CRISPRCasFinder,CRT	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Type I-E	GTCCTCCCCACGCACATGGGGGTCTGTC,GTCNTCCCCACGCNNNTGGGGGTCTNTC	28,28	0	0	NA	NA	NA:NA	4,5	5	TypeI-E	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|70aa|up_9|NZ_CP047318.1_45631_45841_+,NA|80aa|down_4|NZ_CP047318.1_67213_67453_-,NA|275aa|down_5|NZ_CP047318.1_67735_68560_+,NA|1395aa|down_6|NZ_CP047318.1_68956_73141_-,NA|192aa|down_8|NZ_CP047318.1_78396_78972_+	NA|70aa|up_9|NZ_CP047318.1_45631_45841_+	NA	NA|270aa|up_8|NZ_CP047318.1_46408_47218_-	pfam13401, AAA_22, AAA domain	NA|529aa|up_7|NZ_CP047318.1_47274_48861_-	pfam00665, rve, Integrase core domain	cas6e|237aa|up_6|NZ_CP047318.1_48908_49619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|264aa|up_5|NZ_CP047318.1_49615_50407_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|397aa|up_4|NZ_CP047318.1_50403_51594_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|222aa|up_3|NZ_CP047318.1_51595_52261_-	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional	cas8e|519aa|up_2|NZ_CP047318.1_52324_53881_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cas3|954aa|up_1|NZ_CP047318.1_54546_57408_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|236aa|up_0|NZ_CP047318.1_58814_59522_-	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease	NA|270aa|down_0|NZ_CP047318.1_60267_61076_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|225aa|down_1|NZ_CP047318.1_61651_62326_+	COG1647, COG1647, Esterase/lipase [General function prediction only]	NA|220aa|down_2|NZ_CP047318.1_63484_64144_-	cd18703, PIN_VapC-like, uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily	NA|399aa|down_3|NZ_CP047318.1_65127_66324_-	COG2856, COG2856, Predicted Zn peptidase [Amino acid transport and metabolism]	NA|80aa|down_4|NZ_CP047318.1_67213_67453_-	NA	NA|275aa|down_5|NZ_CP047318.1_67735_68560_+	NA	NA|1395aa|down_6|NZ_CP047318.1_68956_73141_-	NA	NA|1323aa|down_7|NZ_CP047318.1_74274_78243_+	COG2319, COG2319, FOG: WD40 repeat [General function prediction only]	NA|192aa|down_8|NZ_CP047318.1_78396_78972_+	NA	NA|424aa|down_9|NZ_CP047318.1_80906_82178_-	pfam00872, Transposase_mut, Transposase, Mutator family
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	2	60118-60205	2	CRISPRCasFinder	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Type I-E	GTCCTCCCCACGCACATGGGGGTCTGTC	28	0	0	NA	NA	NA	1	1	TypeI-E	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|70aa|up_9|NZ_CP047318.1_45631_45841_+,NA|80aa|down_4|NZ_CP047318.1_67213_67453_-,NA|275aa|down_5|NZ_CP047318.1_67735_68560_+,NA|1395aa|down_6|NZ_CP047318.1_68956_73141_-,NA|192aa|down_8|NZ_CP047318.1_78396_78972_+	NA|70aa|up_9|NZ_CP047318.1_45631_45841_+	NA	NA|270aa|up_8|NZ_CP047318.1_46408_47218_-	pfam13401, AAA_22, AAA domain	NA|529aa|up_7|NZ_CP047318.1_47274_48861_-	pfam00665, rve, Integrase core domain	cas6e|237aa|up_6|NZ_CP047318.1_48908_49619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|264aa|up_5|NZ_CP047318.1_49615_50407_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|397aa|up_4|NZ_CP047318.1_50403_51594_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|222aa|up_3|NZ_CP047318.1_51595_52261_-	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional	cas8e|519aa|up_2|NZ_CP047318.1_52324_53881_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cas3|954aa|up_1|NZ_CP047318.1_54546_57408_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|236aa|up_0|NZ_CP047318.1_58814_59522_-	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease	NA|270aa|down_0|NZ_CP047318.1_60267_61076_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|225aa|down_1|NZ_CP047318.1_61651_62326_+	COG1647, COG1647, Esterase/lipase [General function prediction only]	NA|220aa|down_2|NZ_CP047318.1_63484_64144_-	cd18703, PIN_VapC-like, uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily	NA|399aa|down_3|NZ_CP047318.1_65127_66324_-	COG2856, COG2856, Predicted Zn peptidase [Amino acid transport and metabolism]	NA|80aa|down_4|NZ_CP047318.1_67213_67453_-	NA	NA|275aa|down_5|NZ_CP047318.1_67735_68560_+	NA	NA|1395aa|down_6|NZ_CP047318.1_68956_73141_-	NA	NA|1323aa|down_7|NZ_CP047318.1_74274_78243_+	COG2319, COG2319, FOG: WD40 repeat [General function prediction only]	NA|192aa|down_8|NZ_CP047318.1_78396_78972_+	NA	NA|424aa|down_9|NZ_CP047318.1_80906_82178_-	pfam00872, Transposase_mut, Transposase, Mutator family
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	3	97294-100800	3,2,1,2	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Type I-E	GGGACCATCCCCGCGGGCGCGGGGAGCAC,GGGACCATCCCCGCGGGCGCGGGGAGCAC,GGGACCATCCCCGCGGGCGCGGGGAGCAC,GGGACCATCCCCGCGGGCGCGGGGAGCAC	29,29,29,29	0	0	NA	NA	I-E:I-E:I-E:I-E	57,56,51,51	57	TypeI-E	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|288aa|up_9|NZ_CP047318.1_83538_84402_-,NA|161aa|up_8|NZ_CP047318.1_84603_85086_-,NA|263aa|up_7|NZ_CP047318.1_85261_86050_+,NA|199aa|up_6|NZ_CP047318.1_87111_87708_+,NA|135aa|up_4|NZ_CP047318.1_92661_93066_+,NA|670aa|up_3|NZ_CP047318.1_93028_95038_-,NA|145aa|up_2|NZ_CP047318.1_95634_96069_+,NA	NA|288aa|up_9|NZ_CP047318.1_83538_84402_-	NA	NA|161aa|up_8|NZ_CP047318.1_84603_85086_-	NA	NA|263aa|up_7|NZ_CP047318.1_85261_86050_+	NA	NA|199aa|up_6|NZ_CP047318.1_87111_87708_+	NA	NA|691aa|up_5|NZ_CP047318.1_87704_89777_+	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|135aa|up_4|NZ_CP047318.1_92661_93066_+	NA	NA|670aa|up_3|NZ_CP047318.1_93028_95038_-	NA	NA|145aa|up_2|NZ_CP047318.1_95634_96069_+	NA	NA|141aa|up_1|NZ_CP047318.1_96081_96504_-	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|71aa|up_0|NZ_CP047318.1_96983_97196_+	pfam03457, HA, Helicase associated domain	cas2|117aa|down_0|NZ_CP047318.1_100891_101242_-	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978)	cas1|321aa|down_1|NZ_CP047318.1_101238_102201_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|265aa|down_2|NZ_CP047318.1_102197_102992_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|246aa|down_3|NZ_CP047318.1_102991_103729_-	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|405aa|down_4|NZ_CP047318.1_103725_104940_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|220aa|down_5|NZ_CP047318.1_104985_105645_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|576aa|down_6|NZ_CP047318.1_105641_107369_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cas3|968aa|down_7|NZ_CP047318.1_107361_110265_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|75aa|down_8|NZ_CP047318.1_110959_111184_+	TIGR00710, Bicyclomycin_resistance_protein_homolog, drug resistance transporter, Bcr/CflA subfamily	NA|165aa|down_9|NZ_CP047318.1_111747_112242_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	4	110503-110895	3,4,3	PILER-CR,CRISPRCasFinder,CRT	no	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Type I-E	ACCATCCCCGCGGGTGCGGGGAGC,GCTCCCCGCACCCGCGGGGATGGTCCC,GCTCCCCGCACCCGCGGGGATGGTCCC	24,27,27	0	0	NA	NA	NA:NA:NA	5,6,6	6	TypeI-E	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA,NA|161aa|down_6|NZ_CP047318.1_115330_115813_-	NA|141aa|up_9|NZ_CP047318.1_96081_96504_-	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|71aa|up_8|NZ_CP047318.1_96983_97196_+	pfam03457, HA, Helicase associated domain	cas2|117aa|up_7|NZ_CP047318.1_100891_101242_-	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978)	cas1|321aa|up_6|NZ_CP047318.1_101238_102201_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|265aa|up_5|NZ_CP047318.1_102197_102992_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|246aa|up_4|NZ_CP047318.1_102991_103729_-	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|405aa|up_3|NZ_CP047318.1_103725_104940_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|220aa|up_2|NZ_CP047318.1_104985_105645_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|576aa|up_1|NZ_CP047318.1_105641_107369_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cas3|968aa|up_0|NZ_CP047318.1_107361_110265_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|75aa|down_0|NZ_CP047318.1_110959_111184_+	TIGR00710, Bicyclomycin_resistance_protein_homolog, drug resistance transporter, Bcr/CflA subfamily	NA|165aa|down_1|NZ_CP047318.1_111747_112242_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|209aa|down_2|NZ_CP047318.1_112396_113023_+	cd03025, DsbA_FrnE_like, DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE	NA|269aa|down_3|NZ_CP047318.1_113070_113877_+	cd07739, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|141aa|down_4|NZ_CP047318.1_113881_114304_+	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only]	NA|233aa|down_5|NZ_CP047318.1_114333_115032_+	pfam12697, Abhydrolase_6, Alpha/beta hydrolase family	NA|161aa|down_6|NZ_CP047318.1_115330_115813_-	NA	NA|192aa|down_7|NZ_CP047318.1_118583_119159_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|167aa|down_8|NZ_CP047318.1_119296_119797_-	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain	NA|158aa|down_9|NZ_CP047318.1_120273_120747_-	pfam07080, DUF1348, Protein of unknown function (DUF1348)
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	5	569871-569961	5	CRISPRCasFinder	no	WYL	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Unclear	ACGGAGCATCCCCGCGGGCGCGGGGCCGAC	30	0	0	NA	NA	NA	1	1	Orphan	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|103aa|up_9|NZ_CP047318.1_527692_528001_-,NA|178aa|down_5|NZ_CP047318.1_575038_575572_+	NA|103aa|up_9|NZ_CP047318.1_527692_528001_-	NA	NA|1317aa|up_8|NZ_CP047318.1_528092_532043_-	cd06454, KBL_like, KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I)	NA|374aa|up_7|NZ_CP047318.1_532039_533161_-	COG4335, COG4335, DNA alkylation repair enzyme [DNA replication, recombination, and repair]	NA|3188aa|up_6|NZ_CP047318.1_539598_549162_-	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations	NA|3152aa|up_5|NZ_CP047318.1_549158_558614_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|418aa|up_4|NZ_CP047318.1_560280_561534_-	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion]	NA|401aa|up_3|NZ_CP047318.1_562351_563554_+	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]	NA|204aa|up_2|NZ_CP047318.1_564606_565218_-	pfam02525, Flavodoxin_2, Flavodoxin-like fold	NA|1065aa|up_1|NZ_CP047318.1_565483_568678_-	COG3903, COG3903, Predicted ATPase [General function prediction only]	WYL|246aa|up_0|NZ_CP047318.1_568827_569565_-	COG2378, COG2378, Predicted transcriptional regulator [Transcription]	NA|331aa|down_0|NZ_CP047318.1_570500_571493_+	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional	NA|203aa|down_1|NZ_CP047318.1_571586_572195_+	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit	NA|137aa|down_2|NZ_CP047318.1_572187_572598_+	TIGR02364, dha_pts, dihydroxyacetone kinase, phosphotransfer subunit	NA|228aa|down_3|NZ_CP047318.1_572708_573392_-	pfam07335, Glyco_hydro_75, Fungal chitosanase of glycosyl hydrolase group 75	NA|421aa|down_4|NZ_CP047318.1_573617_574880_+	cd00063, FN3, Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin	NA|178aa|down_5|NZ_CP047318.1_575038_575572_+	NA	NA|672aa|down_6|NZ_CP047318.1_576367_578383_-	cd02930, DCR_FMN, 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain	NA|262aa|down_7|NZ_CP047318.1_578574_579360_-	TIGR03704, PrmC_rel_meth, putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific	NA|249aa|down_8|NZ_CP047318.1_579579_580326_-	pfam08445, FR47, FR47-like protein	NA|202aa|down_9|NZ_CP047318.1_580546_581152_+	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	6	3599744-3599839	6	CRISPRCasFinder	no		cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Orphan	GGCCGGGCAGGCCGGGACCGGTCAGCCCTTG	31	0	0	NA	NA	NA	1	1	Orphan	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA,NA	NA|232aa|up_9|NZ_CP047318.1_3588315_3589011_+	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif	NA|257aa|up_8|NZ_CP047318.1_3589833_3590604_+	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]	NA|846aa|up_7|NZ_CP047318.1_3590735_3593273_+	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]	NA|435aa|up_6|NZ_CP047318.1_3593345_3594650_-	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]	NA|464aa|up_5|NZ_CP047318.1_3595043_3596435_-	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]	NA|91aa|up_4|NZ_CP047318.1_3597032_3597305_+	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system	NA|90aa|up_3|NZ_CP047318.1_3597301_3597571_+	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]	NA|314aa|up_2|NZ_CP047318.1_3597575_3598517_-	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]	NA|202aa|up_1|NZ_CP047318.1_3598513_3599119_-	COG1507, COG1507, Uncharacterized conserved protein [Function unknown]	NA|159aa|up_0|NZ_CP047318.1_3599152_3599629_-	pfam04977, DivIC, Septum formation initiator	NA|244aa|down_0|NZ_CP047318.1_3601561_3602293_-	pfam06737, Transglycosylas, Transglycosylase-like domain	NA|340aa|down_1|NZ_CP047318.1_3602679_3603699_-	pfam06737, Transglycosylas, Transglycosylase-like domain	NA|447aa|down_2|NZ_CP047318.1_3603885_3605226_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|704aa|down_3|NZ_CP047318.1_3605222_3607334_-	sd00010, SLR, Sel1-like repeat	NA|333aa|down_4|NZ_CP047318.1_3607376_3608375_-	PRK12334, PRK12334, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|222aa|down_5|NZ_CP047318.1_3608557_3609223_-	pfam13624, SurA_N_3, SurA N-terminal domain	NA|289aa|down_6|NZ_CP047318.1_3609436_3610303_-	cd06418, GH25_BacA-like, BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues	NA|512aa|down_7|NZ_CP047318.1_3610435_3611971_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|204aa|down_8|NZ_CP047318.1_3611967_3612579_-	pfam09770, PAT1, Topoisomerase II-associated protein PAT1	NA|676aa|down_9|NZ_CP047318.1_3612805_3614833_-	pfam02384, N6_Mtase, N-6 DNA Methylase
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	7	3739551-3739798	7,4	CRISPRCasFinder,PILER-CR	no	WYL	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Unclear	CCAAAACGAAGGTTCGTTCGCGG,CCAAAACGAAGGTTCGTTCGCGG	23,23	0	0	NA	NA	NA:NA	3,2	3	Orphan	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|198aa|up_8|NZ_CP047318.1_3730232_3730826_+,NA|61aa|up_6|NZ_CP047318.1_3731454_3731637_-,NA|253aa|up_2|NZ_CP047318.1_3735954_3736713_+,NA|93aa|up_1|NZ_CP047318.1_3736756_3737035_-,NA	NA|287aa|up_9|NZ_CP047318.1_3729132_3729993_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|198aa|up_8|NZ_CP047318.1_3730232_3730826_+	NA	NA|160aa|up_7|NZ_CP047318.1_3730946_3731426_+	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL	NA|61aa|up_6|NZ_CP047318.1_3731454_3731637_-	NA	NA|428aa|up_5|NZ_CP047318.1_3731839_3733123_+	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA)	NA|368aa|up_4|NZ_CP047318.1_3733179_3734283_+	cd02252, nylC_like, nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC	NA|407aa|up_3|NZ_CP047318.1_3734564_3735785_+	pfam17964, Big_10, Bacterial Ig domain	NA|253aa|up_2|NZ_CP047318.1_3735954_3736713_+	NA	NA|93aa|up_1|NZ_CP047318.1_3736756_3737035_-	NA	NA|702aa|up_0|NZ_CP047318.1_3737216_3739322_-	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional	NA|316aa|down_0|NZ_CP047318.1_3739830_3740778_-	TIGR03828, pfkB, 1-phosphofructokinase	WYL|325aa|down_1|NZ_CP047318.1_3743651_3744626_+	COG2378, COG2378, Predicted transcriptional regulator [Transcription]	NA|333aa|down_2|NZ_CP047318.1_3745437_3746436_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|173aa|down_3|NZ_CP047318.1_3746627_3747146_+	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]	NA|262aa|down_4|NZ_CP047318.1_3747214_3748000_-	cd07363, 45_DOPA_Dioxygenase, The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine	NA|169aa|down_5|NZ_CP047318.1_3748236_3748743_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|513aa|down_6|NZ_CP047318.1_3748924_3750463_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|214aa|down_7|NZ_CP047318.1_3750593_3751235_-	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|426aa|down_8|NZ_CP047318.1_3751649_3752927_+	TIGR03296, hypothetical_protein, M6 family metalloprotease domain	NA|551aa|down_9|NZ_CP047318.1_3753462_3755115_+	TIGR02431, p-hydroxybenzoate_hydroxylase_transcriptional, beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	8	3827255-3827421	4	CRT	no		cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Orphan	GACAACCACGCGCCGGCCCCGCC	23	0	0	NA	NA	NA	3	3	Orphan	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|235aa|up_5|NZ_CP047318.1_3818921_3819626_+,NA|264aa|up_4|NZ_CP047318.1_3819759_3820551_+,NA|227aa|down_5|NZ_CP047318.1_3832560_3833241_+	NA|490aa|up_9|NZ_CP047318.1_3813416_3814886_-	cd07089, ALDH_CddD-AldA-like, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like and related proteins	NA|577aa|up_8|NZ_CP047318.1_3814882_3816613_-	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics	NA|373aa|up_7|NZ_CP047318.1_3816677_3817796_-	COG2141, COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]	NA|252aa|up_6|NZ_CP047318.1_3817931_3818687_-	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|235aa|up_5|NZ_CP047318.1_3818921_3819626_+	NA	NA|264aa|up_4|NZ_CP047318.1_3819759_3820551_+	NA	NA|245aa|up_3|NZ_CP047318.1_3820696_3821431_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|301aa|up_2|NZ_CP047318.1_3821522_3822425_-	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family	NA|417aa|up_1|NZ_CP047318.1_3822502_3823753_-	pfam04909, Amidohydro_2, Amidohydrolase	NA|1019aa|up_0|NZ_CP047318.1_3823950_3827007_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|567aa|down_0|NZ_CP047318.1_3827593_3829294_-	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated	NA|383aa|down_1|NZ_CP047318.1_3829453_3830602_+	PRK07855, PRK07855, lipid-transfer protein; Provisional	NA|139aa|down_2|NZ_CP047318.1_3830637_3831054_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|260aa|down_3|NZ_CP047318.1_3831050_3831830_+	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily	NA|170aa|down_4|NZ_CP047318.1_3831876_3832386_-	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|227aa|down_5|NZ_CP047318.1_3832560_3833241_+	NA	NA|65aa|down_6|NZ_CP047318.1_3833569_3833764_-	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|294aa|down_7|NZ_CP047318.1_3833748_3834630_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|150aa|down_8|NZ_CP047318.1_3834651_3835101_+	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|781aa|down_9|NZ_CP047318.1_3835686_3838029_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	9	4031794-4031889	8	CRISPRCasFinder	no		cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Orphan	TCCGGCTCGCCGTCCGCCTCCGGT	24	0	0	NA	NA	NA	1	1	Orphan	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|229aa|up_9|NZ_CP047318.1_4018932_4019619_-,NA|155aa|up_7|NZ_CP047318.1_4022257_4022722_+,NA|287aa|down_6|NZ_CP047318.1_4041893_4042754_+	NA|229aa|up_9|NZ_CP047318.1_4018932_4019619_-	NA	NA|379aa|up_8|NZ_CP047318.1_4020889_4022026_+	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	NA|155aa|up_7|NZ_CP047318.1_4022257_4022722_+	NA	NA|244aa|up_6|NZ_CP047318.1_4022922_4023654_+	cd04181, NTP_transferase, NTP_transferases catalyze the transfer of nucleotides onto phosphosugars	NA|561aa|up_5|NZ_CP047318.1_4023861_4025544_-	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|314aa|up_4|NZ_CP047318.1_4025648_4026590_-	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis]	NA|473aa|up_3|NZ_CP047318.1_4026707_4028126_-	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated	NA|169aa|up_2|NZ_CP047318.1_4028483_4028990_-	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|255aa|up_1|NZ_CP047318.1_4028979_4029744_-	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|161aa|up_0|NZ_CP047318.1_4030024_4030507_-	COG1329, COG1329, Transcriptional regulators, similar to M	NA|227aa|down_0|NZ_CP047318.1_4032035_4032716_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|419aa|down_1|NZ_CP047318.1_4032712_4033969_-	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR	NA|230aa|down_2|NZ_CP047318.1_4034496_4035186_+	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU	NA|290aa|down_3|NZ_CP047318.1_4035963_4036833_+	COG3393, COG3393, Predicted acetyltransferase [General function prediction only]	NA|254aa|down_4|NZ_CP047318.1_4036998_4037760_-	PRK14120, gpmA, phosphoglyceromutase; Provisional	NA|447aa|down_5|NZ_CP047318.1_4040093_4041434_-	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase	NA|287aa|down_6|NZ_CP047318.1_4041893_4042754_+	NA	NA|374aa|down_7|NZ_CP047318.1_4043051_4044173_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|473aa|down_8|NZ_CP047318.1_4044752_4046171_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|115aa|down_9|NZ_CP047318.1_4046321_4046666_-	pfam10724, DUF2516, Protein of unknown function (DUF2516)
GCF_009857135.1_ASM985713v1	NZ_CP047318	Streptomyces sp. HM190 chromosome, complete genome	10	4083389-4083475	9	CRISPRCasFinder	no		cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	Orphan	GCTCCACGCGCGTGCGCAAGCGCGTC	26	0	0	NA	NA	NA	1	1	Orphan	cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas2,cas1,csa3,WYL,DEDDh,cas4,Cas9_archaeal,DinG	NA|67aa|up_4|NZ_CP047318.1_4077263_4077464_+,NA|329aa|down_2|NZ_CP047318.1_4086091_4087078_+,NA|279aa|down_3|NZ_CP047318.1_4087074_4087911_+,NA|275aa|down_7|NZ_CP047318.1_4092397_4093222_+	NA|85aa|up_9|NZ_CP047318.1_4072226_4072481_-	cd17040, Ubl_MoaD_like, ubiquitin-like (Ubl) domain found in a group of small sulfide carrier proteins	NA|237aa|up_8|NZ_CP047318.1_4072511_4073222_-	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|260aa|up_7|NZ_CP047318.1_4073779_4074559_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|341aa|up_6|NZ_CP047318.1_4074665_4075688_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|400aa|up_5|NZ_CP047318.1_4075871_4077071_+	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|67aa|up_4|NZ_CP047318.1_4077263_4077464_+	NA	NA|245aa|up_3|NZ_CP047318.1_4077603_4078338_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|488aa|up_2|NZ_CP047318.1_4078334_4079798_+	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|297aa|up_1|NZ_CP047318.1_4080121_4081012_+	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown]	NA|601aa|up_0|NZ_CP047318.1_4081162_4082965_-	cd07412, MPP_YhcR_N, Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain	NA|310aa|down_0|NZ_CP047318.1_4083626_4084556_+	TIGR03448, mycothiol_MshD, mycothiol synthase	NA|132aa|down_1|NZ_CP047318.1_4084692_4085088_+	COG1725, COG1725, Predicted transcriptional regulators [Transcription]	NA|329aa|down_2|NZ_CP047318.1_4086091_4087078_+	NA	NA|279aa|down_3|NZ_CP047318.1_4087074_4087911_+	NA	NA|744aa|down_4|NZ_CP047318.1_4088346_4090578_+	PRK05443, PRK05443, polyphosphate kinase; Provisional	NA|374aa|down_5|NZ_CP047318.1_4090537_4091659_+	smart00880, CHAD, The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family	NA|138aa|down_6|NZ_CP047318.1_4091655_4092069_+	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily	NA|275aa|down_7|NZ_CP047318.1_4092397_4093222_+	NA	NA|122aa|down_8|NZ_CP047318.1_4093668_4094034_-	pfam02583, Trns_repr_metal, Metal-sensitive transcriptional repressor	NA|207aa|down_9|NZ_CP047318.1_4094222_4094843_+	COG1392, COG1392, Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]
