assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	1	29310-29635	1	CRISPRCasFinder	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ACAGGATGGCAAGAAATAGATGGTAA	26	0	0	NA	NA	NA	5	5	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|458aa|up_7|NZ_CP046327.1_12112_13486_+,NA|664aa|up_3|NZ_CP046327.1_24143_26135_+,NA|107aa|up_2|NZ_CP046327.1_26124_26445_+,NA	NA|235aa|up_9|NZ_CP046327.1_9906_10611_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|441aa|up_8|NZ_CP046327.1_10603_11926_+	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|458aa|up_7|NZ_CP046327.1_12112_13486_+	NA	NA|313aa|up_6|NZ_CP046327.1_13858_14797_-	cd10948, CE4_BsPdaA_like, Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs	NA|226aa|up_5|NZ_CP046327.1_20057_20735_-	cd05826, Sortase_B, Sortase domain found in class B sortases	NA|848aa|up_4|NZ_CP046327.1_21478_24022_+	PTZ00121, PTZ00121, MAEBL; Provisional	NA|664aa|up_3|NZ_CP046327.1_24143_26135_+	NA	NA|107aa|up_2|NZ_CP046327.1_26124_26445_+	NA	NA|292aa|up_1|NZ_CP046327.1_26636_27512_+	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]	NA|338aa|up_0|NZ_CP046327.1_27536_28550_+	PLN02240, PLN02240, UDP-glucose 4-epimerase	NA|280aa|down_0|NZ_CP046327.1_30774_31614_+	cd01027, TOPRIM_RNase_M5_like, TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea	NA|294aa|down_1|NZ_CP046327.1_31821_32703_-	cd08434, PBP2_GltC_like, The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold	NA|283aa|down_2|NZ_CP046327.1_33115_33964_+	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|641aa|down_3|NZ_CP046327.1_34042_35965_+	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2	NA|288aa|down_4|NZ_CP046327.1_36046_36910_+	PRK12548, PRK12548, shikimate dehydrogenase	NA|406aa|down_5|NZ_CP046327.1_37109_38327_+	cd17396, MFS_YdiM_like, Inner membrane transport protein YdiM and similar proteins of the Major Facilitator Superfamily of transporters	NA|623aa|down_6|NZ_CP046327.1_38559_40428_+	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p	NA|455aa|down_7|NZ_CP046327.1_40605_41970_-	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases	NA|448aa|down_8|NZ_CP046327.1_42116_43460_-	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]	NA|218aa|down_9|NZ_CP046327.1_43963_44617_+	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	2	801637-802320	1,2,1	PILER-CR,CRISPRCasFinder,CRT	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	GTTTTATATTAACTATATGGAATGTAAAG,GTTTTATATTAACTATATGGAATGTAAAG,GTTTTATATTAACTATATGGAATGTAAA	29,29,28	0	0	NA	NA	I-A:I-A:I-A	8,9,10	10	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|567aa|up_9|NZ_CP046327.1_790529_792230_+,NA|216aa|up_8|NZ_CP046327.1_792369_793017_+,NA|80aa|up_7|NZ_CP046327.1_793187_793427_+,NA|98aa|down_0|NZ_CP046327.1_802421_802715_+,NA|58aa|down_1|NZ_CP046327.1_802871_803045_-,NA|43aa|down_4|NZ_CP046327.1_804315_804444_-	NA|567aa|up_9|NZ_CP046327.1_790529_792230_+	NA	NA|216aa|up_8|NZ_CP046327.1_792369_793017_+	NA	NA|80aa|up_7|NZ_CP046327.1_793187_793427_+	NA	NA|398aa|up_6|NZ_CP046327.1_793377_794571_+	PRK06635, PRK06635, aspartate kinase; Reviewed	NA|431aa|up_5|NZ_CP046327.1_794588_795881_+	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase	NA|220aa|up_4|NZ_CP046327.1_796097_796757_+	pfam03154, Atrophin-1, Atrophin-1 family	NA|362aa|up_3|NZ_CP046327.1_796911_797997_-	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|239aa|up_2|NZ_CP046327.1_798187_798904_+	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]	NA|193aa|up_1|NZ_CP046327.1_798961_799540_+	pfam06962, rRNA_methylase, Putative rRNA methylase	NA|291aa|up_0|NZ_CP046327.1_799933_800806_+	COG1737, RpiR, Transcriptional regulators [Transcription]	NA|98aa|down_0|NZ_CP046327.1_802421_802715_+	NA	NA|58aa|down_1|NZ_CP046327.1_802871_803045_-	NA	NA|72aa|down_2|NZ_CP046327.1_803484_803700_-	COG3655, COG3655, Predicted transcriptional regulator [Transcription]	NA|156aa|down_3|NZ_CP046327.1_803710_804178_-	pfam11188, DUF2975, Protein of unknown function (DUF2975)	NA|43aa|down_4|NZ_CP046327.1_804315_804444_-	NA	NA|233aa|down_5|NZ_CP046327.1_805199_805898_-	TIGR03502, lipase_Pla1_cef, extracellular lipase, Pla-1/cef family	NA|186aa|down_6|NZ_CP046327.1_806155_806713_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|158aa|down_7|NZ_CP046327.1_807081_807555_-	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain	NA|255aa|down_8|NZ_CP046327.1_807857_808622_+	pfam14268, YoaP, YoaP-like	NA|345aa|down_9|NZ_CP046327.1_809311_810346_+	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	3	1151624-1152578	3,2,2	CRISPRCasFinder,CRT,PILER-CR	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ATTTACATACCACATAGTTAATATAAAAC,ATTTACATACCACATAGTTAATATAAAAC,GTTTTATATTAACTATGTGGTATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	14,14,13	14	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|258aa|up_8|NZ_CP046327.1_1141086_1141860_-,NA|341aa|up_6|NZ_CP046327.1_1142766_1143789_-,NA|59aa|up_5|NZ_CP046327.1_1144363_1144540_+,NA|96aa|up_0|NZ_CP046327.1_1150927_1151215_-,NA|80aa|down_0|NZ_CP046327.1_1152773_1153013_-	NA|242aa|up_9|NZ_CP046327.1_1140249_1140975_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|258aa|up_8|NZ_CP046327.1_1141086_1141860_-	NA	NA|296aa|up_7|NZ_CP046327.1_1141865_1142753_-	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component	NA|341aa|up_6|NZ_CP046327.1_1142766_1143789_-	NA	NA|59aa|up_5|NZ_CP046327.1_1144363_1144540_+	NA	NA|195aa|up_4|NZ_CP046327.1_1145640_1146225_-	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates	NA|615aa|up_3|NZ_CP046327.1_1146546_1148391_-	cd08579, GDPD_memb_like, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases	NA|321aa|up_2|NZ_CP046327.1_1148685_1149648_-	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase	NA|184aa|up_1|NZ_CP046327.1_1149838_1150390_+	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain	NA|96aa|up_0|NZ_CP046327.1_1150927_1151215_-	NA	NA|80aa|down_0|NZ_CP046327.1_1152773_1153013_-	NA	NA|424aa|down_1|NZ_CP046327.1_1153224_1154496_+	cd01303, GDEase, Guanine deaminase (GDEase)	NA|252aa|down_2|NZ_CP046327.1_1155134_1155890_-	pfam12395, DUF3658, Protein of unknown function	NA|106aa|down_3|NZ_CP046327.1_1156228_1156546_+	pfam06865, DUF1255, Protein of unknown function (DUF1255)	NA|786aa|down_4|NZ_CP046327.1_1156631_1158989_-	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7	NA|486aa|down_5|NZ_CP046327.1_1159411_1160869_-	PRK04366, PRK04366, aminomethyl-transferring glycine dehydrogenase subunit GcvPB	NA|825aa|down_6|NZ_CP046327.1_1160868_1163343_-	PRK00451, PRK00451, aminomethyl-transferring glycine dehydrogenase subunit GcvPA	NA|577aa|down_7|NZ_CP046327.1_1164743_1166474_-	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion]	NA|329aa|down_8|NZ_CP046327.1_1166957_1167944_+	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase	NA|266aa|down_9|NZ_CP046327.1_1168253_1169051_+	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	4	1289856-1290146	4,3,3	CRISPRCasFinder,CRT,PILER-CR	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	GATTTACATTCCATATAGTTAATATAAAAC,ATTTACATTCCANATAGTTAATATAAAAC,GTTTTATATTAACTATATGGAATGTAAAT	30,29,29	0	0	NA	NA	I-A:I-A:I-A	4,4,3	4	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA,NA|45aa|down_0|NZ_CP046327.1_1290411_1290546_-,NA|63aa|down_2|NZ_CP046327.1_1291583_1291772_-,NA|54aa|down_3|NZ_CP046327.1_1293108_1293270_-,NA|276aa|down_6|NZ_CP046327.1_1294122_1294950_-,NA|59aa|down_9|NZ_CP046327.1_1296806_1296983_-	NA|342aa|up_9|NZ_CP046327.1_1279877_1280903_-	pfam12571, DUF3751, Phage tail-collar fibre protein	NA|206aa|up_8|NZ_CP046327.1_1280914_1281532_-	pfam10076, DUF2313, Uncharacterized protein conserved in bacteria (DUF2313)	NA|350aa|up_7|NZ_CP046327.1_1281524_1282574_-	pfam04865, Baseplate_J, Baseplate J-like protein	NA|140aa|up_6|NZ_CP046327.1_1282574_1282994_-	pfam10934, DUF2634, Protein of unknown function (DUF2634)	NA|87aa|up_5|NZ_CP046327.1_1282998_1283259_-	pfam10844, DUF2577, Protein of unknown function (DUF2577)	NA|631aa|up_4|NZ_CP046327.1_1283272_1285165_-	pfam00877, NLPC_P60, NlpC/P60 family	NA|230aa|up_3|NZ_CP046327.1_1285157_1285847_-	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional	NA|791aa|up_2|NZ_CP046327.1_1285863_1288236_-	TIGR02675, Mu-like_prophage_FluMu_protein_gp42, tape measure domain	NA|256aa|up_1|NZ_CP046327.1_1288301_1289069_-	pfam14471, DUF4428, Domain of unknown function (DUF4428)	NA|176aa|up_0|NZ_CP046327.1_1289206_1289734_-	pfam11611, DUF4352, Domain of unknown function (DUF4352)	NA|45aa|down_0|NZ_CP046327.1_1290411_1290546_-	NA	NA|289aa|down_1|NZ_CP046327.1_1290598_1291465_-	smart01040, Bro-N, BRO family, N-terminal domain	NA|63aa|down_2|NZ_CP046327.1_1291583_1291772_-	NA	NA|54aa|down_3|NZ_CP046327.1_1293108_1293270_-	NA	NA|65aa|down_4|NZ_CP046327.1_1293416_1293611_-	TIGR02247, Hypothetical_protein_K09H11	NA|147aa|down_5|NZ_CP046327.1_1293610_1294051_-	pfam08890, Phage_TAC_5, Phage XkdN-like tail assembly chaperone protein, TAC	NA|276aa|down_6|NZ_CP046327.1_1294122_1294950_-	NA	NA|157aa|down_7|NZ_CP046327.1_1295008_1295479_-	pfam09393, DUF2001, Phage tail tube protein	NA|437aa|down_8|NZ_CP046327.1_1295495_1296806_-	pfam04984, Phage_sheath_1, Phage tail sheath protein subtilisin-like domain	NA|59aa|down_9|NZ_CP046327.1_1296806_1296983_-	NA
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	5	1292011-1292367	5,4,4	CRISPRCasFinder,CRT,PILER-CR	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ATTTACATTCCATATAGTTAATCTAAAAC,ATTTACATTCCATATAGTTAATCTAAAAC,GTTTTAGATTAACTATATGGAATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	5,5,4	5	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|45aa|up_2|NZ_CP046327.1_1290411_1290546_-,NA|63aa|up_0|NZ_CP046327.1_1291583_1291772_-,NA|54aa|down_0|NZ_CP046327.1_1293108_1293270_-,NA|276aa|down_3|NZ_CP046327.1_1294122_1294950_-,NA|59aa|down_6|NZ_CP046327.1_1296806_1296983_-,NA|146aa|down_7|NZ_CP046327.1_1296975_1297413_-,NA|269aa|down_8|NZ_CP046327.1_1297761_1298568_-	NA|140aa|up_9|NZ_CP046327.1_1282574_1282994_-	pfam10934, DUF2634, Protein of unknown function (DUF2634)	NA|87aa|up_8|NZ_CP046327.1_1282998_1283259_-	pfam10844, DUF2577, Protein of unknown function (DUF2577)	NA|631aa|up_7|NZ_CP046327.1_1283272_1285165_-	pfam00877, NLPC_P60, NlpC/P60 family	NA|230aa|up_6|NZ_CP046327.1_1285157_1285847_-	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional	NA|791aa|up_5|NZ_CP046327.1_1285863_1288236_-	TIGR02675, Mu-like_prophage_FluMu_protein_gp42, tape measure domain	NA|256aa|up_4|NZ_CP046327.1_1288301_1289069_-	pfam14471, DUF4428, Domain of unknown function (DUF4428)	NA|176aa|up_3|NZ_CP046327.1_1289206_1289734_-	pfam11611, DUF4352, Domain of unknown function (DUF4352)	NA|45aa|up_2|NZ_CP046327.1_1290411_1290546_-	NA	NA|289aa|up_1|NZ_CP046327.1_1290598_1291465_-	smart01040, Bro-N, BRO family, N-terminal domain	NA|63aa|up_0|NZ_CP046327.1_1291583_1291772_-	NA	NA|54aa|down_0|NZ_CP046327.1_1293108_1293270_-	NA	NA|65aa|down_1|NZ_CP046327.1_1293416_1293611_-	TIGR02247, Hypothetical_protein_K09H11	NA|147aa|down_2|NZ_CP046327.1_1293610_1294051_-	pfam08890, Phage_TAC_5, Phage XkdN-like tail assembly chaperone protein, TAC	NA|276aa|down_3|NZ_CP046327.1_1294122_1294950_-	NA	NA|157aa|down_4|NZ_CP046327.1_1295008_1295479_-	pfam09393, DUF2001, Phage tail tube protein	NA|437aa|down_5|NZ_CP046327.1_1295495_1296806_-	pfam04984, Phage_sheath_1, Phage tail sheath protein subtilisin-like domain	NA|59aa|down_6|NZ_CP046327.1_1296806_1296983_-	NA	NA|146aa|down_7|NZ_CP046327.1_1296975_1297413_-	NA	NA|269aa|down_8|NZ_CP046327.1_1297761_1298568_-	NA	NA|97aa|down_9|NZ_CP046327.1_1298677_1298968_-	pfam04883, HK97-gp10_like, Bacteriophage HK97-gp10, putative tail-component
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	6	1384751-1385044	6,5,5	CRISPRCasFinder,CRT,PILER-CR	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ATTTACATTCCATATAGTTAATATAAAAC,ATTTACATTCCATATAGTTAATATAAAAC,GTTTTATATTAACTATATGGAATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	4,4,3	4	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|323aa|up_5|NZ_CP046327.1_1378859_1379828_-,NA|91aa|up_0|NZ_CP046327.1_1384310_1384583_+,NA|61aa|down_4|NZ_CP046327.1_1391453_1391636_+,NA|190aa|down_7|NZ_CP046327.1_1394585_1395155_-,NA|50aa|down_9|NZ_CP046327.1_1396069_1396219_-	NA|182aa|up_9|NZ_CP046327.1_1374135_1374681_-	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain	NA|305aa|up_8|NZ_CP046327.1_1374903_1375818_-	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]	NA|294aa|up_7|NZ_CP046327.1_1376233_1377115_+	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins	NA|403aa|up_6|NZ_CP046327.1_1377175_1378384_-	PRK13354, PRK13354, tyrosyl-tRNA synthetase; Provisional	NA|323aa|up_5|NZ_CP046327.1_1378859_1379828_-	NA	NA|147aa|up_4|NZ_CP046327.1_1380000_1380441_+	COG2153, ElaA, Predicted acyltransferase [General function prediction only]	NA|76aa|up_3|NZ_CP046327.1_1380767_1380995_+	pfam04023, FeoA, FeoA domain	NA|707aa|up_2|NZ_CP046327.1_1381020_1383141_+	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism]	NA|273aa|up_1|NZ_CP046327.1_1383273_1384092_-	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator	NA|91aa|up_0|NZ_CP046327.1_1384310_1384583_+	NA	NA|698aa|down_0|NZ_CP046327.1_1385704_1387798_-	cd01948, EAL, EAL domain	NA|308aa|down_1|NZ_CP046327.1_1388450_1389374_+	pfam10728, DUF2520, Domain of unknown function (DUF2520)	NA|276aa|down_2|NZ_CP046327.1_1389348_1390176_+	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed	NA|283aa|down_3|NZ_CP046327.1_1390194_1391043_+	PRK00380, panC, pantoate--beta-alanine ligase; Reviewed	NA|61aa|down_4|NZ_CP046327.1_1391453_1391636_+	NA	NA|305aa|down_5|NZ_CP046327.1_1392467_1393382_+	pfam11155, DUF2935, Domain of unknown function (DUF2935)	NA|216aa|down_6|NZ_CP046327.1_1393771_1394419_+	pfam02589, LUD_dom, LUD domain	NA|190aa|down_7|NZ_CP046327.1_1394585_1395155_-	NA	NA|300aa|down_8|NZ_CP046327.1_1395159_1396059_-	TIGR02163, Ferredoxin-type_protein_NapH_homolog, ferredoxin-type protein, NapH/MauN family	NA|50aa|down_9|NZ_CP046327.1_1396069_1396219_-	NA
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	7	1495663-1496415	7,6,6	CRISPRCasFinder,CRT,PILER-CR	no	DinG	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Type IV-A	ATTTACATACCACTTAGTTAATATAAAAC,ATTTACATACCACTTAGTTAATATAAAAC,GTTTTATATTAACTAAGTGGTATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	11,11,10	11	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|45aa|up_9|NZ_CP046327.1_1485165_1485300_-,NA|59aa|up_5|NZ_CP046327.1_1487926_1488103_+,NA|80aa|up_4|NZ_CP046327.1_1488290_1488530_-,NA|183aa|down_4|NZ_CP046327.1_1501220_1501769_+	NA|45aa|up_9|NZ_CP046327.1_1485165_1485300_-	NA	NA|122aa|up_8|NZ_CP046327.1_1485530_1485896_+	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|185aa|up_7|NZ_CP046327.1_1485973_1486528_+	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases	NA|225aa|up_6|NZ_CP046327.1_1486747_1487422_+	COG1285, SapB, Uncharacterized membrane protein [Function unknown]	NA|59aa|up_5|NZ_CP046327.1_1487926_1488103_+	NA	NA|80aa|up_4|NZ_CP046327.1_1488290_1488530_-	NA	NA|270aa|up_3|NZ_CP046327.1_1488674_1489484_-	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators	NA|745aa|up_2|NZ_CP046327.1_1490253_1492488_+	cd01948, EAL, EAL domain	NA|282aa|up_1|NZ_CP046327.1_1492518_1493364_+	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|578aa|up_0|NZ_CP046327.1_1493603_1495337_+	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|131aa|down_0|NZ_CP046327.1_1496945_1497338_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|452aa|down_1|NZ_CP046327.1_1498432_1499788_+	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA	NA|223aa|down_2|NZ_CP046327.1_1499905_1500574_-	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily	NA|143aa|down_3|NZ_CP046327.1_1500640_1501069_-	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ	NA|183aa|down_4|NZ_CP046327.1_1501220_1501769_+	NA	NA|312aa|down_5|NZ_CP046327.1_1501888_1502824_+	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only]	NA|315aa|down_6|NZ_CP046327.1_1503094_1504039_-	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter	NA|477aa|down_7|NZ_CP046327.1_1504354_1505785_+	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]	NA|195aa|down_8|NZ_CP046327.1_1505984_1506569_+	pfam00882, Zn_dep_PLPC, Zinc dependent phospholipase C	NA|260aa|down_9|NZ_CP046327.1_1506672_1507452_-	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	8	1704804-1705761	7,8,7	PILER-CR,CRISPRCasFinder,CRT	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	GTTTTATATTAACTAAGTGGTATGTAAAG,CTTTACATACCACTTAGTTAATATAAAAC,CTTTACATACCACTTAGTTAATATAAAAC	29,29,29	0	0	NA	NA	I-A:I-A:I-A	14,14,14	14	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|190aa|up_9|NZ_CP046327.1_1698309_1698879_+,NA|106aa|up_8|NZ_CP046327.1_1699170_1699488_+,NA|40aa|up_7|NZ_CP046327.1_1699548_1699668_+,NA|72aa|up_6|NZ_CP046327.1_1700473_1700689_-,NA|115aa|up_5|NZ_CP046327.1_1700871_1701216_-,NA|128aa|up_4|NZ_CP046327.1_1701342_1701726_+,NA|38aa|up_3|NZ_CP046327.1_1702511_1702625_-,NA|84aa|up_2|NZ_CP046327.1_1702934_1703186_-,NA|34aa|up_1|NZ_CP046327.1_1703305_1703407_-,NA|52aa|up_0|NZ_CP046327.1_1703431_1703587_-,NA|75aa|down_2|NZ_CP046327.1_1708175_1708400_-	NA|190aa|up_9|NZ_CP046327.1_1698309_1698879_+	NA	NA|106aa|up_8|NZ_CP046327.1_1699170_1699488_+	NA	NA|40aa|up_7|NZ_CP046327.1_1699548_1699668_+	NA	NA|72aa|up_6|NZ_CP046327.1_1700473_1700689_-	NA	NA|115aa|up_5|NZ_CP046327.1_1700871_1701216_-	NA	NA|128aa|up_4|NZ_CP046327.1_1701342_1701726_+	NA	NA|38aa|up_3|NZ_CP046327.1_1702511_1702625_-	NA	NA|84aa|up_2|NZ_CP046327.1_1702934_1703186_-	NA	NA|34aa|up_1|NZ_CP046327.1_1703305_1703407_-	NA	NA|52aa|up_0|NZ_CP046327.1_1703431_1703587_-	NA	NA|311aa|down_0|NZ_CP046327.1_1706668_1707601_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|224aa|down_1|NZ_CP046327.1_1707561_1708233_-	pfam13518, HTH_28, Helix-turn-helix domain	NA|75aa|down_2|NZ_CP046327.1_1708175_1708400_-	NA	NA|476aa|down_3|NZ_CP046327.1_1708542_1709970_-	NF033435, S-layer_Clost, S-layer protein SlpA	NA|274aa|down_4|NZ_CP046327.1_1710160_1710982_+	sd00006, TPR, Tetratricopeptide repeat	NA|506aa|down_5|NZ_CP046327.1_1711106_1712624_+	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain	NA|555aa|down_6|NZ_CP046327.1_1713027_1714692_-	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|416aa|down_7|NZ_CP046327.1_1714763_1716011_-	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]	NA|225aa|down_8|NZ_CP046327.1_1715997_1716672_-	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only]	NA|360aa|down_9|NZ_CP046327.1_1716843_1717923_-	pfam02618, YceG, YceG-like family
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	9	2283787-2283869	9	CRISPRCasFinder	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	TGCATAATACCATCTTCACTAAA	23	0	0	NA	NA	NA	1	1	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|101aa|up_7|NZ_CP046327.1_2271401_2271704_+,NA|61aa|up_2|NZ_CP046327.1_2282427_2282610_-,NA|44aa|up_1|NZ_CP046327.1_2282698_2282830_-,NA|43aa|down_8|NZ_CP046327.1_2300380_2300509_+,NA|397aa|down_9|NZ_CP046327.1_2301411_2302602_-	NA|254aa|up_9|NZ_CP046327.1_2269371_2270133_+	pfam12730, ABC2_membrane_4, ABC-2 family transporter protein	NA|246aa|up_8|NZ_CP046327.1_2270144_2270882_+	COG4200, COG4200, Uncharacterized protein conserved in bacteria [Function unknown]	NA|101aa|up_7|NZ_CP046327.1_2271401_2271704_+	NA	NA|90aa|up_6|NZ_CP046327.1_2271915_2272185_+	pfam12675, DUF3795, Protein of unknown function (DUF3795)	NA|82aa|up_5|NZ_CP046327.1_2272401_2272647_-	pfam11731, Cdd1, Pathogenicity locus	NA|187aa|up_4|NZ_CP046327.1_2273183_2273744_+	pfam12569, NARP1, NMDA receptor-regulated protein 1	NA|2711aa|up_3|NZ_CP046327.1_2274078_2282211_-	pfam12920, TcdA_TcdB_pore, TcdA/TcdB pore forming domain	NA|61aa|up_2|NZ_CP046327.1_2282427_2282610_-	NA	NA|44aa|up_1|NZ_CP046327.1_2282698_2282830_-	NA	NA|167aa|up_0|NZ_CP046327.1_2282938_2283439_-	TIGR01593, Uncharacterized_protein_CPE0383, toxin secretion/phage lysis holin	NA|185aa|down_0|NZ_CP046327.1_2290991_2291546_-	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family	NA|127aa|down_1|NZ_CP046327.1_2292454_2292835_-	pfam03965, Penicillinase_R, Penicillinase repressor	NA|398aa|down_2|NZ_CP046327.1_2293041_2294235_-	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]	NA|407aa|down_3|NZ_CP046327.1_2294297_2295518_-	cd03682, ClC_sycA_like, ClC sycA-like chloride channel proteins	NA|245aa|down_4|NZ_CP046327.1_2296695_2297430_-	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain	NA|213aa|down_5|NZ_CP046327.1_2298403_2299042_-	pfam13346, ABC2_membrane_5, ABC-2 family transporter protein	NA|286aa|down_6|NZ_CP046327.1_2299044_2299902_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|125aa|down_7|NZ_CP046327.1_2299903_2300278_-	COG1725, COG1725, Predicted transcriptional regulators [Transcription]	NA|43aa|down_8|NZ_CP046327.1_2300380_2300509_+	NA	NA|397aa|down_9|NZ_CP046327.1_2301411_2302602_-	NA
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	10	2861364-2861443	10	CRISPRCasFinder	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	TTATAATATTATCCACATTATAAACA	26	0	0	NA	NA	NA	1	1	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|226aa|up_5|NZ_CP046327.1_2843850_2844528_-,NA|40aa|up_2|NZ_CP046327.1_2846708_2846828_-,NA	NA|186aa|up_9|NZ_CP046327.1_2841174_2841732_-	pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase	NA|251aa|up_8|NZ_CP046327.1_2841732_2842485_-	cd03375, TPP_OGFOR, Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor	NA|360aa|up_7|NZ_CP046327.1_2842484_2843564_-	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated	NA|72aa|up_6|NZ_CP046327.1_2843592_2843808_-	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion]	NA|226aa|up_5|NZ_CP046327.1_2843850_2844528_-	NA	NA|360aa|up_4|NZ_CP046327.1_2844517_2845597_-	PRK03011, PRK03011, butyrate kinase; Provisional	NA|301aa|up_3|NZ_CP046327.1_2845618_2846521_-	PRK05805, PRK05805, phosphate butyryltransferase; Validated	NA|40aa|up_2|NZ_CP046327.1_2846708_2846828_-	NA	NA|394aa|up_1|NZ_CP046327.1_2846824_2848006_-	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown]	NA|280aa|up_0|NZ_CP046327.1_2848002_2848842_-	COG1624, COG1624, Uncharacterized conserved protein [Function unknown]	NA|180aa|down_0|NZ_CP046327.1_2861923_2862463_-	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein	NA|784aa|down_1|NZ_CP046327.1_2862484_2864836_-	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional	NA|395aa|down_2|NZ_CP046327.1_2865208_2866393_+	PRK05764, PRK05764, aspartate aminotransferase; Provisional	NA|235aa|down_3|NZ_CP046327.1_2878761_2879466_-	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD	NA|131aa|down_4|NZ_CP046327.1_2879972_2880365_-	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed	NA|144aa|down_5|NZ_CP046327.1_2880393_2880825_-	PRK09216, rplM, 50S ribosomal protein L13; Reviewed	NA|244aa|down_6|NZ_CP046327.1_2880944_2881676_-	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA	NA|268aa|down_7|NZ_CP046327.1_2881707_2882511_-	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]	NA|289aa|down_8|NZ_CP046327.1_2882504_2883371_-	PRK13637, cbiO, energy-coupling factor transporter ATPase	NA|278aa|down_9|NZ_CP046327.1_2883358_2884192_-	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	11	3570189-3571311	8	CRT	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	CAANNGGAGCAACNGGAGCAANNGG	25	6	13	3570358-3570377|3570358-3570377|3570403-3570422|3570493-3570512|3570493-3570512|3570628-3570647|3571132-3571151|3571132-3571151|3571222-3571241|3571222-3571241|3571222-3571241|3571222-3571241|3571222-3571241	NZ_CP046327.1_3452174-3452193|NZ_CP046327.1_3452354-3452373|NZ_CP046327.1_1444661-1444642|NZ_CP046327.1_48581-48562|NZ_CP046327.1_1444661-1444642|NZ_CP046327.1_3452216-3452235|NZ_CP046327.1_3452372-3452391|NZ_CP046327.1_3453182-3453201|NZ_CP046327.1_3452225-3452244|NZ_CP046327.1_3452363-3452382|NZ_CP046327.1_3452138-3452157|NZ_CP046327.1_3452147-3452166|NZ_CP046327.1_3453029-3453048	NA	22	22	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA,NA	NA|253aa|up_9|NZ_CP046327.1_3559303_3560062_+	TIGR04482, D_pro_red_PrdD, proline reductase cluster protein PrdD	NA|156aa|up_8|NZ_CP046327.1_3560076_3560544_+	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein	NA|161aa|up_7|NZ_CP046327.1_3560561_3561044_+	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein	NA|336aa|up_6|NZ_CP046327.1_3561063_3562071_+	PRK13969, PRK13969, proline racemase; Provisional	NA|294aa|up_5|NZ_CP046327.1_3562190_3563072_+	pfam01925, TauE, Sulfite exporter TauE/SafE	NA|212aa|up_4|NZ_CP046327.1_3563739_3564375_+	PRK05813, PRK05813, single-stranded DNA-binding protein; Provisional	NA|190aa|up_3|NZ_CP046327.1_3564558_3565128_+	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]	NA|592aa|up_2|NZ_CP046327.1_3565339_3567115_+	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]	NA|428aa|up_1|NZ_CP046327.1_3567563_3568847_+	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|180aa|up_0|NZ_CP046327.1_3569174_3569714_+	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]	NA|252aa|down_0|NZ_CP046327.1_3572313_3573069_-	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional	NA|330aa|down_1|NZ_CP046327.1_3573509_3574499_+	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily	NA|239aa|down_2|NZ_CP046327.1_3574769_3575486_-	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA|250aa|down_3|NZ_CP046327.1_3575709_3576459_-	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional	NA|296aa|down_4|NZ_CP046327.1_3576525_3577413_-	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional	NA|334aa|down_5|NZ_CP046327.1_3577529_3578531_-	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional	NA|294aa|down_6|NZ_CP046327.1_3578955_3579837_-	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional	NA|398aa|down_7|NZ_CP046327.1_3580159_3581353_+	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form	NA|373aa|down_8|NZ_CP046327.1_3581558_3582677_+	cd05670, M20_Acy1_YkuR-like, M20 Peptidase aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins	NA|85aa|down_9|NZ_CP046327.1_3582798_3583053_+	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	12	3688414-3689036	8,11,9	PILER-CR,CRISPRCasFinder,CRT	no	cas5,cas6,cas7,cas3,WYL	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Unclear	ATTTATAACTAACTTAGTGTAATTTAAAC,GTTTAAATTACACTAAGTTAGTTATAAAT,GTTTAAATTACACTAAGTTAGTTATAAAT	29,29,29	0	0	NA	NA	NA:NA:NA	8,9,9	9	Unclear	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|105aa|up_9|NZ_CP046327.1_3677675_3677990_+,NA|250aa|up_8|NZ_CP046327.1_3678005_3678755_+,NA|91aa|up_6|NZ_CP046327.1_3680351_3680624_+,NA|389aa|up_2|NZ_CP046327.1_3683907_3685074_+,NA|57aa|down_0|NZ_CP046327.1_3691510_3691681_+,NA|76aa|down_5|NZ_CP046327.1_3695653_3695881_-,NA|540aa|down_7|NZ_CP046327.1_3697462_3699082_+,NA|243aa|down_8|NZ_CP046327.1_3699099_3699828_+	NA|105aa|up_9|NZ_CP046327.1_3677675_3677990_+	NA	NA|250aa|up_8|NZ_CP046327.1_3678005_3678755_+	NA	NA|445aa|up_7|NZ_CP046327.1_3678767_3680102_+	TIGR00665, DnaB, replicative DNA helicase	NA|91aa|up_6|NZ_CP046327.1_3680351_3680624_+	NA	NA|376aa|up_5|NZ_CP046327.1_3680896_3682024_+	COG3183, COG3183, Predicted restriction endonuclease [Defense mechanisms]	cas5|216aa|up_4|NZ_CP046327.1_3682503_3683151_+	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP	cas6|255aa|up_3|NZ_CP046327.1_3683141_3683906_+	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|389aa|up_2|NZ_CP046327.1_3683907_3685074_+	NA	cas7|357aa|up_1|NZ_CP046327.1_3685094_3686165_+	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP	cas3|662aa|up_0|NZ_CP046327.1_3686175_3688161_+	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3	NA|57aa|down_0|NZ_CP046327.1_3691510_3691681_+	NA	NA|405aa|down_1|NZ_CP046327.1_3692214_3693429_+	pfam08867, FRG, FRG domain	NA|431aa|down_2|NZ_CP046327.1_3693428_3694721_+	pfam03235, DUF262, Protein of unknown function DUF262	NA|62aa|down_3|NZ_CP046327.1_3694947_3695133_-	pfam13333, rve_2, Integrase core domain	NA|130aa|down_4|NZ_CP046327.1_3695162_3695552_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|76aa|down_5|NZ_CP046327.1_3695653_3695881_-	NA	NA|337aa|down_6|NZ_CP046327.1_3696452_3697463_+	pfam09983, DUF2220, Uncharacterized protein conserved in bacteria C-term(DUF2220)	NA|540aa|down_7|NZ_CP046327.1_3697462_3699082_+	NA	NA|243aa|down_8|NZ_CP046327.1_3699099_3699828_+	NA	NA|1452aa|down_9|NZ_CP046327.1_3699814_3704170_+	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	13	3934424-3936170	9,12,10	PILER-CR,CRISPRCasFinder,CRT	no	WYL,cas6,cas8b2,cas7,cas5,cas3,cas4,cas1,cas2	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Unclear	GTTTTATATTAACTAAGTGGTATGTAAAT,GTTTTATATTAACTAAGTGGTATGTAAAT,GTTTTATATTAACTAAGTGGTATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	23,26,24	26	Unclear	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA,NA|260aa|down_1|NZ_CP046327.1_3937114_3937894_-,NA|67aa|down_7|NZ_CP046327.1_3943077_3943278_-	NA|639aa|up_9|NZ_CP046327.1_3922660_3924577_+	pfam02687, FtsX, FtsX-like permease family	WYL|306aa|up_8|NZ_CP046327.1_3924855_3925773_+	pfam13280, WYL, WYL domain	cas6|246aa|up_7|NZ_CP046327.1_3925850_3926588_+	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6	cas8b2|626aa|up_6|NZ_CP046327.1_3926593_3928471_+	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1	cas7|305aa|up_5|NZ_CP046327.1_3928472_3929387_+	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7	cas5|234aa|up_4|NZ_CP046327.1_3929388_3930090_+	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas3|774aa|up_3|NZ_CP046327.1_3930100_3932422_+	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3	cas4|173aa|up_2|NZ_CP046327.1_3932469_3932988_+	pfam01930, Cas_Cas4, Domain of unknown function DUF83	cas1|327aa|up_1|NZ_CP046327.1_3932990_3933971_+	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP	cas2|89aa|up_0|NZ_CP046327.1_3933973_3934240_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|143aa|down_0|NZ_CP046327.1_3936230_3936659_+	PRK10562, PRK10562, putative acetyltransferase; Provisional	NA|260aa|down_1|NZ_CP046327.1_3937114_3937894_-	NA	NA|182aa|down_2|NZ_CP046327.1_3938217_3938763_+	pfam02632, BioY, BioY family	NA|379aa|down_3|NZ_CP046327.1_3938794_3939931_+	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine	NA|464aa|down_4|NZ_CP046327.1_3939934_3941326_+	cd17633, AFD_YhfT-like, fatty acid-CoA ligase VraA	NA|292aa|down_5|NZ_CP046327.1_3941401_3942277_+	PRK08306, PRK08306, dipicolinate synthase subunit DpsA	NA|197aa|down_6|NZ_CP046327.1_3942279_3942870_+	PRK08305, spoVFB, dipicolinate synthase subunit B; Reviewed	NA|67aa|down_7|NZ_CP046327.1_3943077_3943278_-	NA	NA|885aa|down_8|NZ_CP046327.1_3943781_3946436_+	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional	NA|740aa|down_9|NZ_CP046327.1_3946711_3948931_+	cd01948, EAL, EAL domain
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	14	4152093-4152183	13	CRISPRCasFinder	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ATATGTTTAGAAGCTGTAAAAAAA	24	0	0	NA	NA	NA	1	1	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|222aa|up_0|NZ_CP046327.1_4150822_4151488_-,NA	NA|157aa|up_9|NZ_CP046327.1_4139833_4140304_-	pfam14270, DUF4358, Domain of unknown function (DUF4358)	NA|215aa|up_8|NZ_CP046327.1_4140442_4141087_+	cd00475, Cis_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases	NA|302aa|up_7|NZ_CP046327.1_4141129_4142035_+	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3	NA|516aa|up_6|NZ_CP046327.1_4142349_4143897_+	cd01948, EAL, EAL domain	NA|133aa|up_5|NZ_CP046327.1_4143899_4144298_+	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|578aa|up_4|NZ_CP046327.1_4144337_4146071_+	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX	NA|404aa|up_3|NZ_CP046327.1_4146302_4147514_+	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli	NA|87aa|up_2|NZ_CP046327.1_4147705_4147966_+	pfam00381, PTS-HPr, PTS HPr component phosphorylation site	NA|571aa|up_1|NZ_CP046327.1_4148318_4150031_+	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]	NA|222aa|up_0|NZ_CP046327.1_4150822_4151488_-	NA	NA|193aa|down_0|NZ_CP046327.1_4153629_4154208_+	pfam04647, AgrB, Accessory gene regulator B	NA|49aa|down_1|NZ_CP046327.1_4154237_4154384_+	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|460aa|down_2|NZ_CP046327.1_4154688_4156068_+	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase	NA|166aa|down_3|NZ_CP046327.1_4156096_4156594_+	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|555aa|down_4|NZ_CP046327.1_4156891_4158556_+	COG0661, AarF, Predicted unusual protein kinase [General function prediction only]	NA|817aa|down_5|NZ_CP046327.1_4158568_4161019_+	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ	NA|171aa|down_6|NZ_CP046327.1_4161031_4161544_+	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional	NA|736aa|down_7|NZ_CP046327.1_4161617_4163825_+	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|150aa|down_8|NZ_CP046327.1_4163849_4164299_+	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional	NA|205aa|down_9|NZ_CP046327.1_4164313_4164928_+	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	15	4152387-4152675	14	CRISPRCasFinder	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ATATGTTTAGAAGCTGTAAAAAAA	24	0	0	NA	NA	NA	4	4	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|222aa|up_0|NZ_CP046327.1_4150822_4151488_-,NA	NA|157aa|up_9|NZ_CP046327.1_4139833_4140304_-	pfam14270, DUF4358, Domain of unknown function (DUF4358)	NA|215aa|up_8|NZ_CP046327.1_4140442_4141087_+	cd00475, Cis_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases	NA|302aa|up_7|NZ_CP046327.1_4141129_4142035_+	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3	NA|516aa|up_6|NZ_CP046327.1_4142349_4143897_+	cd01948, EAL, EAL domain	NA|133aa|up_5|NZ_CP046327.1_4143899_4144298_+	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|578aa|up_4|NZ_CP046327.1_4144337_4146071_+	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX	NA|404aa|up_3|NZ_CP046327.1_4146302_4147514_+	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli	NA|87aa|up_2|NZ_CP046327.1_4147705_4147966_+	pfam00381, PTS-HPr, PTS HPr component phosphorylation site	NA|571aa|up_1|NZ_CP046327.1_4148318_4150031_+	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]	NA|222aa|up_0|NZ_CP046327.1_4150822_4151488_-	NA	NA|193aa|down_0|NZ_CP046327.1_4153629_4154208_+	pfam04647, AgrB, Accessory gene regulator B	NA|49aa|down_1|NZ_CP046327.1_4154237_4154384_+	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|460aa|down_2|NZ_CP046327.1_4154688_4156068_+	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase	NA|166aa|down_3|NZ_CP046327.1_4156096_4156594_+	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|555aa|down_4|NZ_CP046327.1_4156891_4158556_+	COG0661, AarF, Predicted unusual protein kinase [General function prediction only]	NA|817aa|down_5|NZ_CP046327.1_4158568_4161019_+	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ	NA|171aa|down_6|NZ_CP046327.1_4161031_4161544_+	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional	NA|736aa|down_7|NZ_CP046327.1_4161617_4163825_+	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|150aa|down_8|NZ_CP046327.1_4163849_4164299_+	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional	NA|205aa|down_9|NZ_CP046327.1_4164313_4164928_+	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
GCF_009730495.1_ASM973049v1	NZ_CP046327	Clostridioides difficile strain FDAARGOS_723 chromosome, complete genome	16	4152783-4152956	15	CRISPRCasFinder	no		cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	Orphan	ATATGTTTAGAAGCTGTAAAAAAA	24	0	0	NA	NA	NA	2	2	Orphan	cas14j,cas3,cas6,cas7,cas5,DEDDh,WYL,cas14k,csa3,DinG,cas8b2,cas4,cas1,cas2	NA|222aa|up_0|NZ_CP046327.1_4150822_4151488_-,NA	NA|157aa|up_9|NZ_CP046327.1_4139833_4140304_-	pfam14270, DUF4358, Domain of unknown function (DUF4358)	NA|215aa|up_8|NZ_CP046327.1_4140442_4141087_+	cd00475, Cis_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases	NA|302aa|up_7|NZ_CP046327.1_4141129_4142035_+	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3	NA|516aa|up_6|NZ_CP046327.1_4142349_4143897_+	cd01948, EAL, EAL domain	NA|133aa|up_5|NZ_CP046327.1_4143899_4144298_+	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|578aa|up_4|NZ_CP046327.1_4144337_4146071_+	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX	NA|404aa|up_3|NZ_CP046327.1_4146302_4147514_+	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli	NA|87aa|up_2|NZ_CP046327.1_4147705_4147966_+	pfam00381, PTS-HPr, PTS HPr component phosphorylation site	NA|571aa|up_1|NZ_CP046327.1_4148318_4150031_+	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]	NA|222aa|up_0|NZ_CP046327.1_4150822_4151488_-	NA	NA|193aa|down_0|NZ_CP046327.1_4153629_4154208_+	pfam04647, AgrB, Accessory gene regulator B	NA|49aa|down_1|NZ_CP046327.1_4154237_4154384_+	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|460aa|down_2|NZ_CP046327.1_4154688_4156068_+	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase	NA|166aa|down_3|NZ_CP046327.1_4156096_4156594_+	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|555aa|down_4|NZ_CP046327.1_4156891_4158556_+	COG0661, AarF, Predicted unusual protein kinase [General function prediction only]	NA|817aa|down_5|NZ_CP046327.1_4158568_4161019_+	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ	NA|171aa|down_6|NZ_CP046327.1_4161031_4161544_+	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional	NA|736aa|down_7|NZ_CP046327.1_4161617_4163825_+	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|150aa|down_8|NZ_CP046327.1_4163849_4164299_+	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional	NA|205aa|down_9|NZ_CP046327.1_4164313_4164928_+	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
