assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	1	208447-208737	1	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	GACACAGCCGCGCCAGGCCCGGAC	24	0	0	NA	NA	NA	4	4	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA,NA	NA|380aa|up_9|NZ_CP023694.1_198342_199482_+	pfam01636, APH, Phosphotransferase enzyme family	NA|166aa|up_8|NZ_CP023694.1_199554_200052_-	PRK15480, PRK15480, glucose-1-phosphate thymidylyltransferase RfbA; Provisional	NA|210aa|up_7|NZ_CP023694.1_200110_200740_-	COG5516, COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only]	NA|301aa|up_6|NZ_CP023694.1_200750_201653_-	pfam00582, Usp, Universal stress protein family	NA|81aa|up_5|NZ_CP023694.1_201836_202079_-	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|389aa|up_4|NZ_CP023694.1_202161_203328_-	PRK08313, PRK08313, thiolase domain-containing protein	NA|355aa|up_3|NZ_CP023694.1_203324_204389_-	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|314aa|up_2|NZ_CP023694.1_204385_205327_-	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|267aa|up_1|NZ_CP023694.1_205345_206146_-	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|540aa|up_0|NZ_CP023694.1_206322_207942_+	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|238aa|down_0|NZ_CP023694.1_210487_211201_-	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|281aa|down_1|NZ_CP023694.1_211263_212106_-	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|509aa|down_2|NZ_CP023694.1_212173_213700_-	PRK08316, PRK08316, acyl-CoA synthetase; Validated	NA|813aa|down_3|NZ_CP023694.1_213855_216294_+	pfam01804, Penicil_amidase, Penicillin amidase	NA|422aa|down_4|NZ_CP023694.1_216343_217609_-	COG2311, COG2311, Predicted membrane protein [Function unknown]	NA|518aa|down_5|NZ_CP023694.1_217721_219275_-	PRK08276, PRK08276, long-chain-fatty-acid--CoA ligase; Validated	NA|370aa|down_6|NZ_CP023694.1_219271_220381_-	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]	NA|590aa|down_7|NZ_CP023694.1_220506_222276_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|64aa|down_8|NZ_CP023694.1_222286_222478_-	pfam11387, DUF2795, Protein of unknown function (DUF2795)	NA|538aa|down_9|NZ_CP023694.1_222574_224188_-	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	2	1484870-1484967	2	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	CCAATTTCACCAATCTCGTCACC	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|70aa|up_3|NZ_CP023694.1_1482693_1482903_+,NA|75aa|up_2|NZ_CP023694.1_1482899_1483124_+,NA|117aa|up_1|NZ_CP023694.1_1483249_1483600_+,NA|85aa|down_0|NZ_CP023694.1_1485063_1485318_+,NA|56aa|down_1|NZ_CP023694.1_1485314_1485482_+,NA|79aa|down_2|NZ_CP023694.1_1485663_1485900_+,NA|50aa|down_3|NZ_CP023694.1_1485987_1486137_+,NA|89aa|down_4|NZ_CP023694.1_1486133_1486400_+,NA|95aa|down_7|NZ_CP023694.1_1493078_1493363_-,NA|63aa|down_8|NZ_CP023694.1_1493470_1493659_-,NA|109aa|down_9|NZ_CP023694.1_1494025_1494352_-	NA|338aa|up_9|NZ_CP023694.1_1473901_1474915_+	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|332aa|up_8|NZ_CP023694.1_1476657_1477653_-	PRK06148, PRK06148, hypothetical protein; Provisional	NA|450aa|up_7|NZ_CP023694.1_1477760_1479110_-	COG0160, GabT, 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]	NA|389aa|up_6|NZ_CP023694.1_1479286_1480453_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|399aa|up_5|NZ_CP023694.1_1480765_1481962_-	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|203aa|up_4|NZ_CP023694.1_1481954_1482563_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|70aa|up_3|NZ_CP023694.1_1482693_1482903_+	NA	NA|75aa|up_2|NZ_CP023694.1_1482899_1483124_+	NA	NA|117aa|up_1|NZ_CP023694.1_1483249_1483600_+	NA	NA|392aa|up_0|NZ_CP023694.1_1483596_1484772_+	pfam13481, AAA_25, AAA domain	NA|85aa|down_0|NZ_CP023694.1_1485063_1485318_+	NA	NA|56aa|down_1|NZ_CP023694.1_1485314_1485482_+	NA	NA|79aa|down_2|NZ_CP023694.1_1485663_1485900_+	NA	NA|50aa|down_3|NZ_CP023694.1_1485987_1486137_+	NA	NA|89aa|down_4|NZ_CP023694.1_1486133_1486400_+	NA	NA|403aa|down_5|NZ_CP023694.1_1486692_1487901_+	pfam05065, Phage_capsid, Phage capsid family	NA|1110aa|down_6|NZ_CP023694.1_1487913_1491243_+	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains	NA|95aa|down_7|NZ_CP023694.1_1493078_1493363_-	NA	NA|63aa|down_8|NZ_CP023694.1_1493470_1493659_-	NA	NA|109aa|down_9|NZ_CP023694.1_1494025_1494352_-	NA
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	3	2027312-2027421	3	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	GGTTGTTCGCGCAGTTCCCCGCGCCCCTG	29	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA,NA|317aa|down_3|NZ_CP023694.1_2030437_2031388_-,NA|300aa|down_4|NZ_CP023694.1_2031754_2032654_+	NA|78aa|up_9|NZ_CP023694.1_2014661_2014895_-	pfam03777, DUF320, Small secreted domain (DUF320)	NA|442aa|up_8|NZ_CP023694.1_2015069_2016395_-	PRK07906, PRK07906, hypothetical protein; Provisional	NA|1289aa|up_7|NZ_CP023694.1_2016966_2020833_+	TIGR02353, NON-RIBOSOMAL_PEPTIDE_SYNTHETASE, non-ribosomal peptide synthetase terminal domain of unknown function	NA|448aa|up_6|NZ_CP023694.1_2020901_2022245_+	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain	NA|128aa|up_5|NZ_CP023694.1_2022249_2022633_+	COG3012, COG3012, Uncharacterized protein conserved in bacteria [Function unknown]	NA|234aa|up_4|NZ_CP023694.1_2022639_2023341_-	COG2186, FadR, Transcriptional regulators [Transcription]	NA|173aa|up_3|NZ_CP023694.1_2023478_2023997_+	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism]	NA|466aa|up_2|NZ_CP023694.1_2024048_2025446_+	pfam02447, GntP_permease, GntP family permease	NA|255aa|up_1|NZ_CP023694.1_2025459_2026224_+	PRK07523, PRK07523, gluconate 5-dehydrogenase; Provisional	NA|344aa|up_0|NZ_CP023694.1_2026244_2027276_+	cd08232, idonate-5-DH, L-idonate 5-dehydrogenase	NA|205aa|down_0|NZ_CP023694.1_2027429_2028044_-	COG2864, FdnI, Cytochrome b subunit of formate dehydrogenase [Energy production and conversion]	NA|242aa|down_1|NZ_CP023694.1_2028027_2028753_-	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains	NA|512aa|down_2|NZ_CP023694.1_2028864_2030400_-	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|317aa|down_3|NZ_CP023694.1_2030437_2031388_-	NA	NA|300aa|down_4|NZ_CP023694.1_2031754_2032654_+	NA	NA|179aa|down_5|NZ_CP023694.1_2032681_2033218_+	PRK15393, PRK15393, NUDIX hydrolase YfcD; Provisional	NA|131aa|down_6|NZ_CP023694.1_2033249_2033642_+	COG2149, COG2149, Predicted membrane protein [Function unknown]	NA|115aa|down_7|NZ_CP023694.1_2033629_2033974_+	pfam02656, DUF202, Domain of unknown function (DUF202)	NA|315aa|down_8|NZ_CP023694.1_2034110_2035055_-	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases	NA|341aa|down_9|NZ_CP023694.1_2035253_2036276_+	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	4	2263464-2263578	4	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	CATCGGGGCGCGGGACTTCACGCCGGTGCGGTGA	34	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA,NA|336aa|down_7|NZ_CP023694.1_2269887_2270895_+	NA|352aa|up_9|NZ_CP023694.1_2252877_2253933_+	PRK07908, PRK07908, threonine-phosphate decarboxylase	NA|364aa|up_8|NZ_CP023694.1_2254271_2255363_-	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site	NA|264aa|up_7|NZ_CP023694.1_2255384_2256176_-	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|279aa|up_6|NZ_CP023694.1_2256172_2257009_-	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|282aa|up_5|NZ_CP023694.1_2257005_2257851_-	cd13624, PBP2_Arg_Lys_His, Substrate binding domain of the arginine-, lysine-, histidine-binding protein ArtJ; the type 2 periplasmic binding protein fold	NA|370aa|up_4|NZ_CP023694.1_2258059_2259169_+	COG0075, COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]	NA|176aa|up_3|NZ_CP023694.1_2259444_2259972_+	pfam04978, DUF664, Protein of unknown function (DUF664)	NA|169aa|up_2|NZ_CP023694.1_2260310_2260817_+	TIGR02406, L-24-diaminobutyric_acid_acetyltransferase, diaminobutyrate acetyltransferase	NA|424aa|up_1|NZ_CP023694.1_2260869_2262141_+	PRK09264, PRK09264, diaminobutyrate--2-oxoglutarate transaminase	NA|133aa|up_0|NZ_CP023694.1_2262183_2262582_+	PRK13290, ectC, L-ectoine synthase; Reviewed	NA|363aa|down_0|NZ_CP023694.1_2263707_2264796_-	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]	NA|238aa|down_1|NZ_CP023694.1_2264855_2265569_-	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif	NA|155aa|down_2|NZ_CP023694.1_2265645_2266110_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|203aa|down_3|NZ_CP023694.1_2266186_2266795_-	pfam07081, DUF1349, Protein of unknown function (DUF1349)	NA|510aa|down_4|NZ_CP023694.1_2266887_2268417_-	cd07129, ALDH_KGSADH, Alpha-Ketoglutaric Semialdehyde Dehydrogenase	NA|258aa|down_5|NZ_CP023694.1_2268549_2269323_+	COG1414, IclR, Transcriptional regulator [Transcription]	NA|157aa|down_6|NZ_CP023694.1_2269326_2269797_+	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|336aa|down_7|NZ_CP023694.1_2269887_2270895_+	NA	NA|429aa|down_8|NZ_CP023694.1_2270891_2272178_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|221aa|down_9|NZ_CP023694.1_2272174_2272837_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	5	2347742-2347853	5	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	CCGCCGTCGGTGGCACTTCCGCGCTCCTTCCCC	33	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|473aa|up_9|NZ_CP023694.1_2338496_2339915_-,NA|234aa|up_4|NZ_CP023694.1_2344164_2344866_-,NA|50aa|up_3|NZ_CP023694.1_2344862_2345012_-,NA|77aa|up_1|NZ_CP023694.1_2346165_2346396_-,NA	NA|473aa|up_9|NZ_CP023694.1_2338496_2339915_-	NA	NA|610aa|up_8|NZ_CP023694.1_2340221_2342051_+	COG2374, COG2374, Predicted extracellular nuclease [General function prediction only]	NA|229aa|up_7|NZ_CP023694.1_2342109_2342796_-	pfam03992, ABM, Antibiotic biosynthesis monooxygenase	NA|132aa|up_6|NZ_CP023694.1_2343134_2343530_-	pfam12277, DUF3618, Protein of unknown function (DUF3618)	NA|140aa|up_5|NZ_CP023694.1_2343526_2343946_-	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|234aa|up_4|NZ_CP023694.1_2344164_2344866_-	NA	NA|50aa|up_3|NZ_CP023694.1_2344862_2345012_-	NA	NA|295aa|up_2|NZ_CP023694.1_2345207_2346092_+	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional	NA|77aa|up_1|NZ_CP023694.1_2346165_2346396_-	NA	NA|330aa|up_0|NZ_CP023694.1_2346609_2347599_-	TIGR03535, DapD_actino, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA|183aa|down_0|NZ_CP023694.1_2347875_2348424_-	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown]	NA|107aa|down_1|NZ_CP023694.1_2348423_2348744_-	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]	NA|280aa|down_2|NZ_CP023694.1_2348916_2349756_+	pfam05270, AbfB, Alpha-L-arabinofuranosidase B (ABFB) domain	NA|111aa|down_3|NZ_CP023694.1_2349812_2350145_-	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]	NA|157aa|down_4|NZ_CP023694.1_2350141_2350612_-	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family	NA|419aa|down_5|NZ_CP023694.1_2350627_2351884_-	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily	NA|255aa|down_6|NZ_CP023694.1_2351880_2352645_-	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]	NA|106aa|down_7|NZ_CP023694.1_2352652_2352970_-	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO)	NA|395aa|down_8|NZ_CP023694.1_2352966_2354151_-	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]	NA|474aa|down_9|NZ_CP023694.1_2354208_2355630_-	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	6	2493808-2494064	1	CRT	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	CGTCCGCGTGGTTCNCNCCCGCACCC	26	1	1	2493975-2493992	NZ_CP023694.1_5180185-5180202	NA	5	5	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|263aa|up_5|NZ_CP023694.1_2485665_2486454_+,NA|296aa|down_5|NZ_CP023694.1_2499371_2500259_+	NA|604aa|up_9|NZ_CP023694.1_2481274_2483086_+	PRK11301, livM, leucine/isoleucine/valine transporter permease subunit; Provisional	NA|289aa|up_8|NZ_CP023694.1_2483091_2483958_+	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system	NA|239aa|up_7|NZ_CP023694.1_2483954_2484671_+	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]	NA|219aa|up_6|NZ_CP023694.1_2484736_2485393_-	COG3707, AmiR, Response regulator with putative antiterminator output domain [Signal transduction mechanisms]	NA|263aa|up_5|NZ_CP023694.1_2485665_2486454_+	NA	NA|479aa|up_4|NZ_CP023694.1_2486461_2487898_-	PRK06247, PRK06247, pyruvate kinase; Provisional	NA|240aa|up_3|NZ_CP023694.1_2488062_2488782_-	pfam04402, SIMPL, Protein of unknown function (DUF541)	NA|602aa|up_2|NZ_CP023694.1_2488943_2490749_+	PRK09420, cpdB, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA|492aa|up_1|NZ_CP023694.1_2490762_2492238_-	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|469aa|up_0|NZ_CP023694.1_2492234_2493641_-	cd06450, DOPA_deC_like, DOPA decarboxylase family	NA|832aa|down_0|NZ_CP023694.1_2494151_2496647_-	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type	NA|184aa|down_1|NZ_CP023694.1_2496714_2497266_-	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs)	NA|279aa|down_2|NZ_CP023694.1_2497519_2498356_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|117aa|down_3|NZ_CP023694.1_2498400_2498751_-	PRK09239, PRK09239, chorismate mutase; Provisional	NA|138aa|down_4|NZ_CP023694.1_2498796_2499210_-	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain	NA|296aa|down_5|NZ_CP023694.1_2499371_2500259_+	NA	NA|309aa|down_6|NZ_CP023694.1_2500300_2501227_-	PRK07791, PRK07791, short chain dehydrogenase; Provisional	NA|254aa|down_7|NZ_CP023694.1_2501223_2501985_-	PRK07856, PRK07856, SDR family oxidoreductase	NA|248aa|down_8|NZ_CP023694.1_2502039_2502783_+	PRK07938, PRK07938, enoyl-CoA hydratase family protein	NA|279aa|down_9|NZ_CP023694.1_2502783_2503620_+	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	7	2981182-2981258	6	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	CGCGTCACCGACACCACCGGCCC	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|117aa|up_0|NZ_CP023694.1_2979972_2980323_+,NA	NA|215aa|up_9|NZ_CP023694.1_2970662_2971307_+	pfam07510, DUF1524, Protein of unknown function (DUF1524)	NA|546aa|up_8|NZ_CP023694.1_2971386_2973024_+	cd07389, MPP_PhoD, Bacillus subtilis PhoD and related proteins, metallophosphatase domain	NA|628aa|up_7|NZ_CP023694.1_2973339_2975223_+	pfam13454, NAD_binding_9, FAD-NAD(P)-binding	NA|151aa|up_6|NZ_CP023694.1_2975303_2975756_+	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|196aa|up_5|NZ_CP023694.1_2976013_2976601_+	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|77aa|up_4|NZ_CP023694.1_2976630_2976861_-	pfam10041, DUF2277, Uncharacterized conserved protein (DUF2277)	NA|307aa|up_3|NZ_CP023694.1_2976963_2977884_+	PRK06522, PRK06522, 2-dehydropantoate 2-reductase; Reviewed	NA|348aa|up_2|NZ_CP023694.1_2978138_2979182_-	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD)	NA|196aa|up_1|NZ_CP023694.1_2979277_2979865_+	pfam17926, TetR_C_21, Tetracyclin repressor-like, C-terminal domain	NA|117aa|up_0|NZ_CP023694.1_2979972_2980323_+	NA	NA|467aa|down_0|NZ_CP023694.1_2981627_2983028_+	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning]	NA|74aa|down_1|NZ_CP023694.1_2983050_2983272_+	TIGR02605, CxxC_CxxC_SSSS, putative regulatory protein, FmdB family	NA|264aa|down_2|NZ_CP023694.1_2983340_2984132_+	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|270aa|down_3|NZ_CP023694.1_2984052_2984862_-	cd07520, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily	NA|864aa|down_4|NZ_CP023694.1_2984861_2987453_-	pfam11202, PRTase_1, Phosphoribosyl transferase (PRTase)	NA|389aa|down_5|NZ_CP023694.1_2987581_2988748_-	pfam15617, C-C_Bond_Lyase, C-C_Bond_Lyase of the TIM-Barrel fold	NA|308aa|down_6|NZ_CP023694.1_2988978_2989902_+	pfam02342, TerD, TerD domain	NA|246aa|down_7|NZ_CP023694.1_2989975_2990713_-	COG4110, COG4110, Uncharacterized protein involved in stress response [General function prediction only]	NA|383aa|down_8|NZ_CP023694.1_2990843_2991992_-	PRK14013, PRK14013, hypothetical protein; Provisional	NA|192aa|down_9|NZ_CP023694.1_2992117_2992693_-	pfam02342, TerD, TerD domain
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	8	4193538-4193669	7,2	CRISPRCasFinder,CRT	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	CGCAGGACCTGCACGCCACGGGCG,AGGACCTGCACGCCACGG	24,18	1	1	4193634-4193651	NZ_CP023694.1_5323732-5323715	NA:NA	1,3	3	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA,NA|132aa|down_0|NZ_CP023694.1_4193803_4194199_-,NA|89aa|down_1|NZ_CP023694.1_4194198_4194465_-	NA|284aa|up_9|NZ_CP023694.1_4180291_4181143_+	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|271aa|up_8|NZ_CP023694.1_4181311_4182124_-	cd09080, TDP2, Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains	NA|131aa|up_7|NZ_CP023694.1_4182236_4182629_+	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase	NA|484aa|up_6|NZ_CP023694.1_4182650_4184102_-	cd07089, ALDH_CddD-AldA-like, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like and related proteins	NA|577aa|up_5|NZ_CP023694.1_4184098_4185829_-	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics	NA|373aa|up_4|NZ_CP023694.1_4185917_4187036_-	COG2141, COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]	NA|257aa|up_3|NZ_CP023694.1_4187148_4187919_-	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs	NA|312aa|up_2|NZ_CP023694.1_4187927_4188863_-	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family	NA|412aa|up_1|NZ_CP023694.1_4188844_4190080_-	pfam04909, Amidohydro_2, Amidohydrolase	NA|1001aa|up_0|NZ_CP023694.1_4190297_4193300_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|132aa|down_0|NZ_CP023694.1_4193803_4194199_-	NA	NA|89aa|down_1|NZ_CP023694.1_4194198_4194465_-	NA	NA|309aa|down_2|NZ_CP023694.1_4194581_4195508_+	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism]	NA|537aa|down_3|NZ_CP023694.1_4195497_4197108_-	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated	NA|387aa|down_4|NZ_CP023694.1_4197204_4198365_+	PRK07855, PRK07855, lipid-transfer protein; Provisional	NA|138aa|down_5|NZ_CP023694.1_4198366_4198780_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|258aa|down_6|NZ_CP023694.1_4198776_4199550_+	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily	NA|317aa|down_7|NZ_CP023694.1_4199632_4200583_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|203aa|down_8|NZ_CP023694.1_4200606_4201215_-	PRK06341, PRK06341, single-stranded DNA-binding protein; Provisional	NA|241aa|down_9|NZ_CP023694.1_4203893_4204616_-	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	9	4790693-4790798	8	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	GCGGGTAGCCGTACCCGCCGGGGCG	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|66aa|up_9|NZ_CP023694.1_4779526_4779724_+,NA|57aa|up_5|NZ_CP023694.1_4782452_4782623_-,NA|258aa|down_9|NZ_CP023694.1_4803392_4804166_+	NA|66aa|up_9|NZ_CP023694.1_4779526_4779724_+	NA	NA|213aa|up_8|NZ_CP023694.1_4779720_4780359_+	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II	NA|410aa|up_7|NZ_CP023694.1_4780355_4781585_+	cd05830, Sortase_E, Sortase domain found in the class E family of sortases	NA|251aa|up_6|NZ_CP023694.1_4781598_4782351_+	cd05830, Sortase_E, Sortase domain found in the class E family of sortases	NA|57aa|up_5|NZ_CP023694.1_4782452_4782623_-	NA	NA|676aa|up_4|NZ_CP023694.1_4783007_4785035_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|493aa|up_3|NZ_CP023694.1_4785203_4786682_-	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|481aa|up_2|NZ_CP023694.1_4786678_4788121_-	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning]	NA|521aa|up_1|NZ_CP023694.1_4788148_4789711_-	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms]	NA|170aa|up_0|NZ_CP023694.1_4789843_4790353_-	pfam00498, FHA, FHA domain	NA|178aa|down_0|NZ_CP023694.1_4791889_4792423_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|447aa|down_1|NZ_CP023694.1_4794567_4795908_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|312aa|down_2|NZ_CP023694.1_4795852_4796788_-	cd05241, 3b-HSD-like_SDR_e, 3beta-hydroxysteroid dehydrogenases (3b-HSD)-like, extended (e) SDRs	NA|381aa|down_3|NZ_CP023694.1_4796784_4797927_-	pfam03756, AfsA, A-factor biosynthesis hotdog domain	NA|233aa|down_4|NZ_CP023694.1_4798086_4798785_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|478aa|down_5|NZ_CP023694.1_4798919_4800353_+	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252)	NA|253aa|down_6|NZ_CP023694.1_4800577_4801336_+	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]	NA|110aa|down_7|NZ_CP023694.1_4801394_4801724_+	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein	NA|378aa|down_8|NZ_CP023694.1_4801827_4802961_-	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|258aa|down_9|NZ_CP023694.1_4803392_4804166_+	NA
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	10	5411299-5411397	9	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	ACGTTGTCGCCGTAGTAGTAGTTGT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|202aa|up_1|NZ_CP023694.1_5409252_5409858_-,NA	NA|430aa|up_9|NZ_CP023694.1_5398610_5399900_+	cd10976, CE4_CDA_like_3, Putative catalytic domain of uncharacterized bacterial hypothetical proteins similar to insect chitin deacetylase-like proteins	NA|216aa|up_8|NZ_CP023694.1_5399966_5400614_+	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|257aa|up_7|NZ_CP023694.1_5400627_5401398_+	pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region	NA|581aa|up_6|NZ_CP023694.1_5401401_5403144_+	pfam05140, ResB, ResB-like family	NA|360aa|up_5|NZ_CP023694.1_5403140_5404220_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|466aa|up_4|NZ_CP023694.1_5404322_5405720_-	cd19539, SgcC5_NRPS-like, SgcC5 is a non-ribosomal peptide synthetase (NRPS) condensation enzyme with ester- and amide- bond forming activity and similar C-domains of modular NRPSs	NA|245aa|up_3|NZ_CP023694.1_5405880_5406615_-	cd04772, HTH_TioE_rpt1, First Helix-Turn-Helix DNA binding domain of the regulatory protein TioE	NA|835aa|up_2|NZ_CP023694.1_5406696_5409201_+	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair]	NA|202aa|up_1|NZ_CP023694.1_5409252_5409858_-	NA	NA|320aa|up_0|NZ_CP023694.1_5409963_5410923_+	pfam13560, HTH_31, Helix-turn-helix domain	NA|101aa|down_0|NZ_CP023694.1_5412026_5412329_-	pfam13396, PLDc_N, Phospholipase_D-nuclease N-terminal	NA|484aa|down_1|NZ_CP023694.1_5412397_5413849_+	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family	NA|301aa|down_2|NZ_CP023694.1_5413845_5414748_+	PRK12888, ubiA, 4-hydroxybenzoate octaprenyltransferase	NA|201aa|down_3|NZ_CP023694.1_5414737_5415340_-	pfam01694, Rhomboid, Rhomboid family	NA|229aa|down_4|NZ_CP023694.1_5415431_5416118_+	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism]	NA|152aa|down_5|NZ_CP023694.1_5416197_5416653_+	smart00344, HTH_ASNC, helix_turn_helix ASNC type	NA|388aa|down_6|NZ_CP023694.1_5416691_5417855_+	TIGR03700, mena_SCO4494, putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family	NA|217aa|down_7|NZ_CP023694.1_5417948_5418599_+	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain	NA|175aa|down_8|NZ_CP023694.1_5418615_5419140_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|102aa|down_9|NZ_CP023694.1_5419243_5419549_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	11	6598001-6598171	10	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	GGAGCCGTTGTCCTGGCGCGGTGCGGGGTACTGACCGGTCGAGCCGTTGTC	51	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA,NA|64aa|down_0|NZ_CP023694.1_6601826_6602018_+,NA|34aa|down_6|NZ_CP023694.1_6607036_6607138_-	NA|793aa|up_9|NZ_CP023694.1_6585764_6588143_+	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family	NA|528aa|up_8|NZ_CP023694.1_6588297_6589881_+	TIGR01117, methylmalonyl-CoA_decarboxylase_alpha-subunit, methylmalonyl-CoA decarboxylase alpha subunit	NA|65aa|up_7|NZ_CP023694.1_6589916_6590111_+	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit	NA|194aa|up_6|NZ_CP023694.1_6590523_6591105_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|195aa|up_5|NZ_CP023694.1_6591085_6591670_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|138aa|up_4|NZ_CP023694.1_6591764_6592178_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|1112aa|up_3|NZ_CP023694.1_6592188_6595524_-	pfam08376, NIT, Nitrate and nitrite sensing	NA|192aa|up_2|NZ_CP023694.1_6595902_6596478_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|132aa|up_1|NZ_CP023694.1_6596458_6596854_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|138aa|up_0|NZ_CP023694.1_6596965_6597379_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|64aa|down_0|NZ_CP023694.1_6601826_6602018_+	NA	NA|259aa|down_1|NZ_CP023694.1_6602190_6602967_+	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]	NA|495aa|down_2|NZ_CP023694.1_6602959_6604444_+	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed	NA|145aa|down_3|NZ_CP023694.1_6604531_6604966_-	pfam13471, Transglut_core3, Transglutaminase-like superfamily	NA|87aa|down_4|NZ_CP023694.1_6604962_6605223_-	pfam05402, PqqD, Coenzyme PQQ synthesis protein D (PqqD)	NA|610aa|down_5|NZ_CP023694.1_6605200_6607030_-	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B	NA|34aa|down_6|NZ_CP023694.1_6607036_6607138_-	NA	NA|244aa|down_7|NZ_CP023694.1_6607363_6608095_+	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only]	NA|239aa|down_8|NZ_CP023694.1_6608851_6609568_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|477aa|down_9|NZ_CP023694.1_6609765_6611196_+	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit
GCF_008705135.1_ASM870513v1	NZ_CP023694	Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete genome	12	7560452-7560576	11	CRISPRCasFinder	no		csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	Orphan	TACCCGCACCCTCAGCCGTACCC	23	0	0	NA	NA	NA	2	2	Orphan	csa3,DEDDh,WYL,Cas9_archaeal,cas3,c2c9_V-U4,DinG	NA|67aa|up_1|NZ_CP023694.1_7558559_7558760_-,NA|286aa|down_0|NZ_CP023694.1_7560631_7561489_+,NA|194aa|down_5|NZ_CP023694.1_7565432_7566014_+	NA|386aa|up_9|NZ_CP023694.1_7550700_7551858_-	pfam12893, Lumazine_bd_2, Putative lumazine-binding	NA|300aa|up_8|NZ_CP023694.1_7551952_7552852_+	COG0583, LysR, Transcriptional regulator [Transcription]	NA|266aa|up_7|NZ_CP023694.1_7552870_7553668_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|447aa|up_6|NZ_CP023694.1_7553831_7555172_+	cd01315, L-HYD_ALN, L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in biotechnology)	NA|372aa|up_5|NZ_CP023694.1_7555206_7556322_+	PRK13257, PRK13257, allantoicase; Provisional	NA|254aa|up_4|NZ_CP023694.1_7556400_7557162_-	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated	NA|209aa|up_3|NZ_CP023694.1_7557337_7557964_+	pfam01872, RibD_C, RibD C-terminal domain	NA|132aa|up_2|NZ_CP023694.1_7558115_7558511_+	cd00607, RNase_Sa, RNase_Sa	NA|67aa|up_1|NZ_CP023694.1_7558559_7558760_-	NA	NA|415aa|up_0|NZ_CP023694.1_7558973_7560218_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|286aa|down_0|NZ_CP023694.1_7560631_7561489_+	NA	NA|228aa|down_1|NZ_CP023694.1_7561587_7562271_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|341aa|down_2|NZ_CP023694.1_7562290_7563313_-	TIGR04380, hypothetical_protein_HOLDEFILI_04020, inositol 2-dehydrogenase	NA|250aa|down_3|NZ_CP023694.1_7563429_7564179_+	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|383aa|down_4|NZ_CP023694.1_7564287_7565436_+	TIGR00744, Glucokinase_Glucose_kinase	NA|194aa|down_5|NZ_CP023694.1_7565432_7566014_+	NA	NA|948aa|down_6|NZ_CP023694.1_7566120_7568964_+	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]	NA|705aa|down_7|NZ_CP023694.1_7568960_7571075_+	COG4279, COG4279, Uncharacterized conserved protein [Function unknown]	NA|109aa|down_8|NZ_CP023694.1_7571128_7571455_-	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]	NA|136aa|down_9|NZ_CP023694.1_7571478_7571886_-	cd02233, cupin_HNL-like, Granulicella tundricola hydroxynitrile lyase (GtHNL) and related proteins, cupin domain
