assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	1	479498-479603	1	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CCCCTCCCGGGCGCAGGCGGCTCC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA|466aa|down_2|NZ_CP023696.1_481609_483007_-,NA|175aa|down_5|NZ_CP023696.1_488053_488578_+	NA|212aa|up_9|NZ_CP023696.1_467438_468074_-	COG3247, HdeD, Uncharacterized conserved protein [Function unknown]	NA|250aa|up_8|NZ_CP023696.1_468479_469229_+	pfam07885, Ion_trans_2, Ion channel	NA|473aa|up_7|NZ_CP023696.1_469225_470644_+	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252)	NA|866aa|up_6|NZ_CP023696.1_470798_473396_-	COG2909, MalT, ATP-dependent transcriptional regulator [Transcription]	NA|238aa|up_5|NZ_CP023696.1_473844_474558_-	cd04772, HTH_TioE_rpt1, First Helix-Turn-Helix DNA binding domain of the regulatory protein TioE	NA|321aa|up_4|NZ_CP023696.1_475274_476237_-	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|262aa|up_3|NZ_CP023696.1_476303_477089_-	cd01714, ETF_beta, The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases	NA|200aa|up_2|NZ_CP023696.1_477279_477879_-	smart00903, Flavin_Reduct, Flavin reductase like domain	NA|125aa|up_1|NZ_CP023696.1_478015_478390_-	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains	NA|238aa|up_0|NZ_CP023696.1_478636_479350_+	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like	NA|360aa|down_0|NZ_CP023696.1_479685_480765_-	cd06502, TA_like, Low-specificity threonine aldolase (TA)	NA|253aa|down_1|NZ_CP023696.1_480761_481520_-	cd05233, SDR_c, classical (c) SDRs	NA|466aa|down_2|NZ_CP023696.1_481609_483007_-	NA	NA|183aa|down_3|NZ_CP023696.1_485998_486547_-	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain	NA|312aa|down_4|NZ_CP023696.1_486964_487900_+	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|175aa|down_5|NZ_CP023696.1_488053_488578_+	NA	NA|232aa|down_6|NZ_CP023696.1_488795_489491_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|203aa|down_7|NZ_CP023696.1_489692_490301_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|362aa|down_8|NZ_CP023696.1_490573_491659_+	pfam15902, Sortilin-Vps10, Sortilin, neurotensin receptor 3,	NA|226aa|down_9|NZ_CP023696.1_491694_492372_+	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	2	887902-888055	2	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GGGCGGACCGTCCCCAGGGGCGGCGC	26	1	1	888003-888029	NZ_CP023696.1_888038-888064	NA	2	2	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|176aa|up_0|NZ_CP023696.1_887052_887580_+,NA	NA|412aa|up_9|NZ_CP023696.1_875610_876846_+	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains	NA|448aa|up_8|NZ_CP023696.1_876842_878186_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|126aa|up_7|NZ_CP023696.1_878228_878606_+	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|294aa|up_6|NZ_CP023696.1_879005_879887_-	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily	NA|481aa|up_5|NZ_CP023696.1_880085_881528_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|338aa|up_4|NZ_CP023696.1_881725_882739_-	pfam04198, Sugar-bind, Putative sugar-binding domain	NA|228aa|up_3|NZ_CP023696.1_882857_883541_-	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated	NA|479aa|up_2|NZ_CP023696.1_883685_885122_-	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA|311aa|up_1|NZ_CP023696.1_885538_886471_-	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed	NA|176aa|up_0|NZ_CP023696.1_887052_887580_+	NA	NA|715aa|down_0|NZ_CP023696.1_888118_890263_-	PRK14873, PRK14873, primosomal protein N'	NA|408aa|down_1|NZ_CP023696.1_890705_891929_-	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|403aa|down_2|NZ_CP023696.1_892174_893383_-	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|91aa|down_3|NZ_CP023696.1_893516_893789_-	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed	NA|198aa|down_4|NZ_CP023696.1_893822_894416_-	PRK00300, gmk, guanylate kinase; Provisional	NA|108aa|down_5|NZ_CP023696.1_894467_894791_-	COG0099, RpsM, Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]	NA|278aa|down_6|NZ_CP023696.1_895135_895969_-	PRK00125, pyrF, orotidine 5'-phosphate decarboxylase; Reviewed	NA|374aa|down_7|NZ_CP023696.1_895965_897087_-	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase	NA|1103aa|down_8|NZ_CP023696.1_897187_900496_-	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|380aa|down_9|NZ_CP023696.1_900488_901628_-	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	3	959944-960026	3	CRISPRCasFinder	no	DEDDh	csa3,DEDDh,WYL,cas4,cas3,DinG	Unclear	CAGCGCCCCGGAGGCGCAACGCGCCGA	27	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|541aa|up_9|NZ_CP023696.1_949335_950958_+,NA|148aa|down_0|NZ_CP023696.1_960043_960487_-,NA|69aa|down_5|NZ_CP023696.1_965068_965275_-	NA|541aa|up_9|NZ_CP023696.1_949335_950958_+	NA	NA|187aa|up_8|NZ_CP023696.1_950958_951519_-	cd01275, FHIT, FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into three  branches: the Hint branch, which consists of adenosine 5' -monophosphoramide hydrolases, the Fhit branch, that consists of diadenosine polyphosphate hydrolases, and the GalT branch consisting of specific nucloside monophosphate transferases	NA|660aa|up_7|NZ_CP023696.1_951604_953584_-	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed	NA|418aa|up_6|NZ_CP023696.1_953730_954984_-	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau	NA|187aa|up_5|NZ_CP023696.1_954983_955544_-	pfam14280, DUF4365, Domain of unknown function (DUF4365)	DEDDh|243aa|up_4|NZ_CP023696.1_955694_956423_+	PRK07942, PRK07942, DNA polymerase III subunit epsilon; Provisional	NA|198aa|up_3|NZ_CP023696.1_956645_957239_-	cd07824, SRPBCC_6, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|156aa|up_2|NZ_CP023696.1_957453_957921_-	TIGR02611, Putative_membrane_protein, TIGR02611 family protein	NA|138aa|up_1|NZ_CP023696.1_958119_958533_+	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA	NA|187aa|up_0|NZ_CP023696.1_958911_959472_+	pfam11706, zf-CGNR, CGNR zinc finger	NA|148aa|down_0|NZ_CP023696.1_960043_960487_-	NA	NA|174aa|down_1|NZ_CP023696.1_960777_961299_+	pfam13462, Thioredoxin_4, Thioredoxin	NA|268aa|down_2|NZ_CP023696.1_961354_962158_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|271aa|down_3|NZ_CP023696.1_962201_963014_-	cd01559, ADCL_like, ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate	NA|352aa|down_4|NZ_CP023696.1_963016_964072_-	TIGR01824, Anthranilate_synthase_component_I-like_protein, aminodeoxychorismate synthase, component I, clade 2	NA|69aa|down_5|NZ_CP023696.1_965068_965275_-	NA	NA|420aa|down_6|NZ_CP023696.1_965904_967164_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|273aa|down_7|NZ_CP023696.1_967154_967973_-	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis]	NA|411aa|down_8|NZ_CP023696.1_968066_969299_-	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)	NA|1326aa|down_9|NZ_CP023696.1_969854_973832_-	pfam02277, DBI_PRT, Phosphoribosyltransferase
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	4	1120002-1120160	4	CRISPRCasFinder	no	csa3	csa3,DEDDh,WYL,cas4,cas3,DinG	Type I-A	CCCGAGCCGTACGCCCGGGTGGTGCGGGGTGCC	33	0	0	NA	NA	NA	2	2	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|99aa|up_3|NZ_CP023696.1_1115809_1116106_+,NA|209aa|down_3|NZ_CP023696.1_1123398_1124025_+,NA|468aa|down_7|NZ_CP023696.1_1126606_1128010_-	NA|468aa|up_9|NZ_CP023696.1_1108645_1110049_+	pfam02447, GntP_permease, GntP family permease	NA|552aa|up_8|NZ_CP023696.1_1111211_1112867_-	PRK12834, PRK12834, putative FAD-binding dehydrogenase; Reviewed	NA|180aa|up_7|NZ_CP023696.1_1112976_1113516_+	cd04697, Nudix_Hydrolase_38, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|131aa|up_6|NZ_CP023696.1_1113508_1113901_+	COG2149, COG2149, Predicted membrane protein [Function unknown]	NA|97aa|up_5|NZ_CP023696.1_1114071_1114362_+	pfam02656, DUF202, Domain of unknown function (DUF202)	NA|311aa|up_4|NZ_CP023696.1_1114793_1115726_-	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases	NA|99aa|up_3|NZ_CP023696.1_1115809_1116106_+	NA	NA|304aa|up_2|NZ_CP023696.1_1116220_1117132_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|341aa|up_1|NZ_CP023696.1_1117724_1118747_+	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins	NA|405aa|up_0|NZ_CP023696.1_1118750_1119965_+	cd01155, ACAD_FadE2, Acyl-CoA dehydrogenases similar to fadE2	NA|199aa|down_0|NZ_CP023696.1_1120197_1120794_-	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain	NA|258aa|down_1|NZ_CP023696.1_1120865_1121639_-	cd05233, SDR_c, classical (c) SDRs	NA|443aa|down_2|NZ_CP023696.1_1121868_1123197_+	pfam07075, DUF1343, Protein of unknown function (DUF1343)	NA|209aa|down_3|NZ_CP023696.1_1123398_1124025_+	NA	NA|154aa|down_4|NZ_CP023696.1_1124866_1125328_+	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit	NA|219aa|down_5|NZ_CP023696.1_1125344_1126001_-	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain	NA|96aa|down_6|NZ_CP023696.1_1126096_1126384_-	COG4298, COG4298, Uncharacterized protein conserved in bacteria [Function unknown]	NA|468aa|down_7|NZ_CP023696.1_1126606_1128010_-	NA	NA|576aa|down_8|NZ_CP023696.1_1128530_1130258_+	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B	NA|211aa|down_9|NZ_CP023696.1_1130328_1130961_+	pfam13471, Transglut_core3, Transglutaminase-like superfamily
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	5	1521474-1521712	5	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CGGGGTCCGCGGAAGACTCGGGG	23	0	0	NA	NA	NA	4	4	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|60aa|up_1|NZ_CP023696.1_1519852_1520032_-,NA|84aa|down_0|NZ_CP023696.1_1521850_1522102_-	NA|487aa|up_9|NZ_CP023696.1_1507024_1508485_-	PRK12810, gltD, glutamate synthase subunit beta; Reviewed	NA|1521aa|up_8|NZ_CP023696.1_1508477_1513040_-	PRK11750, gltB, glutamate synthase subunit alpha; Provisional	NA|243aa|up_7|NZ_CP023696.1_1513485_1514214_-	cd02433, Nodulin-21_like_2, Nodulin-21 and CCC1-related protein family	NA|309aa|up_6|NZ_CP023696.1_1514433_1515360_+	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP	NA|346aa|up_5|NZ_CP023696.1_1515423_1516461_-	PRK13108, PRK13108, prolipoprotein diacylglyceryl transferase; Reviewed	NA|342aa|up_4|NZ_CP023696.1_1516581_1517607_-	pfam13462, Thioredoxin_4, Thioredoxin	NA|272aa|up_3|NZ_CP023696.1_1517670_1518486_-	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional	NA|428aa|up_2|NZ_CP023696.1_1518482_1519766_-	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated	NA|60aa|up_1|NZ_CP023696.1_1519852_1520032_-	NA	NA|270aa|up_0|NZ_CP023696.1_1520098_1520908_-	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC	NA|84aa|down_0|NZ_CP023696.1_1521850_1522102_-	NA	NA|230aa|down_1|NZ_CP023696.1_1522234_1522924_-	TIGR02234, conserved_hypothetical_protein, trp region conserved hypothetical membrane protein	NA|505aa|down_2|NZ_CP023696.1_1522929_1524444_-	PRK13571, PRK13571, anthranilate synthase component I; Provisional	NA|117aa|down_3|NZ_CP023696.1_1524455_1524806_-	PRK00051, hisI, phosphoribosyl-AMP cyclohydrolase; Reviewed	NA|211aa|down_4|NZ_CP023696.1_1524889_1525522_+	TIGR03085, TIGR03085, TIGR03085 family protein	NA|129aa|down_5|NZ_CP023696.1_1525526_1525913_+	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|257aa|down_6|NZ_CP023696.1_1526221_1526992_-	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional	NA|136aa|down_7|NZ_CP023696.1_1526988_1527396_-	cd06154, YjgF_YER057c_UK114_like_6, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function	NA|242aa|down_8|NZ_CP023696.1_1527392_1528118_-	PRK14024, PRK14024, phosphoribosyl isomerase A; Provisional	NA|214aa|down_9|NZ_CP023696.1_1528157_1528799_-	PRK13146, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	6	1956398-1956502	6	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	TGCTCTGCCAATTGAGCTACAGGGGAT	27	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|483aa|up_8|NZ_CP023696.1_1945656_1947105_+,NA|67aa|up_1|NZ_CP023696.1_1953707_1953908_-,NA|100aa|down_0|NZ_CP023696.1_1956683_1956983_+,NA|91aa|down_4|NZ_CP023696.1_1962452_1962725_+	NA|558aa|up_9|NZ_CP023696.1_1943986_1945660_+	COG3207, DIT1, Pyoverdine/dityrosine biosynthesis protein [Secondary metabolites biosynthesis, transport, and catabolism]	NA|483aa|up_8|NZ_CP023696.1_1945656_1947105_+	NA	NA|477aa|up_7|NZ_CP023696.1_1947109_1948540_+	pfam12897, Aminotran_MocR, Alanine-glyoxylate amino-transferase	NA|239aa|up_6|NZ_CP023696.1_1948637_1949354_+	TIGR04305, TENA/THI-4_family_protein, putative folate metabolism protein, CADD family	NA|411aa|up_5|NZ_CP023696.1_1949350_1950583_+	PRK08133, PRK08133, O-succinylhomoserine sulfhydrylase; Validated	NA|313aa|up_4|NZ_CP023696.1_1950579_1951518_+	PRK05368, PRK05368, homoserine O-succinyltransferase; Provisional	NA|193aa|up_3|NZ_CP023696.1_1951468_1952047_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|481aa|up_2|NZ_CP023696.1_1952166_1953609_+	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters	NA|67aa|up_1|NZ_CP023696.1_1953707_1953908_-	NA	NA|465aa|up_0|NZ_CP023696.1_1954366_1955761_+	smart00382, AAA, ATPases associated with a variety of cellular activities	NA|100aa|down_0|NZ_CP023696.1_1956683_1956983_+	NA	NA|480aa|down_1|NZ_CP023696.1_1957087_1958527_+	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|578aa|down_2|NZ_CP023696.1_1958698_1960432_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|643aa|down_3|NZ_CP023696.1_1960431_1962360_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|91aa|down_4|NZ_CP023696.1_1962452_1962725_+	NA	NA|416aa|down_5|NZ_CP023696.1_1962712_1963960_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|644aa|down_6|NZ_CP023696.1_1964076_1966008_-	PRK05667, dnaG, DNA primase; Validated	NA|426aa|down_7|NZ_CP023696.1_1966257_1967535_-	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|454aa|down_8|NZ_CP023696.1_1967653_1969015_-	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|254aa|down_9|NZ_CP023696.1_1969254_1970016_-	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	7	2102405-2102687	7	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CCGCCACAGCCACCGGGCGGGGGCGACGACCAGGTAC	37	0	0	NA	NA	NA	3	3	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|364aa|up_7|NZ_CP023696.1_2088243_2089335_+,NA	NA|392aa|up_9|NZ_CP023696.1_2085212_2086388_-	cd03798, GT4_WlbH-like, Bordetella parapertussis WlbH and similar proteins	NA|369aa|up_8|NZ_CP023696.1_2086602_2087709_-	cd03786, GTB_UDP-GlcNAc_2-Epimerase, UDP-N-acetylglucosamine 2-epimerase and similar proteins	NA|364aa|up_7|NZ_CP023696.1_2088243_2089335_+	NA	NA|324aa|up_6|NZ_CP023696.1_2089787_2090759_-	cd05247, UDP_G4E_1_SDR_e, UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs	NA|428aa|up_5|NZ_CP023696.1_2090864_2092148_-	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]	NA|543aa|up_4|NZ_CP023696.1_2092144_2093773_-	pfam00535, Glycos_transf_2, Glycosyl transferase family 2	NA|338aa|up_3|NZ_CP023696.1_2093784_2094798_-	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only]	NA|373aa|up_2|NZ_CP023696.1_2094794_2095913_-	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn)	NA|1494aa|up_1|NZ_CP023696.1_2096250_2100732_-	TIGR00757, Ribonuclease_E/G-like_protein, ribonuclease, Rne/Rng family	NA|261aa|up_0|NZ_CP023696.1_2100966_2101749_-	pfam10105, DUF2344, Uncharacterized protein conserved in bacteria (DUF2344)	NA|641aa|down_0|NZ_CP023696.1_2103119_2105042_-	TIGR03960, radical_SAM_domain_protein, radical SAM family uncharacterized protein	NA|507aa|down_1|NZ_CP023696.1_2105187_2106708_-	smart00880, CHAD, The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family	NA|209aa|down_2|NZ_CP023696.1_2106800_2107427_-	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal	NA|191aa|down_3|NZ_CP023696.1_2107546_2108119_+	COG3402, COG3402, Uncharacterized conserved protein [Function unknown]	NA|506aa|down_4|NZ_CP023696.1_2108115_2109633_+	COG3428, COG3428, Predicted membrane protein [Function unknown]	NA|401aa|down_5|NZ_CP023696.1_2109727_2110930_-	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA	NA|730aa|down_6|NZ_CP023696.1_2110939_2113129_-	TIGR03423, pbp2_mrdA, penicillin-binding protein 2	NA|226aa|down_7|NZ_CP023696.1_2113196_2113874_-	TIGR03426, shape_MreD, rod shape-determining protein MreD	NA|342aa|down_8|NZ_CP023696.1_2113878_2114904_-	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional	NA|340aa|down_9|NZ_CP023696.1_2115003_2116023_-	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	8	2693184-2693359	8	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GGCGGGCGGCTGCGCGGGCTGCCCCGGGGCGGCGGGTGGCT	41	1	1	2693225-2693249	NZ_CP023696.1_1583998-1584022	NA	2	2	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA|356aa|down_2|NZ_CP023696.1_2697108_2698176_+	NA|910aa|up_9|NZ_CP023696.1_2677027_2679757_-	pfam00311, PEPcase, Phosphoenolpyruvate carboxylase	NA|330aa|up_8|NZ_CP023696.1_2680053_2681043_+	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism]	NA|225aa|up_7|NZ_CP023696.1_2681039_2681714_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|276aa|up_6|NZ_CP023696.1_2682015_2682843_-	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|166aa|up_5|NZ_CP023696.1_2682972_2683470_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|258aa|up_4|NZ_CP023696.1_2683428_2684202_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|394aa|up_3|NZ_CP023696.1_2684641_2685823_-	COG0153, GalK, Galactokinase [Carbohydrate transport and metabolism]	NA|350aa|up_2|NZ_CP023696.1_2686865_2687915_-	cd00608, GalT, Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate	NA|231aa|up_1|NZ_CP023696.1_2688476_2689169_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|643aa|up_0|NZ_CP023696.1_2689403_2691332_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|612aa|down_0|NZ_CP023696.1_2693726_2695562_-	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]	NA|251aa|down_1|NZ_CP023696.1_2695792_2696545_+	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|356aa|down_2|NZ_CP023696.1_2697108_2698176_+	NA	NA|493aa|down_3|NZ_CP023696.1_2698372_2699851_-	pfam01757, Acyl_transf_3, Acyltransferase family	NA|298aa|down_4|NZ_CP023696.1_2700020_2700914_-	PRK03188, PRK03188, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional	NA|286aa|down_5|NZ_CP023696.1_2700910_2701768_-	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA	NA|413aa|down_6|NZ_CP023696.1_2701764_2703003_-	COG3583, COG3583, Uncharacterized protein conserved in bacteria [Function unknown]	NA|291aa|down_7|NZ_CP023696.1_2703682_2704555_-	cd01310, TatD_DNAse, TatD like proteins;  E	NA|152aa|down_8|NZ_CP023696.1_2704724_2705180_-	TIGR02783, probable_conjugal_transfer_protein_TrbL, P-type conjugative transfer protein TrbL	NA|296aa|down_9|NZ_CP023696.1_2705424_2706312_-	COG0313, COG0313, Predicted methyltransferases [General function prediction only]
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	9	2959498-2959578	9	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CAGGGCGGCGAGTGCGTCGAGGTCGCC	27	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|62aa|up_9|NZ_CP023696.1_2948708_2948894_-,NA|149aa|up_1|NZ_CP023696.1_2958089_2958536_-,NA|200aa|down_1|NZ_CP023696.1_2961369_2961969_+,NA|119aa|down_6|NZ_CP023696.1_2966772_2967129_+	NA|62aa|up_9|NZ_CP023696.1_2948708_2948894_-	NA	NA|332aa|up_8|NZ_CP023696.1_2949286_2950282_+	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|194aa|up_7|NZ_CP023696.1_2950583_2951165_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|209aa|up_6|NZ_CP023696.1_2951233_2951860_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|158aa|up_5|NZ_CP023696.1_2952644_2953118_-	cd04684, Nudix_Hydrolase_25, Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function	NA|233aa|up_4|NZ_CP023696.1_2953370_2954069_-	pfam11774, Lsr2, Lsr2	NA|753aa|up_3|NZ_CP023696.1_2954300_2956559_+	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	NA|417aa|up_2|NZ_CP023696.1_2956670_2957921_-	pfam00296, Bac_luciferase, Luciferase-like monooxygenase	NA|149aa|up_1|NZ_CP023696.1_2958089_2958536_-	NA	NA|260aa|up_0|NZ_CP023696.1_2958676_2959456_+	pfam13560, HTH_31, Helix-turn-helix domain	NA|407aa|down_0|NZ_CP023696.1_2959761_2960982_-	pfam03995, Inhibitor_I36, Peptidase inhibitor family I36	NA|200aa|down_1|NZ_CP023696.1_2961369_2961969_+	NA	NA|215aa|down_2|NZ_CP023696.1_2961994_2962639_-	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]	NA|449aa|down_3|NZ_CP023696.1_2962899_2964246_-	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed	NA|312aa|down_4|NZ_CP023696.1_2964558_2965494_-	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed	NA|350aa|down_5|NZ_CP023696.1_2965629_2966679_-	COG1737, RpiR, Transcriptional regulators [Transcription]	NA|119aa|down_6|NZ_CP023696.1_2966772_2967129_+	NA	NA|90aa|down_7|NZ_CP023696.1_2967125_2967395_+	pfam13223, DUF4031, Protein of unknown function (DUF4031)	NA|450aa|down_8|NZ_CP023696.1_2967548_2968898_-	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|253aa|down_9|NZ_CP023696.1_2969160_2969919_-	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	10	3580791-3580893	10	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GGTCTGATGGTCCGCCGGTCCGC	23	0	0	NA	NA	NA	2	2	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|106aa|up_7|NZ_CP023696.1_3573815_3574133_+,NA|95aa|up_0|NZ_CP023696.1_3580484_3580769_+,NA|95aa|down_8|NZ_CP023696.1_3589353_3589638_-	NA|195aa|up_9|NZ_CP023696.1_3572048_3572633_+	pfam14016, DUF4232, Protein of unknown function (DUF4232)	NA|297aa|up_8|NZ_CP023696.1_3572661_3573552_-	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|106aa|up_7|NZ_CP023696.1_3573815_3574133_+	NA	NA|106aa|up_6|NZ_CP023696.1_3574129_3574447_+	cd03469, Rieske_RO_Alpha_N, Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms	NA|138aa|up_5|NZ_CP023696.1_3574632_3575046_-	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme	NA|870aa|up_4|NZ_CP023696.1_3575174_3577784_+	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB	NA|196aa|up_3|NZ_CP023696.1_3578025_3578613_+	pfam10722, YbjN, Putative bacterial sensory transduction regulator	NA|394aa|up_2|NZ_CP023696.1_3578793_3579975_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|77aa|up_1|NZ_CP023696.1_3580199_3580430_+	COG4278, COG4278, Uncharacterized conserved protein [Function unknown]	NA|95aa|up_0|NZ_CP023696.1_3580484_3580769_+	NA	NA|180aa|down_0|NZ_CP023696.1_3581327_3581867_+	pfam10936, DUF2617, Protein of unknown function DUF2617	NA|562aa|down_1|NZ_CP023696.1_3581898_3583584_+	PRK03612, PRK03612, polyamine aminopropyltransferase	NA|386aa|down_2|NZ_CP023696.1_3583638_3584796_+	cd07823, SRPBCC_5, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|274aa|down_3|NZ_CP023696.1_3584813_3585635_+	cd09021, Aldose_epim_Ec_YphB, aldose 1-epimerase, similar to Escherichia coli YphB	NA|183aa|down_4|NZ_CP023696.1_3585644_3586193_+	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated	NA|341aa|down_5|NZ_CP023696.1_3586393_3587416_+	PRK09197, PRK09197, fructose-bisphosphate aldolase; Provisional	NA|390aa|down_6|NZ_CP023696.1_3587652_3588822_+	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]	NA|140aa|down_7|NZ_CP023696.1_3588895_3589315_-	pfam11349, DUF3151, Protein of unknown function (DUF3151)	NA|95aa|down_8|NZ_CP023696.1_3589353_3589638_-	NA	NA|304aa|down_9|NZ_CP023696.1_3590041_3590953_+	pfam11350, DUF3152, Protein of unknown function (DUF3152)
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	11	3801020-3801114	11	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CCGGGCGGGCGATTCCGAGCCGGG	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|203aa|up_9|NZ_CP023696.1_3787373_3787982_-,NA|262aa|down_3|NZ_CP023696.1_3806385_3807171_-,NA|172aa|down_9|NZ_CP023696.1_3814544_3815060_+	NA|203aa|up_9|NZ_CP023696.1_3787373_3787982_-	NA	NA|842aa|up_8|NZ_CP023696.1_3788412_3790938_+	CHL00095, clpC, Clp protease ATP binding subunit	NA|543aa|up_7|NZ_CP023696.1_3791232_3792861_-	pfam02113, Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family	NA|239aa|up_6|NZ_CP023696.1_3793304_3794021_+	pfam01551, Peptidase_M23, Peptidase family M23	NA|443aa|up_5|NZ_CP023696.1_3794046_3795375_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|236aa|up_4|NZ_CP023696.1_3795380_3796088_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|234aa|up_3|NZ_CP023696.1_3796123_3796825_-	PRK09111, PRK09111, DNA polymerase III subunits gamma and tau; Validated	NA|320aa|up_2|NZ_CP023696.1_3798024_3798984_-	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair]	NA|231aa|up_1|NZ_CP023696.1_3799253_3799946_-	pfam01569, PAP2, PAP2 superfamily	NA|295aa|up_0|NZ_CP023696.1_3800115_3801000_+	PHA00370, III, attachment protein	NA|374aa|down_0|NZ_CP023696.1_3801159_3802281_-	PRK13482, PRK13482, DNA integrity scanning protein DisA; Provisional	NA|468aa|down_1|NZ_CP023696.1_3802653_3804057_-	PRK11823, PRK11823, DNA repair protein RadA; Provisional	NA|686aa|down_2|NZ_CP023696.1_3804280_3806338_+	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|262aa|down_3|NZ_CP023696.1_3806385_3807171_-	NA	NA|310aa|down_4|NZ_CP023696.1_3807436_3808366_+	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]	NA|277aa|down_5|NZ_CP023696.1_3808401_3809232_+	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|618aa|down_6|NZ_CP023696.1_3809489_3811343_+	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional	NA|823aa|down_7|NZ_CP023696.1_3811520_3813989_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|88aa|down_8|NZ_CP023696.1_3814150_3814414_+	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown]	NA|172aa|down_9|NZ_CP023696.1_3814544_3815060_+	NA
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	12	4022447-4022620	1	CRT	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GCGGTGCGGTNGNCGTGCGGTGN	23	1	5	4022580-4022598|4022580-4022598|4022580-4022598|4022580-4022598|4022580-4022598	NZ_CP023696.1_2711254-2711272|NZ_CP023696.1_4920163-4920145|NZ_CP023696.1_2963967-2963985|NZ_CP023696.1_3832893-3832911|NZ_CP023696.1_5011836-5011854	NA	3	3	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|88aa|up_5|NZ_CP023696.1_4015693_4015957_-,NA|78aa|up_4|NZ_CP023696.1_4015943_4016177_-,NA|482aa|up_2|NZ_CP023696.1_4017547_4018993_-,NA|239aa|up_1|NZ_CP023696.1_4019446_4020163_-,NA|369aa|up_0|NZ_CP023696.1_4020166_4021273_-,NA|124aa|down_4|NZ_CP023696.1_4027699_4028071_-,NA|97aa|down_5|NZ_CP023696.1_4028136_4028427_-,NA|199aa|down_6|NZ_CP023696.1_4028521_4029118_-,NA|136aa|down_7|NZ_CP023696.1_4029289_4029697_-,NA|81aa|down_8|NZ_CP023696.1_4030105_4030348_+,NA|66aa|down_9|NZ_CP023696.1_4030605_4030803_-	NA|177aa|up_9|NZ_CP023696.1_4006533_4007064_+	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed	NA|128aa|up_8|NZ_CP023696.1_4007175_4007559_+	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed	NA|1162aa|up_7|NZ_CP023696.1_4008069_4011555_+	PRK00405, rpoB, DNA-directed RNA polymerase subunit beta; Reviewed	NA|1299aa|up_6|NZ_CP023696.1_4011651_4015548_+	PRK00566, PRK00566, DNA-directed RNA polymerase subunit beta'; Provisional	NA|88aa|up_5|NZ_CP023696.1_4015693_4015957_-	NA	NA|78aa|up_4|NZ_CP023696.1_4015943_4016177_-	NA	NA|304aa|up_3|NZ_CP023696.1_4016450_4017362_-	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase	NA|482aa|up_2|NZ_CP023696.1_4017547_4018993_-	NA	NA|239aa|up_1|NZ_CP023696.1_4019446_4020163_-	NA	NA|369aa|up_0|NZ_CP023696.1_4020166_4021273_-	NA	NA|312aa|down_0|NZ_CP023696.1_4022720_4023656_-	pfam05709, Sipho_tail, Phage tail protein	NA|432aa|down_1|NZ_CP023696.1_4023768_4025064_-	COG5412, COG5412, Phage-related protein [Function unknown]	NA|400aa|down_2|NZ_CP023696.1_4025060_4026260_-	COG5412, COG5412, Phage-related protein [Function unknown]	NA|129aa|down_3|NZ_CP023696.1_4027320_4027707_+	pfam12158, DUF3592, Protein of unknown function (DUF3592)	NA|124aa|down_4|NZ_CP023696.1_4027699_4028071_-	NA	NA|97aa|down_5|NZ_CP023696.1_4028136_4028427_-	NA	NA|199aa|down_6|NZ_CP023696.1_4028521_4029118_-	NA	NA|136aa|down_7|NZ_CP023696.1_4029289_4029697_-	NA	NA|81aa|down_8|NZ_CP023696.1_4030105_4030348_+	NA	NA|66aa|down_9|NZ_CP023696.1_4030605_4030803_-	NA
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	13	4294059-4294156	12	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CGCCTCAGCGGGGCCCGCCCGCGC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA|108aa|down_3|NZ_CP023696.1_4298904_4299228_+,NA|189aa|down_6|NZ_CP023696.1_4300854_4301421_-	NA|242aa|up_9|NZ_CP023696.1_4283449_4284175_-	COG4683, COG4683, Uncharacterized protein conserved in bacteria [Function unknown]	NA|350aa|up_8|NZ_CP023696.1_4284246_4285296_+	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea	NA|540aa|up_7|NZ_CP023696.1_4285605_4287225_+	COG3845, COG3845, ABC-type uncharacterized transport systems, ATPase components [General function prediction only]	NA|370aa|up_6|NZ_CP023696.1_4287221_4288331_+	COG4603, COG4603, ABC-type uncharacterized transport system, permease component [General function prediction only]	NA|424aa|up_5|NZ_CP023696.1_4288327_4289599_+	COG1079, COG1079, Uncharacterized ABC-type transport system, permease component [General function prediction only]	NA|135aa|up_4|NZ_CP023696.1_4289595_4290000_+	PRK05578, PRK05578, cytidine deaminase; Validated	NA|426aa|up_3|NZ_CP023696.1_4290255_4291533_+	PRK05820, deoA, thymidine phosphorylase; Reviewed	NA|120aa|up_2|NZ_CP023696.1_4291617_4291977_+	pfam13466, STAS_2, STAS domain	NA|355aa|up_1|NZ_CP023696.1_4291909_4292974_-	PRK08241, PRK08241, RNA polymerase subunit sigma-70	NA|237aa|up_0|NZ_CP023696.1_4293053_4293764_-	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD	NA|321aa|down_0|NZ_CP023696.1_4295513_4296476_+	cd08434, PBP2_GltC_like, The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold	NA|258aa|down_1|NZ_CP023696.1_4296705_4297479_-	COG0400, COG0400, Predicted esterase [General function prediction only]	NA|386aa|down_2|NZ_CP023696.1_4297612_4298770_+	PRK09358, PRK09358, adenosine deaminase; Provisional	NA|108aa|down_3|NZ_CP023696.1_4298904_4299228_+	NA	NA|67aa|down_4|NZ_CP023696.1_4299364_4299565_-	pfam04024, PspC, PspC domain	NA|198aa|down_5|NZ_CP023696.1_4299654_4300248_-	pfam04892, VanZ, VanZ like family	NA|189aa|down_6|NZ_CP023696.1_4300854_4301421_-	NA	NA|539aa|down_7|NZ_CP023696.1_4301530_4303147_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|232aa|down_8|NZ_CP023696.1_4303185_4303881_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|243aa|down_9|NZ_CP023696.1_4304053_4304782_+	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	14	4936184-4936246	13	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GGGCGTCCTGGCCGTAGCCCTGG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA|63aa|down_0|NZ_CP023696.1_4940357_4940546_+,NA|76aa|down_7|NZ_CP023696.1_4948494_4948722_+,NA|68aa|down_9|NZ_CP023696.1_4950263_4950467_-	NA|203aa|up_9|NZ_CP023696.1_4925719_4926328_-	pfam04264, YceI, YceI-like domain	NA|528aa|up_8|NZ_CP023696.1_4926837_4928421_+	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]	NA|66aa|up_7|NZ_CP023696.1_4928449_4928647_+	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit	NA|194aa|up_6|NZ_CP023696.1_4928858_4929440_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|184aa|up_5|NZ_CP023696.1_4929420_4929972_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|138aa|up_4|NZ_CP023696.1_4930068_4930482_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|1145aa|up_3|NZ_CP023696.1_4930492_4933927_-	pfam08376, NIT, Nitrate and nitrite sensing	NA|197aa|up_2|NZ_CP023696.1_4934317_4934908_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|137aa|up_1|NZ_CP023696.1_4934888_4935299_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|138aa|up_0|NZ_CP023696.1_4935435_4935849_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|63aa|down_0|NZ_CP023696.1_4940357_4940546_+	NA	NA|263aa|down_1|NZ_CP023696.1_4940961_4941750_+	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]	NA|495aa|down_2|NZ_CP023696.1_4941742_4943227_+	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed	NA|240aa|down_3|NZ_CP023696.1_4943686_4944406_+	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only]	NA|239aa|down_4|NZ_CP023696.1_4945172_4945889_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|477aa|down_5|NZ_CP023696.1_4946076_4947507_+	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit	NA|198aa|down_6|NZ_CP023696.1_4947513_4948107_+	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit	NA|76aa|down_7|NZ_CP023696.1_4948494_4948722_+	NA	NA|225aa|down_8|NZ_CP023696.1_4948865_4949540_+	cd13836, IHF_B, Beta subunit of integration host factor (IHFB)	NA|68aa|down_9|NZ_CP023696.1_4950263_4950467_-	NA
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	15	4936421-4936566	14	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GGGCGTCCTGGCCGTAGCCCTGG	23	1	1	4936444-4936459	NZ_CP023696.1_4936561-4936576	NA	3	3	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA|63aa|down_0|NZ_CP023696.1_4940357_4940546_+,NA|76aa|down_7|NZ_CP023696.1_4948494_4948722_+,NA|68aa|down_9|NZ_CP023696.1_4950263_4950467_-	NA|203aa|up_9|NZ_CP023696.1_4925719_4926328_-	pfam04264, YceI, YceI-like domain	NA|528aa|up_8|NZ_CP023696.1_4926837_4928421_+	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]	NA|66aa|up_7|NZ_CP023696.1_4928449_4928647_+	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit	NA|194aa|up_6|NZ_CP023696.1_4928858_4929440_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|184aa|up_5|NZ_CP023696.1_4929420_4929972_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|138aa|up_4|NZ_CP023696.1_4930068_4930482_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|1145aa|up_3|NZ_CP023696.1_4930492_4933927_-	pfam08376, NIT, Nitrate and nitrite sensing	NA|197aa|up_2|NZ_CP023696.1_4934317_4934908_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|137aa|up_1|NZ_CP023696.1_4934888_4935299_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|138aa|up_0|NZ_CP023696.1_4935435_4935849_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|63aa|down_0|NZ_CP023696.1_4940357_4940546_+	NA	NA|263aa|down_1|NZ_CP023696.1_4940961_4941750_+	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]	NA|495aa|down_2|NZ_CP023696.1_4941742_4943227_+	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed	NA|240aa|down_3|NZ_CP023696.1_4943686_4944406_+	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only]	NA|239aa|down_4|NZ_CP023696.1_4945172_4945889_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|477aa|down_5|NZ_CP023696.1_4946076_4947507_+	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit	NA|198aa|down_6|NZ_CP023696.1_4947513_4948107_+	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit	NA|76aa|down_7|NZ_CP023696.1_4948494_4948722_+	NA	NA|225aa|down_8|NZ_CP023696.1_4948865_4949540_+	cd13836, IHF_B, Beta subunit of integration host factor (IHFB)	NA|68aa|down_9|NZ_CP023696.1_4950263_4950467_-	NA
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	16	5086536-5086697	15	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	TCGCCGTGCCGGACTTCGCCGTGCCGG	27	2	2	5086563-5086580|5086653-5086670	NZ_CP023696.1_5637672-5637689|NZ_CP023696.1_6643924-6643941	NA	3	3	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|96aa|up_0|NZ_CP023696.1_5083346_5083634_+,NA|240aa|down_3|NZ_CP023696.1_5094818_5095538_-	NA|139aa|up_9|NZ_CP023696.1_5074911_5075328_-	pfam14530, DUF4439, Domain of unknown function (DUF4439)	NA|212aa|up_8|NZ_CP023696.1_5075324_5075960_-	PRK09111, PRK09111, DNA polymerase III subunits gamma and tau; Validated	NA|167aa|up_7|NZ_CP023696.1_5076249_5076750_+	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed	NA|334aa|up_6|NZ_CP023696.1_5076752_5077754_+	PRK12327, nusA, transcription elongation factor NusA; Provisional	NA|93aa|up_5|NZ_CP023696.1_5077938_5078217_+	pfam04296, DUF448, Protein of unknown function (DUF448)	NA|1022aa|up_4|NZ_CP023696.1_5078370_5081436_+	PRK05306, infB, translation initiation factor IF-2; Validated	NA|99aa|up_3|NZ_CP023696.1_5081595_5081892_+	pfam04456, DUF503, Protein of unknown function (DUF503)	NA|155aa|up_2|NZ_CP023696.1_5081919_5082384_+	PRK00521, rbfA, 30S ribosome-binding factor RbfA	NA|310aa|up_1|NZ_CP023696.1_5082383_5083313_+	PRK03287, truB, tRNA pseudouridine synthase B; Provisional	NA|96aa|up_0|NZ_CP023696.1_5083346_5083634_+	NA	NA|318aa|down_0|NZ_CP023696.1_5089218_5090172_+	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase	NA|1145aa|down_1|NZ_CP023696.1_5090432_5093867_-	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|78aa|down_2|NZ_CP023696.1_5094335_5094569_-	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|240aa|down_3|NZ_CP023696.1_5094818_5095538_-	NA	NA|396aa|down_4|NZ_CP023696.1_5095534_5096722_-	TIGR03923, T7SS_EccE, type VII secretion protein EccE	NA|511aa|down_5|NZ_CP023696.1_5097076_5098609_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|423aa|down_6|NZ_CP023696.1_5098626_5099895_+	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin	NA|569aa|down_7|NZ_CP023696.1_5100520_5102227_+	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|419aa|down_8|NZ_CP023696.1_5102254_5103511_+	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin	NA|120aa|down_9|NZ_CP023696.1_5103586_5103946_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	17	5478980-5479205	16	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CCCGCGCCCGTATCCGTACCCGCGCCCG	28	2	6	5479008-5479027|5479158-5479177|5479158-5479177|5479158-5479177|5479158-5479177|5479158-5479177	NZ_CP023696.1_4110872-4110891|NZ_CP023696.1_213742-213761|NZ_CP023696.1_302008-301989|NZ_CP023696.1_392260-392241|NZ_CP023696.1_960100-960119|NZ_CP023696.1_5528743-5528762	NA	4	4	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|173aa|up_9|NZ_CP023696.1_5468627_5469146_+,NA|76aa|down_1|NZ_CP023696.1_5481812_5482040_+,NA|140aa|down_2|NZ_CP023696.1_5482124_5482544_+,NA|305aa|down_3|NZ_CP023696.1_5482549_5483464_+,NA|508aa|down_4|NZ_CP023696.1_5484017_5485541_+,NA|112aa|down_6|NZ_CP023696.1_5486892_5487228_+	NA|173aa|up_9|NZ_CP023696.1_5468627_5469146_+	NA	NA|463aa|up_8|NZ_CP023696.1_5469506_5470895_+	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain	NA|198aa|up_7|NZ_CP023696.1_5471018_5471612_+	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein	NA|89aa|up_6|NZ_CP023696.1_5471914_5472181_+	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156	NA|247aa|up_5|NZ_CP023696.1_5472221_5472962_-	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]	NA|190aa|up_4|NZ_CP023696.1_5473241_5473811_+	pfam13305, WHG, WHG domain	NA|393aa|up_3|NZ_CP023696.1_5473852_5475031_+	cd01844, SGNH_hydrolase_like_6, SGNH_hydrolase subfamily	NA|135aa|up_2|NZ_CP023696.1_5475410_5475815_+	cd14797, DUF302, Uncharacterized domain family DUF302	NA|237aa|up_1|NZ_CP023696.1_5475858_5476569_-	pfam08237, PE-PPE, PE-PPE domain	NA|668aa|up_0|NZ_CP023696.1_5476884_5478888_-	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms]	NA|370aa|down_0|NZ_CP023696.1_5479857_5480967_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|76aa|down_1|NZ_CP023696.1_5481812_5482040_+	NA	NA|140aa|down_2|NZ_CP023696.1_5482124_5482544_+	NA	NA|305aa|down_3|NZ_CP023696.1_5482549_5483464_+	NA	NA|508aa|down_4|NZ_CP023696.1_5484017_5485541_+	NA	NA|415aa|down_5|NZ_CP023696.1_5485547_5486792_+	cd06164, S2P-M50_SpoIVFB_CBS, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation	NA|112aa|down_6|NZ_CP023696.1_5486892_5487228_+	NA	NA|432aa|down_7|NZ_CP023696.1_5487289_5488585_-	COG4247, Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) [Lipid metabolism]	NA|57aa|down_8|NZ_CP023696.1_5488835_5489006_+	PRK01110, rpmF, 50S ribosomal protein L32; Validated	NA|389aa|down_9|NZ_CP023696.1_5489095_5490262_+	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only]
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	18	5637367-5637452	17	CRISPRCasFinder	no	csa3	csa3,DEDDh,WYL,cas4,cas3,DinG	Type I-A	GGGACCACCCCCGCGTGCGCGGGGA	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA	NA|201aa|up_9|NZ_CP023696.1_5625598_5626201_+	cd01026, TOPRIM_OLD, TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family	NA|389aa|up_8|NZ_CP023696.1_5626420_5627587_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|453aa|up_7|NZ_CP023696.1_5627804_5629163_-	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase	NA|163aa|up_6|NZ_CP023696.1_5629385_5629874_+	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]	NA|354aa|up_5|NZ_CP023696.1_5630193_5631255_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|368aa|up_4|NZ_CP023696.1_5631331_5632435_-	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein	csa3|103aa|up_3|NZ_CP023696.1_5632431_5632740_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|135aa|up_2|NZ_CP023696.1_5632826_5633231_+	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family	NA|323aa|up_1|NZ_CP023696.1_5633628_5634597_+	pfam00161, RIP, Ribosome inactivating protein	NA|785aa|up_0|NZ_CP023696.1_5634695_5637050_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|510aa|down_0|NZ_CP023696.1_5637755_5639285_-	cd01555, UdpNAET, UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall	NA|906aa|down_1|NZ_CP023696.1_5639966_5642684_+	PRK09277, PRK09277, aconitate hydratase AcnA	NA|502aa|down_2|NZ_CP023696.1_5643300_5644806_+	TIGR03851, chitin_NgcE, carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein	NA|308aa|down_3|NZ_CP023696.1_5645037_5645961_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|275aa|down_4|NZ_CP023696.1_5646167_5646992_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|404aa|down_5|NZ_CP023696.1_5647206_5648418_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|350aa|down_6|NZ_CP023696.1_5648586_5649636_+	cd19995, PBP1_ABC_xylose_binding-like, periplasmic xylose-like sugar-binding component of the ABC-type transport systems	NA|265aa|down_7|NZ_CP023696.1_5650370_5651165_+	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]	NA|447aa|down_8|NZ_CP023696.1_5651161_5652502_+	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism]	NA|514aa|down_9|NZ_CP023696.1_5654975_5656517_+	TIGR00909, putative_amino_acid_transporter, amino acid transporter
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	19	5815368-5815485	18	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	TTCGGCTCGTTGCGCCTCCGGGCGCTGTGAGCGGGTCCCGG	41	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA|93aa|down_6|NZ_CP023696.1_5824219_5824498_+,NA|119aa|down_7|NZ_CP023696.1_5824505_5824862_+	NA|333aa|up_9|NZ_CP023696.1_5799766_5800765_+	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]	NA|714aa|up_8|NZ_CP023696.1_5800872_5803014_+	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]	NA|310aa|up_7|NZ_CP023696.1_5803189_5804119_+	PRK00971, PRK00971, glutaminase; Provisional	NA|698aa|up_6|NZ_CP023696.1_5804087_5806181_-	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only]	NA|133aa|up_5|NZ_CP023696.1_5806529_5806928_-	COG1846, MarR, Transcriptional regulators [Transcription]	NA|513aa|up_4|NZ_CP023696.1_5807526_5809065_+	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2	NA|696aa|up_3|NZ_CP023696.1_5809224_5811312_-	PRK10577, PRK10577, Fe(3+)-hydroxamate ABC transporter permease FhuB	NA|353aa|up_2|NZ_CP023696.1_5811308_5812367_-	cd01146, FhuD, Fe3+-siderophore binding domain FhuD	NA|268aa|up_1|NZ_CP023696.1_5812699_5813503_-	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]	NA|616aa|up_0|NZ_CP023696.1_5813499_5815347_-	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|421aa|down_0|NZ_CP023696.1_5815527_5816790_-	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters	NA|220aa|down_1|NZ_CP023696.1_5816786_5817446_-	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain	NA|594aa|down_2|NZ_CP023696.1_5817331_5819113_-	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|474aa|down_3|NZ_CP023696.1_5819109_5820531_-	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|537aa|down_4|NZ_CP023696.1_5820527_5822138_-	cd06450, DOPA_deC_like, DOPA decarboxylase family	NA|447aa|down_5|NZ_CP023696.1_5822455_5823796_-	PRK06938, PRK06938, diaminobutyrate--2-oxoglutarate aminotransferase; Provisional	NA|93aa|down_6|NZ_CP023696.1_5824219_5824498_+	NA	NA|119aa|down_7|NZ_CP023696.1_5824505_5824862_+	NA	NA|794aa|down_8|NZ_CP023696.1_5825044_5827426_-	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]	NA|318aa|down_9|NZ_CP023696.1_5828823_5829777_-	PRK15442, PRK15442, beta-lactamase TEM; Provisional
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	20	6012212-6012280	19	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GCCGGGGCGGCCGGGACCGGCGGG	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|171aa|up_2|NZ_CP023696.1_6009275_6009788_+,NA	NA|595aa|up_9|NZ_CP023696.1_6002077_6003862_-	PRK07819, PRK07819, 3-hydroxybutyryl-CoA dehydrogenase; Validated	NA|192aa|up_8|NZ_CP023696.1_6004285_6004861_+	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion]	NA|172aa|up_7|NZ_CP023696.1_6005149_6005665_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|138aa|up_6|NZ_CP023696.1_6005661_6006075_-	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis]	NA|531aa|up_5|NZ_CP023696.1_6006127_6007720_-	pfam08386, Abhydrolase_4, TAP-like protein	NA|149aa|up_4|NZ_CP023696.1_6007900_6008347_+	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport	NA|188aa|up_3|NZ_CP023696.1_6008575_6009139_-	cd12108, Hr-like, Hemerythrin-like domain	NA|171aa|up_2|NZ_CP023696.1_6009275_6009788_+	NA	NA|392aa|up_1|NZ_CP023696.1_6009952_6011128_-	PRK09257, PRK09257, aromatic amino acid transaminase	NA|296aa|up_0|NZ_CP023696.1_6011120_6012008_-	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]	NA|155aa|down_0|NZ_CP023696.1_6012372_6012837_+	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|278aa|down_1|NZ_CP023696.1_6013058_6013892_+	cd08663, DAP_dppA_1, Peptidase M55, D-aminopeptidase dipeptide-binding protein family	NA|463aa|down_2|NZ_CP023696.1_6013884_6015273_+	PRK07906, PRK07906, hypothetical protein; Provisional	NA|664aa|down_3|NZ_CP023696.1_6015293_6017285_+	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]	NA|312aa|down_4|NZ_CP023696.1_6017527_6018463_+	cd07025, Peptidase_S66, LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein	NA|364aa|down_5|NZ_CP023696.1_6018535_6019627_-	PRK09358, PRK09358, adenosine deaminase; Provisional	NA|247aa|down_6|NZ_CP023696.1_6019971_6020712_-	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|193aa|down_7|NZ_CP023696.1_6020846_6021425_+	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]	NA|125aa|down_8|NZ_CP023696.1_6021563_6021938_-	cd06587, VOC, vicinal oxygen chelate (VOC) family	NA|268aa|down_9|NZ_CP023696.1_6021962_6022766_-	PRK08317, PRK08317, hypothetical protein; Provisional
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	21	6130899-6131008	20	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	GCGCGAGTGGACCCGGAGGGGCGCG	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA,NA	NA|198aa|up_9|NZ_CP023696.1_6120946_6121540_-	PRK03759, PRK03759, isopentenyl-diphosphate Delta-isomerase	NA|180aa|up_8|NZ_CP023696.1_6121726_6122266_-	COG3153, COG3153, Predicted acetyltransferase [General function prediction only]	NA|314aa|up_7|NZ_CP023696.1_6122262_6123204_-	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]	NA|654aa|up_6|NZ_CP023696.1_6123582_6125544_+	pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase	NA|246aa|up_5|NZ_CP023696.1_6125540_6126278_+	cd02523, PC_cytidylyltransferase, Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline	NA|354aa|up_4|NZ_CP023696.1_6126265_6127327_+	cd08174, G1PDH-like, Glycerol-1-phosphate dehydrogenase-like	NA|260aa|up_3|NZ_CP023696.1_6127304_6128084_+	pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase	NA|291aa|up_2|NZ_CP023696.1_6128089_6128962_+	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only]	NA|310aa|up_1|NZ_CP023696.1_6129069_6129999_+	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]	NA|263aa|up_0|NZ_CP023696.1_6130003_6130792_+	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system	NA|314aa|down_0|NZ_CP023696.1_6131274_6132216_+	TIGR03464, HpnC, squalene synthase HpnC	NA|317aa|down_1|NZ_CP023696.1_6132212_6133163_+	TIGR03465, HpnD, squalene synthase HpnD	NA|458aa|down_2|NZ_CP023696.1_6133200_6134574_+	TIGR03467, HpnE, squalene-associated FAD-dependent desaturase	NA|353aa|down_3|NZ_CP023696.1_6134612_6135671_+	cd00685, Trans_IPPS_HT, Trans-Isoprenyl Diphosphate Synthases, head-to-tail	NA|709aa|down_4|NZ_CP023696.1_6135845_6137972_+	cd02892, SQCY_1, Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold	NA|216aa|down_5|NZ_CP023696.1_6138389_6139037_+	cd17877, NP_MTAN-like, nucleoside phosphorylases similar to 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases	NA|354aa|down_6|NZ_CP023696.1_6139003_6140065_+	TIGR03470, HpnH, hopanoid biosynthesis associated radical SAM protein HpnH	NA|462aa|down_7|NZ_CP023696.1_6140078_6141464_+	cd00610, OAT_like, Acetyl ornithine aminotransferase family	NA|204aa|down_8|NZ_CP023696.1_6141522_6142134_+	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain	NA|271aa|down_9|NZ_CP023696.1_6142357_6143170_-	pfam13350, Y_phosphatase3, Tyrosine phosphatase family
GCF_008704425.1_ASM870442v1	NZ_CP023696	Streptomyces fradiae ATCC 10745 = DSM 40063 strain ATCC 10745 chromosome, complete genome	22	6284689-6284950	2	CRT	no		csa3,DEDDh,WYL,cas4,cas3,DinG	Orphan	CNNGGCCGTACCGGCCGCA	19	0	0	NA	NA	NA	5	5	Orphan	csa3,DEDDh,WYL,cas4,cas3,DinG	NA|92aa|up_8|NZ_CP023696.1_6273417_6273693_-,NA|146aa|up_2|NZ_CP023696.1_6278868_6279306_-,NA	NA|353aa|up_9|NZ_CP023696.1_6271948_6273007_-	cd08230, glucose_DH, Glucose dehydrogenase	NA|92aa|up_8|NZ_CP023696.1_6273417_6273693_-	NA	NA|136aa|up_7|NZ_CP023696.1_6273689_6274097_-	pfam07784, DUF1622, Protein of unknown function (DUF1622)	NA|190aa|up_6|NZ_CP023696.1_6274274_6274844_-	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism]	NA|288aa|up_5|NZ_CP023696.1_6275070_6275934_+	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism]	NA|420aa|up_4|NZ_CP023696.1_6276392_6277652_+	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily	NA|348aa|up_3|NZ_CP023696.1_6277686_6278730_-	TIGR03718, R_switched_Alx, integral membrane protein, TerC family	NA|146aa|up_2|NZ_CP023696.1_6278868_6279306_-	NA	NA|106aa|up_1|NZ_CP023696.1_6279602_6279920_+	pfam12802, MarR_2, MarR family	NA|947aa|up_0|NZ_CP023696.1_6280095_6282936_-	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only]	NA|357aa|down_0|NZ_CP023696.1_6285118_6286189_+	cd08286, FDH_like_ADH2, formaldehyde dehydrogenase (FDH)-like	NA|606aa|down_1|NZ_CP023696.1_6286712_6288530_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|893aa|down_2|NZ_CP023696.1_6288626_6291305_-	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion]	NA|300aa|down_3|NZ_CP023696.1_6291552_6292452_+	pfam00582, Usp, Universal stress protein family	NA|181aa|down_4|NZ_CP023696.1_6292726_6293269_-	pfam12724, Flavodoxin_5, Flavodoxin domain	NA|223aa|down_5|NZ_CP023696.1_6293402_6294071_-	pfam14333, DUF4389, Domain of unknown function (DUF4389)	NA|339aa|down_6|NZ_CP023696.1_6294588_6295605_+	pfam00582, Usp, Universal stress protein family	NA|309aa|down_7|NZ_CP023696.1_6295601_6296528_+	pfam00582, Usp, Universal stress protein family	NA|69aa|down_8|NZ_CP023696.1_6296759_6296966_+	pfam08940, DUF1918, Domain of unknown function (DUF1918)	NA|215aa|down_9|NZ_CP023696.1_6297399_6298044_-	cd04586, CBS_pair_BON_assoc, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain
