assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	1	880477-880621	1	PILER-CR	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GGGTCGGTCAGGGCGTACGGGTCGGCGGGC	30	0	0	NA	NA	NA	2	2	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|252aa|up_9|NZ_CP029190.1_866658_867414_+,NA|167aa|up_8|NZ_CP029190.1_867517_868018_-,NA|169aa|up_3|NZ_CP029190.1_875935_876442_+,NA|382aa|down_4|NZ_CP029190.1_887304_888450_+,NA|64aa|down_6|NZ_CP029190.1_889808_890000_-	NA|252aa|up_9|NZ_CP029190.1_866658_867414_+	NA	NA|167aa|up_8|NZ_CP029190.1_867517_868018_-	NA	NA|221aa|up_7|NZ_CP029190.1_868414_869077_+	cd05829, Sortase_F, Sortase domain found in the class F family of sortases	NA|308aa|up_6|NZ_CP029190.1_869171_870095_-	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins	NA|397aa|up_5|NZ_CP029190.1_873723_874914_-	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap	NA|190aa|up_4|NZ_CP029190.1_875181_875751_+	PRK09645, PRK09645, ECF RNA polymerase sigma factor SigL	NA|169aa|up_3|NZ_CP029190.1_875935_876442_+	NA	NA|130aa|up_2|NZ_CP029190.1_876469_876859_-	pfam04341, DUF485, Protein of unknown function, DUF485	NA|293aa|up_1|NZ_CP029190.1_876876_877755_-	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]	NA|659aa|up_0|NZ_CP029190.1_878360_880337_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|481aa|down_0|NZ_CP029190.1_881915_883358_+	pfam06762, LMF1, Lipase maturation factor	NA|329aa|down_1|NZ_CP029190.1_883337_884324_-	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1	NA|179aa|down_2|NZ_CP029190.1_884946_885483_+	TIGR03276, Phn-HD, phosphonate degradation operons associated HDIG domain protein	NA|497aa|down_3|NZ_CP029190.1_885599_887090_-	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|382aa|down_4|NZ_CP029190.1_887304_888450_+	NA	NA|440aa|down_5|NZ_CP029190.1_888159_889479_-	pfam01551, Peptidase_M23, Peptidase family M23	NA|64aa|down_6|NZ_CP029190.1_889808_890000_-	NA	NA|140aa|down_7|NZ_CP029190.1_890062_890482_-	pfam02261, Asp_decarbox, Aspartate decarboxylase	NA|919aa|down_8|NZ_CP029190.1_890900_893657_-	COG3899, COG3899, Predicted ATPase [General function prediction only]	NA|431aa|down_9|NZ_CP029190.1_893655_894948_+	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	2	2427837-2428090	1	CRT	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GGCGCCGGCCAGGCCCGGCGGTACGGCCCCGCCGGTACGGGCG	43	1	1	2428026-2428047	NZ_CP029190.1_3105887-3105908	NA	3	3	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|175aa|up_9|NZ_CP029190.1_2417258_2417783_-,NA|214aa|up_8|NZ_CP029190.1_2417893_2418535_-,NA	NA|175aa|up_9|NZ_CP029190.1_2417258_2417783_-	NA	NA|214aa|up_8|NZ_CP029190.1_2417893_2418535_-	NA	NA|327aa|up_7|NZ_CP029190.1_2419125_2420106_-	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]	NA|209aa|up_6|NZ_CP029190.1_2420378_2421005_+	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|567aa|up_5|NZ_CP029190.1_2421431_2423132_-	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM	NA|112aa|up_4|NZ_CP029190.1_2423225_2423561_-	pfam12823, DUF3817, Domain of unknown function (DUF3817)	NA|170aa|up_3|NZ_CP029190.1_2423698_2424208_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|247aa|up_2|NZ_CP029190.1_2424377_2425118_-	pfam13350, Y_phosphatase3, Tyrosine phosphatase family	NA|371aa|up_1|NZ_CP029190.1_2425143_2426256_-	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]	NA|357aa|up_0|NZ_CP029190.1_2426670_2427741_+	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6	NA|211aa|down_0|NZ_CP029190.1_2428120_2428753_-	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|229aa|down_1|NZ_CP029190.1_2428749_2429436_-	pfam13761, DUF4166, Domain of unknown function (DUF4166)	NA|233aa|down_2|NZ_CP029190.1_2429432_2430131_-	TIGR02978, Phage_shock_protein_C	NA|99aa|down_3|NZ_CP029190.1_2430336_2430633_-	pfam01910, Thiamine_BP, Thiamine-binding protein	NA|120aa|down_4|NZ_CP029190.1_2430629_2430989_-	pfam12823, DUF3817, Domain of unknown function (DUF3817)	NA|213aa|down_5|NZ_CP029190.1_2431129_2431768_+	pfam01987, AIM24, Mitochondrial biogenesis AIM24	NA|217aa|down_6|NZ_CP029190.1_2431767_2432418_+	pfam01987, AIM24, Mitochondrial biogenesis AIM24	NA|271aa|down_7|NZ_CP029190.1_2432432_2433245_+	COG2013, COG2013, Uncharacterized conserved protein [Function unknown]	NA|159aa|down_8|NZ_CP029190.1_2433328_2433805_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|160aa|down_9|NZ_CP029190.1_2433906_2434386_-	pfam00720, SSI, Subtilisin inhibitor-like
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	3	2613159-2613243	1	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	CTTCGGCGCGACCGGCCACGGAGCC	25	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA,NA|233aa|down_3|NZ_CP029190.1_2616283_2616982_-	NA|400aa|up_9|NZ_CP029190.1_2580683_2581883_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|398aa|up_8|NZ_CP029190.1_2581980_2583174_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|73aa|up_7|NZ_CP029190.1_2583211_2583430_-	COG3251, COG3251, Uncharacterized protein conserved in bacteria [Function unknown]	NA|5448aa|up_6|NZ_CP029190.1_2583426_2599770_-	PRK12316, PRK12316, peptide synthase; Provisional	NA|1300aa|up_5|NZ_CP029190.1_2599853_2603753_-	cd05906, A_NRPS_TubE_like, The adenylation domain (A domain) of a family of nonribosomal peptide synthetases (NRPSs) synthesizing toxins and antitumor agents	NA|261aa|up_4|NZ_CP029190.1_2603749_2604532_-	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|254aa|up_3|NZ_CP029190.1_2604933_2605695_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|531aa|up_2|NZ_CP029190.1_2605741_2607334_-	pfam04820, Trp_halogenase, Tryptophan halogenase	NA|764aa|up_1|NZ_CP029190.1_2607617_2609909_+	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]	NA|986aa|up_0|NZ_CP029190.1_2609990_2612948_-	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|300aa|down_0|NZ_CP029190.1_2613608_2614508_+	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism]	NA|178aa|down_1|NZ_CP029190.1_2614619_2615153_+	smart00903, Flavin_Reduct, Flavin reductase like domain	NA|272aa|down_2|NZ_CP029190.1_2615370_2616186_-	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|233aa|down_3|NZ_CP029190.1_2616283_2616982_-	NA	NA|78aa|down_4|NZ_CP029190.1_2617010_2617244_-	COG3251, COG3251, Uncharacterized protein conserved in bacteria [Function unknown]	NA|373aa|down_5|NZ_CP029190.1_2617596_2618715_+	PRK03343, PRK03343, transaldolase; Validated	NA|722aa|down_6|NZ_CP029190.1_2618804_2620970_-	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]	NA|255aa|down_7|NZ_CP029190.1_2621032_2621797_-	PRK14968, PRK14968, putative methyltransferase; Provisional	NA|658aa|down_8|NZ_CP029190.1_2622092_2624066_+	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|251aa|down_9|NZ_CP029190.1_2626065_2626818_+	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism]
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	4	2873159-2873242	2	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	AGCTACAGCAGCAGCCAGGGCGAC	24	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|173aa|up_1|NZ_CP029190.1_2871772_2872291_+,NA|167aa|down_2|NZ_CP029190.1_2879531_2880032_-	NA|285aa|up_9|NZ_CP029190.1_2863522_2864377_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|760aa|up_8|NZ_CP029190.1_2864462_2866742_+	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	NA|355aa|up_7|NZ_CP029190.1_2866738_2867803_-	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|301aa|up_6|NZ_CP029190.1_2867922_2868825_+	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|131aa|up_5|NZ_CP029190.1_2868853_2869246_+	cd02226, cupin_YdbB-like, Bacillus subtilis YdbB and related proteins, cupin domain	NA|214aa|up_4|NZ_CP029190.1_2869289_2869931_-	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|301aa|up_3|NZ_CP029190.1_2870078_2870981_+	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]	NA|260aa|up_2|NZ_CP029190.1_2870973_2871753_+	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system	NA|173aa|up_1|NZ_CP029190.1_2871772_2872291_+	NA	NA|275aa|up_0|NZ_CP029190.1_2872301_2873126_+	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|1659aa|down_0|NZ_CP029190.1_2873427_2878404_-	pfam05088, Bac_GDH, Bacterial NAD-glutamate dehydrogenase	NA|242aa|down_1|NZ_CP029190.1_2878809_2879535_-	COG0546, Gph, Predicted phosphatases [General function prediction only]	NA|167aa|down_2|NZ_CP029190.1_2879531_2880032_-	NA	NA|933aa|down_3|NZ_CP029190.1_2881397_2884196_-	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed	NA|215aa|down_4|NZ_CP029190.1_2884423_2885068_+	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|391aa|down_5|NZ_CP029190.1_2885077_2886250_+	COG3214, COG3214, Uncharacterized protein conserved in bacteria [Function unknown]	NA|237aa|down_6|NZ_CP029190.1_2886290_2887001_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|289aa|down_7|NZ_CP029190.1_2887192_2888059_-	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site	NA|255aa|down_8|NZ_CP029190.1_2888234_2888999_-	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only]	NA|580aa|down_9|NZ_CP029190.1_2889074_2890814_-	PRK13613, PRK13613, lipoprotein LpqB; Provisional
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	5	3177761-3177877	3	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GCCGGGCTACCGCCGGAGCTGTGCGGGCCGGCGGCGGTGCCGGCG	45	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|257aa|up_8|NZ_CP029190.1_3165309_3166080_-,NA|174aa|up_7|NZ_CP029190.1_3166358_3166880_+,NA|81aa|up_5|NZ_CP029190.1_3167671_3167914_-,NA|294aa|up_4|NZ_CP029190.1_3167990_3168872_-,NA|285aa|down_4|NZ_CP029190.1_3183697_3184552_-	NA|511aa|up_9|NZ_CP029190.1_3161451_3162984_-	PTZ00121, PTZ00121, MAEBL; Provisional	NA|257aa|up_8|NZ_CP029190.1_3165309_3166080_-	NA	NA|174aa|up_7|NZ_CP029190.1_3166358_3166880_+	NA	NA|236aa|up_6|NZ_CP029190.1_3166898_3167606_-	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|81aa|up_5|NZ_CP029190.1_3167671_3167914_-	NA	NA|294aa|up_4|NZ_CP029190.1_3167990_3168872_-	NA	NA|408aa|up_3|NZ_CP029190.1_3169012_3170236_+	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap	NA|762aa|up_2|NZ_CP029190.1_3170370_3172656_+	pfam00672, HAMP, HAMP domain	NA|161aa|up_1|NZ_CP029190.1_3174314_3174797_+	pfam14102, Caps_synth_CapC, Capsule biosynthesis CapC	NA|360aa|up_0|NZ_CP029190.1_3174885_3175965_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|408aa|down_0|NZ_CP029190.1_3178107_3179331_-	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]	NA|254aa|down_1|NZ_CP029190.1_3181228_3181990_+	pfam05719, GPP34, Golgi phosphoprotein 3 (GPP34)	NA|294aa|down_2|NZ_CP029190.1_3182260_3183142_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|71aa|down_3|NZ_CP029190.1_3183363_3183576_+	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|285aa|down_4|NZ_CP029190.1_3183697_3184552_-	NA	NA|400aa|down_5|NZ_CP029190.1_3184670_3185870_+	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|261aa|down_6|NZ_CP029190.1_3185985_3186768_+	PRK07890, PRK07890, short chain dehydrogenase; Provisional	NA|861aa|down_7|NZ_CP029190.1_3186844_3189427_+	PRK09234, fbiC, FO synthase; Reviewed	NA|361aa|down_8|NZ_CP029190.1_3189446_3190529_-	pfam13350, Y_phosphatase3, Tyrosine phosphatase family	NA|371aa|down_9|NZ_CP029190.1_3190860_3191973_+	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	6	3326070-3326171	4	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GGCTCCGGACCGGACGCCGTCCGG	24	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA,NA	NA|231aa|up_9|NZ_CP029190.1_3314058_3314751_-	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription]	NA|252aa|up_8|NZ_CP029190.1_3314940_3315696_+	PRK02947, PRK02947, sugar isomerase domain-containing protein	NA|450aa|up_7|NZ_CP029190.1_3315707_3317057_-	cd00130, PAS, PAS domain; PAS motifs appear in archaea, eubacteria and eukarya	NA|208aa|up_6|NZ_CP029190.1_3317463_3318087_-	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase	NA|371aa|up_5|NZ_CP029190.1_3318325_3319438_+	PRK12350, PRK12350, citrate synthase 2; Provisional	NA|200aa|up_4|NZ_CP029190.1_3319509_3320109_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|249aa|up_3|NZ_CP029190.1_3320096_3320843_-	PRK07827, PRK07827, enoyl-CoA hydratase family protein	NA|387aa|up_2|NZ_CP029190.1_3320970_3322131_-	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|644aa|up_1|NZ_CP029190.1_3322127_3324059_-	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|533aa|up_0|NZ_CP029190.1_3324066_3325665_-	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain	NA|267aa|down_0|NZ_CP029190.1_3327616_3328417_-	TIGR03084, conserved_hypothetical_protein, TIGR03084 family protein	NA|174aa|down_1|NZ_CP029190.1_3328603_3329125_+	pfam08877, MepB, MepB protein	NA|325aa|down_2|NZ_CP029190.1_3329121_3330096_-	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism]	NA|885aa|down_3|NZ_CP029190.1_3330163_3332818_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|373aa|down_4|NZ_CP029190.1_3332974_3334093_+	TIGR01366, Putative_phosphoserine_aminotransferase_PSAT	NA|1135aa|down_5|NZ_CP029190.1_3334283_3337688_+	PRK14083, PRK14083, HSP90 family protein; Provisional	NA|818aa|down_6|NZ_CP029190.1_3337718_3340172_-	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7	NA|102aa|down_7|NZ_CP029190.1_3340232_3340538_-	pfam10745, DUF2530, Protein of unknown function (DUF2530)	NA|463aa|down_8|NZ_CP029190.1_3340755_3342144_+	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]	NA|61aa|down_9|NZ_CP029190.1_3342136_3342319_-	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	7	3517914-3518019	5	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	TTCCGACTCTATCAGATCTTTTCGG	25	1	3	3517939-3517994|3517939-3517994|3517939-3517994	NZ_CP029190.1_2079168-2079223|NZ_CP029190.1_6283534-6283479|NZ_CP029190.1_2905063-2905118	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|206aa|up_8|NZ_CP029190.1_3503056_3503674_-,NA|103aa|up_7|NZ_CP029190.1_3504073_3504382_+,NA|275aa|up_6|NZ_CP029190.1_3504484_3505309_+,NA|521aa|up_4|NZ_CP029190.1_3506608_3508171_+,NA|202aa|up_0|NZ_CP029190.1_3511888_3512494_+,NA	NA|283aa|up_9|NZ_CP029190.1_3502149_3502998_+	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]	NA|206aa|up_8|NZ_CP029190.1_3503056_3503674_-	NA	NA|103aa|up_7|NZ_CP029190.1_3504073_3504382_+	NA	NA|275aa|up_6|NZ_CP029190.1_3504484_3505309_+	NA	NA|410aa|up_5|NZ_CP029190.1_3505382_3506612_+	pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein	NA|521aa|up_4|NZ_CP029190.1_3506608_3508171_+	NA	NA|472aa|up_3|NZ_CP029190.1_3508188_3509604_+	pfam12846, AAA_10, AAA-like domain	NA|530aa|up_2|NZ_CP029190.1_3509605_3511195_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|186aa|up_1|NZ_CP029190.1_3511210_3511768_-	PRK10514, PRK10514, putative acetyltransferase; Provisional	NA|202aa|up_0|NZ_CP029190.1_3511888_3512494_+	NA	NA|179aa|down_0|NZ_CP029190.1_3518275_3518812_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|433aa|down_1|NZ_CP029190.1_3518917_3520216_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|564aa|down_2|NZ_CP029190.1_3520294_3521986_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|469aa|down_3|NZ_CP029190.1_3522128_3523535_-	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]	NA|264aa|down_4|NZ_CP029190.1_3523874_3524666_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|676aa|down_5|NZ_CP029190.1_3524930_3526958_+	pfam08305, NPCBM, NPCBM/NEW2 domain	NA|732aa|down_6|NZ_CP029190.1_3526980_3529176_-	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B	NA|543aa|down_7|NZ_CP029190.1_3529807_3531436_+	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional	NA|399aa|down_8|NZ_CP029190.1_3531517_3532714_+	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase	NA|277aa|down_9|NZ_CP029190.1_3532787_3533618_+	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	8	4144060-4144165	6	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	CCGAAAGGATCTGATAGAGTCGGAA	25	1	3	4144085-4144140|4144085-4144140|4144085-4144140	NZ_CP029190.1_2079223-2079168|NZ_CP029190.1_6283479-6283534|NZ_CP029190.1_2905118-2905063	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|173aa|up_4|NZ_CP029190.1_4139411_4139930_+,NA|33aa|down_6|NZ_CP029190.1_4154715_4154814_+	NA|279aa|up_9|NZ_CP029190.1_4133095_4133932_+	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|225aa|up_8|NZ_CP029190.1_4133928_4134603_+	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain	NA|617aa|up_7|NZ_CP029190.1_4134809_4136660_+	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional	NA|729aa|up_6|NZ_CP029190.1_4136744_4138931_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|114aa|up_5|NZ_CP029190.1_4139036_4139378_+	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown]	NA|173aa|up_4|NZ_CP029190.1_4139411_4139930_+	NA	NA|277aa|up_3|NZ_CP029190.1_4140012_4140843_+	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|250aa|up_2|NZ_CP029190.1_4140839_4141589_+	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|270aa|up_1|NZ_CP029190.1_4141676_4142486_+	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed	NA|332aa|up_0|NZ_CP029190.1_4142547_4143543_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|199aa|down_0|NZ_CP029190.1_4149632_4150229_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|221aa|down_1|NZ_CP029190.1_4150302_4150965_+	cd07526, HAD_BPGM_like, subfamily of beta-phosphoglucomutase-like family, similar to Escherichia coli 6-phosphogluconate phosphatase YieH	NA|402aa|down_2|NZ_CP029190.1_4151010_4152216_+	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters	NA|390aa|down_3|NZ_CP029190.1_4152166_4153336_+	cd09994, HDAC_AcuC_like, Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes	NA|272aa|down_4|NZ_CP029190.1_4153407_4154223_+	pfam15698, Phosphatase, Phosphatase	NA|78aa|down_5|NZ_CP029190.1_4154340_4154574_+	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family	NA|33aa|down_6|NZ_CP029190.1_4154715_4154814_+	NA	NA|359aa|down_7|NZ_CP029190.1_4154895_4155972_+	cd05240, UDP_G4E_3_SDR_e, UDP-glucose 4 epimerase (G4E), subgroup 3, extended (e) SDRs	NA|331aa|down_8|NZ_CP029190.1_4155971_4156964_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|407aa|down_9|NZ_CP029190.1_4157051_4158272_-	pfam05518, Totivirus_coat, Totivirus coat protein
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	9	4270909-4271004	7	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GCCCCGTCAGGGGCGCGGGGAACTGCGCG	29	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|200aa|up_2|NZ_CP029190.1_4267890_4268490_-,NA|141aa|down_5|NZ_CP029190.1_4277637_4278060_+	NA|452aa|up_9|NZ_CP029190.1_4259625_4260981_+	PRK06076, PRK06076, NADH-quinone oxidoreductase subunit NuoH	NA|203aa|up_8|NZ_CP029190.1_4260973_4261582_+	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI	NA|273aa|up_7|NZ_CP029190.1_4261578_4262397_+	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J	NA|100aa|up_6|NZ_CP029190.1_4262393_4262693_+	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK	NA|632aa|up_5|NZ_CP029190.1_4262704_4264600_+	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed	NA|527aa|up_4|NZ_CP029190.1_4264601_4266182_+	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed	NA|542aa|up_3|NZ_CP029190.1_4266178_4267804_+	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN	NA|200aa|up_2|NZ_CP029190.1_4267890_4268490_-	NA	NA|409aa|up_1|NZ_CP029190.1_4268676_4269903_-	PLN02856, PLN02856, fumarylacetoacetase	NA|283aa|up_0|NZ_CP029190.1_4270050_4270899_+	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase	NA|672aa|down_0|NZ_CP029190.1_4271124_4273140_-	COG2936, COG2936, Predicted acyl esterases [General function prediction only]	NA|495aa|down_1|NZ_CP029190.1_4273156_4274641_-	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism]	NA|337aa|down_2|NZ_CP029190.1_4274900_4275911_+	cd00685, Trans_IPPS_HT, Trans-Isoprenyl Diphosphate Synthases, head-to-tail	NA|401aa|down_3|NZ_CP029190.1_4276125_4277328_+	cd16327, RseB, RseB, a sensor in periplasmic stress	NA|90aa|down_4|NZ_CP029190.1_4277359_4277629_+	pfam09274, ParG, ParG	NA|141aa|down_5|NZ_CP029190.1_4277637_4278060_+	NA	NA|447aa|down_6|NZ_CP029190.1_4278049_4279390_-	cd03876, M28_SGAP_like, M28 Zn-peptidase Streptomyces griseus aminopeptidase and similar proteins	NA|316aa|down_7|NZ_CP029190.1_4279596_4280544_-	COG2962, RarD, Predicted permeases [General function prediction only]	NA|359aa|down_8|NZ_CP029190.1_4280747_4281824_-	PRK11867, PRK11867, 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed	NA|648aa|down_9|NZ_CP029190.1_4281816_4283760_-	TIGR03710, OAFO_sf, 2-oxoacid:acceptor oxidoreductase, alpha subunit
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	10	4562437-4562513	8	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GCGGATGCCCCGGCTCCGCCGGGCA	25	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|97aa|up_8|NZ_CP029190.1_4537658_4537949_-,NA|248aa|down_3|NZ_CP029190.1_4565990_4566734_-,NA|105aa|down_5|NZ_CP029190.1_4568519_4568834_-,NA|114aa|down_6|NZ_CP029190.1_4568942_4569284_+	NA|318aa|up_9|NZ_CP029190.1_4536624_4537578_+	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]	NA|97aa|up_8|NZ_CP029190.1_4537658_4537949_-	NA	NA|2233aa|up_7|NZ_CP029190.1_4537945_4544644_-	TIGR03696, tRNA_nuclease_WapA, RHS repeat-associated core domain	NA|1657aa|up_6|NZ_CP029190.1_4545111_4550082_+	COG5479, COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis [Cell envelope biogenesis, outer membrane]	NA|1672aa|up_5|NZ_CP029190.1_4550852_4555868_+	pfam08310, LGFP, LGFP repeat	NA|585aa|up_4|NZ_CP029190.1_4555943_4557698_-	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|208aa|up_3|NZ_CP029190.1_4558463_4559087_-	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|69aa|up_2|NZ_CP029190.1_4559378_4559585_-	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit	NA|533aa|up_1|NZ_CP029190.1_4559593_4561192_-	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]	NA|286aa|up_0|NZ_CP029190.1_4561323_4562181_+	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]	NA|386aa|down_0|NZ_CP029190.1_4562784_4563942_+	cd07302, CHD, cyclase homology domain	NA|272aa|down_1|NZ_CP029190.1_4563995_4564811_+	PRK07657, PRK07657, enoyl-CoA hydratase; Provisional	NA|371aa|down_2|NZ_CP029190.1_4564859_4565972_+	smart00267, GGDEF, diguanylate cyclase	NA|248aa|down_3|NZ_CP029190.1_4565990_4566734_-	NA	NA|514aa|down_4|NZ_CP029190.1_4566882_4568424_+	PRK09367, PRK09367, histidine ammonia-lyase; Provisional	NA|105aa|down_5|NZ_CP029190.1_4568519_4568834_-	NA	NA|114aa|down_6|NZ_CP029190.1_4568942_4569284_+	NA	NA|425aa|down_7|NZ_CP029190.1_4569415_4570690_+	pfam17964, Big_10, Bacterial Ig domain	NA|328aa|down_8|NZ_CP029190.1_4570798_4571782_+	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain	NA|280aa|down_9|NZ_CP029190.1_4571799_4572639_-	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only]
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	11	4790098-4790345	2	PILER-CR	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	CCGGGGTCTCGACCGCGGCGACGGCCTTGCGGGCCCGGGTGCGGCGCGGCTTGGCCGG	58	0	0	NA	NA	NA	2	2	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|261aa|up_7|NZ_CP029190.1_4782880_4783663_+,NA|171aa|up_6|NZ_CP029190.1_4783659_4784172_-,NA|217aa|up_3|NZ_CP029190.1_4786284_4786935_+,NA|98aa|down_1|NZ_CP029190.1_4793227_4793521_-,NA|72aa|down_4|NZ_CP029190.1_4794784_4795000_-,NA|355aa|down_8|NZ_CP029190.1_4799183_4800248_+	NA|169aa|up_9|NZ_CP029190.1_4780713_4781220_-	pfam06210, DUF1003, Protein of unknown function (DUF1003)	NA|424aa|up_8|NZ_CP029190.1_4781419_4782691_-	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]	NA|261aa|up_7|NZ_CP029190.1_4782880_4783663_+	NA	NA|171aa|up_6|NZ_CP029190.1_4783659_4784172_-	NA	NA|373aa|up_5|NZ_CP029190.1_4784215_4785334_-	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily	NA|199aa|up_4|NZ_CP029190.1_4785603_4786200_+	pfam05076, SUFU, Suppressor of fused protein (SUFU)	NA|217aa|up_3|NZ_CP029190.1_4786284_4786935_+	NA	NA|291aa|up_2|NZ_CP029190.1_4787082_4787955_+	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]	NA|202aa|up_1|NZ_CP029190.1_4788019_4788625_+	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion]	NA|286aa|up_0|NZ_CP029190.1_4788939_4789797_-	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|253aa|down_0|NZ_CP029190.1_4792358_4793117_+	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	NA|98aa|down_1|NZ_CP029190.1_4793227_4793521_-	NA	NA|95aa|down_2|NZ_CP029190.1_4793656_4793941_-	pfam11305, DUF3107, Protein of unknown function (DUF3107)	NA|214aa|down_3|NZ_CP029190.1_4794018_4794660_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|72aa|down_4|NZ_CP029190.1_4794784_4795000_-	NA	NA|325aa|down_5|NZ_CP029190.1_4795134_4796109_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|468aa|down_6|NZ_CP029190.1_4796115_4797519_+	pfam11350, DUF3152, Protein of unknown function (DUF3152)	NA|497aa|down_7|NZ_CP029190.1_4797696_4799187_+	cd03813, GT4-like, glycosyltransferase family 4 proteins	NA|355aa|down_8|NZ_CP029190.1_4799183_4800248_+	NA	NA|331aa|down_9|NZ_CP029190.1_4800244_4801237_+	pfam01370, Epimerase, NAD dependent epimerase/dehydratase family
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	12	5141079-5141183	9	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	ATCCCCTGTAGCTCAATTGGCAGAGCA	27	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|100aa|up_0|NZ_CP029190.1_5140633_5140933_-,NA|223aa|down_0|NZ_CP029190.1_5141670_5142339_+,NA|244aa|down_7|NZ_CP029190.1_5149223_5149955_-	NA|246aa|up_9|NZ_CP029190.1_5128612_5129350_-	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]	NA|246aa|up_8|NZ_CP029190.1_5129693_5130431_+	COG2949, SanA, Uncharacterized membrane protein [Function unknown]	NA|261aa|up_7|NZ_CP029190.1_5130494_5131277_+	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs	NA|700aa|up_6|NZ_CP029190.1_5131344_5133444_+	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite	NA|365aa|up_5|NZ_CP029190.1_5133628_5134723_+	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|174aa|up_4|NZ_CP029190.1_5134753_5135275_+	PRK09752, PRK09752, AIDA-I family autotransporter YfaL	NA|642aa|up_3|NZ_CP029190.1_5135348_5137274_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|578aa|up_2|NZ_CP029190.1_5137270_5139004_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|486aa|up_1|NZ_CP029190.1_5139136_5140594_-	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|100aa|up_0|NZ_CP029190.1_5140633_5140933_-	NA	NA|223aa|down_0|NZ_CP029190.1_5141670_5142339_+	NA	NA|390aa|down_1|NZ_CP029190.1_5142395_5143565_-	PRK13517, PRK13517, glutamate--cysteine ligase	NA|434aa|down_2|NZ_CP029190.1_5144081_5145383_+	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|124aa|down_3|NZ_CP029190.1_5145466_5145838_-	cd02226, cupin_YdbB-like, Bacillus subtilis YdbB and related proteins, cupin domain	NA|264aa|down_4|NZ_CP029190.1_5145886_5146678_+	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|379aa|down_5|NZ_CP029190.1_5146693_5147830_+	pfam13449, Phytase-like, Esterase-like activity of phytase	NA|451aa|down_6|NZ_CP029190.1_5147855_5149208_-	COG0825, AccA, Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]	NA|244aa|down_7|NZ_CP029190.1_5149223_5149955_-	NA	NA|147aa|down_8|NZ_CP029190.1_5150025_5150466_+	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|542aa|down_9|NZ_CP029190.1_5150468_5152094_-	smart00065, GAF, Domain present in phytochromes and cGMP-specific phosphodiesterases
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	13	5489390-5489492	10	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GCGCGAGGAGCCCGCGGCCCCGGTC	25	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA,NA	NA|208aa|up_9|NZ_CP029190.1_5474190_5474814_-	cd03379, beta_CA_cladeD, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site	NA|320aa|up_8|NZ_CP029190.1_5475100_5476060_+	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA|659aa|up_7|NZ_CP029190.1_5476862_5478839_+	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|581aa|up_6|NZ_CP029190.1_5478876_5480619_+	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional	NA|475aa|up_5|NZ_CP029190.1_5480619_5482044_+	TIGR01143, murF, UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	NA|357aa|up_4|NZ_CP029190.1_5482040_5483111_+	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional	NA|534aa|up_3|NZ_CP029190.1_5483092_5484694_+	PRK01438, murD, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional	NA|454aa|up_2|NZ_CP029190.1_5484740_5486102_+	TIGR02614, Putative_lipid_II_flippase_FtsW, cell division protein FtsW	NA|365aa|up_1|NZ_CP029190.1_5486108_5487203_+	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional	NA|298aa|up_0|NZ_CP029190.1_5487218_5488112_+	PRK05529, PRK05529, cell division protein FtsQ; Provisional	NA|247aa|down_0|NZ_CP029190.1_5489611_5490352_+	pfam02578, Cu-oxidase_4, Multi-copper polyphenol oxidoreductase laccase	NA|240aa|down_1|NZ_CP029190.1_5490348_5491068_+	cd00635, PLPDE_III_YBL036c_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins	NA|206aa|down_2|NZ_CP029190.1_5491217_5491835_+	pfam04472, SepF, Cell division protein SepF	NA|99aa|down_3|NZ_CP029190.1_5491874_5492171_+	pfam02325, YGGT, YGGT family	NA|397aa|down_4|NZ_CP029190.1_5492250_5493441_+	pfam05103, DivIVA, DivIVA protein	NA|1049aa|down_5|NZ_CP029190.1_5493777_5496924_-	PRK06039, ileS, isoleucyl-tRNA synthetase; Reviewed	NA|254aa|down_6|NZ_CP029190.1_5497479_5498241_+	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family	NA|187aa|down_7|NZ_CP029190.1_5498355_5498916_+	PRK14764, PRK14764, lipoprotein signal peptidase; Provisional	NA|314aa|down_8|NZ_CP029190.1_5498933_5499875_+	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]	NA|155aa|down_9|NZ_CP029190.1_5499871_5500336_+	COG2153, ElaA, Predicted acyltransferase [General function prediction only]
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	14	5550876-5551031	11	CRISPRCasFinder	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	TCCCGGTCCCGGGGGCCGCGTACGGCGTCGCAGGCCCGCCGGGGGCGGGGC	51	0	0	NA	NA	NA	1	1	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA,NA	NA|418aa|up_9|NZ_CP029190.1_5539065_5540319_+	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated	NA|272aa|up_8|NZ_CP029190.1_5540315_5541131_+	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional	NA|290aa|up_7|NZ_CP029190.1_5541227_5542097_+	pfam13462, Thioredoxin_4, Thioredoxin	NA|339aa|up_6|NZ_CP029190.1_5542186_5543203_+	PRK13108, PRK13108, prolipoprotein diacylglyceryl transferase; Reviewed	NA|272aa|up_5|NZ_CP029190.1_5543255_5544071_-	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism]	NA|407aa|up_4|NZ_CP029190.1_5544067_5545288_-	pfam02515, CoA_transf_3, CoA-transferase family III	NA|303aa|up_3|NZ_CP029190.1_5545284_5546193_-	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP	NA|514aa|up_2|NZ_CP029190.1_5546189_5547731_-	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase	NA|401aa|up_1|NZ_CP029190.1_5547763_5548966_-	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase	NA|405aa|up_0|NZ_CP029190.1_5548962_5550177_-	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase	NA|329aa|down_0|NZ_CP029190.1_5551100_5552087_-	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase	NA|244aa|down_1|NZ_CP029190.1_5552346_5553078_+	cd02433, Nodulin-21_like_2, Nodulin-21 and CCC1-related protein family	NA|1532aa|down_2|NZ_CP029190.1_5553387_5557983_+	PRK11750, gltB, glutamate synthase subunit alpha; Provisional	NA|487aa|down_3|NZ_CP029190.1_5557975_5559436_+	PRK12810, gltD, glutamate synthase subunit beta; Reviewed	NA|686aa|down_4|NZ_CP029190.1_5559815_5561873_-	PRK13351, PRK13351, elongation factor G-like protein	NA|476aa|down_5|NZ_CP029190.1_5562320_5563748_+	pfam08924, DUF1906, Domain of unknown function (DUF1906)	NA|167aa|down_6|NZ_CP029190.1_5563751_5564252_-	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme	NA|192aa|down_7|NZ_CP029190.1_5564311_5564887_-	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|243aa|down_8|NZ_CP029190.1_5564998_5565727_+	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs	NA|343aa|down_9|NZ_CP029190.1_5565769_5566798_-	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	15	5815368-5815543	3	PILER-CR	no		cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Orphan	GCGGCGACCACCGAGGCCGTGACGACCGTGGCGGCGACCGT	41	0	0	NA	NA	NA	2	2	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA|261aa|up_9|NZ_CP029190.1_5798998_5799781_-,NA|87aa|down_7|NZ_CP029190.1_5823804_5824065_+	NA|261aa|up_9|NZ_CP029190.1_5798998_5799781_-	NA	NA|265aa|up_8|NZ_CP029190.1_5799878_5800673_+	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]	NA|143aa|up_7|NZ_CP029190.1_5800718_5801147_+	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]	NA|317aa|up_6|NZ_CP029190.1_5801184_5802135_+	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]	NA|276aa|up_5|NZ_CP029190.1_5802213_5803041_+	pfam01925, TauE, Sulfite exporter TauE/SafE	NA|168aa|up_4|NZ_CP029190.1_5803064_5803568_-	COG1403, McrA, Restriction endonuclease [Defense mechanisms]	NA|179aa|up_3|NZ_CP029190.1_5803716_5804253_-	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea	NA|1186aa|up_2|NZ_CP029190.1_5804330_5807888_+	cd15482, Sialidase_non-viral, Non-viral sialidases	NA|261aa|up_1|NZ_CP029190.1_5807955_5808738_-	pfam07070, Spo0M, SpoOM protein	NA|214aa|up_0|NZ_CP029190.1_5808849_5809491_+	pfam02245, Pur_DNA_glyco, Methylpurine-DNA glycosylase (MPG)	NA|282aa|down_0|NZ_CP029190.1_5816605_5817451_+	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|428aa|down_1|NZ_CP029190.1_5817516_5818800_-	pfam06245, DUF1015, Protein of unknown function (DUF1015)	NA|346aa|down_2|NZ_CP029190.1_5818898_5819936_+	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase	NA|310aa|down_3|NZ_CP029190.1_5820162_5821092_+	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease	NA|347aa|down_4|NZ_CP029190.1_5821094_5822135_+	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]	NA|270aa|down_5|NZ_CP029190.1_5822203_5823013_+	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]	NA|116aa|down_6|NZ_CP029190.1_5823411_5823759_-	pfam02036, SCP2, SCP-2 sterol transfer family	NA|87aa|down_7|NZ_CP029190.1_5823804_5824065_+	NA	NA|272aa|down_8|NZ_CP029190.1_5824072_5824888_+	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]	NA|314aa|down_9|NZ_CP029190.1_5824884_5825826_+	PRK03372, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional
GCF_008642295.1_ASM864229v1	NZ_CP029190	Streptomyces venezuelae strain ATCC 21782 chromosome, complete genome	16	5877783-5878122	12,2	CRISPRCasFinder,CRT	no	WYL	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	Unclear	CCCGGACCCCTCGGGCGCCAGGGCTCCGCCCGGCACCC,CNNNGCCCGTTCCCGGCCCG	38,20	0	0	NA	NA	NA:NA	1,4	4	Orphan	cas3HD,csa3,WYL,DEDDh,DinG,cas3,c2c9_V-U4,Cas9_archaeal,cas4,cas2,RT	NA,NA	NA|327aa|up_9|NZ_CP029190.1_5863619_5864600_-	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|372aa|up_8|NZ_CP029190.1_5864813_5865929_-	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase	NA|575aa|up_7|NZ_CP029190.1_5866206_5867931_+	PRK14995, PRK14995, SmvA family efflux MFS transporter	NA|389aa|up_6|NZ_CP029190.1_5868511_5869678_+	cd01151, GCD, Glutaryl-CoA dehydrogenase	NA|149aa|up_5|NZ_CP029190.1_5869704_5870151_-	pfam04472, SepF, Cell division protein SepF	NA|426aa|up_4|NZ_CP029190.1_5870439_5871717_+	pfam15240, Pro-rich, Proline-rich	NA|298aa|up_3|NZ_CP029190.1_5872757_5873651_+	pfam00089, Trypsin, Trypsin	NA|208aa|up_2|NZ_CP029190.1_5873758_5874382_-	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal	NA|462aa|up_1|NZ_CP029190.1_5874515_5875901_+	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]	NA|552aa|up_0|NZ_CP029190.1_5875947_5877603_+	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases	NA|1174aa|down_0|NZ_CP029190.1_5878451_5881973_+	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]	NA|326aa|down_1|NZ_CP029190.1_5882440_5883418_+	cd03586, PolY_Pol_IV_kappa, DNA Polymerase IV/Kappa	NA|400aa|down_2|NZ_CP029190.1_5883510_5884710_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|down_3|NZ_CP029190.1_5885243_5886008_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|287aa|down_4|NZ_CP029190.1_5886256_5887117_+	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]	NA|357aa|down_5|NZ_CP029190.1_5887143_5888214_-	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading	NA|165aa|down_6|NZ_CP029190.1_5888432_5888927_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|164aa|down_7|NZ_CP029190.1_5888931_5889423_-	pfam04167, DUF402, Protein of unknown function (DUF402)	NA|316aa|down_8|NZ_CP029190.1_5889419_5890367_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|149aa|down_9|NZ_CP029190.1_5890379_5890826_+	COG1725, COG1725, Predicted transcriptional regulators [Transcription]
