assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	1	1401781-1401864	1	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CGCGCGGGCGGGGGTGAGCCGGC	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|229aa|up_6|NZ_CP041650.2_1393321_1394008_-,NA|701aa|up_1|NZ_CP041650.2_1398239_1400342_+,NA|425aa|up_0|NZ_CP041650.2_1400331_1401606_+,NA|80aa|down_1|NZ_CP041650.2_1402894_1403134_+,NA|69aa|down_3|NZ_CP041650.2_1403879_1404086_+,NA|181aa|down_6|NZ_CP041650.2_1405812_1406355_+	NA|149aa|up_9|NZ_CP041650.2_1389133_1389580_-	pfam14085, DUF4265, Domain of unknown function (DUF4265)	NA|188aa|up_8|NZ_CP041650.2_1389846_1390410_+	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism]	NA|410aa|up_7|NZ_CP041650.2_1390850_1392080_-	PRK05868, PRK05868, FAD-binding protein	NA|229aa|up_6|NZ_CP041650.2_1393321_1394008_-	NA	NA|369aa|up_5|NZ_CP041650.2_1394220_1395327_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|226aa|up_4|NZ_CP041650.2_1395323_1396001_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|138aa|up_3|NZ_CP041650.2_1396130_1396544_+	smart01096, CPSase_L_D3, Carbamoyl-phosphate synthetase large chain, oligomerisation domain	NA|280aa|up_2|NZ_CP041650.2_1396809_1397649_-	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|701aa|up_1|NZ_CP041650.2_1398239_1400342_+	NA	NA|425aa|up_0|NZ_CP041650.2_1400331_1401606_+	NA	NA|196aa|down_0|NZ_CP041650.2_1402061_1402649_-	cd06133, ERI-1_3'hExo_like, DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins	NA|80aa|down_1|NZ_CP041650.2_1402894_1403134_+	NA	NA|78aa|down_2|NZ_CP041650.2_1403449_1403683_-	pfam03777, DUF320, Small secreted domain (DUF320)	NA|69aa|down_3|NZ_CP041650.2_1403879_1404086_+	NA	NA|217aa|down_4|NZ_CP041650.2_1404195_1404846_-	pfam14273, DUF4360, Domain of unknown function (DUF4360)	NA|191aa|down_5|NZ_CP041650.2_1405099_1405672_-	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea	NA|181aa|down_6|NZ_CP041650.2_1405812_1406355_+	NA	NA|389aa|down_7|NZ_CP041650.2_1406460_1407627_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|256aa|down_8|NZ_CP041650.2_1407626_1408394_+	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|253aa|down_9|NZ_CP041650.2_1408484_1409243_+	COG2186, FadR, Transcriptional regulators [Transcription]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	2	1561233-1561523	1,2,1	CRT,CRISPRCasFinder,PILER-CR	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CGTCCTCNCCCGCGCAGGC,GTCCTCCCCGCGCAGGCGGGGGTGAGCCG,CGTCCTCCCCGCGCAGGCGGGGGTGAGCCG	19,29,30	1	1	1561435-1561505	NZ_CP041650.2_1792894-1792824	NA:NA:NA	4,3,2	4	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|68aa|up_6|NZ_CP041650.2_1555525_1555729_+,NA|87aa|up_1|NZ_CP041650.2_1560407_1560668_-,NA|102aa|up_0|NZ_CP041650.2_1560664_1560970_-,NA|87aa|down_0|NZ_CP041650.2_1561536_1561797_+,NA|513aa|down_2|NZ_CP041650.2_1563320_1564859_-,NA|176aa|down_3|NZ_CP041650.2_1564932_1565460_-,NA|221aa|down_5|NZ_CP041650.2_1568262_1568925_+	NA|280aa|up_9|NZ_CP041650.2_1552872_1553712_+	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain	NA|198aa|up_8|NZ_CP041650.2_1553959_1554553_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|246aa|up_7|NZ_CP041650.2_1554658_1555396_+	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only]	NA|68aa|up_6|NZ_CP041650.2_1555525_1555729_+	NA	NA|302aa|up_5|NZ_CP041650.2_1555957_1556863_+	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases	NA|354aa|up_4|NZ_CP041650.2_1556940_1558002_+	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain	NA|160aa|up_3|NZ_CP041650.2_1558013_1558493_+	COG1846, MarR, Transcriptional regulators [Transcription]	NA|341aa|up_2|NZ_CP041650.2_1558790_1559813_-	pfam00535, Glycos_transf_2, Glycosyl transferase family 2	NA|87aa|up_1|NZ_CP041650.2_1560407_1560668_-	NA	NA|102aa|up_0|NZ_CP041650.2_1560664_1560970_-	NA	NA|87aa|down_0|NZ_CP041650.2_1561536_1561797_+	NA	NA|167aa|down_1|NZ_CP041650.2_1561960_1562461_+	pfam12587, DUF3761, Protein of unknown function (DUF3761)	NA|513aa|down_2|NZ_CP041650.2_1563320_1564859_-	NA	NA|176aa|down_3|NZ_CP041650.2_1564932_1565460_-	NA	NA|372aa|down_4|NZ_CP041650.2_1566029_1567145_+	pfam13565, HTH_32, Homeodomain-like domain	NA|221aa|down_5|NZ_CP041650.2_1568262_1568925_+	NA	NA|473aa|down_6|NZ_CP041650.2_1569456_1570875_+	NF033113, halo_ClmS, chloramphenicol-biosynthetic FADH2-dependent halogenase CmlS	NA|414aa|down_7|NZ_CP041650.2_1571163_1572405_+	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional	NA|224aa|down_8|NZ_CP041650.2_1572870_1573542_+	TIGR04539, CycloL-leucyl-L-phenylalanyl_synthase, tRNA-dependent cyclodipeptide synthase	NA|395aa|down_9|NZ_CP041650.2_1573531_1574716_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	3	1792883-1793338	2	CRT	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CGGCTCACCCCCGCCNNNGCGGGGNNGA	28	0	0	NA	NA	NA	7	7	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|94aa|up_9|NZ_CP041650.2_1786032_1786314_+,NA|128aa|up_7|NZ_CP041650.2_1787002_1787386_-,NA|138aa|up_5|NZ_CP041650.2_1788864_1789278_-,NA|82aa|up_4|NZ_CP041650.2_1789825_1790071_-,NA|74aa|up_3|NZ_CP041650.2_1790070_1790292_-,NA|87aa|up_0|NZ_CP041650.2_1792531_1792792_-,NA|77aa|down_2|NZ_CP041650.2_1798777_1799008_+,NA|82aa|down_6|NZ_CP041650.2_1801759_1802005_-,NA|188aa|down_9|NZ_CP041650.2_1808085_1808649_-	NA|94aa|up_9|NZ_CP041650.2_1786032_1786314_+	NA	NA|139aa|up_8|NZ_CP041650.2_1786452_1786869_-	pfam03995, Inhibitor_I36, Peptidase inhibitor family I36	NA|128aa|up_7|NZ_CP041650.2_1787002_1787386_-	NA	NA|330aa|up_6|NZ_CP041650.2_1787806_1788796_-	pfam00665, rve, Integrase core domain	NA|138aa|up_5|NZ_CP041650.2_1788864_1789278_-	NA	NA|82aa|up_4|NZ_CP041650.2_1789825_1790071_-	NA	NA|74aa|up_3|NZ_CP041650.2_1790070_1790292_-	NA	NA|333aa|up_2|NZ_CP041650.2_1790624_1791623_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|167aa|up_1|NZ_CP041650.2_1791867_1792368_-	pfam12587, DUF3761, Protein of unknown function (DUF3761)	NA|87aa|up_0|NZ_CP041650.2_1792531_1792792_-	NA	NA|452aa|down_0|NZ_CP041650.2_1794699_1796055_-	pfam00144, Beta-lactamase, Beta-lactamase	NA|228aa|down_1|NZ_CP041650.2_1796205_1796889_+	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain	NA|77aa|down_2|NZ_CP041650.2_1798777_1799008_+	NA	NA|72aa|down_3|NZ_CP041650.2_1799004_1799220_+	PRK00215, PRK00215, transcriptional repressor LexA	NA|316aa|down_4|NZ_CP041650.2_1799256_1800204_-	cd07906, Adenylation_DNA_ligase_LigD_LigC, Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases	NA|333aa|down_5|NZ_CP041650.2_1800447_1801446_+	pfam07485, DUF1529, Domain of Unknown Function (DUF1259)	NA|82aa|down_6|NZ_CP041650.2_1801759_1802005_-	NA	NA|439aa|down_7|NZ_CP041650.2_1804465_1805782_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|326aa|down_8|NZ_CP041650.2_1805870_1806848_+	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors	NA|188aa|down_9|NZ_CP041650.2_1808085_1808649_-	NA
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	4	2158675-2158794	3	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CGGATGATTGCCGGACCGGCCGCACGTGGC	30	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|501aa|up_6|NZ_CP041650.2_2146152_2147655_-,NA|122aa|up_3|NZ_CP041650.2_2151411_2151777_-,NA|166aa|up_0|NZ_CP041650.2_2158079_2158577_-,NA	NA|338aa|up_9|NZ_CP041650.2_2141141_2142155_+	TIGR04380, hypothetical_protein_HOLDEFILI_04020, inositol 2-dehydrogenase	NA|674aa|up_8|NZ_CP041650.2_2142173_2144195_-	TIGR03396, PC_PLC, phospholipase C, phosphocholine-specific, Pseudomonas-type	NA|477aa|up_7|NZ_CP041650.2_2144641_2146072_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|501aa|up_6|NZ_CP041650.2_2146152_2147655_-	NA	NA|381aa|up_5|NZ_CP041650.2_2147888_2149031_+	pfam01636, APH, Phosphotransferase enzyme family	NA|664aa|up_4|NZ_CP041650.2_2149359_2151351_+	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase	NA|122aa|up_3|NZ_CP041650.2_2151411_2151777_-	NA	NA|335aa|up_2|NZ_CP041650.2_2151835_2152840_-	COG1378, COG1378, Predicted transcriptional regulators [Transcription]	NA|340aa|up_1|NZ_CP041650.2_2157043_2158063_+	TIGR04027, Luciferase-like_monooxygenase, putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family	NA|166aa|up_0|NZ_CP041650.2_2158079_2158577_-	NA	NA|205aa|down_0|NZ_CP041650.2_2161837_2162452_-	pfam11706, zf-CGNR, CGNR zinc finger	NA|81aa|down_1|NZ_CP041650.2_2162707_2162950_-	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|389aa|down_2|NZ_CP041650.2_2163033_2164200_-	PRK08313, PRK08313, thiolase domain-containing protein	NA|352aa|down_3|NZ_CP041650.2_2164196_2165252_-	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|314aa|down_4|NZ_CP041650.2_2165252_2166194_-	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|267aa|down_5|NZ_CP041650.2_2166443_2167244_-	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|540aa|down_6|NZ_CP041650.2_2167431_2169051_+	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|515aa|down_7|NZ_CP041650.2_2169299_2170844_-	PRK08316, PRK08316, acyl-CoA synthetase; Validated	NA|808aa|down_8|NZ_CP041650.2_2171029_2173453_+	pfam01804, Penicil_amidase, Penicillin amidase	NA|517aa|down_9|NZ_CP041650.2_2173516_2175067_-	PRK08276, PRK08276, long-chain-fatty-acid--CoA ligase; Validated
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	5	3536256-3536391	4	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	GGTGGGGGCTTGGCGCGCAGTTCCCCGCGCCCCTGGGGGCGGGGCT	46	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|263aa|up_0|NZ_CP041650.2_3535448_3536237_+,NA	NA|431aa|up_9|NZ_CP041650.2_3520277_3521570_+	pfam06245, DUF1015, Protein of unknown function (DUF1015)	NA|264aa|up_8|NZ_CP041650.2_3521675_3522467_-	pfam04147, Nop14, Nop14-like family	NA|214aa|up_7|NZ_CP041650.2_3529978_3530620_-	pfam02245, Pur_DNA_glyco, Methylpurine-DNA glycosylase (MPG)	NA|262aa|up_6|NZ_CP041650.2_3530856_3531642_+	pfam07070, Spo0M, SpoOM protein	NA|178aa|up_5|NZ_CP041650.2_3531681_3532215_+	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional	NA|169aa|up_4|NZ_CP041650.2_3532373_3532880_+	COG1403, McrA, Restriction endonuclease [Defense mechanisms]	NA|312aa|up_3|NZ_CP041650.2_3532960_3533896_-	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]	NA|145aa|up_2|NZ_CP041650.2_3534027_3534462_-	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]	NA|264aa|up_1|NZ_CP041650.2_3534535_3535327_-	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]	NA|263aa|up_0|NZ_CP041650.2_3535448_3536237_+	NA	NA|82aa|down_0|NZ_CP041650.2_3536481_3536727_-	pfam03777, DUF320, Small secreted domain (DUF320)	NA|214aa|down_1|NZ_CP041650.2_3536886_3537528_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|390aa|down_2|NZ_CP041650.2_3537520_3538690_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|232aa|down_3|NZ_CP041650.2_3538878_3539574_+	cd05367, SPR-like_SDR_c, sepiapterin reductase (SPR)-like, classical (c) SDRs	NA|369aa|down_4|NZ_CP041650.2_3539570_3540677_+	pfam02547, Queuosine_synth, Queuosine biosynthesis protein	NA|258aa|down_5|NZ_CP041650.2_3540976_3541750_+	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains	NA|835aa|down_6|NZ_CP041650.2_3541834_3544339_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|587aa|down_7|NZ_CP041650.2_3544581_3546342_+	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau	NA|404aa|down_8|NZ_CP041650.2_3546453_3547665_+	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p	NA|173aa|down_9|NZ_CP041650.2_3547759_3548278_-	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	6	3841919-3842035	5	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CCTCCGGCCCCTTCCTCACACCCGACGGACTGAAAG	36	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA,NA|299aa|down_6|NZ_CP041650.2_3850638_3851535_+	NA|328aa|up_9|NZ_CP041650.2_3830405_3831389_+	COG0411, LivG, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]	NA|239aa|up_8|NZ_CP041650.2_3831385_3832102_+	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]	NA|128aa|up_7|NZ_CP041650.2_3832210_3832594_-	pfam10025, DUF2267, Uncharacterized conserved protein (DUF2267)	NA|217aa|up_6|NZ_CP041650.2_3832716_3833367_-	COG3707, AmiR, Response regulator with putative antiterminator output domain [Signal transduction mechanisms]	NA|259aa|up_5|NZ_CP041650.2_3833647_3834424_+	pfam13384, HTH_23, Homeodomain-like domain	NA|479aa|up_4|NZ_CP041650.2_3834433_3835870_-	PRK06247, PRK06247, pyruvate kinase; Provisional	NA|238aa|up_3|NZ_CP041650.2_3836020_3836734_-	pfam04402, SIMPL, Protein of unknown function (DUF541)	NA|605aa|up_2|NZ_CP041650.2_3836872_3838687_+	PRK09420, cpdB, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA|474aa|up_1|NZ_CP041650.2_3838810_3840232_-	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|455aa|up_0|NZ_CP041650.2_3840228_3841593_-	cd06450, DOPA_deC_like, DOPA decarboxylase family	NA|833aa|down_0|NZ_CP041650.2_3842558_3845057_-	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type	NA|197aa|down_1|NZ_CP041650.2_3845139_3845730_-	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs)	NA|123aa|down_2|NZ_CP041650.2_3845934_3846303_-	PRK09239, PRK09239, chorismate mutase; Provisional	NA|295aa|down_3|NZ_CP041650.2_3846314_3847199_-	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|590aa|down_4|NZ_CP041650.2_3847308_3849078_+	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35	NA|287aa|down_5|NZ_CP041650.2_3849625_3850486_-	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms	NA|299aa|down_6|NZ_CP041650.2_3850638_3851535_+	NA	NA|348aa|down_7|NZ_CP041650.2_3851631_3852675_+	sd00045, ANK, ankyrin repeats	NA|306aa|down_8|NZ_CP041650.2_3852754_3853672_-	PRK07791, PRK07791, short chain dehydrogenase; Provisional	NA|257aa|down_9|NZ_CP041650.2_3853668_3854439_-	PRK07856, PRK07856, SDR family oxidoreductase
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	7	4066532-4066650	6	CRISPRCasFinder	no	WYL	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Unclear	CCAGCCCCCACCGGCCCGCAGCCAAACGA	29	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|216aa|up_9|NZ_CP041650.2_4055757_4056405_-,NA|102aa|up_4|NZ_CP041650.2_4061972_4062278_-,NA|480aa|down_1|NZ_CP041650.2_4068240_4069680_-,NA|66aa|down_4|NZ_CP041650.2_4072580_4072778_+,NA|106aa|down_8|NZ_CP041650.2_4075843_4076161_-	NA|216aa|up_9|NZ_CP041650.2_4055757_4056405_-	NA	NA|208aa|up_8|NZ_CP041650.2_4056696_4057320_+	COG1802, GntR, Transcriptional regulators [Transcription]	NA|901aa|up_7|NZ_CP041650.2_4057584_4060287_+	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed	WYL|333aa|up_6|NZ_CP041650.2_4060398_4061397_+	COG2378, COG2378, Predicted transcriptional regulator [Transcription]	NA|173aa|up_5|NZ_CP041650.2_4061487_4062006_+	pfam14024, DUF4240, Protein of unknown function (DUF4240)	NA|102aa|up_4|NZ_CP041650.2_4061972_4062278_-	NA	NA|292aa|up_3|NZ_CP041650.2_4062653_4063529_-	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme	NA|395aa|up_2|NZ_CP041650.2_4063653_4064838_+	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|166aa|up_1|NZ_CP041650.2_4064839_4065337_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|309aa|up_0|NZ_CP041650.2_4065399_4066326_+	TIGR01777, Hypothetical_UPF0105_protein_Rv2216/MT2273/Mb2239	NA|451aa|down_0|NZ_CP041650.2_4066886_4068239_+	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase	NA|480aa|down_1|NZ_CP041650.2_4068240_4069680_-	NA	NA|266aa|down_2|NZ_CP041650.2_4069982_4070780_+	PRK14345, PRK14345, lipoyl(octanoyl) transferase LipB	NA|322aa|down_3|NZ_CP041650.2_4071299_4072265_+	PRK05481, PRK05481, lipoyl synthase; Provisional	NA|66aa|down_4|NZ_CP041650.2_4072580_4072778_+	NA	NA|234aa|down_5|NZ_CP041650.2_4072867_4073569_+	pfam13829, DUF4191, Domain of unknown function (DUF4191)	NA|157aa|down_6|NZ_CP041650.2_4073683_4074154_-	pfam06271, RDD, RDD family	NA|470aa|down_7|NZ_CP041650.2_4074353_4075763_+	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I	NA|106aa|down_8|NZ_CP041650.2_4075843_4076161_-	NA	NA|308aa|down_9|NZ_CP041650.2_4076521_4077445_+	PRK02391, PRK02391, heat shock protein HtpX; Provisional
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	8	4360755-4360843	7	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CGCCGAACAGGCTGAATGGTGCG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA,NA|288aa|down_0|NZ_CP041650.2_4361126_4361990_-,NA|323aa|down_8|NZ_CP041650.2_4370653_4371622_+	NA|327aa|up_9|NZ_CP041650.2_4350406_4351387_+	cd09019, galactose_mutarotase_like, galactose mutarotase_like	NA|279aa|up_8|NZ_CP041650.2_4351408_4352245_-	pfam09770, PAT1, Topoisomerase II-associated protein PAT1	NA|841aa|up_7|NZ_CP041650.2_4352371_4354894_-	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]	NA|192aa|up_6|NZ_CP041650.2_4355084_4355660_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|110aa|up_5|NZ_CP041650.2_4355698_4356028_-	pfam10823, DUF2568, Protein of unknown function (DUF2568)	NA|139aa|up_4|NZ_CP041650.2_4356053_4356470_-	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis]	NA|271aa|up_3|NZ_CP041650.2_4356481_4357294_-	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]	NA|314aa|up_2|NZ_CP041650.2_4357334_4358276_+	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|418aa|up_1|NZ_CP041650.2_4358406_4359660_+	cd00501, Peptidase_C15, Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins	NA|275aa|up_0|NZ_CP041650.2_4359702_4360527_-	COG2981, CysZ, Uncharacterized protein involved in cysteine biosynthesis [Amino acid transport and metabolism]	NA|288aa|down_0|NZ_CP041650.2_4361126_4361990_-	NA	NA|853aa|down_1|NZ_CP041650.2_4362285_4364844_+	cd06244, M14-like, Peptidase M14-like domain; uncharacterized subgroup	NA|140aa|down_2|NZ_CP041650.2_4364929_4365349_-	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily	NA|340aa|down_3|NZ_CP041650.2_4365484_4366504_-	cd05288, PGDH, Prostaglandin dehydrogenases	NA|145aa|down_4|NZ_CP041650.2_4366628_4367063_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|235aa|down_5|NZ_CP041650.2_4367203_4367908_-	pfam02724, CDC45, CDC45-like protein	NA|386aa|down_6|NZ_CP041650.2_4368278_4369436_+	cd03316, MR_like, Mandelate racemase (MR)-like subfamily of the enolase superfamily	NA|335aa|down_7|NZ_CP041650.2_4369432_4370437_+	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases	NA|323aa|down_8|NZ_CP041650.2_4370653_4371622_+	NA	NA|374aa|down_9|NZ_CP041650.2_4371754_4372876_+	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	9	4968519-4968640	8	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	AGGGGCGCGGGGAACTGCGCGACCAGCCCCCA	32	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|481aa|up_9|NZ_CP041650.2_4953816_4955259_+,NA|535aa|up_6|NZ_CP041650.2_4958288_4959893_+,NA|128aa|up_4|NZ_CP041650.2_4961385_4961769_+,NA|212aa|up_3|NZ_CP041650.2_4961960_4962596_+,NA	NA|481aa|up_9|NZ_CP041650.2_4953816_4955259_+	NA	NA|199aa|up_8|NZ_CP041650.2_4955279_4955876_-	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1)	NA|333aa|up_7|NZ_CP041650.2_4956134_4957133_+	pfam14378, PAP2_3, PAP2 superfamily	NA|535aa|up_6|NZ_CP041650.2_4958288_4959893_+	NA	NA|445aa|up_5|NZ_CP041650.2_4959889_4961224_+	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]	NA|128aa|up_4|NZ_CP041650.2_4961385_4961769_+	NA	NA|212aa|up_3|NZ_CP041650.2_4961960_4962596_+	NA	NA|487aa|up_2|NZ_CP041650.2_4962729_4964190_-	TIGR03296, hypothetical_protein, M6 family metalloprotease domain	NA|687aa|up_1|NZ_CP041650.2_4964748_4966809_+	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase	NA|365aa|up_0|NZ_CP041650.2_4966878_4967973_-	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1	NA|244aa|down_0|NZ_CP041650.2_4968659_4969391_-	COG3473, COG3473, Maleate cis-trans isomerase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|261aa|down_1|NZ_CP041650.2_4969387_4970170_-	COG3473, COG3473, Maleate cis-trans isomerase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|308aa|down_2|NZ_CP041650.2_4970496_4971420_+	cd05300, 2-Hacid_dh_1, Putative D-isomer specific 2-hydroxyacid dehydrogenase	NA|468aa|down_3|NZ_CP041650.2_4971440_4972844_+	PRK06169, PRK06169, putative amidase; Provisional	NA|165aa|down_4|NZ_CP041650.2_4972900_4973395_-	pfam12903, DUF3830, Protein of unknown function (DUF3830)	NA|310aa|down_5|NZ_CP041650.2_4973502_4974432_+	cd01002, PBP2_Ehub_like, Substrate binding domain of ectoine/hydroxyectoine specific ABC transport system; the type 2 periplasmic binding protein fold	NA|240aa|down_6|NZ_CP041650.2_4974428_4975148_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|217aa|down_7|NZ_CP041650.2_4975144_4975795_+	TIGR03003, ectoine_ehuD, ectoine/hydroxyectoine ABC transporter, permease protein EhuD	NA|273aa|down_8|NZ_CP041650.2_4975796_4976615_+	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|253aa|down_9|NZ_CP041650.2_4976831_4977590_+	COG1414, IclR, Transcriptional regulator [Transcription]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	10	5277577-5277698	9	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	AGGGGCGCGGGGAACTGCGCGACCAGCCCCCGCCCAC	37	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|500aa|up_6|NZ_CP041650.2_5266538_5268038_-,NA	NA|454aa|up_9|NZ_CP041650.2_5263127_5264489_-	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed	NA|142aa|up_8|NZ_CP041650.2_5265280_5265706_-	pfam12005, DUF3499, Protein of unknown function (DUF3499)	NA|150aa|up_7|NZ_CP041650.2_5266007_5266457_+	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria	NA|500aa|up_6|NZ_CP041650.2_5266538_5268038_-	NA	NA|1224aa|up_5|NZ_CP041650.2_5268034_5271706_-	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only]	NA|88aa|up_4|NZ_CP041650.2_5271892_5272156_-	pfam02467, Whib, Transcription factor WhiB	NA|164aa|up_3|NZ_CP041650.2_5272862_5273354_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|320aa|up_2|NZ_CP041650.2_5273416_5274376_+	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional	NA|424aa|up_1|NZ_CP041650.2_5274507_5275779_+	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional	NA|338aa|up_0|NZ_CP041650.2_5276051_5277065_+	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]	NA|361aa|down_0|NZ_CP041650.2_5277718_5278801_-	COG1208, GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis]	NA|445aa|down_1|NZ_CP041650.2_5278920_5280255_-	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme	NA|252aa|down_2|NZ_CP041650.2_5280384_5281140_+	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein	NA|417aa|down_3|NZ_CP041650.2_5281359_5282610_+	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|581aa|down_4|NZ_CP041650.2_5282854_5284597_+	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|620aa|down_5|NZ_CP041650.2_5284738_5286598_+	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|347aa|down_6|NZ_CP041650.2_5286686_5287727_-	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan	NA|519aa|down_7|NZ_CP041650.2_5287799_5289356_+	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|429aa|down_8|NZ_CP041650.2_5289429_5290716_-	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|182aa|down_9|NZ_CP041650.2_5290835_5291381_+	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	11	5661284-5661371	10	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CTACTTCACGAAGTCGTAGACGG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA,NA|151aa|down_2|NZ_CP041650.2_5663540_5663993_-,NA|448aa|down_3|NZ_CP041650.2_5665517_5666861_-	NA|268aa|up_9|NZ_CP041650.2_5649244_5650048_+	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily	NA|776aa|up_8|NZ_CP041650.2_5650204_5652532_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|251aa|up_7|NZ_CP041650.2_5652692_5653445_-	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains	NA|212aa|up_6|NZ_CP041650.2_5653612_5654248_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|165aa|up_5|NZ_CP041650.2_5654331_5654826_-	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c	NA|397aa|up_4|NZ_CP041650.2_5654825_5656016_-	cd00567, ACAD, Acyl-CoA dehydrogenase	NA|389aa|up_3|NZ_CP041650.2_5656130_5657297_+	PRK06158, PRK06158, thiolase; Provisional	NA|264aa|up_2|NZ_CP041650.2_5657572_5658364_-	pfam08241, Methyltransf_11, Methyltransferase domain	NA|224aa|up_1|NZ_CP041650.2_5658607_5659279_+	PRK05679, PRK05679, pyridoxal 5'-phosphate synthase	NA|325aa|up_0|NZ_CP041650.2_5659215_5660190_-	PRK09906, PRK09906, DNA-binding transcriptional regulator HcaR; Provisional	NA|208aa|down_0|NZ_CP041650.2_5662324_5662948_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|179aa|down_1|NZ_CP041650.2_5662978_5663515_-	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|151aa|down_2|NZ_CP041650.2_5663540_5663993_-	NA	NA|448aa|down_3|NZ_CP041650.2_5665517_5666861_-	NA	NA|742aa|down_4|NZ_CP041650.2_5667128_5669354_+	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion]	NA|298aa|down_5|NZ_CP041650.2_5669427_5670321_+	PRK06688, PRK06688, enoyl-CoA hydratase; Provisional	NA|202aa|down_6|NZ_CP041650.2_5670389_5670995_+	smart00903, Flavin_Reduct, Flavin reductase like domain	NA|475aa|down_7|NZ_CP041650.2_5671032_5672457_-	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters	NA|350aa|down_8|NZ_CP041650.2_5674575_5675625_-	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase	NA|382aa|down_9|NZ_CP041650.2_5675635_5676781_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	12	6983851-6983951	11	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	TCGCGCAGTTCCCCGCGCCCCTGAA	25	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|130aa|up_6|NZ_CP041650.2_6978491_6978881_-,NA	NA|153aa|up_9|NZ_CP041650.2_6975400_6975859_-	cd01285, nucleoside_deaminase, Nucleoside deaminases include adenosine, guanine and cytosine deaminases	NA|427aa|up_8|NZ_CP041650.2_6975960_6977241_+	pfam07905, PucR, Purine catabolism regulatory protein-like family	NA|359aa|up_7|NZ_CP041650.2_6977264_6978341_-	cd19608, GH113_mannanase-like, Glycoside hydrolase family 113 beta-1,4-mannanase and similar proteins	NA|130aa|up_6|NZ_CP041650.2_6978491_6978881_-	NA	NA|217aa|up_5|NZ_CP041650.2_6978930_6979581_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|338aa|up_4|NZ_CP041650.2_6979643_6980657_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|112aa|up_3|NZ_CP041650.2_6980774_6981110_+	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|205aa|up_2|NZ_CP041650.2_6981141_6981756_+	pfam12167, Arm-DNA-bind_2, Arm DNA-binding domain	NA|464aa|up_1|NZ_CP041650.2_6981760_6983152_-	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain	NA|136aa|up_0|NZ_CP041650.2_6983241_6983649_-	pfam13396, PLDc_N, Phospholipase_D-nuclease N-terminal	NA|486aa|down_0|NZ_CP041650.2_6984301_6985759_+	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family	NA|302aa|down_1|NZ_CP041650.2_6985805_6986711_+	PRK12888, ubiA, 4-hydroxybenzoate octaprenyltransferase	NA|225aa|down_2|NZ_CP041650.2_6986742_6987417_+	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism]	NA|152aa|down_3|NZ_CP041650.2_6987540_6987996_+	smart00344, HTH_ASNC, helix_turn_helix ASNC type	NA|388aa|down_4|NZ_CP041650.2_6988081_6989245_+	TIGR03700, mena_SCO4494, putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family	NA|180aa|down_5|NZ_CP041650.2_6989427_6989967_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|102aa|down_6|NZ_CP041650.2_6990061_6990367_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|215aa|down_7|NZ_CP041650.2_6990409_6991054_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|286aa|down_8|NZ_CP041650.2_6991059_6991917_-	cd03453, SAV4209_like, SAV4209_like	NA|452aa|down_9|NZ_CP041650.2_6992168_6993524_-	PRK08261, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	13	7838796-7838934	12	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	GGGGCGGAGCCCCGCCTGAGGGGCGCGGGGAACTGCGCGTCAGCCCCCACC	51	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA,NA|276aa|down_5|NZ_CP041650.2_7843284_7844112_+,NA|61aa|down_6|NZ_CP041650.2_7844141_7844324_-	NA|291aa|up_9|NZ_CP041650.2_7829364_7830237_-	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain	NA|318aa|up_8|NZ_CP041650.2_7830405_7831359_+	cd08267, MDR1, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|132aa|up_7|NZ_CP041650.2_7831599_7831995_-	TIGR02753, Superoxide_dismutase, superoxide dismutase, Ni	NA|145aa|up_6|NZ_CP041650.2_7832139_7832574_+	TIGR02754, putative_signal_peptidase, nickel-type superoxide dismutase maturation protease	NA|210aa|up_5|NZ_CP041650.2_7832477_7833107_-	pfam11706, zf-CGNR, CGNR zinc finger	NA|263aa|up_4|NZ_CP041650.2_7833217_7834006_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|265aa|up_3|NZ_CP041650.2_7834104_7834899_-	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|313aa|up_2|NZ_CP041650.2_7834895_7835834_-	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|319aa|up_1|NZ_CP041650.2_7835872_7836829_-	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold	NA|425aa|up_0|NZ_CP041650.2_7837372_7838647_+	COG0281, SfcA, Malic enzyme [Energy production and conversion]	NA|322aa|down_0|NZ_CP041650.2_7839118_7840084_+	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family	NA|70aa|down_1|NZ_CP041650.2_7840228_7840438_+	PRK00118, PRK00118, putative DNA-binding protein; Validated	NA|189aa|down_2|NZ_CP041650.2_7840437_7841004_+	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB	NA|355aa|down_3|NZ_CP041650.2_7841109_7842174_-	pfam03551, PadR, Transcriptional regulator PadR-like family	NA|292aa|down_4|NZ_CP041650.2_7842175_7843051_-	COG3595, COG3595, Uncharacterized conserved protein [Function unknown]	NA|276aa|down_5|NZ_CP041650.2_7843284_7844112_+	NA	NA|61aa|down_6|NZ_CP041650.2_7844141_7844324_-	NA	NA|1276aa|down_7|NZ_CP041650.2_7844501_7848329_-	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|368aa|down_8|NZ_CP041650.2_7848611_7849715_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|246aa|down_9|NZ_CP041650.2_7849801_7850539_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	14	7881517-7881730	2	PILER-CR	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CCGGTCCGTATCACTCAGCCTGTCCGGCGTGTGAGGCTGAGGTCGGGGGTCGAT	54	2	8	7881571-7881602|7881571-7881602|7881571-7881602|7881571-7881602|7881657-7881688|7881657-7881688|7881657-7881688|7881657-7881688	NZ_CP041650.2_8222034-8222065|NZ_CP041650.2_7881735-7881766|NZ_CP041650.2_5262630-5262599|NZ_CP041650.2_5277262-5277231|NZ_CP041650.2_8222034-8222065|NZ_CP041650.2_7881735-7881766|NZ_CP041650.2_5262630-5262599|NZ_CP041650.2_5277262-5277231	NA	2	2	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|174aa|up_4|NZ_CP041650.2_7876630_7877152_-,NA|277aa|up_2|NZ_CP041650.2_7878587_7879418_-,NA	NA|303aa|up_9|NZ_CP041650.2_7870793_7871702_+	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase	NA|242aa|up_8|NZ_CP041650.2_7871720_7872446_-	TIGR03943, TIGR03943, TIGR03943 family protein	NA|306aa|up_7|NZ_CP041650.2_7872442_7873360_-	COG0701, COG0701, Predicted permeases [General function prediction only]	NA|485aa|up_6|NZ_CP041650.2_7873704_7875159_-	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|465aa|up_5|NZ_CP041650.2_7875155_7876550_-	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning]	NA|174aa|up_4|NZ_CP041650.2_7876630_7877152_-	NA	NA|446aa|up_3|NZ_CP041650.2_7877253_7878591_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|277aa|up_2|NZ_CP041650.2_7878587_7879418_-	NA	NA|169aa|up_1|NZ_CP041650.2_7879688_7880195_-	smart00195, DSPc, Dual specificity phosphatase, catalytic domain	NA|268aa|up_0|NZ_CP041650.2_7880292_7881096_+	pfam08378, NERD, Nuclease-related domain	NA|289aa|down_0|NZ_CP041650.2_7881921_7882788_-	cd04863, MtLigD_Pol_like, MtLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Mycobacterium tuberculosis (Mt)LigD	NA|376aa|down_1|NZ_CP041650.2_7882961_7884089_+	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku	NA|587aa|down_2|NZ_CP041650.2_7884180_7885941_-	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II	NA|362aa|down_3|NZ_CP041650.2_7886202_7887288_-	TIGR03945, cysteine_synthase, 2,3-diaminopropionate biosynthesis protein SbnA	NA|365aa|down_4|NZ_CP041650.2_7887445_7888540_-	TIGR03944, ornithine_cyclodeaminase, 2,3-diaminopropionate biosynthesis protein SbnB	NA|335aa|down_5|NZ_CP041650.2_7888536_7889541_-	pfam02668, TauD, Taurine catabolism dioxygenase TauD, TfdA family	NA|1083aa|down_6|NZ_CP041650.2_7889662_7892911_-	cd05930, A_NRPS, The adenylation domain of nonribosomal peptide synthetases (NRPS)	NA|861aa|down_7|NZ_CP041650.2_7892907_7895490_-	TIGR02353, NON-RIBOSOMAL_PEPTIDE_SYNTHETASE, non-ribosomal peptide synthetase terminal domain of unknown function	NA|656aa|down_8|NZ_CP041650.2_7896328_7898296_-	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase	NA|444aa|down_9|NZ_CP041650.2_7898684_7900016_-	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	15	8189000-8189112	13	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	GGGGCATCGGCCTTCGGCCTTGTCCTCA	28	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|79aa|up_9|NZ_CP041650.2_8172967_8173204_+,NA|69aa|down_8|NZ_CP041650.2_8200427_8200634_-	NA|79aa|up_9|NZ_CP041650.2_8172967_8173204_+	NA	NA|403aa|up_8|NZ_CP041650.2_8173231_8174440_-	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase	NA|336aa|up_7|NZ_CP041650.2_8174503_8175511_-	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR)	NA|310aa|up_6|NZ_CP041650.2_8175599_8176529_+	cd12166, 2-Hacid_dh_7, Putative D-isomer specific 2-hydroxyacid dehydrogenases	NA|1078aa|up_5|NZ_CP041650.2_8176726_8179960_+	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase	NA|619aa|up_4|NZ_CP041650.2_8180186_8182043_+	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated	NA|177aa|up_3|NZ_CP041650.2_8182070_8182601_+	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed	NA|333aa|up_2|NZ_CP041650.2_8182716_8183715_+	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional	NA|530aa|up_1|NZ_CP041650.2_8184145_8185735_+	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional	NA|989aa|up_0|NZ_CP041650.2_8185817_8188784_-	COG3899, COG3899, Predicted ATPase [General function prediction only]	NA|522aa|down_0|NZ_CP041650.2_8189607_8191173_-	PRK14995, PRK14995, SmvA family efflux MFS transporter	NA|196aa|down_1|NZ_CP041650.2_8191270_8191858_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|399aa|down_2|NZ_CP041650.2_8191862_8193059_-	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily	NA|484aa|down_3|NZ_CP041650.2_8193106_8194558_+	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|415aa|down_4|NZ_CP041650.2_8194605_8195850_-	COG3214, COG3214, Uncharacterized protein conserved in bacteria [Function unknown]	NA|436aa|down_5|NZ_CP041650.2_8195947_8197255_-	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|309aa|down_6|NZ_CP041650.2_8197436_8198363_+	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism]	NA|547aa|down_7|NZ_CP041650.2_8198412_8200053_+	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17	NA|69aa|down_8|NZ_CP041650.2_8200427_8200634_-	NA	NA|645aa|down_9|NZ_CP041650.2_8200790_8202725_-	pfam10566, Glyco_hydro_97, Glycoside hydrolase 97
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	16	8388693-8388837	14	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	GTCTGTCGCTGGTCGCGCAGTTCCCCGCGCCCCTCGGGCCGGGGCTGCGCCCCG	54	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|159aa|up_5|NZ_CP041650.2_8379222_8379699_+,NA|164aa|down_8|NZ_CP041650.2_8403967_8404459_-	NA|387aa|up_9|NZ_CP041650.2_8374671_8375832_+	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]	NA|308aa|up_8|NZ_CP041650.2_8375831_8376755_+	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]	NA|267aa|up_7|NZ_CP041650.2_8376755_8377556_+	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]	NA|473aa|up_6|NZ_CP041650.2_8377628_8379047_+	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase	NA|159aa|up_5|NZ_CP041650.2_8379222_8379699_+	NA	NA|603aa|up_4|NZ_CP041650.2_8379837_8381646_+	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD)	NA|286aa|up_3|NZ_CP041650.2_8381633_8382491_-	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|445aa|up_2|NZ_CP041650.2_8382661_8383996_-	PRK06058, PRK06058, 4-aminobutyrate--2-oxoglutarate transaminase	NA|818aa|up_1|NZ_CP041650.2_8384328_8386782_+	PRK14965, PRK14965, DNA polymerase III subunits gamma and tau; Provisional	NA|554aa|up_0|NZ_CP041650.2_8386931_8388593_+	pfam07905, PucR, Purine catabolism regulatory protein-like family	NA|482aa|down_0|NZ_CP041650.2_8389165_8390611_+	cd07147, ALDH_F21_RNP123, Aldehyde dehydrogenase family 21A1-like	NA|952aa|down_1|NZ_CP041650.2_8390733_8393589_-	PLN03080, PLN03080, Probable beta-xylosidase; Provisional	NA|566aa|down_2|NZ_CP041650.2_8393964_8395662_+	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold	NA|345aa|down_3|NZ_CP041650.2_8395689_8396724_+	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]	NA|312aa|down_4|NZ_CP041650.2_8396720_8397656_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|660aa|down_5|NZ_CP041650.2_8398951_8400931_+	pfam02449, Glyco_hydro_42, Beta-galactosidase	NA|758aa|down_6|NZ_CP041650.2_8400927_8403201_+	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain	NA|238aa|down_7|NZ_CP041650.2_8403236_8403950_+	PRK06215, PRK06215, hypothetical protein; Provisional	NA|164aa|down_8|NZ_CP041650.2_8403967_8404459_-	NA	NA|684aa|down_9|NZ_CP041650.2_8404575_8406627_-	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	17	8419298-8419438	15	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	ACGCACCCGCAGACAAGCGATCCGGGGCCGTCGTCGTATCCGGGGCGCAG	50	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|162aa|up_5|NZ_CP041650.2_8411167_8411653_+,NA	NA|684aa|up_9|NZ_CP041650.2_8404575_8406627_-	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]	NA|338aa|up_8|NZ_CP041650.2_8406809_8407823_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|269aa|up_7|NZ_CP041650.2_8408161_8408968_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|644aa|up_6|NZ_CP041650.2_8409132_8411064_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|162aa|up_5|NZ_CP041650.2_8411167_8411653_+	NA	NA|923aa|up_4|NZ_CP041650.2_8411669_8414438_+	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed	NA|151aa|up_3|NZ_CP041650.2_8414468_8414921_-	pfam00932, LTD, Lamin Tail Domain	NA|428aa|up_2|NZ_CP041650.2_8415141_8416425_+	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional	NA|435aa|up_1|NZ_CP041650.2_8416421_8417726_+	cd06163, S2P-M50_PDZ_RseP-like, RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms	NA|386aa|up_0|NZ_CP041650.2_8417900_8419058_+	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA|283aa|down_0|NZ_CP041650.2_8419691_8420540_+	pfam13312, DUF4081, Domain of unknown function (DUF4081)	NA|190aa|down_1|NZ_CP041650.2_8420723_8421293_+	COG0456, RimI, Acetyltransferases [General function prediction only]	NA|566aa|down_2|NZ_CP041650.2_8421365_8423063_+	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional	NA|109aa|down_3|NZ_CP041650.2_8423215_8423542_+	COG1429, CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases [Coenzyme metabolism]	NA|326aa|down_4|NZ_CP041650.2_8423541_8424519_+	pfam02424, ApbE, ApbE family	NA|200aa|down_5|NZ_CP041650.2_8424515_8425115_+	pfam01794, Ferric_reduct, Ferric reductase like transmembrane component	NA|420aa|down_6|NZ_CP041650.2_8425111_8426371_+	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]	NA|82aa|down_7|NZ_CP041650.2_8426372_8426618_+	pfam13459, Fer4_15, 4Fe-4S single cluster domain	NA|314aa|down_8|NZ_CP041650.2_8426630_8427572_-	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase	NA|164aa|down_9|NZ_CP041650.2_8427662_8428154_-	pfam14530, DUF4439, Domain of unknown function (DUF4439)
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	18	9012715-9012799	16	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	GAGGACGGCGACAGCTGGTGACC	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|449aa|up_8|NZ_CP041650.2_8994724_8996071_+,NA|291aa|up_5|NZ_CP041650.2_8999098_8999971_+,NA|841aa|up_4|NZ_CP041650.2_8999976_9002499_+,NA|352aa|up_3|NZ_CP041650.2_9002533_9003589_+,NA|183aa|up_2|NZ_CP041650.2_9003585_9004134_+,NA|257aa|down_2|NZ_CP041650.2_9018506_9019277_+	NA|336aa|up_9|NZ_CP041650.2_8992635_8993643_+	cd12167, 2-Hacid_dh_8, Putative D-isomer specific 2-hydroxyacid dehydrogenases	NA|449aa|up_8|NZ_CP041650.2_8994724_8996071_+	NA	NA|504aa|up_7|NZ_CP041650.2_8996348_8997860_+	pfam00553, CBM_2, Cellulose binding domain	NA|238aa|up_6|NZ_CP041650.2_8998270_8998984_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|291aa|up_5|NZ_CP041650.2_8999098_8999971_+	NA	NA|841aa|up_4|NZ_CP041650.2_8999976_9002499_+	NA	NA|352aa|up_3|NZ_CP041650.2_9002533_9003589_+	NA	NA|183aa|up_2|NZ_CP041650.2_9003585_9004134_+	NA	NA|772aa|up_1|NZ_CP041650.2_9004191_9006507_+	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|1158aa|up_0|NZ_CP041650.2_9006643_9010117_+	pfam13809, Tubulin_2, Tubulin like	NA|709aa|down_0|NZ_CP041650.2_9014925_9017052_+	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau	NA|262aa|down_1|NZ_CP041650.2_9017665_9018451_+	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation	NA|257aa|down_2|NZ_CP041650.2_9018506_9019277_+	NA	NA|474aa|down_3|NZ_CP041650.2_9019244_9020666_-	COG0635, HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]	NA|338aa|down_4|NZ_CP041650.2_9020736_9021750_-	pfam10343, Q_salvage, Potential Queuosine, Q, salvage protein family	NA|1015aa|down_5|NZ_CP041650.2_9021779_9024824_-	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1	NA|906aa|down_6|NZ_CP041650.2_9026091_9028809_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|370aa|down_7|NZ_CP041650.2_9029055_9030165_+	PRK01889, PRK01889, GTPase RsgA; Reviewed	NA|467aa|down_8|NZ_CP041650.2_9030640_9032041_+	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism]	NA|123aa|down_9|NZ_CP041650.2_9032712_9033081_-	TIGR04023, Pyridoxamine_5'-phosphate_oxidase, PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	19	9030252-9030384	17	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	GCGCAGTTCCCCGCGCCCCTGAGGCGGGGGCTTCGCCCCGC	41	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|874aa|up_8|NZ_CP041650.2_9010113_9012735_+,NA|257aa|up_5|NZ_CP041650.2_9018506_9019277_+,NA|771aa|down_3|NZ_CP041650.2_9034515_9036828_-	NA|1158aa|up_9|NZ_CP041650.2_9006643_9010117_+	pfam13809, Tubulin_2, Tubulin like	NA|874aa|up_8|NZ_CP041650.2_9010113_9012735_+	NA	NA|709aa|up_7|NZ_CP041650.2_9014925_9017052_+	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau	NA|262aa|up_6|NZ_CP041650.2_9017665_9018451_+	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation	NA|257aa|up_5|NZ_CP041650.2_9018506_9019277_+	NA	NA|474aa|up_4|NZ_CP041650.2_9019244_9020666_-	COG0635, HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]	NA|338aa|up_3|NZ_CP041650.2_9020736_9021750_-	pfam10343, Q_salvage, Potential Queuosine, Q, salvage protein family	NA|1015aa|up_2|NZ_CP041650.2_9021779_9024824_-	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1	NA|906aa|up_1|NZ_CP041650.2_9026091_9028809_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|370aa|up_0|NZ_CP041650.2_9029055_9030165_+	PRK01889, PRK01889, GTPase RsgA; Reviewed	NA|467aa|down_0|NZ_CP041650.2_9030640_9032041_+	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism]	NA|123aa|down_1|NZ_CP041650.2_9032712_9033081_-	TIGR04023, Pyridoxamine_5'-phosphate_oxidase, PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family	NA|414aa|down_2|NZ_CP041650.2_9033277_9034519_+	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE	NA|771aa|down_3|NZ_CP041650.2_9034515_9036828_-	NA	NA|161aa|down_4|NZ_CP041650.2_9036978_9037461_-	pfam04306, DUF456, Protein of unknown function (DUF456)	NA|327aa|down_5|NZ_CP041650.2_9037497_9038478_-	COG1378, COG1378, Predicted transcriptional regulators [Transcription]	NA|643aa|down_6|NZ_CP041650.2_9038953_9040882_+	pfam13672, PP2C_2, Protein phosphatase 2C	NA|581aa|down_7|NZ_CP041650.2_9040963_9042706_+	PRK06546, PRK06546, pyruvate dehydrogenase; Provisional	NA|141aa|down_8|NZ_CP041650.2_9043245_9043668_+	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|351aa|down_9|NZ_CP041650.2_9043732_9044785_-	pfam10935, DUF2637, Protein of unknown function (DUF2637)
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	20	10062753-10062836	18	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CCCCGGAGTCCCGTGCCCGTGGCC	24	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA,NA	NA|404aa|up_9|NZ_CP041650.2_10047333_10048545_+	pfam01551, Peptidase_M23, Peptidase family M23	NA|248aa|up_8|NZ_CP041650.2_10050205_10050949_+	pfam11575, FhuF_C, FhuF 2Fe-2S C-terminal domain	NA|384aa|up_7|NZ_CP041650.2_10051030_10052182_+	TIGR02149, glgA_Coryne, glycogen synthase, Corynebacterium family	NA|407aa|up_6|NZ_CP041650.2_10052263_10053484_+	PRK00844, glgC, glucose-1-phosphate adenylyltransferase; Provisional	NA|869aa|up_5|NZ_CP041650.2_10053721_10056328_+	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]	NA|444aa|up_4|NZ_CP041650.2_10056590_10057922_+	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT	NA|484aa|up_3|NZ_CP041650.2_10058119_10059571_+	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|539aa|up_2|NZ_CP041650.2_10059579_10061196_-	pfam00144, Beta-lactamase, Beta-lactamase	NA|267aa|up_1|NZ_CP041650.2_10061340_10062141_-	PRK07231, FabG-like, SDR family oxidoreductase	NA|152aa|up_0|NZ_CP041650.2_10062166_10062622_-	TIGR03276, Phn-HD, phosphonate degradation operons associated HDIG domain protein	NA|161aa|down_0|NZ_CP041650.2_10064773_10065256_+	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]	NA|448aa|down_1|NZ_CP041650.2_10065285_10066629_-	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]	NA|780aa|down_2|NZ_CP041650.2_10066881_10069221_+	pfam01120, Alpha_L_fucos, Alpha-L-fucosidase	NA|632aa|down_3|NZ_CP041650.2_10069213_10071109_+	cd06564, GH20_DspB_LnbB-like, Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins	NA|511aa|down_4|NZ_CP041650.2_10071128_10072661_+	COG3669, COG3669, Alpha-L-fucosidase [Carbohydrate transport and metabolism]	NA|348aa|down_5|NZ_CP041650.2_10072764_10073808_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|431aa|down_6|NZ_CP041650.2_10074028_10075321_+	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|299aa|down_7|NZ_CP041650.2_10075329_10076226_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|303aa|down_8|NZ_CP041650.2_10076279_10077188_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|416aa|down_9|NZ_CP041650.2_10077237_10078485_+	COG2730, BglC, Endoglucanase [Carbohydrate transport and metabolism]
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	21	10529895-10529978	19	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CCGCCCGCTGGTACGAGGACCAGGTCG	27	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA|226aa|up_8|NZ_CP041650.2_10514811_10515489_-,NA|89aa|up_3|NZ_CP041650.2_10524890_10525157_-,NA|46aa|down_0|NZ_CP041650.2_10530683_10530821_-,NA|64aa|down_4|NZ_CP041650.2_10534800_10534992_-,NA|62aa|down_6|NZ_CP041650.2_10538847_10539033_-,NA|46aa|down_7|NZ_CP041650.2_10539036_10539174_-,NA|46aa|down_8|NZ_CP041650.2_10539280_10539418_-,NA|130aa|down_9|NZ_CP041650.2_10540282_10540672_+	NA|140aa|up_9|NZ_CP041650.2_10514057_10514477_-	pfam13586, DDE_Tnp_1_2, Transposase DDE domain	NA|226aa|up_8|NZ_CP041650.2_10514811_10515489_-	NA	NA|883aa|up_7|NZ_CP041650.2_10517561_10520210_+	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases	NA|39aa|up_6|NZ_CP041650.2_10520291_10520408_+	NF033212, SapB_AmfS_lanti, SapB/AmfS family lantipeptide	NA|571aa|up_5|NZ_CP041650.2_10520614_10522327_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|203aa|up_4|NZ_CP041650.2_10524072_10524681_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|89aa|up_3|NZ_CP041650.2_10524890_10525157_-	NA	NA|548aa|up_2|NZ_CP041650.2_10525384_10527028_+	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|69aa|up_1|NZ_CP041650.2_10528255_10528462_+	PHA01513, mnt, Mnt	NA|232aa|up_0|NZ_CP041650.2_10528659_10529355_-	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|46aa|down_0|NZ_CP041650.2_10530683_10530821_-	NA	NA|160aa|down_1|NZ_CP041650.2_10532462_10532942_-	COG1846, MarR, Transcriptional regulators [Transcription]	NA|300aa|down_2|NZ_CP041650.2_10533024_10533924_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|80aa|down_3|NZ_CP041650.2_10534475_10534715_+	pfam17227, DUF5302, Family of unknown function (DUF5302)	NA|64aa|down_4|NZ_CP041650.2_10534800_10534992_-	NA	NA|99aa|down_5|NZ_CP041650.2_10537707_10538004_-	pfam14040, DNase_NucA_NucB, Deoxyribonuclease NucA/NucB	NA|62aa|down_6|NZ_CP041650.2_10538847_10539033_-	NA	NA|46aa|down_7|NZ_CP041650.2_10539036_10539174_-	NA	NA|46aa|down_8|NZ_CP041650.2_10539280_10539418_-	NA	NA|130aa|down_9|NZ_CP041650.2_10540282_10540672_+	NA
GCF_007113405.2_ASM711340v2	NZ_CP041650	Streptomyces sp. RLB1-8 chromosome, complete genome	22	11558821-11559032	20	CRISPRCasFinder	no		DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	Orphan	CGACCCACCTCCGCTGGCGCGGAGAGCAC	29	0	0	NA	NA	NA	3	3	Orphan	DEDDh,c2c10_CAS-V-U3,c2c9_V-U4,WYL,cas14j,csa3,Cas14u_CAS-V,RT,cas4,Cas9_archaeal,cas14i,DinG	NA,NA|50aa|down_4|NZ_CP041650.2_11563694_11563844_+	NA|212aa|up_9|NZ_CP041650.2_11547080_11547716_-	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit	NA|261aa|up_8|NZ_CP041650.2_11547712_11548495_-	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]	NA|325aa|up_7|NZ_CP041650.2_11549280_11550255_-	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family	NA|321aa|up_6|NZ_CP041650.2_11550343_11551306_-	cd07239, BphC5-RK37_C_like, C-terminal, catalytic domain of BphC5 (2,3-dihydroxybiphenyl 1,2-dioxygenase)	NA|345aa|up_5|NZ_CP041650.2_11551317_11552352_-	pfam04909, Amidohydro_2, Amidohydrolase	NA|390aa|up_4|NZ_CP041650.2_11552348_11553518_-	PRK06847, PRK06847, hypothetical protein; Provisional	NA|327aa|up_3|NZ_CP041650.2_11553638_11554619_-	pfam04199, Cyclase, Putative cyclase	NA|333aa|up_2|NZ_CP041650.2_11554615_11555614_-	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family	NA|315aa|up_1|NZ_CP041650.2_11555749_11556694_+	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold	NA|428aa|up_0|NZ_CP041650.2_11556806_11558090_+	cd17473, MFS_arabinose_efflux_permease_like, Putative arabinose efflux permease family transporters of the Major Facilitator Superfamily	NA|339aa|down_0|NZ_CP041650.2_11559195_11560212_-	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional	NA|289aa|down_1|NZ_CP041650.2_11560766_11561633_+	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|297aa|down_2|NZ_CP041650.2_11561832_11562723_+	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease	NA|221aa|down_3|NZ_CP041650.2_11562877_11563540_-	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family	NA|50aa|down_4|NZ_CP041650.2_11563694_11563844_+	NA	NA|82aa|down_5|NZ_CP041650.2_11563995_11564241_-	pfam10049, DUF2283, Protein of unknown function (DUF2283)	NA|328aa|down_6|NZ_CP041650.2_11565773_11566757_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|540aa|down_7|NZ_CP041650.2_11567369_11568989_+	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases	NA|207aa|down_8|NZ_CP041650.2_11569645_11570266_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|479aa|down_9|NZ_CP041650.2_11570701_11572138_+	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase  AldA-like
