assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_004802635.2_ASM480263v2	NZ_CP046052	Methylocystis heyeri strain H2 chromosome, complete genome	1	2047628-2047715	1	CRISPRCasFinder	no		csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	Orphan	CGAGCGGACGTTCCGTCCGCCCGGAAAGCG	30	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	NA,NA|115aa|down_2|NZ_CP046052.1_2051827_2052172_+,NA|68aa|down_3|NZ_CP046052.1_2052228_2052432_+	NA|94aa|up_9|NZ_CP046052.1_2038271_2038553_+	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only]	NA|108aa|up_8|NZ_CP046052.1_2038576_2038900_+	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family	NA|254aa|up_7|NZ_CP046052.1_2039194_2039956_+	TIGR01428, Haloacetate_dehalogenase, 2-haloalkanoic acid dehalogenase, type II	NA|236aa|up_6|NZ_CP046052.1_2040024_2040732_+	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism]	NA|463aa|up_5|NZ_CP046052.1_2040737_2042126_-	cd01031, EriC, ClC chloride channel EriC	NA|225aa|up_4|NZ_CP046052.1_2042205_2042880_-	cd07512, HAD_PGPase, haloacid dehalogenase-like superfamily phosphoglycolate phosphatase, similar to Rhodobacter sphaeroides CbbZ	NA|595aa|up_3|NZ_CP046052.1_2043264_2045049_-	PRK00476, aspS, aspartyl-tRNA synthetase; Validated	NA|64aa|up_2|NZ_CP046052.1_2045500_2045692_-	pfam06698, DUF1192, Protein of unknown function (DUF1192)	NA|299aa|up_1|NZ_CP046052.1_2045731_2046628_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|194aa|up_0|NZ_CP046052.1_2046881_2047463_+	COG3247, HdeD, Uncharacterized conserved protein [Function unknown]	NA|894aa|down_0|NZ_CP046052.1_2047865_2050547_+	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional	NA|134aa|down_1|NZ_CP046052.1_2051314_2051716_-	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|115aa|down_2|NZ_CP046052.1_2051827_2052172_+	NA	NA|68aa|down_3|NZ_CP046052.1_2052228_2052432_+	NA	NA|356aa|down_4|NZ_CP046052.1_2052731_2053799_-	cd03814, GT4-like, glycosyltransferase family 4 proteins	NA|270aa|down_5|NZ_CP046052.1_2053798_2054608_-	COG2908, COG2908, Uncharacterized protein conserved in bacteria [Function unknown]	NA|206aa|down_6|NZ_CP046052.1_2055155_2055773_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|275aa|down_7|NZ_CP046052.1_2056095_2056920_+	pfam13403, Hint_2, Hint domain	NA|403aa|down_8|NZ_CP046052.1_2057176_2058385_+	cd17335, MFS_MFSD6, Major facilitator superfamily domain-containing protein 6	NA|197aa|down_9|NZ_CP046052.1_2058387_2058978_-	COG1376, ErfK, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_004802635.2_ASM480263v2	NZ_CP046052	Methylocystis heyeri strain H2 chromosome, complete genome	2	2421768-2421853	2	CRISPRCasFinder	no		csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	Orphan	CGTCCACTTCGGCTGGAGACGCTCT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	NA|577aa|up_6|NZ_CP046052.1_2412310_2414041_+,NA|271aa|up_3|NZ_CP046052.1_2417558_2418371_-,NA	NA|804aa|up_9|NZ_CP046052.1_2407977_2410389_+	TIGR02517, Putative_type_II_secretion_system_protein_D, type II secretion system protein D	NA|166aa|up_8|NZ_CP046052.1_2410722_2411220_-	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G	NA|215aa|up_7|NZ_CP046052.1_2411449_2412094_+	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]	NA|577aa|up_6|NZ_CP046052.1_2412310_2414041_+	NA	NA|701aa|up_5|NZ_CP046052.1_2414267_2416370_+	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional	NA|356aa|up_4|NZ_CP046052.1_2416506_2417574_+	cd01902, Ntn_CGH, Choloylglycine hydrolase (CGH) is a bile salt-modifying enzyme that hydrolyzes non-peptide carbon-nitrogen bonds in choloylglycine and choloyltaurine, both of which are present in bile	NA|271aa|up_3|NZ_CP046052.1_2417558_2418371_-	NA	NA|405aa|up_2|NZ_CP046052.1_2418402_2419617_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|296aa|up_1|NZ_CP046052.1_2419781_2420669_+	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH)	NA|321aa|up_0|NZ_CP046052.1_2420691_2421654_+	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]	NA|249aa|down_0|NZ_CP046052.1_2423462_2424209_-	COG4649, COG4649, Uncharacterized protein conserved in bacteria [Function unknown]	NA|543aa|down_1|NZ_CP046052.1_2424610_2426239_+	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed	NA|145aa|down_2|NZ_CP046052.1_2426515_2426950_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|397aa|down_3|NZ_CP046052.1_2427213_2428404_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|232aa|down_4|NZ_CP046052.1_2428427_2429123_+	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed	NA|303aa|down_5|NZ_CP046052.1_2429299_2430208_+	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]	NA|224aa|down_6|NZ_CP046052.1_2430246_2430918_+	COG2802, COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only]	NA|72aa|down_7|NZ_CP046052.1_2430996_2431212_+	COG2835, COG2835, Uncharacterized conserved protein [Function unknown]	NA|287aa|down_8|NZ_CP046052.1_2431218_2432079_+	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism]	NA|113aa|down_9|NZ_CP046052.1_2432635_2432974_+	pfam00543, P-II, Nitrogen regulatory protein P-II
GCF_004802635.2_ASM480263v2	NZ_CP046052	Methylocystis heyeri strain H2 chromosome, complete genome	3	3517550-3518311	3,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas9,cas1,cas2	csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	 or Type II-C?,Type II-A, Type II-B,Type II-C,Type II-B	GCTGCGGCTTGCGACCGCTTCTCGGTTCACTACAAT,GCTGCGGCTTGCGACCGCTTCTCGGTTCACTACAAT,GCTGCGGCTTGCGACCGCTTCTCGGTTCACTACAAT	36,36,36	1	1	3518180-3518209	NZ_CP046052.1_3093686-3093657	NA:NA:NA	11,11,7	11	orTypeII-C?,TypeII-A,TypeII-B,TypeII-C,TypeII-B	csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	NA,NA	NA|574aa|up_9|NZ_CP046052.1_3504658_3506380_-	cd03468, PolY_like, DNA Polymerase Y-family	NA|290aa|up_8|NZ_CP046052.1_3506306_3507176_-	COG4544, COG4544, Uncharacterized conserved protein [Function unknown]	NA|214aa|up_7|NZ_CP046052.1_3507406_3508048_-	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]	NA|144aa|up_6|NZ_CP046052.1_3508210_3508642_+	TIGR04401, conserved_hypothetical_protein, twin-arginine translocation signal/Cys-rich four helix bundle protein	NA|192aa|up_5|NZ_CP046052.1_3508688_3509264_-	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate	NA|220aa|up_4|NZ_CP046052.1_3509260_3509920_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|464aa|up_3|NZ_CP046052.1_3509960_3511352_+	PRK00855, PRK00855, argininosuccinate lyase; Provisional	NA|153aa|up_2|NZ_CP046052.1_3511455_3511914_-	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea	NA|1213aa|up_1|NZ_CP046052.1_3512147_3515786_-	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]	NA|479aa|up_0|NZ_CP046052.1_3516043_3517480_+	COG5310, COG5310, Homospermidine synthase [Secondary metabolites biosynthesis, transport, and catabolism]	cas9|1088aa|down_0|NZ_CP046052.1_3519109_3522373_+	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9	cas1|311aa|down_1|NZ_CP046052.1_3522379_3523312_+	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI	cas2|102aa|down_2|NZ_CP046052.1_3523364_3523670_+	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms]	NA|114aa|down_3|NZ_CP046052.1_3523893_3524235_-	TIGR00365, TIGR00365, monothiol glutaredoxin, Grx4 family	NA|75aa|down_4|NZ_CP046052.1_3524309_3524534_-	COG0271, BolA, Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]	NA|752aa|down_5|NZ_CP046052.1_3524520_3526776_-	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL	NA|310aa|down_6|NZ_CP046052.1_3527071_3528001_+	COG3047, OmpW, Outer membrane protein W [Cell envelope biogenesis, outer membrane]	NA|140aa|down_7|NZ_CP046052.1_3528597_3529017_-	pfam14216, DUF4326, Domain of unknown function (DUF4326)	NA|369aa|down_8|NZ_CP046052.1_3529164_3530271_-	PRK01278, argD, acetylornithine transaminase protein; Provisional	NA|290aa|down_9|NZ_CP046052.1_3530684_3531554_-	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein
GCF_004802635.2_ASM480263v2	NZ_CP046052	Methylocystis heyeri strain H2 chromosome, complete genome	4	4456880-4456964	4	CRISPRCasFinder	no		csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	Orphan	CGCGTGAAAACAAAAACTTAGAG	23	1	2	4456903-4456941|4456903-4456941	NZ_CP046052.1_3891258-3891220|NZ_CP046052.1_3948676-3948714	NA	1	1	Orphan	csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	NA|77aa|up_4|NZ_CP046052.1_4452044_4452275_-,NA|76aa|down_2|NZ_CP046052.1_4458944_4459172_+	NA|414aa|up_9|NZ_CP046052.1_4448650_4449892_-	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional	NA|150aa|up_8|NZ_CP046052.1_4449902_4450352_-	COG0848, ExbD, Biopolymer transport protein [Intracellular trafficking and secretion]	NA|245aa|up_7|NZ_CP046052.1_4450373_4451108_-	TIGR02796, Protein_TolQ, TolQ protein	NA|139aa|up_6|NZ_CP046052.1_4451344_4451761_-	TIGR02799, Acyl-CoA_thioesterase_YbgC, tol-pal system-associated acyl-CoA thioesterase	NA|97aa|up_5|NZ_CP046052.1_4451757_4452048_-	COG3668, ParE, Plasmid stabilization system protein [General function prediction only]	NA|77aa|up_4|NZ_CP046052.1_4452044_4452275_-	NA	NA|349aa|up_3|NZ_CP046052.1_4452327_4453374_-	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB	NA|556aa|up_2|NZ_CP046052.1_4453612_4455280_+	cd16025, PAS_like, Bacterial Arylsulfatase of Pseudomonas aeruginosa and related proteins	NA|161aa|up_1|NZ_CP046052.1_4455397_4455880_+	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated	NA|242aa|up_0|NZ_CP046052.1_4455846_4456572_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|154aa|down_0|NZ_CP046052.1_4456992_4457454_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|353aa|down_1|NZ_CP046052.1_4457573_4458632_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|76aa|down_2|NZ_CP046052.1_4458944_4459172_+	NA	NA|375aa|down_3|NZ_CP046052.1_4459521_4460646_-	pfam01906, YbjQ_1, Putative heavy-metal-binding	NA|354aa|down_4|NZ_CP046052.1_4460795_4461857_+	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]	NA|304aa|down_5|NZ_CP046052.1_4461853_4462765_+	PRK10683, PRK10683, putrescine transporter subunit: membrane component of ABC superfamily; Provisional	NA|266aa|down_6|NZ_CP046052.1_4462761_4463559_+	PRK10592, PRK10592, putrescine transporter subunit: membrane component of ABC superfamily; Provisional	NA|386aa|down_7|NZ_CP046052.1_4463734_4464892_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|231aa|down_8|NZ_CP046052.1_4464898_4465591_+	PRK09087, PRK09087, hypothetical protein; Validated	NA|744aa|down_9|NZ_CP046052.1_4465658_4467890_+	PRK05443, PRK05443, polyphosphate kinase; Provisional
GCF_004802635.2_ASM480263v2	NZ_CP046052	Methylocystis heyeri strain H2 chromosome, complete genome	5	4480988-4481075	5	CRISPRCasFinder	no		csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	Orphan	GCGGTTTTTGGATAAGAACATGCCTGG	27	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,cas9,cas1,cas2,WYL	NA,NA|202aa|down_7|NZ_CP046052.1_4490090_4490696_-,NA|97aa|down_8|NZ_CP046052.1_4490819_4491110_+	NA|226aa|up_9|NZ_CP046052.1_4470734_4471412_+	COG5385, COG5385, Uncharacterized protein conserved in bacteria [Function unknown]	NA|850aa|up_8|NZ_CP046052.1_4471646_4474196_+	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]	NA|183aa|up_7|NZ_CP046052.1_4474192_4474741_+	pfam01584, CheW, CheW-like domain	NA|122aa|up_6|NZ_CP046052.1_4474737_4475103_+	pfam00072, Response_reg, Response regulator receiver domain	NA|305aa|up_5|NZ_CP046052.1_4475167_4476082_+	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]	NA|234aa|up_4|NZ_CP046052.1_4476305_4477007_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|45aa|up_3|NZ_CP046052.1_4477822_4477957_+	pfam00468, Ribosomal_L34, Ribosomal protein L34	NA|143aa|up_2|NZ_CP046052.1_4477993_4478422_+	pfam00825, Ribonuclease_P, Ribonuclease P	NA|594aa|up_1|NZ_CP046052.1_4478418_4480200_+	PRK01318, PRK01318, membrane protein insertase; Provisional	NA|223aa|up_0|NZ_CP046052.1_4480272_4480941_+	PRK00454, engB, GTP-binding protein YsxC; Reviewed	NA|295aa|down_0|NZ_CP046052.1_4481156_4482041_+	PRK00942, PRK00942, acetylglutamate kinase; Provisional	NA|249aa|down_1|NZ_CP046052.1_4482049_4482796_+	cd02604, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to Saccharomyces cerevisiae Phm8p and Sdt1p	NA|172aa|down_2|NZ_CP046052.1_4482842_4483358_-	COG4907, COG4907, Predicted membrane protein [Function unknown]	NA|154aa|down_3|NZ_CP046052.1_4483948_4484410_-	PRK13258, PRK13258, 7-cyano-7-deazaguanine reductase; Provisional	NA|428aa|down_4|NZ_CP046052.1_4484552_4485836_+	PRK00077, eno, enolase; Provisional	NA|906aa|down_5|NZ_CP046052.1_4486318_4489036_+	PRK05729, valS, valyl-tRNA synthetase; Reviewed	NA|282aa|down_6|NZ_CP046052.1_4489179_4490025_+	pfam13406, SLT_2, Transglycosylase SLT domain	NA|202aa|down_7|NZ_CP046052.1_4490090_4490696_-	NA	NA|97aa|down_8|NZ_CP046052.1_4490819_4491110_+	NA	NA|254aa|down_9|NZ_CP046052.1_4491416_4492178_+	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins
