assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	1	117049-117140	1	CRISPRCasFinder	no		cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Orphan	CCACCTTTTTTACCTGCTTCAGATGC	26	0	0	NA	NA	NA	1	1	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA|70aa|up_8|NZ_CP027449.1_106298_106508_-,NA	NA|503aa|up_9|NZ_CP027449.1_104631_106140_-	PRK15419, PRK15419, sodium/proline symporter PutP	NA|70aa|up_8|NZ_CP027449.1_106298_106508_-	NA	NA|213aa|up_7|NZ_CP027449.1_110565_111204_-	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional	NA|364aa|up_6|NZ_CP027449.1_111491_112583_+	TIGR03612, RutA, pyrimidine utilization protein A	NA|231aa|up_5|NZ_CP027449.1_112582_113275_+	TIGR03614, RutB, pyrimidine utilization protein B	NA|129aa|up_4|NZ_CP027449.1_113286_113673_+	TIGR03610, RutC, pyrimidine utilization protein C	NA|267aa|up_3|NZ_CP027449.1_113680_114481_+	TIGR03611, RutD, pyrimidine utilization protein D	NA|197aa|up_2|NZ_CP027449.1_114490_115081_+	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|165aa|up_1|NZ_CP027449.1_115091_115586_+	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F	NA|443aa|up_0|NZ_CP027449.1_115606_116935_+	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|199aa|down_0|NZ_CP027449.1_117563_118160_+	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|76aa|down_1|NZ_CP027449.1_118180_118408_+	PRK10174, PRK10174, hypothetical protein; Provisional	NA|414aa|down_2|NZ_CP027449.1_118445_119687_-	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional	NA|419aa|down_3|NZ_CP027449.1_119979_121236_-	PRK09784, PRK09784, YccE family protein	NA|307aa|down_4|NZ_CP027449.1_121496_122417_+	PRK10266, PRK10266, curved DNA-binding protein	NA|102aa|down_5|NZ_CP027449.1_122416_122722_+	PRK10265, PRK10265, chaperone modulator CbpM	NA|200aa|down_6|NZ_CP027449.1_122814_123414_-	PRK04976, torD, chaperone protein TorD; Validated	NA|849aa|down_7|NZ_CP027449.1_123410_125957_-	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA	NA|391aa|down_8|NZ_CP027449.1_125956_127129_-	PRK15032, PRK15032, pentaheme c-type cytochrome TorC	NA|231aa|down_9|NZ_CP027449.1_127258_127951_+	PRK10766, PRK10766, two-component system response regulator TorR
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	2	259860-260187	2,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas6f,cas7f,cas5f,cas8f,cas3f,cas1	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Type I-F	TTTCTAAGCTGCCTGTACGGCAGTGAAC,TTTCTAAGCTGCCTGTACGGCAGTGAAC,TTTCTAAGCTGCCTGTACGGCAGTGAAC	28,28,28	0	0	NA	NA	I-F:I-F:I-F	5,5,4	5	TypeI-F	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA	NA|431aa|up_9|NZ_CP027449.1_245177_246470_-	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional	NA|448aa|up_8|NZ_CP027449.1_246560_247904_-	PRK13342, PRK13342, recombination factor protein RarA; Reviewed	NA|204aa|up_7|NZ_CP027449.1_247914_248526_-	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA	NA|1356aa|up_6|NZ_CP027449.1_248680_252748_-	PRK10263, PRK10263, DNA translocase FtsK; Provisional	NA|165aa|up_5|NZ_CP027449.1_252882_253377_-	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp	NA|322aa|up_4|NZ_CP027449.1_253921_254887_+	PRK10262, PRK10262, thioredoxin reductase; Provisional	NA|589aa|up_3|NZ_CP027449.1_255009_256776_+	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed	NA|574aa|up_2|NZ_CP027449.1_256776_258498_+	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed	NA|235aa|up_1|NZ_CP027449.1_258539_259244_+	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed	NA|73aa|up_0|NZ_CP027449.1_259528_259747_+	PRK00276, infA, translation initiation factor IF-1; Validated	cas6f|185aa|down_0|NZ_CP027449.1_260729_261284_-	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f	cas7f|334aa|down_1|NZ_CP027449.1_261294_262296_-	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3)	cas5f|308aa|down_2|NZ_CP027449.1_262306_263230_-	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2)	cas8f|436aa|down_3|NZ_CP027449.1_263226_264534_-	cd09735, Csy1_I-F, CRISPR/Cas system-associated protein Csy1	cas3f|1078aa|down_4|NZ_CP027449.1_264864_268098_-	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST	cas1|328aa|down_5|NZ_CP027449.1_268094_269078_-	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST	NA|759aa|down_6|NZ_CP027449.1_270330_272607_-	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional	NA|107aa|down_7|NZ_CP027449.1_272637_272958_-	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed	NA|75aa|down_8|NZ_CP027449.1_273280_273505_+	PRK09937, PRK09937, cold shock-like protein CspD	NA|649aa|down_9|NZ_CP027449.1_273577_275524_-	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	3	269251-270118	3,2,2	CRISPRCasFinder,CRT,PILER-CR	no	cas6f,cas7f,cas5f,cas8f,cas3f,cas1	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Type I-F	TTTCTAAGCTGCCTGTACGGCAGTGAAC,TTTCTAAGCTGCCTGTACGGCAGTGAAC,TTTCTAAGCTGCCTGTACGGCAGTGAAC	28,28,28	0	0	NA	NA	I-F:I-F:I-F	14,14,13	14	TypeI-F	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA	NA|589aa|up_9|NZ_CP027449.1_255009_256776_+	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed	NA|574aa|up_8|NZ_CP027449.1_256776_258498_+	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed	NA|235aa|up_7|NZ_CP027449.1_258539_259244_+	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed	NA|73aa|up_6|NZ_CP027449.1_259528_259747_+	PRK00276, infA, translation initiation factor IF-1; Validated	cas6f|185aa|up_5|NZ_CP027449.1_260729_261284_-	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f	cas7f|334aa|up_4|NZ_CP027449.1_261294_262296_-	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3)	cas5f|308aa|up_3|NZ_CP027449.1_262306_263230_-	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2)	cas8f|436aa|up_2|NZ_CP027449.1_263226_264534_-	cd09735, Csy1_I-F, CRISPR/Cas system-associated protein Csy1	cas3f|1078aa|up_1|NZ_CP027449.1_264864_268098_-	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST	cas1|328aa|up_0|NZ_CP027449.1_268094_269078_-	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST	NA|759aa|down_0|NZ_CP027449.1_270330_272607_-	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional	NA|107aa|down_1|NZ_CP027449.1_272637_272958_-	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed	NA|75aa|down_2|NZ_CP027449.1_273280_273505_+	PRK09937, PRK09937, cold shock-like protein CspD	NA|649aa|down_3|NZ_CP027449.1_273577_275524_-	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB	NA|372aa|down_4|NZ_CP027449.1_275520_276636_-	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional	NA|319aa|down_5|NZ_CP027449.1_276786_277743_+	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown]	NA|553aa|down_6|NZ_CP027449.1_277739_279398_-	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]	NA|232aa|down_7|NZ_CP027449.1_279823_280519_+	PRK05420, PRK05420, aquaporin Z; Provisional	NA|300aa|down_8|NZ_CP027449.1_281013_281913_+	COG2431, COG2431, Predicted membrane protein [Function unknown]	NA|551aa|down_9|NZ_CP027449.1_282056_283709_+	PRK05290, PRK05290, hybrid cluster protein; Provisional
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	4	427129-427273	4	CRISPRCasFinder	no		cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Orphan	GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	52	0	0	NA	NA	NA	1	1	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA	NA|171aa|up_9|NZ_CP027449.1_414492_415005_-	TIGR02667, Molybdenum_cofactor_biosynthesis_protein_B	NA|330aa|up_8|NZ_CP027449.1_415026_416016_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|303aa|up_7|NZ_CP027449.1_416412_417321_+	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related	NA|674aa|up_6|NZ_CP027449.1_417512_419534_-	PRK05298, PRK05298, excinuclease ABC subunit UvrB	NA|226aa|up_5|NZ_CP027449.1_420112_420790_-	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD	NA|252aa|up_4|NZ_CP027449.1_420782_421538_-	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional	NA|385aa|up_3|NZ_CP027449.1_421524_422679_-	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed	NA|347aa|up_2|NZ_CP027449.1_422675_423716_-	PRK15108, PRK15108, biotin synthase; Provisional	NA|159aa|up_1|NZ_CP027449.1_425151_425628_+	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional	NA|428aa|up_0|NZ_CP027449.1_425779_427063_+	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase	NA|754aa|down_0|NZ_CP027449.1_427296_429558_-	PRK11413, PRK11413, putative hydratase; Provisional	NA|478aa|down_1|NZ_CP027449.1_429740_431174_-	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region	NA|351aa|down_2|NZ_CP027449.1_431249_432302_-	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase	NA|318aa|down_3|NZ_CP027449.1_432485_433439_+	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|332aa|down_4|NZ_CP027449.1_433479_434475_-	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional	NA|273aa|down_5|NZ_CP027449.1_434629_435448_+	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional	NA|353aa|down_6|NZ_CP027449.1_435448_436507_-	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC	NA|230aa|down_7|NZ_CP027449.1_436509_437199_-	PRK09421, modB, molybdate ABC transporter permease subunit	NA|258aa|down_8|NZ_CP027449.1_437198_437972_-	PRK10677, modA, molybdate transporter periplasmic protein; Provisional	NA|50aa|down_9|NZ_CP027449.1_438138_438288_-	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	5	889396-889540	5	CRISPRCasFinder	no		cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Orphan	TAAACCGTAGGCCTGATAAGACGCGCAAAGCGTCGCATCAGGCAT	45	0	0	NA	NA	NA	1	1	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA	NA|276aa|up_9|NZ_CP027449.1_880410_881238_-	PRK10160, PRK10160, taurine ABC transporter permease TauC	NA|256aa|up_8|NZ_CP027449.1_881234_882002_-	PRK11248, tauB, taurine ABC transporter ATP-binding subunit	NA|321aa|up_7|NZ_CP027449.1_882014_882977_-	PRK11480, tauA, taurine transporter substrate binding subunit; Provisional	NA|224aa|up_6|NZ_CP027449.1_883593_884265_+	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown]	NA|399aa|up_5|NZ_CP027449.1_884274_885471_+	COG1215, COG1215, Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]	NA|194aa|up_4|NZ_CP027449.1_885448_886030_+	cd05636, LbH_G1P_TT_C_like, Putative glucose-1-phosphate thymidylyltransferase, C-terminal Left-handed parallel beta-Helix (LbH) domain: Proteins in this family show simlarity to glucose-1-phosphate adenylyltransferases in that they contain N-terminal catalytic domains that resemble a dinucleotide-binding Rossmann fold and C-terminal LbH fold domains	NA|258aa|up_3|NZ_CP027449.1_886031_886805_+	TIGR04390, hypothetical_protein, outer membrane protein, YaiO family	NA|92aa|up_2|NZ_CP027449.1_886990_887266_+	PRK11352, PRK11352, formaldehyde-responsive transcriptional repressor FrmR	NA|370aa|up_1|NZ_CP027449.1_887300_888410_+	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases	NA|278aa|up_0|NZ_CP027449.1_888502_889336_+	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase	NA|180aa|down_0|NZ_CP027449.1_889561_890101_-	COG3122, COG3122, Uncharacterized protein conserved in bacteria [Function unknown]	NA|404aa|down_1|NZ_CP027449.1_890202_891414_-	PRK11551, PRK11551, putative 3-hydroxyphenylpropionic transporter MhpT; Provisional	NA|338aa|down_2|NZ_CP027449.1_891589_892603_-	PRK08195, PRK08195, 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated	NA|317aa|down_3|NZ_CP027449.1_892599_893550_-	PRK08300, PRK08300, acetaldehyde dehydrogenase; Validated	NA|270aa|down_4|NZ_CP027449.1_893546_894356_-	PRK11342, mhpD, 2-keto-4-pentenoate hydratase; Provisional	NA|289aa|down_5|NZ_CP027449.1_894365_895232_-	TIGR03343, 2-hydroxy-6-oxo-6-phenylhexa-24-dienoate_hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase	NA|315aa|down_6|NZ_CP027449.1_895249_896194_-	cd07365, MhpB_like, Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate	NA|555aa|down_7|NZ_CP027449.1_896195_897860_-	PRK06183, mhpA, bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase	NA|316aa|down_8|NZ_CP027449.1_897936_898884_+	PRK09834, PRK09834, DNA-binding transcriptional regulator	NA|361aa|down_9|NZ_CP027449.1_898960_900043_+	PRK09526, lacI, lac repressor; Reviewed
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	6	1208358-1208473	6	CRISPRCasFinder	no		cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Orphan	AACGCCTGATGCGACGCTGACGCGTCTTATC	31	0	0	NA	NA	NA	1	1	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA	NA|393aa|up_9|NZ_CP027449.1_1196385_1197564_-	TIGR00899, Sugar_efflux_transporter_A, sugar efflux transporter	NA|44aa|up_8|NZ_CP027449.1_1197665_1197797_-	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT	NA|552aa|up_7|NZ_CP027449.1_1197885_1199541_+	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR	NA|328aa|up_6|NZ_CP027449.1_1199704_1200688_+	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional	NA|537aa|up_5|NZ_CP027449.1_1200663_1202274_+	PRK09433, thiP, thiamine transporter membrane protein; Reviewed	NA|233aa|up_4|NZ_CP027449.1_1202257_1202956_+	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ	NA|255aa|up_3|NZ_CP027449.1_1203057_1203822_-	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|293aa|up_2|NZ_CP027449.1_1203907_1204786_-	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC	NA|567aa|up_1|NZ_CP027449.1_1205124_1206825_+	PRK04123, PRK04123, ribulokinase; Provisional	NA|501aa|up_0|NZ_CP027449.1_1206835_1208338_+	PRK02929, PRK02929, L-arabinose isomerase; Provisional	NA|232aa|down_0|NZ_CP027449.1_1208537_1209233_+	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD	NA|784aa|down_1|NZ_CP027449.1_1209307_1211659_+	PRK05762, PRK05762, DNA polymerase II; Reviewed	NA|220aa|down_2|NZ_CP027449.1_1214742_1215402_+	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA|272aa|down_3|NZ_CP027449.1_1215518_1216334_-	PRK09430, djlA, co-chaperone DjlA	NA|785aa|down_4|NZ_CP027449.1_1216588_1218943_+	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional	NA|429aa|down_5|NZ_CP027449.1_1218995_1220282_+	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional	NA|330aa|down_6|NZ_CP027449.1_1220281_1221271_+	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed	NA|274aa|down_7|NZ_CP027449.1_1221267_1222089_+	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA	NA|126aa|down_8|NZ_CP027449.1_1222091_1222469_+	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed	NA|283aa|down_9|NZ_CP027449.1_1222475_1223324_+	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	7	1232743-1232875	3	PILER-CR	no		cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Orphan	ATCACCAATATTGAAAA	17	0	0	NA	NA	NA	2	2	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA|156aa|up_9|NZ_CP027449.1_1223983_1224451_+,NA	NA|156aa|up_9|NZ_CP027449.1_1223983_1224451_+	NA	NA|60aa|up_8|NZ_CP027449.1_1224549_1224729_-	pfam07362, CcdA, Post-segregation antitoxin CcdA	NA|160aa|up_7|NZ_CP027449.1_1224749_1225229_-	PRK10769, folA, type 3 dihydrofolate reductase	NA|621aa|up_6|NZ_CP027449.1_1225421_1227284_-	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional	NA|177aa|up_5|NZ_CP027449.1_1227276_1227807_-	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF	NA|444aa|up_4|NZ_CP027449.1_1227914_1229246_-	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily	NA|96aa|up_3|NZ_CP027449.1_1229304_1229592_-	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional	NA|429aa|up_2|NZ_CP027449.1_1229588_1230875_-	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional	NA|314aa|up_1|NZ_CP027449.1_1230925_1231867_-	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein	NA|257aa|up_0|NZ_CP027449.1_1231881_1232652_-	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed	NA|505aa|down_0|NZ_CP027449.1_1233125_1234640_+	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter	NA|381aa|down_1|NZ_CP027449.1_1234670_1235813_+	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated	NA|406aa|down_2|NZ_CP027449.1_1235941_1237159_+	PRK03525, PRK03525, L-carnitine CoA-transferase	NA|518aa|down_3|NZ_CP027449.1_1237232_1238786_+	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated	NA|262aa|down_4|NZ_CP027449.1_1238894_1239680_+	PRK03580, PRK03580, crotonobetainyl-CoA hydratase	NA|197aa|down_5|NZ_CP027449.1_1239685_1240276_+	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional	NA|132aa|down_6|NZ_CP027449.1_1240361_1240757_-	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF	NA|1074aa|down_7|NZ_CP027449.1_1241017_1244239_-	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|383aa|down_8|NZ_CP027449.1_1244256_1245405_-	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit	NA|274aa|down_9|NZ_CP027449.1_1245860_1246682_-	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism]
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	8	2776763-2776880	7	CRISPRCasFinder	no		cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Orphan	TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	40	0	0	NA	NA	NA	1	1	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA|55aa|down_0|NZ_CP027449.1_2776953_2777118_-	NA|115aa|up_9|NZ_CP027449.1_2764484_2764829_-	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional	NA|313aa|up_8|NZ_CP027449.1_2765017_2765956_+	PRK10341, PRK10341, transcriptional regulator TdcA	NA|330aa|up_7|NZ_CP027449.1_2766054_2767044_+	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA|444aa|up_6|NZ_CP027449.1_2767065_2768397_+	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional	NA|403aa|up_5|NZ_CP027449.1_2768422_2769631_+	PRK12379, PRK12379, propionate kinase	NA|765aa|up_4|NZ_CP027449.1_2769664_2771959_+	cd01678, PFL1, Pyruvate formate lyase 1	NA|130aa|up_3|NZ_CP027449.1_2771972_2772362_+	PRK11401, PRK11401, enamine/imine deaminase	NA|455aa|up_2|NZ_CP027449.1_2772433_2773798_+	PRK15040, PRK15040, L-serine ammonia-lyase	NA|444aa|up_1|NZ_CP027449.1_2774072_2775404_+	TIGR00814, membrane_transport_protein_YhjV, serine transporter	NA|437aa|up_0|NZ_CP027449.1_2775431_2776742_+	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|55aa|down_0|NZ_CP027449.1_2776953_2777118_-	NA	NA|234aa|down_1|NZ_CP027449.1_2777140_2777842_-	COG1741, COG1741, Pirin-related protein [General function prediction only]	NA|299aa|down_2|NZ_CP027449.1_2777946_2778843_+	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold	NA|119aa|down_3|NZ_CP027449.1_2778893_2779250_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|122aa|down_4|NZ_CP027449.1_2779491_2779857_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|329aa|down_5|NZ_CP027449.1_2780149_2781136_-	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]	NA|161aa|down_6|NZ_CP027449.1_2781205_2781688_-	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|100aa|down_7|NZ_CP027449.1_2781783_2782083_-	pfam13997, YqjK, YqjK-like protein	NA|135aa|down_8|NZ_CP027449.1_2782072_2782477_-	COG5393, COG5393, Predicted membrane protein [Function unknown]	NA|102aa|down_9|NZ_CP027449.1_2782479_2782785_-	COG4575, ElaB, Uncharacterized conserved protein [Function unknown]
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	9	3257081-3257475	8,3,4	CRISPRCasFinder,CRT,PILER-CR	no	cas3	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Unclear	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTTCCCCGCGCCAGCGGGGATAAACCG	29,29,27	0	0	NA	NA	I-E:I-E:I-E	6,6,6	6	Unclear	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA|47aa|up_1|NZ_CP027449.1_3255790_3255931_-,NA	NA|434aa|up_9|NZ_CP027449.1_3246487_3247789_+	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	NA|745aa|up_8|NZ_CP027449.1_3247836_3250071_+	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|83aa|up_7|NZ_CP027449.1_3250148_3250397_+	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|112aa|up_6|NZ_CP027449.1_3250396_3250732_+	PRK09907, PRK09907, endoribonuclease MazF	NA|264aa|up_5|NZ_CP027449.1_3250802_3251594_+	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|546aa|up_4|NZ_CP027449.1_3251821_3253459_+	PRK05380, pyrG, CTP synthetase; Validated	NA|433aa|up_3|NZ_CP027449.1_3253546_3254845_+	PRK00077, eno, enolase; Provisional	NA|291aa|up_2|NZ_CP027449.1_3254904_3255777_-	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|47aa|up_1|NZ_CP027449.1_3255790_3255931_-	NA	NA|224aa|up_0|NZ_CP027449.1_3256069_3256741_+	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|493aa|down_0|NZ_CP027449.1_3258113_3259592_-	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|426aa|down_1|NZ_CP027449.1_3259618_3260896_-	cd06174, MFS, Major Facilitator Superfamily	NA|262aa|down_2|NZ_CP027449.1_3261214_3262000_+	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|485aa|down_3|NZ_CP027449.1_3262069_3263524_+	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|446aa|down_4|NZ_CP027449.1_3263617_3264955_+	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|260aa|down_5|NZ_CP027449.1_3264932_3265712_+	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|287aa|down_6|NZ_CP027449.1_3265708_3266569_+	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|192aa|down_7|NZ_CP027449.1_3266716_3267292_-	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|87aa|down_8|NZ_CP027449.1_3267308_3267569_-	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|424aa|down_9|NZ_CP027449.1_3267559_3268831_-	PRK10015, PRK10015, oxidoreductase; Provisional
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	10	3283174-3283690	5,9,4	PILER-CR,CRISPRCasFinder,CRT	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Type I-E	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	0	0	NA	NA	I-E:I-E:I-E	8,8,8	8	TypeI-E	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA	NA|245aa|up_9|NZ_CP027449.1_3273174_3273909_+	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|51aa|up_8|NZ_CP027449.1_3274173_3274326_+	pfam01848, HOK_GEF, Hok/gef family	cas3|900aa|up_7|NZ_CP027449.1_3274518_3277218_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas8e|521aa|up_6|NZ_CP027449.1_3277315_3278878_+	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1	cse2gr11|179aa|up_5|NZ_CP027449.1_3278874_3279411_+	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2	cas7|352aa|up_4|NZ_CP027449.1_3279422_3280478_+	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cas5|249aa|up_3|NZ_CP027449.1_3280488_3281235_+	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas6e|217aa|up_2|NZ_CP027449.1_3281216_3281867_+	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas1|307aa|up_1|NZ_CP027449.1_3281863_3282784_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|98aa|up_0|NZ_CP027449.1_3282783_3283077_+	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	NA|346aa|down_0|NZ_CP027449.1_3283771_3284809_-	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	NA|303aa|down_1|NZ_CP027449.1_3285060_3285969_+	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|476aa|down_2|NZ_CP027449.1_3285970_3287398_+	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|202aa|down_3|NZ_CP027449.1_3287397_3288003_+	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|108aa|down_4|NZ_CP027449.1_3288052_3288376_+	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|104aa|down_5|NZ_CP027449.1_3288569_3288881_+	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|237aa|down_6|NZ_CP027449.1_3288899_3289610_+	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|160aa|down_7|NZ_CP027449.1_3289609_3290089_+	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|350aa|down_8|NZ_CP027449.1_3290085_3291135_+	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|254aa|down_9|NZ_CP027449.1_3291115_3291877_+	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional
GCF_003018275.1_ASM301827v1	NZ_CP027449	Escherichia coli strain 2014C-3097 chromosome, complete genome	11	4396537-4396660	10	CRISPRCasFinder	no	DEDDh	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	Unclear	CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	43	0	0	NA	NA	NA	1	1	Orphan	cas3,cas6f,cas7f,cas5f,cas8f,cas3f,cas1,DinG,DEDDh,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas2,c2c9_V-U4	NA,NA|30aa|down_7|NZ_CP027449.1_4405556_4405646_+	NA|471aa|up_9|NZ_CP027449.1_4385990_4387403_-	PRK09206, PRK09206, pyruvate kinase PykF	NA|70aa|up_8|NZ_CP027449.1_4387959_4388169_+	PRK10292, PRK10292, fumarate hydratase FumD	NA|209aa|up_7|NZ_CP027449.1_4388624_4389251_+	PRK09898, PRK09898, ferredoxin-like protein	NA|701aa|up_6|NZ_CP027449.1_4389271_4391374_+	PRK09849, PRK09849, putative oxidoreductase; Provisional	NA|216aa|up_5|NZ_CP027449.1_4391377_4392025_+	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein	NA|223aa|up_4|NZ_CP027449.1_4392088_4392757_+	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein	NA|262aa|up_3|NZ_CP027449.1_4392753_4393539_+	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional	NA|271aa|up_2|NZ_CP027449.1_4393542_4394355_+	PRK09946, PRK09946, hypothetical protein; Provisional	NA|535aa|up_1|NZ_CP027449.1_4394366_4395971_-	PRK09897, PRK09897, FAD-NAD(P)-binding protein	NA|102aa|up_0|NZ_CP027449.1_4396096_4396402_-	PRK11118, PRK11118, putative monooxygenase; Provisional	NA|419aa|down_0|NZ_CP027449.1_4396974_4398231_+	PRK09945, PRK09945, hypothetical protein; Provisional	NA|458aa|down_1|NZ_CP027449.1_4398271_4399645_-	PRK01766, PRK01766, multidrug efflux protein; Reviewed	NA|214aa|down_2|NZ_CP027449.1_4399859_4400501_+	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional	NA|383aa|down_3|NZ_CP027449.1_4400540_4401689_-	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase	NA|404aa|down_4|NZ_CP027449.1_4401979_4403191_-	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter	NA|311aa|down_5|NZ_CP027449.1_4403303_4404236_+	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional	NA|342aa|down_6|NZ_CP027449.1_4404232_4405258_-	PRK10703, PRK10703, HTH-type transcriptional repressor PurR	NA|30aa|down_7|NZ_CP027449.1_4405556_4405646_+	NA	NA|390aa|down_8|NZ_CP027449.1_4405811_4406981_+	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|194aa|down_9|NZ_CP027449.1_4407126_4407708_-	PRK10543, PRK10543, superoxide dismutase [Fe]
