assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	1	776687-776831	1	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	TAAACCGTAGGCCTGATAAGACGCGCAAAGCGTCGCATCAGGCAT	45	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|321aa|up_9|NZ_CP027457.1_765064_766027_-	PRK11480, tauA, taurine transporter substrate binding subunit; Provisional	NA|210aa|up_8|NZ_CP027457.1_766329_766959_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|514aa|up_7|NZ_CP027457.1_766958_768500_+	COG3851, UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]	NA|439aa|up_6|NZ_CP027457.1_768572_769889_+	cd17488, MFS_UhpC, Membrane sensor protein UhpC of the Major Facilitator Superfamily of transporters	NA|344aa|up_5|NZ_CP027457.1_769885_770917_+	cd13544, PBP2_Fbp_like_1, Substrate binding domain of a putative ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily	NA|693aa|up_4|NZ_CP027457.1_770985_773064_+	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]	NA|349aa|up_3|NZ_CP027457.1_773075_774122_+	PRK11432, fbpC, ferric ABC transporter ATP-binding protein	NA|92aa|up_2|NZ_CP027457.1_774281_774557_+	PRK11352, PRK11352, formaldehyde-responsive transcriptional repressor FrmR	NA|370aa|up_1|NZ_CP027457.1_774591_775701_+	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases	NA|278aa|up_0|NZ_CP027457.1_775793_776627_+	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase	NA|180aa|down_0|NZ_CP027457.1_776852_777392_-	COG3122, COG3122, Uncharacterized protein conserved in bacteria [Function unknown]	NA|404aa|down_1|NZ_CP027457.1_777493_778705_-	PRK11551, PRK11551, putative 3-hydroxyphenylpropionic transporter MhpT; Provisional	NA|338aa|down_2|NZ_CP027457.1_779082_780096_-	PRK08195, PRK08195, 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated	NA|317aa|down_3|NZ_CP027457.1_780092_781043_-	PRK08300, PRK08300, acetaldehyde dehydrogenase; Validated	NA|270aa|down_4|NZ_CP027457.1_781039_781849_-	PRK11342, mhpD, 2-keto-4-pentenoate hydratase; Provisional	NA|289aa|down_5|NZ_CP027457.1_781858_782725_-	TIGR03343, 2-hydroxy-6-oxo-6-phenylhexa-24-dienoate_hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase	NA|315aa|down_6|NZ_CP027457.1_782742_783687_-	cd07365, MhpB_like, Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate	NA|555aa|down_7|NZ_CP027457.1_783688_785353_-	PRK06183, mhpA, bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase	NA|316aa|down_8|NZ_CP027457.1_785429_786377_+	PRK09834, PRK09834, DNA-binding transcriptional regulator	NA|361aa|down_9|NZ_CP027457.1_786453_787536_+	PRK09526, lacI, lac repressor; Reviewed
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	2	778864-779010	2	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	CGCGTCTTATCAGGCCTACAAATTCCCGCGCCATCCGTAGGCCGGA	46	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|514aa|up_9|NZ_CP027457.1_766958_768500_+	COG3851, UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]	NA|439aa|up_8|NZ_CP027457.1_768572_769889_+	cd17488, MFS_UhpC, Membrane sensor protein UhpC of the Major Facilitator Superfamily of transporters	NA|344aa|up_7|NZ_CP027457.1_769885_770917_+	cd13544, PBP2_Fbp_like_1, Substrate binding domain of a putative ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily	NA|693aa|up_6|NZ_CP027457.1_770985_773064_+	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]	NA|349aa|up_5|NZ_CP027457.1_773075_774122_+	PRK11432, fbpC, ferric ABC transporter ATP-binding protein	NA|92aa|up_4|NZ_CP027457.1_774281_774557_+	PRK11352, PRK11352, formaldehyde-responsive transcriptional repressor FrmR	NA|370aa|up_3|NZ_CP027457.1_774591_775701_+	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases	NA|278aa|up_2|NZ_CP027457.1_775793_776627_+	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase	NA|180aa|up_1|NZ_CP027457.1_776852_777392_-	COG3122, COG3122, Uncharacterized protein conserved in bacteria [Function unknown]	NA|404aa|up_0|NZ_CP027457.1_777493_778705_-	PRK11551, PRK11551, putative 3-hydroxyphenylpropionic transporter MhpT; Provisional	NA|338aa|down_0|NZ_CP027457.1_779082_780096_-	PRK08195, PRK08195, 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated	NA|317aa|down_1|NZ_CP027457.1_780092_781043_-	PRK08300, PRK08300, acetaldehyde dehydrogenase; Validated	NA|270aa|down_2|NZ_CP027457.1_781039_781849_-	PRK11342, mhpD, 2-keto-4-pentenoate hydratase; Provisional	NA|289aa|down_3|NZ_CP027457.1_781858_782725_-	TIGR03343, 2-hydroxy-6-oxo-6-phenylhexa-24-dienoate_hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase	NA|315aa|down_4|NZ_CP027457.1_782742_783687_-	cd07365, MhpB_like, Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate	NA|555aa|down_5|NZ_CP027457.1_783688_785353_-	PRK06183, mhpA, bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase	NA|316aa|down_6|NZ_CP027457.1_785429_786377_+	PRK09834, PRK09834, DNA-binding transcriptional regulator	NA|361aa|down_7|NZ_CP027457.1_786453_787536_+	PRK09526, lacI, lac repressor; Reviewed	NA|1025aa|down_8|NZ_CP027457.1_787658_790733_+	PRK09525, lacZ, beta-galactosidase	NA|418aa|down_9|NZ_CP027457.1_790784_792038_+	PRK09528, lacY, galactoside permease; Reviewed
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	3	1126966-1127097	1	PILER-CR	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	TCACCAATATTGAAAACG	18	0	0	NA	NA	NA	2	2	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|126aa|up_9|NZ_CP027457.1_1117666_1118044_+	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed	NA|281aa|up_8|NZ_CP027457.1_1118050_1118893_+	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical)	NA|160aa|up_7|NZ_CP027457.1_1118970_1119450_-	PRK10769, folA, type 3 dihydrofolate reductase	NA|621aa|up_6|NZ_CP027457.1_1119641_1121504_-	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional	NA|177aa|up_5|NZ_CP027457.1_1121496_1122027_-	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF	NA|444aa|up_4|NZ_CP027457.1_1122137_1123469_-	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily	NA|96aa|up_3|NZ_CP027457.1_1123526_1123814_-	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional	NA|429aa|up_2|NZ_CP027457.1_1123810_1125097_-	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional	NA|314aa|up_1|NZ_CP027457.1_1125147_1126089_-	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein	NA|257aa|up_0|NZ_CP027457.1_1126103_1126874_-	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed	NA|505aa|down_0|NZ_CP027457.1_1127347_1128862_+	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter	NA|381aa|down_1|NZ_CP027457.1_1128892_1130035_+	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated	NA|406aa|down_2|NZ_CP027457.1_1130163_1131381_+	PRK03525, PRK03525, L-carnitine CoA-transferase	NA|518aa|down_3|NZ_CP027457.1_1131454_1133008_+	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated	NA|262aa|down_4|NZ_CP027457.1_1133116_1133902_+	PRK03580, PRK03580, crotonobetainyl-CoA hydratase	NA|197aa|down_5|NZ_CP027457.1_1133907_1134498_+	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional	NA|132aa|down_6|NZ_CP027457.1_1134616_1135012_-	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF	NA|1074aa|down_7|NZ_CP027457.1_1135272_1138494_-	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|383aa|down_8|NZ_CP027457.1_1138511_1139660_-	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit	NA|274aa|down_9|NZ_CP027457.1_1140115_1140937_-	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism]
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	4	1303213-1303362	3	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	54	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA|679aa|up_5|NZ_CP027457.1_1293397_1295434_-,NA|591aa|down_6|NZ_CP027457.1_1310460_1312233_-	NA|327aa|up_9|NZ_CP027457.1_1290704_1291685_+	pfam03629, SASA, Carbohydrate esterase, sialic acid-specific acetylesterase	NA|41aa|up_8|NZ_CP027457.1_1291692_1291815_-	COG3183, COG3183, Predicted restriction endonuclease [Defense mechanisms]	NA|291aa|up_7|NZ_CP027457.1_1291896_1292769_+	COG3440, COG3440, Predicted restriction endonuclease [Defense mechanisms]	NA|60aa|up_6|NZ_CP027457.1_1292813_1292993_+	COG4930, COG4930, Predicted ATP-dependent Lon-type protease [Posttranslational modification, protein turnover, chaperones]	NA|679aa|up_5|NZ_CP027457.1_1293397_1295434_-	NA	NA|340aa|up_4|NZ_CP027457.1_1296403_1297423_+	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD)	NA|501aa|up_3|NZ_CP027457.1_1297552_1299055_+	pfam05872, DUF853, Bacterial protein of unknown function (DUF853)	NA|361aa|up_2|NZ_CP027457.1_1299215_1300298_-	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional	NA|367aa|up_1|NZ_CP027457.1_1300297_1301398_-	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional	NA|504aa|up_0|NZ_CP027457.1_1301664_1303176_+	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional	NA|148aa|down_0|NZ_CP027457.1_1303529_1303973_+	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated	NA|952aa|down_1|NZ_CP027457.1_1303972_1306828_+	PRK05729, valS, valyl-tRNA synthetase; Reviewed	NA|399aa|down_2|NZ_CP027457.1_1306883_1308080_-	COG4269, COG4269, Predicted membrane protein [Function unknown]	NA|168aa|down_3|NZ_CP027457.1_1308272_1308776_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|139aa|down_4|NZ_CP027457.1_1308821_1309238_-	PRK11191, PRK11191, ribonuclease E inhibitor RraB	NA|335aa|down_5|NZ_CP027457.1_1309399_1310404_+	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional	NA|591aa|down_6|NZ_CP027457.1_1310460_1312233_-	NA	NA|151aa|down_7|NZ_CP027457.1_1312355_1312808_-	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]	NA|198aa|down_8|NZ_CP027457.1_1312952_1313546_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|238aa|down_9|NZ_CP027457.1_1313616_1314330_+	PRK12742, PRK12742, SDR family oxidoreductase
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	5	2560693-2560794	4	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	TTGTTGATGTTGTTGTGTTTTGTA	24	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA|55aa|down_0|NZ_CP027457.1_2560834_2560999_-	NA|115aa|up_9|NZ_CP027457.1_2548365_2548710_-	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional	NA|313aa|up_8|NZ_CP027457.1_2548898_2549837_+	PRK10341, PRK10341, transcriptional regulator TdcA	NA|330aa|up_7|NZ_CP027457.1_2549935_2550925_+	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA|444aa|up_6|NZ_CP027457.1_2550946_2552278_+	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional	NA|403aa|up_5|NZ_CP027457.1_2552303_2553512_+	PRK12379, PRK12379, propionate kinase	NA|765aa|up_4|NZ_CP027457.1_2553545_2555840_+	cd01678, PFL1, Pyruvate formate lyase 1	NA|130aa|up_3|NZ_CP027457.1_2555853_2556243_+	PRK11401, PRK11401, enamine/imine deaminase	NA|455aa|up_2|NZ_CP027457.1_2556314_2557679_+	PRK15040, PRK15040, L-serine ammonia-lyase	NA|444aa|up_1|NZ_CP027457.1_2557953_2559285_+	TIGR00814, membrane_transport_protein_YhjV, serine transporter	NA|437aa|up_0|NZ_CP027457.1_2559312_2560623_+	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|55aa|down_0|NZ_CP027457.1_2560834_2560999_-	NA	NA|234aa|down_1|NZ_CP027457.1_2561021_2561723_-	COG1741, COG1741, Pirin-related protein [General function prediction only]	NA|299aa|down_2|NZ_CP027457.1_2561827_2562724_+	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold	NA|119aa|down_3|NZ_CP027457.1_2562774_2563131_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|122aa|down_4|NZ_CP027457.1_2563372_2563738_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|329aa|down_5|NZ_CP027457.1_2564020_2565007_-	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]	NA|161aa|down_6|NZ_CP027457.1_2565076_2565559_-	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|100aa|down_7|NZ_CP027457.1_2565654_2565954_-	pfam13997, YqjK, YqjK-like protein	NA|135aa|down_8|NZ_CP027457.1_2565943_2566348_-	COG5393, COG5393, Predicted membrane protein [Function unknown]	NA|102aa|down_9|NZ_CP027457.1_2566350_2566656_-	COG4575, ElaB, Uncharacterized conserved protein [Function unknown]
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	6	2946459-2947219	2,5,1	PILER-CR,CRISPRCasFinder,CRT	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	GAGTTCCCCGCGCCAGCGGGGATAAACCG,GAGTTCCCCGCGCCAGCGGGGATAAACCG,GAGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	1	1	2946915-2946946	NZ_CP027458.1_14337-14306	I-E:I-E:I-E	12,12,12	12	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|447aa|up_9|NZ_CP027457.1_2930754_2932095_+	TIGR03247, glucar-dehydr, glucarate dehydratase	NA|447aa|up_8|NZ_CP027457.1_2932115_2933456_+	TIGR03247, glucar-dehydr, glucarate dehydratase	NA|919aa|up_7|NZ_CP027457.1_2933688_2936445_-	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional	NA|434aa|up_6|NZ_CP027457.1_2936501_2937803_+	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	NA|745aa|up_5|NZ_CP027457.1_2937850_2940085_+	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|264aa|up_4|NZ_CP027457.1_2940180_2940972_+	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|546aa|up_3|NZ_CP027457.1_2941199_2942837_+	PRK05380, pyrG, CTP synthetase; Validated	NA|433aa|up_2|NZ_CP027457.1_2942924_2944223_+	PRK00077, eno, enolase; Provisional	NA|291aa|up_1|NZ_CP027457.1_2944282_2945155_-	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|224aa|up_0|NZ_CP027457.1_2945447_2946119_+	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|493aa|down_0|NZ_CP027457.1_2947856_2949335_-	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|426aa|down_1|NZ_CP027457.1_2949361_2950639_-	cd06174, MFS, Major Facilitator Superfamily	NA|262aa|down_2|NZ_CP027457.1_2950957_2951743_+	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|485aa|down_3|NZ_CP027457.1_2951812_2953267_+	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|446aa|down_4|NZ_CP027457.1_2953360_2954698_+	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|260aa|down_5|NZ_CP027457.1_2954675_2955455_+	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|287aa|down_6|NZ_CP027457.1_2955451_2956312_+	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|192aa|down_7|NZ_CP027457.1_2956459_2957035_-	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|87aa|down_8|NZ_CP027457.1_2957051_2957312_-	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|424aa|down_9|NZ_CP027457.1_2957302_2958574_-	PRK10015, PRK10015, oxidoreductase; Provisional
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	7	2966308-2966641	3,6,2	PILER-CR,CRISPRCasFinder,CRT	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	0	0	NA	NA	I-E:I-E:I-E	5,5,5	5	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|260aa|up_9|NZ_CP027457.1_2954675_2955455_+	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|287aa|up_8|NZ_CP027457.1_2955451_2956312_+	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|192aa|up_7|NZ_CP027457.1_2956459_2957035_-	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|87aa|up_6|NZ_CP027457.1_2957051_2957312_-	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|424aa|up_5|NZ_CP027457.1_2957302_2958574_-	PRK10015, PRK10015, oxidoreductase; Provisional	NA|122aa|up_4|NZ_CP027457.1_2958651_2959017_-	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS)	NA|600aa|up_3|NZ_CP027457.1_2959331_2961131_+	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit	NA|571aa|up_2|NZ_CP027457.1_2961130_2962843_+	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit	NA|245aa|up_1|NZ_CP027457.1_2962916_2963651_+	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|51aa|up_0|NZ_CP027457.1_2963915_2964068_+	pfam01848, HOK_GEF, Hok/gef family	NA|346aa|down_0|NZ_CP027457.1_2966722_2967760_-	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	NA|303aa|down_1|NZ_CP027457.1_2968011_2968920_+	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|476aa|down_2|NZ_CP027457.1_2968921_2970349_+	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|202aa|down_3|NZ_CP027457.1_2970348_2970954_+	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|108aa|down_4|NZ_CP027457.1_2971003_2971327_+	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|104aa|down_5|NZ_CP027457.1_2971520_2971832_+	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|237aa|down_6|NZ_CP027457.1_2971850_2972561_+	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|160aa|down_7|NZ_CP027457.1_2972560_2973040_+	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|350aa|down_8|NZ_CP027457.1_2973036_2974086_+	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|254aa|down_9|NZ_CP027457.1_2974066_2974828_+	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	8	3199923-3200044	7	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	GCGTCTTATCAGGCCTACAGTGAACAGAACC	31	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|271aa|up_9|NZ_CP027457.1_3190440_3191253_-	cd05348, BphB-like_SDR_c, cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs	NA|107aa|up_8|NZ_CP027457.1_3191249_3191570_-	PRK09965, PRK09965, 3-phenylpropionate dioxygenase ferredoxin subunit; Provisional	NA|173aa|up_7|NZ_CP027457.1_3191569_3192088_-	PRK10069, PRK10069, 3-phenylpropionate/cinnamic acid dioxygenase subunit beta	NA|454aa|up_6|NZ_CP027457.1_3192084_3193446_-	cd08881, RHO_alpha_C_NDO-like, C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases	NA|297aa|up_5|NZ_CP027457.1_3193581_3194472_+	PRK09906, PRK09906, DNA-binding transcriptional regulator HcaR; Provisional	NA|380aa|up_4|NZ_CP027457.1_3194631_3195771_+	PRK11128, PRK11128, 3-phenylpropionate MFS transporter	NA|427aa|up_3|NZ_CP027457.1_3195762_3197043_-	PRK11564, PRK11564, stationary phase inducible protein CsiE; Provisional	NA|285aa|up_2|NZ_CP027457.1_3197233_3198088_-	COG1073, COG1073, Hydrolases of the alpha/beta superfamily [General function prediction only]	NA|268aa|up_1|NZ_CP027457.1_3198232_3199036_-	PRK10757, PRK10757, inositol-1-monophosphatase	NA|247aa|up_0|NZ_CP027457.1_3199154_3199895_+	PRK15114, PRK15114, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional	NA|163aa|down_0|NZ_CP027457.1_3200255_3200744_+	PRK10857, PRK10857, Fe-S cluster assembly transcriptional regulator IscR	NA|405aa|down_1|NZ_CP027457.1_3200855_3202070_+	PRK14012, PRK14012, IscS subfamily cysteine desulfurase	NA|129aa|down_2|NZ_CP027457.1_3202097_3202484_+	PRK11325, PRK11325, scaffold protein; Provisional	NA|108aa|down_3|NZ_CP027457.1_3202500_3202824_+	PRK09502, iscA, iron-sulfur cluster assembly protein IscA	NA|172aa|down_4|NZ_CP027457.1_3202919_3203435_+	PRK05014, hscB, co-chaperone HscB; Provisional	NA|617aa|down_5|NZ_CP027457.1_3203451_3205302_+	PRK05183, hscA, chaperone protein HscA; Provisional	NA|112aa|down_6|NZ_CP027457.1_3205303_3205639_+	TIGR02007, 2Fe-2S_ferredoxin, ferredoxin, 2Fe-2S type, ISC system	NA|67aa|down_7|NZ_CP027457.1_3205650_3205851_+	PRK10721, PRK10721, hypothetical protein; Provisional	NA|428aa|down_8|NZ_CP027457.1_3206028_3207312_+	PRK05015, PRK05015, aminopeptidase B; Provisional	NA|259aa|down_9|NZ_CP027457.1_3207453_3208230_+	PRK11611, PRK11611, enhanced serine sensitivity protein SseB; Provisional
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	9	3294204-3294355	8	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	CGCATCCGCCAGTGGCGCGGTGCAATTGCCGGATGCGATGCTTGCCGCGTCT	52	1	1	3294256-3294303	NZ_CP027457.1_2583579-2583626	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|112aa|up_9|NZ_CP027457.1_3286646_3286982_+	PRK15468, PRK15468, ethanolamine utilization microcompartment protein EutS	NA|160aa|up_8|NZ_CP027457.1_3286994_3287474_+	PRK15467, PRK15467, ethanolamine utilization acetate kinase EutP	NA|234aa|up_7|NZ_CP027457.1_3287448_3288150_+	PRK15457, PRK15457, ethanolamine utilization acetate kinase EutQ	NA|268aa|up_6|NZ_CP027457.1_3288146_3288950_+	PRK15020, PRK15020, ethanolamine utilization cob(I)yrinic acid a,c-diamide adenosyltransferase EutT	NA|339aa|up_5|NZ_CP027457.1_3288946_3289963_+	PRK09653, eutD, phosphotransacetylase	NA|98aa|up_4|NZ_CP027457.1_3290001_3290295_+	PRK15474, PRK15474, ethanolamine utilization microcompartment protein EutM	NA|96aa|up_3|NZ_CP027457.1_3290401_3290689_+	PRK15448, PRK15448, ethanolamine utilization microcompartment protein EutN	NA|468aa|up_2|NZ_CP027457.1_3290700_3292104_+	PRK15398, PRK15398, aldehyde dehydrogenase	NA|279aa|up_1|NZ_CP027457.1_3292114_3292951_+	COG4820, EutJ, Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]	NA|396aa|up_0|NZ_CP027457.1_3292940_3294128_+	PRK15454, PRK15454, ethanolamine utilization ethanol dehydrogenase EutG	NA|409aa|down_0|NZ_CP027457.1_3294444_3295671_+	COG3192, EutH, Ethanolamine utilization protein [Amino acid transport and metabolism]	NA|468aa|down_1|NZ_CP027457.1_3295667_3297071_+	PRK10719, eutA, ethanolamine ammonia-lyase reactivating factor EutA	NA|454aa|down_2|NZ_CP027457.1_3297082_3298444_+	COG4303, EutB, Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]	NA|296aa|down_3|NZ_CP027457.1_3298464_3299352_+	COG4302, EutC, Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]	NA|220aa|down_4|NZ_CP027457.1_3299361_3300021_+	PRK15405, PRK15405, ethanolamine utilization microcompartment protein EutL	NA|167aa|down_5|NZ_CP027457.1_3300033_3300534_+	PRK15466, PRK15466, ethanolamine utilization microcompartment protein EutK	NA|351aa|down_6|NZ_CP027457.1_3300579_3301632_+	PRK10130, PRK10130, HTH-type transcriptional regulator EutR	NA|300aa|down_7|NZ_CP027457.1_3301637_3302537_-	PRK05330, PRK05330, oxygen-dependent coproporphyrinogen oxidase	NA|290aa|down_8|NZ_CP027457.1_3302540_3303410_-	PRK10319, PRK10319, N-acetylmuramoyl-L-alanine amidase AmiA	NA|142aa|down_9|NZ_CP027457.1_3303623_3304049_+	PRK03624, PRK03624, putative acetyltransferase; Provisional
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	10	3417090-3417233	9	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	CTACGCAGGGGTAGAACCGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACA	53	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|407aa|up_9|NZ_CP027457.1_3406480_3407701_+	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I	NA|393aa|up_8|NZ_CP027457.1_3407984_3409163_+	PRK12382, PRK12382, putative transporter; Provisional	NA|332aa|up_7|NZ_CP027457.1_3409159_3410155_-	PRK10715, flk, flagella biosynthesis regulator Flk	NA|379aa|up_6|NZ_CP027457.1_3410253_3411390_+	PRK15438, PRK15438, erythronate-4-phosphate dehydrogenase PdxB; Provisional	NA|338aa|up_5|NZ_CP027457.1_3411455_3412469_+	PRK08040, PRK08040, putative semialdehyde dehydrogenase; Provisional	NA|271aa|up_4|NZ_CP027457.1_3412468_3413281_+	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA	NA|220aa|up_3|NZ_CP027457.1_3413363_3414023_+	PRK10847, PRK10847, DedA family protein	NA|305aa|up_2|NZ_CP027457.1_3414178_3415093_+	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta	NA|423aa|up_1|NZ_CP027457.1_3415162_3416431_+	PRK10846, PRK10846, bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional	NA|221aa|up_0|NZ_CP027457.1_3416420_3417083_+	PRK11633, PRK11633, cell division protein DedD; Provisional	NA|163aa|down_0|NZ_CP027457.1_3417397_3417886_+	PRK10845, PRK10845, colicin V production protein; Provisional	NA|506aa|down_1|NZ_CP027457.1_3417922_3419440_+	PRK09246, PRK09246, amidophosphoribosyltransferase; Provisional	NA|190aa|down_2|NZ_CP027457.1_3419534_3420104_+	PRK06029, PRK06029, UbiX family flavin prenyltransferase	NA|261aa|down_3|NZ_CP027457.1_3420369_3421152_+	PRK15010, PRK15010, lysine/arginine/ornithine ABC transporter substrate-binding protein ArgT	NA|261aa|down_4|NZ_CP027457.1_3421372_3422155_+	PRK15437, PRK15437, histidine ABC transporter substrate-binding protein HisJ; Provisional	NA|229aa|down_5|NZ_CP027457.1_3422244_3422931_+	PRK15135, PRK15135, histidine ABC transporter permease HisQ	NA|239aa|down_6|NZ_CP027457.1_3422927_3423644_+	PRK15069, PRK15069, histidine ABC transporter permease HisM	NA|258aa|down_7|NZ_CP027457.1_3423651_3424425_+	PRK10619, PRK10619, histidine ABC transporter ATP-binding protein HisP	NA|297aa|down_8|NZ_CP027457.1_3424621_3425512_+	PRK09857, PRK09857, recombination-promoting nuclease RpnA	NA|298aa|down_9|NZ_CP027457.1_3425559_3426453_-	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	11	3498217-3498356	10	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	GCCTGATGCGACGCTGGCGCGTCTAATCAGGCCTACAAACCGAGCCGTAGGCC	53	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA,NA	NA|397aa|up_9|NZ_CP027457.1_3486933_3488124_-	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	NA|420aa|up_8|NZ_CP027457.1_3488120_3489380_-	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]	NA|543aa|up_7|NZ_CP027457.1_3489369_3490998_-	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA|453aa|up_6|NZ_CP027457.1_3491270_3492629_+	PRK11273, glpT, glycerol-3-phosphate transporter	NA|360aa|up_5|NZ_CP027457.1_3492633_3493713_+	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional	NA|293aa|up_4|NZ_CP027457.1_3493757_3494636_-	COG0583, LysR, Transcriptional regulator [Transcription]	NA|397aa|up_3|NZ_CP027457.1_3494800_3495991_+	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily	NA|217aa|up_2|NZ_CP027457.1_3496071_3496722_+	PRK09902, PRK09902, lipopolysaccharide kinase InaA	NA|85aa|up_1|NZ_CP027457.1_3496775_3497030_-	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein	NA|377aa|up_0|NZ_CP027457.1_3497029_3498160_-	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed	NA|762aa|down_0|NZ_CP027457.1_3498392_3500678_-	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha	NA|1251aa|down_1|NZ_CP027457.1_3501373_3505126_+	PRK09752, PRK09752, AIDA-I family autotransporter YfaL	NA|241aa|down_2|NZ_CP027457.1_3505266_3505989_-	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	NA|876aa|down_3|NZ_CP027457.1_3506135_3508763_+	PRK05560, PRK05560, DNA gyrase subunit A; Validated	NA|563aa|down_4|NZ_CP027457.1_3508911_3510600_+	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown]	NA|208aa|down_5|NZ_CP027457.1_3510596_3511220_+	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown]	NA|1465aa|down_6|NZ_CP027457.1_3511363_3515758_+	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only]	NA|550aa|down_7|NZ_CP027457.1_3515758_3517408_+	COG5445, COG5445, Predicted secreted protein [Function unknown]	NA|259aa|down_8|NZ_CP027457.1_3517412_3518189_+	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown]	NA|950aa|down_9|NZ_CP027457.1_3518463_3521313_+	PRK10841, PRK10841, two-component system sensor histidine kinase RcsC
GCF_003018115.1_ASM301811v1	NZ_CP027457	Escherichia coli strain 88-3493 chromosome, complete genome	12	4974116-4974207	11	CRISPRCasFinder	no		DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	Orphan	CCACCTTTTTTACCTGCTTCAGATGC	26	0	0	NA	NA	NA	1	1	Orphan	DinG,DEDDh,c2c9_V-U4,cas3,csa3,cas14j	NA|70aa|up_8|NZ_CP027457.1_4963255_4963465_-,NA	NA|503aa|up_9|NZ_CP027457.1_4961588_4963097_-	PRK15419, PRK15419, sodium/proline symporter PutP	NA|70aa|up_8|NZ_CP027457.1_4963255_4963465_-	NA	NA|1321aa|up_7|NZ_CP027457.1_4963519_4967482_+	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed	NA|213aa|up_6|NZ_CP027457.1_4967521_4968160_-	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional	NA|364aa|up_5|NZ_CP027457.1_4968447_4969539_+	TIGR03612, RutA, pyrimidine utilization protein A	NA|231aa|up_4|NZ_CP027457.1_4969538_4970231_+	TIGR03614, RutB, pyrimidine utilization protein B	NA|129aa|up_3|NZ_CP027457.1_4970242_4970629_+	TIGR03610, RutC, pyrimidine utilization protein C	NA|197aa|up_2|NZ_CP027457.1_4971382_4971973_+	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|165aa|up_1|NZ_CP027457.1_4971983_4972478_+	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F	NA|443aa|up_0|NZ_CP027457.1_4972498_4973827_+	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|199aa|down_0|NZ_CP027457.1_4974630_4975227_+	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|76aa|down_1|NZ_CP027457.1_4975247_4975475_+	PRK10174, PRK10174, hypothetical protein; Provisional	NA|414aa|down_2|NZ_CP027457.1_4975512_4976754_-	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional	NA|417aa|down_3|NZ_CP027457.1_4977046_4978297_-	PRK09784, PRK09784, YccE family protein	NA|307aa|down_4|NZ_CP027457.1_4978556_4979477_+	PRK10266, PRK10266, curved DNA-binding protein	NA|102aa|down_5|NZ_CP027457.1_4979476_4979782_+	PRK10265, PRK10265, chaperone modulator CbpM	NA|200aa|down_6|NZ_CP027457.1_4979933_4980533_-	PRK04976, torD, chaperone protein TorD; Validated	NA|849aa|down_7|NZ_CP027457.1_4980529_4983076_-	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA	NA|391aa|down_8|NZ_CP027457.1_4983075_4984248_-	PRK15032, PRK15032, pentaheme c-type cytochrome TorC	NA|231aa|down_9|NZ_CP027457.1_4984377_4985070_+	PRK10766, PRK10766, two-component system response regulator TorR
