assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	1	366443-367141	1	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366731-366772|366806-366838	NZ_CP025608.1_374762-374803|NZ_CP025608.1_373577-373609	NA	10	10	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|101aa|up_4|NZ_CP025608.1_363455_363758_+,NA|161aa|down_1|NZ_CP025608.1_376551_377034_-,NA|410aa|down_5|NZ_CP025608.1_379150_380380_+	NA|262aa|up_9|NZ_CP025608.1_358150_358936_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP025608.1_358924_359728_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP025608.1_359737_361135_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP025608.1_361313_363089_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP025608.1_363231_363459_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP025608.1_363455_363758_+	NA	NA|74aa|up_3|NZ_CP025608.1_363805_364027_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP025608.1_364023_364449_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP025608.1_364584_365217_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP025608.1_365213_366122_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP025608.1_375892_376564_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP025608.1_376551_377034_-	NA	NA|239aa|down_2|NZ_CP025608.1_377091_377808_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP025608.1_377909_378566_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP025608.1_378635_379127_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP025608.1_379150_380380_+	NA	NA|621aa|down_6|NZ_CP025608.1_380534_382397_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP025608.1_382468_382855_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP025608.1_382857_383520_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP025608.1_383580_384465_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	2	631237-631374	1	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	CCGCCGACCACGCCGGTG	18	2	3	631255-631272|631255-631272|631339-631356	NZ_CP025608.1_22466-22483|NZ_CP025608.1_1412036-1412053|NZ_CP025608.1_973204-973221	NA	3	3	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|54aa|up_7|NZ_CP025608.1_622075_622237_-,NA|478aa|up_0|NZ_CP025608.1_628252_629686_-,NA|450aa|down_2|NZ_CP025608.1_633009_634359_-,NA|93aa|down_5|NZ_CP025608.1_635889_636168_-	NA|325aa|up_9|NZ_CP025608.1_619845_620820_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP025608.1_620861_622079_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP025608.1_622075_622237_-	NA	NA|106aa|up_6|NZ_CP025608.1_622283_622601_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|595aa|up_5|NZ_CP025608.1_622747_624532_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP025608.1_624427_625435_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP025608.1_625516_626395_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP025608.1_626411_627206_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP025608.1_627202_628243_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP025608.1_628252_629686_-	NA	NA|211aa|down_0|NZ_CP025608.1_631697_632330_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP025608.1_632326_632989_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP025608.1_633009_634359_-	NA	NA|381aa|down_3|NZ_CP025608.1_634370_635513_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP025608.1_635527_635830_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP025608.1_635889_636168_-	NA	NA|418aa|down_6|NZ_CP025608.1_636164_637418_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP025608.1_637537_637924_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP025608.1_637986_638871_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP025608.1_638966_639869_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	3	691980-692056	2	CRISPRCasFinder	no	c2c9_V-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA,NA	NA|72aa|up_9|NZ_CP025608.1_677664_677880_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP025608.1_677876_678284_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP025608.1_678343_679030_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP025608.1_679183_681817_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP025608.1_681839_684227_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP025608.1_684364_685087_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP025608.1_685083_685881_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP025608.1_685882_686770_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP025608.1_686775_687990_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP025608.1_689013_690459_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP025608.1_693191_694742_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP025608.1_694793_695186_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP025608.1_695182_695440_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP025608.1_695622_696858_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP025608.1_697108_697522_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP025608.1_697518_697755_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP025608.1_697858_698365_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP025608.1_698478_698949_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP025608.1_698992_699754_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP025608.1_699810_700122_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	4	926575-927522	2	CRT	no	csa3	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927358-927393|927358-927393|927358-927393	NZ_CP025608.1_675083-675048|NZ_CP025608.1_1213719-1213754|NZ_CP025608.1_2423759-2423724	NA	19	19	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA,NA|184aa|down_2|NZ_CP025608.1_931523_932075_-,NA|81aa|down_8|NZ_CP025608.1_937538_937781_+	NA|626aa|up_9|NZ_CP025608.1_914388_916266_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP025608.1_916431_917601_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP025608.1_917688_918705_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP025608.1_918866_919508_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP025608.1_919588_920644_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP025608.1_920695_921088_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP025608.1_921145_921568_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP025608.1_921529_921820_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP025608.1_921924_922830_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP025608.1_922848_923664_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|880aa|down_0|NZ_CP025608.1_927791_930431_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP025608.1_930898_931543_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP025608.1_931523_932075_-	NA	NA|218aa|down_3|NZ_CP025608.1_932224_932878_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP025608.1_932948_933977_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP025608.1_934665_935436_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP025608.1_935522_936335_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP025608.1_936402_937263_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP025608.1_937538_937781_+	NA	NA|431aa|down_9|NZ_CP025608.1_938057_939350_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	5	1191286-1191394	3	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA,NA	NA|544aa|up_9|NZ_CP025608.1_1180653_1182285_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP025608.1_1182360_1183425_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP025608.1_1183477_1183951_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP025608.1_1183984_1184848_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP025608.1_1184852_1185710_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP025608.1_1185710_1186793_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP025608.1_1186873_1187293_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP025608.1_1187404_1187971_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP025608.1_1187967_1188363_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP025608.1_1188390_1190394_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP025608.1_1192479_1194243_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP025608.1_1194239_1195013_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP025608.1_1195024_1196062_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP025608.1_1196248_1197085_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP025608.1_1197200_1198052_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP025608.1_1198125_1199343_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP025608.1_1199395_1200340_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP025608.1_1200562_1201630_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP025608.1_1201686_1203081_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP025608.1_1203282_1204005_+	pfam06271, RDD, RDD family
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	6	1211920-1212776	4	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	73	1212303-1212324|1212348-1212363|1212486-1212507|1212486-1212507|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621|1212603-1212621	NZ_CP025608.1_2960536-2960515|NZ_CP025608.1_2088569-2088554|NZ_CP025608.1_837389-837410|NZ_CP025608.1_1217614-1217635|NZ_CP025608.1_674747-674729|NZ_CP025608.1_1213446-1213464|NZ_CP025608.1_1217587-1217605|NZ_CP025608.1_1217659-1217677|NZ_CP025608.1_1630669-1630651|NZ_CP025608.1_1990774-1990756|NZ_CP025608.1_2061497-2061479|NZ_CP025608.1_2061944-2061926|NZ_CP025608.1_2062043-2062025|NZ_CP025608.1_2802095-2802077|NZ_CP025608.1_2805623-2805605|NZ_CP025608.1_150180-150198|NZ_CP025608.1_333781-333763|NZ_CP025608.1_335200-335182|NZ_CP025608.1_335653-335635|NZ_CP025608.1_335704-335686|NZ_CP025608.1_335713-335695|NZ_CP025608.1_337983-337965|NZ_CP025608.1_338112-338094|NZ_CP025608.1_338379-338361|NZ_CP025608.1_338408-338426|NZ_CP025608.1_338502-338484|NZ_CP025608.1_363033-363015|NZ_CP025608.1_443405-443387|NZ_CP025608.1_546748-546730|NZ_CP025608.1_623938-623956|NZ_CP025608.1_624160-624178|NZ_CP025608.1_673913-673895|NZ_CP025608.1_840172-840190|NZ_CP025608.1_1090945-1090963|NZ_CP025608.1_1091593-1091611|NZ_CP025608.1_1212975-1212993|NZ_CP025608.1_1213365-1213383|NZ_CP025608.1_1218007-1218025|NZ_CP025608.1_1489180-1489162|NZ_CP025608.1_1618633-1618615|NZ_CP025608.1_1619086-1619068|NZ_CP025608.1_1635999-1635981|NZ_CP025608.1_1636008-1635990|NZ_CP025608.1_1864288-1864270|NZ_CP025608.1_1864816-1864798|NZ_CP025608.1_1990048-1990030|NZ_CP025608.1_2001410-2001428|NZ_CP025608.1_2088767-2088749|NZ_CP025608.1_2303481-2303463|NZ_CP025608.1_2356935-2356917|NZ_CP025608.1_2419585-2419603|NZ_CP025608.1_2423672-2423654|NZ_CP025608.1_2569167-2569149|NZ_CP025608.1_2693465-2693483|NZ_CP025608.1_2795409-2795391|NZ_CP025608.1_2795991-2795973|NZ_CP025608.1_3054575-3054593|NZ_CP025608.1_3054674-3054692|NZ_CP025608.1_3705515-3705533|NZ_CP025608.1_3737492-3737474|NZ_CP025608.1_3738116-3738098|NZ_CP025608.1_3738359-3738341|NZ_CP025608.1_3738492-3738474|NZ_CP025608.1_3802361-3802379|NZ_CP025608.1_3802544-3802562|NZ_CP025608.1_3802712-3802730|NZ_CP025608.1_3930525-3930543|NZ_CP025608.1_3932255-3932273|NZ_CP025608.1_3934865-3934883|NZ_CP025608.1_3940744-3940762|NZ_CP025608.1_3944536-3944554|NZ_CP025608.1_4031721-4031703|NZ_CP025608.1_4094246-4094264	NA	16	16	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|89aa|up_3|NZ_CP025608.1_1207352_1207619_+,NA|61aa|down_3|NZ_CP025608.1_1215194_1215377_+,NA|35aa|down_4|NZ_CP025608.1_1215486_1215591_+	NA|465aa|up_9|NZ_CP025608.1_1201686_1203081_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP025608.1_1203282_1204005_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP025608.1_1204036_1205203_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP025608.1_1205273_1205768_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP025608.1_1205953_1206388_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP025608.1_1206489_1207356_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP025608.1_1207352_1207619_+	NA	NA|674aa|up_2|NZ_CP025608.1_1207605_1209627_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP025608.1_1209725_1210454_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP025608.1_1210564_1211353_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP025608.1_1214009_1214330_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP025608.1_1214482_1214917_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP025608.1_1215015_1215183_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP025608.1_1215194_1215377_+	NA	NA|35aa|down_4|NZ_CP025608.1_1215486_1215591_+	NA	NA|152aa|down_5|NZ_CP025608.1_1215568_1216024_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP025608.1_1216438_1219000_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP025608.1_1219217_1220156_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP025608.1_1220543_1221824_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP025608.1_1221928_1222756_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	7	1572156-1573228	5	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|106aa|up_7|NZ_CP025608.1_1563919_1564237_+,NA	NA|103aa|up_9|NZ_CP025608.1_1561434_1561743_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP025608.1_1561739_1563359_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP025608.1_1563919_1564237_+	NA	NA|209aa|up_6|NZ_CP025608.1_1564371_1564998_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP025608.1_1565063_1565396_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP025608.1_1565411_1566668_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP025608.1_1566795_1568007_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP025608.1_1568079_1569558_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP025608.1_1569554_1570940_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP025608.1_1571017_1572052_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP025608.1_1574082_1574484_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP025608.1_1574480_1574738_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP025608.1_1574820_1575780_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP025608.1_1575804_1576767_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP025608.1_1576900_1577503_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP025608.1_1577583_1579551_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP025608.1_1579568_1580393_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP025608.1_1580561_1581044_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP025608.1_1581115_1581940_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP025608.1_1582136_1583075_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	8	2088239-2088493	3	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088320-2088337|2088320-2088337|2088410-2088427	NZ_CP025608.1_401057-401040|NZ_CP025608.1_607393-607376|NZ_CP025608.1_3450203-3450186	NA	5	5	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|88aa|up_0|NZ_CP025608.1_2087598_2087862_-,NA	NA|165aa|up_9|NZ_CP025608.1_2073892_2074387_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP025608.1_2074790_2075468_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP025608.1_2075826_2078652_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP025608.1_2078878_2079739_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP025608.1_2079779_2080646_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP025608.1_2080650_2082537_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP025608.1_2082552_2084586_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP025608.1_2084705_2086931_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP025608.1_2087206_2087602_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP025608.1_2087598_2087862_-	NA	NA|346aa|down_0|NZ_CP025608.1_2089630_2090668_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP025608.1_2090667_2092035_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP025608.1_2092208_2093645_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP025608.1_2093680_2095132_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP025608.1_2095161_2096112_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP025608.1_2096126_2096543_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP025608.1_2096820_2097243_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP025608.1_2097291_2097594_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP025608.1_2097590_2097905_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP025608.1_2097904_2099638_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	9	2163345-2163452	6	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGTGAC	39	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|136aa|up_2|NZ_CP025608.1_2159889_2160297_-,NA|127aa|down_6|NZ_CP025608.1_2176518_2176899_-	NA|216aa|up_9|NZ_CP025608.1_2153203_2153851_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP025608.1_2153857_2156080_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP025608.1_2156117_2156561_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP025608.1_2156674_2157268_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP025608.1_2157350_2157956_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP025608.1_2158055_2159060_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP025608.1_2159159_2159912_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP025608.1_2159889_2160297_-	NA	NA|368aa|up_1|NZ_CP025608.1_2160431_2161535_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP025608.1_2161534_2162731_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP025608.1_2167617_2170581_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP025608.1_2171029_2171494_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP025608.1_2171591_2172455_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP025608.1_2172492_2173764_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP025608.1_2174035_2175151_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP025608.1_2175141_2176482_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP025608.1_2176518_2176899_-	NA	NA|621aa|down_7|NZ_CP025608.1_2177055_2178918_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP025608.1_2178925_2179405_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP025608.1_2179641_2180415_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	10	2168783-2169002	7	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|136aa|up_3|NZ_CP025608.1_2159889_2160297_-,NA|127aa|down_5|NZ_CP025608.1_2176518_2176899_-	NA|741aa|up_9|NZ_CP025608.1_2153857_2156080_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP025608.1_2156117_2156561_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP025608.1_2156674_2157268_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP025608.1_2157350_2157956_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP025608.1_2158055_2159060_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP025608.1_2159159_2159912_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP025608.1_2159889_2160297_-	NA	NA|368aa|up_2|NZ_CP025608.1_2160431_2161535_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP025608.1_2161534_2162731_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP025608.1_2162900_2167280_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP025608.1_2171029_2171494_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP025608.1_2171591_2172455_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP025608.1_2172492_2173764_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP025608.1_2174035_2175151_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP025608.1_2175141_2176482_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP025608.1_2176518_2176899_-	NA	NA|621aa|down_6|NZ_CP025608.1_2177055_2178918_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP025608.1_2178925_2179405_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP025608.1_2179641_2180415_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP025608.1_2180418_2181186_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	11	3119166-3120519	1,8,4	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	16,17,18	18	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|85aa|up_8|NZ_CP025608.1_3112445_3112700_-,NA|135aa|up_7|NZ_CP025608.1_3112847_3113252_+,NA|64aa|up_6|NZ_CP025608.1_3113248_3113440_+,NA|86aa|up_4|NZ_CP025608.1_3115026_3115284_+,NA|104aa|up_3|NZ_CP025608.1_3115388_3115700_+,NA|203aa|up_2|NZ_CP025608.1_3116119_3116728_+,NA	NA|92aa|up_9|NZ_CP025608.1_3111994_3112270_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP025608.1_3112445_3112700_-	NA	NA|135aa|up_7|NZ_CP025608.1_3112847_3113252_+	NA	NA|64aa|up_6|NZ_CP025608.1_3113248_3113440_+	NA	NA|385aa|up_5|NZ_CP025608.1_3113638_3114793_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP025608.1_3115026_3115284_+	NA	NA|104aa|up_3|NZ_CP025608.1_3115388_3115700_+	NA	NA|203aa|up_2|NZ_CP025608.1_3116119_3116728_+	NA	NA|470aa|up_1|NZ_CP025608.1_3116798_3118208_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP025608.1_3118204_3119017_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP025608.1_3120545_3121807_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP025608.1_3123609_3123951_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP025608.1_3123951_3124968_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP025608.1_3124980_3126129_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP025608.1_3126224_3127352_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP025608.1_3127348_3128257_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP025608.1_3128237_3128948_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP025608.1_3128957_3129332_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|816aa|down_8|NZ_CP025608.1_3129328_3131776_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	NA|182aa|down_9|NZ_CP025608.1_3132893_3133439_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	12	3121842-3123561	9,5,2	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|85aa|up_9|NZ_CP025608.1_3112445_3112700_-,NA|135aa|up_8|NZ_CP025608.1_3112847_3113252_+,NA|64aa|up_7|NZ_CP025608.1_3113248_3113440_+,NA|86aa|up_5|NZ_CP025608.1_3115026_3115284_+,NA|104aa|up_4|NZ_CP025608.1_3115388_3115700_+,NA|203aa|up_3|NZ_CP025608.1_3116119_3116728_+,NA	NA|85aa|up_9|NZ_CP025608.1_3112445_3112700_-	NA	NA|135aa|up_8|NZ_CP025608.1_3112847_3113252_+	NA	NA|64aa|up_7|NZ_CP025608.1_3113248_3113440_+	NA	NA|385aa|up_6|NZ_CP025608.1_3113638_3114793_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP025608.1_3115026_3115284_+	NA	NA|104aa|up_4|NZ_CP025608.1_3115388_3115700_+	NA	NA|203aa|up_3|NZ_CP025608.1_3116119_3116728_+	NA	NA|470aa|up_2|NZ_CP025608.1_3116798_3118208_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP025608.1_3118204_3119017_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP025608.1_3120545_3121807_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP025608.1_3123609_3123951_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP025608.1_3123951_3124968_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP025608.1_3124980_3126129_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP025608.1_3126224_3127352_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP025608.1_3127348_3128257_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP025608.1_3128237_3128948_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP025608.1_3128957_3129332_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|816aa|down_7|NZ_CP025608.1_3129328_3131776_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	NA|182aa|down_8|NZ_CP025608.1_3132893_3133439_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|295aa|down_9|NZ_CP025608.1_3133710_3134595_-	COG2253, COG2253, Uncharacterized conserved protein [Function unknown]
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	13	3740686-3741446	6	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	CCGCCGNTNCCNCCGTNNCCGCC	23	0	0	NA	NA	NA	10	10	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA,NA|96aa|down_4|NZ_CP025608.1_3755328_3755616_-,NA|87aa|down_9|NZ_CP025608.1_3768736_3768997_-	NA|147aa|up_9|NZ_CP025608.1_3721257_3721698_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_8|NZ_CP025608.1_3721731_3722601_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_7|NZ_CP025608.1_3722621_3723632_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_6|NZ_CP025608.1_3723916_3724549_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_5|NZ_CP025608.1_3724615_3725845_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_4|NZ_CP025608.1_3726127_3727477_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_CP025608.1_3727488_3728628_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_CP025608.1_3728624_3729356_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_1|NZ_CP025608.1_3729364_3736936_-	pfam00823, PPE, PPE family	NA|339aa|up_0|NZ_CP025608.1_3736984_3738001_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|86aa|down_0|NZ_CP025608.1_3743198_3743456_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP025608.1_3743711_3753185_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP025608.1_3753810_3754257_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP025608.1_3754293_3755034_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP025608.1_3755328_3755616_-	NA	NA|3717aa|down_5|NZ_CP025608.1_3755952_3767103_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP025608.1_3767346_3768141_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP025608.1_3768222_3768594_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP025608.1_3768491_3768710_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP025608.1_3768736_3768997_-	NA
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	14	3948351-3949349	7	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	CNNCGGCGGCACCGGCGGCNNNGGCGGCNCCGGCGG	36	9	13	3948477-3948524|3948561-3948596|3948774-3948827|3948864-3948905|3948942-3948977|3948942-3948977|3948942-3948977|3948942-3948977|3948942-3948977|3949014-3949049|3949086-3949133|3949170-3949205|3949242-3949313	NZ_CP025608.1_3949677-3949724|NZ_CP025608.1_3949761-3949796|NZ_CP025608.1_3949377-3949430|NZ_CP025608.1_3949467-3949508|NZ_CP025608.1_3947058-3947093|NZ_CP025608.1_3947400-3947435|NZ_CP025608.1_3947991-3948026|NZ_CP025608.1_3948342-3948377|NZ_CP025608.1_3932810-3932845|NZ_CP025608.1_3949614-3949649|NZ_CP025608.1_3949686-3949733|NZ_CP025608.1_3949770-3949805|NZ_CP025608.1_3949842-3949913	NA	12	12	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA,NA|280aa|down_2|NZ_CP025608.1_3953417_3954257_+	NA|64aa|up_9|NZ_CP025608.1_3922070_3922262_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_8|NZ_CP025608.1_3922476_3923679_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_7|NZ_CP025608.1_3923703_3924825_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_6|NZ_CP025608.1_3924895_3926404_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1382aa|up_5|NZ_CP025608.1_3926574_3930720_+	pfam00934, PE, PE family	NA|1896aa|up_4|NZ_CP025608.1_3931010_3936698_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP025608.1_3936864_3938412_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP025608.1_3938408_3939245_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1782aa|up_1|NZ_CP025608.1_3939604_3944950_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP025608.1_3945078_3945735_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP025608.1_3950810_3952457_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP025608.1_3952530_3953322_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP025608.1_3953417_3954257_+	NA	NA|399aa|down_3|NZ_CP025608.1_3954311_3955508_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP025608.1_3955536_3956247_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP025608.1_3956311_3957355_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP025608.1_3957507_3958419_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP025608.1_3958434_3959499_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP025608.1_3959515_3960700_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP025608.1_3960741_3961773_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002886585.1_ASM288658v1	NZ_CP025608	Mycobacterium tuberculosis strain GG-229-10 chromosome, complete genome	15	4110663-4110751	10	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	NA|257aa|up_8|NZ_CP025608.1_4101249_4102020_-,NA|119aa|up_3|NZ_CP025608.1_4107154_4107511_+,NA|52aa|up_2|NZ_CP025608.1_4107610_4107766_+,NA|233aa|up_0|NZ_CP025608.1_4109767_4110466_-,NA|126aa|down_6|NZ_CP025608.1_4115986_4116364_+	NA|288aa|up_9|NZ_CP025608.1_4099631_4100495_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP025608.1_4101249_4102020_-	NA	NA|549aa|up_7|NZ_CP025608.1_4102016_4103663_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP025608.1_4103659_4104523_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP025608.1_4104515_4105442_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP025608.1_4105443_4107069_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP025608.1_4107154_4107511_+	NA	NA|52aa|up_2|NZ_CP025608.1_4107610_4107766_+	NA	NA|652aa|up_1|NZ_CP025608.1_4107776_4109732_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP025608.1_4109767_4110466_-	NA	NA|173aa|down_0|NZ_CP025608.1_4110811_4111330_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP025608.1_4111330_4112314_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP025608.1_4112306_4113500_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP025608.1_4113505_4114327_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP025608.1_4114458_4115142_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP025608.1_4115141_4115879_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP025608.1_4115986_4116364_+	NA	NA|225aa|down_7|NZ_CP025608.1_4116462_4117137_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP025608.1_4117242_4118037_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP025608.1_4118043_4118499_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
