assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	1	338106-338328	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_CP023634.1_333161_333344_-,NA	NA|561aa|up_9|NZ_CP023634.1_324568_326251_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP023634.1_326267_328463_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP023634.1_328576_329710_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP023634.1_329706_330327_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP023634.1_330423_331005_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP023634.1_330934_331660_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP023634.1_331749_332670_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP023634.1_332709_333138_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP023634.1_333161_333344_-	NA	NA|958aa|up_0|NZ_CP023634.1_333438_336312_-	pfam00934, PE, PE family	NA|537aa|down_0|NZ_CP023634.1_339365_340976_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP023634.1_340999_341908_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP023634.1_342131_344027_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP023634.1_344023_345640_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP023634.1_345636_349629_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP023634.1_349625_349934_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP023634.1_349936_351478_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP023634.1_351526_351820_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP023634.1_351849_352140_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP023634.1_352150_353038_+	pfam14011, ESX-1_EspG, EspG family
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	2	366465-367163	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366753-366794|366828-366860	NZ_CP023634.1_374784-374825|NZ_CP023634.1_373599-373631	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023634.1_363477_363780_+,NA|161aa|down_1|NZ_CP023634.1_376573_377056_-,NA|410aa|down_5|NZ_CP023634.1_379172_380402_+	NA|262aa|up_9|NZ_CP023634.1_358172_358958_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023634.1_358946_359750_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023634.1_359759_361157_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023634.1_361335_363111_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023634.1_363253_363481_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023634.1_363477_363780_+	NA	NA|74aa|up_3|NZ_CP023634.1_363827_364049_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023634.1_364045_364471_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023634.1_364606_365239_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023634.1_365235_366144_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023634.1_375914_376586_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023634.1_376573_377056_-	NA	NA|239aa|down_2|NZ_CP023634.1_377113_377830_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023634.1_377931_378588_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023634.1_378657_379149_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023634.1_379172_380402_+	NA	NA|621aa|down_6|NZ_CP023634.1_380556_382419_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023634.1_382490_382877_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023634.1_382879_383542_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023634.1_383602_384487_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	3	691916-691992	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023634.1_677600_677816_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023634.1_677812_678220_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023634.1_678279_678966_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023634.1_679119_681753_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023634.1_681775_684163_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023634.1_684300_685023_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023634.1_685019_685817_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023634.1_685818_686706_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023634.1_686711_687926_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023634.1_688949_690395_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023634.1_693127_694678_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023634.1_694729_695122_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023634.1_695118_695376_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023634.1_695558_696794_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023634.1_697044_697458_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023634.1_697454_697691_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023634.1_697794_698301_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023634.1_698414_698885_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023634.1_698928_699690_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023634.1_699746_700058_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	4	926492-927439	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927275-927310|927275-927310|927275-927310	NZ_CP023634.1_675019-674984|NZ_CP023634.1_1213624-1213659|NZ_CP023634.1_2423658-2423623	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023634.1_931449_932001_-,NA|81aa|down_8|NZ_CP023634.1_937464_937707_+	NA|685aa|up_9|NZ_CP023634.1_914148_916203_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023634.1_916368_917538_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023634.1_917605_918622_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023634.1_918783_919425_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023634.1_919505_920561_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023634.1_920612_921005_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023634.1_921062_921485_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023634.1_921446_921737_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023634.1_921841_922747_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023634.1_922765_923581_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023634.1_927708_930357_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023634.1_930824_931469_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023634.1_931449_932001_-	NA	NA|218aa|down_3|NZ_CP023634.1_932150_932804_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023634.1_932874_933903_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023634.1_934591_935362_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023634.1_935448_936261_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023634.1_936328_937189_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023634.1_937464_937707_+	NA	NA|431aa|down_9|NZ_CP023634.1_937983_939276_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	5	1191191-1191299	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|394aa|up_9|NZ_CP023634.1_1179269_1180451_+	COG3391, COG3391, Uncharacterized conserved protein [Function unknown]	NA|544aa|up_8|NZ_CP023634.1_1180557_1182189_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_7|NZ_CP023634.1_1182264_1183329_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_6|NZ_CP023634.1_1183381_1183855_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_5|NZ_CP023634.1_1183888_1184752_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|361aa|up_4|NZ_CP023634.1_1185615_1186698_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023634.1_1186778_1187198_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023634.1_1187309_1187876_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023634.1_1187872_1188268_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023634.1_1188295_1190299_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023634.1_1192384_1194148_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023634.1_1194144_1194918_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023634.1_1194929_1195967_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023634.1_1196153_1196990_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023634.1_1197105_1197957_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023634.1_1198030_1199248_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023634.1_1199300_1200245_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023634.1_1200467_1201535_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023634.1_1201591_1202986_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023634.1_1203187_1203910_+	pfam06271, RDD, RDD family
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	6	1211825-1212681	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	73	1212208-1212229|1212253-1212268|1212391-1212412|1212391-1212412|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526	NZ_CP023634.1_2960423-2960402|NZ_CP023634.1_2088479-2088464|NZ_CP023634.1_837325-837346|NZ_CP023634.1_1217520-1217541|NZ_CP023634.1_674683-674665|NZ_CP023634.1_1213351-1213369|NZ_CP023634.1_1217493-1217511|NZ_CP023634.1_1217565-1217583|NZ_CP023634.1_1630547-1630529|NZ_CP023634.1_1633373-1633355|NZ_CP023634.1_1990683-1990665|NZ_CP023634.1_2061407-2061389|NZ_CP023634.1_2061854-2061836|NZ_CP023634.1_2061953-2061935|NZ_CP023634.1_2801972-2801954|NZ_CP023634.1_2805500-2805482|NZ_CP023634.1_1636768-1636750|NZ_CP023634.1_150184-150202|NZ_CP023634.1_333784-333766|NZ_CP023634.1_335203-335185|NZ_CP023634.1_335656-335638|NZ_CP023634.1_335707-335689|NZ_CP023634.1_335716-335698|NZ_CP023634.1_338005-337987|NZ_CP023634.1_338401-338383|NZ_CP023634.1_338430-338448|NZ_CP023634.1_338524-338506|NZ_CP023634.1_363055-363037|NZ_CP023634.1_443355-443337|NZ_CP023634.1_546684-546666|NZ_CP023634.1_623874-623892|NZ_CP023634.1_624096-624114|NZ_CP023634.1_673849-673831|NZ_CP023634.1_840108-840126|NZ_CP023634.1_1090854-1090872|NZ_CP023634.1_1091502-1091520|NZ_CP023634.1_1095559-1095541|NZ_CP023634.1_1212880-1212898|NZ_CP023634.1_1213270-1213288|NZ_CP023634.1_1217913-1217931|NZ_CP023634.1_1489059-1489041|NZ_CP023634.1_1618511-1618493|NZ_CP023634.1_1618964-1618946|NZ_CP023634.1_1635886-1635868|NZ_CP023634.1_1635895-1635877|NZ_CP023634.1_1864175-1864157|NZ_CP023634.1_1864703-1864685|NZ_CP023634.1_1989957-1989939|NZ_CP023634.1_2001319-2001337|NZ_CP023634.1_2088677-2088659|NZ_CP023634.1_2303374-2303356|NZ_CP023634.1_2356826-2356808|NZ_CP023634.1_2419484-2419502|NZ_CP023634.1_2423571-2423553|NZ_CP023634.1_2569065-2569047|NZ_CP023634.1_2693363-2693381|NZ_CP023634.1_2795287-2795269|NZ_CP023634.1_2795869-2795851|NZ_CP023634.1_3054459-3054477|NZ_CP023634.1_3054558-3054576|NZ_CP023634.1_3705355-3705373|NZ_CP023634.1_3737332-3737314|NZ_CP023634.1_3737950-3737932|NZ_CP023634.1_3738193-3738175|NZ_CP023634.1_3738326-3738308|NZ_CP023634.1_3802189-3802207|NZ_CP023634.1_3802372-3802390|NZ_CP023634.1_3802540-3802558|NZ_CP023634.1_3930332-3930350|NZ_CP023634.1_3932062-3932080|NZ_CP023634.1_3940569-3940587|NZ_CP023634.1_4031548-4031530|NZ_CP023634.1_4094074-4094092	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023634.1_1207257_1207524_+,NA|61aa|down_3|NZ_CP023634.1_1215100_1215283_+,NA|35aa|down_4|NZ_CP023634.1_1215392_1215497_+	NA|465aa|up_9|NZ_CP023634.1_1201591_1202986_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023634.1_1203187_1203910_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023634.1_1203941_1205108_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023634.1_1205178_1205673_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023634.1_1205858_1206293_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|296aa|up_4|NZ_CP023634.1_1206394_1207282_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023634.1_1207257_1207524_+	NA	NA|674aa|up_2|NZ_CP023634.1_1207510_1209532_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023634.1_1209630_1210359_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023634.1_1210469_1211258_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023634.1_1213915_1214236_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023634.1_1214388_1214823_+	pfam00934, PE, PE family	NA|55aa|down_2|NZ_CP023634.1_1214924_1215089_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023634.1_1215100_1215283_+	NA	NA|35aa|down_4|NZ_CP023634.1_1215392_1215497_+	NA	NA|152aa|down_5|NZ_CP023634.1_1215474_1215930_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023634.1_1216344_1218906_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023634.1_1219123_1220062_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023634.1_1220449_1221730_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023634.1_1221834_1222662_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	7	1572034-1573106	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP023634.1_1563797_1564115_+,NA	NA|103aa|up_9|NZ_CP023634.1_1561312_1561621_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023634.1_1561617_1563237_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023634.1_1563797_1564115_+	NA	NA|209aa|up_6|NZ_CP023634.1_1564249_1564876_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023634.1_1564941_1565274_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023634.1_1565289_1566546_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023634.1_1566673_1567885_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023634.1_1567957_1569436_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023634.1_1569432_1570818_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023634.1_1570895_1571930_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023634.1_1573960_1574362_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023634.1_1574358_1574616_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023634.1_1574698_1575658_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023634.1_1575682_1576645_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023634.1_1576778_1577381_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023634.1_1577461_1579429_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023634.1_1579446_1580271_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023634.1_1580439_1580922_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023634.1_1580993_1581818_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023634.1_1582014_1582953_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	8	1636464-1636690	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP023634.1_1622972_1623086_-,NA|137aa|up_7|NZ_CP023634.1_1623135_1623546_-,NA|288aa|down_2|NZ_CP023634.1_1640528_1641392_+	NA|162aa|up_9|NZ_CP023634.1_1622055_1622541_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP023634.1_1622972_1623086_-	NA	NA|137aa|up_7|NZ_CP023634.1_1623135_1623546_-	NA	NA|248aa|up_6|NZ_CP023634.1_1623562_1624306_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP023634.1_1624302_1625214_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP023634.1_1625266_1626811_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP023634.1_1626807_1627929_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP023634.1_1627945_1630048_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP023634.1_1630486_1634476_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP023634.1_1634877_1635804_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP023634.1_1638229_1639495_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP023634.1_1639522_1640509_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP023634.1_1640528_1641392_+	NA	NA|311aa|down_3|NZ_CP023634.1_1641341_1642274_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP023634.1_1642385_1643171_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP023634.1_1643167_1644109_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP023634.1_1644211_1645987_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP023634.1_1646034_1646841_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP023634.1_1646837_1649378_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP023634.1_1649374_1650568_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	9	2088149-2088403	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088230-2088247|2088230-2088247|2088320-2088337	NZ_CP023634.1_401080-401063|NZ_CP023634.1_607329-607312|NZ_CP023634.1_3450056-3450039	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023634.1_2087508_2087772_-,NA	NA|165aa|up_9|NZ_CP023634.1_2073802_2074297_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023634.1_2074700_2075378_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023634.1_2075736_2078562_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023634.1_2078788_2079649_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023634.1_2079689_2080556_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023634.1_2080560_2082447_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023634.1_2082462_2084496_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023634.1_2084615_2086841_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023634.1_2087116_2087512_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023634.1_2087508_2087772_-	NA	NA|346aa|down_0|NZ_CP023634.1_2089543_2090581_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023634.1_2090580_2091948_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023634.1_2092121_2093558_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|486aa|down_3|NZ_CP023634.1_2093593_2095051_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023634.1_2095080_2096031_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023634.1_2096045_2096462_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023634.1_2096739_2097162_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023634.1_2097210_2097513_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023634.1_2097509_2097824_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023634.1_2097823_2099557_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	10	2163240-2163344	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023634.1_2159784_2160192_-,NA|127aa|down_5|NZ_CP023634.1_2176412_2176793_-	NA|216aa|up_9|NZ_CP023634.1_2153098_2153746_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023634.1_2153752_2155975_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023634.1_2156012_2156456_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023634.1_2156569_2157163_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023634.1_2157245_2157851_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023634.1_2157950_2158955_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023634.1_2159054_2159807_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023634.1_2159784_2160192_-	NA	NA|368aa|up_1|NZ_CP023634.1_2160326_2161430_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023634.1_2161429_2162626_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|155aa|down_0|NZ_CP023634.1_2170923_2171388_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023634.1_2171485_2172349_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023634.1_2172386_2173658_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023634.1_2173929_2175045_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023634.1_2175035_2176376_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023634.1_2176412_2176793_-	NA	NA|621aa|down_6|NZ_CP023634.1_2176949_2178812_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023634.1_2178819_2179299_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023634.1_2179535_2180309_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023634.1_2180312_2181080_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	11	2168678-2168897	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP023634.1_2159784_2160192_-,NA|127aa|down_5|NZ_CP023634.1_2176412_2176793_-	NA|741aa|up_9|NZ_CP023634.1_2153752_2155975_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023634.1_2156012_2156456_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023634.1_2156569_2157163_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023634.1_2157245_2157851_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023634.1_2157950_2158955_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023634.1_2159054_2159807_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023634.1_2159784_2160192_-	NA	NA|368aa|up_2|NZ_CP023634.1_2160326_2161430_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023634.1_2161429_2162626_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023634.1_2162795_2167175_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023634.1_2170923_2171388_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023634.1_2171485_2172349_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023634.1_2172386_2173658_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023634.1_2173929_2175045_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023634.1_2175035_2176376_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023634.1_2176412_2176793_-	NA	NA|621aa|down_6|NZ_CP023634.1_2176949_2178812_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023634.1_2178819_2179299_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023634.1_2179535_2180309_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023634.1_2180312_2181080_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	12	3119050-3120404	3,8,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-D,Type III-C,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	16,17,18	18	TypeIII-B,TypeIII-D,TypeIII-C,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023634.1_3112329_3112584_-,NA|135aa|up_7|NZ_CP023634.1_3112731_3113136_+,NA|64aa|up_6|NZ_CP023634.1_3113132_3113324_+,NA|86aa|up_4|NZ_CP023634.1_3114910_3115168_+,NA|104aa|up_3|NZ_CP023634.1_3115272_3115584_+,NA|203aa|up_2|NZ_CP023634.1_3116003_3116612_+,NA	NA|92aa|up_9|NZ_CP023634.1_3111878_3112154_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023634.1_3112329_3112584_-	NA	NA|135aa|up_7|NZ_CP023634.1_3112731_3113136_+	NA	NA|64aa|up_6|NZ_CP023634.1_3113132_3113324_+	NA	NA|385aa|up_5|NZ_CP023634.1_3113522_3114677_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023634.1_3114910_3115168_+	NA	NA|104aa|up_3|NZ_CP023634.1_3115272_3115584_+	NA	NA|203aa|up_2|NZ_CP023634.1_3116003_3116612_+	NA	NA|470aa|up_1|NZ_CP023634.1_3116682_3118092_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023634.1_3118088_3118901_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023634.1_3120430_3121692_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023634.1_3123489_3123831_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023634.1_3123831_3124848_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023634.1_3124860_3126009_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023634.1_3126104_3127232_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023634.1_3127228_3128137_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023634.1_3128117_3128828_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023634.1_3128837_3129212_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_8|NZ_CP023634.1_3129208_3131638_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023634.1_3131634_3132357_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	13	3121727-3123441	9,4,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-D,Type III-C,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-B,TypeIII-D,TypeIII-C,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023634.1_3112329_3112584_-,NA|135aa|up_8|NZ_CP023634.1_3112731_3113136_+,NA|64aa|up_7|NZ_CP023634.1_3113132_3113324_+,NA|86aa|up_5|NZ_CP023634.1_3114910_3115168_+,NA|104aa|up_4|NZ_CP023634.1_3115272_3115584_+,NA|203aa|up_3|NZ_CP023634.1_3116003_3116612_+,NA	NA|85aa|up_9|NZ_CP023634.1_3112329_3112584_-	NA	NA|135aa|up_8|NZ_CP023634.1_3112731_3113136_+	NA	NA|64aa|up_7|NZ_CP023634.1_3113132_3113324_+	NA	NA|385aa|up_6|NZ_CP023634.1_3113522_3114677_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023634.1_3114910_3115168_+	NA	NA|104aa|up_4|NZ_CP023634.1_3115272_3115584_+	NA	NA|203aa|up_3|NZ_CP023634.1_3116003_3116612_+	NA	NA|470aa|up_2|NZ_CP023634.1_3116682_3118092_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023634.1_3118088_3118901_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023634.1_3120430_3121692_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023634.1_3123489_3123831_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023634.1_3123831_3124848_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023634.1_3124860_3126009_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023634.1_3126104_3127232_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023634.1_3127228_3128137_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023634.1_3128117_3128828_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023634.1_3128837_3129212_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_7|NZ_CP023634.1_3129208_3131638_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023634.1_3131634_3132357_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023634.1_3132756_3133302_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	14	3740520-3741061	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023634.1_3755162_3755450_-,NA|87aa|down_9|NZ_CP023634.1_3768570_3768831_-	NA|282aa|up_9|NZ_CP023634.1_3719777_3720623_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023634.1_3721097_3721538_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023634.1_3721571_3722441_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023634.1_3722461_3723472_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023634.1_3723756_3724389_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023634.1_3724455_3725685_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023634.1_3725967_3727317_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023634.1_3727328_3728468_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023634.1_3728464_3729196_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023634.1_3729204_3736776_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023634.1_3743032_3743290_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023634.1_3743545_3753019_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023634.1_3753644_3754091_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023634.1_3754127_3754868_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023634.1_3755162_3755450_-	NA	NA|3717aa|down_5|NZ_CP023634.1_3755786_3766937_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023634.1_3767180_3767975_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023634.1_3768056_3768428_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023634.1_3768325_3768544_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023634.1_3768570_3768831_-	NA
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	15	3948177-3949928	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCNNCGGCGGNNNCGGCGG	36	2	9	3948768-3948803|3948768-3948803|3948768-3948803|3948768-3948803|3948768-3948803|3949659-3949685|3949659-3949685|3949659-3949685|3949659-3949685	NZ_CP023634.1_3946884-3946919|NZ_CP023634.1_3947226-3947261|NZ_CP023634.1_3947817-3947852|NZ_CP023634.1_3948168-3948203|NZ_CP023634.1_3932617-3932652|NZ_CP023634.1_361995-362021|NZ_CP023634.1_3941070-3941096|NZ_CP023634.1_3941406-3941432|NZ_CP023634.1_3941752-3941778	NA	21	21	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP023634.1_3953243_3954083_+	NA|318aa|up_9|NZ_CP023634.1_3920899_3921853_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP023634.1_3921877_3922069_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP023634.1_3922283_3923486_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP023634.1_3923510_3924632_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP023634.1_3924702_3926211_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1382aa|up_4|NZ_CP023634.1_3926381_3930527_+	pfam00934, PE, PE family	NA|1902aa|up_3|NZ_CP023634.1_3930817_3936523_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP023634.1_3936689_3938237_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP023634.1_3938233_3939070_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP023634.1_3944904_3945561_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023634.1_3950636_3952283_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023634.1_3952356_3953148_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023634.1_3953243_3954083_+	NA	NA|399aa|down_3|NZ_CP023634.1_3954137_3955334_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023634.1_3955362_3956073_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023634.1_3956137_3957181_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023634.1_3957333_3958245_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023634.1_3958260_3959325_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023634.1_3959341_3960526_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023634.1_3960567_3961599_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002448095.1_ASM244809v1	NZ_CP023634	Mycobacterium tuberculosis strain TBDM2487 chromosome, complete genome	16	4110491-4110579	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023634.1_4101077_4101848_-,NA|119aa|up_3|NZ_CP023634.1_4106982_4107339_+,NA|52aa|up_2|NZ_CP023634.1_4107438_4107594_+,NA|233aa|up_0|NZ_CP023634.1_4109595_4110294_-,NA|126aa|down_6|NZ_CP023634.1_4115814_4116192_+	NA|288aa|up_9|NZ_CP023634.1_4099459_4100323_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023634.1_4101077_4101848_-	NA	NA|549aa|up_7|NZ_CP023634.1_4101844_4103491_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023634.1_4103487_4104351_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023634.1_4104343_4105270_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023634.1_4105271_4106897_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023634.1_4106982_4107339_+	NA	NA|52aa|up_2|NZ_CP023634.1_4107438_4107594_+	NA	NA|652aa|up_1|NZ_CP023634.1_4107604_4109560_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023634.1_4109595_4110294_-	NA	NA|173aa|down_0|NZ_CP023634.1_4110639_4111158_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023634.1_4111158_4112142_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023634.1_4112134_4113328_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023634.1_4113333_4114155_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023634.1_4114286_4114970_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023634.1_4114969_4115707_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023634.1_4115814_4116192_+	NA	NA|225aa|down_7|NZ_CP023634.1_4116290_4116965_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023634.1_4117070_4117865_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023634.1_4117871_4118327_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
