assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	1	366463-367161	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366751-366792|366826-366858	NZ_CP023633.1_374782-374823|NZ_CP023633.1_373597-373629	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023633.1_363475_363778_+,NA|161aa|down_1|NZ_CP023633.1_376571_377054_-,NA|410aa|down_5|NZ_CP023633.1_379170_380400_+	NA|262aa|up_9|NZ_CP023633.1_358170_358956_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023633.1_358944_359748_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023633.1_359757_361155_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023633.1_361333_363109_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023633.1_363251_363479_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023633.1_363475_363778_+	NA	NA|74aa|up_3|NZ_CP023633.1_363825_364047_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023633.1_364043_364469_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023633.1_364604_365237_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023633.1_365233_366142_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023633.1_375912_376584_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023633.1_376571_377054_-	NA	NA|239aa|down_2|NZ_CP023633.1_377111_377828_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023633.1_377929_378586_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023633.1_378655_379147_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023633.1_379170_380400_+	NA	NA|621aa|down_6|NZ_CP023633.1_380554_382417_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023633.1_382488_382875_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023633.1_382877_383540_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023633.1_383600_384485_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	2	691951-692027	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023633.1_677635_677851_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023633.1_677847_678255_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023633.1_678314_679001_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023633.1_679154_681788_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023633.1_681810_684198_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023633.1_684335_685058_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023633.1_685054_685852_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023633.1_685853_686741_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023633.1_686746_687961_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023633.1_688984_690430_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023633.1_693162_694713_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023633.1_694764_695157_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023633.1_695153_695411_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023633.1_695593_696829_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023633.1_697079_697493_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023633.1_697489_697726_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023633.1_697829_698336_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023633.1_698449_698920_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023633.1_698963_699725_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023633.1_699781_700093_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	3	926524-927471	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927307-927342|927307-927342|927307-927342	NZ_CP023633.1_675054-675019|NZ_CP023633.1_1213624-1213659|NZ_CP023633.1_2423584-2423549	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023633.1_931481_932033_-,NA|81aa|down_8|NZ_CP023633.1_937496_937739_+	NA|685aa|up_9|NZ_CP023633.1_914160_916215_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023633.1_916380_917550_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023633.1_917637_918654_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|220aa|up_6|NZ_CP023633.1_918815_919475_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023633.1_919537_920593_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023633.1_920644_921037_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023633.1_921094_921517_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023633.1_921478_921769_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023633.1_921873_922779_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023633.1_922797_923613_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023633.1_927740_930389_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023633.1_930856_931501_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023633.1_931481_932033_-	NA	NA|218aa|down_3|NZ_CP023633.1_932182_932836_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023633.1_932906_933935_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023633.1_934623_935394_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023633.1_935480_936293_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023633.1_936360_937221_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023633.1_937496_937739_+	NA	NA|431aa|down_9|NZ_CP023633.1_938015_939308_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	4	964485-964736	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGT	63	1	1	964658-964713	NZ_CP023633.1_964786-964841	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|67aa|up_3|NZ_CP023633.1_962583_962784_+,NA	NA|158aa|up_9|NZ_CP023633.1_953160_953634_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|398aa|up_8|NZ_CP023633.1_953630_954824_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|404aa|up_7|NZ_CP023633.1_954980_956192_+	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase	NA|721aa|up_6|NZ_CP023633.1_956196_958359_+	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB	NA|543aa|up_5|NZ_CP023633.1_958426_960055_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|757aa|up_4|NZ_CP023633.1_960245_962516_-	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|67aa|up_3|NZ_CP023633.1_962583_962784_+	NA	NA|168aa|up_2|NZ_CP023633.1_962793_963297_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|161aa|up_1|NZ_CP023633.1_963293_963776_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|142aa|up_0|NZ_CP023633.1_963772_964198_+	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism]	NA|93aa|down_0|NZ_CP023633.1_965886_966165_-	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins	NA|361aa|down_1|NZ_CP023633.1_966168_967251_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|130aa|down_2|NZ_CP023633.1_967247_967637_-	PRK11770, PRK11770, YccF domain-containing protein	NA|136aa|down_3|NZ_CP023633.1_967801_968209_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|610aa|down_4|NZ_CP023633.1_968327_970157_-	pfam00934, PE, PE family	NA|651aa|down_5|NZ_CP023633.1_970417_972370_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|387aa|down_6|NZ_CP023633.1_972458_973619_-	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|163aa|down_7|NZ_CP023633.1_973718_974207_-	pfam10969, DUF2771, Protein of unknown function (DUF2771)	NA|549aa|down_8|NZ_CP023633.1_974203_975850_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|263aa|down_9|NZ_CP023633.1_975987_976776_+	pfam11228, DUF3027, Protein of unknown function (DUF3027)
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	5	1191192-1191300	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023633.1_1180584_1182216_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023633.1_1182291_1183356_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023633.1_1183408_1183882_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023633.1_1183915_1184779_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023633.1_1184783_1185641_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023633.1_1185641_1186724_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023633.1_1186804_1187224_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023633.1_1187335_1187902_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023633.1_1187898_1188294_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|632aa|up_0|NZ_CP023633.1_1188401_1190297_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023633.1_1192385_1194149_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023633.1_1194145_1194919_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023633.1_1194930_1195968_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023633.1_1196154_1196991_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023633.1_1197106_1197958_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023633.1_1198031_1199249_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|356aa|down_6|NZ_CP023633.1_1200467_1201535_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_7|NZ_CP023633.1_1201591_1202986_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_8|NZ_CP023633.1_1203187_1203910_+	pfam06271, RDD, RDD family	NA|389aa|down_9|NZ_CP023633.1_1203941_1205108_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	6	1211825-1212681	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	75	1212208-1212229|1212253-1212268|1212391-1212412|1212391-1212412|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526	NZ_CP023633.1_2960349-2960328|NZ_CP023633.1_2088461-2088446|NZ_CP023633.1_837347-837368|NZ_CP023633.1_1217519-1217540|NZ_CP023633.1_674718-674700|NZ_CP023633.1_1213351-1213369|NZ_CP023633.1_1217492-1217510|NZ_CP023633.1_1217564-1217582|NZ_CP023633.1_1630556-1630538|NZ_CP023633.1_1633382-1633364|NZ_CP023633.1_1990664-1990646|NZ_CP023633.1_2061389-2061371|NZ_CP023633.1_2061836-2061818|NZ_CP023633.1_2061935-2061917|NZ_CP023633.1_2801898-2801880|NZ_CP023633.1_2805426-2805408|NZ_CP023633.1_1636777-1636759|NZ_CP023633.1_150188-150206|NZ_CP023633.1_333800-333782|NZ_CP023633.1_335219-335201|NZ_CP023633.1_335672-335654|NZ_CP023633.1_335723-335705|NZ_CP023633.1_335732-335714|NZ_CP023633.1_338003-337985|NZ_CP023633.1_338132-338114|NZ_CP023633.1_338399-338381|NZ_CP023633.1_338428-338446|NZ_CP023633.1_338522-338504|NZ_CP023633.1_363053-363035|NZ_CP023633.1_443377-443359|NZ_CP023633.1_546718-546700|NZ_CP023633.1_623909-623927|NZ_CP023633.1_624131-624149|NZ_CP023633.1_673884-673866|NZ_CP023633.1_840130-840148|NZ_CP023633.1_1090890-1090908|NZ_CP023633.1_1091538-1091556|NZ_CP023633.1_1095596-1095578|NZ_CP023633.1_1212880-1212898|NZ_CP023633.1_1213270-1213288|NZ_CP023633.1_1217912-1217930|NZ_CP023633.1_1489088-1489070|NZ_CP023633.1_1618520-1618502|NZ_CP023633.1_1618973-1618955|NZ_CP023633.1_1635895-1635877|NZ_CP023633.1_1635904-1635886|NZ_CP023633.1_1864177-1864159|NZ_CP023633.1_1864705-1864687|NZ_CP023633.1_1989938-1989920|NZ_CP023633.1_2001301-2001319|NZ_CP023633.1_2088659-2088641|NZ_CP023633.1_2303358-2303340|NZ_CP023633.1_2356810-2356792|NZ_CP023633.1_2419410-2419428|NZ_CP023633.1_2423497-2423479|NZ_CP023633.1_2568990-2568972|NZ_CP023633.1_2693289-2693307|NZ_CP023633.1_2795213-2795195|NZ_CP023633.1_2795795-2795777|NZ_CP023633.1_3054386-3054404|NZ_CP023633.1_3054485-3054503|NZ_CP023633.1_3705301-3705319|NZ_CP023633.1_3737278-3737260|NZ_CP023633.1_3737875-3737857|NZ_CP023633.1_3738118-3738100|NZ_CP023633.1_3738251-3738233|NZ_CP023633.1_3802114-3802132|NZ_CP023633.1_3802297-3802315|NZ_CP023633.1_3802465-3802483|NZ_CP023633.1_3930276-3930294|NZ_CP023633.1_3932006-3932024|NZ_CP023633.1_3940513-3940531|NZ_CP023633.1_3948508-3948526|NZ_CP023633.1_4031489-4031471|NZ_CP023633.1_4094009-4094027	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023633.1_1207257_1207524_+,NA|61aa|down_3|NZ_CP023633.1_1215099_1215282_+,NA|35aa|down_4|NZ_CP023633.1_1215391_1215496_+	NA|465aa|up_9|NZ_CP023633.1_1201591_1202986_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023633.1_1203187_1203910_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023633.1_1203941_1205108_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023633.1_1205178_1205673_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023633.1_1205858_1206293_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023633.1_1206394_1207261_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023633.1_1207257_1207524_+	NA	NA|674aa|up_2|NZ_CP023633.1_1207510_1209532_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023633.1_1209630_1210359_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023633.1_1210469_1211258_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023633.1_1213914_1214235_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023633.1_1214387_1214822_+	pfam00934, PE, PE family	NA|55aa|down_2|NZ_CP023633.1_1214923_1215088_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023633.1_1215099_1215282_+	NA	NA|35aa|down_4|NZ_CP023633.1_1215391_1215496_+	NA	NA|152aa|down_5|NZ_CP023633.1_1215473_1215929_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023633.1_1216343_1218905_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023633.1_1219122_1220061_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023633.1_1220448_1221729_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023633.1_1221833_1222661_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	7	1572064-1573136	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP023633.1_1563827_1564145_+,NA	NA|103aa|up_9|NZ_CP023633.1_1561342_1561651_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023633.1_1561647_1563267_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023633.1_1563827_1564145_+	NA	NA|209aa|up_6|NZ_CP023633.1_1564279_1564906_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023633.1_1564971_1565304_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023633.1_1565319_1566576_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023633.1_1566703_1567915_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023633.1_1567987_1569466_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023633.1_1569462_1570848_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023633.1_1570925_1571960_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023633.1_1573990_1574392_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023633.1_1574388_1574646_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023633.1_1574728_1575688_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023633.1_1575712_1576675_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023633.1_1576808_1577411_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023633.1_1577491_1579459_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023633.1_1579476_1580301_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023633.1_1580469_1580952_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023633.1_1581023_1581848_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023633.1_1582044_1582983_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	8	1636473-1636699	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP023633.1_1622981_1623095_-,NA|137aa|up_7|NZ_CP023633.1_1623144_1623555_-,NA|288aa|down_2|NZ_CP023633.1_1640531_1641395_+	NA|162aa|up_9|NZ_CP023633.1_1622064_1622550_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP023633.1_1622981_1623095_-	NA	NA|137aa|up_7|NZ_CP023633.1_1623144_1623555_-	NA	NA|248aa|up_6|NZ_CP023633.1_1623571_1624315_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP023633.1_1624311_1625223_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP023633.1_1625275_1626820_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP023633.1_1626816_1627938_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP023633.1_1627954_1630057_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP023633.1_1630495_1634485_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP023633.1_1634886_1635813_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP023633.1_1638232_1639498_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP023633.1_1639525_1640512_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP023633.1_1640531_1641395_+	NA	NA|311aa|down_3|NZ_CP023633.1_1641344_1642277_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP023633.1_1642388_1643174_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP023633.1_1643170_1644112_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP023633.1_1644214_1645990_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP023633.1_1646037_1646844_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP023633.1_1646840_1649381_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP023633.1_1649377_1650571_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	9	2088131-2088385	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088212-2088229|2088212-2088229|2088302-2088319	NZ_CP023633.1_401078-401061|NZ_CP023633.1_607364-607347|NZ_CP023633.1_3450002-3449985	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023633.1_2087490_2087754_-,NA	NA|165aa|up_9|NZ_CP023633.1_2073784_2074279_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023633.1_2074682_2075360_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023633.1_2075718_2078544_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023633.1_2078770_2079631_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023633.1_2079671_2080538_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023633.1_2080542_2082429_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023633.1_2082444_2084478_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023633.1_2084597_2086823_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023633.1_2087098_2087494_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023633.1_2087490_2087754_-	NA	NA|346aa|down_0|NZ_CP023633.1_2089522_2090560_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023633.1_2090559_2091927_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023633.1_2092100_2093537_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023633.1_2093572_2095024_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023633.1_2095053_2096004_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023633.1_2096018_2096435_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023633.1_2096712_2097135_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023633.1_2097183_2097486_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023633.1_2097482_2097797_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023633.1_2097796_2099530_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	10	2163222-2163326	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023633.1_2159766_2160174_-,NA|127aa|down_6|NZ_CP023633.1_2176395_2176776_-	NA|216aa|up_9|NZ_CP023633.1_2153080_2153728_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023633.1_2153734_2155957_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023633.1_2155994_2156438_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023633.1_2156551_2157145_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023633.1_2157227_2157833_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023633.1_2157932_2158937_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023633.1_2159036_2159789_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023633.1_2159766_2160174_-	NA	NA|368aa|up_1|NZ_CP023633.1_2160308_2161412_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023633.1_2161411_2162608_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023633.1_2167494_2170458_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023633.1_2170906_2171371_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023633.1_2171468_2172332_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023633.1_2172369_2173641_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023633.1_2173912_2175028_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023633.1_2175018_2176359_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023633.1_2176395_2176776_-	NA	NA|621aa|down_7|NZ_CP023633.1_2176932_2178795_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023633.1_2178802_2179282_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023633.1_2179518_2180292_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	11	2168660-2168879	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP023633.1_2159766_2160174_-,NA|127aa|down_5|NZ_CP023633.1_2176395_2176776_-	NA|741aa|up_9|NZ_CP023633.1_2153734_2155957_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023633.1_2155994_2156438_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023633.1_2156551_2157145_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023633.1_2157227_2157833_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023633.1_2157932_2158937_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023633.1_2159036_2159789_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023633.1_2159766_2160174_-	NA	NA|368aa|up_2|NZ_CP023633.1_2160308_2161412_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023633.1_2161411_2162608_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023633.1_2162777_2167157_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023633.1_2170906_2171371_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023633.1_2171468_2172332_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023633.1_2172369_2173641_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023633.1_2173912_2175028_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023633.1_2175018_2176359_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023633.1_2176395_2176776_-	NA	NA|621aa|down_6|NZ_CP023633.1_2176932_2178795_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023633.1_2178802_2179282_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023633.1_2179518_2180292_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023633.1_2180295_2181063_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	12	3118977-3120331	3,8,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-A,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	16,17,18	18	TypeIII-D,TypeIII-A,TypeIII-C,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023633.1_3112256_3112511_-,NA|135aa|up_7|NZ_CP023633.1_3112658_3113063_+,NA|64aa|up_6|NZ_CP023633.1_3113059_3113251_+,NA|86aa|up_4|NZ_CP023633.1_3114837_3115095_+,NA|104aa|up_3|NZ_CP023633.1_3115199_3115511_+,NA|203aa|up_2|NZ_CP023633.1_3115930_3116539_+,NA	NA|92aa|up_9|NZ_CP023633.1_3111805_3112081_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023633.1_3112256_3112511_-	NA	NA|135aa|up_7|NZ_CP023633.1_3112658_3113063_+	NA	NA|64aa|up_6|NZ_CP023633.1_3113059_3113251_+	NA	NA|385aa|up_5|NZ_CP023633.1_3113449_3114604_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023633.1_3114837_3115095_+	NA	NA|104aa|up_3|NZ_CP023633.1_3115199_3115511_+	NA	NA|203aa|up_2|NZ_CP023633.1_3115930_3116539_+	NA	NA|470aa|up_1|NZ_CP023633.1_3116609_3118019_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023633.1_3118015_3118828_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023633.1_3120357_3121619_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023633.1_3123416_3123758_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023633.1_3123758_3124775_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023633.1_3124787_3125936_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023633.1_3126031_3127159_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023633.1_3127155_3128064_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023633.1_3128044_3128755_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023633.1_3128764_3129139_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023633.1_3129135_3131574_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023633.1_3131570_3132293_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	13	3121654-3123368	9,4,4,5	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-A,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A:II-B,III-A	23,23,20,20	23	TypeIII-D,TypeIII-A,TypeIII-C,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023633.1_3112256_3112511_-,NA|135aa|up_8|NZ_CP023633.1_3112658_3113063_+,NA|64aa|up_7|NZ_CP023633.1_3113059_3113251_+,NA|86aa|up_5|NZ_CP023633.1_3114837_3115095_+,NA|104aa|up_4|NZ_CP023633.1_3115199_3115511_+,NA|203aa|up_3|NZ_CP023633.1_3115930_3116539_+,NA	NA|85aa|up_9|NZ_CP023633.1_3112256_3112511_-	NA	NA|135aa|up_8|NZ_CP023633.1_3112658_3113063_+	NA	NA|64aa|up_7|NZ_CP023633.1_3113059_3113251_+	NA	NA|385aa|up_6|NZ_CP023633.1_3113449_3114604_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023633.1_3114837_3115095_+	NA	NA|104aa|up_4|NZ_CP023633.1_3115199_3115511_+	NA	NA|203aa|up_3|NZ_CP023633.1_3115930_3116539_+	NA	NA|470aa|up_2|NZ_CP023633.1_3116609_3118019_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023633.1_3118015_3118828_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023633.1_3120357_3121619_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023633.1_3123416_3123758_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023633.1_3123758_3124775_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023633.1_3124787_3125936_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023633.1_3126031_3127159_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023633.1_3127155_3128064_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023633.1_3128044_3128755_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023633.1_3128764_3129139_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023633.1_3129135_3131574_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023633.1_3131570_3132293_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023633.1_3132692_3133238_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	14	3740445-3740986	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023633.1_3755087_3755375_-,NA|87aa|down_9|NZ_CP023633.1_3768495_3768756_-	NA|282aa|up_9|NZ_CP023633.1_3719723_3720569_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023633.1_3721043_3721484_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023633.1_3721517_3722387_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023633.1_3722407_3723418_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023633.1_3723702_3724335_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023633.1_3724401_3725631_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023633.1_3725913_3727263_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023633.1_3727274_3728414_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023633.1_3728410_3729142_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023633.1_3729150_3736722_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023633.1_3742957_3743215_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023633.1_3743470_3752944_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023633.1_3753569_3754016_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023633.1_3754052_3754793_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023633.1_3755087_3755375_-	NA	NA|3717aa|down_5|NZ_CP023633.1_3755711_3766862_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023633.1_3767105_3767900_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023633.1_3767981_3768353_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023633.1_3768250_3768469_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023633.1_3768495_3768756_-	NA
GCF_002448075.1_ASM244807v1	NZ_CP023633	Mycobacterium tuberculosis strain TBDM2444 chromosome, complete genome	15	4110426-4110514	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023633.1_4101012_4101783_-,NA|119aa|up_3|NZ_CP023633.1_4106917_4107274_+,NA|52aa|up_2|NZ_CP023633.1_4107373_4107529_+,NA|233aa|up_0|NZ_CP023633.1_4109530_4110229_-,NA|126aa|down_6|NZ_CP023633.1_4115749_4116127_+	NA|288aa|up_9|NZ_CP023633.1_4099394_4100258_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023633.1_4101012_4101783_-	NA	NA|549aa|up_7|NZ_CP023633.1_4101779_4103426_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023633.1_4103422_4104286_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023633.1_4104278_4105205_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023633.1_4105206_4106832_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023633.1_4106917_4107274_+	NA	NA|52aa|up_2|NZ_CP023633.1_4107373_4107529_+	NA	NA|652aa|up_1|NZ_CP023633.1_4107539_4109495_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023633.1_4109530_4110229_-	NA	NA|173aa|down_0|NZ_CP023633.1_4110574_4111093_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023633.1_4111093_4112077_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023633.1_4112069_4113263_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023633.1_4113268_4114090_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023633.1_4114221_4114905_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023633.1_4114904_4115642_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023633.1_4115749_4116127_+	NA	NA|225aa|down_7|NZ_CP023633.1_4116225_4116900_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023633.1_4117005_4117800_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023633.1_4117806_4118262_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
