assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	1	366447-367145	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366735-366776|366810-366842	NZ_CP023629.1_374766-374807|NZ_CP023629.1_373581-373613	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023629.1_363459_363762_+,NA|161aa|down_1|NZ_CP023629.1_376555_377038_-,NA|410aa|down_5|NZ_CP023629.1_379154_380384_+	NA|262aa|up_9|NZ_CP023629.1_358154_358940_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023629.1_358928_359732_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023629.1_359741_361139_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023629.1_361317_363093_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023629.1_363235_363463_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023629.1_363459_363762_+	NA	NA|74aa|up_3|NZ_CP023629.1_363809_364031_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023629.1_364027_364453_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023629.1_364588_365221_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023629.1_365217_366126_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023629.1_375896_376568_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023629.1_376555_377038_-	NA	NA|239aa|down_2|NZ_CP023629.1_377095_377812_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023629.1_377913_378570_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023629.1_378639_379131_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023629.1_379154_380384_+	NA	NA|621aa|down_6|NZ_CP023629.1_380538_382401_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023629.1_382472_382859_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023629.1_382861_383524_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023629.1_383584_384469_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	2	672550-672661	2	CRISPRCasFinder	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CCGCCGTTGCCGCCGTTGCCGCCG	24	1	2	672616-672636|672616-672636	NZ_CP023629.1_840063-840043|NZ_CP023629.1_1870441-1870461	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|114aa|up_6|NZ_CP023629.1_664928_665270_-,NA|56aa|up_5|NZ_CP023629.1_665320_665488_-,NA|164aa|down_1|NZ_CP023629.1_677011_677503_-	NA|89aa|up_9|NZ_CP023629.1_660889_661156_+	pfam08940, DUF1918, Domain of unknown function (DUF1918)	NA|693aa|up_8|NZ_CP023629.1_661181_663260_+	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase	NA|444aa|up_7|NZ_CP023629.1_663373_664705_-	COG1926, COG1926, Predicted phosphoribosyltransferases [General function prediction only]	NA|114aa|up_6|NZ_CP023629.1_664928_665270_-	NA	NA|56aa|up_5|NZ_CP023629.1_665320_665488_-	NA	NA|464aa|up_4|NZ_CP023629.1_665737_667129_-	PRK12484, PRK12484, nicotinate phosphoribosyltransferase; Provisional	NA|381aa|up_3|NZ_CP023629.1_667138_668281_-	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]	NA|389aa|up_2|NZ_CP023629.1_668465_669632_-	PRK07588, PRK07588, FAD-binding domain	csa3|435aa|up_1|NZ_CP023629.1_669734_671039_+	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein	NA|262aa|up_0|NZ_CP023629.1_671052_671838_+	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only]	NA|253aa|down_0|NZ_CP023629.1_676124_676883_+	pfam01927, Mut7-C, Mut7-C RNAse domain	NA|164aa|down_1|NZ_CP023629.1_677011_677503_-	NA	NA|72aa|down_2|NZ_CP023629.1_677596_677812_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|down_3|NZ_CP023629.1_677808_678216_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|down_4|NZ_CP023629.1_678275_678962_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|down_5|NZ_CP023629.1_679115_681749_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|down_6|NZ_CP023629.1_681771_684159_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|down_7|NZ_CP023629.1_684296_685019_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|down_8|NZ_CP023629.1_685015_685813_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|down_9|NZ_CP023629.1_685814_686702_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	3	672730-673707	3	CRISPRCasFinder	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CCGCCGTTGCCGCCGTTGCCGCCG	24	1	2	673186-673206|673186-673206	NZ_CP023629.1_2031561-2031581|NZ_CP023629.1_3930357-3930337	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|114aa|up_6|NZ_CP023629.1_664928_665270_-,NA|56aa|up_5|NZ_CP023629.1_665320_665488_-,NA|164aa|down_1|NZ_CP023629.1_677011_677503_-	NA|89aa|up_9|NZ_CP023629.1_660889_661156_+	pfam08940, DUF1918, Domain of unknown function (DUF1918)	NA|693aa|up_8|NZ_CP023629.1_661181_663260_+	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase	NA|444aa|up_7|NZ_CP023629.1_663373_664705_-	COG1926, COG1926, Predicted phosphoribosyltransferases [General function prediction only]	NA|114aa|up_6|NZ_CP023629.1_664928_665270_-	NA	NA|56aa|up_5|NZ_CP023629.1_665320_665488_-	NA	NA|464aa|up_4|NZ_CP023629.1_665737_667129_-	PRK12484, PRK12484, nicotinate phosphoribosyltransferase; Provisional	NA|381aa|up_3|NZ_CP023629.1_667138_668281_-	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]	NA|389aa|up_2|NZ_CP023629.1_668465_669632_-	PRK07588, PRK07588, FAD-binding domain	csa3|435aa|up_1|NZ_CP023629.1_669734_671039_+	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein	NA|262aa|up_0|NZ_CP023629.1_671052_671838_+	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only]	NA|253aa|down_0|NZ_CP023629.1_676124_676883_+	pfam01927, Mut7-C, Mut7-C RNAse domain	NA|164aa|down_1|NZ_CP023629.1_677011_677503_-	NA	NA|72aa|down_2|NZ_CP023629.1_677596_677812_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|down_3|NZ_CP023629.1_677808_678216_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|down_4|NZ_CP023629.1_678275_678962_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|down_5|NZ_CP023629.1_679115_681749_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|down_6|NZ_CP023629.1_681771_684159_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|down_7|NZ_CP023629.1_684296_685019_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|down_8|NZ_CP023629.1_685015_685813_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|down_9|NZ_CP023629.1_685814_686702_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	4	691912-691988	4	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023629.1_677596_677812_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023629.1_677808_678216_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023629.1_678275_678962_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023629.1_679115_681749_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023629.1_681771_684159_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023629.1_684296_685019_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023629.1_685015_685813_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023629.1_685814_686702_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023629.1_686707_687922_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023629.1_688945_690391_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023629.1_693123_694674_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023629.1_694725_695118_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023629.1_695114_695372_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023629.1_695554_696790_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023629.1_697040_697454_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023629.1_697450_697687_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023629.1_697790_698297_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023629.1_698410_698881_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023629.1_698924_699686_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023629.1_699742_700054_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	5	926486-927433	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927269-927304|927269-927304|927269-927304	NZ_CP023629.1_675015-674980|NZ_CP023629.1_1213624-1213659|NZ_CP023629.1_2423616-2423581	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023629.1_931443_931995_-,NA|81aa|down_8|NZ_CP023629.1_937458_937701_+	NA|685aa|up_9|NZ_CP023629.1_914122_916177_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023629.1_916342_917512_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023629.1_917599_918616_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023629.1_918777_919419_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023629.1_919499_920555_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023629.1_920606_920999_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023629.1_921056_921479_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023629.1_921440_921731_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023629.1_921835_922741_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023629.1_922759_923575_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023629.1_927702_930351_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023629.1_930818_931463_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023629.1_931443_931995_-	NA	NA|218aa|down_3|NZ_CP023629.1_932144_932798_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023629.1_932868_933897_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023629.1_934585_935356_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023629.1_935442_936255_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023629.1_936322_937183_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023629.1_937458_937701_+	NA	NA|431aa|down_9|NZ_CP023629.1_937977_939270_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	6	1191191-1191299	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023629.1_1180558_1182190_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023629.1_1182265_1183330_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023629.1_1183382_1183856_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023629.1_1183889_1184753_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023629.1_1184757_1185615_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023629.1_1185615_1186698_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023629.1_1186778_1187198_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023629.1_1187309_1187876_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023629.1_1187872_1188268_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023629.1_1188295_1190299_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023629.1_1192384_1194148_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023629.1_1194144_1194918_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023629.1_1194929_1195967_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023629.1_1196153_1196990_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023629.1_1197105_1197957_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023629.1_1198030_1199248_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023629.1_1199300_1200245_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023629.1_1200467_1201535_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023629.1_1201591_1202986_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023629.1_1203187_1203910_+	pfam06271, RDD, RDD family
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	7	1211825-1212681	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	73	1212208-1212229|1212253-1212268|1212391-1212412|1212391-1212412|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526|1212508-1212526	NZ_CP023629.1_2960391-2960370|NZ_CP023629.1_2088487-2088472|NZ_CP023629.1_837308-837329|NZ_CP023629.1_1217519-1217540|NZ_CP023629.1_674679-674661|NZ_CP023629.1_1213351-1213369|NZ_CP023629.1_1217492-1217510|NZ_CP023629.1_1217564-1217582|NZ_CP023629.1_1630576-1630558|NZ_CP023629.1_1633402-1633384|NZ_CP023629.1_1636797-1636779|NZ_CP023629.1_1990689-1990671|NZ_CP023629.1_2061415-2061397|NZ_CP023629.1_2061862-2061844|NZ_CP023629.1_2061961-2061943|NZ_CP023629.1_2801940-2801922|NZ_CP023629.1_2805468-2805450|NZ_CP023629.1_150189-150207|NZ_CP023629.1_333784-333766|NZ_CP023629.1_335203-335185|NZ_CP023629.1_335656-335638|NZ_CP023629.1_335707-335689|NZ_CP023629.1_335716-335698|NZ_CP023629.1_337987-337969|NZ_CP023629.1_338116-338098|NZ_CP023629.1_338383-338365|NZ_CP023629.1_338412-338430|NZ_CP023629.1_338506-338488|NZ_CP023629.1_363037-363019|NZ_CP023629.1_443336-443318|NZ_CP023629.1_546680-546662|NZ_CP023629.1_623870-623888|NZ_CP023629.1_624092-624110|NZ_CP023629.1_673845-673827|NZ_CP023629.1_840082-840100|NZ_CP023629.1_1090854-1090872|NZ_CP023629.1_1091502-1091520|NZ_CP023629.1_1095560-1095542|NZ_CP023629.1_1212880-1212898|NZ_CP023629.1_1213270-1213288|NZ_CP023629.1_1217912-1217930|NZ_CP023629.1_1618540-1618522|NZ_CP023629.1_1618993-1618975|NZ_CP023629.1_1635915-1635897|NZ_CP023629.1_1635924-1635906|NZ_CP023629.1_1864203-1864185|NZ_CP023629.1_1864731-1864713|NZ_CP023629.1_1989963-1989945|NZ_CP023629.1_2001327-2001345|NZ_CP023629.1_2088685-2088667|NZ_CP023629.1_2303388-2303370|NZ_CP023629.1_2356839-2356821|NZ_CP023629.1_2419442-2419460|NZ_CP023629.1_2423529-2423511|NZ_CP023629.1_2569023-2569005|NZ_CP023629.1_2693328-2693346|NZ_CP023629.1_2795255-2795237|NZ_CP023629.1_2795837-2795819|NZ_CP023629.1_3054427-3054445|NZ_CP023629.1_3054526-3054544|NZ_CP023629.1_3705342-3705360|NZ_CP023629.1_3737319-3737301|NZ_CP023629.1_3737943-3737925|NZ_CP023629.1_3738186-3738168|NZ_CP023629.1_3738319-3738301|NZ_CP023629.1_3802182-3802200|NZ_CP023629.1_3802365-3802383|NZ_CP023629.1_3802533-3802551|NZ_CP023629.1_3930346-3930364|NZ_CP023629.1_3932076-3932094|NZ_CP023629.1_3940583-3940601|NZ_CP023629.1_4031558-4031540|NZ_CP023629.1_4094083-4094101	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023629.1_1207257_1207524_+,NA|61aa|down_3|NZ_CP023629.1_1215099_1215282_+,NA|35aa|down_4|NZ_CP023629.1_1215391_1215496_+	NA|465aa|up_9|NZ_CP023629.1_1201591_1202986_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023629.1_1203187_1203910_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023629.1_1203941_1205108_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023629.1_1205178_1205673_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023629.1_1205858_1206293_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023629.1_1206394_1207261_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023629.1_1207257_1207524_+	NA	NA|674aa|up_2|NZ_CP023629.1_1207510_1209532_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023629.1_1209630_1210359_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023629.1_1210469_1211258_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023629.1_1213914_1214235_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023629.1_1214387_1214822_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP023629.1_1214920_1215088_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023629.1_1215099_1215282_+	NA	NA|35aa|down_4|NZ_CP023629.1_1215391_1215496_+	NA	NA|152aa|down_5|NZ_CP023629.1_1215473_1215929_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023629.1_1216343_1218905_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023629.1_1219122_1220061_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023629.1_1220448_1221729_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023629.1_1221833_1222661_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	8	1488969-1489088	1	PILER-CR	no	DinG	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type IV-A	AACCCGCCGGTGCCGCCGGCACCGCCGGCG	30	1	1	1488999-1489017	NZ_CP023629.1_399583-399601	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|99aa|up_3|NZ_CP023629.1_1484859_1485156_+,NA	NA|166aa|up_9|NZ_CP023629.1_1477011_1477509_-	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional	NA|497aa|up_8|NZ_CP023629.1_1477505_1478996_-	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]	NA|542aa|up_7|NZ_CP023629.1_1479076_1480702_-	cd07302, CHD, cyclase homology domain	NA|536aa|up_6|NZ_CP023629.1_1480771_1482379_-	cd07302, CHD, cyclase homology domain	NA|568aa|up_5|NZ_CP023629.1_1482391_1484095_-	COG2114, CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]	NA|224aa|up_4|NZ_CP023629.1_1484165_1484837_+	PRK03298, PRK03298, endonuclease NucS	NA|99aa|up_3|NZ_CP023629.1_1484859_1485156_+	NA	NA|153aa|up_2|NZ_CP023629.1_1485190_1485649_-	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE)	NA|394aa|up_1|NZ_CP023629.1_1485727_1486909_+	PRK05790, PRK05790, putative acyltransferase; Provisional	NA|305aa|up_0|NZ_CP023629.1_1487038_1487953_+	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]	NA|732aa|down_0|NZ_CP023629.1_1489994_1492190_-	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB	NA|702aa|down_1|NZ_CP023629.1_1492197_1494303_-	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins	NA|864aa|down_2|NZ_CP023629.1_1494441_1497033_+	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase	DinG|665aa|down_3|NZ_CP023629.1_1497072_1499067_-	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]	NA|449aa|down_4|NZ_CP023629.1_1499090_1500437_-	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated	NA|102aa|down_5|NZ_CP023629.1_1500538_1500844_+	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed	NA|219aa|down_6|NZ_CP023629.1_1500803_1501460_+	pfam09438, DUF2017, Domain of unknown function (DUF2017)	NA|345aa|down_7|NZ_CP023629.1_1501476_1502511_+	COG3191, DmpA, L-aminopeptidase/D-esterase [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|147aa|down_8|NZ_CP023629.1_1502518_1502959_+	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding)	NA|94aa|down_9|NZ_CP023629.1_1502980_1503262_+	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	9	1572064-1573135	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP023629.1_1563827_1564145_+,NA	NA|103aa|up_9|NZ_CP023629.1_1561342_1561651_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023629.1_1561647_1563267_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023629.1_1563827_1564145_+	NA	NA|209aa|up_6|NZ_CP023629.1_1564279_1564906_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023629.1_1564971_1565304_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023629.1_1565319_1566576_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023629.1_1566703_1567915_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023629.1_1567987_1569466_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023629.1_1569462_1570848_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023629.1_1570925_1571960_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023629.1_1573989_1574391_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023629.1_1574387_1574645_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023629.1_1574727_1575687_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023629.1_1575711_1576674_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023629.1_1576807_1577410_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023629.1_1577490_1579458_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023629.1_1579475_1580300_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023629.1_1580468_1580951_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023629.1_1581022_1581847_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023629.1_1582043_1582982_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	10	1636493-1636719	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP023629.1_1623001_1623115_-,NA|137aa|up_7|NZ_CP023629.1_1623164_1623575_-,NA|288aa|down_2|NZ_CP023629.1_1640557_1641421_+	NA|162aa|up_9|NZ_CP023629.1_1622084_1622570_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP023629.1_1623001_1623115_-	NA	NA|137aa|up_7|NZ_CP023629.1_1623164_1623575_-	NA	NA|248aa|up_6|NZ_CP023629.1_1623591_1624335_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP023629.1_1624331_1625243_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP023629.1_1625295_1626840_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP023629.1_1626836_1627958_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP023629.1_1627974_1630077_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP023629.1_1630515_1634505_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP023629.1_1634906_1635833_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP023629.1_1638258_1639524_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP023629.1_1639551_1640538_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP023629.1_1640557_1641421_+	NA	NA|311aa|down_3|NZ_CP023629.1_1641370_1642303_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP023629.1_1642414_1643200_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP023629.1_1643196_1644138_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP023629.1_1644240_1646016_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP023629.1_1646063_1646870_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP023629.1_1646866_1649407_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP023629.1_1649403_1650597_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	11	2088157-2088411	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088238-2088255|2088238-2088255|2088328-2088345	NZ_CP023629.1_401062-401045|NZ_CP023629.1_607325-607308|NZ_CP023629.1_3450043-3450026	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023629.1_2087516_2087780_-,NA	NA|165aa|up_9|NZ_CP023629.1_2073810_2074305_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023629.1_2074708_2075386_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023629.1_2075744_2078570_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023629.1_2078796_2079657_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023629.1_2079697_2080564_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023629.1_2080568_2082455_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023629.1_2082470_2084504_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023629.1_2084623_2086849_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023629.1_2087124_2087520_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023629.1_2087516_2087780_-	NA	NA|346aa|down_0|NZ_CP023629.1_2089548_2090586_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023629.1_2090585_2091953_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023629.1_2092126_2093563_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023629.1_2093598_2095050_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023629.1_2095079_2096030_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023629.1_2096044_2096461_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023629.1_2096738_2097161_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023629.1_2097209_2097512_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023629.1_2097508_2097823_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023629.1_2097822_2099556_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	12	2163249-2163353	8	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023629.1_2159793_2160201_-,NA|127aa|down_6|NZ_CP023629.1_2176422_2176803_-	NA|216aa|up_9|NZ_CP023629.1_2153107_2153755_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023629.1_2153761_2155984_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023629.1_2156021_2156465_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023629.1_2156578_2157172_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023629.1_2157254_2157860_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023629.1_2157959_2158964_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023629.1_2159063_2159816_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023629.1_2159793_2160201_-	NA	NA|368aa|up_1|NZ_CP023629.1_2160335_2161439_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023629.1_2161438_2162635_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023629.1_2167521_2170485_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023629.1_2170933_2171398_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023629.1_2171495_2172359_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023629.1_2172396_2173668_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023629.1_2173939_2175055_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023629.1_2175045_2176386_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023629.1_2176422_2176803_-	NA	NA|621aa|down_7|NZ_CP023629.1_2176959_2178822_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023629.1_2178829_2179309_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023629.1_2179545_2180319_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	13	2168687-2168906	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP023629.1_2159793_2160201_-,NA|127aa|down_5|NZ_CP023629.1_2176422_2176803_-	NA|741aa|up_9|NZ_CP023629.1_2153761_2155984_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023629.1_2156021_2156465_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023629.1_2156578_2157172_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023629.1_2157254_2157860_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023629.1_2157959_2158964_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023629.1_2159063_2159816_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023629.1_2159793_2160201_-	NA	NA|368aa|up_2|NZ_CP023629.1_2160335_2161439_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023629.1_2161438_2162635_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023629.1_2162804_2167184_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023629.1_2170933_2171398_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023629.1_2171495_2172359_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023629.1_2172396_2173668_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023629.1_2173939_2175055_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023629.1_2175045_2176386_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023629.1_2176422_2176803_-	NA	NA|621aa|down_6|NZ_CP023629.1_2176959_2178822_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023629.1_2178829_2179309_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023629.1_2179545_2180319_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023629.1_2180322_2181090_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	14	3119018-3120372	3,10,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-C,Type III-A,Type III-D	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-B,TypeIII-C,TypeIII-A,TypeIII-D	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023629.1_3112297_3112552_-,NA|135aa|up_7|NZ_CP023629.1_3112699_3113104_+,NA|64aa|up_6|NZ_CP023629.1_3113100_3113292_+,NA|86aa|up_4|NZ_CP023629.1_3114878_3115136_+,NA|104aa|up_3|NZ_CP023629.1_3115240_3115552_+,NA|203aa|up_2|NZ_CP023629.1_3115971_3116580_+,NA	NA|92aa|up_9|NZ_CP023629.1_3111846_3112122_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023629.1_3112297_3112552_-	NA	NA|135aa|up_7|NZ_CP023629.1_3112699_3113104_+	NA	NA|64aa|up_6|NZ_CP023629.1_3113100_3113292_+	NA	NA|385aa|up_5|NZ_CP023629.1_3113490_3114645_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023629.1_3114878_3115136_+	NA	NA|104aa|up_3|NZ_CP023629.1_3115240_3115552_+	NA	NA|203aa|up_2|NZ_CP023629.1_3115971_3116580_+	NA	NA|470aa|up_1|NZ_CP023629.1_3116650_3118060_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023629.1_3118056_3118869_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023629.1_3120398_3121660_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023629.1_3123457_3123799_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023629.1_3123799_3124816_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023629.1_3124828_3125977_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023629.1_3126072_3127200_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023629.1_3127196_3128105_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023629.1_3128085_3128796_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023629.1_3128805_3129180_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023629.1_3129176_3131615_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023629.1_3131611_3132334_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	15	3121695-3123409	11,4,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-C,Type III-A,Type III-D	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-B,TypeIII-C,TypeIII-A,TypeIII-D	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023629.1_3112297_3112552_-,NA|135aa|up_8|NZ_CP023629.1_3112699_3113104_+,NA|64aa|up_7|NZ_CP023629.1_3113100_3113292_+,NA|86aa|up_5|NZ_CP023629.1_3114878_3115136_+,NA|104aa|up_4|NZ_CP023629.1_3115240_3115552_+,NA|203aa|up_3|NZ_CP023629.1_3115971_3116580_+,NA	NA|85aa|up_9|NZ_CP023629.1_3112297_3112552_-	NA	NA|135aa|up_8|NZ_CP023629.1_3112699_3113104_+	NA	NA|64aa|up_7|NZ_CP023629.1_3113100_3113292_+	NA	NA|385aa|up_6|NZ_CP023629.1_3113490_3114645_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023629.1_3114878_3115136_+	NA	NA|104aa|up_4|NZ_CP023629.1_3115240_3115552_+	NA	NA|203aa|up_3|NZ_CP023629.1_3115971_3116580_+	NA	NA|470aa|up_2|NZ_CP023629.1_3116650_3118060_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023629.1_3118056_3118869_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023629.1_3120398_3121660_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023629.1_3123457_3123799_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023629.1_3123799_3124816_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023629.1_3124828_3125977_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023629.1_3126072_3127200_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023629.1_3127196_3128105_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023629.1_3128085_3128796_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023629.1_3128805_3129180_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023629.1_3129176_3131615_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023629.1_3131611_3132334_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023629.1_3132733_3133279_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	16	3740513-3741054	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023629.1_3755155_3755443_-,NA|87aa|down_9|NZ_CP023629.1_3768563_3768824_-	NA|282aa|up_9|NZ_CP023629.1_3719764_3720610_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023629.1_3721084_3721525_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023629.1_3721558_3722428_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023629.1_3722448_3723459_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023629.1_3723743_3724376_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023629.1_3724442_3725672_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023629.1_3725954_3727304_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023629.1_3727315_3728455_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023629.1_3728451_3729183_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023629.1_3729191_3736763_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023629.1_3743025_3743283_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023629.1_3743538_3753012_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023629.1_3753637_3754084_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023629.1_3754120_3754861_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023629.1_3755155_3755443_-	NA	NA|3717aa|down_5|NZ_CP023629.1_3755779_3766930_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023629.1_3767173_3767968_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023629.1_3768049_3768421_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023629.1_3768318_3768537_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023629.1_3768563_3768824_-	NA
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	17	3948191-3949942	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCNNCGGCGGNNNCGGCGG	36	2	9	3948782-3948817|3948782-3948817|3948782-3948817|3948782-3948817|3948782-3948817|3949673-3949699|3949673-3949699|3949673-3949699|3949673-3949699	NZ_CP023629.1_3946898-3946933|NZ_CP023629.1_3947240-3947275|NZ_CP023629.1_3947831-3947866|NZ_CP023629.1_3948182-3948217|NZ_CP023629.1_3932631-3932666|NZ_CP023629.1_361977-362003|NZ_CP023629.1_3941084-3941110|NZ_CP023629.1_3941420-3941446|NZ_CP023629.1_3941766-3941792	NA	21	21	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP023629.1_3953257_3954097_+	NA|318aa|up_9|NZ_CP023629.1_3920913_3921867_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP023629.1_3921891_3922083_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP023629.1_3922297_3923500_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP023629.1_3923524_3924646_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP023629.1_3924716_3926225_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1382aa|up_4|NZ_CP023629.1_3926395_3930541_+	pfam00934, PE, PE family	NA|1902aa|up_3|NZ_CP023629.1_3930831_3936537_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP023629.1_3936703_3938251_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP023629.1_3938247_3939084_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP023629.1_3944918_3945575_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023629.1_3950650_3952297_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023629.1_3952370_3953162_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023629.1_3953257_3954097_+	NA	NA|399aa|down_3|NZ_CP023629.1_3954151_3955348_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023629.1_3955376_3956087_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023629.1_3956151_3957195_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023629.1_3957347_3958259_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023629.1_3958274_3959339_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023629.1_3959355_3960540_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023629.1_3960581_3961613_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002447995.1_ASM244799v1	NZ_CP023629	Mycobacterium tuberculosis strain MDRMA2260 chromosome, complete genome	18	4110500-4110588	12	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023629.1_4101086_4101857_-,NA|119aa|up_3|NZ_CP023629.1_4106991_4107348_+,NA|52aa|up_2|NZ_CP023629.1_4107447_4107603_+,NA|233aa|up_0|NZ_CP023629.1_4109604_4110303_-,NA|126aa|down_6|NZ_CP023629.1_4115823_4116201_+	NA|288aa|up_9|NZ_CP023629.1_4099468_4100332_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023629.1_4101086_4101857_-	NA	NA|549aa|up_7|NZ_CP023629.1_4101853_4103500_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023629.1_4103496_4104360_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023629.1_4104352_4105279_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023629.1_4105280_4106906_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023629.1_4106991_4107348_+	NA	NA|52aa|up_2|NZ_CP023629.1_4107447_4107603_+	NA	NA|652aa|up_1|NZ_CP023629.1_4107613_4109569_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023629.1_4109604_4110303_-	NA	NA|173aa|down_0|NZ_CP023629.1_4110648_4111167_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023629.1_4111167_4112151_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023629.1_4112143_4113337_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023629.1_4113342_4114164_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023629.1_4114295_4114979_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023629.1_4114978_4115716_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023629.1_4115823_4116201_+	NA	NA|225aa|down_7|NZ_CP023629.1_4116299_4116974_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023629.1_4117079_4117874_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023629.1_4117880_4118336_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
