assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	1	333667-334386	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGGCGCCGCCGGNG	18	0	0	NA	NA	NA	14	14	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|61aa|up_0|NZ_CP023627.1_333106_333289_-,NA	NA|398aa|up_9|NZ_CP023627.1_323284_324478_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP023627.1_324513_326196_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP023627.1_326212_328408_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP023627.1_328521_329655_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP023627.1_329651_330272_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP023627.1_330368_330950_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP023627.1_330879_331605_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP023627.1_331694_332615_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP023627.1_332654_333083_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP023627.1_333106_333289_-	NA	NA|838aa|down_0|NZ_CP023627.1_336485_338999_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP023627.1_339289_340900_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP023627.1_340923_341832_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP023627.1_342055_343951_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP023627.1_343947_345564_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP023627.1_345560_349553_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP023627.1_349549_349858_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP023627.1_349860_351402_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP023627.1_351450_351744_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP023627.1_351773_352064_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	2	337586-338005	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CGCCGNCGGNNCCGNCGG	18	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|61aa|up_1|NZ_CP023627.1_333106_333289_-,NA	NA|561aa|up_9|NZ_CP023627.1_324513_326196_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP023627.1_326212_328408_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP023627.1_328521_329655_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP023627.1_329651_330272_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP023627.1_330368_330950_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP023627.1_330879_331605_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP023627.1_331694_332615_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP023627.1_332654_333083_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP023627.1_333106_333289_-	NA	NA|614aa|up_0|NZ_CP023627.1_333383_335225_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|537aa|down_0|NZ_CP023627.1_339289_340900_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP023627.1_340923_341832_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP023627.1_342055_343951_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP023627.1_343947_345564_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP023627.1_345560_349553_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP023627.1_349549_349858_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP023627.1_349860_351402_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP023627.1_351450_351744_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP023627.1_351773_352064_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP023627.1_352074_352962_+	pfam14011, ESX-1_EspG, EspG family
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	3	338030-338252	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|61aa|up_1|NZ_CP023627.1_333106_333289_-,NA	NA|561aa|up_9|NZ_CP023627.1_324513_326196_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP023627.1_326212_328408_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP023627.1_328521_329655_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP023627.1_329651_330272_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP023627.1_330368_330950_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP023627.1_330879_331605_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP023627.1_331694_332615_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP023627.1_332654_333083_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP023627.1_333106_333289_-	NA	NA|614aa|up_0|NZ_CP023627.1_333383_335225_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|537aa|down_0|NZ_CP023627.1_339289_340900_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP023627.1_340923_341832_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP023627.1_342055_343951_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP023627.1_343947_345564_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP023627.1_345560_349553_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP023627.1_349549_349858_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP023627.1_349860_351402_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP023627.1_351450_351744_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP023627.1_351773_352064_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP023627.1_352074_352962_+	pfam14011, ESX-1_EspG, EspG family
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	4	366389-367087	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366677-366718|366752-366784	NZ_CP023627.1_374708-374749|NZ_CP023627.1_373523-373555	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|101aa|up_4|NZ_CP023627.1_363401_363704_+,NA|161aa|down_1|NZ_CP023627.1_376497_376980_-,NA|410aa|down_5|NZ_CP023627.1_379096_380326_+	NA|262aa|up_9|NZ_CP023627.1_358096_358882_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023627.1_358870_359674_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023627.1_359683_361081_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023627.1_361259_363035_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023627.1_363177_363405_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023627.1_363401_363704_+	NA	NA|74aa|up_3|NZ_CP023627.1_363751_363973_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023627.1_363969_364395_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023627.1_364530_365163_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023627.1_365159_366068_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023627.1_375838_376510_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023627.1_376497_376980_-	NA	NA|239aa|down_2|NZ_CP023627.1_377037_377754_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023627.1_377855_378512_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023627.1_378581_379073_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023627.1_379096_380326_+	NA	NA|621aa|down_6|NZ_CP023627.1_380480_382343_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023627.1_382414_382801_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023627.1_382803_383466_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023627.1_383526_384411_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	5	691845-691921	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|136aa|up_9|NZ_CP023627.1_677740_678148_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP023627.1_678207_678894_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP023627.1_679047_681681_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP023627.1_681703_684091_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP023627.1_684228_684951_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP023627.1_684947_685745_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP023627.1_685746_686634_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP023627.1_686639_687854_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_1|NZ_CP023627.1_688877_690323_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|479aa|up_0|NZ_CP023627.1_690319_691756_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023627.1_693056_694607_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023627.1_694658_695051_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023627.1_695047_695305_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023627.1_695487_696723_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023627.1_696973_697387_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023627.1_697383_697620_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023627.1_697723_698230_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023627.1_698343_698814_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023627.1_698857_699619_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023627.1_699675_699987_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	6	926441-927379	3	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927224-927259|927224-927259|927224-927259	NZ_CP023627.1_674947-674912|NZ_CP023627.1_1213555-1213590|NZ_CP023627.1_2423521-2423486	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|184aa|down_2|NZ_CP023627.1_931389_931941_-,NA|81aa|down_8|NZ_CP023627.1_937404_937647_+	NA|685aa|up_9|NZ_CP023627.1_914077_916132_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023627.1_916297_917467_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023627.1_917554_918571_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023627.1_918732_919374_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023627.1_919454_920510_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023627.1_920561_920954_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023627.1_921011_921434_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023627.1_921395_921686_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023627.1_921790_922696_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023627.1_922714_923530_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023627.1_927648_930297_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023627.1_930764_931409_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023627.1_931389_931941_-	NA	NA|218aa|down_3|NZ_CP023627.1_932090_932744_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023627.1_932814_933843_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023627.1_934531_935302_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023627.1_935388_936201_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023627.1_936268_937129_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023627.1_937404_937647_+	NA	NA|431aa|down_9|NZ_CP023627.1_937923_939216_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	7	964393-964644	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGT	63	1	1	964566-964621	NZ_CP023627.1_964694-964749	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|67aa|up_3|NZ_CP023627.1_962491_962692_+,NA	NA|158aa|up_9|NZ_CP023627.1_953068_953542_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|398aa|up_8|NZ_CP023627.1_953538_954732_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|404aa|up_7|NZ_CP023627.1_954888_956100_+	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase	NA|721aa|up_6|NZ_CP023627.1_956104_958267_+	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB	NA|543aa|up_5|NZ_CP023627.1_958334_959963_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|757aa|up_4|NZ_CP023627.1_960153_962424_-	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|67aa|up_3|NZ_CP023627.1_962491_962692_+	NA	NA|168aa|up_2|NZ_CP023627.1_962701_963205_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|161aa|up_1|NZ_CP023627.1_963201_963684_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|142aa|up_0|NZ_CP023627.1_963680_964106_+	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism]	NA|93aa|down_0|NZ_CP023627.1_965794_966073_-	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins	NA|361aa|down_1|NZ_CP023627.1_966076_967159_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|130aa|down_2|NZ_CP023627.1_967155_967545_-	PRK11770, PRK11770, YccF domain-containing protein	NA|136aa|down_3|NZ_CP023627.1_967709_968117_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|610aa|down_4|NZ_CP023627.1_968235_970065_-	pfam00934, PE, PE family	NA|651aa|down_5|NZ_CP023627.1_970325_972278_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|387aa|down_6|NZ_CP023627.1_972366_973527_-	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|163aa|down_7|NZ_CP023627.1_973626_974115_-	pfam10969, DUF2771, Protein of unknown function (DUF2771)	NA|549aa|down_8|NZ_CP023627.1_974111_975758_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|263aa|down_9|NZ_CP023627.1_975895_976684_+	pfam11228, DUF3027, Protein of unknown function (DUF3027)
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	8	1191122-1191230	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|544aa|up_9|NZ_CP023627.1_1180498_1182130_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023627.1_1182205_1183270_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023627.1_1183322_1183796_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023627.1_1183829_1184693_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023627.1_1184697_1185555_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023627.1_1185555_1186638_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023627.1_1186718_1187138_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023627.1_1187249_1187816_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023627.1_1187812_1188208_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023627.1_1188235_1190239_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023627.1_1192315_1194079_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023627.1_1194075_1194849_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023627.1_1194860_1195898_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023627.1_1196084_1196921_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023627.1_1197036_1197888_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023627.1_1197961_1199179_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023627.1_1199231_1200176_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023627.1_1200398_1201466_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023627.1_1201522_1202917_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023627.1_1203118_1203841_+	pfam06271, RDD, RDD family
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	9	1211756-1212612	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	69	1212139-1212160|1212184-1212199|1212322-1212343|1212322-1212343|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457|1212439-1212457	NZ_CP023627.1_2960286-2960265|NZ_CP023627.1_2088410-2088395|NZ_CP023627.1_837253-837274|NZ_CP023627.1_1217450-1217471|NZ_CP023627.1_674611-674593|NZ_CP023627.1_1213282-1213300|NZ_CP023627.1_1217423-1217441|NZ_CP023627.1_1217495-1217513|NZ_CP023627.1_1630500-1630482|NZ_CP023627.1_1633326-1633308|NZ_CP023627.1_1990613-1990595|NZ_CP023627.1_2061338-2061320|NZ_CP023627.1_2061785-2061767|NZ_CP023627.1_2061884-2061866|NZ_CP023627.1_2801835-2801817|NZ_CP023627.1_2805363-2805345|NZ_CP023627.1_150188-150206|NZ_CP023627.1_335145-335127|NZ_CP023627.1_335598-335580|NZ_CP023627.1_335649-335631|NZ_CP023627.1_335658-335640|NZ_CP023627.1_338325-338307|NZ_CP023627.1_338354-338372|NZ_CP023627.1_338448-338430|NZ_CP023627.1_362979-362961|NZ_CP023627.1_443281-443263|NZ_CP023627.1_546612-546594|NZ_CP023627.1_623802-623820|NZ_CP023627.1_624024-624042|NZ_CP023627.1_673777-673759|NZ_CP023627.1_840036-840054|NZ_CP023627.1_1090798-1090816|NZ_CP023627.1_1091446-1091464|NZ_CP023627.1_1095504-1095486|NZ_CP023627.1_1212811-1212829|NZ_CP023627.1_1213201-1213219|NZ_CP023627.1_1217843-1217861|NZ_CP023627.1_1489020-1489002|NZ_CP023627.1_1618917-1618899|NZ_CP023627.1_1635839-1635821|NZ_CP023627.1_1635848-1635830|NZ_CP023627.1_1864127-1864109|NZ_CP023627.1_1864655-1864637|NZ_CP023627.1_1989887-1989869|NZ_CP023627.1_2001250-2001268|NZ_CP023627.1_2088608-2088590|NZ_CP023627.1_2303299-2303281|NZ_CP023627.1_2356751-2356733|NZ_CP023627.1_2419347-2419365|NZ_CP023627.1_2423434-2423416|NZ_CP023627.1_2568927-2568909|NZ_CP023627.1_2693226-2693244|NZ_CP023627.1_2795150-2795132|NZ_CP023627.1_2795732-2795714|NZ_CP023627.1_3054321-3054339|NZ_CP023627.1_3054420-3054438|NZ_CP023627.1_3705235-3705253|NZ_CP023627.1_3737212-3737194|NZ_CP023627.1_3737836-3737818|NZ_CP023627.1_3738079-3738061|NZ_CP023627.1_3738212-3738194|NZ_CP023627.1_3802051-3802069|NZ_CP023627.1_3802234-3802252|NZ_CP023627.1_3802402-3802420|NZ_CP023627.1_3930222-3930240|NZ_CP023627.1_3931952-3931970|NZ_CP023627.1_3940459-3940477|NZ_CP023627.1_4031451-4031433|NZ_CP023627.1_4093973-4093991	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|89aa|up_3|NZ_CP023627.1_1207188_1207455_+,NA|61aa|down_3|NZ_CP023627.1_1215030_1215213_+,NA|35aa|down_4|NZ_CP023627.1_1215322_1215427_+	NA|465aa|up_9|NZ_CP023627.1_1201522_1202917_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023627.1_1203118_1203841_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023627.1_1203872_1205039_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023627.1_1205109_1205604_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023627.1_1205789_1206224_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023627.1_1206325_1207192_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023627.1_1207188_1207455_+	NA	NA|674aa|up_2|NZ_CP023627.1_1207441_1209463_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023627.1_1209561_1210290_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023627.1_1210400_1211189_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023627.1_1213845_1214166_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023627.1_1214318_1214753_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP023627.1_1214851_1215019_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023627.1_1215030_1215213_+	NA	NA|35aa|down_4|NZ_CP023627.1_1215322_1215427_+	NA	NA|152aa|down_5|NZ_CP023627.1_1215404_1215860_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023627.1_1216274_1218836_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023627.1_1219053_1219992_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023627.1_1220379_1221660_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023627.1_1221763_1222591_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	10	1571987-1573059	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|106aa|up_7|NZ_CP023627.1_1563750_1564068_+,NA	NA|103aa|up_9|NZ_CP023627.1_1561265_1561574_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023627.1_1561570_1563190_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023627.1_1563750_1564068_+	NA	NA|209aa|up_6|NZ_CP023627.1_1564202_1564829_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023627.1_1564894_1565227_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023627.1_1565242_1566499_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023627.1_1566626_1567838_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023627.1_1567910_1569389_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023627.1_1569385_1570771_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023627.1_1570848_1571883_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023627.1_1573913_1574315_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023627.1_1574311_1574569_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023627.1_1574651_1575611_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023627.1_1575635_1576598_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023627.1_1576731_1577334_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023627.1_1577414_1579382_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023627.1_1579399_1580224_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023627.1_1580392_1580875_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023627.1_1580946_1581771_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023627.1_1581967_1582906_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	11	2088080-2088334	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088161-2088178|2088161-2088178|2088251-2088268	NZ_CP023627.1_401004-400987|NZ_CP023627.1_607257-607240|NZ_CP023627.1_3449936-3449919	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|88aa|up_0|NZ_CP023627.1_2087439_2087703_-,NA	NA|165aa|up_9|NZ_CP023627.1_2073733_2074228_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023627.1_2074631_2075309_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023627.1_2075667_2078493_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023627.1_2078719_2079580_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023627.1_2079620_2080487_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023627.1_2080491_2082378_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023627.1_2082393_2084427_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023627.1_2084546_2086772_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023627.1_2087047_2087443_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023627.1_2087439_2087703_-	NA	NA|346aa|down_0|NZ_CP023627.1_2089462_2090500_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023627.1_2090499_2091867_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023627.1_2092040_2093477_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023627.1_2093512_2094964_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023627.1_2094993_2095944_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023627.1_2095958_2096375_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023627.1_2096652_2097075_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023627.1_2097123_2097426_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023627.1_2097422_2097737_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023627.1_2097736_2099470_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	12	2163163-2163267	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|136aa|up_2|NZ_CP023627.1_2159707_2160115_-,NA|127aa|down_6|NZ_CP023627.1_2176336_2176717_-	NA|216aa|up_9|NZ_CP023627.1_2153021_2153669_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023627.1_2153675_2155898_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023627.1_2155935_2156379_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023627.1_2156492_2157086_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023627.1_2157168_2157774_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023627.1_2157873_2158878_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023627.1_2158977_2159730_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023627.1_2159707_2160115_-	NA	NA|368aa|up_1|NZ_CP023627.1_2160249_2161353_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023627.1_2161352_2162549_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023627.1_2167435_2170399_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023627.1_2170847_2171312_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023627.1_2171409_2172273_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023627.1_2172310_2173582_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023627.1_2173853_2174969_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023627.1_2174959_2176300_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023627.1_2176336_2176717_-	NA	NA|621aa|down_7|NZ_CP023627.1_2176873_2178736_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023627.1_2178743_2179223_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023627.1_2179459_2180233_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	13	2168601-2168820	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|136aa|up_3|NZ_CP023627.1_2159707_2160115_-,NA|127aa|down_5|NZ_CP023627.1_2176336_2176717_-	NA|741aa|up_9|NZ_CP023627.1_2153675_2155898_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023627.1_2155935_2156379_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023627.1_2156492_2157086_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023627.1_2157168_2157774_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023627.1_2157873_2158878_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023627.1_2158977_2159730_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023627.1_2159707_2160115_-	NA	NA|368aa|up_2|NZ_CP023627.1_2160249_2161353_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023627.1_2161352_2162549_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023627.1_2162718_2167098_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023627.1_2170847_2171312_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023627.1_2171409_2172273_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023627.1_2172310_2173582_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023627.1_2173853_2174969_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023627.1_2174959_2176300_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023627.1_2176336_2176717_-	NA	NA|621aa|down_6|NZ_CP023627.1_2176873_2178736_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023627.1_2178743_2179223_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023627.1_2179459_2180233_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023627.1_2180236_2181004_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	14	3118912-3120266	3,8,5	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type III-C,Type III-A,Type III-B,Type III-D	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-C,TypeIII-A,TypeIII-B,TypeIII-D	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|85aa|up_8|NZ_CP023627.1_3112191_3112446_-,NA|135aa|up_7|NZ_CP023627.1_3112593_3112998_+,NA|64aa|up_6|NZ_CP023627.1_3112994_3113186_+,NA|86aa|up_4|NZ_CP023627.1_3114772_3115030_+,NA|104aa|up_3|NZ_CP023627.1_3115134_3115446_+,NA|203aa|up_2|NZ_CP023627.1_3115865_3116474_+,NA	NA|92aa|up_9|NZ_CP023627.1_3111740_3112016_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023627.1_3112191_3112446_-	NA	NA|135aa|up_7|NZ_CP023627.1_3112593_3112998_+	NA	NA|64aa|up_6|NZ_CP023627.1_3112994_3113186_+	NA	NA|385aa|up_5|NZ_CP023627.1_3113384_3114539_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023627.1_3114772_3115030_+	NA	NA|104aa|up_3|NZ_CP023627.1_3115134_3115446_+	NA	NA|203aa|up_2|NZ_CP023627.1_3115865_3116474_+	NA	NA|470aa|up_1|NZ_CP023627.1_3116544_3117954_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023627.1_3117950_3118763_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023627.1_3120292_3121554_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023627.1_3123351_3123693_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023627.1_3123693_3124710_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023627.1_3124722_3125871_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023627.1_3125966_3127094_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023627.1_3127090_3127999_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023627.1_3127979_3128690_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023627.1_3128699_3129074_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023627.1_3129070_3131509_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023627.1_3131505_3132228_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	15	3121589-3123303	9,6,4,5	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type III-C,Type III-A,Type III-B,Type III-D	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A:II-B,III-A	23,23,20,20	23	TypeIII-C,TypeIII-A,TypeIII-B,TypeIII-D	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|85aa|up_9|NZ_CP023627.1_3112191_3112446_-,NA|135aa|up_8|NZ_CP023627.1_3112593_3112998_+,NA|64aa|up_7|NZ_CP023627.1_3112994_3113186_+,NA|86aa|up_5|NZ_CP023627.1_3114772_3115030_+,NA|104aa|up_4|NZ_CP023627.1_3115134_3115446_+,NA|203aa|up_3|NZ_CP023627.1_3115865_3116474_+,NA	NA|85aa|up_9|NZ_CP023627.1_3112191_3112446_-	NA	NA|135aa|up_8|NZ_CP023627.1_3112593_3112998_+	NA	NA|64aa|up_7|NZ_CP023627.1_3112994_3113186_+	NA	NA|385aa|up_6|NZ_CP023627.1_3113384_3114539_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023627.1_3114772_3115030_+	NA	NA|104aa|up_4|NZ_CP023627.1_3115134_3115446_+	NA	NA|203aa|up_3|NZ_CP023627.1_3115865_3116474_+	NA	NA|470aa|up_2|NZ_CP023627.1_3116544_3117954_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023627.1_3117950_3118763_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023627.1_3120292_3121554_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023627.1_3123351_3123693_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023627.1_3123693_3124710_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023627.1_3124722_3125871_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023627.1_3125966_3127094_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023627.1_3127090_3127999_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023627.1_3127979_3128690_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023627.1_3128699_3129074_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023627.1_3129070_3131509_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023627.1_3131505_3132228_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023627.1_3132627_3133173_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	16	3740382-3740923	7	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|96aa|down_4|NZ_CP023627.1_3755024_3755312_-,NA|87aa|down_9|NZ_CP023627.1_3768432_3768693_-	NA|282aa|up_9|NZ_CP023627.1_3719657_3720503_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023627.1_3720977_3721418_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023627.1_3721451_3722321_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023627.1_3722341_3723352_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023627.1_3723636_3724269_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023627.1_3724335_3725565_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023627.1_3725847_3727197_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023627.1_3727208_3728348_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023627.1_3728344_3729076_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023627.1_3729084_3736656_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023627.1_3742894_3743152_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023627.1_3743407_3752881_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023627.1_3753506_3753953_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023627.1_3753989_3754730_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023627.1_3755024_3755312_-	NA	NA|3717aa|down_5|NZ_CP023627.1_3755648_3766799_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023627.1_3767042_3767837_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023627.1_3767918_3768290_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023627.1_3768187_3768406_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023627.1_3768432_3768693_-	NA
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	17	3947607-3949682	8	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CNNCGGCGGNNCCGNCGGCANCGGCGGCNNCGGCGG	36	3	6	3947778-3947873|3947910-3947984|3947910-3947984|3948675-3948710|3948675-3948710|3948675-3948710	NZ_CP023627.1_3947187-3947282|NZ_CP023627.1_3946968-3947042|NZ_CP023627.1_3947319-3947393|NZ_CP023627.1_3946782-3946817|NZ_CP023627.1_3947124-3947159|NZ_CP023627.1_3932507-3932542	NA	22	22	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|280aa|down_2|NZ_CP023627.1_3953150_3953990_+	NA|64aa|up_9|NZ_CP023627.1_3921758_3921950_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_8|NZ_CP023627.1_3922164_3923367_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_7|NZ_CP023627.1_3923391_3924513_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_6|NZ_CP023627.1_3924583_3926092_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1385aa|up_5|NZ_CP023627.1_3926262_3930417_+	pfam00934, PE, PE family	NA|1902aa|up_4|NZ_CP023627.1_3930707_3936413_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP023627.1_3936579_3938127_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP023627.1_3938123_3938960_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1782aa|up_1|NZ_CP023627.1_3939319_3944665_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP023627.1_3944793_3945450_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023627.1_3950543_3952190_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023627.1_3952263_3953055_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023627.1_3953150_3953990_+	NA	NA|399aa|down_3|NZ_CP023627.1_3954044_3955241_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023627.1_3955269_3955980_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023627.1_3956044_3957088_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023627.1_3957240_3958152_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023627.1_3958167_3959232_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023627.1_3959248_3960433_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023627.1_3960474_3961506_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002447955.1_ASM244795v1	NZ_CP023627	Mycobacterium tuberculosis strain MDRMA2019 chromosome, complete genome	18	4110390-4110478	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|257aa|up_8|NZ_CP023627.1_4100976_4101747_-,NA|119aa|up_3|NZ_CP023627.1_4106881_4107238_+,NA|52aa|up_2|NZ_CP023627.1_4107337_4107493_+,NA|233aa|up_0|NZ_CP023627.1_4109494_4110193_-,NA|126aa|down_6|NZ_CP023627.1_4115713_4116091_+	NA|288aa|up_9|NZ_CP023627.1_4099358_4100222_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023627.1_4100976_4101747_-	NA	NA|549aa|up_7|NZ_CP023627.1_4101743_4103390_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023627.1_4103386_4104250_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023627.1_4104242_4105169_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023627.1_4105170_4106796_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023627.1_4106881_4107238_+	NA	NA|52aa|up_2|NZ_CP023627.1_4107337_4107493_+	NA	NA|652aa|up_1|NZ_CP023627.1_4107503_4109459_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023627.1_4109494_4110193_-	NA	NA|173aa|down_0|NZ_CP023627.1_4110538_4111057_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023627.1_4111057_4112041_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023627.1_4112033_4113227_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023627.1_4113232_4114054_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023627.1_4114185_4114869_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023627.1_4114868_4115606_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023627.1_4115713_4116091_+	NA	NA|225aa|down_7|NZ_CP023627.1_4116189_4116864_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023627.1_4116969_4117764_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023627.1_4117770_4118226_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
