assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	1	333555-334353	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGNGCCGCCGGNN	18	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP023607.1_333070_333253_-,NA	NA|398aa|up_9|NZ_CP023607.1_323248_324442_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP023607.1_324477_326160_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP023607.1_326176_328372_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP023607.1_328485_329619_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP023607.1_329615_330236_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP023607.1_330332_330914_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP023607.1_330843_331569_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP023607.1_331658_332579_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP023607.1_332618_333047_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP023607.1_333070_333253_-	NA	NA|838aa|down_0|NZ_CP023607.1_336452_338966_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP023607.1_339256_340867_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP023607.1_340890_341799_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP023607.1_342022_343918_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP023607.1_343914_345531_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP023607.1_345527_349520_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP023607.1_349516_349825_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP023607.1_349827_351369_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP023607.1_351417_351711_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP023607.1_351740_352031_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	2	334411-334598	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGTTGCCGAACAACCACCCGCCGGCCCCGCCGGCAGCCCCGGT	44	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP023607.1_333070_333253_-,NA	NA|398aa|up_9|NZ_CP023607.1_323248_324442_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP023607.1_324477_326160_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP023607.1_326176_328372_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP023607.1_328485_329619_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP023607.1_329615_330236_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP023607.1_330332_330914_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP023607.1_330843_331569_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP023607.1_331658_332579_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP023607.1_332618_333047_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP023607.1_333070_333253_-	NA	NA|838aa|down_0|NZ_CP023607.1_336452_338966_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP023607.1_339256_340867_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP023607.1_340890_341799_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP023607.1_342022_343918_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP023607.1_343914_345531_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP023607.1_345527_349520_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP023607.1_349516_349825_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP023607.1_349827_351369_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP023607.1_351417_351711_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP023607.1_351740_352031_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	3	366356-367054	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366644-366685|366719-366751	NZ_CP023607.1_374675-374716|NZ_CP023607.1_373490-373522	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023607.1_363368_363671_+,NA|161aa|down_1|NZ_CP023607.1_376464_376947_-,NA|410aa|down_5|NZ_CP023607.1_379063_380293_+	NA|262aa|up_9|NZ_CP023607.1_358063_358849_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023607.1_358837_359641_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023607.1_359650_361048_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023607.1_361226_363002_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023607.1_363144_363372_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023607.1_363368_363671_+	NA	NA|74aa|up_3|NZ_CP023607.1_363718_363940_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023607.1_363936_364362_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023607.1_364497_365130_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023607.1_365126_366035_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023607.1_375805_376477_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023607.1_376464_376947_-	NA	NA|239aa|down_2|NZ_CP023607.1_377004_377721_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023607.1_377822_378479_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023607.1_378548_379040_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023607.1_379063_380293_+	NA	NA|621aa|down_6|NZ_CP023607.1_380447_382310_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023607.1_382381_382768_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023607.1_382770_383433_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023607.1_383493_384378_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	4	691853-691929	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023607.1_677537_677753_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023607.1_677749_678157_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023607.1_678216_678903_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023607.1_679056_681690_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023607.1_681712_684100_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023607.1_684237_684960_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023607.1_684956_685754_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023607.1_685755_686643_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023607.1_686648_687863_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023607.1_688886_690332_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023607.1_693064_694615_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023607.1_694666_695059_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023607.1_695055_695313_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023607.1_695495_696731_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023607.1_696981_697395_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023607.1_697391_697628_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023607.1_697731_698238_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023607.1_698351_698822_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023607.1_698865_699627_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023607.1_699683_699995_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	5	1191108-1191216	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023607.1_1180475_1182107_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023607.1_1182182_1183247_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023607.1_1183299_1183773_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023607.1_1183806_1184670_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023607.1_1184674_1185532_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023607.1_1185532_1186615_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023607.1_1186695_1187115_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023607.1_1187226_1187793_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023607.1_1187789_1188185_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023607.1_1188212_1190216_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023607.1_1192301_1194065_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023607.1_1194061_1194835_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023607.1_1194846_1195884_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023607.1_1196070_1196907_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023607.1_1197022_1197874_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023607.1_1197947_1199165_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023607.1_1199217_1200162_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023607.1_1200384_1201452_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023607.1_1201508_1202903_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023607.1_1203104_1203827_+	pfam06271, RDD, RDD family
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	6	2088035-2088289	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088116-2088133|2088116-2088133|2088206-2088223	NZ_CP023607.1_400971-400954|NZ_CP023607.1_607287-607270|NZ_CP023607.1_3449945-3449928	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023607.1_2087394_2087658_-,NA	NA|165aa|up_9|NZ_CP023607.1_2073688_2074183_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023607.1_2074586_2075264_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023607.1_2075622_2078448_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023607.1_2078674_2079535_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023607.1_2079575_2080442_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023607.1_2080446_2082333_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023607.1_2082348_2084382_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023607.1_2084501_2086727_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023607.1_2087002_2087398_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023607.1_2087394_2087658_-	NA	NA|346aa|down_0|NZ_CP023607.1_2089426_2090464_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023607.1_2090463_2091831_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023607.1_2092004_2093441_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023607.1_2093476_2094928_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023607.1_2094957_2095908_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023607.1_2095922_2096339_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023607.1_2096616_2097039_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023607.1_2097087_2097390_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023607.1_2097386_2097701_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023607.1_2097700_2099434_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	7	2163127-2163231	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023607.1_2159671_2160079_-,NA|127aa|down_6|NZ_CP023607.1_2176300_2176681_-	NA|216aa|up_9|NZ_CP023607.1_2152985_2153633_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023607.1_2153639_2155862_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023607.1_2155899_2156343_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023607.1_2156456_2157050_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023607.1_2157132_2157738_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023607.1_2157837_2158842_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023607.1_2158941_2159694_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023607.1_2159671_2160079_-	NA	NA|368aa|up_1|NZ_CP023607.1_2160213_2161317_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023607.1_2161316_2162513_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023607.1_2167399_2170363_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023607.1_2170811_2171276_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023607.1_2171373_2172237_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023607.1_2172274_2173546_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023607.1_2173817_2174933_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023607.1_2174923_2176264_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023607.1_2176300_2176681_-	NA	NA|621aa|down_7|NZ_CP023607.1_2176837_2178700_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023607.1_2178707_2179187_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023607.1_2179423_2180197_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	8	2168565-2168784	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP023607.1_2159671_2160079_-,NA|127aa|down_5|NZ_CP023607.1_2176300_2176681_-	NA|741aa|up_9|NZ_CP023607.1_2153639_2155862_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023607.1_2155899_2156343_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023607.1_2156456_2157050_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023607.1_2157132_2157738_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023607.1_2157837_2158842_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023607.1_2158941_2159694_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023607.1_2159671_2160079_-	NA	NA|368aa|up_2|NZ_CP023607.1_2160213_2161317_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023607.1_2161316_2162513_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023607.1_2162682_2167062_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023607.1_2170811_2171276_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023607.1_2171373_2172237_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023607.1_2172274_2173546_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023607.1_2173817_2174933_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023607.1_2174923_2176264_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023607.1_2176300_2176681_-	NA	NA|621aa|down_6|NZ_CP023607.1_2176837_2178700_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023607.1_2178707_2179187_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023607.1_2179423_2180197_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023607.1_2180200_2180968_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	9	3118934-3120288	2,6,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023607.1_3112213_3112468_-,NA|135aa|up_7|NZ_CP023607.1_3112615_3113020_+,NA|64aa|up_6|NZ_CP023607.1_3113016_3113208_+,NA|86aa|up_4|NZ_CP023607.1_3114794_3115052_+,NA|104aa|up_3|NZ_CP023607.1_3115156_3115468_+,NA|203aa|up_2|NZ_CP023607.1_3115887_3116496_+,NA	NA|92aa|up_9|NZ_CP023607.1_3111762_3112038_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023607.1_3112213_3112468_-	NA	NA|135aa|up_7|NZ_CP023607.1_3112615_3113020_+	NA	NA|64aa|up_6|NZ_CP023607.1_3113016_3113208_+	NA	NA|385aa|up_5|NZ_CP023607.1_3113406_3114561_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023607.1_3114794_3115052_+	NA	NA|104aa|up_3|NZ_CP023607.1_3115156_3115468_+	NA	NA|203aa|up_2|NZ_CP023607.1_3115887_3116496_+	NA	NA|470aa|up_1|NZ_CP023607.1_3116566_3117976_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023607.1_3117972_3118785_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023607.1_3120314_3121576_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023607.1_3123373_3123715_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023607.1_3123715_3124732_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023607.1_3124744_3125893_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023607.1_3125988_3127116_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023607.1_3127112_3128021_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023607.1_3128001_3128712_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023607.1_3128721_3129096_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_8|NZ_CP023607.1_3129092_3131522_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023607.1_3131518_3132241_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	10	3121611-3123325	4,3,7	CRT,PILER-CR,CRISPRCasFinder	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,22,22	23	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023607.1_3112213_3112468_-,NA|135aa|up_8|NZ_CP023607.1_3112615_3113020_+,NA|64aa|up_7|NZ_CP023607.1_3113016_3113208_+,NA|86aa|up_5|NZ_CP023607.1_3114794_3115052_+,NA|104aa|up_4|NZ_CP023607.1_3115156_3115468_+,NA|203aa|up_3|NZ_CP023607.1_3115887_3116496_+,NA	NA|85aa|up_9|NZ_CP023607.1_3112213_3112468_-	NA	NA|135aa|up_8|NZ_CP023607.1_3112615_3113020_+	NA	NA|64aa|up_7|NZ_CP023607.1_3113016_3113208_+	NA	NA|385aa|up_6|NZ_CP023607.1_3113406_3114561_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023607.1_3114794_3115052_+	NA	NA|104aa|up_4|NZ_CP023607.1_3115156_3115468_+	NA	NA|203aa|up_3|NZ_CP023607.1_3115887_3116496_+	NA	NA|470aa|up_2|NZ_CP023607.1_3116566_3117976_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023607.1_3117972_3118785_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023607.1_3120314_3121576_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023607.1_3123373_3123715_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023607.1_3123715_3124732_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023607.1_3124744_3125893_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023607.1_3125988_3127116_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023607.1_3127112_3128021_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023607.1_3128001_3128712_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023607.1_3128721_3129096_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_7|NZ_CP023607.1_3129092_3131522_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023607.1_3131518_3132241_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023607.1_3132640_3133186_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	11	3740365-3740906	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023607.1_3754998_3755286_-,NA|87aa|down_9|NZ_CP023607.1_3768406_3768667_-	NA|282aa|up_9|NZ_CP023607.1_3719616_3720462_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023607.1_3720936_3721377_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023607.1_3721410_3722280_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023607.1_3722300_3723311_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023607.1_3723595_3724228_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023607.1_3724294_3725524_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023607.1_3725806_3727156_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023607.1_3727167_3728307_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023607.1_3728303_3729035_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023607.1_3729043_3736615_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023607.1_3742868_3743126_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023607.1_3743381_3752855_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023607.1_3753480_3753927_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023607.1_3753963_3754704_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023607.1_3754998_3755286_-	NA	NA|3717aa|down_5|NZ_CP023607.1_3755622_3766773_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023607.1_3767016_3767811_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023607.1_3767892_3768264_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023607.1_3768161_3768380_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023607.1_3768406_3768667_-	NA
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	12	3947970-3949068	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCNNNGGCGGNNNCGGCGGC	37	9	13	3948097-3948143|3948181-3948215|3948484-3948524|3948562-3948596|3948562-3948596|3948562-3948596|3948562-3948596|3948562-3948596|3948634-3948668|3948706-3948752|3948790-3948815|3948853-3948878|3948916-3948941	NZ_CP023607.1_3949297-3949343|NZ_CP023607.1_3949381-3949415|NZ_CP023607.1_3949087-3949127|NZ_CP023607.1_3946678-3946712|NZ_CP023607.1_3947020-3947054|NZ_CP023607.1_3947611-3947645|NZ_CP023607.1_3947962-3947996|NZ_CP023607.1_3932474-3932508|NZ_CP023607.1_3949234-3949268|NZ_CP023607.1_3949306-3949352|NZ_CP023607.1_3949390-3949415|NZ_CP023607.1_3949453-3949478|NZ_CP023607.1_3949516-3949541	NA	14	14	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP023607.1_3953036_3953876_+	NA|318aa|up_9|NZ_CP023607.1_3920755_3921709_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP023607.1_3921733_3921925_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP023607.1_3922139_3923342_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP023607.1_3923366_3924488_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP023607.1_3924558_3926067_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1382aa|up_4|NZ_CP023607.1_3926237_3930383_+	pfam00934, PE, PE family	NA|1884aa|up_3|NZ_CP023607.1_3930673_3936325_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP023607.1_3936491_3938039_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP023607.1_3938035_3938872_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP023607.1_3944697_3945354_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023607.1_3950429_3952076_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023607.1_3952149_3952941_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023607.1_3953036_3953876_+	NA	NA|399aa|down_3|NZ_CP023607.1_3953930_3955127_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023607.1_3955155_3955866_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023607.1_3955930_3956974_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023607.1_3957126_3958038_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023607.1_3958053_3959118_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023607.1_3959134_3960319_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023607.1_3960360_3961392_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002447555.1_ASM244755v1	NZ_CP023607	Mycobacterium tuberculosis strain LE371 chromosome, complete genome	13	4110279-4110367	8	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023607.1_4100865_4101636_-,NA|119aa|up_3|NZ_CP023607.1_4106770_4107127_+,NA|52aa|up_2|NZ_CP023607.1_4107226_4107382_+,NA|233aa|up_0|NZ_CP023607.1_4109383_4110082_-,NA|126aa|down_6|NZ_CP023607.1_4115602_4115980_+	NA|288aa|up_9|NZ_CP023607.1_4099247_4100111_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023607.1_4100865_4101636_-	NA	NA|549aa|up_7|NZ_CP023607.1_4101632_4103279_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023607.1_4103275_4104139_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023607.1_4104131_4105058_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023607.1_4105059_4106685_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023607.1_4106770_4107127_+	NA	NA|52aa|up_2|NZ_CP023607.1_4107226_4107382_+	NA	NA|652aa|up_1|NZ_CP023607.1_4107392_4109348_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023607.1_4109383_4110082_-	NA	NA|173aa|down_0|NZ_CP023607.1_4110427_4110946_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023607.1_4110946_4111930_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023607.1_4111922_4113116_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023607.1_4113121_4113943_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023607.1_4114074_4114758_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023607.1_4114757_4115495_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023607.1_4115602_4115980_+	NA	NA|225aa|down_7|NZ_CP023607.1_4116078_4116753_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023607.1_4116858_4117653_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023607.1_4117659_4118115_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
