assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	1	338083-338305	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_CP023590.1_333156_333339_-,NA	NA|561aa|up_9|NZ_CP023590.1_324563_326246_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP023590.1_326262_328458_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP023590.1_328571_329705_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP023590.1_329701_330322_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP023590.1_330418_331000_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP023590.1_330929_331655_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP023590.1_331744_332665_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP023590.1_332704_333133_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP023590.1_333156_333339_-	NA	NA|631aa|up_0|NZ_CP023590.1_333385_335278_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|537aa|down_0|NZ_CP023590.1_339342_340953_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP023590.1_340976_341885_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP023590.1_342108_344004_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP023590.1_344000_345617_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP023590.1_345613_349606_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP023590.1_349602_349911_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP023590.1_349913_351455_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP023590.1_351503_351797_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP023590.1_351826_352117_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP023590.1_352127_353015_+	pfam14011, ESX-1_EspG, EspG family
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	2	366442-367140	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366730-366771|366805-366837	NZ_CP023590.1_374761-374802|NZ_CP023590.1_373576-373608	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023590.1_363454_363757_+,NA|161aa|down_1|NZ_CP023590.1_376550_377033_-,NA|410aa|down_5|NZ_CP023590.1_379149_380379_+	NA|262aa|up_9|NZ_CP023590.1_358149_358935_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023590.1_358923_359727_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023590.1_359736_361134_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023590.1_361312_363088_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023590.1_363230_363458_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023590.1_363454_363757_+	NA	NA|74aa|up_3|NZ_CP023590.1_363804_364026_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023590.1_364022_364448_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023590.1_364583_365216_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023590.1_365212_366121_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023590.1_375891_376563_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023590.1_376550_377033_-	NA	NA|239aa|down_2|NZ_CP023590.1_377090_377807_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023590.1_377908_378565_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023590.1_378634_379126_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023590.1_379149_380379_+	NA	NA|621aa|down_6|NZ_CP023590.1_380533_382396_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023590.1_382467_382854_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023590.1_382856_383519_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023590.1_383579_384464_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	3	691901-691977	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023590.1_677585_677801_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023590.1_677797_678205_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023590.1_678264_678951_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023590.1_679104_681738_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023590.1_681760_684148_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023590.1_684285_685008_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023590.1_685004_685802_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023590.1_685803_686691_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023590.1_686696_687911_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023590.1_688934_690380_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023590.1_693112_694663_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023590.1_694714_695107_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023590.1_695103_695361_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023590.1_695543_696779_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023590.1_697029_697443_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023590.1_697439_697676_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023590.1_697779_698286_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023590.1_698399_698870_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023590.1_698913_699675_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023590.1_699731_700043_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	4	840360-840482	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGGCCCCGCCGGCCCCGCCGGTGCCG--------GCG	42	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|71aa|up_9|NZ_CP023590.1_829575_829788_+,NA|176aa|up_6|NZ_CP023590.1_831650_832178_+,NA|186aa|up_4|NZ_CP023590.1_833760_834318_-,NA|46aa|down_2|NZ_CP023590.1_841611_841749_-,NA|53aa|down_3|NZ_CP023590.1_841734_841893_+,NA|82aa|down_4|NZ_CP023590.1_841907_842153_+	NA|71aa|up_9|NZ_CP023590.1_829575_829788_+	NA	NA|183aa|up_8|NZ_CP023590.1_829936_830485_+	TIGR03086, TIGR03086, TIGR03086 family protein	NA|269aa|up_7|NZ_CP023590.1_830729_831536_+	pfam10774, DUF4226, Domain of unknown function (DUF4226)	NA|176aa|up_6|NZ_CP023590.1_831650_832178_+	NA	NA|176aa|up_5|NZ_CP023590.1_832855_833383_+	pfam00934, PE, PE family	NA|186aa|up_4|NZ_CP023590.1_833760_834318_-	NA	NA|169aa|up_3|NZ_CP023590.1_834314_834821_-	pfam12728, HTH_17, Helix-turn-helix domain	NA|49aa|up_2|NZ_CP023590.1_834933_835080_-	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase	NA|176aa|up_1|NZ_CP023590.1_835028_835556_+	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase	NA|784aa|up_0|NZ_CP023590.1_835575_837927_+	pfam00934, PE, PE family	NA|86aa|down_0|NZ_CP023590.1_840821_841079_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|143aa|down_1|NZ_CP023590.1_841102_841531_+	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|46aa|down_2|NZ_CP023590.1_841611_841749_-	NA	NA|53aa|down_3|NZ_CP023590.1_841734_841893_+	NA	NA|82aa|down_4|NZ_CP023590.1_841907_842153_+	NA	NA|295aa|down_5|NZ_CP023590.1_842221_843106_-	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase	NA|391aa|down_6|NZ_CP023590.1_843116_844289_-	cd01162, IBD, Isobutyryl-CoA dehydrogenase	NA|511aa|down_7|NZ_CP023590.1_844295_845828_-	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2	NA|585aa|down_8|NZ_CP023590.1_846033_847788_+	pfam00934, PE, PE family	NA|646aa|down_9|NZ_CP023590.1_847977_849915_-	pfam00823, PPE, PPE family
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	5	926497-927444	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927280-927315|927280-927315|927280-927315	NZ_CP023590.1_675004-674969|NZ_CP023590.1_1213635-1213670|NZ_CP023590.1_2423610-2423575	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023590.1_931454_932006_-,NA|81aa|down_8|NZ_CP023590.1_937469_937712_+	NA|685aa|up_9|NZ_CP023590.1_914133_916188_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023590.1_916353_917523_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023590.1_917610_918627_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023590.1_918788_919430_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023590.1_919510_920566_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023590.1_920617_921010_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023590.1_921067_921490_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023590.1_921451_921742_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023590.1_921846_922752_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023590.1_922770_923586_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023590.1_927713_930362_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023590.1_930829_931474_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023590.1_931454_932006_-	NA	NA|218aa|down_3|NZ_CP023590.1_932155_932809_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023590.1_932879_933908_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023590.1_934596_935367_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023590.1_935453_936266_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023590.1_936333_937194_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023590.1_937469_937712_+	NA	NA|431aa|down_9|NZ_CP023590.1_937988_939281_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	6	1191202-1191310	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023590.1_1180569_1182201_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023590.1_1182276_1183341_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023590.1_1183393_1183867_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023590.1_1183900_1184764_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023590.1_1184768_1185626_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023590.1_1185626_1186709_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023590.1_1186789_1187209_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023590.1_1187320_1187887_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023590.1_1187883_1188279_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023590.1_1188306_1190310_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023590.1_1192395_1194159_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023590.1_1194155_1194929_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023590.1_1194940_1195978_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023590.1_1196164_1197001_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023590.1_1197116_1197968_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023590.1_1198041_1199259_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023590.1_1199311_1200256_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023590.1_1200478_1201546_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023590.1_1201602_1202997_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023590.1_1203198_1203921_+	pfam06271, RDD, RDD family
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	7	1211836-1212692	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	75	1212219-1212240|1212264-1212279|1212402-1212423|1212402-1212423|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537|1212519-1212537	NZ_CP023590.1_2960377-2960356|NZ_CP023590.1_2088495-2088480|NZ_CP023590.1_837309-837330|NZ_CP023590.1_1217530-1217551|NZ_CP023590.1_1572714-1572696|NZ_CP023590.1_674668-674650|NZ_CP023590.1_1213362-1213380|NZ_CP023590.1_1217503-1217521|NZ_CP023590.1_1217575-1217593|NZ_CP023590.1_1630586-1630568|NZ_CP023590.1_1633412-1633394|NZ_CP023590.1_1990699-1990681|NZ_CP023590.1_2061423-2061405|NZ_CP023590.1_2061870-2061852|NZ_CP023590.1_2061969-2061951|NZ_CP023590.1_2801926-2801908|NZ_CP023590.1_2805454-2805436|NZ_CP023590.1_1636807-1636789|NZ_CP023590.1_150187-150205|NZ_CP023590.1_333779-333761|NZ_CP023590.1_335198-335180|NZ_CP023590.1_335651-335633|NZ_CP023590.1_335702-335684|NZ_CP023590.1_335711-335693|NZ_CP023590.1_337982-337964|NZ_CP023590.1_338378-338360|NZ_CP023590.1_338407-338425|NZ_CP023590.1_338501-338483|NZ_CP023590.1_363032-363014|NZ_CP023590.1_443334-443316|NZ_CP023590.1_546678-546660|NZ_CP023590.1_623868-623886|NZ_CP023590.1_624090-624108|NZ_CP023590.1_673834-673816|NZ_CP023590.1_840092-840110|NZ_CP023590.1_1090865-1090883|NZ_CP023590.1_1091513-1091531|NZ_CP023590.1_1095571-1095553|NZ_CP023590.1_1212891-1212909|NZ_CP023590.1_1213281-1213299|NZ_CP023590.1_1217923-1217941|NZ_CP023590.1_1489098-1489080|NZ_CP023590.1_1618550-1618532|NZ_CP023590.1_1619003-1618985|NZ_CP023590.1_1635925-1635907|NZ_CP023590.1_1635934-1635916|NZ_CP023590.1_1864213-1864195|NZ_CP023590.1_1864741-1864723|NZ_CP023590.1_1989973-1989955|NZ_CP023590.1_2001335-2001353|NZ_CP023590.1_2088693-2088675|NZ_CP023590.1_2303393-2303375|NZ_CP023590.1_2356844-2356826|NZ_CP023590.1_2419436-2419454|NZ_CP023590.1_2423523-2423505|NZ_CP023590.1_2569016-2568998|NZ_CP023590.1_2693314-2693332|NZ_CP023590.1_2795241-2795223|NZ_CP023590.1_2795823-2795805|NZ_CP023590.1_3054413-3054431|NZ_CP023590.1_3054512-3054530|NZ_CP023590.1_3705322-3705340|NZ_CP023590.1_3737299-3737281|NZ_CP023590.1_3737923-3737905|NZ_CP023590.1_3738166-3738148|NZ_CP023590.1_3738299-3738281|NZ_CP023590.1_3802144-3802162|NZ_CP023590.1_3802327-3802345|NZ_CP023590.1_3802495-3802513|NZ_CP023590.1_3930311-3930329|NZ_CP023590.1_3932041-3932059|NZ_CP023590.1_3940549-3940567|NZ_CP023590.1_3948544-3948562|NZ_CP023590.1_4031524-4031506|NZ_CP023590.1_4094055-4094073	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023590.1_1207268_1207535_+,NA|61aa|down_3|NZ_CP023590.1_1215110_1215293_+,NA|35aa|down_4|NZ_CP023590.1_1215402_1215507_+	NA|465aa|up_9|NZ_CP023590.1_1201602_1202997_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023590.1_1203198_1203921_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023590.1_1203952_1205119_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023590.1_1205189_1205684_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023590.1_1205869_1206304_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023590.1_1206405_1207272_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023590.1_1207268_1207535_+	NA	NA|674aa|up_2|NZ_CP023590.1_1207521_1209543_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023590.1_1209641_1210370_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023590.1_1210480_1211269_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023590.1_1213925_1214246_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023590.1_1214398_1214833_+	pfam00934, PE, PE family	NA|55aa|down_2|NZ_CP023590.1_1214934_1215099_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023590.1_1215110_1215293_+	NA	NA|35aa|down_4|NZ_CP023590.1_1215402_1215507_+	NA	NA|152aa|down_5|NZ_CP023590.1_1215484_1215940_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023590.1_1216354_1218916_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023590.1_1219133_1220072_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023590.1_1220459_1221740_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023590.1_1221844_1222672_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	8	2088165-2088419	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088246-2088263|2088246-2088263|2088336-2088353	NZ_CP023590.1_401057-401040|NZ_CP023590.1_607323-607306|NZ_CP023590.1_3450022-3450005	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023590.1_2087524_2087788_-,NA	NA|165aa|up_9|NZ_CP023590.1_2073818_2074313_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023590.1_2074716_2075394_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023590.1_2075752_2078578_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023590.1_2078804_2079665_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023590.1_2079705_2080572_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023590.1_2080576_2082463_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023590.1_2082478_2084512_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023590.1_2084631_2086857_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023590.1_2087132_2087528_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023590.1_2087524_2087788_-	NA	NA|346aa|down_0|NZ_CP023590.1_2089556_2090594_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023590.1_2090593_2091961_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023590.1_2092134_2093571_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023590.1_2093606_2095058_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023590.1_2095087_2096038_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023590.1_2096052_2096469_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023590.1_2096746_2097169_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023590.1_2097217_2097520_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023590.1_2097516_2097831_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023590.1_2097830_2099564_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	9	2163257-2163361	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023590.1_2159801_2160209_-,NA|127aa|down_6|NZ_CP023590.1_2176430_2176811_-	NA|216aa|up_9|NZ_CP023590.1_2153115_2153763_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023590.1_2153769_2155992_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023590.1_2156029_2156473_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023590.1_2156586_2157180_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023590.1_2157262_2157868_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023590.1_2157967_2158972_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023590.1_2159071_2159824_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023590.1_2159801_2160209_-	NA	NA|368aa|up_1|NZ_CP023590.1_2160343_2161447_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023590.1_2161446_2162643_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023590.1_2167529_2170493_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023590.1_2170941_2171406_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023590.1_2171503_2172367_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023590.1_2172404_2173676_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023590.1_2173947_2175063_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023590.1_2175053_2176394_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023590.1_2176430_2176811_-	NA	NA|621aa|down_7|NZ_CP023590.1_2176967_2178830_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023590.1_2178837_2179317_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023590.1_2179553_2180327_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	10	2168695-2168914	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP023590.1_2159801_2160209_-,NA|127aa|down_5|NZ_CP023590.1_2176430_2176811_-	NA|741aa|up_9|NZ_CP023590.1_2153769_2155992_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023590.1_2156029_2156473_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023590.1_2156586_2157180_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023590.1_2157262_2157868_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023590.1_2157967_2158972_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023590.1_2159071_2159824_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023590.1_2159801_2160209_-	NA	NA|368aa|up_2|NZ_CP023590.1_2160343_2161447_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023590.1_2161446_2162643_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023590.1_2162812_2167192_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023590.1_2170941_2171406_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023590.1_2171503_2172367_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023590.1_2172404_2173676_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023590.1_2173947_2175063_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023590.1_2175053_2176394_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023590.1_2176430_2176811_-	NA	NA|621aa|down_6|NZ_CP023590.1_2176967_2178830_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023590.1_2178837_2179317_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023590.1_2179553_2180327_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023590.1_2180330_2181098_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	11	3119004-3120358	3,7,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-B,Type III-A,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-D,TypeIII-B,TypeIII-A,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023590.1_3112283_3112538_-,NA|135aa|up_7|NZ_CP023590.1_3112685_3113090_+,NA|64aa|up_6|NZ_CP023590.1_3113086_3113278_+,NA|86aa|up_4|NZ_CP023590.1_3114864_3115122_+,NA|104aa|up_3|NZ_CP023590.1_3115226_3115538_+,NA|203aa|up_2|NZ_CP023590.1_3115957_3116566_+,NA	NA|92aa|up_9|NZ_CP023590.1_3111832_3112108_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023590.1_3112283_3112538_-	NA	NA|135aa|up_7|NZ_CP023590.1_3112685_3113090_+	NA	NA|64aa|up_6|NZ_CP023590.1_3113086_3113278_+	NA	NA|385aa|up_5|NZ_CP023590.1_3113476_3114631_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023590.1_3114864_3115122_+	NA	NA|104aa|up_3|NZ_CP023590.1_3115226_3115538_+	NA	NA|203aa|up_2|NZ_CP023590.1_3115957_3116566_+	NA	NA|470aa|up_1|NZ_CP023590.1_3116636_3118046_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023590.1_3118042_3118855_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023590.1_3120384_3121646_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023590.1_3123443_3123785_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023590.1_3123785_3124802_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023590.1_3124814_3125963_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023590.1_3126058_3127186_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023590.1_3127182_3128091_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023590.1_3128071_3128782_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023590.1_3128791_3129166_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023590.1_3129162_3131601_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023590.1_3131597_3132320_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	12	3121681-3123395	8,4,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-B,Type III-A,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-D,TypeIII-B,TypeIII-A,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023590.1_3112283_3112538_-,NA|135aa|up_8|NZ_CP023590.1_3112685_3113090_+,NA|64aa|up_7|NZ_CP023590.1_3113086_3113278_+,NA|86aa|up_5|NZ_CP023590.1_3114864_3115122_+,NA|104aa|up_4|NZ_CP023590.1_3115226_3115538_+,NA|203aa|up_3|NZ_CP023590.1_3115957_3116566_+,NA	NA|85aa|up_9|NZ_CP023590.1_3112283_3112538_-	NA	NA|135aa|up_8|NZ_CP023590.1_3112685_3113090_+	NA	NA|64aa|up_7|NZ_CP023590.1_3113086_3113278_+	NA	NA|385aa|up_6|NZ_CP023590.1_3113476_3114631_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023590.1_3114864_3115122_+	NA	NA|104aa|up_4|NZ_CP023590.1_3115226_3115538_+	NA	NA|203aa|up_3|NZ_CP023590.1_3115957_3116566_+	NA	NA|470aa|up_2|NZ_CP023590.1_3116636_3118046_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023590.1_3118042_3118855_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023590.1_3120384_3121646_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023590.1_3123443_3123785_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023590.1_3123785_3124802_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023590.1_3124814_3125963_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023590.1_3126058_3127186_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023590.1_3127182_3128091_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023590.1_3128071_3128782_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023590.1_3128791_3129166_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023590.1_3129162_3131601_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023590.1_3131597_3132320_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023590.1_3132719_3133265_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	13	3740493-3741034	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023590.1_3755117_3755405_-,NA|87aa|down_9|NZ_CP023590.1_3768525_3768786_-	NA|282aa|up_9|NZ_CP023590.1_3719744_3720590_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023590.1_3721064_3721505_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023590.1_3721538_3722408_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023590.1_3722428_3723439_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023590.1_3723723_3724356_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023590.1_3724422_3725652_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023590.1_3725934_3727284_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023590.1_3727295_3728435_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023590.1_3728431_3729163_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023590.1_3729171_3736743_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023590.1_3742987_3743245_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023590.1_3743500_3752974_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023590.1_3753599_3754046_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023590.1_3754082_3754823_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023590.1_3755117_3755405_-	NA	NA|3717aa|down_5|NZ_CP023590.1_3755741_3766892_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023590.1_3767135_3767930_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023590.1_3768011_3768383_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023590.1_3768280_3768499_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023590.1_3768525_3768786_-	NA
GCF_002447215.1_ASM244721v1	NZ_CP023590	Mycobacterium tuberculosis strain TBV5362 chromosome, complete genome	14	4110472-4110560	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023590.1_4101058_4101829_-,NA|119aa|up_3|NZ_CP023590.1_4106963_4107320_+,NA|52aa|up_2|NZ_CP023590.1_4107419_4107575_+,NA|233aa|up_0|NZ_CP023590.1_4109576_4110275_-,NA|126aa|down_6|NZ_CP023590.1_4115795_4116173_+	NA|288aa|up_9|NZ_CP023590.1_4099440_4100304_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023590.1_4101058_4101829_-	NA	NA|549aa|up_7|NZ_CP023590.1_4101825_4103472_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023590.1_4103468_4104332_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023590.1_4104324_4105251_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023590.1_4105252_4106878_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023590.1_4106963_4107320_+	NA	NA|52aa|up_2|NZ_CP023590.1_4107419_4107575_+	NA	NA|652aa|up_1|NZ_CP023590.1_4107585_4109541_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023590.1_4109576_4110275_-	NA	NA|173aa|down_0|NZ_CP023590.1_4110620_4111139_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023590.1_4111139_4112123_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023590.1_4112115_4113309_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023590.1_4113314_4114136_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023590.1_4114267_4114951_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023590.1_4114950_4115688_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023590.1_4115795_4116173_+	NA	NA|225aa|down_7|NZ_CP023590.1_4116271_4116946_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023590.1_4117051_4117846_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023590.1_4117852_4118308_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
