assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	1	366448-367146	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366736-366777|366811-366843	NZ_CP023587.1_374767-374808|NZ_CP023587.1_373582-373614	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|101aa|up_4|NZ_CP023587.1_363460_363763_+,NA|161aa|down_1|NZ_CP023587.1_376556_377039_-,NA|410aa|down_5|NZ_CP023587.1_379155_380385_+	NA|262aa|up_9|NZ_CP023587.1_358155_358941_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023587.1_358929_359733_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023587.1_359742_361140_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023587.1_361318_363094_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023587.1_363236_363464_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023587.1_363460_363763_+	NA	NA|74aa|up_3|NZ_CP023587.1_363810_364032_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023587.1_364028_364454_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023587.1_364589_365222_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023587.1_365218_366127_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023587.1_375897_376569_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023587.1_376556_377039_-	NA	NA|239aa|down_2|NZ_CP023587.1_377096_377813_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023587.1_377914_378571_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023587.1_378640_379132_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023587.1_379155_380385_+	NA	NA|621aa|down_6|NZ_CP023587.1_380539_382402_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023587.1_382473_382860_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023587.1_382862_383525_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023587.1_383585_384470_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	2	691875-691951	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|136aa|up_9|NZ_CP023587.1_677770_678178_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP023587.1_678237_678924_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP023587.1_679077_681711_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP023587.1_681733_684121_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP023587.1_684258_684981_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP023587.1_684977_685775_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP023587.1_685776_686664_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP023587.1_686669_687884_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_1|NZ_CP023587.1_688907_690353_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|479aa|up_0|NZ_CP023587.1_690349_691786_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023587.1_693086_694637_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023587.1_694688_695081_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023587.1_695077_695335_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023587.1_695517_696753_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023587.1_697003_697417_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023587.1_697413_697650_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023587.1_697753_698260_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023587.1_698373_698844_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023587.1_698887_699649_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023587.1_699705_700017_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	3	926443-927381	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927226-927261|927226-927261|927226-927261	NZ_CP023587.1_674977-674942|NZ_CP023587.1_1213566-1213601|NZ_CP023587.1_2423534-2423499	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|184aa|down_2|NZ_CP023587.1_931391_931943_-,NA|81aa|down_8|NZ_CP023587.1_937406_937649_+	NA|685aa|up_9|NZ_CP023587.1_914079_916134_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023587.1_916299_917469_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023587.1_917556_918573_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023587.1_918734_919376_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023587.1_919456_920512_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023587.1_920563_920956_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023587.1_921013_921436_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023587.1_921397_921688_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023587.1_921792_922698_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023587.1_922716_923532_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023587.1_927650_930299_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023587.1_930766_931411_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023587.1_931391_931943_-	NA	NA|218aa|down_3|NZ_CP023587.1_932092_932746_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023587.1_932816_933845_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023587.1_934533_935304_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023587.1_935390_936203_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023587.1_936270_937131_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023587.1_937406_937649_+	NA	NA|431aa|down_9|NZ_CP023587.1_937925_939218_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	4	1191133-1191241	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|544aa|up_9|NZ_CP023587.1_1180500_1182132_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023587.1_1182207_1183272_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023587.1_1183324_1183798_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023587.1_1183831_1184695_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023587.1_1184699_1185557_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023587.1_1185557_1186640_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023587.1_1186720_1187140_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023587.1_1187251_1187818_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023587.1_1187814_1188210_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023587.1_1188237_1190241_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023587.1_1192326_1194090_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023587.1_1194086_1194860_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023587.1_1194871_1195909_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023587.1_1196095_1196932_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023587.1_1197047_1197899_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023587.1_1197972_1199190_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023587.1_1199242_1200187_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023587.1_1200409_1201477_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023587.1_1201533_1202928_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023587.1_1203129_1203852_+	pfam06271, RDD, RDD family
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	5	1211767-1212623	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	72	1212150-1212171|1212195-1212210|1212333-1212354|1212333-1212354|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468|1212450-1212468	NZ_CP023587.1_2960299-2960278|NZ_CP023587.1_2088419-2088404|NZ_CP023587.1_837255-837276|NZ_CP023587.1_1217461-1217482|NZ_CP023587.1_674641-674623|NZ_CP023587.1_1213293-1213311|NZ_CP023587.1_1217434-1217452|NZ_CP023587.1_1217506-1217524|NZ_CP023587.1_1630509-1630491|NZ_CP023587.1_1633335-1633317|NZ_CP023587.1_1990622-1990604|NZ_CP023587.1_2061347-2061329|NZ_CP023587.1_2061794-2061776|NZ_CP023587.1_2061893-2061875|NZ_CP023587.1_2801848-2801830|NZ_CP023587.1_2805376-2805358|NZ_CP023587.1_150188-150206|NZ_CP023587.1_333788-333770|NZ_CP023587.1_335204-335186|NZ_CP023587.1_335657-335639|NZ_CP023587.1_335708-335690|NZ_CP023587.1_335717-335699|NZ_CP023587.1_337988-337970|NZ_CP023587.1_338117-338099|NZ_CP023587.1_338384-338366|NZ_CP023587.1_338413-338431|NZ_CP023587.1_338507-338489|NZ_CP023587.1_363038-363020|NZ_CP023587.1_443311-443293|NZ_CP023587.1_546642-546624|NZ_CP023587.1_623832-623850|NZ_CP023587.1_624054-624072|NZ_CP023587.1_673807-673789|NZ_CP023587.1_840038-840056|NZ_CP023587.1_1090800-1090818|NZ_CP023587.1_1091448-1091466|NZ_CP023587.1_1095506-1095488|NZ_CP023587.1_1212822-1212840|NZ_CP023587.1_1213212-1213230|NZ_CP023587.1_1217854-1217872|NZ_CP023587.1_1489029-1489011|NZ_CP023587.1_1618926-1618908|NZ_CP023587.1_1635848-1635830|NZ_CP023587.1_1635857-1635839|NZ_CP023587.1_1864136-1864118|NZ_CP023587.1_1864664-1864646|NZ_CP023587.1_1989896-1989878|NZ_CP023587.1_2001259-2001277|NZ_CP023587.1_2088617-2088599|NZ_CP023587.1_2303317-2303299|NZ_CP023587.1_2356769-2356751|NZ_CP023587.1_2419360-2419378|NZ_CP023587.1_2423447-2423429|NZ_CP023587.1_2568940-2568922|NZ_CP023587.1_2693239-2693257|NZ_CP023587.1_2795163-2795145|NZ_CP023587.1_2795745-2795727|NZ_CP023587.1_3054334-3054352|NZ_CP023587.1_3054433-3054451|NZ_CP023587.1_3705246-3705264|NZ_CP023587.1_3737223-3737205|NZ_CP023587.1_3737847-3737829|NZ_CP023587.1_3738090-3738072|NZ_CP023587.1_3738223-3738205|NZ_CP023587.1_3802086-3802104|NZ_CP023587.1_3802269-3802287|NZ_CP023587.1_3802437-3802455|NZ_CP023587.1_3930257-3930275|NZ_CP023587.1_3931987-3932005|NZ_CP023587.1_3940485-3940503|NZ_CP023587.1_4031459-4031441|NZ_CP023587.1_4093981-4093999	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|89aa|up_3|NZ_CP023587.1_1207199_1207466_+,NA|61aa|down_3|NZ_CP023587.1_1215041_1215224_+,NA|35aa|down_4|NZ_CP023587.1_1215333_1215438_+	NA|465aa|up_9|NZ_CP023587.1_1201533_1202928_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023587.1_1203129_1203852_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023587.1_1203883_1205050_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023587.1_1205120_1205615_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023587.1_1205800_1206235_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023587.1_1206336_1207203_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023587.1_1207199_1207466_+	NA	NA|674aa|up_2|NZ_CP023587.1_1207452_1209474_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023587.1_1209572_1210301_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023587.1_1210411_1211200_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023587.1_1213856_1214177_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023587.1_1214329_1214764_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP023587.1_1214862_1215030_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023587.1_1215041_1215224_+	NA	NA|35aa|down_4|NZ_CP023587.1_1215333_1215438_+	NA	NA|152aa|down_5|NZ_CP023587.1_1215415_1215871_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023587.1_1216285_1218847_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023587.1_1219064_1220003_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023587.1_1220390_1221671_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023587.1_1221774_1222602_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	6	1571996-1573068	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|106aa|up_7|NZ_CP023587.1_1563759_1564077_+,NA	NA|103aa|up_9|NZ_CP023587.1_1561274_1561583_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023587.1_1561579_1563199_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023587.1_1563759_1564077_+	NA	NA|209aa|up_6|NZ_CP023587.1_1564211_1564838_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023587.1_1564903_1565236_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023587.1_1565251_1566508_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023587.1_1566635_1567847_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023587.1_1567919_1569398_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023587.1_1569394_1570780_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023587.1_1570857_1571892_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023587.1_1573922_1574324_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023587.1_1574320_1574578_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023587.1_1574660_1575620_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023587.1_1575644_1576607_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023587.1_1576740_1577343_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023587.1_1577423_1579391_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023587.1_1579408_1580233_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023587.1_1580401_1580884_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023587.1_1580955_1581780_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023587.1_1581976_1582915_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	7	1636426-1636652	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|38aa|up_8|NZ_CP023587.1_1622934_1623048_-,NA|137aa|up_7|NZ_CP023587.1_1623097_1623508_-,NA|288aa|down_2|NZ_CP023587.1_1640490_1641354_+	NA|162aa|up_9|NZ_CP023587.1_1622017_1622503_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP023587.1_1622934_1623048_-	NA	NA|137aa|up_7|NZ_CP023587.1_1623097_1623508_-	NA	NA|248aa|up_6|NZ_CP023587.1_1623524_1624268_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP023587.1_1624264_1625176_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP023587.1_1625228_1626773_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP023587.1_1626769_1627891_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP023587.1_1627907_1630010_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP023587.1_1630448_1634438_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP023587.1_1634839_1635766_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP023587.1_1638191_1639457_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP023587.1_1639484_1640471_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP023587.1_1640490_1641354_+	NA	NA|311aa|down_3|NZ_CP023587.1_1641303_1642236_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP023587.1_1642347_1643133_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP023587.1_1643129_1644071_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP023587.1_1644173_1645949_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP023587.1_1645996_1646803_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP023587.1_1646799_1649340_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP023587.1_1649336_1650530_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	8	2088089-2088343	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088170-2088187|2088170-2088187|2088260-2088277	NZ_CP023587.1_401063-401046|NZ_CP023587.1_607287-607270|NZ_CP023587.1_3449947-3449930	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|88aa|up_0|NZ_CP023587.1_2087448_2087712_-,NA	NA|165aa|up_9|NZ_CP023587.1_2073742_2074237_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023587.1_2074640_2075318_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023587.1_2075676_2078502_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023587.1_2078728_2079589_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023587.1_2079629_2080496_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023587.1_2080500_2082387_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023587.1_2082402_2084436_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023587.1_2084555_2086781_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023587.1_2087056_2087452_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023587.1_2087448_2087712_-	NA	NA|346aa|down_0|NZ_CP023587.1_2089480_2090518_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023587.1_2090517_2091885_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023587.1_2092058_2093495_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023587.1_2093530_2094982_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023587.1_2095011_2095962_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023587.1_2095976_2096393_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023587.1_2096670_2097093_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023587.1_2097141_2097444_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023587.1_2097440_2097755_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023587.1_2097754_2099488_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	9	2168619-2168838	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|136aa|up_3|NZ_CP023587.1_2159725_2160133_-,NA|127aa|down_5|NZ_CP023587.1_2176354_2176735_-	NA|741aa|up_9|NZ_CP023587.1_2153693_2155916_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023587.1_2155953_2156397_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023587.1_2156510_2157104_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023587.1_2157186_2157792_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023587.1_2157891_2158896_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023587.1_2158995_2159748_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023587.1_2159725_2160133_-	NA	NA|368aa|up_2|NZ_CP023587.1_2160267_2161371_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023587.1_2161370_2162567_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023587.1_2162736_2167116_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023587.1_2170865_2171330_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023587.1_2171427_2172291_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023587.1_2172328_2173600_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023587.1_2173871_2174987_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023587.1_2174977_2176318_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023587.1_2176354_2176735_-	NA	NA|621aa|down_6|NZ_CP023587.1_2176891_2178754_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023587.1_2178761_2179241_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023587.1_2179477_2180251_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023587.1_2180254_2181022_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	10	3118925-3120279	2,7,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type III-D,Type III-C,Type III-A,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	16,17,18	18	TypeIII-D,TypeIII-C,TypeIII-A,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|85aa|up_8|NZ_CP023587.1_3112204_3112459_-,NA|135aa|up_7|NZ_CP023587.1_3112606_3113011_+,NA|64aa|up_6|NZ_CP023587.1_3113007_3113199_+,NA|86aa|up_4|NZ_CP023587.1_3114785_3115043_+,NA|104aa|up_3|NZ_CP023587.1_3115147_3115459_+,NA|203aa|up_2|NZ_CP023587.1_3115878_3116487_+,NA	NA|92aa|up_9|NZ_CP023587.1_3111753_3112029_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023587.1_3112204_3112459_-	NA	NA|135aa|up_7|NZ_CP023587.1_3112606_3113011_+	NA	NA|64aa|up_6|NZ_CP023587.1_3113007_3113199_+	NA	NA|385aa|up_5|NZ_CP023587.1_3113397_3114552_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023587.1_3114785_3115043_+	NA	NA|104aa|up_3|NZ_CP023587.1_3115147_3115459_+	NA	NA|203aa|up_2|NZ_CP023587.1_3115878_3116487_+	NA	NA|470aa|up_1|NZ_CP023587.1_3116557_3117967_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023587.1_3117963_3118776_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023587.1_3120305_3121567_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023587.1_3123364_3123706_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023587.1_3123706_3124723_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023587.1_3124735_3125884_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023587.1_3125979_3127107_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023587.1_3127103_3128012_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023587.1_3127992_3128703_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023587.1_3128712_3129087_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023587.1_3129083_3131522_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023587.1_3131518_3132241_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	11	3121602-3123316	8,4,3	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type III-D,Type III-C,Type III-A,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-D,TypeIII-C,TypeIII-A,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|85aa|up_9|NZ_CP023587.1_3112204_3112459_-,NA|135aa|up_8|NZ_CP023587.1_3112606_3113011_+,NA|64aa|up_7|NZ_CP023587.1_3113007_3113199_+,NA|86aa|up_5|NZ_CP023587.1_3114785_3115043_+,NA|104aa|up_4|NZ_CP023587.1_3115147_3115459_+,NA|203aa|up_3|NZ_CP023587.1_3115878_3116487_+,NA	NA|85aa|up_9|NZ_CP023587.1_3112204_3112459_-	NA	NA|135aa|up_8|NZ_CP023587.1_3112606_3113011_+	NA	NA|64aa|up_7|NZ_CP023587.1_3113007_3113199_+	NA	NA|385aa|up_6|NZ_CP023587.1_3113397_3114552_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023587.1_3114785_3115043_+	NA	NA|104aa|up_4|NZ_CP023587.1_3115147_3115459_+	NA	NA|203aa|up_3|NZ_CP023587.1_3115878_3116487_+	NA	NA|470aa|up_2|NZ_CP023587.1_3116557_3117967_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023587.1_3117963_3118776_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023587.1_3120305_3121567_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023587.1_3123364_3123706_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023587.1_3123706_3124723_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023587.1_3124735_3125884_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023587.1_3125979_3127107_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023587.1_3127103_3128012_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023587.1_3127992_3128703_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023587.1_3128712_3129087_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023587.1_3129083_3131522_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023587.1_3131518_3132241_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023587.1_3132640_3133186_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	12	3740417-3740958	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|96aa|down_4|NZ_CP023587.1_3755059_3755347_-,NA|87aa|down_9|NZ_CP023587.1_3768467_3768728_-	NA|282aa|up_9|NZ_CP023587.1_3719668_3720514_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023587.1_3720988_3721429_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023587.1_3721462_3722332_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023587.1_3722352_3723363_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023587.1_3723647_3724280_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023587.1_3724346_3725576_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023587.1_3725858_3727208_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023587.1_3727219_3728359_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023587.1_3728355_3729087_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023587.1_3729095_3736667_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023587.1_3742929_3743187_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023587.1_3743442_3752916_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023587.1_3753541_3753988_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023587.1_3754024_3754765_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023587.1_3755059_3755347_-	NA	NA|3717aa|down_5|NZ_CP023587.1_3755683_3766834_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023587.1_3767077_3767872_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023587.1_3767953_3768325_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023587.1_3768222_3768441_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023587.1_3768467_3768728_-	NA
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	13	3948092-3949690	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CANCGGCGGCACCGGCGGCANCGGCGGCANCGGCGG	36	1	5	3948683-3948718|3948683-3948718|3948683-3948718|3948683-3948718|3948683-3948718	NZ_CP023587.1_3946799-3946834|NZ_CP023587.1_3947141-3947176|NZ_CP023587.1_3947732-3947767|NZ_CP023587.1_3948083-3948118|NZ_CP023587.1_3932542-3932577	NA	18	18	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|280aa|down_2|NZ_CP023587.1_3953158_3953998_+	NA|64aa|up_9|NZ_CP023587.1_3921793_3921985_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_8|NZ_CP023587.1_3922199_3923402_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_7|NZ_CP023587.1_3923426_3924548_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_6|NZ_CP023587.1_3924618_3926127_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1385aa|up_5|NZ_CP023587.1_3926297_3930452_+	pfam00934, PE, PE family	NA|1899aa|up_4|NZ_CP023587.1_3930742_3936439_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP023587.1_3936605_3938153_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP023587.1_3938149_3938986_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1782aa|up_1|NZ_CP023587.1_3939345_3944691_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP023587.1_3944819_3945476_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023587.1_3950551_3952198_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023587.1_3952271_3953063_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023587.1_3953158_3953998_+	NA	NA|399aa|down_3|NZ_CP023587.1_3954052_3955249_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023587.1_3955277_3955988_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023587.1_3956052_3957096_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023587.1_3957248_3958160_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023587.1_3958175_3959240_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023587.1_3959256_3960441_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023587.1_3960482_3961514_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002447155.1_ASM244715v1	NZ_CP023587	Mycobacterium tuberculosis strain ME1473 chromosome, complete genome	14	4110398-4110486	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|257aa|up_8|NZ_CP023587.1_4100984_4101755_-,NA|119aa|up_3|NZ_CP023587.1_4106889_4107246_+,NA|52aa|up_2|NZ_CP023587.1_4107345_4107501_+,NA|233aa|up_0|NZ_CP023587.1_4109502_4110201_-,NA|126aa|down_6|NZ_CP023587.1_4115721_4116099_+	NA|288aa|up_9|NZ_CP023587.1_4099366_4100230_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023587.1_4100984_4101755_-	NA	NA|549aa|up_7|NZ_CP023587.1_4101751_4103398_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023587.1_4103394_4104258_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023587.1_4104250_4105177_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023587.1_4105178_4106804_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023587.1_4106889_4107246_+	NA	NA|52aa|up_2|NZ_CP023587.1_4107345_4107501_+	NA	NA|652aa|up_1|NZ_CP023587.1_4107511_4109467_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023587.1_4109502_4110201_-	NA	NA|173aa|down_0|NZ_CP023587.1_4110546_4111065_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023587.1_4111065_4112049_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023587.1_4112041_4113235_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023587.1_4113240_4114062_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023587.1_4114193_4114877_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023587.1_4114876_4115614_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023587.1_4115721_4116099_+	NA	NA|225aa|down_7|NZ_CP023587.1_4116197_4116872_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023587.1_4116977_4117772_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023587.1_4117778_4118234_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
