assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	1	335894-336862	1	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGCNCCGCCGNNGCCG	21	1	3	336734-336757|336734-336757|336734-336757	NZ_AP018036.1_1215155-1215132|NZ_AP018036.1_2422585-2422608|NZ_AP018036.1_2685060-2685037	NA	11	11	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_AP018036.1_331416_331599_-,NA	NA|561aa|up_9|NZ_AP018036.1_322823_324506_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_AP018036.1_324522_326718_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_AP018036.1_326831_327965_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_AP018036.1_327961_328582_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_AP018036.1_328678_329260_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_AP018036.1_329189_329915_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_AP018036.1_330004_330925_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_AP018036.1_330964_331393_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_AP018036.1_331416_331599_-	NA	NA|872aa|up_0|NZ_AP018036.1_331693_334309_-	pfam00934, PE, PE family	NA|537aa|down_0|NZ_AP018036.1_337520_339131_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_AP018036.1_339154_340063_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_AP018036.1_340286_342182_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_AP018036.1_342178_343795_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_AP018036.1_343791_347784_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_AP018036.1_347780_348089_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_AP018036.1_348091_349633_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_AP018036.1_349681_349975_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_AP018036.1_350004_350295_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_AP018036.1_350305_351193_+	pfam14011, ESX-1_EspG, EspG family
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	2	364620-365318	1	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	364908-364949|364983-365015	NZ_AP018036.1_372924-372965|NZ_AP018036.1_371739-371771	NA	10	10	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_AP018036.1_361632_361935_+,NA|161aa|down_1|NZ_AP018036.1_374713_375196_-,NA|410aa|down_5|NZ_AP018036.1_377312_378542_+,NA|129aa|down_7|NZ_AP018036.1_380630_381017_+	NA|262aa|up_9|NZ_AP018036.1_356327_357113_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_AP018036.1_357101_357905_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_AP018036.1_357914_359312_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_AP018036.1_359490_361266_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_AP018036.1_361408_361636_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_AP018036.1_361632_361935_+	NA	NA|74aa|up_3|NZ_AP018036.1_361982_362204_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_AP018036.1_362200_362626_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_AP018036.1_362761_363394_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_AP018036.1_363390_364299_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_AP018036.1_374054_374726_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_AP018036.1_374713_375196_-	NA	NA|239aa|down_2|NZ_AP018036.1_375253_375970_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_AP018036.1_376071_376728_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_AP018036.1_376797_377289_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_AP018036.1_377312_378542_+	NA	NA|621aa|down_6|NZ_AP018036.1_378696_380559_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_AP018036.1_380630_381017_+	NA	NA|212aa|down_8|NZ_AP018036.1_381019_381655_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_AP018036.1_381742_382627_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	3	690152-690228	2	CRISPRCasFinder	no	c2c9_V-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|136aa|up_9|NZ_AP018036.1_676048_676456_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_AP018036.1_676515_677202_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_AP018036.1_677355_679989_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_AP018036.1_680011_682399_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_AP018036.1_682535_683258_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_AP018036.1_683254_684052_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_AP018036.1_684053_684941_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_AP018036.1_684946_686161_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|344aa|up_1|NZ_AP018036.1_686157_687189_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|482aa|up_0|NZ_AP018036.1_687185_688631_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_AP018036.1_691363_692914_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_AP018036.1_692965_693358_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_AP018036.1_693354_693612_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_AP018036.1_693794_695030_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_AP018036.1_695280_695694_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_AP018036.1_695690_695927_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_AP018036.1_696030_696537_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_AP018036.1_696650_697121_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_AP018036.1_697164_697926_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_AP018036.1_697982_698294_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	4	1573197-1574269	3	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1573397-1573418	NZ_AP018036.1_1210248-1210227	NA	15	15	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|191aa|up_7|NZ_AP018036.1_1564705_1565278_+,NA	NA|103aa|up_9|NZ_AP018036.1_1562475_1562784_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_AP018036.1_1562780_1564400_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|191aa|up_7|NZ_AP018036.1_1564705_1565278_+	NA	NA|209aa|up_6|NZ_AP018036.1_1565412_1566039_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_AP018036.1_1566104_1566437_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_AP018036.1_1566452_1567709_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_AP018036.1_1567836_1569048_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_AP018036.1_1569120_1570599_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_AP018036.1_1570595_1571981_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_AP018036.1_1572058_1573093_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_AP018036.1_1575123_1575525_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_AP018036.1_1575521_1575779_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_AP018036.1_1575861_1576821_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_AP018036.1_1576845_1577808_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_AP018036.1_1577941_1578544_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_AP018036.1_1578624_1580592_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_AP018036.1_1580609_1581434_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_AP018036.1_1581602_1582085_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_AP018036.1_1582156_1582981_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_AP018036.1_1583177_1584116_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	5	1638031-1638257	1	PILER-CR	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_7|NZ_AP018036.1_1624138_1624252_-,NA|137aa|up_6|NZ_AP018036.1_1624301_1624712_-,NA|288aa|down_2|NZ_AP018036.1_1642083_1642947_+	NA|767aa|up_9|NZ_AP018036.1_1620805_1623106_+	TIGR00509, Trimethylamine-N-oxide_reductase_1, molybdopterin guanine dinucleotide-containing S/N-oxide reductases	NA|162aa|up_8|NZ_AP018036.1_1623221_1623707_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_7|NZ_AP018036.1_1624138_1624252_-	NA	NA|137aa|up_6|NZ_AP018036.1_1624301_1624712_-	NA	NA|248aa|up_5|NZ_AP018036.1_1624728_1625472_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|305aa|up_4|NZ_AP018036.1_1625468_1626383_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_3|NZ_AP018036.1_1626435_1627980_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_2|NZ_AP018036.1_1627976_1629098_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_1|NZ_AP018036.1_1629114_1631217_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|309aa|up_0|NZ_AP018036.1_1636252_1637179_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_AP018036.1_1639784_1641050_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_AP018036.1_1641077_1642064_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_AP018036.1_1642083_1642947_+	NA	NA|311aa|down_3|NZ_AP018036.1_1642896_1643829_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_AP018036.1_1643940_1644726_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_AP018036.1_1644722_1645664_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_AP018036.1_1645819_1647595_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_AP018036.1_1647642_1648449_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_AP018036.1_1648445_1650986_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_AP018036.1_1650982_1652176_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	6	2071818-2072072	2	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2071899-2071916|2071899-2071916|2071989-2072006	NZ_AP018036.1_399220-399203|NZ_AP018036.1_605487-605470|NZ_AP018036.1_3436856-3436839	NA	5	5	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_AP018036.1_2071177_2071441_-,NA	NA|165aa|up_9|NZ_AP018036.1_2057527_2058022_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_AP018036.1_2058369_2059047_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_AP018036.1_2059405_2062231_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_AP018036.1_2062457_2063318_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_AP018036.1_2063358_2064225_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_AP018036.1_2064229_2066116_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_AP018036.1_2066131_2068165_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_AP018036.1_2068284_2070510_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_AP018036.1_2070785_2071181_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_AP018036.1_2071177_2071441_-	NA	NA|346aa|down_0|NZ_AP018036.1_2073209_2074247_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_AP018036.1_2074246_2075614_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|480aa|down_2|NZ_AP018036.1_2075787_2077227_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_AP018036.1_2077259_2078711_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_AP018036.1_2078740_2079691_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_AP018036.1_2079705_2080122_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_AP018036.1_2080399_2080822_+	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|101aa|down_7|NZ_AP018036.1_2080870_2081173_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_AP018036.1_2081169_2081484_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_AP018036.1_2081483_2083217_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	7	2154890-2155109	4	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_AP018036.1_2143500_2143908_-,NA|127aa|down_5|NZ_AP018036.1_2162625_2163006_-	NA|155aa|up_9|NZ_AP018036.1_2136828_2137293_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_AP018036.1_2137468_2139691_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_AP018036.1_2139728_2140172_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_AP018036.1_2140285_2140879_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_AP018036.1_2140961_2141567_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_AP018036.1_2141666_2142671_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_AP018036.1_2142770_2143523_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_AP018036.1_2143500_2143908_-	NA	NA|767aa|up_1|NZ_AP018036.1_2144042_2146343_+	PLN02892, PLN02892, isocitrate lyase	NA|421aa|up_0|NZ_AP018036.1_2150466_2151728_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|155aa|down_0|NZ_AP018036.1_2157136_2157601_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_AP018036.1_2157698_2158562_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_AP018036.1_2158599_2159871_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_AP018036.1_2160142_2161258_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_AP018036.1_2161248_2162589_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_AP018036.1_2162625_2163006_-	NA	NA|621aa|down_6|NZ_AP018036.1_2163162_2165025_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_AP018036.1_2165032_2165512_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_AP018036.1_2165748_2166522_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_AP018036.1_2166525_2167293_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	8	3108125-3109272	2,5,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-A,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	12,14,15	15	TypeIII-B,TypeIII-A,TypeIII-D,TypeIII-C	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_AP018036.1_3101404_3101659_-,NA|135aa|up_7|NZ_AP018036.1_3101806_3102211_+,NA|64aa|up_6|NZ_AP018036.1_3102207_3102399_+,NA|86aa|up_4|NZ_AP018036.1_3103985_3104243_+,NA|104aa|up_3|NZ_AP018036.1_3104347_3104659_+,NA|203aa|up_2|NZ_AP018036.1_3105078_3105687_+,NA	NA|92aa|up_9|NZ_AP018036.1_3100953_3101229_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_AP018036.1_3101404_3101659_-	NA	NA|135aa|up_7|NZ_AP018036.1_3101806_3102211_+	NA	NA|64aa|up_6|NZ_AP018036.1_3102207_3102399_+	NA	NA|385aa|up_5|NZ_AP018036.1_3102597_3103752_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_AP018036.1_3103985_3104243_+	NA	NA|104aa|up_3|NZ_AP018036.1_3104347_3104659_+	NA	NA|203aa|up_2|NZ_AP018036.1_3105078_3105687_+	NA	NA|470aa|up_1|NZ_AP018036.1_3105757_3107167_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_AP018036.1_3107163_3107976_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_AP018036.1_3109303_3110565_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	csm3gr7|237aa|down_1|NZ_AP018036.1_3110928_3111639_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_2|NZ_AP018036.1_3111648_3112023_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_3|NZ_AP018036.1_3112019_3114458_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_4|NZ_AP018036.1_3114454_3115177_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_5|NZ_AP018036.1_3115576_3116122_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|295aa|down_6|NZ_AP018036.1_3116393_3117278_-	COG2253, COG2253, Uncharacterized conserved protein [Function unknown]	NA|296aa|down_7|NZ_AP018036.1_3117280_3118168_-	pfam09407, AbiEi_1, AbiEi antitoxin C-terminal domain	NA|182aa|down_8|NZ_AP018036.1_3118472_3119018_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|90aa|down_9|NZ_AP018036.1_3119014_3119284_-	COG5552, COG5552, Uncharacterized conserved protein [Function unknown]
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	9	3652878-3652996	6	CRISPRCasFinder	no	cas3	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Unclear	GCCCCTGTGAGTCGAGTGAGCGGAACGAAC	30	1	1	3652908-3652966	NZ_AP018036.1_3652971-3653029	NA	1	1	Unclear	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|138aa|down_6|NZ_AP018036.1_3658629_3659043_-,NA|126aa|down_7|NZ_AP018036.1_3659077_3659455_-	NA|719aa|up_9|NZ_AP018036.1_3639704_3641861_+	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism]	NA|223aa|up_8|NZ_AP018036.1_3641857_3642526_-	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]	NA|395aa|up_7|NZ_AP018036.1_3642626_3643811_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|765aa|up_6|NZ_AP018036.1_3643815_3646110_+	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]	NA|390aa|up_5|NZ_AP018036.1_3646098_3647268_-	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|175aa|up_4|NZ_AP018036.1_3647292_3647817_-	PLN02948, PLN02948, phosphoribosylaminoimidazole carboxylase	NA|430aa|up_3|NZ_AP018036.1_3647813_3649103_-	TIGR01161, N5-carboxyaminoimidazole_ribonucleotide_synthase, phosphoribosylaminoimidazole carboxylase, PurK protein	NA|273aa|up_2|NZ_AP018036.1_3649056_3649875_+	COG2246, COG2246, Predicted membrane protein [Function unknown]	NA|173aa|up_1|NZ_AP018036.1_3649829_3650348_-	pfam03703, bPH_2, Bacterial PH domain	NA|267aa|up_0|NZ_AP018036.1_3650390_3651191_-	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]	NA|223aa|down_0|NZ_AP018036.1_3653262_3653931_+	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|298aa|down_1|NZ_AP018036.1_3653971_3654865_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|144aa|down_2|NZ_AP018036.1_3654861_3655293_+	COG2166, sufE, Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]	NA|601aa|down_3|NZ_AP018036.1_3655400_3657203_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|262aa|down_4|NZ_AP018036.1_3657212_3657998_-	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed	NA|146aa|down_5|NZ_AP018036.1_3657994_3658432_-	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]	NA|138aa|down_6|NZ_AP018036.1_3658629_3659043_-	NA	NA|126aa|down_7|NZ_AP018036.1_3659077_3659455_-	NA	NA|450aa|down_8|NZ_AP018036.1_3659488_3660838_-	PRK08297, PRK08297, L-lysine aminotransferase; Provisional	NA|151aa|down_9|NZ_AP018036.1_3660888_3661341_-	smart00344, HTH_ASNC, helix_turn_helix ASNC type
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	10	3738262-3738838	4	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGTTGCCNCCGNNGCCGCCG	25	0	0	NA	NA	NA	7	7	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_AP018036.1_3753070_3753358_-,NA|87aa|down_8|NZ_AP018036.1_3766477_3766738_-	NA|290aa|up_9|NZ_AP018036.1_3714576_3715446_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_8|NZ_AP018036.1_3715466_3716477_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|215aa|up_7|NZ_AP018036.1_3716749_3717394_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|412aa|up_6|NZ_AP018036.1_3717460_3718696_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|421aa|up_5|NZ_AP018036.1_3718694_3719956_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|450aa|up_4|NZ_AP018036.1_3720330_3721680_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_AP018036.1_3721691_3722831_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_AP018036.1_3722827_3723559_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|3655aa|up_1|NZ_AP018036.1_3723567_3734532_-	pfam00823, PPE, PPE family	NA|327aa|up_0|NZ_AP018036.1_3734580_3735561_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|86aa|down_0|NZ_AP018036.1_3740940_3741198_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_AP018036.1_3741453_3750927_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_AP018036.1_3751552_3751999_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_AP018036.1_3752035_3752776_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_AP018036.1_3753070_3753358_-	NA	NA|265aa|down_5|NZ_AP018036.1_3765087_3765882_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_6|NZ_AP018036.1_3765963_3766335_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_7|NZ_AP018036.1_3766232_3766451_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_8|NZ_AP018036.1_3766477_3766738_-	NA	NA|130aa|down_9|NZ_AP018036.1_3766852_3767242_+	pfam05305, DUF732, Protein of unknown function (DUF732)
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	11	3848119-3848208	7	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|77aa|up_7|NZ_AP018036.1_3840155_3840386_+,NA|121aa|up_6|NZ_AP018036.1_3840489_3840852_-,NA|73aa|up_2|NZ_AP018036.1_3846184_3846403_-,NA|121aa|down_0|NZ_AP018036.1_3849193_3849556_-,NA|52aa|down_2|NZ_AP018036.1_3851397_3851553_-,NA|52aa|down_3|NZ_AP018036.1_3851577_3851733_-,NA|238aa|down_6|NZ_AP018036.1_3855768_3856482_-	NA|169aa|up_9|NZ_AP018036.1_3838466_3838973_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|409aa|up_8|NZ_AP018036.1_3838969_3840196_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_7|NZ_AP018036.1_3840155_3840386_+	NA	NA|121aa|up_6|NZ_AP018036.1_3840489_3840852_-	NA	NA|177aa|up_5|NZ_AP018036.1_3841810_3842341_+	pfam00823, PPE, PPE family	NA|252aa|up_4|NZ_AP018036.1_3842658_3843414_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|421aa|up_3|NZ_AP018036.1_3843497_3844759_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|73aa|up_2|NZ_AP018036.1_3846184_3846403_-	NA	NA|100aa|up_1|NZ_AP018036.1_3846897_3847197_+	pfam00934, PE, PE family	NA|181aa|up_0|NZ_AP018036.1_3847282_3847825_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_AP018036.1_3849193_3849556_-	NA	NA|179aa|down_1|NZ_AP018036.1_3849718_3850255_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_AP018036.1_3851397_3851553_-	NA	NA|52aa|down_3|NZ_AP018036.1_3851577_3851733_-	NA	NA|461aa|down_4|NZ_AP018036.1_3852925_3854308_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|474aa|down_5|NZ_AP018036.1_3854345_3855767_-	pfam01256, Carb_kinase, Carbohydrate kinase	NA|238aa|down_6|NZ_AP018036.1_3855768_3856482_-	NA	NA|285aa|down_7|NZ_AP018036.1_3856492_3857347_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_8|NZ_AP018036.1_3857568_3859443_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_9|NZ_AP018036.1_3859464_3859941_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	12	3933451-3934395	5	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGNNNCGGCGGCNCCGGCGGC	24	0	0	NA	NA	NA	12	12	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_5|NZ_AP018036.1_3954457_3955297_+	NA|351aa|up_9|NZ_AP018036.1_3918197_3919250_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|401aa|up_8|NZ_AP018036.1_3919249_3920452_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|281aa|up_7|NZ_AP018036.1_3920471_3921314_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_6|NZ_AP018036.1_3921348_3922113_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_5|NZ_AP018036.1_3922338_3923292_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_4|NZ_AP018036.1_3923316_3923508_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_3|NZ_AP018036.1_3923722_3924925_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_2|NZ_AP018036.1_3924949_3926071_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_1|NZ_AP018036.1_3926141_3927650_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1384aa|up_0|NZ_AP018036.1_3927820_3931972_+	pfam00934, PE, PE family	NA|516aa|down_0|NZ_AP018036.1_3937174_3938722_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|down_1|NZ_AP018036.1_3938718_3939555_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|down_2|NZ_AP018036.1_3946548_3947205_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_3|NZ_AP018036.1_3951850_3953497_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_4|NZ_AP018036.1_3953570_3954362_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_5|NZ_AP018036.1_3954457_3955297_+	NA	NA|399aa|down_6|NZ_AP018036.1_3955351_3956548_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_7|NZ_AP018036.1_3956576_3957287_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_8|NZ_AP018036.1_3957351_3958395_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_9|NZ_AP018036.1_3958547_3959459_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	13	3949385-3951143	6	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CNNCGGCGGNNCCGGCGGCNNNGGCGGNNNCGGCGGC	37	2	7	3949986-3950020|3949986-3950020|3949986-3950020|3949986-3950020|3950874-3950899|3950874-3950899|3950874-3950899	NZ_AP018036.1_3948480-3948514|NZ_AP018036.1_3948867-3948901|NZ_AP018036.1_3949026-3949060|NZ_AP018036.1_3949377-3949411|NZ_AP018036.1_3942582-3942607|NZ_AP018036.1_3942918-3942943|NZ_AP018036.1_3943263-3943288	NA	23	23	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_AP018036.1_3954457_3955297_+	NA|318aa|up_9|NZ_AP018036.1_3922338_3923292_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_AP018036.1_3923316_3923508_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_AP018036.1_3923722_3924925_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_AP018036.1_3924949_3926071_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_AP018036.1_3926141_3927650_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1384aa|up_4|NZ_AP018036.1_3927820_3931972_+	pfam00934, PE, PE family	NA|1582aa|up_3|NZ_AP018036.1_3932262_3937008_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_AP018036.1_3937174_3938722_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_AP018036.1_3938718_3939555_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_AP018036.1_3946548_3947205_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_AP018036.1_3951850_3953497_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_AP018036.1_3953570_3954362_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_AP018036.1_3954457_3955297_+	NA	NA|399aa|down_3|NZ_AP018036.1_3955351_3956548_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_AP018036.1_3956576_3957287_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_AP018036.1_3957351_3958395_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_AP018036.1_3958547_3959459_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_AP018036.1_3959474_3960539_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_AP018036.1_3960555_3961740_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_AP018036.1_3961781_3962813_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002357975.1_ASM235797v1	NZ_AP018036	Mycobacterium tuberculosis strain HN-506	14	4112054-4112142	8	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_6|NZ_AP018036.1_4102640_4103411_-,NA|233aa|up_0|NZ_AP018036.1_4111158_4111857_-,NA|126aa|down_6|NZ_AP018036.1_4117377_4117755_+	NA|388aa|up_9|NZ_AP018036.1_4098311_4099475_-	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase	NA|351aa|up_8|NZ_AP018036.1_4099471_4100524_-	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein	NA|288aa|up_7|NZ_AP018036.1_4101022_4101886_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_6|NZ_AP018036.1_4102640_4103411_-	NA	NA|549aa|up_5|NZ_AP018036.1_4103407_4105054_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_4|NZ_AP018036.1_4105050_4105914_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_3|NZ_AP018036.1_4105906_4106833_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_2|NZ_AP018036.1_4106834_4108460_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|652aa|up_1|NZ_AP018036.1_4109167_4111123_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_AP018036.1_4111158_4111857_-	NA	NA|173aa|down_0|NZ_AP018036.1_4112202_4112721_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_AP018036.1_4112721_4113705_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_AP018036.1_4113697_4114891_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_AP018036.1_4114896_4115718_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_AP018036.1_4115849_4116533_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_AP018036.1_4116532_4117270_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_AP018036.1_4117377_4117755_+	NA	NA|225aa|down_7|NZ_AP018036.1_4117853_4118528_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_AP018036.1_4118633_4119428_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_AP018036.1_4119434_4119890_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
