assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	1	17777-17861	1	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TGTGTGTTAGCACTTTAAGCAAC	23	1	9	17800-17838|17800-17838|17800-17838|17800-17838|17800-17838|17800-17838|17800-17838|17800-17838|17800-17838	NZ_CP022524.1_12389-12427|NZ_CP022524.1_32031-32069|NZ_CP022524.1_131096-131134|NZ_CP022524.1_138046-138084|NZ_CP022524.1_154069-154107|NZ_CP022524.1_1114321-1114359|NZ_CP022524.1_3016243-3016205|NZ_CP022524.1_3802742-3802704|NZ_CP022524.1_3941461-3941423	NA	1	1	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|87aa|up_3|NZ_CP022524.1_8856_9117_+,NA|74aa|down_7|NZ_CP022524.1_28453_28675_+,NA|138aa|down_9|NZ_CP022524.1_39307_39721_+	NA|369aa|up_9|NZ_CP022524.1_1561_2668_+	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated	NA|69aa|up_8|NZ_CP022524.1_2804_3011_+	pfam13275, S4_2, S4 domain	NA|372aa|up_7|NZ_CP022524.1_3028_4144_+	PRK00064, recF, recombination protein F; Reviewed	NA|634aa|up_6|NZ_CP022524.1_4144_6046_+	PRK05644, gyrB, DNA gyrase subunit B; Validated	NA|809aa|up_5|NZ_CP022524.1_6065_8492_+	PRK05560, PRK05560, DNA gyrase subunit A; Validated	NA|99aa|up_4|NZ_CP022524.1_8560_8857_+	pfam12732, YtxH, YtxH-like protein	NA|87aa|up_3|NZ_CP022524.1_8856_9117_+	NA	NA|104aa|up_2|NZ_CP022524.1_9134_9446_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|136aa|up_1|NZ_CP022524.1_9449_9857_+	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional	NA|258aa|up_0|NZ_CP022524.1_9856_10630_+	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily	NA|176aa|down_0|NZ_CP022524.1_21257_21785_+	COG1827, COG1827, Predicted small molecule binding protein (contains 3H domain) [General function prediction only]	NA|294aa|down_1|NZ_CP022524.1_21796_22678_+	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS	NA|424aa|down_2|NZ_CP022524.1_23136_24408_+	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional	NA|152aa|down_3|NZ_CP022524.1_24728_25184_+	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|546aa|down_4|NZ_CP022524.1_25654_27292_+	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated	NA|117aa|down_5|NZ_CP022524.1_27350_27701_+	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein	NA|200aa|down_6|NZ_CP022524.1_27713_28313_+	PRK00076, recR, recombination protein RecR; Reviewed	NA|74aa|down_7|NZ_CP022524.1_28453_28675_+	NA	NA|402aa|down_8|NZ_CP022524.1_28745_29951_-	cd17507, GT28_Beta-DGS-like, beta-diglucosyldiacylglycerol synthase and similar proteins	NA|138aa|down_9|NZ_CP022524.1_39307_39721_+	NA
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	2	146622-146700	2	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TGTTTATAATGTGGATAATATTTAA	25	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|40aa|down_2|NZ_CP022524.1_161245_161365_+,NA|226aa|down_5|NZ_CP022524.1_163545_164223_+	NA|278aa|up_9|NZ_CP022524.1_123644_124478_+	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase	NA|289aa|up_8|NZ_CP022524.1_124465_125332_+	PRK13637, cbiO, energy-coupling factor transporter ATPase	NA|268aa|up_7|NZ_CP022524.1_125325_126129_+	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]	NA|244aa|up_6|NZ_CP022524.1_126160_126892_+	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA	NA|144aa|up_5|NZ_CP022524.1_127011_127443_+	PRK09216, rplM, 50S ribosomal protein L13; Reviewed	NA|131aa|up_4|NZ_CP022524.1_127471_127864_+	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed	NA|235aa|up_3|NZ_CP022524.1_128370_129075_+	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD	NA|395aa|up_2|NZ_CP022524.1_141671_142856_-	PRK05764, PRK05764, aspartate aminotransferase; Provisional	NA|784aa|up_1|NZ_CP022524.1_143228_145580_+	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional	NA|180aa|up_0|NZ_CP022524.1_145601_146141_+	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein	NA|280aa|down_0|NZ_CP022524.1_159231_160071_+	COG1624, COG1624, Uncharacterized conserved protein [Function unknown]	NA|394aa|down_1|NZ_CP022524.1_160067_161249_+	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown]	NA|40aa|down_2|NZ_CP022524.1_161245_161365_+	NA	NA|301aa|down_3|NZ_CP022524.1_161552_162455_+	PRK05805, PRK05805, phosphate butyryltransferase; Validated	NA|360aa|down_4|NZ_CP022524.1_162476_163556_+	PRK03011, PRK03011, butyrate kinase; Provisional	NA|226aa|down_5|NZ_CP022524.1_163545_164223_+	NA	NA|72aa|down_6|NZ_CP022524.1_164265_164481_+	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion]	NA|360aa|down_7|NZ_CP022524.1_164509_165589_+	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated	NA|251aa|down_8|NZ_CP022524.1_165588_166341_+	cd03375, TPP_OGFOR, Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor	NA|186aa|down_9|NZ_CP022524.1_166341_166899_+	pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	3	627617-627709	3	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	ATAAAAAGATATATTTATTAAATTTG	26	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|254aa|down_0|NZ_CP022524.1_627854_628616_+	NA|279aa|up_9|NZ_CP022524.1_614837_615674_+	PRK01060, PRK01060, endonuclease IV; Provisional	NA|332aa|up_8|NZ_CP022524.1_615957_616953_+	cd19100, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein	NA|135aa|up_7|NZ_CP022524.1_617209_617614_-	pfam05866, RusA, Endodeoxyribonuclease RusA	NA|305aa|up_6|NZ_CP022524.1_618710_619625_+	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase	NA|746aa|up_5|NZ_CP022524.1_619730_621968_+	pfam13654, AAA_32, AAA domain	NA|206aa|up_4|NZ_CP022524.1_622599_623217_+	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|157aa|up_3|NZ_CP022524.1_623410_623881_+	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL	NA|283aa|up_2|NZ_CP022524.1_623916_624765_+	TIGR00762, DegV, EDD domain protein, DegV family	NA|335aa|up_1|NZ_CP022524.1_625256_626261_+	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea	NA|371aa|up_0|NZ_CP022524.1_626386_627499_+	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea	NA|254aa|down_0|NZ_CP022524.1_627854_628616_+	NA	NA|273aa|down_1|NZ_CP022524.1_628618_629437_+	pfam08812, YtxC, YtxC-like family	NA|201aa|down_2|NZ_CP022524.1_629616_630219_+	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown]	NA|640aa|down_3|NZ_CP022524.1_631080_633000_+	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed	NA|364aa|down_4|NZ_CP022524.1_633767_634859_+	pfam12784, PDDEXK_2, PD-(D/E)XK nuclease family transposase	NA|447aa|down_5|NZ_CP022524.1_635524_636865_+	cd16935, HATPase_AgrC-ComD-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing	NA|190aa|down_6|NZ_CP022524.1_637486_638056_-	COG2316, COG2316, Predicted hydrolase (HD superfamily) [General function prediction only]	NA|417aa|down_7|NZ_CP022524.1_638216_639467_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|196aa|down_8|NZ_CP022524.1_639757_640345_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|487aa|down_9|NZ_CP022524.1_640690_642151_+	cd07082, ALDH_F11_NP-GAPDH, NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	4	1307572-1307930	1,4,1	PILER-CR,CRISPRCasFinder,CRT	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	GTTTTATATTAACTAAGTGGTATGTAAAG,GTTTTATATTAACTAAGTGGTATGTAAAG,GTTTTATATTAACTAAGTGGTATGTAAAG	29,29,29	0	0	NA	NA	I-A:I-A:I-A	4,5,5	5	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|51aa|up_0|NZ_CP022524.1_1306765_1306918_+,NA|52aa|down_1|NZ_CP022524.1_1309151_1309307_+,NA|34aa|down_2|NZ_CP022524.1_1309331_1309433_+,NA|84aa|down_3|NZ_CP022524.1_1309552_1309804_+,NA|38aa|down_4|NZ_CP022524.1_1310123_1310237_+,NA|128aa|down_5|NZ_CP022524.1_1311013_1311397_-,NA|115aa|down_6|NZ_CP022524.1_1311523_1311868_+,NA|72aa|down_7|NZ_CP022524.1_1312050_1312266_+,NA|40aa|down_8|NZ_CP022524.1_1313071_1313191_-,NA|106aa|down_9|NZ_CP022524.1_1313250_1313568_-	NA|271aa|up_9|NZ_CP022524.1_1294681_1295494_+	cd09009, PNP-EcPNPII_like, purine nucleoside phosphorylases similar to human PNP and Escherichia coli PNP-II (XapA)	NA|447aa|up_8|NZ_CP022524.1_1295682_1297023_+	TIGR02644, Thymidine_phosphorylase, pyrimidine-nucleoside phosphorylase	NA|360aa|up_7|NZ_CP022524.1_1297235_1298315_+	pfam02618, YceG, YceG-like family	NA|225aa|up_6|NZ_CP022524.1_1298486_1299161_+	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only]	NA|416aa|up_5|NZ_CP022524.1_1299147_1300395_+	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]	NA|555aa|up_4|NZ_CP022524.1_1300466_1302131_+	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|506aa|up_3|NZ_CP022524.1_1302534_1304052_-	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain	NA|274aa|up_2|NZ_CP022524.1_1304176_1304998_-	sd00006, TPR, Tetratricopeptide repeat	NA|476aa|up_1|NZ_CP022524.1_1305188_1306616_+	NF033435, S-layer_Clost, S-layer protein SlpA	NA|51aa|up_0|NZ_CP022524.1_1306765_1306918_+	NA	NA|75aa|down_0|NZ_CP022524.1_1308216_1308441_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|52aa|down_1|NZ_CP022524.1_1309151_1309307_+	NA	NA|34aa|down_2|NZ_CP022524.1_1309331_1309433_+	NA	NA|84aa|down_3|NZ_CP022524.1_1309552_1309804_+	NA	NA|38aa|down_4|NZ_CP022524.1_1310123_1310237_+	NA	NA|128aa|down_5|NZ_CP022524.1_1311013_1311397_-	NA	NA|115aa|down_6|NZ_CP022524.1_1311523_1311868_+	NA	NA|72aa|down_7|NZ_CP022524.1_1312050_1312266_+	NA	NA|40aa|down_8|NZ_CP022524.1_1313071_1313191_-	NA	NA|106aa|down_9|NZ_CP022524.1_1313250_1313568_-	NA
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	5	1516045-1516405	2,5,2	PILER-CR,CRISPRCasFinder,CRT	no	DinG	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Type IV-A	GTTTTATATTAACTAAGTGGTATGTAAAT,GTTTTATATTAACTAAGTGGTATGTAAAT,GTTTTATATTAACTAAGTGGTATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	4,5,4	5	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|183aa|up_5|NZ_CP022524.1_1509019_1509568_-,NA|82aa|up_1|NZ_CP022524.1_1514540_1514786_-,NA|35aa|up_0|NZ_CP022524.1_1515410_1515515_+,NA|80aa|down_4|NZ_CP022524.1_1523528_1523768_+,NA|59aa|down_5|NZ_CP022524.1_1523955_1524132_-,NA|45aa|down_9|NZ_CP022524.1_1526758_1526893_+	NA|195aa|up_9|NZ_CP022524.1_1504217_1504802_-	pfam00882, Zn_dep_PLPC, Zinc dependent phospholipase C	NA|477aa|up_8|NZ_CP022524.1_1505001_1506432_-	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]	NA|315aa|up_7|NZ_CP022524.1_1506749_1507694_+	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter	NA|312aa|up_6|NZ_CP022524.1_1507965_1508901_-	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only]	NA|183aa|up_5|NZ_CP022524.1_1509019_1509568_-	NA	NA|143aa|up_4|NZ_CP022524.1_1509719_1510148_+	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ	NA|223aa|up_3|NZ_CP022524.1_1510214_1510883_+	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily	NA|452aa|up_2|NZ_CP022524.1_1511000_1512356_-	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA	NA|82aa|up_1|NZ_CP022524.1_1514540_1514786_-	NA	NA|35aa|up_0|NZ_CP022524.1_1515410_1515515_+	NA	NA|578aa|down_0|NZ_CP022524.1_1516730_1518464_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|278aa|down_1|NZ_CP022524.1_1518703_1519537_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|745aa|down_2|NZ_CP022524.1_1519567_1521802_-	cd01948, EAL, EAL domain	NA|270aa|down_3|NZ_CP022524.1_1522585_1523395_+	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators	NA|80aa|down_4|NZ_CP022524.1_1523528_1523768_+	NA	NA|59aa|down_5|NZ_CP022524.1_1523955_1524132_-	NA	NA|225aa|down_6|NZ_CP022524.1_1524636_1525311_-	COG1285, SapB, Uncharacterized membrane protein [Function unknown]	NA|185aa|down_7|NZ_CP022524.1_1525530_1526085_-	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases	NA|122aa|down_8|NZ_CP022524.1_1526162_1526528_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|45aa|down_9|NZ_CP022524.1_1526758_1526893_+	NA
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	6	1626664-1627753	3,6,3	PILER-CR,CRISPRCasFinder,CRT	no	cas14j	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Unclear	GTTTTATATTAACTATATGGAATGTAAAT,GTTTTATATTAACTATATGGAATGTAAAT,GTTTTATATTAACTATATGGAATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	15,16,16	16	TypeV	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|50aa|up_9|NZ_CP022524.1_1615489_1615639_+,NA|190aa|up_7|NZ_CP022524.1_1616553_1617123_+,NA|61aa|up_4|NZ_CP022524.1_1620072_1620255_-,NA|323aa|down_4|NZ_CP022524.1_1632675_1633644_+	NA|50aa|up_9|NZ_CP022524.1_1615489_1615639_+	NA	NA|300aa|up_8|NZ_CP022524.1_1615649_1616549_+	TIGR02163, Ferredoxin-type_protein_NapH_homolog, ferredoxin-type protein, NapH/MauN family	NA|190aa|up_7|NZ_CP022524.1_1616553_1617123_+	NA	NA|216aa|up_6|NZ_CP022524.1_1617289_1617937_-	pfam02589, LUD_dom, LUD domain	NA|305aa|up_5|NZ_CP022524.1_1618326_1619241_-	pfam11155, DUF2935, Domain of unknown function (DUF2935)	NA|61aa|up_4|NZ_CP022524.1_1620072_1620255_-	NA	NA|283aa|up_3|NZ_CP022524.1_1620665_1621514_-	PRK00380, panC, pantoate--beta-alanine ligase; Reviewed	NA|276aa|up_2|NZ_CP022524.1_1621532_1622360_-	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed	NA|308aa|up_1|NZ_CP022524.1_1622334_1623258_-	pfam10728, DUF2520, Domain of unknown function (DUF2520)	NA|698aa|up_0|NZ_CP022524.1_1623911_1626005_+	cd01948, EAL, EAL domain	NA|273aa|down_0|NZ_CP022524.1_1628411_1629230_+	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator	NA|707aa|down_1|NZ_CP022524.1_1629362_1631483_-	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism]	NA|76aa|down_2|NZ_CP022524.1_1631508_1631736_-	pfam04023, FeoA, FeoA domain	NA|147aa|down_3|NZ_CP022524.1_1632062_1632503_-	COG2153, ElaA, Predicted acyltransferase [General function prediction only]	NA|323aa|down_4|NZ_CP022524.1_1632675_1633644_+	NA	NA|403aa|down_5|NZ_CP022524.1_1634120_1635329_+	PRK13354, PRK13354, tyrosyl-tRNA synthetase; Provisional	NA|294aa|down_6|NZ_CP022524.1_1635389_1636271_-	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins	NA|305aa|down_7|NZ_CP022524.1_1636686_1637601_+	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]	NA|182aa|down_8|NZ_CP022524.1_1637823_1638369_+	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain	NA|383aa|down_9|NZ_CP022524.1_1638468_1639617_+	COG2006, COG2006, Uncharacterized conserved protein [Function unknown]
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	7	1803151-1804366	4,7,4	PILER-CR,CRISPRCasFinder,CRT	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	GTTTTATATTAACTAAGTGGTATGTAAAT,GTTTTATATTAACTAAGTGGTATGTAAAT,GTTTTATATTAACTAAGTGGTATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	14,18,18	18	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|96aa|down_0|NZ_CP022524.1_1804774_1805062_+,NA|59aa|down_5|NZ_CP022524.1_1811451_1811628_-,NA|341aa|down_6|NZ_CP022524.1_1812202_1813225_+,NA|258aa|down_8|NZ_CP022524.1_1814131_1814905_+	NA|200aa|up_9|NZ_CP022524.1_1786678_1787278_-	COG4110, COG4110, Uncharacterized protein involved in stress response [General function prediction only]	NA|266aa|up_8|NZ_CP022524.1_1787380_1788178_-	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]	NA|329aa|up_7|NZ_CP022524.1_1788488_1789475_-	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase	NA|577aa|up_6|NZ_CP022524.1_1789958_1791689_+	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion]	NA|172aa|up_5|NZ_CP022524.1_1792213_1792729_+	pfam13787, HXXEE, Protein of unknown function with HXXEE motif	NA|825aa|up_4|NZ_CP022524.1_1793534_1796009_+	PRK00451, PRK00451, aminomethyl-transferring glycine dehydrogenase subunit GcvPA	NA|486aa|up_3|NZ_CP022524.1_1796008_1797466_+	PRK04366, PRK04366, aminomethyl-transferring glycine dehydrogenase subunit GcvPB	NA|786aa|up_2|NZ_CP022524.1_1797888_1800246_+	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7	NA|106aa|up_1|NZ_CP022524.1_1800331_1800649_-	pfam06865, DUF1255, Protein of unknown function (DUF1255)	NA|424aa|up_0|NZ_CP022524.1_1801232_1802504_-	cd01303, GDEase, Guanine deaminase (GDEase)	NA|96aa|down_0|NZ_CP022524.1_1804774_1805062_+	NA	NA|184aa|down_1|NZ_CP022524.1_1805600_1806152_-	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain	NA|321aa|down_2|NZ_CP022524.1_1806342_1807305_+	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase	NA|615aa|down_3|NZ_CP022524.1_1807598_1809443_+	cd08579, GDPD_memb_like, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases	NA|195aa|down_4|NZ_CP022524.1_1809764_1810349_+	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates	NA|59aa|down_5|NZ_CP022524.1_1811451_1811628_-	NA	NA|341aa|down_6|NZ_CP022524.1_1812202_1813225_+	NA	NA|296aa|down_7|NZ_CP022524.1_1813238_1814126_+	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component	NA|258aa|down_8|NZ_CP022524.1_1814131_1814905_+	NA	NA|242aa|down_9|NZ_CP022524.1_1815016_1815742_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	8	2122235-2122402	5	PILER-CR	no	csa3	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Type I-A	TATTTAGGTTTTATATCAACTATGTGGTATGTAAAGAG	38	0	0	NA	NA	I-A	2	2	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|59aa|up_5|NZ_CP022524.1_2117013_2117190_+,NA|133aa|up_3|NZ_CP022524.1_2118721_2119120_-,NA|59aa|up_1|NZ_CP022524.1_2121267_2121444_+,NA|55aa|down_2|NZ_CP022524.1_2123941_2124106_-,NA|17aa|down_6|NZ_CP022524.1_2126531_2126582_+,NA|45aa|down_7|NZ_CP022524.1_2126762_2126897_-	NA|204aa|up_9|NZ_CP022524.1_2111684_2112296_+	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|113aa|up_8|NZ_CP022524.1_2112593_2112932_+	pfam12650, DUF3784, Domain of unknown function (DUF3784)	NA|479aa|up_7|NZ_CP022524.1_2113338_2114775_-	PRK14328, PRK14328, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional	NA|491aa|up_6|NZ_CP022524.1_2115022_2116495_-	NF033435, S-layer_Clost, S-layer protein SlpA	NA|59aa|up_5|NZ_CP022524.1_2117013_2117190_+	NA	NA|184aa|up_4|NZ_CP022524.1_2117320_2117872_-	pfam17099, TrpP, Tryptophan transporter TrpP	NA|133aa|up_3|NZ_CP022524.1_2118721_2119120_-	NA	NA|162aa|up_2|NZ_CP022524.1_2119474_2119960_-	pfam08239, SH3_3, Bacterial SH3 domain	NA|59aa|up_1|NZ_CP022524.1_2121267_2121444_+	NA	NA|67aa|up_0|NZ_CP022524.1_2121669_2121870_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|61aa|down_0|NZ_CP022524.1_2122619_2122802_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|282aa|down_1|NZ_CP022524.1_2122872_2123718_+	pfam13026, DUF3887, Protein of unknown function (DUF3887)	NA|55aa|down_2|NZ_CP022524.1_2123941_2124106_-	NA	NA|111aa|down_3|NZ_CP022524.1_2124647_2124980_-	pfam02627, CMD, Carboxymuconolactone decarboxylase family	NA|214aa|down_4|NZ_CP022524.1_2125223_2125865_-	COG5658, COG5658, Predicted integral membrane protein [Function unknown]	csa3|99aa|down_5|NZ_CP022524.1_2125845_2126142_-	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors	NA|17aa|down_6|NZ_CP022524.1_2126531_2126582_+	NA	NA|45aa|down_7|NZ_CP022524.1_2126762_2126897_-	NA	NA|251aa|down_8|NZ_CP022524.1_2127107_2127860_-	PRK10621, PRK10621, hypothetical protein; Provisional	NA|552aa|down_9|NZ_CP022524.1_2127918_2129574_-	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	9	2173246-2174710	5,8,6	CRT,CRISPRCasFinder,PILER-CR	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	ATTTACATTCCATATAGTTAATATAAAACN,ATTTACATTCCATATAGTTAATATAAAAC,GTTTTATATTAACTATATGGAATGTAAAT	30,29,29	0	0	NA	NA	I-A:I-A:I-A	22,21,20	22	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|43aa|up_4|NZ_CP022524.1_2171120_2171249_+,NA|58aa|up_1|NZ_CP022524.1_2172520_2172694_+,NA|98aa|up_0|NZ_CP022524.1_2172850_2173144_-,NA|80aa|down_7|NZ_CP022524.1_2182919_2183159_-,NA|216aa|down_8|NZ_CP022524.1_2183329_2183977_-,NA|567aa|down_9|NZ_CP022524.1_2184116_2185817_-	NA|208aa|up_9|NZ_CP022524.1_2166180_2166804_-	pfam13189, Cytidylate_kin2, Cytidylate kinase-like family	NA|270aa|up_8|NZ_CP022524.1_2166895_2167705_+	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator	NA|121aa|up_7|NZ_CP022524.1_2168138_2168501_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|186aa|up_6|NZ_CP022524.1_2168850_2169408_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|233aa|up_5|NZ_CP022524.1_2169665_2170364_+	TIGR03502, lipase_Pla1_cef, extracellular lipase, Pla-1/cef family	NA|43aa|up_4|NZ_CP022524.1_2171120_2171249_+	NA	NA|156aa|up_3|NZ_CP022524.1_2171386_2171854_+	pfam11188, DUF2975, Protein of unknown function (DUF2975)	NA|72aa|up_2|NZ_CP022524.1_2171864_2172080_+	COG3655, COG3655, Predicted transcriptional regulator [Transcription]	NA|58aa|up_1|NZ_CP022524.1_2172520_2172694_+	NA	NA|98aa|up_0|NZ_CP022524.1_2172850_2173144_-	NA	NA|291aa|down_0|NZ_CP022524.1_2175540_2176413_-	COG1737, RpiR, Transcriptional regulators [Transcription]	NA|193aa|down_1|NZ_CP022524.1_2176806_2177385_-	pfam06962, rRNA_methylase, Putative rRNA methylase	NA|239aa|down_2|NZ_CP022524.1_2177442_2178159_-	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]	NA|362aa|down_3|NZ_CP022524.1_2178349_2179435_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|220aa|down_4|NZ_CP022524.1_2179589_2180249_-	pfam03154, Atrophin-1, Atrophin-1 family	NA|431aa|down_5|NZ_CP022524.1_2180465_2181758_-	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase	NA|398aa|down_6|NZ_CP022524.1_2181775_2182969_-	PRK06635, PRK06635, aspartate kinase; Reviewed	NA|80aa|down_7|NZ_CP022524.1_2182919_2183159_-	NA	NA|216aa|down_8|NZ_CP022524.1_2183329_2183977_-	NA	NA|567aa|down_9|NZ_CP022524.1_2184116_2185817_-	NA
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	10	2523783-2524862	9,6,7	CRISPRCasFinder,CRT,PILER-CR	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	ATTTACATTCCATATAGTTAATCTAAAAC,ATTTACATTCCATATAGTTAATCTAAAAC,GTTTTAGATTAACTATATGGAATGTAAAT	29,29,29	0	0	NA	NA	I-A:I-A:I-A	16,16,15	16	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|138aa|up_4|NZ_CP022524.1_2520036_2520450_+,NA|106aa|up_3|NZ_CP022524.1_2521046_2521364_+,NA|155aa|up_2|NZ_CP022524.1_2521499_2521964_+,NA|54aa|up_1|NZ_CP022524.1_2522292_2522454_-,NA|51aa|down_1|NZ_CP022524.1_2526245_2526398_-,NA|111aa|down_2|NZ_CP022524.1_2526671_2527004_-,NA|85aa|down_3|NZ_CP022524.1_2527030_2527285_-,NA|56aa|down_4|NZ_CP022524.1_2527425_2527593_-,NA|57aa|down_7|NZ_CP022524.1_2531060_2531231_+	NA|108aa|up_9|NZ_CP022524.1_2515137_2515461_+	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD)	NA|690aa|up_8|NZ_CP022524.1_2515666_2517736_-	cd16923, HATPase_VanS-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS	NA|231aa|up_7|NZ_CP022524.1_2517922_2518615_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|125aa|up_6|NZ_CP022524.1_2519226_2519601_-	pfam03965, Penicillinase_R, Penicillinase repressor	NA|78aa|up_5|NZ_CP022524.1_2519819_2520053_+	COG1476, COG1476, Predicted transcriptional regulators [Transcription]	NA|138aa|up_4|NZ_CP022524.1_2520036_2520450_+	NA	NA|106aa|up_3|NZ_CP022524.1_2521046_2521364_+	NA	NA|155aa|up_2|NZ_CP022524.1_2521499_2521964_+	NA	NA|54aa|up_1|NZ_CP022524.1_2522292_2522454_-	NA	NA|122aa|up_0|NZ_CP022524.1_2522953_2523319_-	smart01040, Bro-N, BRO family, N-terminal domain	NA|308aa|down_0|NZ_CP022524.1_2525128_2526052_-	pfam09851, SHOCT, Short C-terminal domain	NA|51aa|down_1|NZ_CP022524.1_2526245_2526398_-	NA	NA|111aa|down_2|NZ_CP022524.1_2526671_2527004_-	NA	NA|85aa|down_3|NZ_CP022524.1_2527030_2527285_-	NA	NA|56aa|down_4|NZ_CP022524.1_2527425_2527593_-	NA	NA|125aa|down_5|NZ_CP022524.1_2529003_2529378_-	pfam03965, Penicillinase_R, Penicillinase repressor	NA|163aa|down_6|NZ_CP022524.1_2530183_2530672_+	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]	NA|57aa|down_7|NZ_CP022524.1_2531060_2531231_+	NA	NA|63aa|down_8|NZ_CP022524.1_2531707_2531896_-	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|117aa|down_9|NZ_CP022524.1_2532057_2532408_+	pfam12676, DUF3796, Protein of unknown function (DUF3796)
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	11	2686541-2686698	8	PILER-CR	no	cas3,cas5,cas7,cas6	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Unclear	AGGTTTAAGATTAACTAAGTGGATTTCA	28	0	0	NA	NA	NA	2	2	Unclear	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|492aa|down_3|NZ_CP022524.1_2691120_2692596_-,NA|39aa|down_9|NZ_CP022524.1_2698671_2698788_-	NA|448aa|up_9|NZ_CP022524.1_2678997_2680341_-	pfam06898, YqfD, Putative stage IV sporulation protein YqfD	NA|81aa|up_8|NZ_CP022524.1_2680353_2680596_-	pfam07873, YabP, YabP family	NA|188aa|up_7|NZ_CP022524.1_2680802_2681366_-	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site	NA|166aa|up_6|NZ_CP022524.1_2681558_2682056_-	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family	NA|148aa|up_5|NZ_CP022524.1_2682166_2682610_-	pfam09424, YqeY, Yqey-like protein	NA|60aa|up_4|NZ_CP022524.1_2682639_2682819_-	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed	NA|117aa|up_3|NZ_CP022524.1_2682981_2683332_-	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides	NA|433aa|up_2|NZ_CP022524.1_2683374_2684673_-	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]	NA|253aa|up_1|NZ_CP022524.1_2684674_2685433_-	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional	NA|316aa|up_0|NZ_CP022524.1_2685451_2686399_-	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA)	cas3|803aa|down_0|NZ_CP022524.1_2686839_2689248_-	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3	cas5|266aa|down_1|NZ_CP022524.1_2689274_2690072_-	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|338aa|down_2|NZ_CP022524.1_2690087_2691101_-	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7	NA|492aa|down_3|NZ_CP022524.1_2691120_2692596_-	NA	cas6|246aa|down_4|NZ_CP022524.1_2692600_2693338_-	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6	NA|370aa|down_5|NZ_CP022524.1_2693595_2694705_+	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	NA|256aa|down_6|NZ_CP022524.1_2694734_2695502_+	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|458aa|down_7|NZ_CP022524.1_2695689_2697063_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|312aa|down_8|NZ_CP022524.1_2697098_2698034_-	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|39aa|down_9|NZ_CP022524.1_2698671_2698788_-	NA
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	12	2767971-2768529	9,7,10	PILER-CR,CRT,CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	GTTTTATATTAACTATATGGAATGTAAATT,AATTTACATTCCATATAGTTAATATAAAAC,ATTTACATTCCATATAGTTAATATAAAAC	30,30,29	0	0	NA	NA	I-A:I-A:I-A	8,8,8	8	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|53aa|down_0|NZ_CP022524.1_2768814_2768973_-	NA|240aa|up_9|NZ_CP022524.1_2755543_2756263_-	pfam01841, Transglut_core, Transglutaminase-like superfamily	NA|253aa|up_8|NZ_CP022524.1_2756309_2757068_-	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism]	NA|451aa|up_7|NZ_CP022524.1_2757198_2758551_-	cd05298, GH4_GlvA_pagL_like, Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases	NA|517aa|up_6|NZ_CP022524.1_2758647_2760198_-	TIGR02005, PTS-IIBC-alpha, PTS system, alpha-glucoside-specific IIBC component	NA|272aa|up_5|NZ_CP022524.1_2760248_2761064_-	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional	NA|161aa|up_4|NZ_CP022524.1_2761084_2761567_-	pfam00358, PTS_EIIA_1, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	NA|127aa|up_3|NZ_CP022524.1_2761850_2762231_-	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase	NA|406aa|up_2|NZ_CP022524.1_2762325_2763543_-	PRK08198, PRK08198, threonine dehydratase; Provisional	NA|543aa|up_1|NZ_CP022524.1_2764200_2765829_+	TIGR03801, For_A_Pyridoxal-5-_Phosphate, aspartate 4-decarboxylase	NA|332aa|up_0|NZ_CP022524.1_2765949_2766945_+	cd08964, L-asparaginase_II, Type II (periplasmic) bacterial L-asparaginase	NA|53aa|down_0|NZ_CP022524.1_2768814_2768973_-	NA	NA|457aa|down_1|NZ_CP022524.1_2769266_2770637_-	NF033435, S-layer_Clost, S-layer protein SlpA	NA|223aa|down_2|NZ_CP022524.1_2772452_2773121_-	pfam04892, VanZ, VanZ like family	NA|807aa|down_3|NZ_CP022524.1_2773973_2776394_-	PRK00390, leuS, leucyl-tRNA synthetase; Validated	NA|117aa|down_4|NZ_CP022524.1_2776747_2777098_-	pfam02410, RsfS, Ribosomal silencing factor during starvation	NA|191aa|down_5|NZ_CP022524.1_2777214_2777787_-	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism]	NA|230aa|down_6|NZ_CP022524.1_2777787_2778477_-	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase	NA|213aa|down_7|NZ_CP022524.1_2778752_2779391_+	PRK00117, recX, recombination regulator RecX; Reviewed	NA|668aa|down_8|NZ_CP022524.1_2779543_2781547_+	PLN02447, PLN02447, 1,4-alpha-glucan-branching enzyme	NA|214aa|down_9|NZ_CP022524.1_2781720_2782362_+	COG1309, AcrR, Transcriptional regulator [Transcription]
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	13	3003231-3003556	11	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TTACCATCTATTTGTTGCCATCCTGT	26	0	0	NA	NA	NA	5	5	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|107aa|down_2|NZ_CP022524.1_3006419_3006740_-,NA|664aa|down_3|NZ_CP022524.1_3006729_3008721_-,NA|458aa|down_7|NZ_CP022524.1_3019506_3020880_-	NA|218aa|up_9|NZ_CP022524.1_2988217_2988871_-	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]	NA|448aa|up_8|NZ_CP022524.1_2989373_2990717_+	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]	NA|455aa|up_7|NZ_CP022524.1_2990895_2992260_+	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases	NA|623aa|up_6|NZ_CP022524.1_2992437_2994306_-	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p	NA|406aa|up_5|NZ_CP022524.1_2994538_2995756_-	cd17396, MFS_YdiM_like, Inner membrane transport protein YdiM and similar proteins of the Major Facilitator Superfamily of transporters	NA|288aa|up_4|NZ_CP022524.1_2995955_2996819_-	PRK12548, PRK12548, shikimate dehydrogenase	NA|641aa|up_3|NZ_CP022524.1_2996900_2998823_-	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2	NA|283aa|up_2|NZ_CP022524.1_2998901_2999750_-	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|294aa|up_1|NZ_CP022524.1_3000162_3001044_+	cd08434, PBP2_GltC_like, The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold	NA|280aa|up_0|NZ_CP022524.1_3001251_3002091_-	cd01027, TOPRIM_RNase_M5_like, TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea	NA|338aa|down_0|NZ_CP022524.1_3004315_3005329_-	PLN02240, PLN02240, UDP-glucose 4-epimerase	NA|292aa|down_1|NZ_CP022524.1_3005352_3006228_-	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]	NA|107aa|down_2|NZ_CP022524.1_3006419_3006740_-	NA	NA|664aa|down_3|NZ_CP022524.1_3006729_3008721_-	NA	NA|848aa|down_4|NZ_CP022524.1_3008843_3011387_-	PTZ00121, PTZ00121, MAEBL; Provisional	NA|226aa|down_5|NZ_CP022524.1_3012130_3012808_+	cd05826, Sortase_B, Sortase domain found in class B sortases	NA|313aa|down_6|NZ_CP022524.1_3018196_3019135_+	cd10948, CE4_BsPdaA_like, Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs	NA|458aa|down_7|NZ_CP022524.1_3019506_3020880_-	NA	NA|441aa|down_8|NZ_CP022524.1_3021066_3022389_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|235aa|down_9|NZ_CP022524.1_3022381_3023086_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	14	3058012-3058319	12	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TTTCTTTTACAGCTTCTAAACATAT	25	0	0	NA	NA	NA	4	4	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|222aa|down_0|NZ_CP022524.1_3059612_3060278_+	NA|205aa|up_9|NZ_CP022524.1_3046172_3046787_-	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|150aa|up_8|NZ_CP022524.1_3046801_3047251_-	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional	NA|736aa|up_7|NZ_CP022524.1_3047275_3049483_-	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|171aa|up_6|NZ_CP022524.1_3049556_3050069_-	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional	NA|817aa|up_5|NZ_CP022524.1_3050081_3052532_-	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ	NA|555aa|up_4|NZ_CP022524.1_3052544_3054209_-	COG0661, AarF, Predicted unusual protein kinase [General function prediction only]	NA|166aa|up_3|NZ_CP022524.1_3054506_3055004_-	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|460aa|up_2|NZ_CP022524.1_3055032_3056412_-	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase	NA|49aa|up_1|NZ_CP022524.1_3056716_3056863_-	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|193aa|up_0|NZ_CP022524.1_3056892_3057471_-	pfam04647, AgrB, Accessory gene regulator B	NA|222aa|down_0|NZ_CP022524.1_3059612_3060278_+	NA	NA|901aa|down_1|NZ_CP022524.1_3060783_3063486_-	cd01948, EAL, EAL domain	NA|517aa|down_2|NZ_CP022524.1_3063511_3065062_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|571aa|down_3|NZ_CP022524.1_3065384_3067097_-	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]	NA|87aa|down_4|NZ_CP022524.1_3067450_3067711_-	pfam00381, PTS-HPr, PTS HPr component phosphorylation site	NA|404aa|down_5|NZ_CP022524.1_3067903_3069115_-	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli	NA|578aa|down_6|NZ_CP022524.1_3069346_3071080_-	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX	NA|133aa|down_7|NZ_CP022524.1_3071119_3071518_-	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|516aa|down_8|NZ_CP022524.1_3071520_3073068_-	cd01948, EAL, EAL domain	NA|302aa|down_9|NZ_CP022524.1_3073382_3074288_-	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	15	3058426-3058715	13	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TTTCTTTTACAGCTTCTAAACATAT	25	0	0	NA	NA	NA	4	4	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|222aa|down_0|NZ_CP022524.1_3059612_3060278_+	NA|205aa|up_9|NZ_CP022524.1_3046172_3046787_-	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|150aa|up_8|NZ_CP022524.1_3046801_3047251_-	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional	NA|736aa|up_7|NZ_CP022524.1_3047275_3049483_-	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|171aa|up_6|NZ_CP022524.1_3049556_3050069_-	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional	NA|817aa|up_5|NZ_CP022524.1_3050081_3052532_-	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ	NA|555aa|up_4|NZ_CP022524.1_3052544_3054209_-	COG0661, AarF, Predicted unusual protein kinase [General function prediction only]	NA|166aa|up_3|NZ_CP022524.1_3054506_3055004_-	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|460aa|up_2|NZ_CP022524.1_3055032_3056412_-	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase	NA|49aa|up_1|NZ_CP022524.1_3056716_3056863_-	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|193aa|up_0|NZ_CP022524.1_3056892_3057471_-	pfam04647, AgrB, Accessory gene regulator B	NA|222aa|down_0|NZ_CP022524.1_3059612_3060278_+	NA	NA|901aa|down_1|NZ_CP022524.1_3060783_3063486_-	cd01948, EAL, EAL domain	NA|517aa|down_2|NZ_CP022524.1_3063511_3065062_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|571aa|down_3|NZ_CP022524.1_3065384_3067097_-	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]	NA|87aa|down_4|NZ_CP022524.1_3067450_3067711_-	pfam00381, PTS-HPr, PTS HPr component phosphorylation site	NA|404aa|down_5|NZ_CP022524.1_3067903_3069115_-	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli	NA|578aa|down_6|NZ_CP022524.1_3069346_3071080_-	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX	NA|133aa|down_7|NZ_CP022524.1_3071119_3071518_-	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|516aa|down_8|NZ_CP022524.1_3071520_3073068_-	cd01948, EAL, EAL domain	NA|302aa|down_9|NZ_CP022524.1_3073382_3074288_-	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	16	3058918-3059008	14	CRISPRCasFinder	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TTTCTTTTACAGCTTCTAAACATAT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA|222aa|down_0|NZ_CP022524.1_3059612_3060278_+	NA|205aa|up_9|NZ_CP022524.1_3046172_3046787_-	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|150aa|up_8|NZ_CP022524.1_3046801_3047251_-	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional	NA|736aa|up_7|NZ_CP022524.1_3047275_3049483_-	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|171aa|up_6|NZ_CP022524.1_3049556_3050069_-	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional	NA|817aa|up_5|NZ_CP022524.1_3050081_3052532_-	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ	NA|555aa|up_4|NZ_CP022524.1_3052544_3054209_-	COG0661, AarF, Predicted unusual protein kinase [General function prediction only]	NA|166aa|up_3|NZ_CP022524.1_3054506_3055004_-	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|460aa|up_2|NZ_CP022524.1_3055032_3056412_-	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase	NA|49aa|up_1|NZ_CP022524.1_3056716_3056863_-	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|193aa|up_0|NZ_CP022524.1_3056892_3057471_-	pfam04647, AgrB, Accessory gene regulator B	NA|222aa|down_0|NZ_CP022524.1_3059612_3060278_+	NA	NA|901aa|down_1|NZ_CP022524.1_3060783_3063486_-	cd01948, EAL, EAL domain	NA|517aa|down_2|NZ_CP022524.1_3063511_3065062_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|571aa|down_3|NZ_CP022524.1_3065384_3067097_-	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]	NA|87aa|down_4|NZ_CP022524.1_3067450_3067711_-	pfam00381, PTS-HPr, PTS HPr component phosphorylation site	NA|404aa|down_5|NZ_CP022524.1_3067903_3069115_-	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli	NA|578aa|down_6|NZ_CP022524.1_3069346_3071080_-	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX	NA|133aa|down_7|NZ_CP022524.1_3071119_3071518_-	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|516aa|down_8|NZ_CP022524.1_3071520_3073068_-	cd01948, EAL, EAL domain	NA|302aa|down_9|NZ_CP022524.1_3073382_3074288_-	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	17	3271759-3273688	15,8,10,16	CRISPRCasFinder,CRT,PILER-CR,CRISPRCasFinder	no	cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6,WYL	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Unclear	ATTTACATACCACTTAGTTAATATAAAAC,ATTTACATACCACTTAGTTAATATAAAAC,GTTTTATATTAACTAAGTGGTATGTAAAT,ATTTACATACCACTTAGTTAATATAAAAC	29,29,29,29	0	0	NA	NA	I-A:I-A:I-A:I-A	27,29,26,27	29	Unclear	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|67aa|up_7|NZ_CP022524.1_3264652_3264853_+,NA|260aa|up_1|NZ_CP022524.1_3270035_3270815_+,NA	NA|740aa|up_9|NZ_CP022524.1_3258999_3261219_-	cd01948, EAL, EAL domain	NA|885aa|up_8|NZ_CP022524.1_3261494_3264149_-	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional	NA|67aa|up_7|NZ_CP022524.1_3264652_3264853_+	NA	NA|197aa|up_6|NZ_CP022524.1_3265059_3265650_-	PRK08305, spoVFB, dipicolinate synthase subunit B; Reviewed	NA|292aa|up_5|NZ_CP022524.1_3265652_3266528_-	PRK08306, PRK08306, dipicolinate synthase subunit DpsA	NA|464aa|up_4|NZ_CP022524.1_3266603_3267995_-	cd17633, AFD_YhfT-like, fatty acid-CoA ligase VraA	NA|379aa|up_3|NZ_CP022524.1_3267998_3269135_-	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine	NA|182aa|up_2|NZ_CP022524.1_3269166_3269712_-	pfam02632, BioY, BioY family	NA|260aa|up_1|NZ_CP022524.1_3270035_3270815_+	NA	NA|143aa|up_0|NZ_CP022524.1_3271269_3271698_-	PRK10562, PRK10562, putative acetyltransferase; Provisional	cas2|89aa|down_0|NZ_CP022524.1_3273871_3274138_-	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	cas1|327aa|down_1|NZ_CP022524.1_3274140_3275121_-	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP	cas4|173aa|down_2|NZ_CP022524.1_3275123_3275642_-	pfam01930, Cas_Cas4, Domain of unknown function DUF83	cas3|774aa|down_3|NZ_CP022524.1_3275689_3278011_-	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3	cas5|234aa|down_4|NZ_CP022524.1_3278021_3278723_-	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|305aa|down_5|NZ_CP022524.1_3278724_3279639_-	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7	cas8b2|626aa|down_6|NZ_CP022524.1_3279640_3281518_-	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1	cas6|246aa|down_7|NZ_CP022524.1_3281523_3282261_-	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6	WYL|306aa|down_8|NZ_CP022524.1_3282338_3283256_-	pfam13280, WYL, WYL domain	NA|639aa|down_9|NZ_CP022524.1_3283534_3285451_-	pfam02687, FtsX, FtsX-like permease family
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	18	3619340-3620514	9	CRT	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	GCTCCNNTNNNTCCTGTTGNNCC	23	0	0	NA	NA	NA	17	17	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA,NA	NA|85aa|up_9|NZ_CP022524.1_3607442_3607697_-	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type	NA|373aa|up_8|NZ_CP022524.1_3607818_3608937_-	cd05670, M20_Acy1_YkuR-like, M20 Peptidase aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins	NA|398aa|up_7|NZ_CP022524.1_3609142_3610336_-	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form	NA|294aa|up_6|NZ_CP022524.1_3610658_3611540_+	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional	NA|334aa|up_5|NZ_CP022524.1_3611964_3612966_+	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional	NA|296aa|up_4|NZ_CP022524.1_3613082_3613970_+	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional	NA|250aa|up_3|NZ_CP022524.1_3614036_3614786_+	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional	NA|239aa|up_2|NZ_CP022524.1_3615045_3615762_+	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA|330aa|up_1|NZ_CP022524.1_3616213_3617203_-	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily	NA|252aa|up_0|NZ_CP022524.1_3617642_3618398_+	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional	NA|180aa|down_0|NZ_CP022524.1_3620957_3621497_-	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]	NA|428aa|down_1|NZ_CP022524.1_3621824_3623108_-	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|592aa|down_2|NZ_CP022524.1_3623556_3625332_-	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]	NA|190aa|down_3|NZ_CP022524.1_3625543_3626113_-	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]	NA|212aa|down_4|NZ_CP022524.1_3626296_3626932_-	PRK05813, PRK05813, single-stranded DNA-binding protein; Provisional	NA|294aa|down_5|NZ_CP022524.1_3627599_3628481_-	pfam01925, TauE, Sulfite exporter TauE/SafE	NA|336aa|down_6|NZ_CP022524.1_3628600_3629608_-	PRK13969, PRK13969, proline racemase; Provisional	NA|161aa|down_7|NZ_CP022524.1_3629627_3630110_-	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein	NA|156aa|down_8|NZ_CP022524.1_3630127_3630595_-	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein	NA|253aa|down_9|NZ_CP022524.1_3630609_3631368_-	TIGR04482, D_pro_red_PrdD, proline reductase cluster protein PrdD
GCF_002234355.1_ASM223435v1	NZ_CP022524	Clostridioides difficile strain DH/NAP11/106/ST-42 chromosome, complete genome	19	3737296-3738628	10	CRT	no		csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	Orphan	TGNTCCTGTTGCTCCTGTTGNNCCTNTT	28	1	4	3737924-3737949|3737924-3737949|3737924-3737949|3737924-3737949	NZ_CP022524.1_414116-414091|NZ_CP022524.1_414026-414001|NZ_CP022524.1_414314-414289|NZ_CP022524.1_413828-413803	NA	18	18	Orphan	csa3,WYL,cas3,cas14j,DEDDh,DinG,cas14k,RT,cas5,cas7,cas6,cas2,cas1,cas4,cas8b2	NA|570aa|up_8|NZ_CP022524.1_3728693_3730403_-,NA|125aa|up_7|NZ_CP022524.1_3730485_3730860_-,NA	NA|291aa|up_9|NZ_CP022524.1_3727806_3728679_-	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component	NA|570aa|up_8|NZ_CP022524.1_3728693_3730403_-	NA	NA|125aa|up_7|NZ_CP022524.1_3730485_3730860_-	NA	NA|194aa|up_6|NZ_CP022524.1_3731116_3731698_-	pfam04647, AgrB, Accessory gene regulator B	NA|47aa|up_5|NZ_CP022524.1_3731756_3731897_-	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide	NA|439aa|up_4|NZ_CP022524.1_3731908_3733225_-	cd16935, HATPase_AgrC-ComD-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing	NA|237aa|up_3|NZ_CP022524.1_3733218_3733929_-	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]	NA|192aa|up_2|NZ_CP022524.1_3734367_3734943_-	pfam06353, DUF1062, Protein of unknown function (DUF1062)	NA|93aa|up_1|NZ_CP022524.1_3735235_3735514_-	pfam08765, Mor, Mor transcription activator family	NA|254aa|up_0|NZ_CP022524.1_3735822_3736584_-	COG1600, COG1600, Uncharacterized Fe-S protein [Energy production and conversion]	NA|359aa|down_0|NZ_CP022524.1_3738876_3739953_-	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide	NA|195aa|down_1|NZ_CP022524.1_3740264_3740849_-	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed	NA|161aa|down_2|NZ_CP022524.1_3740845_3741328_-	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|472aa|down_3|NZ_CP022524.1_3741526_3742942_-	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|223aa|down_4|NZ_CP022524.1_3743056_3743725_+	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]	NA|173aa|down_5|NZ_CP022524.1_3743900_3744419_-	cd20609, nitroreductase, nitroreductase family protein	NA|108aa|down_6|NZ_CP022524.1_3744570_3744894_+	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|195aa|down_7|NZ_CP022524.1_3744898_3745483_-	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1	NA|152aa|down_8|NZ_CP022524.1_3745531_3745987_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|513aa|down_9|NZ_CP022524.1_3746868_3748407_+	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
