assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	1	337992-338790	1	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGNGCCGCCGGNN	18	0	0	NA	NA	NA	15	15	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP017593.1_337507_337690_-,NA	NA|398aa|up_9|NZ_CP017593.1_327685_328879_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP017593.1_328914_330597_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP017593.1_330613_332809_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP017593.1_332922_334056_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP017593.1_334052_334673_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP017593.1_334769_335351_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP017593.1_335280_336006_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP017593.1_336095_337016_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP017593.1_337055_337484_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP017593.1_337507_337690_-	NA	NA|537aa|down_0|NZ_CP017593.1_343801_345412_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP017593.1_345435_346344_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP017593.1_346567_348463_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP017593.1_348459_350076_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP017593.1_350072_354065_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP017593.1_354061_354370_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP017593.1_354372_355914_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP017593.1_355962_356256_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP017593.1_356285_356576_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP017593.1_356586_357474_+	pfam14011, ESX-1_EspG, EspG family
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	2	342175-343143	2	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGCNCCGCCGNNGCCG	21	1	3	343015-343038|343015-343038|343015-343038	NZ_CP017593.1_1230629-1230606|NZ_CP017593.1_2435977-2436000|NZ_CP017593.1_2703555-2703532	NA	11	11	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP017593.1_337507_337690_-,NA	NA|398aa|up_9|NZ_CP017593.1_327685_328879_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP017593.1_328914_330597_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP017593.1_330613_332809_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP017593.1_332922_334056_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP017593.1_334052_334673_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP017593.1_334769_335351_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP017593.1_335280_336006_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP017593.1_336095_337016_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP017593.1_337055_337484_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP017593.1_337507_337690_-	NA	NA|537aa|down_0|NZ_CP017593.1_343801_345412_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP017593.1_345435_346344_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP017593.1_346567_348463_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP017593.1_348459_350076_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP017593.1_350072_354065_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP017593.1_354061_354370_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP017593.1_354372_355914_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP017593.1_355962_356256_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP017593.1_356285_356576_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP017593.1_356586_357474_+	pfam14011, ESX-1_EspG, EspG family
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	3	370892-371590	1	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	371180-371221|371255-371287	NZ_CP017593.1_379196-379237|NZ_CP017593.1_378011-378043	NA	10	10	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP017593.1_367904_368207_+,NA|161aa|down_1|NZ_CP017593.1_380985_381468_-,NA|410aa|down_5|NZ_CP017593.1_383584_384814_+	NA|262aa|up_9|NZ_CP017593.1_362608_363394_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP017593.1_363382_364186_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP017593.1_364195_365593_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|589aa|up_6|NZ_CP017593.1_365771_367538_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP017593.1_367680_367908_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP017593.1_367904_368207_+	NA	NA|74aa|up_3|NZ_CP017593.1_368254_368476_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP017593.1_368472_368898_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP017593.1_369033_369666_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP017593.1_369662_370571_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP017593.1_380326_380998_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP017593.1_380985_381468_-	NA	NA|239aa|down_2|NZ_CP017593.1_381525_382242_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP017593.1_382343_383000_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP017593.1_383069_383561_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP017593.1_383584_384814_+	NA	NA|621aa|down_6|NZ_CP017593.1_384968_386831_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP017593.1_386902_387289_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP017593.1_387291_387954_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP017593.1_388014_388899_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	4	635584-635721	3	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGACCACGCCGGTG	18	2	3	635602-635619|635602-635619|635686-635703	NZ_CP017593.1_23791-23808|NZ_CP017593.1_1426971-1426988|NZ_CP017593.1_987288-987305	NA	3	3	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|54aa|up_7|NZ_CP017593.1_626338_626500_-,NA|478aa|up_0|NZ_CP017593.1_632599_634033_-,NA|450aa|down_2|NZ_CP017593.1_637356_638706_-,NA|93aa|down_5|NZ_CP017593.1_640236_640515_-	NA|325aa|up_9|NZ_CP017593.1_624108_625083_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP017593.1_625124_626342_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP017593.1_626338_626500_-	NA	NA|106aa|up_6|NZ_CP017593.1_626546_626864_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|623aa|up_5|NZ_CP017593.1_627010_628879_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP017593.1_628774_629782_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP017593.1_629863_630742_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP017593.1_630758_631553_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP017593.1_631549_632590_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP017593.1_632599_634033_-	NA	NA|211aa|down_0|NZ_CP017593.1_636044_636677_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP017593.1_636673_637336_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP017593.1_637356_638706_-	NA	NA|381aa|down_3|NZ_CP017593.1_638717_639860_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP017593.1_639874_640177_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP017593.1_640236_640515_-	NA	NA|418aa|down_6|NZ_CP017593.1_640511_641765_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP017593.1_641884_642271_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP017593.1_642333_643218_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP017593.1_643313_644216_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	5	696322-696398	2	CRISPRCasFinder	no	c2c9_V-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|136aa|up_9|NZ_CP017593.1_682217_682625_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP017593.1_682684_683371_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP017593.1_683524_686158_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP017593.1_686180_688568_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP017593.1_688705_689428_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP017593.1_689424_690222_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP017593.1_690223_691111_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP017593.1_691116_692331_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|344aa|up_1|NZ_CP017593.1_692327_693359_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|482aa|up_0|NZ_CP017593.1_693355_694801_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP017593.1_697533_699084_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP017593.1_699135_699528_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP017593.1_699524_699782_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP017593.1_699964_701200_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP017593.1_701450_701864_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP017593.1_701860_702097_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP017593.1_702200_702707_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP017593.1_702820_703291_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP017593.1_703334_704096_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP017593.1_704152_704464_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	6	1588677-1589573	3	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1588877-1588898	NZ_CP017593.1_1225722-1225701	NA	12	12	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP017593.1_1580440_1580758_+,NA	NA|103aa|up_9|NZ_CP017593.1_1577955_1578264_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP017593.1_1578260_1579880_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP017593.1_1580440_1580758_+	NA	NA|209aa|up_6|NZ_CP017593.1_1580892_1581519_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP017593.1_1581584_1581917_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP017593.1_1581932_1583189_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP017593.1_1583316_1584528_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP017593.1_1584600_1586079_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP017593.1_1586075_1587461_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP017593.1_1587538_1588573_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP017593.1_1590601_1591003_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP017593.1_1590999_1591257_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP017593.1_1591339_1592299_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP017593.1_1592323_1593286_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP017593.1_1593419_1594022_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP017593.1_1594102_1596070_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP017593.1_1596087_1596912_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP017593.1_1597080_1597563_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP017593.1_1597634_1598459_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP017593.1_1598655_1599594_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	7	1589662-1589747	4	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP017593.1_1580440_1580758_+,NA	NA|103aa|up_9|NZ_CP017593.1_1577955_1578264_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP017593.1_1578260_1579880_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP017593.1_1580440_1580758_+	NA	NA|209aa|up_6|NZ_CP017593.1_1580892_1581519_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP017593.1_1581584_1581917_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP017593.1_1581932_1583189_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP017593.1_1583316_1584528_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP017593.1_1584600_1586079_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP017593.1_1586075_1587461_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP017593.1_1587538_1588573_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP017593.1_1590601_1591003_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP017593.1_1590999_1591257_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP017593.1_1591339_1592299_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP017593.1_1592323_1593286_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP017593.1_1593419_1594022_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP017593.1_1594102_1596070_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP017593.1_1596087_1596912_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP017593.1_1597080_1597563_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP017593.1_1597634_1598459_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP017593.1_1598655_1599594_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	8	1873848-1874023	1	PILER-CR	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGTTGCCGTACAA	18	0	0	NA	NA	NA	2	2	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|269aa|up_2|NZ_CP017593.1_1866772_1867579_+,NA	NA|202aa|up_9|NZ_CP017593.1_1861314_1861920_+	PRK00028, infC, translation initiation factor IF-3; Reviewed	NA|65aa|up_8|NZ_CP017593.1_1861969_1862164_+	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed	NA|130aa|up_7|NZ_CP017593.1_1862225_1862615_+	PRK05185, rplT, 50S ribosomal protein L20; Provisional	NA|261aa|up_6|NZ_CP017593.1_1862647_1863430_+	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis]	NA|352aa|up_5|NZ_CP017593.1_1863440_1864496_-	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|311aa|up_4|NZ_CP017593.1_1864805_1865738_+	pfam00934, PE, PE family	NA|317aa|up_3|NZ_CP017593.1_1865815_1866766_+	cd07302, CHD, cyclase homology domain	NA|269aa|up_2|NZ_CP017593.1_1866772_1867579_+	NA	NA|342aa|up_1|NZ_CP017593.1_1867774_1868800_+	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated	NA|832aa|up_0|NZ_CP017593.1_1868799_1871295_+	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed	NA|353aa|down_0|NZ_CP017593.1_1874639_1875698_+	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated	NA|405aa|down_1|NZ_CP017593.1_1875694_1876909_+	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ	NA|295aa|down_2|NZ_CP017593.1_1876905_1877790_+	PRK00942, PRK00942, acetylglutamate kinase; Provisional	NA|401aa|down_3|NZ_CP017593.1_1877786_1878989_+	PRK03244, argD, acetylornithine transaminase	NA|308aa|down_4|NZ_CP017593.1_1878985_1879909_+	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional	NA|171aa|down_5|NZ_CP017593.1_1879905_1880418_+	PRK03341, PRK03341, arginine repressor; Provisional	NA|399aa|down_6|NZ_CP017593.1_1880426_1881623_+	PRK00509, PRK00509, argininosuccinate synthase; Provisional	NA|471aa|down_7|NZ_CP017593.1_1881702_1883115_+	PRK00855, PRK00855, argininosuccinate lyase; Provisional	NA|354aa|down_8|NZ_CP017593.1_1883223_1884285_+	COG3424, BcsA, Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|2127aa|down_9|NZ_CP017593.1_1884367_1890748_+	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	9	2086992-2087246	4	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2087073-2087090|2087073-2087090|2087163-2087180	NZ_CP017593.1_405492-405475|NZ_CP017593.1_611656-611639|NZ_CP017593.1_3452878-3452861	NA	5	5	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP017593.1_2086351_2086615_-,NA	NA|165aa|up_9|NZ_CP017593.1_2072701_2073196_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP017593.1_2073543_2074221_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP017593.1_2074579_2077405_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP017593.1_2077631_2078492_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP017593.1_2078532_2079399_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP017593.1_2079403_2081290_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP017593.1_2081305_2083339_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP017593.1_2083458_2085684_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP017593.1_2085959_2086355_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP017593.1_2086351_2086615_-	NA	NA|346aa|down_0|NZ_CP017593.1_2088383_2089421_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP017593.1_2089420_2090788_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP017593.1_2090961_2092398_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP017593.1_2092433_2093885_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP017593.1_2093914_2094865_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP017593.1_2094879_2095296_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP017593.1_2095573_2095996_+	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|101aa|down_7|NZ_CP017593.1_2096044_2096347_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP017593.1_2096343_2096658_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP017593.1_2096657_2098391_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	10	2169926-2170145	5	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP017593.1_2158674_2159082_-,NA|127aa|down_5|NZ_CP017593.1_2177661_2178042_-	NA|155aa|up_9|NZ_CP017593.1_2152002_2152467_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP017593.1_2152642_2154865_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP017593.1_2154902_2155346_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP017593.1_2155459_2156053_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP017593.1_2156135_2156741_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP017593.1_2156840_2157845_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP017593.1_2157944_2158697_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP017593.1_2158674_2159082_-	NA	NA|767aa|up_1|NZ_CP017593.1_2159216_2161517_+	PLN02892, PLN02892, isocitrate lyase	NA|421aa|up_0|NZ_CP017593.1_2165502_2166764_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|155aa|down_0|NZ_CP017593.1_2172172_2172637_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP017593.1_2172734_2173598_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP017593.1_2173635_2174907_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP017593.1_2175178_2176294_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP017593.1_2176284_2177625_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP017593.1_2177661_2178042_-	NA	NA|621aa|down_6|NZ_CP017593.1_2178198_2180061_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP017593.1_2180068_2180548_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP017593.1_2180784_2181558_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP017593.1_2181561_2182329_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	11	3126620-3127693	2,6,5	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-C,Type III-A,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	13,13,14	14	TypeIII-D,TypeIII-C,TypeIII-A,TypeIII-B	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP017593.1_3119899_3120154_-,NA|135aa|up_7|NZ_CP017593.1_3120301_3120706_+,NA|64aa|up_6|NZ_CP017593.1_3120702_3120894_+,NA|86aa|up_4|NZ_CP017593.1_3122480_3122738_+,NA|104aa|up_3|NZ_CP017593.1_3122842_3123154_+,NA|203aa|up_2|NZ_CP017593.1_3123573_3124182_+,NA	NA|92aa|up_9|NZ_CP017593.1_3119448_3119724_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP017593.1_3119899_3120154_-	NA	NA|135aa|up_7|NZ_CP017593.1_3120301_3120706_+	NA	NA|64aa|up_6|NZ_CP017593.1_3120702_3120894_+	NA	NA|385aa|up_5|NZ_CP017593.1_3121092_3122247_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP017593.1_3122480_3122738_+	NA	NA|104aa|up_3|NZ_CP017593.1_3122842_3123154_+	NA	NA|203aa|up_2|NZ_CP017593.1_3123573_3124182_+	NA	NA|470aa|up_1|NZ_CP017593.1_3124252_3125662_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP017593.1_3125658_3126471_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP017593.1_3127724_3128986_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	csm3gr7|237aa|down_1|NZ_CP017593.1_3129349_3130060_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_2|NZ_CP017593.1_3130069_3130444_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_3|NZ_CP017593.1_3130440_3132879_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_4|NZ_CP017593.1_3132875_3133598_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_5|NZ_CP017593.1_3133997_3134543_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|295aa|down_6|NZ_CP017593.1_3134814_3135699_-	COG2253, COG2253, Uncharacterized conserved protein [Function unknown]	NA|296aa|down_7|NZ_CP017593.1_3135701_3136589_-	pfam09407, AbiEi_1, AbiEi antitoxin C-terminal domain	NA|182aa|down_8|NZ_CP017593.1_3136893_3137439_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|90aa|down_9|NZ_CP017593.1_3137435_3137705_-	COG5552, COG5552, Uncharacterized conserved protein [Function unknown]
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	12	3668900-3669018	7	CRISPRCasFinder	no	cas3	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Unclear	GCCCCTGTGAGTCGAGTGAGCGGAACGAAC	30	1	1	3668930-3668988	NZ_CP017593.1_3668993-3669051	NA	1	1	Unclear	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|138aa|down_6|NZ_CP017593.1_3674651_3675065_-,NA|126aa|down_7|NZ_CP017593.1_3675099_3675477_-	NA|719aa|up_9|NZ_CP017593.1_3655726_3657883_+	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism]	NA|223aa|up_8|NZ_CP017593.1_3657879_3658548_-	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]	NA|395aa|up_7|NZ_CP017593.1_3658648_3659833_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|765aa|up_6|NZ_CP017593.1_3659837_3662132_+	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]	NA|390aa|up_5|NZ_CP017593.1_3662120_3663290_-	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|175aa|up_4|NZ_CP017593.1_3663314_3663839_-	PLN02948, PLN02948, phosphoribosylaminoimidazole carboxylase	NA|430aa|up_3|NZ_CP017593.1_3663835_3665125_-	TIGR01161, N5-carboxyaminoimidazole_ribonucleotide_synthase, phosphoribosylaminoimidazole carboxylase, PurK protein	NA|273aa|up_2|NZ_CP017593.1_3665078_3665897_+	COG2246, COG2246, Predicted membrane protein [Function unknown]	NA|173aa|up_1|NZ_CP017593.1_3665851_3666370_-	pfam03703, bPH_2, Bacterial PH domain	NA|267aa|up_0|NZ_CP017593.1_3666412_3667213_-	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]	NA|223aa|down_0|NZ_CP017593.1_3669284_3669953_+	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|298aa|down_1|NZ_CP017593.1_3669993_3670887_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|144aa|down_2|NZ_CP017593.1_3670883_3671315_+	COG2166, sufE, Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]	NA|601aa|down_3|NZ_CP017593.1_3671422_3673225_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|262aa|down_4|NZ_CP017593.1_3673234_3674020_-	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed	NA|146aa|down_5|NZ_CP017593.1_3674016_3674454_-	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]	NA|138aa|down_6|NZ_CP017593.1_3674651_3675065_-	NA	NA|126aa|down_7|NZ_CP017593.1_3675099_3675477_-	NA	NA|450aa|down_8|NZ_CP017593.1_3675510_3676860_-	PRK08297, PRK08297, L-lysine aminotransferase; Provisional	NA|151aa|down_9|NZ_CP017593.1_3676910_3677363_-	smart00344, HTH_ASNC, helix_turn_helix ASNC type
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	13	3753093-3753669	6	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGTTGCCNCCGNNGCCGCCG	25	0	0	NA	NA	NA	7	7	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|110aa|up_0|NZ_CP017593.1_3750342_3750672_+,NA|96aa|down_4|NZ_CP017593.1_3767901_3768189_-,NA|87aa|down_8|NZ_CP017593.1_3781308_3781569_-	NA|147aa|up_9|NZ_CP017593.1_3730182_3730623_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_8|NZ_CP017593.1_3730656_3731526_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_7|NZ_CP017593.1_3731546_3732557_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_6|NZ_CP017593.1_3732841_3733474_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_5|NZ_CP017593.1_3733540_3734770_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_4|NZ_CP017593.1_3735052_3736402_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_CP017593.1_3736413_3737553_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_CP017593.1_3737549_3738281_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|346aa|up_1|NZ_CP017593.1_3749403_3750441_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|110aa|up_0|NZ_CP017593.1_3750342_3750672_+	NA	NA|86aa|down_0|NZ_CP017593.1_3755771_3756029_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP017593.1_3756284_3765758_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP017593.1_3766383_3766830_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|273aa|down_3|NZ_CP017593.1_3766866_3767685_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP017593.1_3767901_3768189_-	NA	NA|265aa|down_5|NZ_CP017593.1_3779918_3780713_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_6|NZ_CP017593.1_3780794_3781166_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|137aa|down_7|NZ_CP017593.1_3781063_3781474_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_8|NZ_CP017593.1_3781308_3781569_-	NA	NA|130aa|down_9|NZ_CP017593.1_3781683_3782073_+	pfam05305, DUF732, Protein of unknown function (DUF732)
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	14	3862601-3862690	8	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|77aa|up_7|NZ_CP017593.1_3854635_3854866_+,NA|121aa|up_6|NZ_CP017593.1_3854969_3855332_-,NA|73aa|up_1|NZ_CP017593.1_3860664_3860883_-,NA|121aa|down_0|NZ_CP017593.1_3863675_3864038_-,NA|52aa|down_2|NZ_CP017593.1_3865879_3866035_-,NA|52aa|down_3|NZ_CP017593.1_3866059_3866215_-,NA|238aa|down_6|NZ_CP017593.1_3870250_3870964_-	NA|169aa|up_9|NZ_CP017593.1_3852946_3853453_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|409aa|up_8|NZ_CP017593.1_3853449_3854676_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_7|NZ_CP017593.1_3854635_3854866_+	NA	NA|121aa|up_6|NZ_CP017593.1_3854969_3855332_-	NA	NA|177aa|up_5|NZ_CP017593.1_3856290_3856821_+	pfam00823, PPE, PPE family	NA|252aa|up_4|NZ_CP017593.1_3857138_3857894_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|337aa|up_3|NZ_CP017593.1_3857977_3858988_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|553aa|up_2|NZ_CP017593.1_3859013_3860672_-	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|73aa|up_1|NZ_CP017593.1_3860664_3860883_-	NA	NA|181aa|up_0|NZ_CP017593.1_3861764_3862307_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_CP017593.1_3863675_3864038_-	NA	NA|179aa|down_1|NZ_CP017593.1_3864200_3864737_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_CP017593.1_3865879_3866035_-	NA	NA|52aa|down_3|NZ_CP017593.1_3866059_3866215_-	NA	NA|461aa|down_4|NZ_CP017593.1_3867407_3868790_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|474aa|down_5|NZ_CP017593.1_3868827_3870249_-	pfam01256, Carb_kinase, Carbohydrate kinase	NA|238aa|down_6|NZ_CP017593.1_3870250_3870964_-	NA	NA|285aa|down_7|NZ_CP017593.1_3870974_3871829_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_8|NZ_CP017593.1_3872050_3873925_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_9|NZ_CP017593.1_3873946_3874423_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	15	3947934-3948878	7	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGNNNCGGCGGCNCCGGCGGC	24	0	0	NA	NA	NA	12	12	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_5|NZ_CP017593.1_3969023_3969863_+	NA|358aa|up_9|NZ_CP017593.1_3931621_3932695_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|351aa|up_8|NZ_CP017593.1_3932684_3933737_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|401aa|up_7|NZ_CP017593.1_3933736_3934939_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|281aa|up_6|NZ_CP017593.1_3934958_3935801_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_5|NZ_CP017593.1_3935835_3936600_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_4|NZ_CP017593.1_3936825_3937779_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_3|NZ_CP017593.1_3937803_3937995_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_2|NZ_CP017593.1_3938209_3939412_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_1|NZ_CP017593.1_3939436_3940558_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_0|NZ_CP017593.1_3940628_3942137_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|516aa|down_0|NZ_CP017593.1_3951774_3953322_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|down_1|NZ_CP017593.1_3953318_3954155_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|down_2|NZ_CP017593.1_3960463_3961120_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_3|NZ_CP017593.1_3966416_3968063_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_4|NZ_CP017593.1_3968136_3968928_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_5|NZ_CP017593.1_3969023_3969863_+	NA	NA|399aa|down_6|NZ_CP017593.1_3969917_3971114_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_7|NZ_CP017593.1_3971142_3971853_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_8|NZ_CP017593.1_3971917_3972961_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_9|NZ_CP017593.1_3973113_3974025_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	16	3964560-3965709	8	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CNNCGGCGGCNNCGGCGGCNNNGGCGGNNNCGGCGGC	37	8	11	3964687-3964733|3964843-3964886|3964924-3964955|3964993-3965045|3965083-3965123|3965230-3965264|3965302-3965339|3965440-3965465|3965440-3965465|3965440-3965465|3965440-3965465	NZ_CP017593.1_3964079-3964125|NZ_CP017593.1_3964234-3964277|NZ_CP017593.1_3964315-3964346|NZ_CP017593.1_3964384-3964436|NZ_CP017593.1_3964474-3964514|NZ_CP017593.1_3964016-3964050|NZ_CP017593.1_3964088-3964125|NZ_CP017593.1_3956492-3956517|NZ_CP017593.1_3956837-3956862|NZ_CP017593.1_3957182-3957207|NZ_CP017593.1_3964306-3964331	NA	15	15	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP017593.1_3969023_3969863_+	NA|281aa|up_9|NZ_CP017593.1_3934958_3935801_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_8|NZ_CP017593.1_3935835_3936600_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_7|NZ_CP017593.1_3936825_3937779_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_6|NZ_CP017593.1_3937803_3937995_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_5|NZ_CP017593.1_3938209_3939412_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_4|NZ_CP017593.1_3939436_3940558_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_3|NZ_CP017593.1_3940628_3942137_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|516aa|up_2|NZ_CP017593.1_3951774_3953322_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP017593.1_3953318_3954155_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP017593.1_3960463_3961120_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP017593.1_3966416_3968063_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP017593.1_3968136_3968928_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP017593.1_3969023_3969863_+	NA	NA|399aa|down_3|NZ_CP017593.1_3969917_3971114_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP017593.1_3971142_3971853_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP017593.1_3971917_3972961_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP017593.1_3973113_3974025_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP017593.1_3974040_3975105_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP017593.1_3975121_3976306_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP017593.1_3976347_3977379_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002116755.1_ASM211675v1	NZ_CP017593	Mycobacterium tuberculosis strain Beijing-like/35049 chromosome, complete genome	17	4125834-4125922	9	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP017593.1_4116420_4117191_-,NA|119aa|up_3|NZ_CP017593.1_4122325_4122682_+,NA|52aa|up_2|NZ_CP017593.1_4122781_4122937_+,NA|233aa|up_0|NZ_CP017593.1_4124938_4125637_-,NA|126aa|down_6|NZ_CP017593.1_4131157_4131535_+	NA|288aa|up_9|NZ_CP017593.1_4114802_4115666_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP017593.1_4116420_4117191_-	NA	NA|549aa|up_7|NZ_CP017593.1_4117187_4118834_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP017593.1_4118830_4119694_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP017593.1_4119686_4120613_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP017593.1_4120614_4122240_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP017593.1_4122325_4122682_+	NA	NA|52aa|up_2|NZ_CP017593.1_4122781_4122937_+	NA	NA|652aa|up_1|NZ_CP017593.1_4122947_4124903_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP017593.1_4124938_4125637_-	NA	NA|173aa|down_0|NZ_CP017593.1_4125982_4126501_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP017593.1_4126501_4127485_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP017593.1_4127477_4128671_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP017593.1_4128676_4129498_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP017593.1_4129629_4130313_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP017593.1_4130312_4131050_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP017593.1_4131157_4131535_+	NA	NA|225aa|down_7|NZ_CP017593.1_4131633_4132308_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP017593.1_4132413_4133208_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP017593.1_4133214_4133670_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
