assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	1	3524107-3524195	1	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	CGCGGCTCCGCCCGCGCGGCGATCAGTG	28	1	1	3524135-3524167	NZ_CP019458.1_8633824-8633792	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|77aa|up_3|NZ_CP019458.1_3520265_3520496_+,NA|504aa|up_2|NZ_CP019458.1_3520587_3522099_+,NA|93aa|down_1|NZ_CP019458.1_3526274_3526553_-,NA|68aa|down_5|NZ_CP019458.1_3529492_3529696_-	NA|416aa|up_9|NZ_CP019458.1_3512397_3513645_-	pfam17964, Big_10, Bacterial Ig domain	NA|133aa|up_8|NZ_CP019458.1_3513796_3514195_-	pfam12270, Cyt_c_ox_IV, Cytochrome c oxidase subunit IV	NA|580aa|up_7|NZ_CP019458.1_3514191_3515931_-	cd01662, Ubiquinol_Oxidase_I, Ubiquinol oxidase subunit I	NA|321aa|up_6|NZ_CP019458.1_3515927_3516890_-	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]	NA|470aa|up_5|NZ_CP019458.1_3517455_3518865_+	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]	NA|325aa|up_4|NZ_CP019458.1_3519116_3520091_-	cd01942, ribokinase_group_A, Ribokinase-like subgroup A	NA|77aa|up_3|NZ_CP019458.1_3520265_3520496_+	NA	NA|504aa|up_2|NZ_CP019458.1_3520587_3522099_+	NA	NA|118aa|up_1|NZ_CP019458.1_3522215_3522569_-	TIGR00049, Uncharacterized_protein_in_nifU_5'region, Iron-sulfur cluster assembly accessory protein	NA|393aa|up_0|NZ_CP019458.1_3522805_3523984_+	PRK09375, PRK09375, quinolinate synthase NadA	NA|433aa|down_0|NZ_CP019458.1_3524863_3526162_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|93aa|down_1|NZ_CP019458.1_3526274_3526553_-	NA	NA|259aa|down_2|NZ_CP019458.1_3526596_3527373_-	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]	NA|199aa|down_3|NZ_CP019458.1_3527635_3528232_+	pfam11241, DUF3043, Protein of unknown function (DUF3043)	NA|251aa|down_4|NZ_CP019458.1_3528318_3529071_+	PRK11036, PRK11036, tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA|68aa|down_5|NZ_CP019458.1_3529492_3529696_-	NA	NA|400aa|down_6|NZ_CP019458.1_3529836_3531036_+	pfam02283, CobU, Cobinamide kinase / cobinamide phosphate guanyltransferase	NA|364aa|down_7|NZ_CP019458.1_3532686_3533778_+	PRK00105, cobT, nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed	NA|252aa|down_8|NZ_CP019458.1_3533790_3534546_-	pfam02654, CobS, Cobalamin-5-phosphate synthase	NA|518aa|down_9|NZ_CP019458.1_3535535_3537089_+	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	2	3566166-3566262	2	CRISPRCasFinder	no	csa3	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Type I-A	CAGGGACCCTGGGGGCAGAGGCTCTGGGGTCAGGG	35	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|66aa|up_8|NZ_CP019458.1_3555963_3556161_+,NA	NA|317aa|up_9|NZ_CP019458.1_3554676_3555627_+	PRK05481, PRK05481, lipoyl synthase; Provisional	NA|66aa|up_8|NZ_CP019458.1_3555963_3556161_+	NA	NA|227aa|up_7|NZ_CP019458.1_3556171_3556852_+	pfam13829, DUF4191, Domain of unknown function (DUF4191)	NA|156aa|up_6|NZ_CP019458.1_3557048_3557516_-	pfam06271, RDD, RDD family	NA|470aa|up_5|NZ_CP019458.1_3557770_3559180_+	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I	NA|197aa|up_4|NZ_CP019458.1_3559274_3559865_-	pfam16640, Big_3_5, Bacterial Ig-like domain (group 3)	NA|455aa|up_3|NZ_CP019458.1_3560242_3561607_-	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]	NA|406aa|up_2|NZ_CP019458.1_3561721_3562939_-	pfam16640, Big_3_5, Bacterial Ig-like domain (group 3)	NA|213aa|up_1|NZ_CP019458.1_3563317_3563956_-	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism]	NA|611aa|up_0|NZ_CP019458.1_3564318_3566151_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|170aa|down_0|NZ_CP019458.1_3566286_3566796_-	pfam00719, Pyrophosphatase, Inorganic pyrophosphatase	NA|236aa|down_1|NZ_CP019458.1_3566879_3567587_-	pfam13305, WHG, WHG domain	NA|352aa|down_2|NZ_CP019458.1_3567706_3568762_+	cd08273, MDR8, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|211aa|down_3|NZ_CP019458.1_3568918_3569551_+	COG1802, GntR, Transcriptional regulators [Transcription]	NA|130aa|down_4|NZ_CP019458.1_3569552_3569942_-	cd20303, cupin_ChrR_1, Marinobacter hydrocarbonoclasticus anti-ECFsigma factor ChrR, and similar proteins; 2 heterologous tandem repeats of cupin domain	NA|270aa|down_5|NZ_CP019458.1_3569938_3570748_-	cd07581, nitrilase_3, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases)	NA|453aa|down_6|NZ_CP019458.1_3571052_3572411_-	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily	NA|241aa|down_7|NZ_CP019458.1_3572659_3573382_+	pfam11010, DUF2848, Protein of unknown function (DUF2848)	NA|147aa|down_8|NZ_CP019458.1_3573525_3573966_-	pfam03779, SPW, SPW repeat	NA|197aa|down_9|NZ_CP019458.1_3574362_3574953_+	cd00383, trans_reg_C, DNA-binding effector domain of two-component system response regulators
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	3	3619902-3619986	3	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	CAACATGCGGCTCCCCCGCACGG	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|107aa|up_7|NZ_CP019458.1_3607405_3607726_+,NA|367aa|up_6|NZ_CP019458.1_3607810_3608911_+,NA|405aa|up_5|NZ_CP019458.1_3608907_3610122_+,NA	NA|309aa|up_9|NZ_CP019458.1_3605025_3605952_+	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase	NA|235aa|up_8|NZ_CP019458.1_3606019_3606724_+	cd07729, AHL_lactonase_MBL-fold, quorum-quenching N-acyl-homoserine lactonase, MBL-fold metallo-hydrolase domain	NA|107aa|up_7|NZ_CP019458.1_3607405_3607726_+	NA	NA|367aa|up_6|NZ_CP019458.1_3607810_3608911_+	NA	NA|405aa|up_5|NZ_CP019458.1_3608907_3610122_+	NA	NA|1083aa|up_4|NZ_CP019458.1_3610145_3613394_-	PRK14109, PRK14109, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	NA|454aa|up_3|NZ_CP019458.1_3613615_3614977_-	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism]	NA|554aa|up_2|NZ_CP019458.1_3615407_3617069_+	cd13870, CuRO_2_CopA_like_1, The second cupredoxin domain of CopA copper resistance protein like family	NA|585aa|up_1|NZ_CP019458.1_3617201_3618956_+	PRK13981, PRK13981, NAD synthetase; Provisional	NA|262aa|up_0|NZ_CP019458.1_3618982_3619768_-	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase	NA|405aa|down_0|NZ_CP019458.1_3620947_3622162_-	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|343aa|down_1|NZ_CP019458.1_3622439_3623468_-	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2	NA|203aa|down_2|NZ_CP019458.1_3623644_3624253_-	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|541aa|down_3|NZ_CP019458.1_3624249_3625872_-	PRK14995, PRK14995, SmvA family efflux MFS transporter	NA|287aa|down_4|NZ_CP019458.1_3626129_3626990_+	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed	NA|338aa|down_5|NZ_CP019458.1_3627128_3628142_+	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit	NA|275aa|down_6|NZ_CP019458.1_3628138_3628963_+	pfam01061, ABC2_membrane, ABC-2 type transporter	NA|1213aa|down_7|NZ_CP019458.1_3629033_3632672_-	COG3903, COG3903, Predicted ATPase [General function prediction only]	NA|182aa|down_8|NZ_CP019458.1_3632696_3633242_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|266aa|down_9|NZ_CP019458.1_3633394_3634192_+	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	4	3716573-3716670	4	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	CCCGGCCCCGGCCCGCCCGCCTGAG	25	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|54aa|up_4|NZ_CP019458.1_3711326_3711488_+,NA|98aa|down_3|NZ_CP019458.1_3720070_3720364_+	NA|220aa|up_9|NZ_CP019458.1_3703971_3704631_+	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional	NA|392aa|up_8|NZ_CP019458.1_3704780_3705956_-	PRK07238, PRK07238, bifunctional RNase H/acid phosphatase; Provisional	NA|300aa|up_7|NZ_CP019458.1_3705960_3706860_-	COG1579, COG1579, Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]	NA|287aa|up_6|NZ_CP019458.1_3706774_3707635_-	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3)	NA|345aa|up_5|NZ_CP019458.1_3707730_3708765_-	cd01146, FhuD, Fe3+-siderophore binding domain FhuD	NA|54aa|up_4|NZ_CP019458.1_3711326_3711488_+	NA	NA|318aa|up_3|NZ_CP019458.1_3711720_3712674_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|362aa|up_2|NZ_CP019458.1_3712658_3713744_-	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase	NA|285aa|up_1|NZ_CP019458.1_3713809_3714664_-	PLN02864, PLN02864, enoyl-CoA hydratase	NA|226aa|up_0|NZ_CP019458.1_3715702_3716380_+	pfam13578, Methyltransf_24, Methyltransferase domain	NA|326aa|down_0|NZ_CP019458.1_3716822_3717800_+	pfam01520, Amidase_3, N-acetylmuramoyl-L-alanine amidase	NA|262aa|down_1|NZ_CP019458.1_3717997_3718783_+	pfam09849, DUF2076, Uncharacterized protein conserved in bacteria (DUF2076)	NA|337aa|down_2|NZ_CP019458.1_3718992_3720003_+	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|98aa|down_3|NZ_CP019458.1_3720070_3720364_+	NA	NA|367aa|down_4|NZ_CP019458.1_3720935_3722036_-	TIGR01577, Uncharacterized_glycosyl_hydrolase_MJ1610, oligosaccharide amylase	NA|245aa|down_5|NZ_CP019458.1_3722032_3722767_-	pfam08241, Methyltransf_11, Methyltransferase domain	NA|446aa|down_6|NZ_CP019458.1_3722849_3724187_-	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|205aa|down_7|NZ_CP019458.1_3724578_3725193_+	pfam17925, TetR_C_20, Tetracyclin repressor-like, C-terminal domain	NA|195aa|down_8|NZ_CP019458.1_3725432_3726017_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|78aa|down_9|NZ_CP019458.1_3726124_3726358_-	pfam13370, Fer4_13, 4Fe-4S single cluster domain of Ferredoxin I
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	5	3922335-3923155	1,5,1	CRT,CRISPRCasFinder,PILER-CR	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Type I-E	NCCGGAACACCCCCNCGTCGGCGGGGAGGAC,CGGAACACCCCCACGTCGGCGGGGAGGAC,CGGAACACCCCCACGTCGGCGGGGAGGAC	31,29,29	0	0	NA	NA	NA:NA:NA	13,13,10	13	TypeI-E	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|94aa|up_6|NZ_CP019458.1_3914917_3915199_-,NA|74aa|up_4|NZ_CP019458.1_3915855_3916077_-,NA|110aa|up_1|NZ_CP019458.1_3919731_3920061_-,NA|96aa|up_0|NZ_CP019458.1_3921633_3921921_+,NA|83aa|down_8|NZ_CP019458.1_3936469_3936718_-	NA|1031aa|up_9|NZ_CP019458.1_3910388_3913481_-	pfam04738, Lant_dehydr_N, Lantibiotic dehydratase, C-terminus	NA|66aa|up_8|NZ_CP019458.1_3913573_3913771_-	TIGR04363, hypothetical_protein, FxLD family lantipeptide	NA|277aa|up_7|NZ_CP019458.1_3914045_3914876_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|94aa|up_6|NZ_CP019458.1_3914917_3915199_-	NA	NA|176aa|up_5|NZ_CP019458.1_3915273_3915801_-	cd06170, LuxR_C_like, C-terminal DNA-binding domain of LuxR-like proteins	NA|74aa|up_4|NZ_CP019458.1_3915855_3916077_-	NA	NA|386aa|up_3|NZ_CP019458.1_3917864_3919022_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|192aa|up_2|NZ_CP019458.1_3919045_3919621_+	pfam13023, HD_3, HD domain	NA|110aa|up_1|NZ_CP019458.1_3919731_3920061_-	NA	NA|96aa|up_0|NZ_CP019458.1_3921633_3921921_+	NA	cas3|947aa|down_0|NZ_CP019458.1_3923406_3926247_+	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	cas8e|536aa|down_1|NZ_CP019458.1_3926843_3928451_+	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	cse2gr11|180aa|down_2|NZ_CP019458.1_3928604_3929144_+	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas7|392aa|down_3|NZ_CP019458.1_3929140_3930316_+	pfam09344, Cas_CT1975, CT1975-like protein	cas5|254aa|down_4|NZ_CP019458.1_3930312_3931074_+	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas6e|217aa|down_5|NZ_CP019458.1_3931070_3931721_+	pfam08798, CRISPR_assoc, CRISPR associated protein	cas1|320aa|down_6|NZ_CP019458.1_3931777_3932737_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|106aa|down_7|NZ_CP019458.1_3932736_3933054_+	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978)	NA|83aa|down_8|NZ_CP019458.1_3936469_3936718_-	NA	NA|406aa|down_9|NZ_CP019458.1_3936813_3938031_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	6	3933072-3936243	2,6,2,3	PILER-CR,CRISPRCasFinder,CRT,PILER-CR	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Type I-E	GGAACACCCCCGCGTCGGCGGGGACCAC,GTGGTCCCCGCCGACGCGGGGGTGTTCCG,GTGGTCCCCGCCGACGCGGGGGTGTTCCG,CGCCGGAACACCCCCACGTCGGCGGGGAGGAC	28,29,29,32	0	0	NA	NA	NA:NA:NA:NA	48,51,48,48	51	TypeI-E	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|110aa|up_9|NZ_CP019458.1_3919731_3920061_-,NA|96aa|up_8|NZ_CP019458.1_3921633_3921921_+,NA|83aa|down_0|NZ_CP019458.1_3936469_3936718_-,NA|90aa|down_2|NZ_CP019458.1_3938830_3939100_+	NA|110aa|up_9|NZ_CP019458.1_3919731_3920061_-	NA	NA|96aa|up_8|NZ_CP019458.1_3921633_3921921_+	NA	cas3|947aa|up_7|NZ_CP019458.1_3923406_3926247_+	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	cas8e|536aa|up_6|NZ_CP019458.1_3926843_3928451_+	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	cse2gr11|180aa|up_5|NZ_CP019458.1_3928604_3929144_+	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas7|392aa|up_4|NZ_CP019458.1_3929140_3930316_+	pfam09344, Cas_CT1975, CT1975-like protein	cas5|254aa|up_3|NZ_CP019458.1_3930312_3931074_+	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas6e|217aa|up_2|NZ_CP019458.1_3931070_3931721_+	pfam08798, CRISPR_assoc, CRISPR associated protein	cas1|320aa|up_1|NZ_CP019458.1_3931777_3932737_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|106aa|up_0|NZ_CP019458.1_3932736_3933054_+	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978)	NA|83aa|down_0|NZ_CP019458.1_3936469_3936718_-	NA	NA|406aa|down_1|NZ_CP019458.1_3936813_3938031_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|90aa|down_2|NZ_CP019458.1_3938830_3939100_+	NA	NA|500aa|down_3|NZ_CP019458.1_3939125_3940625_+	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|323aa|down_4|NZ_CP019458.1_3940762_3941731_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|663aa|down_5|NZ_CP019458.1_3942352_3944341_-	PRK05667, dnaG, DNA primase; Validated	NA|432aa|down_6|NZ_CP019458.1_3944415_3945711_-	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|454aa|down_7|NZ_CP019458.1_3945992_3947354_-	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|278aa|down_8|NZ_CP019458.1_3947350_3948184_-	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]	NA|763aa|down_9|NZ_CP019458.1_3948482_3950771_+	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	7	3938478-3938581	7	CRISPRCasFinder	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Type I-E	TGCTCTGCCAATTGAGCTACAGGGGA	26	0	0	NA	NA	NA	1	1	TypeI-E	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|83aa|up_1|NZ_CP019458.1_3936469_3936718_-,NA|90aa|down_0|NZ_CP019458.1_3938830_3939100_+	cas3|947aa|up_9|NZ_CP019458.1_3923406_3926247_+	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	cas8e|536aa|up_8|NZ_CP019458.1_3926843_3928451_+	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	cse2gr11|180aa|up_7|NZ_CP019458.1_3928604_3929144_+	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas7|392aa|up_6|NZ_CP019458.1_3929140_3930316_+	pfam09344, Cas_CT1975, CT1975-like protein	cas5|254aa|up_5|NZ_CP019458.1_3930312_3931074_+	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas6e|217aa|up_4|NZ_CP019458.1_3931070_3931721_+	pfam08798, CRISPR_assoc, CRISPR associated protein	cas1|320aa|up_3|NZ_CP019458.1_3931777_3932737_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|106aa|up_2|NZ_CP019458.1_3932736_3933054_+	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978)	NA|83aa|up_1|NZ_CP019458.1_3936469_3936718_-	NA	NA|406aa|up_0|NZ_CP019458.1_3936813_3938031_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|90aa|down_0|NZ_CP019458.1_3938830_3939100_+	NA	NA|500aa|down_1|NZ_CP019458.1_3939125_3940625_+	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|323aa|down_2|NZ_CP019458.1_3940762_3941731_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|663aa|down_3|NZ_CP019458.1_3942352_3944341_-	PRK05667, dnaG, DNA primase; Validated	NA|432aa|down_4|NZ_CP019458.1_3944415_3945711_-	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|454aa|down_5|NZ_CP019458.1_3945992_3947354_-	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|278aa|down_6|NZ_CP019458.1_3947350_3948184_-	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]	NA|763aa|down_7|NZ_CP019458.1_3948482_3950771_+	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite	NA|329aa|down_8|NZ_CP019458.1_3950802_3951789_-	PRK09358, PRK09358, adenosine deaminase; Provisional	NA|212aa|down_9|NZ_CP019458.1_3951956_3952592_+	cd06260, DUF820, Domain of unknown function (DUF820)
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	8	4769795-4769922	8	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	TTACTTCTCCTGCTGCTTGCGCCAGCGAATCCCCGCTTCGAGG	43	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|65aa|up_1|NZ_CP019458.1_4768491_4768686_+,NA|676aa|down_8|NZ_CP019458.1_4793248_4795276_+	NA|431aa|up_9|NZ_CP019458.1_4759825_4761118_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|111aa|up_8|NZ_CP019458.1_4761738_4762071_+	TIGR04186, conserved_hypothetical_protein, putative ATP-grasp target RiPP	NA|323aa|up_7|NZ_CP019458.1_4762078_4763047_+	TIGR04187, conserved_hypothetical_protein, ATP-grasp ribosomal peptide maturase, SAV_5884 family	NA|392aa|up_6|NZ_CP019458.1_4763043_4764219_+	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system	NA|160aa|up_5|NZ_CP019458.1_4764775_4765255_-	pfam01668, SmpB, SmpB protein	NA|404aa|up_4|NZ_CP019458.1_4765273_4766485_-	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane]	NA|304aa|up_3|NZ_CP019458.1_4766553_4767465_-	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning]	NA|230aa|up_2|NZ_CP019458.1_4767474_4768164_-	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning]	NA|65aa|up_1|NZ_CP019458.1_4768491_4768686_+	NA	NA|226aa|up_0|NZ_CP019458.1_4768825_4769503_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|449aa|down_0|NZ_CP019458.1_4771026_4772373_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|565aa|down_1|NZ_CP019458.1_4772662_4774357_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|453aa|down_2|NZ_CP019458.1_4780720_4782079_+	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold	NA|458aa|down_3|NZ_CP019458.1_4782103_4783477_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|294aa|down_4|NZ_CP019458.1_4783473_4784355_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|883aa|down_5|NZ_CP019458.1_4784743_4787392_+	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	NA|614aa|down_6|NZ_CP019458.1_4787461_4789303_+	pfam11380, Stealth_CR2, Stealth protein CR2, conserved region 2	NA|352aa|down_7|NZ_CP019458.1_4789275_4790331_+	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family	NA|676aa|down_8|NZ_CP019458.1_4793248_4795276_+	NA	NA|668aa|down_9|NZ_CP019458.1_4795522_4797526_+	pfam00535, Glycos_transf_2, Glycosyl transferase family 2
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	9	5555241-5555489	3	CRT	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	GAGGGCTGATCCTGCGGC	18	4	7	5555301-5555318|5555301-5555318|5555337-5555354|5555337-5555354|5555373-5555390|5555373-5555390|5555409-5555426	NZ_CP019458.1_2509074-2509091|NZ_CP019458.1_6456767-6456750|NZ_CP019458.1_1534091-1534108|NZ_CP019458.1_7358142-7358125|NZ_CP019458.1_1215314-1215331|NZ_CP019458.1_7677539-7677522|NZ_CP019458.1_3626728-3626745	NA	6	6	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|56aa|up_2|NZ_CP019458.1_5553166_5553334_+,NA|55aa|down_2|NZ_CP019458.1_5558925_5559090_+	NA|316aa|up_9|NZ_CP019458.1_5546224_5547172_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|138aa|up_8|NZ_CP019458.1_5547175_5547589_-	pfam03965, Penicillinase_R, Penicillinase repressor	NA|427aa|up_7|NZ_CP019458.1_5547776_5549057_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|508aa|up_6|NZ_CP019458.1_5549099_5550623_-	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2	NA|100aa|up_5|NZ_CP019458.1_5551066_5551366_+	COG5450, COG5450, Transcription regulator of the Arc/MetJ class [Transcription]	NA|235aa|up_4|NZ_CP019458.1_5551503_5552208_+	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator	NA|212aa|up_3|NZ_CP019458.1_5552348_5552984_-	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed	NA|56aa|up_2|NZ_CP019458.1_5553166_5553334_+	NA	NA|179aa|up_1|NZ_CP019458.1_5553515_5554052_+	TIGR03941, conserved_hypothetical_protein, putative tRNA adenosine deaminase-associated protein	NA|167aa|up_0|NZ_CP019458.1_5554235_5554736_+	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|295aa|down_0|NZ_CP019458.1_5556766_5557651_+	pfam00582, Usp, Universal stress protein family	NA|342aa|down_1|NZ_CP019458.1_5557661_5558687_-	TIGR02483, ATP-dependent_6-phosphofructokinase_1, phosphofructokinase	NA|55aa|down_2|NZ_CP019458.1_5558925_5559090_+	NA	NA|278aa|down_3|NZ_CP019458.1_5559252_5560086_+	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily	NA|277aa|down_4|NZ_CP019458.1_5560273_5561104_+	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily	NA|276aa|down_5|NZ_CP019458.1_5561169_5561997_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|68aa|down_6|NZ_CP019458.1_5562065_5562269_-	TIGR00198, cat_per_HPI, catalase/peroxidase HPI	NA|163aa|down_7|NZ_CP019458.1_5562482_5562971_+	COG1846, MarR, Transcriptional regulators [Transcription]	NA|872aa|down_8|NZ_CP019458.1_5562979_5565595_+	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|284aa|down_9|NZ_CP019458.1_5565948_5566800_+	pfam04264, YceI, YceI-like domain
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	10	5677186-5677405	4	CRT	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	CACAGAACCTGCCCGACACCCA	22	1	1	5677341-5677383	NZ_CP019458.1_5677143-5677185	NA	3	3	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|195aa|up_5|NZ_CP019458.1_5669940_5670525_-,NA|283aa|down_6|NZ_CP019458.1_5688236_5689085_+	NA|243aa|up_9|NZ_CP019458.1_5666000_5666729_-	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]	NA|309aa|up_8|NZ_CP019458.1_5666744_5667671_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|300aa|up_7|NZ_CP019458.1_5667667_5668567_-	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein	NA|360aa|up_6|NZ_CP019458.1_5668556_5669636_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|195aa|up_5|NZ_CP019458.1_5669940_5670525_-	NA	NA|303aa|up_4|NZ_CP019458.1_5670528_5671437_-	PRK02391, PRK02391, heat shock protein HtpX; Provisional	NA|303aa|up_3|NZ_CP019458.1_5671561_5672470_-	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family	NA|297aa|up_2|NZ_CP019458.1_5672740_5673631_+	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily	NA|282aa|up_1|NZ_CP019458.1_5673720_5674566_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|565aa|up_0|NZ_CP019458.1_5675251_5676946_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|1262aa|down_0|NZ_CP019458.1_5677406_5681192_-	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit	NA|334aa|down_1|NZ_CP019458.1_5681211_5682213_-	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II	NA|530aa|down_2|NZ_CP019458.1_5682239_5683829_-	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I	NA|360aa|down_3|NZ_CP019458.1_5684032_5685112_-	PRK03321, PRK03321, putative aminotransferase; Provisional	NA|367aa|down_4|NZ_CP019458.1_5685516_5686617_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|404aa|down_5|NZ_CP019458.1_5686833_5688045_+	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain	NA|283aa|down_6|NZ_CP019458.1_5688236_5689085_+	NA	NA|291aa|down_7|NZ_CP019458.1_5689221_5690094_+	pfam02498, Bro-N, BRO family, N-terminal domain	NA|588aa|down_8|NZ_CP019458.1_5690227_5691991_-	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional	NA|484aa|down_9|NZ_CP019458.1_5692171_5693623_+	pfam07907, YibE_F, YibE/F-like protein
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	11	6016065-6016164	9	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	GAACCCTCCACGGGAGCGCGGCC	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|337aa|up_0|NZ_CP019458.1_6013557_6014568_-,NA|217aa|down_4|NZ_CP019458.1_6023662_6024313_+,NA|500aa|down_8|NZ_CP019458.1_6030156_6031656_+	NA|286aa|up_9|NZ_CP019458.1_6002910_6003768_+	TIGR03036, trp_2_3_diox, tryptophan 2,3-dioxygenase	NA|402aa|up_8|NZ_CP019458.1_6004003_6005209_+	COG3844, COG3844, Kynureninase [Amino acid transport and metabolism]	NA|350aa|up_7|NZ_CP019458.1_6005212_6006262_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|499aa|up_6|NZ_CP019458.1_6006400_6007897_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|242aa|up_5|NZ_CP019458.1_6007893_6008619_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|408aa|up_4|NZ_CP019458.1_6008646_6009870_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|551aa|up_3|NZ_CP019458.1_6010100_6011753_-	COG3559, TnrB3, Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane]	NA|306aa|up_2|NZ_CP019458.1_6011749_6012667_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|179aa|up_1|NZ_CP019458.1_6012759_6013296_+	COG1510, COG1510, Predicted transcriptional regulators [Transcription]	NA|337aa|up_0|NZ_CP019458.1_6013557_6014568_-	NA	NA|602aa|down_0|NZ_CP019458.1_6016179_6017985_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|942aa|down_1|NZ_CP019458.1_6018036_6020862_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|454aa|down_2|NZ_CP019458.1_6021168_6022530_+	PRK06062, PRK06062, hypothetical protein; Provisional	NA|240aa|down_3|NZ_CP019458.1_6022731_6023451_+	COG1802, GntR, Transcriptional regulators [Transcription]	NA|217aa|down_4|NZ_CP019458.1_6023662_6024313_+	NA	NA|245aa|down_5|NZ_CP019458.1_6024494_6025229_-	pfam18183, SLATT_2, SMODS and SLOG-associating 2TM effector domain 2	NA|422aa|down_6|NZ_CP019458.1_6026303_6027569_+	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional	NA|637aa|down_7|NZ_CP019458.1_6027945_6029856_+	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase	NA|500aa|down_8|NZ_CP019458.1_6030156_6031656_+	NA	NA|485aa|down_9|NZ_CP019458.1_6031927_6033382_-	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	12	6663829-6663916	10	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	AGCCACCCGCGTCCGCGCGAACGACAC	27	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|63aa|up_3|NZ_CP019458.1_6661292_6661481_+,NA	NA|254aa|up_9|NZ_CP019458.1_6654357_6655119_+	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]	NA|315aa|up_8|NZ_CP019458.1_6655115_6656060_+	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family	NA|696aa|up_7|NZ_CP019458.1_6656145_6658233_+	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional	NA|359aa|up_6|NZ_CP019458.1_6658240_6659317_-	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]	NA|381aa|up_5|NZ_CP019458.1_6659401_6660544_-	cd02252, nylC_like, nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC	NA|192aa|up_4|NZ_CP019458.1_6660713_6661289_+	cd05966, ACS, Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme)	NA|63aa|up_3|NZ_CP019458.1_6661292_6661481_+	NA	NA|156aa|up_2|NZ_CP019458.1_6661488_6661956_-	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL	NA|230aa|up_1|NZ_CP019458.1_6662088_6662778_-	pfam16976, RcpC, Flp pilus assembly protein RcpC/CpaB	NA|282aa|up_0|NZ_CP019458.1_6662971_6663817_-	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|125aa|down_0|NZ_CP019458.1_6663976_6664351_-	COG2331, COG2331, Uncharacterized protein conserved in bacteria [Function unknown]	NA|502aa|down_1|NZ_CP019458.1_6664496_6666002_-	PRK05326, PRK05326, potassium/proton antiporter	NA|921aa|down_2|NZ_CP019458.1_6666237_6669000_+	COG2366, COG2366, Protein related to penicillin acylase [General function prediction only]	NA|201aa|down_3|NZ_CP019458.1_6669142_6669745_-	pfam01812, 5-FTHF_cyc-lig, 5-formyltetrahydrofolate cyclo-ligase family	NA|301aa|down_4|NZ_CP019458.1_6669827_6670730_+	cd02541, UGPase_prokaryotic, Prokaryotic UGPase catalyses the synthesis of UDP-glucose	NA|440aa|down_5|NZ_CP019458.1_6670734_6672054_+	cd00887, MoeA, MoeA family	NA|161aa|down_6|NZ_CP019458.1_6672119_6672602_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|193aa|down_7|NZ_CP019458.1_6672598_6673177_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|208aa|down_8|NZ_CP019458.1_6673173_6673797_+	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]	NA|409aa|down_9|NZ_CP019458.1_6673939_6675166_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	13	6805687-6805793	11	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	TGGGCTGACGCGGCTCTGGGGCAGGC	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|303aa|up_9|NZ_CP019458.1_6791679_6792588_+,NA|490aa|up_7|NZ_CP019458.1_6793473_6794943_-,NA|166aa|up_6|NZ_CP019458.1_6795049_6795547_-,NA|163aa|up_5|NZ_CP019458.1_6795605_6796094_-,NA|178aa|up_3|NZ_CP019458.1_6800947_6801481_+,NA|366aa|up_0|NZ_CP019458.1_6803289_6804387_-,NA|85aa|down_0|NZ_CP019458.1_6805867_6806122_-,NA|83aa|down_8|NZ_CP019458.1_6813439_6813688_+	NA|303aa|up_9|NZ_CP019458.1_6791679_6792588_+	NA	NA|250aa|up_8|NZ_CP019458.1_6792654_6793404_-	pfam10138, vWA-TerF-like, vWA found in TerF C-terminus	NA|490aa|up_7|NZ_CP019458.1_6793473_6794943_-	NA	NA|166aa|up_6|NZ_CP019458.1_6795049_6795547_-	NA	NA|163aa|up_5|NZ_CP019458.1_6795605_6796094_-	NA	NA|351aa|up_4|NZ_CP019458.1_6796381_6797434_-	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only]	NA|178aa|up_3|NZ_CP019458.1_6800947_6801481_+	NA	NA|200aa|up_2|NZ_CP019458.1_6801847_6802447_+	pfam04978, DUF664, Protein of unknown function (DUF664)	NA|220aa|up_1|NZ_CP019458.1_6802491_6803151_-	PRK00058, PRK00058, peptide-methionine (S)-S-oxide reductase MsrA	NA|366aa|up_0|NZ_CP019458.1_6803289_6804387_-	NA	NA|85aa|down_0|NZ_CP019458.1_6805867_6806122_-	NA	NA|161aa|down_1|NZ_CP019458.1_6806870_6807353_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|473aa|down_2|NZ_CP019458.1_6807644_6809063_+	PRK08198, PRK08198, threonine dehydratase; Provisional	NA|359aa|down_3|NZ_CP019458.1_6809355_6810432_+	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit	NA|288aa|down_4|NZ_CP019458.1_6810431_6811295_+	pfam01061, ABC2_membrane, ABC-2 type transporter	NA|166aa|down_5|NZ_CP019458.1_6811370_6811868_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|135aa|down_6|NZ_CP019458.1_6812057_6812462_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|291aa|down_7|NZ_CP019458.1_6812559_6813432_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|83aa|down_8|NZ_CP019458.1_6813439_6813688_+	NA	NA|1096aa|down_9|NZ_CP019458.1_6813766_6817054_-	sd00006, TPR, Tetratricopeptide repeat
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	14	6917809-6918369	4,12,5	PILER-CR,CRISPRCasFinder,CRT	no	cas2	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Unclear	GTCCTCATCAGCCCTGGAGGGCTG,GTCCTCATCAGCCCTGGAGGGCTGGCAAC,GTCCTCATCAGCCCTGGAGGGCTGGCAAC	24,29,29	0	0	NA	NA	NA:NA:NA	7,7,8	8	Unclear	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|223aa|up_2|NZ_CP019458.1_6913270_6913939_-,NA|117aa|down_7|NZ_CP019458.1_6926267_6926618_+,NA|146aa|down_8|NZ_CP019458.1_6926889_6927327_-	NA|344aa|up_9|NZ_CP019458.1_6907194_6908226_-	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed	NA|180aa|up_8|NZ_CP019458.1_6908380_6908920_+	pfam14030, DUF4245, Protein of unknown function (DUF4245)	NA|197aa|up_7|NZ_CP019458.1_6908990_6909581_-	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|107aa|up_6|NZ_CP019458.1_6909937_6910258_-	PRK00977, PRK00977, exodeoxyribonuclease VII small subunit; Provisional	NA|407aa|up_5|NZ_CP019458.1_6910268_6911489_-	TIGR00237, exodeoxyribonuclease_VII_large_subunit, exodeoxyribonuclease VII, large subunit	NA|342aa|up_4|NZ_CP019458.1_6911551_6912577_+	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed	NA|250aa|up_3|NZ_CP019458.1_6912615_6913365_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|223aa|up_2|NZ_CP019458.1_6913270_6913939_-	NA	NA|363aa|up_1|NZ_CP019458.1_6914137_6915226_+	PRK09601, PRK09601, redox-regulated ATPase YchF	cas2|88aa|up_0|NZ_CP019458.1_6917445_6917709_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|61aa|down_0|NZ_CP019458.1_6918926_6919109_+	pfam12728, HTH_17, Helix-turn-helix domain	NA|165aa|down_1|NZ_CP019458.1_6919840_6920335_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|777aa|down_2|NZ_CP019458.1_6920748_6923079_-	pfam02687, FtsX, FtsX-like permease family	NA|229aa|down_3|NZ_CP019458.1_6923237_6923924_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|175aa|down_4|NZ_CP019458.1_6923920_6924445_-	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|78aa|down_5|NZ_CP019458.1_6924532_6924766_-	COG4877, COG4877, Uncharacterized protein conserved in bacteria [Function unknown]	NA|284aa|down_6|NZ_CP019458.1_6925094_6925946_+	COG0824, FcbC, Predicted thioesterase [General function prediction only]	NA|117aa|down_7|NZ_CP019458.1_6926267_6926618_+	NA	NA|146aa|down_8|NZ_CP019458.1_6926889_6927327_-	NA	NA|187aa|down_9|NZ_CP019458.1_6927846_6928407_+	pfam04229, GrpB, GrpB protein
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	15	7055466-7055546	13	CRISPRCasFinder	no	Cas14u_CAS-V	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Unclear	GTCCGCCACCGCGTCCTCCGAGCGGTCCGC	30	0	0	NA	NA	NA	1	1	Unclear	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|284aa|up_1|NZ_CP019458.1_7052480_7053332_-,NA|95aa|up_0|NZ_CP019458.1_7053410_7053695_-,NA|120aa|down_6|NZ_CP019458.1_7065298_7065658_-	NA|343aa|up_9|NZ_CP019458.1_7041353_7042382_+	COG3001, COG3001, Uncharacterized protein conserved in bacteria [Function unknown]	NA|251aa|up_8|NZ_CP019458.1_7042514_7043267_+	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|543aa|up_7|NZ_CP019458.1_7043536_7045165_+	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]	NA|62aa|up_6|NZ_CP019458.1_7045332_7045518_+	PRK10672, PRK10672, endolytic peptidoglycan transglycosylase RlpA	NA|145aa|up_5|NZ_CP019458.1_7045763_7046198_+	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi)	NA|900aa|up_4|NZ_CP019458.1_7046444_7049144_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|257aa|up_3|NZ_CP019458.1_7049742_7050513_-	PRK12386, PRK12386, fumarate reductase iron-sulfur subunit; Provisional	NA|652aa|up_2|NZ_CP019458.1_7050509_7052465_-	PRK07803, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed	NA|284aa|up_1|NZ_CP019458.1_7052480_7053332_-	NA	NA|95aa|up_0|NZ_CP019458.1_7053410_7053695_-	NA	NA|632aa|down_0|NZ_CP019458.1_7056747_7058643_+	TIGR01394, GTP-binding_protein_TypA/BipA_homolog, GTP-binding protein TypA/BipA	NA|548aa|down_1|NZ_CP019458.1_7059264_7060908_+	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|309aa|down_2|NZ_CP019458.1_7061056_7061983_+	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|327aa|down_3|NZ_CP019458.1_7061975_7062956_+	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|353aa|down_4|NZ_CP019458.1_7062967_7064026_+	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|386aa|down_5|NZ_CP019458.1_7064018_7065176_+	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional	NA|120aa|down_6|NZ_CP019458.1_7065298_7065658_-	NA	NA|143aa|down_7|NZ_CP019458.1_7065872_7066301_-	pfam01797, Y1_Tnp, Transposase IS200 like	Cas14u_CAS-V|387aa|down_8|NZ_CP019458.1_7066324_7067485_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|145aa|down_9|NZ_CP019458.1_7067567_7068002_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	16	7493095-7493365	6	CRT	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	GCGCCNAGCGGGTCGGTGA	19	0	0	NA	NA	NA	4	4	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA|103aa|up_4|NZ_CP019458.1_7485320_7485629_-,NA|462aa|up_2|NZ_CP019458.1_7486866_7488252_-,NA|140aa|up_0|NZ_CP019458.1_7490526_7490946_-,NA|241aa|down_0|NZ_CP019458.1_7496340_7497063_-,NA|112aa|down_3|NZ_CP019458.1_7499868_7500204_+	NA|381aa|up_9|NZ_CP019458.1_7480807_7481950_+	pfam17964, Big_10, Bacterial Ig domain	NA|256aa|up_8|NZ_CP019458.1_7482106_7482874_+	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|168aa|up_7|NZ_CP019458.1_7483151_7483655_+	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|209aa|up_6|NZ_CP019458.1_7484165_7484792_+	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase	NA|77aa|up_5|NZ_CP019458.1_7484999_7485230_+	cd00051, EFh, EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands	NA|103aa|up_4|NZ_CP019458.1_7485320_7485629_-	NA	NA|214aa|up_3|NZ_CP019458.1_7485674_7486316_-	pfam01183, Glyco_hydro_25, Glycosyl hydrolases family 25	NA|462aa|up_2|NZ_CP019458.1_7486866_7488252_-	NA	NA|449aa|up_1|NZ_CP019458.1_7488557_7489904_+	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]	NA|140aa|up_0|NZ_CP019458.1_7490526_7490946_-	NA	NA|241aa|down_0|NZ_CP019458.1_7496340_7497063_-	NA	NA|187aa|down_1|NZ_CP019458.1_7497157_7497718_+	COG1846, MarR, Transcriptional regulators [Transcription]	NA|677aa|down_2|NZ_CP019458.1_7497811_7499842_+	pfam13367, PrsW-protease, Protease prsW family	NA|112aa|down_3|NZ_CP019458.1_7499868_7500204_+	NA	NA|285aa|down_4|NZ_CP019458.1_7500515_7501370_-	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional	NA|186aa|down_5|NZ_CP019458.1_7501366_7501924_-	COG2128, COG2128, Uncharacterized conserved protein [Function unknown]	NA|461aa|down_6|NZ_CP019458.1_7502071_7503454_-	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form	NA|422aa|down_7|NZ_CP019458.1_7503642_7504908_-	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|127aa|down_8|NZ_CP019458.1_7504933_7505314_-	PRK01202, PRK01202, glycine cleavage system protein GcvH	NA|376aa|down_9|NZ_CP019458.1_7505486_7506614_-	PRK00389, gcvT, glycine cleavage system aminomethyltransferase GcvT
GCF_001983975.1_ASM198397v1	NZ_CP019458	Streptomyces autolyticus strain CGMCC0516 chromosome, complete genome	17	7539392-7539540	14	CRISPRCasFinder	no		WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	Orphan	GTTGAAAGCCGCACCTCTGCGCCGCGCGGGCGGAGAAGCGAACGGAGAGACGCC	54	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,casR,cas4,DEDDh,Cas14u_CAS-V,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,PD-DExK,DinG,RT	NA,NA|78aa|down_3|NZ_CP019458.1_7546214_7546448_+,NA|59aa|down_5|NZ_CP019458.1_7549933_7550110_-	NA|493aa|up_9|NZ_CP019458.1_7525888_7527367_+	PLN02244, PLN02244, tocopherol O-methyltransferase	NA|350aa|up_8|NZ_CP019458.1_7527470_7528520_-	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators	NA|460aa|up_7|NZ_CP019458.1_7528523_7529903_+	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins	NA|176aa|up_6|NZ_CP019458.1_7530143_7530671_+	pfam03641, Lysine_decarbox, Possible lysine decarboxylase	NA|230aa|up_5|NZ_CP019458.1_7530814_7531504_+	PRK08219, PRK08219, SDR family oxidoreductase	NA|318aa|up_4|NZ_CP019458.1_7531764_7532718_+	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE	NA|741aa|up_3|NZ_CP019458.1_7532733_7534956_+	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated	NA|704aa|up_2|NZ_CP019458.1_7535247_7537359_+	cd01948, EAL, EAL domain	NA|99aa|up_1|NZ_CP019458.1_7537561_7537858_+	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA|498aa|up_0|NZ_CP019458.1_7537863_7539357_+	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA|502aa|down_0|NZ_CP019458.1_7539794_7541300_+	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA|497aa|down_1|NZ_CP019458.1_7542153_7543644_-	pfam07364, DUF1485, Metallopeptidase family M81	NA|775aa|down_2|NZ_CP019458.1_7543772_7546097_+	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only]	NA|78aa|down_3|NZ_CP019458.1_7546214_7546448_+	NA	NA|1046aa|down_4|NZ_CP019458.1_7546650_7549788_+	COG3899, COG3899, Predicted ATPase [General function prediction only]	NA|59aa|down_5|NZ_CP019458.1_7549933_7550110_-	NA	NA|398aa|down_6|NZ_CP019458.1_7550224_7551418_-	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase	NA|333aa|down_7|NZ_CP019458.1_7551738_7552737_-	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR)	NA|313aa|down_8|NZ_CP019458.1_7552873_7553812_+	cd12166, 2-Hacid_dh_7, Putative D-isomer specific 2-hydroxyacid dehydrogenases	NA|972aa|down_9|NZ_CP019458.1_7554158_7557074_+	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase
