assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001901085.1_ASM190108v1	NZ_CP010191	Escherichia coli strain M8 chromosome, complete genome	1	344128-344275	1	CRISPRCasFinder	no		DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	Orphan	CGCGAGCGCCTTATCCGACCTACGGTTCAGACCTGTAGGCATGATAAGACGCG	53	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	NA,NA|82aa|down_7|NZ_CP010191.1_353190_353436_-,NA|272aa|down_8|NZ_CP010191.1_353848_354664_-	NA|361aa|up_9|NZ_CP010191.1_331325_332408_+	PRK09526, lacI, lac repressor; Reviewed	NA|1025aa|up_8|NZ_CP010191.1_332530_335605_+	PRK09525, lacZ, beta-galactosidase	NA|418aa|up_7|NZ_CP010191.1_335656_336910_+	PRK09528, lacY, galactoside permease; Reviewed	NA|204aa|up_6|NZ_CP010191.1_336975_337587_+	PRK09527, lacA, galactoside O-acetyltransferase; Reviewed	NA|394aa|up_5|NZ_CP010191.1_337689_338871_-	PRK09705, cynX, putative cyanate transporter; Provisional	NA|157aa|up_4|NZ_CP010191.1_338876_339347_-	COG1513, CynS, Cyanate lyase [Inorganic ion transport and metabolism]	NA|220aa|up_3|NZ_CP010191.1_339377_340037_-	cd00884, beta_CA_cladeB, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site	NA|300aa|up_2|NZ_CP010191.1_340146_341046_+	PRK11242, PRK11242, DNA-binding transcriptional regulator CynR; Provisional	NA|428aa|up_1|NZ_CP010191.1_341382_342666_-	PRK09230, PRK09230, cytosine deaminase; Provisional	NA|420aa|up_0|NZ_CP010191.1_342655_343915_-	PRK11017, codB, cytosine permease; Provisional	NA|629aa|down_0|NZ_CP010191.1_344340_346227_-	PRK10524, prpE, propionyl-CoA synthetase; Provisional	NA|484aa|down_1|NZ_CP010191.1_346266_347718_-	PRK09425, prpD, bifunctional 2-methylcitrate dehydratase/aconitate hydratase	NA|390aa|down_2|NZ_CP010191.1_347751_348921_-	PRK12351, PRK12351, methylcitrate synthase; Provisional	NA|297aa|down_3|NZ_CP010191.1_349267_350158_-	PRK11320, prpB, 2-methylisocitrate lyase; Provisional	NA|529aa|down_4|NZ_CP010191.1_350396_351983_+	PRK15424, PRK15424, propionate catabolism operon regulatory protein PrpR; Provisional	NA|92aa|down_5|NZ_CP010191.1_352080_352356_-	PRK09929, PRK09929, hypothetical protein; Provisional	NA|224aa|down_6|NZ_CP010191.1_352502_353174_+	TIGR00949, Uncharacterized_membrane_protein_YahN, The Resistance to Homoserine/Threonine (RhtB) Family protein	NA|82aa|down_7|NZ_CP010191.1_353190_353436_-	NA	NA|272aa|down_8|NZ_CP010191.1_353848_354664_-	NA	NA|350aa|down_9|NZ_CP010191.1_354906_355956_-	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD)
GCF_001901085.1_ASM190108v1	NZ_CP010191	Escherichia coli strain M8 chromosome, complete genome	2	2162315-2162432	2	CRISPRCasFinder	no		DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	Orphan	TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	40	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	NA,NA|55aa|down_0|NZ_CP010191.1_2162505_2162670_-	NA|115aa|up_9|NZ_CP010191.1_2150036_2150381_-	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional	NA|313aa|up_8|NZ_CP010191.1_2150569_2151508_+	PRK10341, PRK10341, transcriptional regulator TdcA	NA|330aa|up_7|NZ_CP010191.1_2151606_2152596_+	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA|444aa|up_6|NZ_CP010191.1_2152617_2153949_+	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional	NA|403aa|up_5|NZ_CP010191.1_2153974_2155183_+	PRK12379, PRK12379, propionate kinase	NA|765aa|up_4|NZ_CP010191.1_2155216_2157511_+	cd01678, PFL1, Pyruvate formate lyase 1	NA|130aa|up_3|NZ_CP010191.1_2157524_2157914_+	PRK11401, PRK11401, enamine/imine deaminase	NA|455aa|up_2|NZ_CP010191.1_2157985_2159350_+	PRK15040, PRK15040, L-serine ammonia-lyase	NA|444aa|up_1|NZ_CP010191.1_2159624_2160956_+	TIGR00814, membrane_transport_protein_YhjV, serine transporter	NA|437aa|up_0|NZ_CP010191.1_2160983_2162294_+	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|55aa|down_0|NZ_CP010191.1_2162505_2162670_-	NA	NA|234aa|down_1|NZ_CP010191.1_2162692_2163394_-	COG1741, COG1741, Pirin-related protein [General function prediction only]	NA|299aa|down_2|NZ_CP010191.1_2163498_2164395_+	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold	NA|119aa|down_3|NZ_CP010191.1_2164445_2164802_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|122aa|down_4|NZ_CP010191.1_2165043_2165409_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|329aa|down_5|NZ_CP010191.1_2165701_2166688_-	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]	NA|131aa|down_6|NZ_CP010191.1_2166757_2167150_-	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|100aa|down_7|NZ_CP010191.1_2167335_2167635_-	pfam13997, YqjK, YqjK-like protein	NA|135aa|down_8|NZ_CP010191.1_2167624_2168029_-	COG5393, COG5393, Predicted membrane protein [Function unknown]	NA|102aa|down_9|NZ_CP010191.1_2168031_2168337_-	COG4575, ElaB, Uncharacterized conserved protein [Function unknown]
GCF_001901085.1_ASM190108v1	NZ_CP010191	Escherichia coli strain M8 chromosome, complete genome	3	2564359-2565180	3,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas3	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	Unclear	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,TCCCCGCGCCAGCGGGGATAAACCG	29,29,25	0	0	NA	NA	I-E:I-E:I-E	13,13,13	13	Unclear	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	NA|47aa|up_1|NZ_CP010191.1_2563068_2563209_-,NA	NA|919aa|up_9|NZ_CP010191.1_2550952_2553709_-	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional	NA|434aa|up_8|NZ_CP010191.1_2553765_2555067_+	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	NA|745aa|up_7|NZ_CP010191.1_2555114_2557349_+	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|83aa|up_6|NZ_CP010191.1_2557426_2557675_+	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|112aa|up_5|NZ_CP010191.1_2557674_2558010_+	PRK09907, PRK09907, endoribonuclease MazF	NA|264aa|up_4|NZ_CP010191.1_2558080_2558872_+	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|546aa|up_3|NZ_CP010191.1_2559099_2560737_+	PRK05380, pyrG, CTP synthetase; Validated	NA|433aa|up_2|NZ_CP010191.1_2560824_2562123_+	PRK00077, eno, enolase; Provisional	NA|47aa|up_1|NZ_CP010191.1_2563068_2563209_-	NA	NA|224aa|up_0|NZ_CP010191.1_2563347_2564019_+	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|493aa|down_0|NZ_CP010191.1_2565818_2567297_-	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|426aa|down_1|NZ_CP010191.1_2567323_2568601_-	cd06174, MFS, Major Facilitator Superfamily	NA|262aa|down_2|NZ_CP010191.1_2568919_2569705_+	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|485aa|down_3|NZ_CP010191.1_2569774_2571229_+	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|470aa|down_4|NZ_CP010191.1_2571250_2572660_+	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|260aa|down_5|NZ_CP010191.1_2572637_2573417_+	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|287aa|down_6|NZ_CP010191.1_2573413_2574274_+	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|192aa|down_7|NZ_CP010191.1_2574421_2574997_-	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|87aa|down_8|NZ_CP010191.1_2575013_2575274_-	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|424aa|down_9|NZ_CP010191.1_2575264_2576536_-	PRK10015, PRK10015, oxidoreductase; Provisional
GCF_001901085.1_ASM190108v1	NZ_CP010191	Escherichia coli strain M8 chromosome, complete genome	4	2590879-2592250	2,4,2	PILER-CR,CRISPRCasFinder,CRT	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	Type I-E	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	0	0	NA	NA	I-E:I-E:I-E	22,22,22	22	TypeI-E	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	NA,NA	NA|245aa|up_9|NZ_CP010191.1_2580878_2581613_+	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|51aa|up_8|NZ_CP010191.1_2581877_2582030_+	pfam01848, HOK_GEF, Hok/gef family	cas3|900aa|up_7|NZ_CP010191.1_2582223_2584923_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas8e|521aa|up_6|NZ_CP010191.1_2585020_2586583_+	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1	cse2gr11|179aa|up_5|NZ_CP010191.1_2586579_2587116_+	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2	cas7|352aa|up_4|NZ_CP010191.1_2587127_2588183_+	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cas5|249aa|up_3|NZ_CP010191.1_2588193_2588940_+	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas6e|217aa|up_2|NZ_CP010191.1_2588921_2589572_+	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas1|308aa|up_1|NZ_CP010191.1_2589568_2590492_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|98aa|up_0|NZ_CP010191.1_2590488_2590782_+	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	NA|346aa|down_0|NZ_CP010191.1_2592331_2593369_-	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	NA|303aa|down_1|NZ_CP010191.1_2593620_2594529_+	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|476aa|down_2|NZ_CP010191.1_2594530_2595958_+	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|202aa|down_3|NZ_CP010191.1_2595957_2596563_+	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|108aa|down_4|NZ_CP010191.1_2596612_2596936_+	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|104aa|down_5|NZ_CP010191.1_2597129_2597441_+	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|237aa|down_6|NZ_CP010191.1_2597459_2598170_+	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|160aa|down_7|NZ_CP010191.1_2598169_2598649_+	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|350aa|down_8|NZ_CP010191.1_2598645_2599695_+	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|254aa|down_9|NZ_CP010191.1_2599675_2600437_+	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional
GCF_001901085.1_ASM190108v1	NZ_CP010191	Escherichia coli strain M8 chromosome, complete genome	5	3696536-3696659	5	CRISPRCasFinder	no	DEDDh	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	Unclear	CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	43	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	NA,NA|30aa|down_7|NZ_CP010191.1_3705555_3705645_+	NA|471aa|up_9|NZ_CP010191.1_3685989_3687402_-	PRK09206, PRK09206, pyruvate kinase PykF	NA|70aa|up_8|NZ_CP010191.1_3687958_3688168_+	PRK10292, PRK10292, fumarate hydratase FumD	NA|209aa|up_7|NZ_CP010191.1_3688623_3689250_+	PRK09898, PRK09898, ferredoxin-like protein	NA|701aa|up_6|NZ_CP010191.1_3689270_3691373_+	PRK09849, PRK09849, putative oxidoreductase; Provisional	NA|213aa|up_5|NZ_CP010191.1_3691385_3692024_+	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein	NA|223aa|up_4|NZ_CP010191.1_3692087_3692756_+	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein	NA|262aa|up_3|NZ_CP010191.1_3692752_3693538_+	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional	NA|271aa|up_2|NZ_CP010191.1_3693541_3694354_+	PRK09946, PRK09946, hypothetical protein; Provisional	NA|535aa|up_1|NZ_CP010191.1_3694365_3695970_-	PRK09897, PRK09897, FAD-NAD(P)-binding protein	NA|102aa|up_0|NZ_CP010191.1_3696095_3696401_-	PRK11118, PRK11118, putative monooxygenase; Provisional	NA|419aa|down_0|NZ_CP010191.1_3696973_3698230_+	PRK09945, PRK09945, hypothetical protein; Provisional	NA|458aa|down_1|NZ_CP010191.1_3698270_3699644_-	PRK01766, PRK01766, multidrug efflux protein; Reviewed	NA|214aa|down_2|NZ_CP010191.1_3699858_3700500_+	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional	NA|383aa|down_3|NZ_CP010191.1_3700539_3701688_-	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase	NA|404aa|down_4|NZ_CP010191.1_3701978_3703190_-	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter	NA|311aa|down_5|NZ_CP010191.1_3703302_3704235_+	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional	NA|342aa|down_6|NZ_CP010191.1_3704231_3705257_-	PRK10703, PRK10703, HTH-type transcriptional repressor PurR	NA|30aa|down_7|NZ_CP010191.1_3705555_3705645_+	NA	NA|390aa|down_8|NZ_CP010191.1_3705810_3706980_+	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|194aa|down_9|NZ_CP010191.1_3707125_3707707_-	PRK10543, PRK10543, superoxide dismutase [Fe]
GCF_001901085.1_ASM190108v1	NZ_CP010191	Escherichia coli strain M8 chromosome, complete genome	6	4404221-4404312	6	CRISPRCasFinder	no		DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	Orphan	CCACCTTTTTTACCTGCTTCAGATGC	26	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,DinG	NA|70aa|up_9|NZ_CP010191.1_4393296_4393506_-,NA	NA|70aa|up_9|NZ_CP010191.1_4393296_4393506_-	NA	NA|1321aa|up_8|NZ_CP010191.1_4393560_4397523_+	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed	NA|213aa|up_7|NZ_CP010191.1_4397562_4398201_-	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional	NA|364aa|up_6|NZ_CP010191.1_4398488_4399580_+	TIGR03612, RutA, pyrimidine utilization protein A	NA|231aa|up_5|NZ_CP010191.1_4399579_4400272_+	TIGR03614, RutB, pyrimidine utilization protein B	NA|129aa|up_4|NZ_CP010191.1_4400283_4400670_+	TIGR03610, RutC, pyrimidine utilization protein C	NA|267aa|up_3|NZ_CP010191.1_4400677_4401478_+	TIGR03611, RutD, pyrimidine utilization protein D	NA|197aa|up_2|NZ_CP010191.1_4401487_4402078_+	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|165aa|up_1|NZ_CP010191.1_4402088_4402583_+	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F	NA|443aa|up_0|NZ_CP010191.1_4402603_4403932_+	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|199aa|down_0|NZ_CP010191.1_4404735_4405332_+	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|76aa|down_1|NZ_CP010191.1_4405352_4405580_+	PRK10174, PRK10174, hypothetical protein; Provisional	NA|414aa|down_2|NZ_CP010191.1_4405617_4406859_-	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional	NA|419aa|down_3|NZ_CP010191.1_4407151_4408408_-	PRK09784, PRK09784, YccE family protein	NA|307aa|down_4|NZ_CP010191.1_4408667_4409588_+	PRK10266, PRK10266, curved DNA-binding protein	NA|102aa|down_5|NZ_CP010191.1_4409587_4409893_+	PRK10265, PRK10265, chaperone modulator CbpM	NA|200aa|down_6|NZ_CP010191.1_4409985_4410585_-	PRK04976, torD, chaperone protein TorD; Validated	NA|849aa|down_7|NZ_CP010191.1_4410581_4413128_-	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA	NA|391aa|down_8|NZ_CP010191.1_4413127_4414300_-	PRK15032, PRK15032, pentaheme c-type cytochrome TorC	NA|231aa|down_9|NZ_CP010191.1_4414429_4415122_+	PRK10766, PRK10766, two-component system response regulator TorR
