assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	1	335015-335126	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGTTGCCGATCA	25	1	6	335085-335101|335085-335101|335085-335101|335085-335101|335085-335101|335085-335101	NZ_CP010337.1_843221-843205|NZ_CP010337.1_1193474-1193490|NZ_CP010337.1_1217384-1217368|NZ_CP010337.1_2432771-2432787|NZ_CP010337.1_2813045-2813061|NZ_CP010337.1_4026886-4026902	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP010337.1_333351_333534_-,NA	NA|398aa|up_9|NZ_CP010337.1_323529_324723_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP010337.1_324758_326441_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP010337.1_326457_328653_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP010337.1_328766_329900_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP010337.1_329896_330517_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP010337.1_330613_331195_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP010337.1_331124_331850_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP010337.1_331939_332860_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP010337.1_332899_333328_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP010337.1_333351_333534_-	NA	NA|900aa|down_0|NZ_CP010337.1_336677_339377_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP010337.1_342429_344040_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP010337.1_344063_344972_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP010337.1_345195_347091_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP010337.1_347087_348704_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP010337.1_348700_352693_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP010337.1_352689_352998_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP010337.1_353000_354542_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP010337.1_354590_354884_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP010337.1_354913_355204_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	2	341170-341392	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_CP010337.1_333351_333534_-,NA	NA|561aa|up_9|NZ_CP010337.1_324758_326441_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP010337.1_326457_328653_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP010337.1_328766_329900_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP010337.1_329896_330517_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP010337.1_330613_331195_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP010337.1_331124_331850_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP010337.1_331939_332860_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP010337.1_332899_333328_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP010337.1_333351_333534_-	NA	NA|900aa|up_0|NZ_CP010337.1_336677_339377_-	pfam00934, PE, PE family	NA|537aa|down_0|NZ_CP010337.1_342429_344040_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP010337.1_344063_344972_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP010337.1_345195_347091_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP010337.1_347087_348704_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP010337.1_348700_352693_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP010337.1_352689_352998_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP010337.1_353000_354542_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP010337.1_354590_354884_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP010337.1_354913_355204_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP010337.1_355214_356102_+	pfam14011, ESX-1_EspG, EspG family
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	3	369529-370227	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	369817-369858|369892-369924	NZ_CP010337.1_377848-377889|NZ_CP010337.1_376663-376695	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP010337.1_366541_366844_+,NA|161aa|down_1|NZ_CP010337.1_379637_380120_-,NA|410aa|down_5|NZ_CP010337.1_382236_383466_+	NA|262aa|up_9|NZ_CP010337.1_361236_362022_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP010337.1_362010_362814_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP010337.1_362823_364221_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP010337.1_364399_366175_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP010337.1_366317_366545_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP010337.1_366541_366844_+	NA	NA|74aa|up_3|NZ_CP010337.1_366891_367113_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP010337.1_367109_367535_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP010337.1_367670_368303_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP010337.1_368299_369208_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP010337.1_378978_379650_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP010337.1_379637_380120_-	NA	NA|239aa|down_2|NZ_CP010337.1_380177_380894_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP010337.1_380995_381652_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP010337.1_381721_382213_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP010337.1_382236_383466_+	NA	NA|621aa|down_6|NZ_CP010337.1_383620_385483_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP010337.1_385554_385941_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP010337.1_385943_386606_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP010337.1_386666_387551_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	4	693990-694066	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP010337.1_679674_679890_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP010337.1_679886_680294_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP010337.1_680353_681040_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP010337.1_681193_683827_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP010337.1_683849_686237_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP010337.1_686374_687097_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP010337.1_687093_687891_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP010337.1_687892_688780_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP010337.1_688785_690000_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP010337.1_691023_692469_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP010337.1_695201_696752_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP010337.1_696803_697196_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP010337.1_697192_697450_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP010337.1_697632_698868_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP010337.1_699118_699532_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP010337.1_699528_699765_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP010337.1_699868_700375_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP010337.1_700488_700959_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP010337.1_701002_701764_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP010337.1_701820_702132_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	5	1195200-1195308	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|394aa|up_9|NZ_CP010337.1_1183280_1184462_+	COG3391, COG3391, Uncharacterized conserved protein [Function unknown]	NA|544aa|up_8|NZ_CP010337.1_1184568_1186200_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_7|NZ_CP010337.1_1186275_1187340_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_6|NZ_CP010337.1_1187392_1187866_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_5|NZ_CP010337.1_1187899_1188763_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_4|NZ_CP010337.1_1188767_1189625_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_3|NZ_CP010337.1_1189625_1190708_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_2|NZ_CP010337.1_1190788_1191208_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_1|NZ_CP010337.1_1191319_1191886_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_0|NZ_CP010337.1_1191882_1192278_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|588aa|down_0|NZ_CP010337.1_1196392_1198156_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP010337.1_1198152_1198926_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP010337.1_1198937_1199975_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP010337.1_1200161_1200998_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP010337.1_1201113_1201965_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP010337.1_1202038_1203256_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP010337.1_1203308_1204253_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP010337.1_1204475_1205543_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP010337.1_1205599_1206994_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|389aa|down_9|NZ_CP010337.1_1207948_1209115_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	6	1576351-1577246	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1576551-1576572	NZ_CP010337.1_1215945-1215924	NA	12	12	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP010337.1_1568114_1568432_+,NA	NA|275aa|up_9|NZ_CP010337.1_1564611_1565436_+	PRK00125, pyrF, orotidine 5'-phosphate decarboxylase; Reviewed	NA|103aa|up_8|NZ_CP010337.1_1565630_1565939_+	pfam00934, PE, PE family	NA|106aa|up_7|NZ_CP010337.1_1568114_1568432_+	NA	NA|209aa|up_6|NZ_CP010337.1_1568566_1569193_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP010337.1_1569258_1569591_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP010337.1_1569606_1570863_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP010337.1_1570990_1572202_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP010337.1_1572274_1573753_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP010337.1_1573749_1575135_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP010337.1_1575212_1576247_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP010337.1_1578270_1578672_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP010337.1_1578668_1578926_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP010337.1_1579008_1579968_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP010337.1_1579992_1580955_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|656aa|down_4|NZ_CP010337.1_1581770_1583738_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_5|NZ_CP010337.1_1583755_1584580_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_6|NZ_CP010337.1_1584748_1585231_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_7|NZ_CP010337.1_1585302_1586127_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_8|NZ_CP010337.1_1586323_1587262_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed	NA|458aa|down_9|NZ_CP010337.1_1587258_1588632_+	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	7	1577336-1577421	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP010337.1_1568114_1568432_+,NA	NA|275aa|up_9|NZ_CP010337.1_1564611_1565436_+	PRK00125, pyrF, orotidine 5'-phosphate decarboxylase; Reviewed	NA|103aa|up_8|NZ_CP010337.1_1565630_1565939_+	pfam00934, PE, PE family	NA|106aa|up_7|NZ_CP010337.1_1568114_1568432_+	NA	NA|209aa|up_6|NZ_CP010337.1_1568566_1569193_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP010337.1_1569258_1569591_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP010337.1_1569606_1570863_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP010337.1_1570990_1572202_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP010337.1_1572274_1573753_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP010337.1_1573749_1575135_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP010337.1_1575212_1576247_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP010337.1_1578270_1578672_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP010337.1_1578668_1578926_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP010337.1_1579008_1579968_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP010337.1_1579992_1580955_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|656aa|down_4|NZ_CP010337.1_1581770_1583738_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_5|NZ_CP010337.1_1583755_1584580_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_6|NZ_CP010337.1_1584748_1585231_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_7|NZ_CP010337.1_1585302_1586127_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_8|NZ_CP010337.1_1586323_1587262_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed	NA|458aa|down_9|NZ_CP010337.1_1587258_1588632_+	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	8	2091035-2091289	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2091116-2091133|2091116-2091133|2091206-2091223	NZ_CP010337.1_404143-404126|NZ_CP010337.1_610457-610440|NZ_CP010337.1_3459185-3459168	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP010337.1_2090394_2090658_-,NA	NA|165aa|up_9|NZ_CP010337.1_2076801_2077296_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP010337.1_2077586_2078264_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP010337.1_2078622_2081448_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP010337.1_2081674_2082535_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP010337.1_2082575_2083442_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP010337.1_2083446_2085333_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP010337.1_2085348_2087382_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP010337.1_2087501_2089727_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP010337.1_2090002_2090398_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP010337.1_2090394_2090658_-	NA	NA|346aa|down_0|NZ_CP010337.1_2092426_2093464_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP010337.1_2093463_2094831_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP010337.1_2095004_2096441_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP010337.1_2096476_2097928_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP010337.1_2097957_2098908_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP010337.1_2098922_2099339_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP010337.1_2099616_2100039_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP010337.1_2100087_2100390_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP010337.1_2100386_2100701_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP010337.1_2100700_2102434_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	9	2171745-2171964	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP010337.1_2162713_2163121_-,NA|127aa|down_5|NZ_CP010337.1_2179480_2179861_-	NA|741aa|up_9|NZ_CP010337.1_2156681_2158904_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP010337.1_2158941_2159385_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP010337.1_2159498_2160092_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP010337.1_2160174_2160780_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP010337.1_2160879_2161884_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP010337.1_2161983_2162736_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP010337.1_2162713_2163121_-	NA	NA|368aa|up_2|NZ_CP010337.1_2163255_2164359_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP010337.1_2164358_2165555_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1506aa|up_0|NZ_CP010337.1_2165724_2170242_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP010337.1_2173991_2174456_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP010337.1_2174553_2175417_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP010337.1_2175454_2176726_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP010337.1_2176997_2178113_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP010337.1_2178103_2179444_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP010337.1_2179480_2179861_-	NA	NA|621aa|down_6|NZ_CP010337.1_2180017_2181880_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP010337.1_2181887_2182367_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP010337.1_2182603_2183377_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP010337.1_2183380_2184148_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	10	3125822-3127175	3,7,2	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-D,Type III-C,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGACN	36,36,37	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	15,17,18	18	TypeIII-B,TypeIII-D,TypeIII-C,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP010337.1_3119101_3119356_-,NA|135aa|up_7|NZ_CP010337.1_3119503_3119908_+,NA|64aa|up_6|NZ_CP010337.1_3119904_3120096_+,NA|86aa|up_4|NZ_CP010337.1_3121682_3121940_+,NA|104aa|up_3|NZ_CP010337.1_3122044_3122356_+,NA|203aa|up_2|NZ_CP010337.1_3122775_3123384_+,NA	NA|92aa|up_9|NZ_CP010337.1_3118650_3118926_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP010337.1_3119101_3119356_-	NA	NA|135aa|up_7|NZ_CP010337.1_3119503_3119908_+	NA	NA|64aa|up_6|NZ_CP010337.1_3119904_3120096_+	NA	NA|385aa|up_5|NZ_CP010337.1_3120294_3121449_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP010337.1_3121682_3121940_+	NA	NA|104aa|up_3|NZ_CP010337.1_3122044_3122356_+	NA	NA|203aa|up_2|NZ_CP010337.1_3122775_3123384_+	NA	NA|470aa|up_1|NZ_CP010337.1_3123454_3124864_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP010337.1_3124860_3125673_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP010337.1_3127201_3128463_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP010337.1_3130341_3130683_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP010337.1_3130683_3131700_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP010337.1_3131712_3132861_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP010337.1_3132956_3134084_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP010337.1_3134080_3134989_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP010337.1_3134969_3135680_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP010337.1_3135689_3136064_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP010337.1_3136060_3138499_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP010337.1_3138495_3139218_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	11	3128498-3130293	8,3,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-D,Type III-C,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	24,24,23	24	TypeIII-B,TypeIII-D,TypeIII-C,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP010337.1_3119101_3119356_-,NA|135aa|up_8|NZ_CP010337.1_3119503_3119908_+,NA|64aa|up_7|NZ_CP010337.1_3119904_3120096_+,NA|86aa|up_5|NZ_CP010337.1_3121682_3121940_+,NA|104aa|up_4|NZ_CP010337.1_3122044_3122356_+,NA|203aa|up_3|NZ_CP010337.1_3122775_3123384_+,NA	NA|85aa|up_9|NZ_CP010337.1_3119101_3119356_-	NA	NA|135aa|up_8|NZ_CP010337.1_3119503_3119908_+	NA	NA|64aa|up_7|NZ_CP010337.1_3119904_3120096_+	NA	NA|385aa|up_6|NZ_CP010337.1_3120294_3121449_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP010337.1_3121682_3121940_+	NA	NA|104aa|up_4|NZ_CP010337.1_3122044_3122356_+	NA	NA|203aa|up_3|NZ_CP010337.1_3122775_3123384_+	NA	NA|470aa|up_2|NZ_CP010337.1_3123454_3124864_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP010337.1_3124860_3125673_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP010337.1_3127201_3128463_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP010337.1_3130341_3130683_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP010337.1_3130683_3131700_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP010337.1_3131712_3132861_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP010337.1_3132956_3134084_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP010337.1_3134080_3134989_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP010337.1_3134969_3135680_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP010337.1_3135689_3136064_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP010337.1_3136060_3138499_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP010337.1_3138495_3139218_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP010337.1_3139617_3140163_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	12	3745683-3746362	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGNNNCCNCCGTNGCCGCC	23	0	0	NA	NA	NA	9	9	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_5|NZ_CP010337.1_3761762_3762050_-	NA|147aa|up_9|NZ_CP010337.1_3731546_3731987_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_8|NZ_CP010337.1_3732020_3732890_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_7|NZ_CP010337.1_3732910_3733921_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_6|NZ_CP010337.1_3734205_3734838_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_5|NZ_CP010337.1_3734904_3736134_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_4|NZ_CP010337.1_3736416_3737766_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_CP010337.1_3737777_3738917_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_CP010337.1_3738913_3739645_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|763aa|up_1|NZ_CP010337.1_3739653_3741942_-	pfam00823, PPE, PPE family	NA|339aa|up_0|NZ_CP010337.1_3741990_3743007_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|86aa|down_0|NZ_CP010337.1_3748272_3748530_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|1735aa|down_1|NZ_CP010337.1_3748785_3753990_-	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|421aa|down_2|NZ_CP010337.1_3755671_3756933_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|149aa|down_3|NZ_CP010337.1_3760244_3760691_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_4|NZ_CP010337.1_3760727_3761468_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_5|NZ_CP010337.1_3761762_3762050_-	NA	NA|3716aa|down_6|NZ_CP010337.1_3762386_3773534_-	pfam00823, PPE, PPE family	NA|265aa|down_7|NZ_CP010337.1_3773777_3774572_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_8|NZ_CP010337.1_3774653_3775025_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_9|NZ_CP010337.1_3774922_3775141_-	pfam01565, FAD_binding_4, FAD binding domain
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	13	3853129-3853218	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|77aa|up_7|NZ_CP010337.1_3846523_3846754_+,NA|121aa|up_6|NZ_CP010337.1_3846857_3847220_-,NA|73aa|up_2|NZ_CP010337.1_3851194_3851413_-,NA|121aa|down_0|NZ_CP010337.1_3854202_3854565_-,NA|52aa|down_2|NZ_CP010337.1_3856406_3856562_-,NA|52aa|down_3|NZ_CP010337.1_3856586_3856742_-,NA|238aa|down_6|NZ_CP010337.1_3860777_3861491_-	NA|169aa|up_9|NZ_CP010337.1_3844834_3845341_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|409aa|up_8|NZ_CP010337.1_3845337_3846564_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_7|NZ_CP010337.1_3846523_3846754_+	NA	NA|121aa|up_6|NZ_CP010337.1_3846857_3847220_-	NA	NA|177aa|up_5|NZ_CP010337.1_3847382_3847913_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|177aa|up_4|NZ_CP010337.1_3848179_3848710_+	pfam00823, PPE, PPE family	NA|725aa|up_3|NZ_CP010337.1_3849027_3851202_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|73aa|up_2|NZ_CP010337.1_3851194_3851413_-	NA	NA|100aa|up_1|NZ_CP010337.1_3851907_3852207_+	pfam00934, PE, PE family	NA|181aa|up_0|NZ_CP010337.1_3852292_3852835_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_CP010337.1_3854202_3854565_-	NA	NA|179aa|down_1|NZ_CP010337.1_3854727_3855264_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_CP010337.1_3856406_3856562_-	NA	NA|52aa|down_3|NZ_CP010337.1_3856586_3856742_-	NA	NA|461aa|down_4|NZ_CP010337.1_3857934_3859317_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|474aa|down_5|NZ_CP010337.1_3859354_3860776_-	pfam01256, Carb_kinase, Carbohydrate kinase	NA|238aa|down_6|NZ_CP010337.1_3860777_3861491_-	NA	NA|285aa|down_7|NZ_CP010337.1_3861501_3862356_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_8|NZ_CP010337.1_3862577_3864452_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_9|NZ_CP010337.1_3864473_3864950_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	14	3938872-3939864	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CNNCGGCGGCACCGNCGGCACCGGCGGNNNNGGCGGCA	38	1	1	3938910-3939003	NZ_CP010337.1_3938559-3938652	NA	11	11	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP010337.1_3943356_3944196_+	NA|452aa|up_9|NZ_CP010337.1_3920730_3922086_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|358aa|up_8|NZ_CP010337.1_3922082_3923156_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|351aa|up_7|NZ_CP010337.1_3923145_3924198_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|401aa|up_6|NZ_CP010337.1_3924197_3925400_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|281aa|up_5|NZ_CP010337.1_3925419_3926262_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_4|NZ_CP010337.1_3926296_3927061_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_3|NZ_CP010337.1_3927286_3928240_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_2|NZ_CP010337.1_3928264_3928456_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_1|NZ_CP010337.1_3928670_3929873_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|503aa|up_0|NZ_CP010337.1_3931088_3932597_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP010337.1_3940749_3942396_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP010337.1_3942469_3943261_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP010337.1_3943356_3944196_+	NA	NA|399aa|down_3|NZ_CP010337.1_3944250_3945447_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP010337.1_3945475_3946186_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP010337.1_3946250_3947294_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP010337.1_3947446_3948358_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP010337.1_3948373_3949438_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP010337.1_3949454_3950639_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP010337.1_3950680_3951712_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_001544955.1_ASM154495v1	NZ_CP010337	Mycobacterium tuberculosis strain 22115 chromosome, complete genome	15	4100816-4100904	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_6|NZ_CP010337.1_4091402_4092173_-,NA|233aa|up_0|NZ_CP010337.1_4099920_4100619_-,NA|126aa|down_6|NZ_CP010337.1_4106139_4106517_+	NA|388aa|up_9|NZ_CP010337.1_4087073_4088237_-	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase	NA|351aa|up_8|NZ_CP010337.1_4088233_4089286_-	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein	NA|288aa|up_7|NZ_CP010337.1_4089784_4090648_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_6|NZ_CP010337.1_4091402_4092173_-	NA	NA|549aa|up_5|NZ_CP010337.1_4092169_4093816_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_4|NZ_CP010337.1_4093812_4094676_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_3|NZ_CP010337.1_4094668_4095595_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_2|NZ_CP010337.1_4095596_4097222_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|652aa|up_1|NZ_CP010337.1_4097929_4099885_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP010337.1_4099920_4100619_-	NA	NA|173aa|down_0|NZ_CP010337.1_4100964_4101483_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP010337.1_4101483_4102467_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP010337.1_4102459_4103653_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP010337.1_4103658_4104480_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP010337.1_4104611_4105295_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP010337.1_4105294_4106032_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP010337.1_4106139_4106517_+	NA	NA|225aa|down_7|NZ_CP010337.1_4106615_4107290_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP010337.1_4107395_4108190_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP010337.1_4108196_4108652_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
