assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	1	333590-333702	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTCCCGTTGGCGCCGTTGCCGAACAGC	27	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|86aa|up_9|NZ_CP007027.1_322763_323021_-	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|398aa|up_8|NZ_CP007027.1_323337_324531_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_7|NZ_CP007027.1_324566_326249_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_6|NZ_CP007027.1_326265_328461_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_5|NZ_CP007027.1_328574_329708_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_4|NZ_CP007027.1_329704_330325_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_3|NZ_CP007027.1_330421_331003_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_2|NZ_CP007027.1_330932_331658_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_1|NZ_CP007027.1_331747_332668_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_0|NZ_CP007027.1_332707_333136_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|838aa|down_0|NZ_CP007027.1_336559_339073_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP007027.1_339363_340974_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP007027.1_340997_341906_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|614aa|down_3|NZ_CP007027.1_342183_344025_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP007027.1_344021_345638_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP007027.1_345634_349627_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP007027.1_349623_349932_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP007027.1_349934_351476_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP007027.1_351524_351818_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP007027.1_351847_352138_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	2	334569-334722	2	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTCCCGTTGGCGCCGTTGCCGAACAGC	27	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|86aa|up_9|NZ_CP007027.1_322763_323021_-	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|398aa|up_8|NZ_CP007027.1_323337_324531_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_7|NZ_CP007027.1_324566_326249_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_6|NZ_CP007027.1_326265_328461_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_5|NZ_CP007027.1_328574_329708_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_4|NZ_CP007027.1_329704_330325_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_3|NZ_CP007027.1_330421_331003_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_2|NZ_CP007027.1_330932_331658_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_1|NZ_CP007027.1_331747_332668_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_0|NZ_CP007027.1_332707_333136_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|838aa|down_0|NZ_CP007027.1_336559_339073_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP007027.1_339363_340974_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP007027.1_340997_341906_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|614aa|down_3|NZ_CP007027.1_342183_344025_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP007027.1_344021_345638_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP007027.1_345634_349627_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP007027.1_349623_349932_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP007027.1_349934_351476_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP007027.1_351524_351818_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP007027.1_351847_352138_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	3	334887-334997	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTCCCGTTGGCGCCGTTGCCGAACAGC	27	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|86aa|up_9|NZ_CP007027.1_322763_323021_-	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|398aa|up_8|NZ_CP007027.1_323337_324531_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_7|NZ_CP007027.1_324566_326249_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_6|NZ_CP007027.1_326265_328461_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_5|NZ_CP007027.1_328574_329708_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_4|NZ_CP007027.1_329704_330325_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_3|NZ_CP007027.1_330421_331003_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_2|NZ_CP007027.1_330932_331658_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_1|NZ_CP007027.1_331747_332668_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_0|NZ_CP007027.1_332707_333136_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|838aa|down_0|NZ_CP007027.1_336559_339073_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP007027.1_339363_340974_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP007027.1_340997_341906_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|614aa|down_3|NZ_CP007027.1_342183_344025_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP007027.1_344021_345638_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP007027.1_345634_349627_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP007027.1_349623_349932_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP007027.1_349934_351476_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP007027.1_351524_351818_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP007027.1_351847_352138_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	4	335385-335957	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGCNCCGCCGNNGCCG	21	3	3	335805-335828|335850-335882|335904-335936	NZ_CP007027.1_338586-338609|NZ_CP007027.1_338613-338645|NZ_CP007027.1_338667-338699	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|86aa|up_9|NZ_CP007027.1_322763_323021_-	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|398aa|up_8|NZ_CP007027.1_323337_324531_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_7|NZ_CP007027.1_324566_326249_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_6|NZ_CP007027.1_326265_328461_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_5|NZ_CP007027.1_328574_329708_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_4|NZ_CP007027.1_329704_330325_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_3|NZ_CP007027.1_330421_331003_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_2|NZ_CP007027.1_330932_331658_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_1|NZ_CP007027.1_331747_332668_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_0|NZ_CP007027.1_332707_333136_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|838aa|down_0|NZ_CP007027.1_336559_339073_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP007027.1_339363_340974_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP007027.1_340997_341906_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|614aa|down_3|NZ_CP007027.1_342183_344025_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP007027.1_344021_345638_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP007027.1_345634_349627_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP007027.1_349623_349932_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP007027.1_349934_351476_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP007027.1_351524_351818_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP007027.1_351847_352138_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	5	366463-367161	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366751-366792|366826-366858	NZ_CP007027.1_374783-374824|NZ_CP007027.1_373598-373630	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP007027.1_363475_363778_+,NA|161aa|down_1|NZ_CP007027.1_376572_377055_-,NA|410aa|down_5|NZ_CP007027.1_379171_380401_+	NA|262aa|up_9|NZ_CP007027.1_358170_358956_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP007027.1_358944_359748_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP007027.1_359757_361155_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP007027.1_361333_363109_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP007027.1_363251_363479_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP007027.1_363475_363778_+	NA	NA|74aa|up_3|NZ_CP007027.1_363825_364047_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP007027.1_364043_364469_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP007027.1_364604_365237_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP007027.1_365233_366142_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP007027.1_375913_376585_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP007027.1_376572_377055_-	NA	NA|239aa|down_2|NZ_CP007027.1_377112_377829_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP007027.1_377930_378587_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP007027.1_378656_379148_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP007027.1_379171_380401_+	NA	NA|621aa|down_6|NZ_CP007027.1_380555_382418_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP007027.1_382489_382876_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|212aa|down_8|NZ_CP007027.1_382878_383514_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP007027.1_383601_384486_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	6	692028-692104	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP007027.1_677712_677928_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP007027.1_677924_678332_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP007027.1_678391_679078_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP007027.1_679231_681865_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP007027.1_681887_684275_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP007027.1_684412_685135_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP007027.1_685131_685929_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP007027.1_685930_686818_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP007027.1_686823_688038_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP007027.1_689061_690507_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP007027.1_693239_694790_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP007027.1_694841_695234_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP007027.1_695230_695488_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP007027.1_695670_696906_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP007027.1_697156_697570_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP007027.1_697566_697803_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP007027.1_697906_698413_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|177aa|down_7|NZ_CP007027.1_698526_699057_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP007027.1_699040_699802_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP007027.1_699858_700170_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	7	926623-927570	2	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGNGCCGGCGGNNCCGGCGG	21	1	3	927406-927441|927406-927441|927406-927441	NZ_CP007027.1_675131-675096|NZ_CP007027.1_1213754-1213789|NZ_CP007027.1_2423181-2423146	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP007027.1_931580_932132_-	NA|685aa|up_9|NZ_CP007027.1_914259_916314_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP007027.1_916479_917649_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP007027.1_917736_918753_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP007027.1_918914_919556_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP007027.1_919636_920692_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP007027.1_920743_921136_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP007027.1_921193_921616_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|302aa|up_2|NZ_CP007027.1_921972_922878_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_1|NZ_CP007027.1_922896_923712_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|138aa|up_0|NZ_CP007027.1_924953_925367_+	pfam00934, PE, PE family	NA|883aa|down_0|NZ_CP007027.1_927839_930488_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP007027.1_930955_931600_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP007027.1_931580_932132_-	NA	NA|218aa|down_3|NZ_CP007027.1_932281_932935_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP007027.1_933005_934034_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP007027.1_934722_935493_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP007027.1_935579_936392_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP007027.1_936459_937320_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|431aa|down_8|NZ_CP007027.1_938114_939407_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|335aa|down_9|NZ_CP007027.1_939390_940395_+	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	8	1191321-1191429	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP007027.1_1180688_1182320_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP007027.1_1182395_1183460_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP007027.1_1183512_1183986_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP007027.1_1184019_1184883_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP007027.1_1184887_1185745_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP007027.1_1185745_1186828_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP007027.1_1186908_1187328_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP007027.1_1187439_1188006_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP007027.1_1188002_1188398_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP007027.1_1188425_1190429_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP007027.1_1192514_1194278_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP007027.1_1194274_1195048_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP007027.1_1195059_1196097_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP007027.1_1196283_1197120_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP007027.1_1197235_1198087_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP007027.1_1198160_1199378_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP007027.1_1199430_1200375_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|298aa|down_7|NZ_CP007027.1_1200771_1201665_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP007027.1_1201721_1203116_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP007027.1_1203317_1204040_+	pfam06271, RDD, RDD family
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	9	1211955-1212811	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	70	1212338-1212359|1212383-1212398|1212521-1212542|1212521-1212542|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656|1212638-1212656	NZ_CP007027.1_2959946-2959925|NZ_CP007027.1_2088007-2087992|NZ_CP007027.1_837437-837458|NZ_CP007027.1_1217649-1217670|NZ_CP007027.1_674795-674777|NZ_CP007027.1_1213481-1213499|NZ_CP007027.1_1217622-1217640|NZ_CP007027.1_1217694-1217712|NZ_CP007027.1_1630703-1630685|NZ_CP007027.1_1633529-1633511|NZ_CP007027.1_1990211-1990193|NZ_CP007027.1_2060935-2060917|NZ_CP007027.1_2061382-2061364|NZ_CP007027.1_2061481-2061463|NZ_CP007027.1_2801494-2801476|NZ_CP007027.1_2805022-2805004|NZ_CP007027.1_150181-150199|NZ_CP007027.1_333782-333764|NZ_CP007027.1_335201-335183|NZ_CP007027.1_338003-337985|NZ_CP007027.1_338132-338114|NZ_CP007027.1_338399-338381|NZ_CP007027.1_338428-338446|NZ_CP007027.1_338522-338504|NZ_CP007027.1_363053-363035|NZ_CP007027.1_443428-443410|NZ_CP007027.1_546772-546754|NZ_CP007027.1_623986-624004|NZ_CP007027.1_624208-624226|NZ_CP007027.1_673961-673943|NZ_CP007027.1_840220-840238|NZ_CP007027.1_1090985-1091003|NZ_CP007027.1_1091633-1091651|NZ_CP007027.1_1095691-1095673|NZ_CP007027.1_1213010-1213028|NZ_CP007027.1_1213400-1213418|NZ_CP007027.1_1218042-1218060|NZ_CP007027.1_1489215-1489197|NZ_CP007027.1_1618667-1618649|NZ_CP007027.1_1619120-1619102|NZ_CP007027.1_1636042-1636024|NZ_CP007027.1_1636051-1636033|NZ_CP007027.1_1864329-1864311|NZ_CP007027.1_1864857-1864839|NZ_CP007027.1_1989485-1989467|NZ_CP007027.1_2000847-2000865|NZ_CP007027.1_2088205-2088187|NZ_CP007027.1_2302900-2302882|NZ_CP007027.1_2356352-2356334|NZ_CP007027.1_2419007-2419025|NZ_CP007027.1_2423094-2423076|NZ_CP007027.1_2568587-2568569|NZ_CP007027.1_2692885-2692903|NZ_CP007027.1_2794809-2794791|NZ_CP007027.1_2795391-2795373|NZ_CP007027.1_3053982-3054000|NZ_CP007027.1_3054081-3054099|NZ_CP007027.1_3704896-3704914|NZ_CP007027.1_3736873-3736855|NZ_CP007027.1_3737497-3737479|NZ_CP007027.1_3737740-3737722|NZ_CP007027.1_3737873-3737855|NZ_CP007027.1_3801736-3801754|NZ_CP007027.1_3801919-3801937|NZ_CP007027.1_3802087-3802105|NZ_CP007027.1_3929900-3929918|NZ_CP007027.1_3931630-3931648|NZ_CP007027.1_3940137-3940155|NZ_CP007027.1_4031115-4031097|NZ_CP007027.1_4093641-4093659	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP007027.1_1207387_1207654_+,NA|61aa|down_2|NZ_CP007027.1_1215229_1215412_+,NA|35aa|down_3|NZ_CP007027.1_1215521_1215626_+	NA|465aa|up_9|NZ_CP007027.1_1201721_1203116_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP007027.1_1203317_1204040_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP007027.1_1204071_1205238_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP007027.1_1205308_1205803_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP007027.1_1205988_1206423_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP007027.1_1206524_1207391_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP007027.1_1207387_1207654_+	NA	NA|674aa|up_2|NZ_CP007027.1_1207640_1209662_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP007027.1_1209760_1210489_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP007027.1_1210599_1211388_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP007027.1_1214044_1214365_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|56aa|down_1|NZ_CP007027.1_1215050_1215218_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_2|NZ_CP007027.1_1215229_1215412_+	NA	NA|35aa|down_3|NZ_CP007027.1_1215521_1215626_+	NA	NA|152aa|down_4|NZ_CP007027.1_1215603_1216059_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_5|NZ_CP007027.1_1216473_1219035_+	pfam00934, PE, PE family	NA|313aa|down_6|NZ_CP007027.1_1219252_1220191_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_7|NZ_CP007027.1_1220578_1221859_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_8|NZ_CP007027.1_1221963_1222791_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|434aa|down_9|NZ_CP007027.1_1223001_1224303_+	COG1875, COG1875, NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	10	1572190-1573262	8	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP007027.1_1563953_1564271_+,NA	NA|103aa|up_9|NZ_CP007027.1_1561468_1561777_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP007027.1_1561773_1563393_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP007027.1_1563953_1564271_+	NA	NA|209aa|up_6|NZ_CP007027.1_1564405_1565032_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP007027.1_1565097_1565430_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP007027.1_1565445_1566702_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP007027.1_1566829_1568041_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP007027.1_1568113_1569592_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP007027.1_1569588_1570974_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP007027.1_1571051_1572086_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP007027.1_1574116_1574518_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP007027.1_1574514_1574772_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP007027.1_1574854_1575814_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP007027.1_1575838_1576801_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|246aa|down_4|NZ_CP007027.1_1576799_1577537_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP007027.1_1577617_1579585_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP007027.1_1579602_1580427_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP007027.1_1580595_1581078_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP007027.1_1581149_1581974_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP007027.1_1582170_1583109_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	11	1636906-1637094	3	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGGCCCCGCCGGC	18	1	2	1637005-1637022|1637005-1637022	NZ_CP007027.1_2801401-2801418|NZ_CP007027.1_3766120-3766137	NA	4	4	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP007027.1_1623128_1623242_-,NA|137aa|up_7|NZ_CP007027.1_1623291_1623702_-,NA|288aa|down_2|NZ_CP007027.1_1640684_1641548_+	NA|155aa|up_9|NZ_CP007027.1_1622211_1622676_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP007027.1_1623128_1623242_-	NA	NA|137aa|up_7|NZ_CP007027.1_1623291_1623702_-	NA	NA|248aa|up_6|NZ_CP007027.1_1623718_1624462_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP007027.1_1624458_1625370_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP007027.1_1625422_1626967_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP007027.1_1626963_1628085_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP007027.1_1628101_1630204_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP007027.1_1630642_1634632_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP007027.1_1635033_1635960_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP007027.1_1638385_1639651_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP007027.1_1639678_1640665_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP007027.1_1640684_1641548_+	NA	NA|311aa|down_3|NZ_CP007027.1_1641497_1642430_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP007027.1_1642541_1643327_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP007027.1_1643323_1644265_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP007027.1_1644367_1646143_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP007027.1_1646190_1646997_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP007027.1_1646993_1649534_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP007027.1_1649530_1650724_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	12	2087677-2087931	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2087758-2087775|2087758-2087775|2087848-2087865	NZ_CP007027.1_401079-401062|NZ_CP007027.1_607441-607424|NZ_CP007027.1_3449597-3449580	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP007027.1_2087036_2087300_-,NA	NA|165aa|up_9|NZ_CP007027.1_2073330_2073825_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|211aa|up_8|NZ_CP007027.1_2074273_2074906_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP007027.1_2075264_2078090_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP007027.1_2078316_2079177_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP007027.1_2079217_2080084_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP007027.1_2080088_2081975_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP007027.1_2081990_2084024_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP007027.1_2084143_2086369_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP007027.1_2086644_2087040_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP007027.1_2087036_2087300_-	NA	NA|346aa|down_0|NZ_CP007027.1_2089068_2090106_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP007027.1_2090105_2091473_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|480aa|down_2|NZ_CP007027.1_2091646_2093086_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|486aa|down_3|NZ_CP007027.1_2093118_2094576_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP007027.1_2094605_2095556_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP007027.1_2095570_2095987_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP007027.1_2096264_2096687_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP007027.1_2096735_2097038_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP007027.1_2097034_2097349_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP007027.1_2097348_2099082_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	13	2168202-2168421	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP007027.1_2159308_2159716_-,NA|127aa|down_5|NZ_CP007027.1_2175937_2176318_-	NA|741aa|up_9|NZ_CP007027.1_2153276_2155499_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP007027.1_2155536_2155980_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP007027.1_2156093_2156687_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP007027.1_2156769_2157375_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP007027.1_2157474_2158479_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP007027.1_2158578_2159331_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP007027.1_2159308_2159716_-	NA	NA|368aa|up_2|NZ_CP007027.1_2159850_2160954_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP007027.1_2160953_2162150_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP007027.1_2162319_2166699_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP007027.1_2170448_2170913_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP007027.1_2171010_2171874_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP007027.1_2171911_2173183_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP007027.1_2173454_2174570_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP007027.1_2174560_2175901_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP007027.1_2175937_2176318_-	NA	NA|621aa|down_6|NZ_CP007027.1_2176474_2178337_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP007027.1_2178344_2178824_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP007027.1_2179060_2179834_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP007027.1_2179837_2180605_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	14	3118573-3119927	1,10,5	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-A,Type III-C,Type III-D,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-A,TypeIII-C,TypeIII-D,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_7|NZ_CP007027.1_3111852_3112107_-,NA|135aa|up_6|NZ_CP007027.1_3112254_3112659_+,NA|64aa|up_5|NZ_CP007027.1_3112655_3112847_+,NA|86aa|up_4|NZ_CP007027.1_3114433_3114691_+,NA|104aa|up_3|NZ_CP007027.1_3114795_3115107_+,NA|203aa|up_2|NZ_CP007027.1_3115526_3116135_+,NA	NA|348aa|up_9|NZ_CP007027.1_3110167_3111211_-	COG5586, COG5586, Uncharacterized conserved protein [Function unknown]	NA|92aa|up_8|NZ_CP007027.1_3111401_3111677_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_7|NZ_CP007027.1_3111852_3112107_-	NA	NA|135aa|up_6|NZ_CP007027.1_3112254_3112659_+	NA	NA|64aa|up_5|NZ_CP007027.1_3112655_3112847_+	NA	NA|86aa|up_4|NZ_CP007027.1_3114433_3114691_+	NA	NA|104aa|up_3|NZ_CP007027.1_3114795_3115107_+	NA	NA|203aa|up_2|NZ_CP007027.1_3115526_3116135_+	NA	NA|470aa|up_1|NZ_CP007027.1_3116205_3117615_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP007027.1_3117611_3118424_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP007027.1_3119953_3121215_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP007027.1_3123012_3123354_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP007027.1_3123354_3124371_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|416aa|down_3|NZ_CP007027.1_3124383_3125631_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP007027.1_3125627_3126755_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP007027.1_3126751_3127660_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP007027.1_3127640_3128351_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP007027.1_3128360_3128735_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_8|NZ_CP007027.1_3128731_3131161_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|263aa|down_9|NZ_CP007027.1_3131157_3131946_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	15	3121250-3122964	11,6,2,3	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-A,Type III-C,Type III-D,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A:II-B,III-A	23,23,20,20	23	TypeIII-A,TypeIII-C,TypeIII-D,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP007027.1_3111852_3112107_-,NA|135aa|up_7|NZ_CP007027.1_3112254_3112659_+,NA|64aa|up_6|NZ_CP007027.1_3112655_3112847_+,NA|86aa|up_5|NZ_CP007027.1_3114433_3114691_+,NA|104aa|up_4|NZ_CP007027.1_3114795_3115107_+,NA|203aa|up_3|NZ_CP007027.1_3115526_3116135_+,NA	NA|92aa|up_9|NZ_CP007027.1_3111401_3111677_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP007027.1_3111852_3112107_-	NA	NA|135aa|up_7|NZ_CP007027.1_3112254_3112659_+	NA	NA|64aa|up_6|NZ_CP007027.1_3112655_3112847_+	NA	NA|86aa|up_5|NZ_CP007027.1_3114433_3114691_+	NA	NA|104aa|up_4|NZ_CP007027.1_3114795_3115107_+	NA	NA|203aa|up_3|NZ_CP007027.1_3115526_3116135_+	NA	NA|470aa|up_2|NZ_CP007027.1_3116205_3117615_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP007027.1_3117611_3118424_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP007027.1_3119953_3121215_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP007027.1_3123012_3123354_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP007027.1_3123354_3124371_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|416aa|down_2|NZ_CP007027.1_3124383_3125631_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP007027.1_3125627_3126755_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP007027.1_3126751_3127660_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP007027.1_3127640_3128351_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP007027.1_3128360_3128735_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_7|NZ_CP007027.1_3128731_3131161_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|263aa|down_8|NZ_CP007027.1_3131157_3131946_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP007027.1_3132279_3132825_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	16	3740067-3740608	7	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP007027.1_3754709_3754997_-	NA|147aa|up_9|NZ_CP007027.1_3720638_3721079_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_8|NZ_CP007027.1_3721112_3721982_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_7|NZ_CP007027.1_3722002_3723013_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|215aa|up_6|NZ_CP007027.1_3723285_3723930_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_5|NZ_CP007027.1_3723996_3725226_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_4|NZ_CP007027.1_3725508_3726858_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_CP007027.1_3726869_3728009_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_CP007027.1_3728005_3728737_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_1|NZ_CP007027.1_3728745_3736317_-	pfam00823, PPE, PPE family	NA|339aa|up_0|NZ_CP007027.1_3736365_3737382_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|86aa|down_0|NZ_CP007027.1_3742579_3742837_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP007027.1_3743092_3752566_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP007027.1_3753191_3753638_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP007027.1_3753674_3754415_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP007027.1_3754709_3754997_-	NA	NA|3717aa|down_5|NZ_CP007027.1_3755333_3766484_-	pfam00823, PPE, PPE family	NA|130aa|down_6|NZ_CP007027.1_3768492_3768882_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|98aa|down_7|NZ_CP007027.1_3768895_3769189_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|282aa|down_8|NZ_CP007027.1_3769185_3770031_-	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional	NA|92aa|down_9|NZ_CP007027.1_3770154_3770430_+	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	17	3761865-3761991	4	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTTGCCGATGCCGGTGTTGAAA	22	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|96aa|up_0|NZ_CP007027.1_3754709_3754997_-,NA	NA|380aa|up_9|NZ_CP007027.1_3726869_3728009_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_8|NZ_CP007027.1_3728005_3728737_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_7|NZ_CP007027.1_3728745_3736317_-	pfam00823, PPE, PPE family	NA|339aa|up_6|NZ_CP007027.1_3736365_3737382_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|1539aa|up_5|NZ_CP007027.1_3737539_3742156_-	pfam00934, PE, PE family	NA|86aa|up_4|NZ_CP007027.1_3742579_3742837_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|up_3|NZ_CP007027.1_3743092_3752566_-	pfam00823, PPE, PPE family	NA|149aa|up_2|NZ_CP007027.1_3753191_3753638_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|up_1|NZ_CP007027.1_3753674_3754415_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|up_0|NZ_CP007027.1_3754709_3754997_-	NA	NA|130aa|down_0|NZ_CP007027.1_3768492_3768882_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|98aa|down_1|NZ_CP007027.1_3768895_3769189_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|282aa|down_2|NZ_CP007027.1_3769185_3770031_-	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional	NA|92aa|down_3|NZ_CP007027.1_3770154_3770430_+	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|86aa|down_4|NZ_CP007027.1_3770426_3770684_+	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system	NA|397aa|down_5|NZ_CP007027.1_3770725_3771916_+	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain	NA|123aa|down_6|NZ_CP007027.1_3772032_3772401_+	pfam00498, FHA, FHA domain	NA|184aa|down_7|NZ_CP007027.1_3772397_3772949_-	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]	NA|194aa|down_8|NZ_CP007027.1_3772955_3773537_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|123aa|down_9|NZ_CP007027.1_3773517_3773886_-	pfam05331, DUF742, Protein of unknown function (DUF742)
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	18	3947745-3949496	8	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCNNCGGCGGNNNCGGCGG	36	2	9	3948336-3948371|3948336-3948371|3948336-3948371|3948336-3948371|3948336-3948371|3949227-3949253|3949227-3949253|3949227-3949253|3949227-3949253	NZ_CP007027.1_3946452-3946487|NZ_CP007027.1_3946794-3946829|NZ_CP007027.1_3947385-3947420|NZ_CP007027.1_3947736-3947771|NZ_CP007027.1_3932185-3932220|NZ_CP007027.1_361993-362019|NZ_CP007027.1_3940638-3940664|NZ_CP007027.1_3940974-3941000|NZ_CP007027.1_3941320-3941346	NA	21	21	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|134aa|up_1|NZ_CP007027.1_3942478_3942880_-,NA|384aa|up_0|NZ_CP007027.1_3943192_3944344_+,NA|280aa|down_2|NZ_CP007027.1_3952811_3953651_+	NA|374aa|up_9|NZ_CP007027.1_3923078_3924200_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_8|NZ_CP007027.1_3924270_3925779_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1382aa|up_7|NZ_CP007027.1_3925949_3930095_+	pfam00934, PE, PE family	NA|1902aa|up_6|NZ_CP007027.1_3930385_3936091_+	pfam00934, PE, PE family	NA|516aa|up_5|NZ_CP007027.1_3936257_3937805_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_4|NZ_CP007027.1_3937801_3938638_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|715aa|up_3|NZ_CP007027.1_3938997_3941142_+	pfam00934, PE, PE family	NA|446aa|up_2|NZ_CP007027.1_3941101_3942439_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|134aa|up_1|NZ_CP007027.1_3942478_3942880_-	NA	NA|384aa|up_0|NZ_CP007027.1_3943192_3944344_+	NA	NA|549aa|down_0|NZ_CP007027.1_3950204_3951851_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP007027.1_3951924_3952716_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP007027.1_3952811_3953651_+	NA	NA|399aa|down_3|NZ_CP007027.1_3953705_3954902_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP007027.1_3954930_3955641_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|344aa|down_5|NZ_CP007027.1_3955705_3956737_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|335aa|down_6|NZ_CP007027.1_3956808_3957813_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP007027.1_3957828_3958893_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP007027.1_3958909_3960094_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP007027.1_3960135_3961167_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_000827085.1_ASM82708v1	NZ_CP007027	Mycobacterium tuberculosis H37RvSiena chromosome, complete genome	19	4110058-4110146	12	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_6|NZ_CP007027.1_4100644_4101415_-,NA|233aa|up_0|NZ_CP007027.1_4109162_4109861_-,NA|126aa|down_6|NZ_CP007027.1_4115381_4115759_+	NA|388aa|up_9|NZ_CP007027.1_4096315_4097479_-	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase	NA|351aa|up_8|NZ_CP007027.1_4097475_4098528_-	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein	NA|288aa|up_7|NZ_CP007027.1_4099026_4099890_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_6|NZ_CP007027.1_4100644_4101415_-	NA	NA|549aa|up_5|NZ_CP007027.1_4101411_4103058_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_4|NZ_CP007027.1_4103054_4103918_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_3|NZ_CP007027.1_4103910_4104837_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_2|NZ_CP007027.1_4104838_4106464_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|652aa|up_1|NZ_CP007027.1_4107171_4109127_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP007027.1_4109162_4109861_-	NA	NA|173aa|down_0|NZ_CP007027.1_4110206_4110725_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP007027.1_4110725_4111709_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP007027.1_4111701_4112895_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP007027.1_4112900_4113722_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|216aa|down_4|NZ_CP007027.1_4113853_4114501_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP007027.1_4114536_4115274_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP007027.1_4115381_4115759_+	NA	NA|225aa|down_7|NZ_CP007027.1_4115857_4116532_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP007027.1_4116637_4117432_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP007027.1_4117438_4117894_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
