assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	1	338040-338262	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NC_021194.1_333095_333278_-,NA|87aa|down_0|NC_021194.1_339042_339303_+	NA|331aa|up_9|NC_021194.1_316462_317455_-	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]	NA|170aa|up_8|NC_021194.1_322705_323215_-	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|561aa|up_7|NC_021194.1_324509_326192_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|378aa|up_6|NC_021194.1_328510_329644_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NC_021194.1_329640_330261_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NC_021194.1_330357_330939_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NC_021194.1_330868_331594_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NC_021194.1_331683_332604_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NC_021194.1_332643_333072_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NC_021194.1_333095_333278_-	NA	NA|87aa|down_0|NC_021194.1_339042_339303_+	NA	NA|537aa|down_1|NC_021194.1_339299_340910_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NC_021194.1_340933_341842_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|1331aa|down_3|NC_021194.1_345566_349559_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_4|NC_021194.1_349555_349864_+	pfam00934, PE, PE family	NA|514aa|down_5|NC_021194.1_349866_351408_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_6|NC_021194.1_351456_351750_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_7|NC_021194.1_351779_352070_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_8|NC_021194.1_352080_352968_+	pfam14011, ESX-1_EspG, EspG family	NA|473aa|down_9|NC_021194.1_353014_354433_+	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	2	631171-631308	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGACCACGCCGGTG	18	2	3	631189-631206|631189-631206|631273-631290	NC_021194.1_22458-22475|NC_021194.1_1410487-1410504|NC_021194.1_971708-971725	NA	3	3	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|54aa|up_7|NC_021194.1_622010_622172_-,NA|61aa|up_5|NC_021194.1_622507_622690_+,NA|478aa|up_0|NC_021194.1_628186_629620_-,NA|450aa|down_2|NC_021194.1_632943_634293_-,NA|93aa|down_5|NC_021194.1_635823_636102_-	NA|325aa|up_9|NC_021194.1_619780_620755_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NC_021194.1_620796_622014_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NC_021194.1_622010_622172_-	NA	NA|106aa|up_6|NC_021194.1_622218_622536_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|61aa|up_5|NC_021194.1_622507_622690_+	NA	NA|595aa|up_4|NC_021194.1_622682_624467_+	pfam00934, PE, PE family	NA|336aa|up_3|NC_021194.1_624362_625370_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_2|NC_021194.1_625451_626330_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|347aa|up_1|NC_021194.1_627136_628177_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NC_021194.1_628186_629620_-	NA	NA|211aa|down_0|NC_021194.1_631631_632264_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NC_021194.1_632260_632923_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NC_021194.1_632943_634293_-	NA	NA|381aa|down_3|NC_021194.1_634304_635447_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NC_021194.1_635461_635764_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NC_021194.1_635823_636102_-	NA	NA|418aa|down_6|NC_021194.1_636098_637352_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NC_021194.1_637471_637858_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NC_021194.1_637920_638805_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NC_021194.1_638900_639803_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	3	691907-691983	1	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|136aa|up_9|NC_021194.1_677805_678213_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NC_021194.1_678272_678959_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NC_021194.1_679112_681746_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NC_021194.1_681768_684156_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NC_021194.1_684293_685016_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NC_021194.1_685012_685810_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|295aa|up_3|NC_021194.1_685811_686696_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NC_021194.1_686701_687916_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|344aa|up_1|NC_021194.1_687912_688944_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|482aa|up_0|NC_021194.1_688940_690386_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NC_021194.1_693118_694669_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NC_021194.1_694720_695113_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NC_021194.1_695109_695367_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NC_021194.1_695549_696785_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NC_021194.1_697035_697449_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NC_021194.1_697445_697682_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NC_021194.1_697785_698292_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NC_021194.1_698405_698876_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NC_021194.1_698919_699681_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NC_021194.1_699737_700049_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	4	925098-926045	2	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGNGCCGGCGGNNCCGGCGG	21	1	3	925881-925916|925881-925916|925881-925916	NC_021194.1_675012-674977|NC_021194.1_1212190-1212225|NC_021194.1_2416593-2416558	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|60aa|down_0|NC_021194.1_926106_926286_+,NA|184aa|down_3|NC_021194.1_930055_930607_-,NA|63aa|down_5|NC_021194.1_932769_932958_-,NA|88aa|down_9|NC_021194.1_935881_936145_+	NA|259aa|up_9|NC_021194.1_911202_911979_+	PRK14241, PRK14241, phosphate transporter ATP-binding protein; Provisional	NA|214aa|up_8|NC_021194.1_912034_912676_-	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU	NA|685aa|up_7|NC_021194.1_912733_914788_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_6|NC_021194.1_914953_916123_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_5|NC_021194.1_916210_917227_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_4|NC_021194.1_917388_918030_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_3|NC_021194.1_918110_919166_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_2|NC_021194.1_919217_919610_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|302aa|up_1|NC_021194.1_920447_921353_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NC_021194.1_921371_922187_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|60aa|down_0|NC_021194.1_926106_926286_+	NA	NA|883aa|down_1|NC_021194.1_926314_928963_-	pfam00934, PE, PE family	NA|215aa|down_2|NC_021194.1_929430_930075_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_3|NC_021194.1_930055_930607_-	NA	NA|241aa|down_4|NC_021194.1_930687_931410_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|63aa|down_5|NC_021194.1_932769_932958_-	NA	NA|257aa|down_6|NC_021194.1_933196_933967_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_7|NC_021194.1_934053_934866_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_8|NC_021194.1_934933_935794_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|88aa|down_9|NC_021194.1_935881_936145_+	NA
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	5	963055-963306	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGT	63	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|67aa|up_3|NC_021194.1_961153_961354_+,NA|64aa|down_5|NC_021194.1_968792_968984_-	NA|153aa|up_9|NC_021194.1_951246_951705_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|158aa|up_8|NC_021194.1_951732_952206_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|398aa|up_7|NC_021194.1_952202_953396_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|721aa|up_6|NC_021194.1_954766_956929_+	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB	NA|543aa|up_5|NC_021194.1_956996_958625_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|757aa|up_4|NC_021194.1_958815_961086_-	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|67aa|up_3|NC_021194.1_961153_961354_+	NA	NA|168aa|up_2|NC_021194.1_961363_961867_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|161aa|up_1|NC_021194.1_961863_962346_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|142aa|up_0|NC_021194.1_962342_962768_+	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism]	NA|93aa|down_0|NC_021194.1_964453_964732_-	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins	NA|360aa|down_1|NC_021194.1_964735_965815_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|130aa|down_2|NC_021194.1_965811_966201_-	PRK11770, PRK11770, YccF domain-containing protein	NA|136aa|down_3|NC_021194.1_966365_966773_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|607aa|down_4|NC_021194.1_966891_968712_-	pfam00934, PE, PE family	NA|64aa|down_5|NC_021194.1_968792_968984_-	NA	NA|651aa|down_6|NC_021194.1_968972_970925_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|387aa|down_7|NC_021194.1_971013_972174_-	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|163aa|down_8|NC_021194.1_972273_972762_-	pfam10969, DUF2771, Protein of unknown function (DUF2771)	NA|549aa|down_9|NC_021194.1_972758_974405_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	6	1189757-1189865	2	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|394aa|up_9|NC_021194.1_1177838_1179020_+	COG3391, COG3391, Uncharacterized conserved protein [Function unknown]	NA|544aa|up_8|NC_021194.1_1179126_1180758_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_7|NC_021194.1_1180833_1181898_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_6|NC_021194.1_1181950_1182424_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_5|NC_021194.1_1182457_1183321_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_4|NC_021194.1_1183325_1184183_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|140aa|up_3|NC_021194.1_1185344_1185764_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NC_021194.1_1185875_1186442_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NC_021194.1_1186438_1186834_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NC_021194.1_1186861_1188865_-	pfam00934, PE, PE family	NA|588aa|down_0|NC_021194.1_1190950_1192714_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NC_021194.1_1192710_1193484_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NC_021194.1_1193495_1194533_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NC_021194.1_1194719_1195556_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NC_021194.1_1195671_1196523_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NC_021194.1_1196596_1197814_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NC_021194.1_1197866_1198811_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|298aa|down_7|NC_021194.1_1199207_1200101_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NC_021194.1_1200157_1201552_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NC_021194.1_1201753_1202476_+	pfam06271, RDD, RDD family
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	7	1210391-1211247	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	73	1210774-1210795|1210819-1210834|1210957-1210978|1210957-1210978|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092|1211074-1211092	NC_021194.1_2947837-2947816|NC_021194.1_2082846-2082831|NC_021194.1_837280-837301|NC_021194.1_1216085-1216106|NC_021194.1_674676-674658|NC_021194.1_840342-840360|NC_021194.1_1211917-1211935|NC_021194.1_1216058-1216076|NC_021194.1_1216130-1216148|NC_021194.1_1627719-1627701|NC_021194.1_1630545-1630527|NC_021194.1_1986421-1986403|NC_021194.1_2055774-2055756|NC_021194.1_2056221-2056203|NC_021194.1_2056320-2056302|NC_021194.1_2789410-2789392|NC_021194.1_2792937-2792919|NC_021194.1_150154-150172|NC_021194.1_333718-333700|NC_021194.1_335137-335119|NC_021194.1_335590-335572|NC_021194.1_335641-335623|NC_021194.1_335650-335632|NC_021194.1_337939-337921|NC_021194.1_338335-338317|NC_021194.1_338364-338382|NC_021194.1_338458-338440|NC_021194.1_362982-362964|NC_021194.1_443353-443335|NC_021194.1_546679-546661|NC_021194.1_623873-623891|NC_021194.1_624095-624113|NC_021194.1_673842-673824|NC_021194.1_840063-840081|NC_021194.1_1089429-1089447|NC_021194.1_1090077-1090095|NC_021194.1_1094135-1094117|NC_021194.1_1211446-1211464|NC_021194.1_1211836-1211854|NC_021194.1_1216478-1216496|NC_021194.1_1487599-1487581|NC_021194.1_1615684-1615666|NC_021194.1_1616137-1616119|NC_021194.1_1633058-1633040|NC_021194.1_1633067-1633049|NC_021194.1_1861307-1861289|NC_021194.1_1861835-1861817|NC_021194.1_1985695-1985677|NC_021194.1_1995702-1995720|NC_021194.1_2083044-2083026|NC_021194.1_2297703-2297685|NC_021194.1_2351138-2351120|NC_021194.1_2412419-2412437|NC_021194.1_2416506-2416488|NC_021194.1_2559263-2559245|NC_021194.1_2682172-2682190|NC_021194.1_2782725-2782707|NC_021194.1_2783307-2783289|NC_021194.1_3040512-3040530|NC_021194.1_3040611-3040629|NC_021194.1_3688513-3688531|NC_021194.1_3719132-3719114|NC_021194.1_3719756-3719738|NC_021194.1_3719999-3719981|NC_021194.1_3720132-3720114|NC_021194.1_3782622-3782640|NC_021194.1_3782805-3782823|NC_021194.1_3782973-3782991|NC_021194.1_3909404-3909422|NC_021194.1_3911134-3911152|NC_021194.1_3919641-3919659|NC_021194.1_4010585-4010567|NC_021194.1_4073087-4073105	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NC_021194.1_1205823_1206090_+,NA|90aa|up_0|NC_021194.1_1209840_1210110_-,NA|61aa|down_3|NC_021194.1_1213665_1213848_+,NA|35aa|down_4|NC_021194.1_1213957_1214062_+	NA|465aa|up_9|NC_021194.1_1200157_1201552_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NC_021194.1_1201753_1202476_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NC_021194.1_1202507_1203674_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NC_021194.1_1203744_1204239_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NC_021194.1_1204424_1204859_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NC_021194.1_1204960_1205827_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NC_021194.1_1205823_1206090_+	NA	NA|674aa|up_2|NC_021194.1_1206076_1208098_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NC_021194.1_1208196_1208925_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|90aa|up_0|NC_021194.1_1209840_1210110_-	NA	NA|107aa|down_0|NC_021194.1_1212480_1212801_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NC_021194.1_1212953_1213388_+	pfam00934, PE, PE family	NA|63aa|down_2|NC_021194.1_1213465_1213654_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NC_021194.1_1213665_1213848_+	NA	NA|35aa|down_4|NC_021194.1_1213957_1214062_+	NA	NA|152aa|down_5|NC_021194.1_1214039_1214495_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NC_021194.1_1214909_1217471_+	pfam00934, PE, PE family	NA|313aa|down_7|NC_021194.1_1217688_1218627_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NC_021194.1_1219014_1220295_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NC_021194.1_1220399_1221227_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	8	1569208-1570280	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|74aa|up_8|NC_021194.1_1560508_1560730_-,NA|106aa|up_7|NC_021194.1_1560971_1561289_+,NA	NA|540aa|up_9|NC_021194.1_1558791_1560411_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|74aa|up_8|NC_021194.1_1560508_1560730_-	NA	NA|106aa|up_7|NC_021194.1_1560971_1561289_+	NA	NA|209aa|up_6|NC_021194.1_1561423_1562050_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NC_021194.1_1562115_1562448_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NC_021194.1_1562463_1563720_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NC_021194.1_1563847_1565059_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NC_021194.1_1565131_1566610_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NC_021194.1_1566606_1567992_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NC_021194.1_1568069_1569104_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NC_021194.1_1571134_1571536_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NC_021194.1_1571532_1571790_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NC_021194.1_1571872_1572832_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NC_021194.1_1572856_1573819_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NC_021194.1_1573952_1574555_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|275aa|down_5|NC_021194.1_1576618_1577443_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_6|NC_021194.1_1577611_1578094_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_7|NC_021194.1_1578165_1578990_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_8|NC_021194.1_1579186_1580125_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed	NA|458aa|down_9|NC_021194.1_1580121_1581495_+	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	9	1633780-1634109	3	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	NGCCGCCGGCNCCGCCGN	18	0	0	NA	NA	NA	6	6	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|80aa|up_8|NC_021194.1_1619789_1620029_+,NA|38aa|up_7|NC_021194.1_1620145_1620259_-,NA|137aa|up_6|NC_021194.1_1620308_1620719_-,NA|72aa|up_2|NC_021194.1_1627411_1627627_-,NA|288aa|down_2|NC_021194.1_1637700_1638564_+	NA|162aa|up_9|NC_021194.1_1619228_1619714_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|80aa|up_8|NC_021194.1_1619789_1620029_+	NA	NA|38aa|up_7|NC_021194.1_1620145_1620259_-	NA	NA|137aa|up_6|NC_021194.1_1620308_1620719_-	NA	NA|248aa|up_5|NC_021194.1_1620735_1621479_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|374aa|up_4|NC_021194.1_1623979_1625101_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_3|NC_021194.1_1625117_1627220_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|72aa|up_2|NC_021194.1_1627411_1627627_-	NA	NA|1330aa|up_1|NC_021194.1_1627658_1631648_-	pfam00934, PE, PE family	NA|309aa|up_0|NC_021194.1_1632049_1632976_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NC_021194.1_1635401_1636667_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NC_021194.1_1636694_1637681_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NC_021194.1_1637700_1638564_+	NA	NA|311aa|down_3|NC_021194.1_1638513_1639446_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NC_021194.1_1639557_1640343_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|302aa|down_5|NC_021194.1_1640339_1641245_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NC_021194.1_1641379_1643155_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NC_021194.1_1643202_1644009_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NC_021194.1_1644005_1646546_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NC_021194.1_1646542_1647736_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	10	2082516-2082770	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2082597-2082614|2082597-2082614|2082687-2082704	NC_021194.1_401007-400990|NC_021194.1_607332-607315|NC_021194.1_3435992-3435975	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|67aa|up_3|NC_021194.1_2078785_2078986_+,NA|88aa|up_0|NC_021194.1_2081875_2082139_-,NA	NA|226aa|up_9|NC_021194.1_2069067_2069745_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_8|NC_021194.1_2070103_2072929_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_7|NC_021194.1_2073155_2074016_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_6|NC_021194.1_2074056_2074923_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_5|NC_021194.1_2074927_2076814_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_4|NC_021194.1_2076829_2078863_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|67aa|up_3|NC_021194.1_2078785_2078986_+	NA	NA|742aa|up_2|NC_021194.1_2078982_2081208_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NC_021194.1_2081483_2081879_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NC_021194.1_2081875_2082139_-	NA	NA|456aa|down_0|NC_021194.1_2084943_2086311_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_1|NC_021194.1_2086484_2087921_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_2|NC_021194.1_2087956_2089408_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_3|NC_021194.1_2089437_2090388_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_4|NC_021194.1_2090402_2090819_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_5|NC_021194.1_2091096_2091519_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_6|NC_021194.1_2091567_2091870_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_7|NC_021194.1_2091866_2092181_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_8|NC_021194.1_2092180_2093914_+	PRK13206, ureC, urease subunit alpha; Reviewed	NA|212aa|down_9|NC_021194.1_2093913_2094549_+	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	11	2163034-2163253	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NC_021194.1_2154141_2154549_-,NA|127aa|down_5|NC_021194.1_2170769_2171150_-	NA|216aa|up_9|NC_021194.1_2147455_2148103_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NC_021194.1_2148109_2150332_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NC_021194.1_2150369_2150813_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NC_021194.1_2150926_2151520_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NC_021194.1_2151602_2152208_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NC_021194.1_2152307_2153312_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NC_021194.1_2153411_2154164_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NC_021194.1_2154141_2154549_-	NA	NA|368aa|up_1|NC_021194.1_2154683_2155787_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NC_021194.1_2155786_2156983_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|155aa|down_0|NC_021194.1_2165280_2165745_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NC_021194.1_2165842_2166706_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NC_021194.1_2166743_2168015_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NC_021194.1_2168286_2169402_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NC_021194.1_2169392_2170733_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NC_021194.1_2170769_2171150_-	NA	NA|621aa|down_6|NC_021194.1_2171306_2173169_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NC_021194.1_2173176_2173656_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NC_021194.1_2173892_2174666_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NC_021194.1_2174669_2175437_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	12	3105094-3106449	3,6,5	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-A,Type III-D,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	16,17,18	18	TypeIII-C,TypeIII-A,TypeIII-D,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|135aa|up_7|NC_021194.1_3098775_3099180_+,NA|64aa|up_6|NC_021194.1_3099176_3099368_+,NA|86aa|up_4|NC_021194.1_3100954_3101212_+,NA|104aa|up_3|NC_021194.1_3101316_3101628_+,NA|203aa|up_2|NC_021194.1_3102047_3102656_+,NA	NA|92aa|up_9|NC_021194.1_3097922_3098198_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|122aa|up_8|NC_021194.1_3098337_3098703_+	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain	NA|135aa|up_7|NC_021194.1_3098775_3099180_+	NA	NA|64aa|up_6|NC_021194.1_3099176_3099368_+	NA	NA|385aa|up_5|NC_021194.1_3099566_3100721_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NC_021194.1_3100954_3101212_+	NA	NA|104aa|up_3|NC_021194.1_3101316_3101628_+	NA	NA|203aa|up_2|NC_021194.1_3102047_3102656_+	NA	NA|470aa|up_1|NC_021194.1_3102726_3104136_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NC_021194.1_3104132_3104945_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NC_021194.1_3106475_3107737_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NC_021194.1_3109530_3109872_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NC_021194.1_3109872_3110889_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|53aa|down_3|NC_021194.1_3110901_3111060_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm6|291aa|down_4|NC_021194.1_3111176_3112049_-	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6	csm5gr7|376aa|down_5|NC_021194.1_3112144_3113272_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_6|NC_021194.1_3113268_3114177_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_7|NC_021194.1_3114157_3114868_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_8|NC_021194.1_3114877_3115252_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_9|NC_021194.1_3115248_3117678_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	13	3107772-3109482	7,6,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-A,Type III-D,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-C,TypeIII-A,TypeIII-D,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|135aa|up_8|NC_021194.1_3098775_3099180_+,NA|64aa|up_7|NC_021194.1_3099176_3099368_+,NA|86aa|up_5|NC_021194.1_3100954_3101212_+,NA|104aa|up_4|NC_021194.1_3101316_3101628_+,NA|203aa|up_3|NC_021194.1_3102047_3102656_+,NA	NA|122aa|up_9|NC_021194.1_3098337_3098703_+	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain	NA|135aa|up_8|NC_021194.1_3098775_3099180_+	NA	NA|64aa|up_7|NC_021194.1_3099176_3099368_+	NA	NA|385aa|up_6|NC_021194.1_3099566_3100721_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NC_021194.1_3100954_3101212_+	NA	NA|104aa|up_4|NC_021194.1_3101316_3101628_+	NA	NA|203aa|up_3|NC_021194.1_3102047_3102656_+	NA	NA|470aa|up_2|NC_021194.1_3102726_3104136_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NC_021194.1_3104132_3104945_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NC_021194.1_3106475_3107737_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NC_021194.1_3109530_3109872_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NC_021194.1_3109872_3110889_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|53aa|down_2|NC_021194.1_3110901_3111060_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm6|291aa|down_3|NC_021194.1_3111176_3112049_-	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6	csm5gr7|376aa|down_4|NC_021194.1_3112144_3113272_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NC_021194.1_3113268_3114177_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NC_021194.1_3114157_3114868_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NC_021194.1_3114877_3115252_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|810aa|down_8|NC_021194.1_3115248_3117678_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_9|NC_021194.1_3117674_3118619_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	14	3329014-3329281	7	CRT	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	GGNGCCTTGGTCGCCNNCTT	20	1	1	3329034-3329055	NC_021194.1_566258-566237	NA	5	5	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|228aa|up_9|NC_021194.1_3317871_3318555_-	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional	NA|334aa|up_8|NC_021194.1_3318587_3319589_-	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional	c2c9_V-U4|460aa|up_7|NC_021194.1_3319585_3320965_-	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|195aa|up_6|NC_021194.1_3320964_3321549_-	COG2452, COG2452, Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]	NA|182aa|up_5|NC_021194.1_3321760_3322306_+	pfam12028, DUF3515, Protein of unknown function (DUF3515)	NA|374aa|up_4|NC_021194.1_3322596_3323718_-	PRK01966, ddl, D-alanine--D-alanine ligase	NA|335aa|up_3|NC_021194.1_3323795_3324800_-	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA|215aa|up_2|NC_021194.1_3324918_3325563_+	COG1920, COG1920, Predicted nucleotidyltransferase, CobY/MobA/RfbA family [General function prediction only]	NA|743aa|up_1|NC_021194.1_3325654_3327883_+	PRK05443, PRK05443, polyphosphate kinase; Provisional	NA|318aa|up_0|NC_021194.1_3327965_3328919_+	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily	NA|199aa|down_0|NC_021194.1_3329829_3330426_-	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit	NA|474aa|down_1|NC_021194.1_3330450_3331872_-	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit	NA|234aa|down_2|NC_021194.1_3331943_3332645_+	COG1414, IclR, Transcriptional regulator [Transcription]	NA|287aa|down_3|NC_021194.1_3332655_3333516_-	cd02440, AdoMet_MTases, S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)	NA|164aa|down_4|NC_021194.1_3333778_3334270_+	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme	NA|491aa|down_5|NC_021194.1_3334601_3336074_-	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed	NA|266aa|down_6|NC_021194.1_3336070_3336868_-	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]	NA|337aa|down_7|NC_021194.1_3338254_3339265_-	PRK03437, PRK03437, 3-isopropylmalate dehydrogenase; Provisional	NA|529aa|down_8|NC_021194.1_3339279_3340866_-	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional	NA|481aa|down_9|NC_021194.1_3340895_3342338_+	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	15	3722326-3722867	8	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|160aa|up_9|NC_021194.1_3702399_3702879_+,NA|96aa|down_3|NC_021194.1_3736964_3737252_-,NA|87aa|down_7|NC_021194.1_3750359_3750620_-	NA|160aa|up_9|NC_021194.1_3702399_3702879_+	NA	NA|147aa|up_8|NC_021194.1_3702897_3703338_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NC_021194.1_3703371_3704241_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NC_021194.1_3704261_3705272_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NC_021194.1_3705556_3706189_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NC_021194.1_3706255_3707485_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NC_021194.1_3707767_3709117_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NC_021194.1_3709128_3710268_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NC_021194.1_3710264_3710996_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NC_021194.1_3711004_3718576_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NC_021194.1_3724838_3725096_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|149aa|down_1|NC_021194.1_3735446_3735893_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|273aa|down_2|NC_021194.1_3735929_3736748_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_3|NC_021194.1_3736964_3737252_-	NA	NA|265aa|down_4|NC_021194.1_3748969_3749764_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_5|NC_021194.1_3749845_3750217_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|137aa|down_6|NC_021194.1_3750114_3750525_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_7|NC_021194.1_3750359_3750620_-	NA	NA|130aa|down_8|NC_021194.1_3750734_3751124_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|98aa|down_9|NC_021194.1_3751137_3751431_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	16	3927244-3928929	9	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCANCGGCGGCNNCGGCGGC	37	2	8	3927836-3927870|3927836-3927870|3927836-3927870|3927836-3927870|3927836-3927870|3928727-3928752|3928727-3928752|3928727-3928752	NC_021194.1_3925952-3925986|NC_021194.1_3926294-3926328|NC_021194.1_3926885-3926919|NC_021194.1_3927236-3927270|NC_021194.1_3911690-3911724|NC_021194.1_3920143-3920168|NC_021194.1_3920479-3920504|NC_021194.1_3920825-3920850	NA	20	20	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|73aa|down_0|NC_021194.1_3929484_3929703_-,NA|280aa|down_3|NC_021194.1_3932303_3933143_+	NA|318aa|up_9|NC_021194.1_3899971_3900925_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NC_021194.1_3900949_3901141_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NC_021194.1_3901355_3902558_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NC_021194.1_3902582_3903704_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NC_021194.1_3903774_3905283_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1382aa|up_4|NC_021194.1_3905453_3909599_+	pfam00934, PE, PE family	NA|1902aa|up_3|NC_021194.1_3909889_3915595_+	pfam00934, PE, PE family	NA|516aa|up_2|NC_021194.1_3915761_3917309_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NC_021194.1_3917305_3918142_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NC_021194.1_3923971_3924628_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|73aa|down_0|NC_021194.1_3929484_3929703_-	NA	NA|549aa|down_1|NC_021194.1_3929699_3931346_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|263aa|down_2|NC_021194.1_3931419_3932208_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_3|NC_021194.1_3932303_3933143_+	NA	NA|399aa|down_4|NC_021194.1_3933197_3934394_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_5|NC_021194.1_3934422_3935133_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_6|NC_021194.1_3935197_3936241_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_7|NC_021194.1_3936393_3937305_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_8|NC_021194.1_3937320_3938385_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_9|NC_021194.1_3938401_3939586_+	PRK08313, PRK08313, thiolase domain-containing protein
GCF_000389945.1_ASM38994v1	NC_021194	Mycobacterium tuberculosis EAI5/NITR206, complete genome	17	4089505-4089593	8	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|65aa|up_7|NC_021194.1_4078196_4078391_+,NA|119aa|up_2|NC_021194.1_4085996_4086353_+,NA|233aa|up_0|NC_021194.1_4088609_4089308_-,NA|126aa|down_6|NC_021194.1_4094828_4095206_+	NA|388aa|up_9|NC_021194.1_4075762_4076926_-	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase	NA|351aa|up_8|NC_021194.1_4076922_4077975_-	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein	NA|65aa|up_7|NC_021194.1_4078196_4078391_+	NA	NA|288aa|up_6|NC_021194.1_4078473_4079337_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|288aa|up_5|NC_021194.1_4082501_4083365_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_4|NC_021194.1_4083357_4084284_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_3|NC_021194.1_4084285_4085911_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_2|NC_021194.1_4085996_4086353_+	NA	NA|652aa|up_1|NC_021194.1_4086618_4088574_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NC_021194.1_4088609_4089308_-	NA	NA|173aa|down_0|NC_021194.1_4089653_4090172_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NC_021194.1_4090172_4091156_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NC_021194.1_4091148_4092342_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NC_021194.1_4092347_4093169_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NC_021194.1_4093300_4093984_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NC_021194.1_4093983_4094721_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NC_021194.1_4094828_4095206_+	NA	NA|225aa|down_7|NC_021194.1_4095304_4095979_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NC_021194.1_4096084_4096879_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NC_021194.1_4096885_4097341_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
