assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	1	469112-469354	1	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GGAGAAGCACCGAGCGGAGAAGCACCG	27	0	0	NA	NA	NA	4	4	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|257aa|up_9|NC_015977.1_462499_463270_+,NA|80aa|up_8|NC_015977.1_463389_463629_-,NA|286aa|down_1|NC_015977.1_472111_472969_-,NA|74aa|down_6|NC_015977.1_478735_478957_+,NA|79aa|down_7|NC_015977.1_479026_479263_+	NA|257aa|up_9|NC_015977.1_462499_463270_+	NA	NA|80aa|up_8|NC_015977.1_463389_463629_-	NA	NA|74aa|up_7|NC_015977.1_463985_464207_+	pfam13711, DUF4160, Domain of unknown function (DUF4160)	NA|92aa|up_6|NC_015977.1_464220_464496_+	pfam10387, DUF2442, Protein of unknown function (DUF2442)	NA|166aa|up_5|NC_015977.1_464894_465392_-	COG0679, COG0679, Predicted permeases [General function prediction only]	NA|293aa|up_4|NC_015977.1_466039_466918_+	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]	NA|106aa|up_3|NC_015977.1_466929_467247_+	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin	NA|147aa|up_2|NC_015977.1_467493_467934_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|114aa|up_1|NC_015977.1_468015_468357_+	pfam14018, DUF4234, Domain of unknown function (DUF4234)	NA|129aa|up_0|NC_015977.1_468374_468761_+	pfam10825, DUF2752, Protein of unknown function (DUF2752)	NA|184aa|down_0|NC_015977.1_471534_472086_+	cd04692, Nudix_Hydrolase_33, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|286aa|down_1|NC_015977.1_472111_472969_-	NA	NA|309aa|down_2|NC_015977.1_473143_474070_+	cd02801, DUS_like_FMN, Dihydrouridine synthase-like (DUS-like) FMN-binding domain	NA|306aa|down_3|NC_015977.1_474256_475174_+	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|743aa|down_4|NC_015977.1_475576_477805_+	cd01678, PFL1, Pyruvate formate lyase 1	NA|254aa|down_5|NC_015977.1_477949_478711_+	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme	NA|74aa|down_6|NC_015977.1_478735_478957_+	NA	NA|79aa|down_7|NC_015977.1_479026_479263_+	NA	NA|584aa|down_8|NC_015977.1_479331_481083_+	COG4866, COG4866, Uncharacterized conserved protein [Function unknown]	NA|177aa|down_9|NC_015977.1_481201_481732_+	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	2	645150-645242	2	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	TTCAAGTCCTGTTACCCGCAGTAGAGCAGGAGA	33	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|61aa|up_7|NC_015977.1_637200_637383_+,NA|98aa|up_0|NC_015977.1_644711_645005_+,NA|100aa|down_0|NC_015977.1_645419_645719_-,NA|200aa|down_6|NC_015977.1_652432_653032_+	NA|413aa|up_9|NC_015977.1_633387_634626_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|760aa|up_8|NC_015977.1_634664_636944_+	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor	NA|61aa|up_7|NC_015977.1_637200_637383_+	NA	NA|99aa|up_6|NC_015977.1_637510_637807_+	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein	NA|391aa|up_5|NC_015977.1_637871_639044_+	COG0116, COG0116, Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]	NA|569aa|up_4|NC_015977.1_639040_640747_+	pfam18560, Lectin_like, Lectin like domain	NA|198aa|up_3|NC_015977.1_641827_642421_+	pfam01725, Ham1p_like, Ham1 family	NA|160aa|up_2|NC_015977.1_642424_642904_+	COG0622, COG0622, Predicted phosphoesterase [General function prediction only]	NA|193aa|up_1|NC_015977.1_643843_644422_+	TIGR04518, conserved_hypothetical_protein, ECF transporter S component, folate family	NA|98aa|up_0|NC_015977.1_644711_645005_+	NA	NA|100aa|down_0|NC_015977.1_645419_645719_-	NA	NA|304aa|down_1|NC_015977.1_646028_646940_+	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|359aa|down_2|NC_015977.1_646964_648041_+	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|336aa|down_3|NC_015977.1_648053_649061_+	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|347aa|down_4|NC_015977.1_649060_650101_+	PRK15079, PRK15079, oligopeptide ABC transporter ATP-binding protein OppF; Provisional	NA|587aa|down_5|NC_015977.1_650211_651972_+	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold	NA|200aa|down_6|NC_015977.1_652432_653032_+	NA	NA|765aa|down_7|NC_015977.1_653089_655384_+	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|329aa|down_8|NC_015977.1_655551_656538_+	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|555aa|down_9|NC_015977.1_656553_658218_+	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	3	707664-707754	3	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	CCCGTGAGAAAAAAGCAGTACGAAGCCG	28	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|76aa|up_3|NC_015977.1_703872_704100_+,NA	NA|507aa|up_9|NC_015977.1_694481_696002_+	COG3534, AbfA, Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]	NA|218aa|up_8|NC_015977.1_696032_696686_+	pfam04854, DUF624, Protein of unknown function, DUF624	NA|637aa|up_7|NC_015977.1_696699_698610_+	COG3533, COG3533, Uncharacterized protein conserved in bacteria [Function unknown]	NA|74aa|up_6|NC_015977.1_699300_699522_-	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type	NA|587aa|up_5|NC_015977.1_700029_701790_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|597aa|up_4|NC_015977.1_701904_703695_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|76aa|up_3|NC_015977.1_703872_704100_+	NA	NA|174aa|up_2|NC_015977.1_704084_704606_+	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle	NA|205aa|up_1|NC_015977.1_704702_705317_+	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive	NA|184aa|up_0|NC_015977.1_705646_706198_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|448aa|down_0|NC_015977.1_708239_709583_+	PRK01490, tig, trigger factor; Provisional	NA|202aa|down_1|NC_015977.1_709688_710294_+	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed	NA|420aa|down_2|NC_015977.1_710342_711602_+	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX	NA|776aa|down_3|NC_015977.1_711607_713935_+	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]	NA|199aa|down_4|NC_015977.1_713938_714535_+	PRK00454, engB, GTP-binding protein YsxC; Reviewed	NA|311aa|down_5|NC_015977.1_714810_715743_+	PRK12353, PRK12353, putative amino acid kinase; Reviewed	NA|593aa|down_6|NC_015977.1_715769_717548_+	PRK06354, PRK06354, pyruvate kinase; Provisional	NA|822aa|down_7|NC_015977.1_718230_720696_-	COG3459, COG3459, Cellobiose phosphorylase [Carbohydrate transport and metabolism]	NA|340aa|down_8|NC_015977.1_721159_722179_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|474aa|down_9|NC_015977.1_722249_723671_+	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	4	917237-917337	4	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GATGCCTCCCGGAAGTTCCACGGAA	25	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|137aa|up_7|NC_015977.1_908550_908961_+,NA|70aa|down_3|NC_015977.1_920908_921118_+	NA|227aa|up_9|NC_015977.1_907498_908179_+	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated	NA|162aa|up_8|NC_015977.1_908165_908651_+	pfam04892, VanZ, VanZ like family	NA|137aa|up_7|NC_015977.1_908550_908961_+	NA	NA|195aa|up_6|NC_015977.1_908970_909555_+	pfam13023, HD_3, HD domain	NA|679aa|up_5|NC_015977.1_909652_911689_+	COG2309, AmpS, Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]	NA|167aa|up_4|NC_015977.1_911903_912404_+	pfam00731, AIRC, AIR carboxylase	NA|342aa|up_3|NC_015977.1_912485_913511_+	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional	NA|209aa|up_2|NC_015977.1_913504_914131_+	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed	NA|426aa|up_1|NC_015977.1_914165_915443_+	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional	NA|277aa|up_0|NC_015977.1_915725_916556_-	COG0078, ArgF, Ornithine carbamoyltransferase [Amino acid transport and metabolism]	NA|504aa|down_0|NC_015977.1_917588_919100_+	pfam02074, Peptidase_M32, Carboxypeptidase Taq (M32) metallopeptidase	NA|221aa|down_1|NC_015977.1_919129_919792_+	COG0546, Gph, Predicted phosphatases [General function prediction only]	NA|326aa|down_2|NC_015977.1_919869_920847_+	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only]	NA|70aa|down_3|NC_015977.1_920908_921118_+	NA	NA|1073aa|down_4|NC_015977.1_921411_924630_+	PRK06039, ileS, isoleucyl-tRNA synthetase; Reviewed	NA|826aa|down_5|NC_015977.1_924630_927108_+	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins	NA|341aa|down_6|NC_015977.1_927362_928385_-	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP)	NA|342aa|down_7|NC_015977.1_928728_929754_+	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP)	NA|191aa|down_8|NC_015977.1_930607_931180_-	pfam02417, Chromate_transp, Chromate transporter	NA|190aa|down_9|NC_015977.1_931182_931752_-	pfam02417, Chromate_transp, Chromate transporter
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	5	1000886-1000992	5	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GCAGAAAGCAGCGCAAAAAGATGACATAAT	30	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|150aa|down_7|NC_015977.1_1008915_1009365_+	NA|231aa|up_9|NC_015977.1_989683_990376_+	PRK09283, PRK09283, porphobilinogen synthase	NA|424aa|up_8|NC_015977.1_990415_991687_+	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase	NA|395aa|up_7|NC_015977.1_991925_993110_+	TIGR03402, Cysteine_desulfurase_NifS, cysteine desulfurase NifS	NA|146aa|up_6|NC_015977.1_993136_993574_+	TIGR03419, NifU_clost, FeS cluster assembly scaffold protein NifU, Clostridium type	NA|195aa|up_5|NC_015977.1_993576_994161_+	pfam12993, DUF3877, Domain of unknown function, E	NA|141aa|up_4|NC_015977.1_994162_994585_+	COG1959, COG1959, Predicted transcriptional regulator [Transcription]	NA|150aa|up_3|NC_015977.1_994596_995046_+	TIGR00738, Putative_HTH-type_transcriptional_regulator, Rrf2 family protein	NA|604aa|up_2|NC_015977.1_995385_997197_+	PRK05433, PRK05433, GTP-binding protein LepA; Provisional	NA|411aa|up_1|NC_015977.1_997286_998519_+	PRK05799, PRK05799, oxygen-independent coproporphyrinogen III oxidase	NA|514aa|up_0|NC_015977.1_998750_1000292_+	cd10948, CE4_BsPdaA_like, Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs	NA|482aa|down_0|NC_015977.1_1001036_1002482_+	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)	NA|373aa|down_1|NC_015977.1_1002544_1003663_+	cd07383, MPP_Dcr2, Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain	NA|174aa|down_2|NC_015977.1_1003736_1004258_+	pfam04138, GtrA, GtrA-like protein	NA|82aa|down_3|NC_015977.1_1004698_1004944_+	TIGR03959, putative_iron-only_hydrogenase_system_regulator, putative iron-only hydrogenase system regulator	NA|362aa|down_4|NC_015977.1_1004967_1006053_+	TIGR03956, iron-only_hydrogenase_maturation_rSAM_protein_HydE, [FeFe] hydrogenase H-cluster radical SAM maturase HydE	NA|475aa|down_5|NC_015977.1_1006078_1007503_+	TIGR03955, iron-only_hydrogenase_maturation_rSAM_protein_HydG, [FeFe] hydrogenase H-cluster radical SAM maturase HydG	NA|408aa|down_6|NC_015977.1_1007602_1008826_+	TIGR03918, hydrogenase_maturation_GTPase_HydF, [FeFe] hydrogenase H-cluster maturation GTPase HydF	NA|150aa|down_7|NC_015977.1_1008915_1009365_+	NA	NA|202aa|down_8|NC_015977.1_1009526_1010132_+	pfam13189, Cytidylate_kin2, Cytidylate kinase-like family	NA|456aa|down_9|NC_015977.1_1010211_1011579_+	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism]
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	6	1044685-1044819	6	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GCGGGAAGCAGTTCCGGAAGCAG	23	1	1	1044772-1044796	NC_015977.1_1044796-1044820	NA	2	2	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|71aa|up_9|NC_015977.1_1025558_1025771_+,NA|137aa|up_5|NC_015977.1_1032927_1033338_+,NA|68aa|up_1|NC_015977.1_1042529_1042733_+,NA|244aa|down_4|NC_015977.1_1055251_1055983_+	NA|71aa|up_9|NC_015977.1_1025558_1025771_+	NA	NA|762aa|up_8|NC_015977.1_1025897_1028183_+	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]	NA|703aa|up_7|NC_015977.1_1028206_1030315_+	pfam12733, Cadherin-like, Cadherin-like beta sandwich domain	NA|818aa|up_6|NC_015977.1_1030353_1032807_+	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]	NA|137aa|up_5|NC_015977.1_1032927_1033338_+	NA	NA|457aa|up_4|NC_015977.1_1033514_1034885_+	PRK11823, PRK11823, DNA repair protein RadA; Provisional	NA|263aa|up_3|NC_015977.1_1041066_1041855_+	COG1342, COG1342, Predicted DNA-binding proteins [General function prediction only]	NA|207aa|up_2|NC_015977.1_1041876_1042497_+	pfam14199, DUF4317, Domain of unknown function (DUF4317)	NA|68aa|up_1|NC_015977.1_1042529_1042733_+	NA	NA|257aa|up_0|NC_015977.1_1042826_1043597_+	pfam07486, Hydrolase_2, Cell Wall Hydrolase	NA|308aa|down_0|NC_015977.1_1045309_1046233_+	pfam00480, ROK, ROK family	NA|547aa|down_1|NC_015977.1_1046366_1048007_-	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional	NA|1046aa|down_2|NC_015977.1_1048268_1051406_+	cd01948, EAL, EAL domain	NA|1182aa|down_3|NC_015977.1_1051546_1055092_+	TIGR02176, pyruvate_flavodoxin/ferrodoxin_oxidoreductase, pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric	NA|244aa|down_4|NC_015977.1_1055251_1055983_+	NA	NA|170aa|down_5|NC_015977.1_1056072_1056582_+	smart00471, HDc, Metal dependent phosphohydrolases with conserved 'HD' motif	NA|645aa|down_6|NC_015977.1_1057219_1059154_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|583aa|down_7|NC_015977.1_1059153_1060902_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|162aa|down_8|NC_015977.1_1061027_1061513_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|731aa|down_9|NC_015977.1_1061644_1063837_+	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	7	1074818-1074893	7	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GGCCTGGCAGGTGGACGGCTATTA	24	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|84aa|up_8|NC_015977.1_1064508_1064760_+,NA|414aa|up_7|NC_015977.1_1064850_1066092_+,NA|44aa|up_5|NC_015977.1_1066937_1067069_-,NA|170aa|up_0|NC_015977.1_1073151_1073661_-,NA|288aa|down_6|NC_015977.1_1082696_1083560_+	NA|173aa|up_9|NC_015977.1_1063908_1064427_+	pfam13353, Fer4_12, 4Fe-4S single cluster domain	NA|84aa|up_8|NC_015977.1_1064508_1064760_+	NA	NA|414aa|up_7|NC_015977.1_1064850_1066092_+	NA	NA|207aa|up_6|NC_015977.1_1066227_1066848_+	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only]	NA|44aa|up_5|NC_015977.1_1066937_1067069_-	NA	NA|252aa|up_4|NC_015977.1_1067253_1068009_+	cd06583, PGRP, Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls	NA|500aa|up_3|NC_015977.1_1068042_1069542_+	COG1041, COG1041, Predicted DNA modification methylase [DNA replication, recombination, and repair]	NA|884aa|up_2|NC_015977.1_1069549_1072201_+	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]	NA|189aa|up_1|NC_015977.1_1072550_1073117_-	pfam13189, Cytidylate_kin2, Cytidylate kinase-like family	NA|170aa|up_0|NC_015977.1_1073151_1073661_-	NA	NA|602aa|down_0|NC_015977.1_1074929_1076735_+	PRK05667, dnaG, DNA primase; Validated	NA|403aa|down_1|NC_015977.1_1076818_1078027_+	PRK09210, PRK09210, RNA polymerase sigma factor RpoD; Validated	NA|241aa|down_2|NC_015977.1_1078030_1078753_+	pfam12847, Methyltransf_18, Methyltransferase domain	NA|561aa|down_3|NC_015977.1_1078793_1080476_+	cd02028, UMPK_like, Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2	NA|361aa|down_4|NC_015977.1_1081062_1082145_+	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]	NA|136aa|down_5|NC_015977.1_1082262_1082670_+	pfam13386, DsbD_2, Cytochrome C biogenesis protein transmembrane region	NA|288aa|down_6|NC_015977.1_1082696_1083560_+	NA	NA|213aa|down_7|NC_015977.1_1083575_1084214_+	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ	NA|351aa|down_8|NC_015977.1_1084500_1085553_+	PRK00082, hrcA, heat-inducible transcription repressor; Provisional	NA|213aa|down_9|NC_015977.1_1085587_1086226_+	cd00446, GrpE, nucleotide exchange factor GrpE
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	8	1465451-1465544	8	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	AGCATTTGAAAATGTGACAGGAA	23	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|197aa|down_0|NC_015977.1_1467113_1467704_-,NA|51aa|down_5|NC_015977.1_1471801_1471954_+	NA|420aa|up_9|NC_015977.1_1453454_1454714_-	cd03682, ClC_sycA_like, ClC sycA-like chloride channel proteins	NA|73aa|up_8|NC_015977.1_1454966_1455185_+	COG1476, COG1476, Predicted transcriptional regulators [Transcription]	NA|269aa|up_7|NC_015977.1_1455205_1456012_+	pfam11368, DUF3169, Protein of unknown function (DUF3169)	NA|478aa|up_6|NC_015977.1_1456826_1458260_+	pfam13416, SBP_bac_8, Bacterial extracellular solute-binding protein	NA|281aa|up_5|NC_015977.1_1458378_1459221_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|291aa|up_4|NC_015977.1_1459220_1460093_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|339aa|up_3|NC_015977.1_1460143_1461160_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|503aa|up_2|NC_015977.1_1461170_1462679_+	PRK14508, PRK14508, 4-alpha-glucanotransferase; Provisional	NA|313aa|up_1|NC_015977.1_1462867_1463806_+	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]	NA|495aa|up_0|NC_015977.1_1463939_1465424_+	pfam09547, Spore_IV_A, Stage IV sporulation protein A (spore_IV_A)	NA|197aa|down_0|NC_015977.1_1467113_1467704_-	NA	NA|215aa|down_1|NC_015977.1_1467948_1468593_+	COG2364, COG2364, Predicted membrane protein [Function unknown]	NA|276aa|down_2|NC_015977.1_1468664_1469492_+	cd09009, PNP-EcPNPII_like, purine nucleoside phosphorylases similar to human PNP and Escherichia coli PNP-II (XapA)	NA|433aa|down_3|NC_015977.1_1469576_1470875_+	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases	NA|252aa|down_4|NC_015977.1_1470931_1471687_+	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]	NA|51aa|down_5|NC_015977.1_1471801_1471954_+	NA	NA|887aa|down_6|NC_015977.1_1471991_1474652_+	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed	NA|431aa|down_7|NC_015977.1_1474827_1476120_+	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)	NA|59aa|down_8|NC_015977.1_1476260_1476437_+	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed	NA|213aa|down_9|NC_015977.1_1476570_1477209_-	pfam02589, LUD_dom, LUD domain
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	9	1849044-1849141	9	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	CGACGATCCCCGTTCATCGGACGGCGGTC	29	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA	NA|387aa|up_9|NC_015977.1_1835616_1836777_+	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]	NA|512aa|up_8|NC_015977.1_1836787_1838323_-	cd09160, PLDc_SMU_988_like_2, Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins	NA|303aa|up_7|NC_015977.1_1838474_1839383_-	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1	NA|698aa|up_6|NC_015977.1_1839467_1841561_-	PRK11824, PRK11824, polynucleotide phosphorylase/polyadenylase; Provisional	NA|89aa|up_5|NC_015977.1_1841812_1842079_-	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed	NA|421aa|up_4|NC_015977.1_1842256_1843519_-	pfam00877, NLPC_P60, NlpC/P60 family	NA|309aa|up_3|NC_015977.1_1843646_1844573_-	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase	NA|308aa|up_2|NC_015977.1_1844576_1845500_-	PRK00130, truB, tRNA pseudouridine synthase B; Provisional	NA|317aa|up_1|NC_015977.1_1845512_1846463_-	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only]	NA|132aa|up_0|NC_015977.1_1846459_1846855_-	pfam02033, RBFA, Ribosome-binding factor A	NA|107aa|down_0|NC_015977.1_1849866_1850187_-	PRK07714, PRK07714, YlxQ family RNA-binding protein	NA|97aa|down_1|NC_015977.1_1850173_1850464_-	pfam04296, DUF448, Protein of unknown function (DUF448)	NA|414aa|down_2|NC_015977.1_1850482_1851724_-	PRK12327, nusA, transcription elongation factor NusA; Provisional	NA|156aa|down_3|NC_015977.1_1851769_1852237_-	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed	NA|157aa|down_4|NC_015977.1_1852432_1852903_-	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS)	NA|339aa|down_5|NC_015977.1_1853937_1854954_-	PLN02240, PLN02240, UDP-glucose 4-epimerase	NA|277aa|down_6|NC_015977.1_1855148_1855979_+	cd06986, cupin_MmsR-like_N, AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain	NA|240aa|down_7|NC_015977.1_1855979_1856699_-	cd07432, PHP_HisPPase, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase	NA|150aa|down_8|NC_015977.1_1856715_1857165_-	pfam08863, YolD, YolD-like protein	NA|487aa|down_9|NC_015977.1_1857164_1858625_-	cd01700, PolY_Pol_V_umuC, umuC subunit of DNA Polymerase V
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	10	2204732-2204831	10	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GCGGGTTGCATGCATACTTTCCTCTGTCTGGCTT	34	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA|60aa|up_3|NC_015977.1_2200876_2201056_-,NA|287aa|up_2|NC_015977.1_2201745_2202606_-,NA|136aa|up_1|NC_015977.1_2202808_2203216_-,NA|72aa|down_0|NC_015977.1_2205163_2205379_-,NA|107aa|down_8|NC_015977.1_2218011_2218332_-	NA|318aa|up_9|NC_015977.1_2192080_2193034_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|198aa|up_8|NC_015977.1_2193036_2193630_-	cd03674, Nudix_Hydrolase_1, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|444aa|up_7|NC_015977.1_2193811_2195143_-	PRK05159, aspC, aspartyl-tRNA synthetase; Provisional	NA|166aa|up_6|NC_015977.1_2195693_2196191_-	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase	NA|248aa|up_5|NC_015977.1_2197459_2198203_-	pfam01420, Methylase_S, Type I restriction modification DNA specificity domain	NA|796aa|up_4|NC_015977.1_2198496_2200884_-	pfam02384, N6_Mtase, N-6 DNA Methylase	NA|60aa|up_3|NC_015977.1_2200876_2201056_-	NA	NA|287aa|up_2|NC_015977.1_2201745_2202606_-	NA	NA|136aa|up_1|NC_015977.1_2202808_2203216_-	NA	NA|310aa|up_0|NC_015977.1_2203511_2204441_-	PRK06522, PRK06522, 2-dehydropantoate 2-reductase; Reviewed	NA|72aa|down_0|NC_015977.1_2205163_2205379_-	NA	NA|200aa|down_1|NC_015977.1_2205368_2205968_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|456aa|down_2|NC_015977.1_2206566_2207934_+	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA	NA|703aa|down_3|NC_015977.1_2207982_2210091_-	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]	NA|535aa|down_4|NC_015977.1_2210450_2212055_+	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase	NA|572aa|down_5|NC_015977.1_2212690_2214406_-	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)	NA|400aa|down_6|NC_015977.1_2214448_2215648_-	cd19963, PBP1_BMP-like, periplasmic binding component of a basic membrane lipoprotein (BMP) from Brucella abortus and its close homologs in other bacteria	NA|692aa|down_7|NC_015977.1_2215912_2217988_-	cd07550, P-type_ATPase_HM, P-type heavy metal-transporting ATPase; uncharacterized subfamily	NA|107aa|down_8|NC_015977.1_2218011_2218332_-	NA	NA|146aa|down_9|NC_015977.1_2218638_2219076_-	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	11	2304874-2304992	11	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	TCGGGTCTACAGCCGATAAAATACGCCGTGAGACCCG	37	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|63aa|down_8|NC_015977.1_2317931_2318120_-	NA|88aa|up_9|NC_015977.1_2286090_2286354_-	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism]	NA|261aa|up_8|NC_015977.1_2286372_2287155_-	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|261aa|up_7|NC_015977.1_2287254_2288037_-	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]	NA|210aa|up_6|NC_015977.1_2288198_2288828_-	pfam12672, DUF3793, Protein of unknown function (DUF3793)	NA|267aa|up_5|NC_015977.1_2289214_2290015_-	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|1013aa|up_4|NC_015977.1_2291922_2294961_-	PRK10340, ebgA, cryptic beta-D-galactosidase subunit alpha; Reviewed	NA|288aa|up_3|NC_015977.1_2295160_2296024_+	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|169aa|up_2|NC_015977.1_2296096_2296603_-	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|635aa|up_1|NC_015977.1_2296616_2298521_-	cd03230, ABC_DR_subfamily_A, ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A	NA|2041aa|up_0|NC_015977.1_2298520_2304643_-	pfam13191, AAA_16, AAA ATPase domain	NA|456aa|down_0|NC_015977.1_2305270_2306638_-	cd13134, MATE_like_8, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins	NA|734aa|down_1|NC_015977.1_2306760_2308962_-	pfam17389, Bac_rhamnosid6H, Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	NA|274aa|down_2|NC_015977.1_2308999_2309821_-	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|735aa|down_3|NC_015977.1_2309872_2312077_-	PRK10150, PRK10150, beta-D-glucuronidase; Provisional	NA|498aa|down_4|NC_015977.1_2312107_2313601_-	pfam13347, MFS_2, MFS/sugar transport protein	NA|439aa|down_5|NC_015977.1_2313884_2315201_+	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism]	NA|404aa|down_6|NC_015977.1_2315217_2316429_+	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|376aa|down_7|NC_015977.1_2316560_2317688_-	pfam02595, Gly_kinase, Glycerate kinase family	NA|63aa|down_8|NC_015977.1_2317931_2318120_-	NA	NA|235aa|down_9|NC_015977.1_2318164_2318869_-	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	12	2374871-2374974	12	CRISPRCasFinder	no		cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	GCTCCTCGCCGTGACAGTTCGATTCC	26	0	0	NA	NA	NA	1	1	Orphan	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|73aa|down_0|NC_015977.1_2375083_2375302_-,NA|617aa|down_1|NC_015977.1_2375274_2377125_-	NA|206aa|up_9|NC_015977.1_2361896_2362514_+	pfam08876, DUF1836, Domain of unknown function (DUF1836)	NA|99aa|up_8|NC_015977.1_2362578_2362875_-	TIGR02531, conserved_hypothetical_protein, TrpR-related protein YerC/YecD	NA|300aa|up_7|NC_015977.1_2363072_2363972_+	pfam02517, Abi, CAAX protease self-immunity	NA|354aa|up_6|NC_015977.1_2363934_2364996_-	PRK05387, PRK05387, histidinol-phosphate aminotransferase; Provisional	NA|404aa|up_5|NC_015977.1_2365007_2366219_-	PRK06836, PRK06836, pyridoxal phosphate-dependent aminotransferase	NA|521aa|up_4|NC_015977.1_2366426_2367989_-	PRK05270, PRK05270, UDP-glucose--hexose-1-phosphate uridylyltransferase	NA|390aa|up_3|NC_015977.1_2368021_2369191_-	PRK05322, PRK05322, galactokinase; Provisional	NA|371aa|up_2|NC_015977.1_2369412_2370525_-	COG3867, COG3867, Arabinogalactan endo-1,4-beta-galactosidase [Carbohydrate transport and metabolism]	NA|1060aa|up_1|NC_015977.1_2370581_2373761_-	PRK10340, ebgA, cryptic beta-D-galactosidase subunit alpha; Reviewed	NA|318aa|up_0|NC_015977.1_2373880_2374834_-	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|73aa|down_0|NC_015977.1_2375083_2375302_-	NA	NA|617aa|down_1|NC_015977.1_2375274_2377125_-	NA	NA|283aa|down_2|NC_015977.1_2377318_2378167_-	COG3833, MalG, ABC-type maltose transport systems, permease component [Carbohydrate transport and metabolism]	NA|484aa|down_3|NC_015977.1_2378166_2379618_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|436aa|down_4|NC_015977.1_2379821_2381129_-	cd13655, PBP2_oligosaccharide_1, The periplasmic binding component of ABC tansport system specific for an unknown oligosaccharide; possess the type 2 periplasmic binidng fold	NA|336aa|down_5|NC_015977.1_2381534_2382542_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|667aa|down_6|NC_015977.1_2382824_2384825_+	pfam02449, Glyco_hydro_42, Beta-galactosidase	NA|634aa|down_7|NC_015977.1_2385438_2387340_-	cd01948, EAL, EAL domain	NA|443aa|down_8|NC_015977.1_2387495_2388824_-	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB	NA|227aa|down_9|NC_015977.1_2388823_2389504_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein
GCF_000225345.1_ASM22534v1	NC_015977	Roseburia hominis A2-183, complete sequence	13	2759265-2764809	13,1,1,2	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas2,cas1,cas4,cas7,cas8c,cas5,cas3	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	 Type I-U?,Type I-U,Type I-C	ATTTCAATCCACGCTCCCCTCACAGGGAGCGAC,ATTTCAATCCACGCTCCCCTCACAGGGAGCGAC,ATTTCAATCCACGCTCCCCTCACAGGGAGCGAC,ATTTCAATCCACGCTCCCCTCACAGGGAGCGAC	33,33,33,33	0	0	NA	NA	NA:NA:NA:NA	82,80,78,78	82	TypeI-U?,TypeI-U,TypeI-C	cas3,PD-DExK,WYL,DEDDh,RT,csa3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA	NA|339aa|up_9|NC_015977.1_2748411_2749428_-	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD	NA|440aa|up_8|NC_015977.1_2749437_2750757_-	PRK09034, PRK09034, aspartate kinase; Reviewed	NA|266aa|up_7|NC_015977.1_2750890_2751688_-	cd07398, MPP_YbbF-LpxH, Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain	NA|313aa|up_6|NC_015977.1_2751692_2752631_-	pfam14751, DUF4474, Domain of unknown function (DUF4474)	NA|294aa|up_5|NC_015977.1_2752630_2753512_-	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan	NA|231aa|up_4|NC_015977.1_2753606_2754299_-	pfam04172, LrgB, LrgB-like family	NA|118aa|up_3|NC_015977.1_2754303_2754657_-	pfam03788, LrgA, LrgA family	NA|658aa|up_2|NC_015977.1_2754765_2756739_-	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS	NA|220aa|up_1|NC_015977.1_2756771_2757431_-	pfam03692, CxxCxxCC, Putative zinc- or iron-chelating domain	NA|399aa|up_0|NC_015977.1_2757582_2758779_-	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]	cas2|97aa|down_0|NC_015977.1_2764994_2765285_-	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	cas1|343aa|down_1|NC_015977.1_2765321_2766350_-	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG	cas4|222aa|down_2|NC_015977.1_2766346_2767012_-	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4	cas7|296aa|down_3|NC_015977.1_2767041_2767929_-	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7	cas8c|584aa|down_4|NC_015977.1_2767930_2769682_-	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1)	cas5|212aa|down_5|NC_015977.1_2769678_2770314_-	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas3|742aa|down_6|NC_015977.1_2770540_2772766_-	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3	NA|271aa|down_7|NC_015977.1_2773232_2774045_-	PRK00865, PRK00865, glutamate racemase; Provisional	NA|985aa|down_8|NC_015977.1_2774047_2777002_-	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair]	NA|386aa|down_9|NC_015977.1_2776998_2778156_-	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair]
