assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	1	70618-70717	1	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	ACTGCGGCTTTTCGGGGGCTCCGGGTGGCGGAGCCCC	37	1	4	70655-70680|70655-70680|70655-70680|70655-70680	NC_017186.1_1133588-1133613|NC_017186.1_7397402-7397427|NC_017186.1_2681746-2681721|NC_017186.1_8888569-8888544	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA	NA|154aa|up_9|NC_017186.1_59366_59828_-	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms]	NA|412aa|up_8|NC_017186.1_59928_61164_-	pfam12401, DUF3662, Protein of unknown function (DUF2662)	NA|244aa|up_7|NC_017186.1_61551_62283_-	smart00020, Tryp_SPc, Trypsin-like serine protease	NA|251aa|up_6|NC_017186.1_62398_63151_-	smart00020, Tryp_SPc, Trypsin-like serine protease	NA|125aa|up_5|NC_017186.1_63302_63677_-	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]	NA|1073aa|up_4|NC_017186.1_63818_67037_+	pfam01804, Penicil_amidase, Penicillin amidase	NA|347aa|up_3|NC_017186.1_67095_68136_+	cd00614, CGS_like, CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis	NA|262aa|up_2|NC_017186.1_68209_68995_+	PRK11907, PRK11907, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA|195aa|up_1|NC_017186.1_68991_69576_+	cd05829, Sortase_F, Sortase domain found in the class F family of sortases	NA|347aa|up_0|NC_017186.1_69561_70602_-	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|248aa|down_0|NC_017186.1_70722_71466_-	COG2186, FadR, Transcriptional regulators [Transcription]	NA|497aa|down_1|NC_017186.1_71593_73084_+	cd08494, PBP2_NikA_DppA_OppA_like_6, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|315aa|down_2|NC_017186.1_73080_74025_+	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|269aa|down_3|NC_017186.1_74024_74831_+	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|244aa|down_4|NC_017186.1_74827_75559_+	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|258aa|down_5|NC_017186.1_75555_76329_+	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|471aa|down_6|NC_017186.1_76321_77734_+	cd07149, ALDH_y4uC, Uncharacterized ALDH (y4uC) with similarity to Tortula ruralis aldehyde dehydrogenase ALDH21A1	NA|252aa|down_7|NC_017186.1_77730_78486_+	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase	NA|462aa|down_8|NC_017186.1_78495_79881_+	PRK07042, PRK07042, amidase; Provisional	NA|404aa|down_9|NC_017186.1_79953_81165_-	pfam01548, DEDD_Tnp_IS110, Transposase
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	2	301018-301110	2	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GGCTTTCACGGGGGTCCGGGTGGCGGAGCCCC	32	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|415aa|up_8|NC_017186.1_290622_291867_+,NA	NA|572aa|up_9|NC_017186.1_288419_290135_+	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX	NA|415aa|up_8|NC_017186.1_290622_291867_+	NA	NA|543aa|up_7|NC_017186.1_292075_293704_+	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites	NA|449aa|up_6|NC_017186.1_293700_295047_+	cd06543, GH18_PF-ChiA-like, PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain	NA|434aa|up_5|NC_017186.1_295161_296463_-	cd00610, OAT_like, Acetyl ornithine aminotransferase family	NA|306aa|up_4|NC_017186.1_296550_297468_+	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|348aa|up_3|NC_017186.1_297541_298585_-	sd00010, SLR, Sel1-like repeat	NA|224aa|up_2|NC_017186.1_298763_299435_+	pfam07510, DUF1524, Protein of unknown function (DUF1524)	NA|213aa|up_1|NC_017186.1_299445_300084_+	pfam12697, Abhydrolase_6, Alpha/beta hydrolase family	NA|248aa|up_0|NC_017186.1_300209_300953_+	cd14667, 3D_containing_proteins, Non-mltA associated 3D domain containing proteins, named for 3 conserved aspartate residues	NA|213aa|down_0|NC_017186.1_301134_301773_-	pfam00881, Nitroreductase, Nitroreductase family	NA|326aa|down_1|NC_017186.1_301791_302769_-	cd19086, AKR_AKR11C1, AKR11C family of aldo-keto reductase (AKR)	NA|167aa|down_2|NC_017186.1_302811_303312_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|140aa|down_3|NC_017186.1_303325_303745_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|260aa|down_4|NC_017186.1_303807_304587_-	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily	NA|139aa|down_5|NC_017186.1_304583_305000_-	TIGR01924, Serine-protein_kinase_RsbW, serine-protein kinase RsbW	NA|103aa|down_6|NC_017186.1_305163_305472_+	pfam02467, Whib, Transcription factor WhiB	NA|118aa|down_7|NC_017186.1_305690_306044_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|263aa|down_8|NC_017186.1_306103_306892_+	pfam04307, YdjM, LexA-binding, inner membrane-associated putative hydrolase	NA|144aa|down_9|NC_017186.1_307164_307596_-	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only]
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	3	763122-763205	3	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCGAGGAGACCACCGAGGCTCCGGCC	27	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|62aa|up_3|NC_017186.1_760229_760415_+,NA|240aa|down_1|NC_017186.1_764214_764934_-	NA|436aa|up_9|NC_017186.1_756336_757644_+	PRK09204, secY, preprotein translocase subunit SecY; Reviewed	NA|185aa|up_8|NC_017186.1_757640_758195_+	PRK00279, adk, adenylate kinase; Reviewed	NA|259aa|up_7|NC_017186.1_758239_759016_+	PRK05716, PRK05716, methionine aminopeptidase; Validated	NA|74aa|up_6|NC_017186.1_759273_759495_+	PRK00276, infA, translation initiation factor IF-1; Validated	NA|38aa|up_5|NC_017186.1_759532_759646_+	PRK00465, rpmJ, 50S ribosomal protein L36; Reviewed	NA|127aa|up_4|NC_017186.1_759852_760233_+	PRK05179, rpsM, 30S ribosomal protein S13; Validated	NA|62aa|up_3|NC_017186.1_760229_760415_+	NA	NA|136aa|up_2|NC_017186.1_760433_760841_+	PRK05309, PRK05309, 30S ribosomal protein S11; Validated	NA|202aa|up_1|NC_017186.1_760864_761470_+	PRK05327, rpsD, 30S ribosomal protein S4; Validated	NA|357aa|up_0|NC_017186.1_761577_762648_+	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional	NA|300aa|down_0|NC_017186.1_763245_764145_+	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA	NA|240aa|down_1|NC_017186.1_764214_764934_-	NA	NA|394aa|down_2|NC_017186.1_765007_766189_-	TIGR03923, T7SS_EccE, type VII secretion protein EccE	NA|546aa|down_3|NC_017186.1_766861_768499_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|101aa|down_4|NC_017186.1_768578_768881_+	PLN02935, PLN02935, Bifunctional NADH kinase/NAD(+) kinase	NA|359aa|down_5|NC_017186.1_768877_769954_+	pfam06013, WXG100, Proteins of 100 residues with WXG	NA|537aa|down_6|NC_017186.1_769963_771574_-	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin	NA|455aa|down_7|NC_017186.1_771594_772959_-	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD	NA|1338aa|down_8|NC_017186.1_773317_777331_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|664aa|down_9|NC_017186.1_777536_779528_+	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	4	1339607-1339682	4	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GGTGAGCCCGGCGGGGCGGGCCT	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|75aa|up_4|NC_017186.1_1335621_1335846_-,NA|70aa|down_0|NC_017186.1_1340025_1340235_+	NA|230aa|up_9|NC_017186.1_1331175_1331865_+	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning]	NA|298aa|up_8|NC_017186.1_1331911_1332805_+	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning]	NA|161aa|up_7|NC_017186.1_1332851_1333334_+	pfam01668, SmpB, SmpB protein	NA|299aa|up_6|NC_017186.1_1333330_1334227_+	pfam04909, Amidohydro_2, Amidohydrolase	NA|437aa|up_5|NC_017186.1_1334216_1335527_-	pfam01757, Acyl_transf_3, Acyltransferase family	NA|75aa|up_4|NC_017186.1_1335621_1335846_-	NA	NA|133aa|up_3|NC_017186.1_1336018_1336417_+	pfam03928, Haem_degrading, Haem-degrading	NA|214aa|up_2|NC_017186.1_1336401_1337043_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|378aa|up_1|NC_017186.1_1337082_1338216_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|225aa|up_0|NC_017186.1_1338212_1338887_-	pfam13796, Sensor, Putative sensor	NA|70aa|down_0|NC_017186.1_1340025_1340235_+	NA	NA|413aa|down_1|NC_017186.1_1340239_1341478_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|401aa|down_2|NC_017186.1_1341617_1342820_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|261aa|down_3|NC_017186.1_1342956_1343739_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|509aa|down_4|NC_017186.1_1343823_1345350_+	PRK09367, PRK09367, histidine ammonia-lyase; Provisional	NA|551aa|down_5|NC_017186.1_1345352_1347005_+	PRK05414, PRK05414, urocanate hydratase; Provisional	NA|399aa|down_6|NC_017186.1_1347001_1348198_+	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed	NA|452aa|down_7|NC_017186.1_1348194_1349550_+	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated	NA|382aa|down_8|NC_017186.1_1349537_1350683_+	PRK14085, PRK14085, imidazolonepropionase; Provisional	NA|384aa|down_9|NC_017186.1_1350796_1351948_+	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	5	1356881-1357109	1	CRT	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	TCGAGAGCACTGCTCNCG	18	0	0	NA	NA	NA	5	5	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|74aa|up_2|NC_017186.1_1355625_1355847_+,NA|249aa|up_1|NC_017186.1_1355828_1356575_-,NA|70aa|up_0|NC_017186.1_1356571_1356781_-,NA|263aa|down_5|NC_017186.1_1364448_1365237_-	NA|399aa|up_9|NC_017186.1_1347001_1348198_+	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed	NA|452aa|up_8|NC_017186.1_1348194_1349550_+	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated	NA|382aa|up_7|NC_017186.1_1349537_1350683_+	PRK14085, PRK14085, imidazolonepropionase; Provisional	NA|384aa|up_6|NC_017186.1_1350796_1351948_+	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]	NA|288aa|up_5|NC_017186.1_1351931_1352795_-	pfam01674, Lipase_2, Lipase (class 2)	NA|473aa|up_4|NC_017186.1_1352876_1354295_-	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed	NA|376aa|up_3|NC_017186.1_1354489_1355617_+	pfam01384, PHO4, Phosphate transporter family	NA|74aa|up_2|NC_017186.1_1355625_1355847_+	NA	NA|249aa|up_1|NC_017186.1_1355828_1356575_-	NA	NA|70aa|up_0|NC_017186.1_1356571_1356781_-	NA	NA|525aa|down_0|NC_017186.1_1357206_1358781_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|225aa|down_1|NC_017186.1_1358777_1359452_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|375aa|down_2|NC_017186.1_1359396_1360521_-	PRK06753, PRK06753, hypothetical protein; Provisional	NA|218aa|down_3|NC_017186.1_1360473_1361127_+	pfam17940, TetR_C_31, Tetracyclin repressor-like, C-terminal domain	NA|999aa|down_4|NC_017186.1_1361378_1364375_+	pfam00931, NB-ARC, NB-ARC domain	NA|263aa|down_5|NC_017186.1_1364448_1365237_-	NA	NA|305aa|down_6|NC_017186.1_1365233_1366148_-	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter	NA|798aa|down_7|NC_017186.1_1366219_1368613_-	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB	NA|277aa|down_8|NC_017186.1_1368609_1369440_-	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold	NA|169aa|down_9|NC_017186.1_1369527_1370034_+	pfam07291, MauE, Methylamine utilisation protein MauE
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	6	1632660-1632783	5	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCGTGGCGGAGCCGAGCTGCCGCGGTGG	29	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA	NA|381aa|up_9|NC_017186.1_1620159_1621302_+	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap	NA|340aa|up_8|NC_017186.1_1621464_1622484_-	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]	NA|464aa|up_7|NC_017186.1_1622483_1623875_-	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor	NA|490aa|up_6|NC_017186.1_1623871_1625341_-	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor	NA|256aa|up_5|NC_017186.1_1625766_1626534_+	pfam14023, DUF4239, Protein of unknown function (DUF4239)	NA|436aa|up_4|NC_017186.1_1626530_1627838_+	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional	NA|339aa|up_3|NC_017186.1_1627844_1628861_-	cd06302, PBP1_LsrB_Quorum_Sensing-like, periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs	NA|152aa|up_2|NC_017186.1_1629121_1629577_+	pfam14342, DUF4396, Domain of unknown function (DUF4396)	NA|416aa|up_1|NC_017186.1_1629614_1630862_-	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88	NA|408aa|up_0|NC_017186.1_1631079_1632303_-	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown]	NA|219aa|down_0|NC_017186.1_1635872_1636529_+	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown]	NA|524aa|down_1|NC_017186.1_1636560_1638132_+	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism]	NA|494aa|down_2|NC_017186.1_1638448_1639930_+	COG5434, PGU1, Endopygalactorunase [Cell envelope biogenesis, outer membrane]	NA|396aa|down_3|NC_017186.1_1640106_1641294_-	COG4225, COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]	NA|591aa|down_4|NC_017186.1_1641646_1643419_+	pfam01120, Alpha_L_fucos, Alpha-L-fucosidase	NA|410aa|down_5|NC_017186.1_1643459_1644689_-	PRK10137, PRK10137, alpha-glucosidase; Provisional	NA|385aa|down_6|NC_017186.1_1644750_1645905_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|644aa|down_7|NC_017186.1_1646208_1648140_+	cd04056, Peptidases_S53, Peptidase domain in the S53 family	NA|512aa|down_8|NC_017186.1_1648230_1649766_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|458aa|down_9|NC_017186.1_1649900_1651274_+	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	7	1931492-1931584	6	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCGGGCGTGCTCGGGTGGCATCGC	24	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|224aa|up_7|NC_017186.1_1925241_1925913_+,NA|145aa|up_0|NC_017186.1_1930984_1931419_+,NA|162aa|down_0|NC_017186.1_1931912_1932398_+,NA|393aa|down_1|NC_017186.1_1932394_1933573_+,NA|175aa|down_6|NC_017186.1_1937591_1938116_-	NA|231aa|up_9|NC_017186.1_1923985_1924678_+	cd00607, RNase_Sa, RNase_Sa	NA|167aa|up_8|NC_017186.1_1924741_1925242_+	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|224aa|up_7|NC_017186.1_1925241_1925913_+	NA	NA|243aa|up_6|NC_017186.1_1926025_1926754_+	COG3599, DivIVA, Cell division initiation protein [Cell division and chromosome partitioning]	NA|196aa|up_5|NC_017186.1_1926934_1927522_+	COG1399, COG1399, Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]	NA|61aa|up_4|NC_017186.1_1927609_1927792_+	PRK12286, rpmF, 50S ribosomal protein L32; Reviewed	NA|250aa|up_3|NC_017186.1_1927805_1928555_+	PRK00102, rnc, ribonuclease III; Reviewed	NA|452aa|up_2|NC_017186.1_1928642_1929998_+	cd14251, PL-6, Polysaccharide Lyase Family 6	NA|290aa|up_1|NC_017186.1_1930056_1930926_+	PRK01103, PRK01103, bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	NA|145aa|up_0|NC_017186.1_1930984_1931419_+	NA	NA|162aa|down_0|NC_017186.1_1931912_1932398_+	NA	NA|393aa|down_1|NC_017186.1_1932394_1933573_+	NA	NA|301aa|down_2|NC_017186.1_1933789_1934692_-	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism]	NA|108aa|down_3|NC_017186.1_1934789_1935113_+	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|409aa|down_4|NC_017186.1_1935109_1936336_+	pfam08006, DUF1700, Protein of unknown function (DUF1700)	NA|321aa|down_5|NC_017186.1_1936419_1937382_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|175aa|down_6|NC_017186.1_1937591_1938116_-	NA	NA|449aa|down_7|NC_017186.1_1938345_1939692_+	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism]	NA|235aa|down_8|NC_017186.1_1939693_1940398_+	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only]	NA|456aa|down_9|NC_017186.1_1940394_1941762_+	pfam00171, Aldedh, Aldehyde dehydrogenase family
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	8	2088131-2088553	2,7,1	CRT,CRISPRCasFinder,PILER-CR	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GNCGTGCGCAACCGCGAGTCCTGA,TGCGCAACCGCGAGTCCTGAGCC,CCGGAAGGAGAGCTGCCGTGCGCAACCGCGAGTCCTGAG	24,23,39	0	0	NA	NA	NA:NA:NA	6,6,2	6	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|221aa|up_2|NC_017186.1_2085382_2086045_-,NA|121aa|down_2|NC_017186.1_2090091_2090454_+	NA|285aa|up_9|NC_017186.1_2077417_2078272_+	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional	NA|209aa|up_8|NC_017186.1_2078268_2078895_-	pfam11575, FhuF_C, FhuF 2Fe-2S C-terminal domain	NA|233aa|up_7|NC_017186.1_2078913_2079612_-	PRK11088, rrmA, 23S rRNA methyltransferase A; Provisional	NA|463aa|up_6|NC_017186.1_2079935_2081324_+	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism]	NA|113aa|up_5|NC_017186.1_2081320_2081659_+	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism]	NA|770aa|up_4|NC_017186.1_2081669_2083979_+	PRK03381, PRK03381, PII uridylyl-transferase; Provisional	NA|444aa|up_3|NC_017186.1_2084058_2085390_-	PRK06834, PRK06834, hypothetical protein; Provisional	NA|221aa|up_2|NC_017186.1_2085382_2086045_-	NA	NA|201aa|up_1|NC_017186.1_2086041_2086644_-	TIGR03384, betaine_BetI, transcriptional repressor BetI	NA|435aa|up_0|NC_017186.1_2086712_2088017_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|251aa|down_0|NC_017186.1_2088607_2089360_-	PRK06172, PRK06172, SDR family oxidoreductase	NA|196aa|down_1|NC_017186.1_2089383_2089971_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|121aa|down_2|NC_017186.1_2090091_2090454_+	NA	NA|294aa|down_3|NC_017186.1_2090506_2091388_+	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku	NA|160aa|down_4|NC_017186.1_2091666_2092146_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|593aa|down_5|NC_017186.1_2092155_2093934_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|513aa|down_6|NC_017186.1_2094129_2095668_+	PRK10867, PRK10867, signal recognition particle protein; Provisional	NA|359aa|down_7|NC_017186.1_2095676_2096753_+	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site	NA|242aa|down_8|NC_017186.1_2096799_2097525_+	pfam02517, Abi, CAAX protease self-immunity	NA|268aa|down_9|NC_017186.1_2097626_2098430_+	pfam02517, Abi, CAAX protease self-immunity
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	9	2551218-2551314	8	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCTGCACCGCTGCGGTGATGGCCGGTGT	28	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA|447aa|down_2|NC_017186.1_2555243_2556584_-	NA|438aa|up_9|NC_017186.1_2539400_2540714_-	pfam03993, DUF349, Domain of Unknown Function (DUF349)	NA|304aa|up_8|NC_017186.1_2540932_2541844_+	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed	NA|276aa|up_7|NC_017186.1_2541854_2542682_+	PRK00450, dapF, diaminopimelate epimerase; Provisional	NA|838aa|up_6|NC_017186.1_2542698_2545212_-	NF000540, alt_ValS, valine--tRNA ligase	NA|418aa|up_5|NC_017186.1_2545221_2546475_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|168aa|up_4|NC_017186.1_2546538_2547042_+	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors	NA|483aa|up_3|NC_017186.1_2547084_2548533_+	COG2262, HflX, GTPases [General function prediction only]	NA|339aa|up_2|NC_017186.1_2548585_2549602_+	pfam13449, Phytase-like, Esterase-like activity of phytase	NA|220aa|up_1|NC_017186.1_2549675_2550335_-	PRK00215, PRK00215, transcriptional repressor LexA	NA|155aa|up_0|NC_017186.1_2550693_2551158_+	pfam01476, LysM, LysM domain	NA|165aa|down_0|NC_017186.1_2551836_2552331_+	PRK00464, nrdR, transcriptional repressor NrdR	NA|938aa|down_1|NC_017186.1_2552361_2555175_+	PRK06556, PRK06556, vitamin B12-dependent ribonucleotide reductase; Validated	NA|447aa|down_2|NC_017186.1_2555243_2556584_-	NA	NA|556aa|down_3|NC_017186.1_2556580_2558248_-	cd07302, CHD, cyclase homology domain	NA|249aa|down_4|NC_017186.1_2558409_2559156_+	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins	NA|210aa|down_5|NC_017186.1_2559170_2559800_+	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism]	NA|70aa|down_6|NC_017186.1_2559799_2560009_+	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]	NA|674aa|down_7|NC_017186.1_2559998_2562020_-	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]	NA|326aa|down_8|NC_017186.1_2562124_2563102_+	COG2321, COG2321, Predicted metalloprotease [General function prediction only]	NA|191aa|down_9|NC_017186.1_2563094_2563667_-	TIGR03086, TIGR03086, TIGR03086 family protein
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	10	2899104-2899190	9	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCCGGCCTGGCGAGCACTCTCCGGCCGG	29	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|394aa|up_7|NC_017186.1_2890882_2892064_+,NA|102aa|down_1|NC_017186.1_2899800_2900106_+,NA|139aa|down_8|NC_017186.1_2908431_2908848_-	NA|592aa|up_9|NC_017186.1_2888080_2889856_+	PRK00476, aspS, aspartyl-tRNA synthetase; Validated	NA|316aa|up_8|NC_017186.1_2889855_2890803_+	pfam04087, DUF389, Domain of unknown function (DUF389)	NA|394aa|up_7|NC_017186.1_2890882_2892064_+	NA	NA|289aa|up_6|NC_017186.1_2892444_2893311_+	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases	NA|243aa|up_5|NC_017186.1_2893282_2894011_-	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain	NA|403aa|up_4|NC_017186.1_2894073_2895282_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|232aa|up_3|NC_017186.1_2895312_2896008_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|459aa|up_2|NC_017186.1_2896150_2897527_+	PRK13342, PRK13342, recombination factor protein RarA; Reviewed	NA|126aa|up_1|NC_017186.1_2897672_2898050_+	pfam18029, Glyoxalase_6, Glyoxalase-like domain	NA|282aa|up_0|NC_017186.1_2898087_2898933_+	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]	NA|129aa|down_0|NC_017186.1_2899417_2899804_+	pfam06103, DUF948, Bacterial protein of unknown function (DUF948)	NA|102aa|down_1|NC_017186.1_2899800_2900106_+	NA	NA|887aa|down_2|NC_017186.1_2900178_2902839_+	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed	NA|167aa|down_3|NC_017186.1_2902831_2903332_+	pfam03652, RuvX, Holliday junction resolvase	NA|760aa|down_4|NC_017186.1_2903328_2905608_+	COG1559, COG1559, Aminodeoxychorismate lyase [Coenzyme transport and metabolism]	NA|285aa|down_5|NC_017186.1_2905597_2906452_+	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed	NA|427aa|down_6|NC_017186.1_2906515_2907796_+	pfam04229, GrpB, GrpB protein	NA|220aa|down_7|NC_017186.1_2907746_2908406_-	pfam17931, TetR_C_23, Tetracyclin repressor-like, C-terminal domain	NA|139aa|down_8|NC_017186.1_2908431_2908848_-	NA	NA|422aa|down_9|NC_017186.1_2908947_2910213_-	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	11	3229412-3229519	10	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCGATCCCCGTCCCGCCGGGCGTCG	26	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|163aa|up_9|NC_017186.1_3219590_3220079_-,NA|129aa|up_4|NC_017186.1_3224691_3225078_-,NA|97aa|down_2|NC_017186.1_3231015_3231306_+	NA|163aa|up_9|NC_017186.1_3219590_3220079_-	NA	NA|470aa|up_8|NC_017186.1_3220072_3221482_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|230aa|up_7|NC_017186.1_3221478_3222168_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|306aa|up_6|NC_017186.1_3222284_3223202_+	cd03396, PAP2_like_6, PAP2_like_6 proteins	NA|463aa|up_5|NC_017186.1_3223316_3224705_+	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]	NA|129aa|up_4|NC_017186.1_3224691_3225078_-	NA	NA|544aa|up_3|NC_017186.1_3225125_3226757_-	PRK08266, PRK08266, hypothetical protein; Provisional	NA|225aa|up_2|NC_017186.1_3226784_3227459_+	COG1802, GntR, Transcriptional regulators [Transcription]	NA|282aa|up_1|NC_017186.1_3227498_3228344_+	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|335aa|up_0|NC_017186.1_3228317_3229322_-	COG1741, COG1741, Pirin-related protein [General function prediction only]	NA|204aa|down_0|NC_017186.1_3229672_3230284_-	COG0704, PhoU, Phosphate uptake regulator [Inorganic ion transport and metabolism]	NA|145aa|down_1|NC_017186.1_3230409_3230844_+	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional	NA|97aa|down_2|NC_017186.1_3231015_3231306_+	NA	NA|131aa|down_3|NC_017186.1_3231623_3232016_-	pfam17032, zinc_ribbon_15, zinc-ribbon family	NA|142aa|down_4|NC_017186.1_3232183_3232609_+	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase	NA|705aa|down_5|NC_017186.1_3232610_3234725_-	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]	NA|274aa|down_6|NC_017186.1_3234761_3235583_-	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein	NA|147aa|down_7|NC_017186.1_3236344_3236785_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|108aa|down_8|NC_017186.1_3236856_3237180_-	pfam12840, HTH_20, Helix-turn-helix domain	NA|330aa|down_9|NC_017186.1_3237262_3238252_+	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	12	3575110-3575207	11	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GGACCGGATCGCTCCGGTCGAGG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|271aa|up_5|NC_017186.1_3565832_3566645_+,NA|146aa|up_4|NC_017186.1_3566648_3567086_-,NA|799aa|down_3|NC_017186.1_3577331_3579728_-	NA|615aa|up_9|NC_017186.1_3560893_3562738_+	pfam14200, RicinB_lectin_2, Ricin-type beta-trefoil lectin domain-like	NA|394aa|up_8|NC_017186.1_3562759_3563941_-	pfam09995, DUF2236, Uncharacterized protein conserved in bacteria (DUF2236)	NA|386aa|up_7|NC_017186.1_3564110_3565268_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|173aa|up_6|NC_017186.1_3565317_3565836_+	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|271aa|up_5|NC_017186.1_3565832_3566645_+	NA	NA|146aa|up_4|NC_017186.1_3566648_3567086_-	NA	NA|333aa|up_3|NC_017186.1_3567387_3568386_-	PRK07109, PRK07109, short chain dehydrogenase; Provisional	NA|598aa|up_2|NC_017186.1_3568741_3570535_-	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional	NA|159aa|up_1|NC_017186.1_3570660_3571137_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|416aa|up_0|NC_017186.1_3571241_3572489_-	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA)	NA|162aa|down_0|NC_017186.1_3575649_3576135_+	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only]	NA|127aa|down_1|NC_017186.1_3576131_3576512_+	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|255aa|down_2|NC_017186.1_3576525_3577290_+	COG3300, COG3300, MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]	NA|799aa|down_3|NC_017186.1_3577331_3579728_-	NA	NA|233aa|down_4|NC_017186.1_3580121_3580820_-	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|497aa|down_5|NC_017186.1_3580978_3582469_-	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin	NA|273aa|down_6|NC_017186.1_3582468_3583287_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|308aa|down_7|NC_017186.1_3583283_3584207_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|439aa|down_8|NC_017186.1_3584277_3585594_-	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold	NA|393aa|down_9|NC_017186.1_3585569_3586748_-	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	13	3580882-3580967	12	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	CCGGCTTGGGGCGAAGCCCCGGA	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|146aa|up_9|NC_017186.1_3566648_3567086_-,NA|799aa|up_1|NC_017186.1_3577331_3579728_-,NA	NA|146aa|up_9|NC_017186.1_3566648_3567086_-	NA	NA|333aa|up_8|NC_017186.1_3567387_3568386_-	PRK07109, PRK07109, short chain dehydrogenase; Provisional	NA|598aa|up_7|NC_017186.1_3568741_3570535_-	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional	NA|159aa|up_6|NC_017186.1_3570660_3571137_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|416aa|up_5|NC_017186.1_3571241_3572489_-	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA)	NA|162aa|up_4|NC_017186.1_3575649_3576135_+	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only]	NA|127aa|up_3|NC_017186.1_3576131_3576512_+	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|255aa|up_2|NC_017186.1_3576525_3577290_+	COG3300, COG3300, MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]	NA|799aa|up_1|NC_017186.1_3577331_3579728_-	NA	NA|233aa|up_0|NC_017186.1_3580121_3580820_-	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|497aa|down_0|NC_017186.1_3580978_3582469_-	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin	NA|273aa|down_1|NC_017186.1_3582468_3583287_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|308aa|down_2|NC_017186.1_3583283_3584207_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|439aa|down_3|NC_017186.1_3584277_3585594_-	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold	NA|393aa|down_4|NC_017186.1_3585569_3586748_-	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16	NA|316aa|down_5|NC_017186.1_3586884_3587832_-	cd01562, Thr-dehyd, Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen	NA|125aa|down_6|NC_017186.1_3587841_3588216_-	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|241aa|down_7|NC_017186.1_3588212_3588935_-	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family	NA|385aa|down_8|NC_017186.1_3589013_3590168_+	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|765aa|down_9|NC_017186.1_3590543_3592838_-	COG3903, COG3903, Predicted ATPase [General function prediction only]
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	14	3595321-3595412	13	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	TCACCAGCCTTTGTCGCTCATCG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA|47aa|down_3|NC_017186.1_3598810_3598951_+,NA|106aa|down_5|NC_017186.1_3600032_3600350_-	NA|308aa|up_9|NC_017186.1_3583283_3584207_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|439aa|up_8|NC_017186.1_3584277_3585594_-	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold	NA|393aa|up_7|NC_017186.1_3585569_3586748_-	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16	NA|316aa|up_6|NC_017186.1_3586884_3587832_-	cd01562, Thr-dehyd, Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen	NA|125aa|up_5|NC_017186.1_3587841_3588216_-	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|241aa|up_4|NC_017186.1_3588212_3588935_-	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family	NA|385aa|up_3|NC_017186.1_3589013_3590168_+	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|765aa|up_2|NC_017186.1_3590543_3592838_-	COG3903, COG3903, Predicted ATPase [General function prediction only]	NA|184aa|up_1|NC_017186.1_3593173_3593725_-	pfam09990, DUF2231, Predicted membrane protein (DUF2231)	NA|405aa|up_0|NC_017186.1_3594101_3595316_+	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|397aa|down_0|NC_017186.1_3595652_3596843_+	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|332aa|down_1|NC_017186.1_3596854_3597850_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|281aa|down_2|NC_017186.1_3597932_3598775_+	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH)	NA|47aa|down_3|NC_017186.1_3598810_3598951_+	NA	NA|251aa|down_4|NC_017186.1_3599299_3600052_+	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]	NA|106aa|down_5|NC_017186.1_3600032_3600350_-	NA	NA|200aa|down_6|NC_017186.1_3600376_3600976_-	cd08862, SRPBCC_Smu440-like, Ligand-binding SRPBCC domain of Streptococcus mutans Smu	NA|213aa|down_7|NC_017186.1_3601069_3601708_+	pfam13305, WHG, WHG domain	NA|277aa|down_8|NC_017186.1_3601709_3602540_-	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms	NA|214aa|down_9|NC_017186.1_3602651_3603293_-	COG1309, AcrR, Transcriptional regulator [Transcription]
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	15	5355889-5356032	14	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCCGCAACACCGGAAGCGGCGG	23	0	0	NA	NA	NA	2	2	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA|53aa|down_0|NC_017186.1_5357967_5358126_-,NA|150aa|down_1|NC_017186.1_5358122_5358572_-,NA|274aa|down_9|NC_017186.1_5368207_5369029_-	NA|217aa|up_9|NC_017186.1_5340783_5341434_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|209aa|up_8|NC_017186.1_5341539_5342166_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|445aa|up_7|NC_017186.1_5342172_5343507_-	COG1470, COG1470, Predicted membrane protein [Function unknown]	NA|1343aa|up_6|NC_017186.1_5343670_5347699_-	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB	NA|180aa|up_5|NC_017186.1_5348732_5349272_-	TIGR02242, putative_secreted_protein, phage tail protein domain	NA|145aa|up_4|NC_017186.1_5351230_5351665_-	pfam04965, GPW_gp25, Gene 25-like lysozyme	NA|94aa|up_3|NC_017186.1_5351672_5351954_-	cd14739, PAAR_3, proline-alanine-alanine-arginine (PAAR) domain	NA|608aa|up_2|NC_017186.1_5351966_5353790_-	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein	NA|254aa|up_1|NC_017186.1_5353782_5354544_-	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan	NA|149aa|up_0|NC_017186.1_5354547_5354994_-	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19	NA|53aa|down_0|NC_017186.1_5357967_5358126_-	NA	NA|150aa|down_1|NC_017186.1_5358122_5358572_-	NA	NA|148aa|down_2|NC_017186.1_5358576_5359020_-	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19	NA|518aa|down_3|NC_017186.1_5359091_5360645_-	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only]	NA|1115aa|down_4|NC_017186.1_5360926_5364271_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|248aa|down_5|NC_017186.1_5364304_5365048_-	pfam13699, DUF4157, Domain of unknown function (DUF4157)	NA|662aa|down_6|NC_017186.1_5365151_5367137_-	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]	NA|220aa|down_7|NC_017186.1_5367133_5367793_-	pfam14065, DUF4255, Protein of unknown function (DUF4255)	NA|104aa|down_8|NC_017186.1_5367981_5368293_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|274aa|down_9|NC_017186.1_5368207_5369029_-	NA
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	16	5356387-5356467	15	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCCGCAACACCGGAAGCGGCGG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA|53aa|down_0|NC_017186.1_5357967_5358126_-,NA|150aa|down_1|NC_017186.1_5358122_5358572_-,NA|274aa|down_9|NC_017186.1_5368207_5369029_-	NA|217aa|up_9|NC_017186.1_5340783_5341434_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|209aa|up_8|NC_017186.1_5341539_5342166_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|445aa|up_7|NC_017186.1_5342172_5343507_-	COG1470, COG1470, Predicted membrane protein [Function unknown]	NA|1343aa|up_6|NC_017186.1_5343670_5347699_-	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB	NA|180aa|up_5|NC_017186.1_5348732_5349272_-	TIGR02242, putative_secreted_protein, phage tail protein domain	NA|145aa|up_4|NC_017186.1_5351230_5351665_-	pfam04965, GPW_gp25, Gene 25-like lysozyme	NA|94aa|up_3|NC_017186.1_5351672_5351954_-	cd14739, PAAR_3, proline-alanine-alanine-arginine (PAAR) domain	NA|608aa|up_2|NC_017186.1_5351966_5353790_-	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein	NA|254aa|up_1|NC_017186.1_5353782_5354544_-	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan	NA|149aa|up_0|NC_017186.1_5354547_5354994_-	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19	NA|53aa|down_0|NC_017186.1_5357967_5358126_-	NA	NA|150aa|down_1|NC_017186.1_5358122_5358572_-	NA	NA|148aa|down_2|NC_017186.1_5358576_5359020_-	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19	NA|518aa|down_3|NC_017186.1_5359091_5360645_-	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only]	NA|1115aa|down_4|NC_017186.1_5360926_5364271_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|248aa|down_5|NC_017186.1_5364304_5365048_-	pfam13699, DUF4157, Domain of unknown function (DUF4157)	NA|662aa|down_6|NC_017186.1_5365151_5367137_-	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]	NA|220aa|down_7|NC_017186.1_5367133_5367793_-	pfam14065, DUF4255, Protein of unknown function (DUF4255)	NA|104aa|down_8|NC_017186.1_5367981_5368293_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|274aa|down_9|NC_017186.1_5368207_5369029_-	NA
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	17	5356741-5356829	16	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCCGCAACACCGGAAGCGGCGG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA|53aa|down_0|NC_017186.1_5357967_5358126_-,NA|150aa|down_1|NC_017186.1_5358122_5358572_-,NA|274aa|down_9|NC_017186.1_5368207_5369029_-	NA|217aa|up_9|NC_017186.1_5340783_5341434_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|209aa|up_8|NC_017186.1_5341539_5342166_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|445aa|up_7|NC_017186.1_5342172_5343507_-	COG1470, COG1470, Predicted membrane protein [Function unknown]	NA|1343aa|up_6|NC_017186.1_5343670_5347699_-	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB	NA|180aa|up_5|NC_017186.1_5348732_5349272_-	TIGR02242, putative_secreted_protein, phage tail protein domain	NA|145aa|up_4|NC_017186.1_5351230_5351665_-	pfam04965, GPW_gp25, Gene 25-like lysozyme	NA|94aa|up_3|NC_017186.1_5351672_5351954_-	cd14739, PAAR_3, proline-alanine-alanine-arginine (PAAR) domain	NA|608aa|up_2|NC_017186.1_5351966_5353790_-	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein	NA|254aa|up_1|NC_017186.1_5353782_5354544_-	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan	NA|149aa|up_0|NC_017186.1_5354547_5354994_-	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19	NA|53aa|down_0|NC_017186.1_5357967_5358126_-	NA	NA|150aa|down_1|NC_017186.1_5358122_5358572_-	NA	NA|148aa|down_2|NC_017186.1_5358576_5359020_-	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19	NA|518aa|down_3|NC_017186.1_5359091_5360645_-	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only]	NA|1115aa|down_4|NC_017186.1_5360926_5364271_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|248aa|down_5|NC_017186.1_5364304_5365048_-	pfam13699, DUF4157, Domain of unknown function (DUF4157)	NA|662aa|down_6|NC_017186.1_5365151_5367137_-	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]	NA|220aa|down_7|NC_017186.1_5367133_5367793_-	pfam14065, DUF4255, Protein of unknown function (DUF4255)	NA|104aa|down_8|NC_017186.1_5367981_5368293_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|274aa|down_9|NC_017186.1_5368207_5369029_-	NA
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	18	5780710-5780792	17	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	CGGGGCGGAGCCCCGGTTGTCAC	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|66aa|up_4|NC_017186.1_5777635_5777833_-,NA|71aa|up_3|NC_017186.1_5778012_5778225_+,NA|110aa|down_0|NC_017186.1_5780894_5781224_+,NA|158aa|down_6|NC_017186.1_5785639_5786113_-	NA|139aa|up_9|NC_017186.1_5773734_5774151_-	cd04622, CBS_pair_HRP1_like, CBS pair domain found in Hypoxic Response Protein 1 (HRP1) -like proteinds	NA|211aa|up_8|NC_017186.1_5774242_5774875_+	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain	NA|288aa|up_7|NC_017186.1_5774885_5775749_-	cd04861, LigD_Pol_like, LigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD	NA|315aa|up_6|NC_017186.1_5775745_5776690_-	PRK05972, ligD, ATP-dependent DNA ligase; Reviewed	NA|311aa|up_5|NC_017186.1_5776686_5777619_-	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku	NA|66aa|up_4|NC_017186.1_5777635_5777833_-	NA	NA|71aa|up_3|NC_017186.1_5778012_5778225_+	NA	NA|243aa|up_2|NC_017186.1_5778267_5778996_-	pfam03861, ANTAR, ANTAR domain	NA|122aa|up_1|NC_017186.1_5779289_5779655_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|322aa|up_0|NC_017186.1_5779685_5780651_-	TIGR03557, F420_G6P_family, F420-dependent oxidoreductase, G6PDH family	NA|110aa|down_0|NC_017186.1_5780894_5781224_+	NA	NA|150aa|down_1|NC_017186.1_5781286_5781736_+	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional	NA|264aa|down_2|NC_017186.1_5781732_5782524_+	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed	NA|506aa|down_3|NC_017186.1_5782555_5784073_-	smart00880, CHAD, The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family	NA|174aa|down_4|NC_017186.1_5784197_5784719_+	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain	NA|267aa|down_5|NC_017186.1_5784760_5785561_+	pfam03861, ANTAR, ANTAR domain	NA|158aa|down_6|NC_017186.1_5785639_5786113_-	NA	NA|155aa|down_7|NC_017186.1_5786277_5786742_-	cd07817, SRPBCC_8, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|138aa|down_8|NC_017186.1_5786877_5787291_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|102aa|down_9|NC_017186.1_5787287_5787593_+	pfam12277, DUF3618, Protein of unknown function (DUF3618)
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	19	6436780-6437778	18,3,2	CRISPRCasFinder,CRT,PILER-CR	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Type I-E	GTTGTCCCCGCACGCGCGGGGCTGGTCCC,TCCCCGCGCACGCGGGGCTGGTCC,CGCACGCGGGGCTGGTCC	29,24,18	0	0	NA	NA	NA:NA:NA	16,16,4	16	TypeI-E	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|163aa|up_9|NC_017186.1_6421783_6422272_+,NA|187aa|up_8|NC_017186.1_6423308_6423869_+,NA|217aa|up_7|NC_017186.1_6423865_6424516_+,NA|378aa|up_6|NC_017186.1_6424512_6425646_+,NA|142aa|up_5|NC_017186.1_6425600_6426026_-,NA|185aa|up_4|NC_017186.1_6426349_6426904_-,NA|202aa|up_2|NC_017186.1_6427890_6428496_-,NA|82aa|down_2|NC_017186.1_6443991_6444237_+	NA|163aa|up_9|NC_017186.1_6421783_6422272_+	NA	NA|187aa|up_8|NC_017186.1_6423308_6423869_+	NA	NA|217aa|up_7|NC_017186.1_6423865_6424516_+	NA	NA|378aa|up_6|NC_017186.1_6424512_6425646_+	NA	NA|142aa|up_5|NC_017186.1_6425600_6426026_-	NA	NA|185aa|up_4|NC_017186.1_6426349_6426904_-	NA	NA|278aa|up_3|NC_017186.1_6426959_6427792_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|202aa|up_2|NC_017186.1_6427890_6428496_-	NA	NA|398aa|up_1|NC_017186.1_6428988_6430182_+	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies)	NA|1729aa|up_0|NC_017186.1_6430525_6435712_-	pfam13020, DUF3883, Domain of unknown function (DUF3883)	NA|128aa|down_0|NC_017186.1_6437865_6438249_+	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family	NA|344aa|down_1|NC_017186.1_6442309_6443341_+	pfam04471, Mrr_cat, Restriction endonuclease	NA|82aa|down_2|NC_017186.1_6443991_6444237_+	NA	cas6e|217aa|down_3|NC_017186.1_6444968_6445619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|237aa|down_4|NC_017186.1_6445609_6446320_-	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas7|377aa|down_5|NC_017186.1_6446316_6447447_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|199aa|down_6|NC_017186.1_6447443_6448040_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|527aa|down_7|NC_017186.1_6448036_6449617_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	NA|107aa|down_8|NC_017186.1_6449613_6449934_-	pfam18395, Cas3_C, Cas3 C-terminal domain	cas3|760aa|down_9|NC_017186.1_6449930_6452210_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	20	6438603-6438875	3,19,4	PILER-CR,CRISPRCasFinder,CRT	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Type I-E	GTTGTCCCCGCACGCGCGGGGCTGGTCC,GTTGTCCCCGCACGCGCGGGGCTGGTCCC,GTTGTCCCCGCACGCGCGGGGCTGGTCC	28,29,28	0	0	NA	NA	NA:NA:NA	3,4,4	4	TypeI-E	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|187aa|up_9|NC_017186.1_6423308_6423869_+,NA|217aa|up_8|NC_017186.1_6423865_6424516_+,NA|378aa|up_7|NC_017186.1_6424512_6425646_+,NA|142aa|up_6|NC_017186.1_6425600_6426026_-,NA|185aa|up_5|NC_017186.1_6426349_6426904_-,NA|202aa|up_3|NC_017186.1_6427890_6428496_-,NA|82aa|down_1|NC_017186.1_6443991_6444237_+	NA|187aa|up_9|NC_017186.1_6423308_6423869_+	NA	NA|217aa|up_8|NC_017186.1_6423865_6424516_+	NA	NA|378aa|up_7|NC_017186.1_6424512_6425646_+	NA	NA|142aa|up_6|NC_017186.1_6425600_6426026_-	NA	NA|185aa|up_5|NC_017186.1_6426349_6426904_-	NA	NA|278aa|up_4|NC_017186.1_6426959_6427792_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|202aa|up_3|NC_017186.1_6427890_6428496_-	NA	NA|398aa|up_2|NC_017186.1_6428988_6430182_+	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies)	NA|1729aa|up_1|NC_017186.1_6430525_6435712_-	pfam13020, DUF3883, Domain of unknown function (DUF3883)	NA|128aa|up_0|NC_017186.1_6437865_6438249_+	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family	NA|344aa|down_0|NC_017186.1_6442309_6443341_+	pfam04471, Mrr_cat, Restriction endonuclease	NA|82aa|down_1|NC_017186.1_6443991_6444237_+	NA	cas6e|217aa|down_2|NC_017186.1_6444968_6445619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|237aa|down_3|NC_017186.1_6445609_6446320_-	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas7|377aa|down_4|NC_017186.1_6446316_6447447_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|199aa|down_5|NC_017186.1_6447443_6448040_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|527aa|down_6|NC_017186.1_6448036_6449617_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	NA|107aa|down_7|NC_017186.1_6449613_6449934_-	pfam18395, Cas3_C, Cas3 C-terminal domain	cas3|760aa|down_8|NC_017186.1_6449930_6452210_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|277aa|down_9|NC_017186.1_6453003_6453834_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	21	6441416-6441811	20,5	CRISPRCasFinder,CRT	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Type I-E	GTTGTCCCCGCACGCGCGGGGCTGGTCCC,GTCGTCCCCGCGTACGCGGGGCTGGTCC	29,28	0	0	NA	NA	NA:NA	6,6	6	TypeI-E	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|187aa|up_9|NC_017186.1_6423308_6423869_+,NA|217aa|up_8|NC_017186.1_6423865_6424516_+,NA|378aa|up_7|NC_017186.1_6424512_6425646_+,NA|142aa|up_6|NC_017186.1_6425600_6426026_-,NA|185aa|up_5|NC_017186.1_6426349_6426904_-,NA|202aa|up_3|NC_017186.1_6427890_6428496_-,NA|82aa|down_1|NC_017186.1_6443991_6444237_+	NA|187aa|up_9|NC_017186.1_6423308_6423869_+	NA	NA|217aa|up_8|NC_017186.1_6423865_6424516_+	NA	NA|378aa|up_7|NC_017186.1_6424512_6425646_+	NA	NA|142aa|up_6|NC_017186.1_6425600_6426026_-	NA	NA|185aa|up_5|NC_017186.1_6426349_6426904_-	NA	NA|278aa|up_4|NC_017186.1_6426959_6427792_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|202aa|up_3|NC_017186.1_6427890_6428496_-	NA	NA|398aa|up_2|NC_017186.1_6428988_6430182_+	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies)	NA|1729aa|up_1|NC_017186.1_6430525_6435712_-	pfam13020, DUF3883, Domain of unknown function (DUF3883)	NA|128aa|up_0|NC_017186.1_6437865_6438249_+	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family	NA|344aa|down_0|NC_017186.1_6442309_6443341_+	pfam04471, Mrr_cat, Restriction endonuclease	NA|82aa|down_1|NC_017186.1_6443991_6444237_+	NA	cas6e|217aa|down_2|NC_017186.1_6444968_6445619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|237aa|down_3|NC_017186.1_6445609_6446320_-	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas7|377aa|down_4|NC_017186.1_6446316_6447447_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|199aa|down_5|NC_017186.1_6447443_6448040_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|527aa|down_6|NC_017186.1_6448036_6449617_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	NA|107aa|down_7|NC_017186.1_6449613_6449934_-	pfam18395, Cas3_C, Cas3 C-terminal domain	cas3|760aa|down_8|NC_017186.1_6449930_6452210_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|277aa|down_9|NC_017186.1_6453003_6453834_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	22	6441951-6442222	21	CRISPRCasFinder	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Type I-E	GTTGTCCCCGCACGCGCGGGGCTGGTCCC	29	0	0	NA	NA	NA	4	4	TypeI-E	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|187aa|up_9|NC_017186.1_6423308_6423869_+,NA|217aa|up_8|NC_017186.1_6423865_6424516_+,NA|378aa|up_7|NC_017186.1_6424512_6425646_+,NA|142aa|up_6|NC_017186.1_6425600_6426026_-,NA|185aa|up_5|NC_017186.1_6426349_6426904_-,NA|202aa|up_3|NC_017186.1_6427890_6428496_-,NA|82aa|down_1|NC_017186.1_6443991_6444237_+	NA|187aa|up_9|NC_017186.1_6423308_6423869_+	NA	NA|217aa|up_8|NC_017186.1_6423865_6424516_+	NA	NA|378aa|up_7|NC_017186.1_6424512_6425646_+	NA	NA|142aa|up_6|NC_017186.1_6425600_6426026_-	NA	NA|185aa|up_5|NC_017186.1_6426349_6426904_-	NA	NA|278aa|up_4|NC_017186.1_6426959_6427792_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|202aa|up_3|NC_017186.1_6427890_6428496_-	NA	NA|398aa|up_2|NC_017186.1_6428988_6430182_+	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies)	NA|1729aa|up_1|NC_017186.1_6430525_6435712_-	pfam13020, DUF3883, Domain of unknown function (DUF3883)	NA|128aa|up_0|NC_017186.1_6437865_6438249_+	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family	NA|344aa|down_0|NC_017186.1_6442309_6443341_+	pfam04471, Mrr_cat, Restriction endonuclease	NA|82aa|down_1|NC_017186.1_6443991_6444237_+	NA	cas6e|217aa|down_2|NC_017186.1_6444968_6445619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|237aa|down_3|NC_017186.1_6445609_6446320_-	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas7|377aa|down_4|NC_017186.1_6446316_6447447_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|199aa|down_5|NC_017186.1_6447443_6448040_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|527aa|down_6|NC_017186.1_6448036_6449617_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	NA|107aa|down_7|NC_017186.1_6449613_6449934_-	pfam18395, Cas3_C, Cas3 C-terminal domain	cas3|760aa|down_8|NC_017186.1_6449930_6452210_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|277aa|down_9|NC_017186.1_6453003_6453834_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	23	6444434-6444702	22	CRISPRCasFinder	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Type I-E	GTCGTCCCCTCGCAAGCGGGGCTG	24	0	0	NA	NA	NA	4	4	TypeI-E	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|378aa|up_9|NC_017186.1_6424512_6425646_+,NA|142aa|up_8|NC_017186.1_6425600_6426026_-,NA|185aa|up_7|NC_017186.1_6426349_6426904_-,NA|202aa|up_5|NC_017186.1_6427890_6428496_-,NA|82aa|up_0|NC_017186.1_6443991_6444237_+,NA|619aa|down_9|NC_017186.1_6454593_6456450_-	NA|378aa|up_9|NC_017186.1_6424512_6425646_+	NA	NA|142aa|up_8|NC_017186.1_6425600_6426026_-	NA	NA|185aa|up_7|NC_017186.1_6426349_6426904_-	NA	NA|278aa|up_6|NC_017186.1_6426959_6427792_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|202aa|up_5|NC_017186.1_6427890_6428496_-	NA	NA|398aa|up_4|NC_017186.1_6428988_6430182_+	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies)	NA|1729aa|up_3|NC_017186.1_6430525_6435712_-	pfam13020, DUF3883, Domain of unknown function (DUF3883)	NA|128aa|up_2|NC_017186.1_6437865_6438249_+	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family	NA|344aa|up_1|NC_017186.1_6442309_6443341_+	pfam04471, Mrr_cat, Restriction endonuclease	NA|82aa|up_0|NC_017186.1_6443991_6444237_+	NA	cas6e|217aa|down_0|NC_017186.1_6444968_6445619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|237aa|down_1|NC_017186.1_6445609_6446320_-	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas7|377aa|down_2|NC_017186.1_6446316_6447447_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|199aa|down_3|NC_017186.1_6447443_6448040_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|527aa|down_4|NC_017186.1_6448036_6449617_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	NA|107aa|down_5|NC_017186.1_6449613_6449934_-	pfam18395, Cas3_C, Cas3 C-terminal domain	cas3|760aa|down_6|NC_017186.1_6449930_6452210_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|277aa|down_7|NC_017186.1_6453003_6453834_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|108aa|down_8|NC_017186.1_6453920_6454244_-	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|619aa|down_9|NC_017186.1_6454593_6456450_-	NA
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	24	6444797-6444943	23	CRISPRCasFinder	no	cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Type I-E	GTCGTCCCCTCGCAAGCGGGGCTG	24	0	0	NA	NA	NA	2	2	TypeI-E	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|378aa|up_9|NC_017186.1_6424512_6425646_+,NA|142aa|up_8|NC_017186.1_6425600_6426026_-,NA|185aa|up_7|NC_017186.1_6426349_6426904_-,NA|202aa|up_5|NC_017186.1_6427890_6428496_-,NA|82aa|up_0|NC_017186.1_6443991_6444237_+,NA|619aa|down_9|NC_017186.1_6454593_6456450_-	NA|378aa|up_9|NC_017186.1_6424512_6425646_+	NA	NA|142aa|up_8|NC_017186.1_6425600_6426026_-	NA	NA|185aa|up_7|NC_017186.1_6426349_6426904_-	NA	NA|278aa|up_6|NC_017186.1_6426959_6427792_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|202aa|up_5|NC_017186.1_6427890_6428496_-	NA	NA|398aa|up_4|NC_017186.1_6428988_6430182_+	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies)	NA|1729aa|up_3|NC_017186.1_6430525_6435712_-	pfam13020, DUF3883, Domain of unknown function (DUF3883)	NA|128aa|up_2|NC_017186.1_6437865_6438249_+	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family	NA|344aa|up_1|NC_017186.1_6442309_6443341_+	pfam04471, Mrr_cat, Restriction endonuclease	NA|82aa|up_0|NC_017186.1_6443991_6444237_+	NA	cas6e|217aa|down_0|NC_017186.1_6444968_6445619_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|237aa|down_1|NC_017186.1_6445609_6446320_-	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas7|377aa|down_2|NC_017186.1_6446316_6447447_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|199aa|down_3|NC_017186.1_6447443_6448040_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|527aa|down_4|NC_017186.1_6448036_6449617_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	NA|107aa|down_5|NC_017186.1_6449613_6449934_-	pfam18395, Cas3_C, Cas3 C-terminal domain	cas3|760aa|down_6|NC_017186.1_6449930_6452210_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|277aa|down_7|NC_017186.1_6453003_6453834_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|108aa|down_8|NC_017186.1_6453920_6454244_-	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|619aa|down_9|NC_017186.1_6454593_6456450_-	NA
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	25	6960989-6961083	24	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	CTCCGCCACCCGAACCCCCGAAAAGCGGCTGTG	33	1	36	6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050|6961022-6961050	NC_017186.1_2183135-2183107|NC_017186.1_557412-557440|NC_017186.1_2916209-2916237|NC_017186.1_5989687-5989715|NC_017186.1_6196696-6196724|NC_017186.1_8163985-8164013|NC_017186.1_71575-71547|NC_017186.1_247695-247667|NC_017186.1_247755-247727|NC_017186.1_247816-247788|NC_017186.1_1133612-1133584|NC_017186.1_3315721-3315693|NC_017186.1_3320068-3320040|NC_017186.1_3377325-3377297|NC_017186.1_7397426-7397398|NC_017186.1_9965563-9965535|NC_017186.1_557286-557314|NC_017186.1_557349-557377|NC_017186.1_580730-580758|NC_017186.1_824870-824898|NC_017186.1_1455611-1455639|NC_017186.1_7434897-7434925|NC_017186.1_7627943-7627971|NC_017186.1_8429222-8429250|NC_017186.1_8927885-8927913|NC_017186.1_10032795-10032823|NC_017186.1_1842512-1842484|NC_017186.1_2167312-2167284|NC_017186.1_2497861-2497833|NC_017186.1_2613957-2613929|NC_017186.1_2817088-2817060|NC_017186.1_3537749-3537721|NC_017186.1_5078224-5078196|NC_017186.1_5780729-5780701|NC_017186.1_7298562-7298534|NC_017186.1_8652700-8652672	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA,NA|104aa|down_3|NC_017186.1_6962812_6963124_-,NA|181aa|down_9|NC_017186.1_6969384_6969927_-	NA|349aa|up_9|NC_017186.1_6950760_6951807_+	PRK09358, PRK09358, adenosine deaminase; Provisional	NA|187aa|up_8|NC_017186.1_6952173_6952734_+	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]	NA|346aa|up_7|NC_017186.1_6952799_6953837_+	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase	NA|470aa|up_6|NC_017186.1_6953808_6955218_-	PRK08186, PRK08186, allophanate hydrolase; Provisional	NA|329aa|up_5|NC_017186.1_6955727_6956714_-	PRK01209, cobD, cobalamin biosynthesis protein	NA|280aa|up_4|NC_017186.1_6956737_6957577_-	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]	NA|153aa|up_3|NC_017186.1_6957805_6958264_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|154aa|up_2|NC_017186.1_6958363_6958825_-	pfam02464, CinA, Competence-damaged protein	NA|214aa|up_1|NC_017186.1_6958827_6959469_-	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA|479aa|up_0|NC_017186.1_6959465_6960902_-	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO	NA|170aa|down_0|NC_017186.1_6961122_6961632_+	PRK07922, PRK07922, amino-acid N-acetyltransferase	NA|145aa|down_1|NC_017186.1_6961723_6962158_+	pfam09056, Phospholip_A2_3, Prokaryotic phospholipase A2	NA|204aa|down_2|NC_017186.1_6962208_6962820_+	pfam00881, Nitroreductase, Nitroreductase family	NA|104aa|down_3|NC_017186.1_6962812_6963124_-	NA	NA|169aa|down_4|NC_017186.1_6963293_6963800_-	pfam13707, RloB, RloB-like protein	NA|406aa|down_5|NC_017186.1_6963865_6965083_-	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system	NA|830aa|down_6|NC_017186.1_6965164_6967654_-	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]	NA|276aa|down_7|NC_017186.1_6967870_6968698_+	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like	NA|205aa|down_8|NC_017186.1_6968731_6969346_+	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|181aa|down_9|NC_017186.1_6969384_6969927_-	NA
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	26	8279767-8280303	6	CRT	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCTCGGCTCGGCNCGGCCCGGCNCGGC	27	5	16	8280011-8280029|8280011-8280029|8280011-8280029|8280011-8280029|8280108-8280141|8280108-8280141|8280108-8280141|8280169-8280186|8280214-8280231|8280214-8280231|8280214-8280231|8280214-8280231|8280259-8280276|8280259-8280276|8280259-8280276|8280259-8280276	NC_017186.1_2047151-2047133|NC_017186.1_4313881-4313863|NC_017186.1_5071229-5071247|NC_017186.1_7612726-7612744|NC_017186.1_8280273-8280306|NC_017186.1_8280278-8280311|NC_017186.1_8280283-8280316|NC_017186.1_5200267-5200284|NC_017186.1_8280289-8280306|NC_017186.1_8280294-8280311|NC_017186.1_8280299-8280316|NC_017186.1_8307405-8307422|NC_017186.1_8280289-8280306|NC_017186.1_8280294-8280311|NC_017186.1_8280299-8280316|NC_017186.1_8307405-8307422	NA	9	9	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|62aa|up_3|NC_017186.1_8276763_8276949_+,NA	NA|585aa|up_9|NC_017186.1_8268485_8270240_-	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35	NA|515aa|up_8|NC_017186.1_8270232_8271777_-	COG3534, AbfA, Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]	NA|447aa|up_7|NC_017186.1_8271773_8273114_-	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|288aa|up_6|NC_017186.1_8273163_8274027_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|309aa|up_5|NC_017186.1_8274028_8274955_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|352aa|up_4|NC_017186.1_8275066_8276122_+	cd01574, PBP1_LacI, ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators	NA|62aa|up_3|NC_017186.1_8276763_8276949_+	NA	NA|213aa|up_2|NC_017186.1_8276923_8277562_-	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif	NA|200aa|up_1|NC_017186.1_8277784_8278384_+	pfam18598, TetR_C_36, Tetracyclin repressor-like, C-terminal domain	NA|310aa|up_0|NC_017186.1_8278581_8279511_+	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only]	NA|327aa|down_0|NC_017186.1_8280453_8281434_-	cd08267, MDR1, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|220aa|down_1|NC_017186.1_8281533_8282193_+	PRK13756, PRK13756, TetR family transcriptional regulator	NA|341aa|down_2|NC_017186.1_8282214_8283237_+	TIGR04027, Luciferase-like_monooxygenase, putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family	NA|225aa|down_3|NC_017186.1_8283238_8283913_-	pfam02469, Fasciclin, Fasciclin domain	NA|508aa|down_4|NC_017186.1_8284006_8285530_-	cd02110, SO_family_Moco_dimer, Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain	NA|227aa|down_5|NC_017186.1_8285522_8286203_-	pfam10099, RskA, Anti-sigma-K factor rskA	NA|191aa|down_6|NC_017186.1_8286199_8286772_-	PRK09646, PRK09646, ECF RNA polymerase sigma factor SigK	NA|138aa|down_7|NC_017186.1_8287130_8287544_+	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA	NA|455aa|down_8|NC_017186.1_8287559_8288924_+	cd04433, AFD_class_I, Adenylate forming domain, Class I, also known as the ANL superfamily	NA|564aa|down_9|NC_017186.1_8288913_8290605_-	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional
GCF_000220945.1_ASM22094v1	NC_017186	Amycolatopsis mediterranei S699, complete sequence	27	10142210-10142316	25	CRISPRCasFinder	no		DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	Orphan	GCCCCCGCCCGGCGGCCGCCGTCC	24	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,WYL,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	NA|233aa|up_4|NC_017186.1_10138253_10138952_-,NA|301aa|down_7|NC_017186.1_10153790_10154693_+	NA|540aa|up_9|NC_017186.1_10131973_10133593_-	pfam17210, SdrD_B, SdrD B-like domain	NA|689aa|up_8|NC_017186.1_10133715_10135782_-	pfam05787, DUF839, Bacterial protein of unknown function (DUF839)	NA|406aa|up_7|NC_017186.1_10135890_10137108_-	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily	NA|153aa|up_6|NC_017186.1_10137097_10137556_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|213aa|up_5|NC_017186.1_10137622_10138261_+	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only]	NA|233aa|up_4|NC_017186.1_10138253_10138952_-	NA	NA|173aa|up_3|NC_017186.1_10138948_10139467_-	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|363aa|up_2|NC_017186.1_10139570_10140659_-	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type	NA|182aa|up_1|NC_017186.1_10140731_10141277_-	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|132aa|up_0|NC_017186.1_10141521_10141917_+	pfam17249, DUF5318, Family of unknown function (DUF5318)	NA|785aa|down_0|NC_017186.1_10144784_10147139_+	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]	NA|349aa|down_1|NC_017186.1_10147214_10148261_-	PRK11579, PRK11579, putative oxidoreductase; Provisional	NA|353aa|down_2|NC_017186.1_10148316_10149375_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|517aa|down_3|NC_017186.1_10149423_10150974_+	COG5650, COG5650, Predicted integral membrane protein [Function unknown]	NA|258aa|down_4|NC_017186.1_10150984_10151758_-	PRK01060, PRK01060, endonuclease IV; Provisional	NA|271aa|down_5|NC_017186.1_10151869_10152682_+	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|302aa|down_6|NC_017186.1_10152799_10153705_+	PRK09010, PRK09010, single-stranded DNA-binding protein; Provisional	NA|301aa|down_7|NC_017186.1_10153790_10154693_+	NA	NA|109aa|down_8|NC_017186.1_10154809_10155136_+	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed	NA|172aa|down_9|NC_017186.1_10155153_10155669_+	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional
