assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000177195.2_ASM17719v2	NC_015953	Streptomyces sp. SirexAA-E, complete sequence	1	1401276-1401391	1	CRISPRCasFinder	no	DEDDh	WYL,DEDDh,cas4,csa3,cas3,DinG	Unclear	CTCAACACGACGCAGGAGGGCGGGCGATGA	30	0	0	NA	NA	NA	1	1	Orphan	WYL,DEDDh,cas4,csa3,cas3,DinG	NA|70aa|up_5|NC_015953.1_1394888_1395098_-,NA|123aa|up_2|NC_015953.1_1397486_1397855_-,NA|83aa|down_3|NC_015953.1_1405269_1405518_+	NA|249aa|up_9|NC_015953.1_1389182_1389929_+	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains	NA|849aa|up_8|NC_015953.1_1390077_1392624_-	cd03213, ABCG_EPDR, Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily	NA|419aa|up_7|NC_015953.1_1392950_1394207_+	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p	NA|175aa|up_6|NC_015953.1_1394277_1394802_-	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms]	NA|70aa|up_5|NC_015953.1_1394888_1395098_-	NA	NA|429aa|up_4|NC_015953.1_1395383_1396670_-	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters	NA|225aa|up_3|NC_015953.1_1396800_1397475_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|123aa|up_2|NC_015953.1_1397486_1397855_-	NA	NA|256aa|up_1|NC_015953.1_1398036_1398804_-	PRK07889, PRK07889, enoyl-[acyl-carrier-protein] reductase FabI	NA|240aa|up_0|NC_015953.1_1398809_1399529_-	TIGR01830, 3-oxoacyl-_reductase_FabG, 3-oxoacyl-(acyl-carrier-protein) reductase	NA|423aa|down_0|NC_015953.1_1402835_1404104_+	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated	NA|95aa|down_1|NC_015953.1_1404183_1404468_-	PRK10457, PRK10457, hypothetical protein; Provisional	NA|136aa|down_2|NC_015953.1_1404644_1405052_+	pfam11298, DUF3099, Protein of unknown function (DUF3099)	NA|83aa|down_3|NC_015953.1_1405269_1405518_+	NA	NA|337aa|down_4|NC_015953.1_1405500_1406511_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|545aa|down_5|NC_015953.1_1406640_1408275_-	cd11480, SLC5sbd_u4, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain	NA|122aa|down_6|NC_015953.1_1408271_1408637_-	pfam04341, DUF485, Protein of unknown function, DUF485	NA|510aa|down_7|NC_015953.1_1408944_1410474_+	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins	NA|228aa|down_8|NC_015953.1_1410531_1411215_-	pfam07947, YhhN, YhhN family	NA|301aa|down_9|NC_015953.1_1411211_1412114_-	COG3000, ERG3, Sterol desaturase [Lipid metabolism]
GCF_000177195.2_ASM17719v2	NC_015953	Streptomyces sp. SirexAA-E, complete sequence	2	2124444-2124548	2	CRISPRCasFinder	no		WYL,DEDDh,cas4,csa3,cas3,DinG	Orphan	TGCTCTGCCAATTGAGCTACAGGGGAT	27	0	0	NA	NA	NA	1	1	Orphan	WYL,DEDDh,cas4,csa3,cas3,DinG	NA|191aa|up_8|NC_015953.1_2113294_2113867_+,NA|104aa|down_0|NC_015953.1_2124729_2125041_+	NA|159aa|up_9|NC_015953.1_2112484_2112961_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|191aa|up_8|NC_015953.1_2113294_2113867_+	NA	NA|346aa|up_7|NC_015953.1_2113997_2115035_+	pfam06723, MreB_Mbl, MreB/Mbl protein	NA|503aa|up_6|NC_015953.1_2115052_2116561_+	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms]	NA|144aa|up_5|NC_015953.1_2116538_2116970_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|404aa|up_4|NC_015953.1_2117130_2118342_+	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism]	NA|486aa|up_3|NC_015953.1_2118376_2119834_+	PRK07787, PRK07787, acyl-CoA synthetase; Validated	NA|444aa|up_2|NC_015953.1_2119853_2121185_+	COG0777, AccD, Acetyl-CoA carboxylase beta subunit [Lipid metabolism]	NA|370aa|up_1|NC_015953.1_2121251_2122361_-	TIGR03565, alk_sulf_monoox, alkanesulfonate monooxygenase, FMNH(2)-dependent	NA|422aa|up_0|NC_015953.1_2122697_2123963_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|104aa|down_0|NC_015953.1_2124729_2125041_+	NA	NA|482aa|down_1|NC_015953.1_2125158_2126604_+	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|578aa|down_2|NC_015953.1_2126711_2128445_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|640aa|down_3|NC_015953.1_2128444_2130364_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|356aa|down_4|NC_015953.1_2130395_2131463_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|636aa|down_5|NC_015953.1_2131618_2133526_-	PRK05667, dnaG, DNA primase; Validated	NA|420aa|down_6|NC_015953.1_2133631_2134891_-	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|448aa|down_7|NC_015953.1_2135031_2136375_-	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|246aa|down_8|NC_015953.1_2136853_2137591_+	COG2949, SanA, Uncharacterized membrane protein [Function unknown]	NA|113aa|down_9|NC_015953.1_2137666_2138005_-	pfam03091, CutA1, CutA1 divalent ion tolerance protein
GCF_000177195.2_ASM17719v2	NC_015953	Streptomyces sp. SirexAA-E, complete sequence	3	2643030-2643116	3	CRISPRCasFinder	no		WYL,DEDDh,cas4,csa3,cas3,DinG	Orphan	GGGCGCGCCCGCCCGCGTACGGGCAC	26	0	0	NA	NA	NA	1	1	Orphan	WYL,DEDDh,cas4,csa3,cas3,DinG	NA,NA	NA|281aa|up_9|NC_015953.1_2632745_2633588_-	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain	NA|254aa|up_8|NC_015953.1_2633626_2634388_-	cd05362, THN_reductase-like_SDR_c, tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs	NA|321aa|up_7|NC_015953.1_2635359_2636322_+	PRK09632, PRK09632, ATP-dependent DNA ligase; Reviewed	NA|312aa|up_6|NC_015953.1_2636469_2637405_-	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku	NA|292aa|up_5|NC_015953.1_2637780_2638656_+	pfam05901, Excalibur, Excalibur calcium-binding domain	NA|281aa|up_4|NC_015953.1_2638804_2639647_+	pfam01116, F_bP_aldolase, Fructose-bisphosphate aldolase class-II	NA|260aa|up_3|NC_015953.1_2639673_2640453_+	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]	NA|191aa|up_2|NC_015953.1_2640522_2641095_-	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain	NA|491aa|up_1|NC_015953.1_2641091_2642564_-	cd17504, MFS_MMR_MDR_like, Methylenomycin A resistance protein (also called MMR peptide)-like multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|101aa|up_0|NC_015953.1_2642715_2643018_+	pfam02009, RIFIN, Rifin	NA|493aa|down_0|NC_015953.1_2643141_2644620_-	pfam04286, DUF445, Protein of unknown function (DUF445)	NA|417aa|down_1|NC_015953.1_2644762_2646013_+	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE	NA|224aa|down_2|NC_015953.1_2646038_2646710_-	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|328aa|down_3|NC_015953.1_2646792_2647776_-	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA	NA|285aa|down_4|NC_015953.1_2647785_2648640_-	pfam06182, ABC2_membrane_6, ABC-2 family transporter protein	NA|267aa|down_5|NC_015953.1_2648674_2649475_-	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only]	NA|848aa|down_6|NC_015953.1_2649629_2652173_+	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]	NA|107aa|down_7|NC_015953.1_2652215_2652536_-	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]	NA|113aa|down_8|NC_015953.1_2652739_2653078_-	smart00883, Cpn10, Chaperonin 10 Kd subunit	NA|113aa|down_9|NC_015953.1_2653200_2653539_-	pfam12277, DUF3618, Protein of unknown function (DUF3618)
GCF_000177195.2_ASM17719v2	NC_015953	Streptomyces sp. SirexAA-E, complete sequence	4	5579782-5579858	4	CRISPRCasFinder	no		WYL,DEDDh,cas4,csa3,cas3,DinG	Orphan	CCCGGACGTGCTGCCGGTCACCC	23	0	0	NA	NA	NA	1	1	Orphan	WYL,DEDDh,cas4,csa3,cas3,DinG	NA|199aa|up_1|NC_015953.1_5577328_5577925_+,NA|58aa|down_8|NC_015953.1_5589294_5589468_-	NA|376aa|up_9|NC_015953.1_5564859_5565987_+	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only]	NA|819aa|up_8|NC_015953.1_5566016_5568473_-	PRK05561, PRK05561, DNA topoisomerase 4 subunit A	NA|460aa|up_7|NC_015953.1_5568718_5570098_+	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|461aa|up_6|NC_015953.1_5570124_5571507_+	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|264aa|up_5|NC_015953.1_5571875_5572667_+	pfam01551, Peptidase_M23, Peptidase family M23	NA|235aa|up_4|NC_015953.1_5572902_5573607_+	COG1802, GntR, Transcriptional regulators [Transcription]	NA|94aa|up_3|NC_015953.1_5573788_5574070_-	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family	NA|990aa|up_2|NC_015953.1_5574286_5577256_+	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain	NA|199aa|up_1|NC_015953.1_5577328_5577925_+	NA	NA|396aa|up_0|NC_015953.1_5577924_5579112_+	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase	NA|259aa|down_0|NC_015953.1_5579875_5580652_-	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains	NA|276aa|down_1|NC_015953.1_5580916_5581744_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|352aa|down_2|NC_015953.1_5581814_5582870_-	pfam11268, DUF3071, Protein of unknown function (DUF3071)	NA|380aa|down_3|NC_015953.1_5583365_5584505_+	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|440aa|down_4|NC_015953.1_5584539_5585859_-	pfam04030, ALO, D-arabinono-1,4-lactone oxidase	NA|415aa|down_5|NC_015953.1_5585818_5587063_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|376aa|down_6|NC_015953.1_5587188_5588316_+	PRK00035, hemH, ferrochelatase; Reviewed	NA|267aa|down_7|NC_015953.1_5588395_5589196_+	cd01639, IMPase, IMPase, inositol monophosphatase and related domains	NA|58aa|down_8|NC_015953.1_5589294_5589468_-	NA	NA|218aa|down_9|NC_015953.1_5589826_5590480_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]
GCF_000177195.2_ASM17719v2	NC_015953	Streptomyces sp. SirexAA-E, complete sequence	5	6224028-6224468	1	CRT	no		WYL,DEDDh,cas4,csa3,cas3,DinG	Orphan	GNNGTCGTAGGTGTAGGTGGNNNT	24	0	0	NA	NA	NA	6	6	Orphan	WYL,DEDDh,cas4,csa3,cas3,DinG	NA|133aa|up_9|NC_015953.1_6214150_6214549_-,NA|174aa|down_0|NC_015953.1_6226003_6226525_-,NA|51aa|down_6|NC_015953.1_6234243_6234396_-	NA|133aa|up_9|NC_015953.1_6214150_6214549_-	NA	NA|116aa|up_8|NC_015953.1_6214545_6214893_-	cd17321, MFS_MMR_MDR_like, Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|67aa|up_7|NC_015953.1_6214907_6215108_+	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR	NA|156aa|up_6|NC_015953.1_6215104_6215572_+	pfam14534, DUF4440, Domain of unknown function (DUF4440)	NA|285aa|up_5|NC_015953.1_6215568_6216423_+	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family	NA|141aa|up_4|NC_015953.1_6216403_6216826_+	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function	NA|211aa|up_3|NC_015953.1_6217060_6217693_-	pfam17939, TetR_C_30, Tetracyclin repressor-like, C-terminal domain	NA|291aa|up_2|NC_015953.1_6217753_6218626_+	COG1893, ApbA, Ketopantoate reductase [Coenzyme metabolism]	NA|197aa|up_1|NC_015953.1_6219566_6220157_-	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1)	NA|171aa|up_0|NC_015953.1_6220552_6221065_-	pfam14206, Cys_rich_CPCC, Cysteine-rich CPCC	NA|174aa|down_0|NC_015953.1_6226003_6226525_-	NA	NA|587aa|down_1|NC_015953.1_6228175_6229936_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|240aa|down_2|NC_015953.1_6230344_6231064_+	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator	NA|250aa|down_3|NC_015953.1_6231313_6232063_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|150aa|down_4|NC_015953.1_6232708_6233158_-	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]	NA|256aa|down_5|NC_015953.1_6233390_6234158_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|51aa|down_6|NC_015953.1_6234243_6234396_-	NA	NA|630aa|down_7|NC_015953.1_6234678_6236568_+	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]	NA|207aa|down_8|NC_015953.1_6236642_6237263_-	pfam02525, Flavodoxin_2, Flavodoxin-like fold	NA|280aa|down_9|NC_015953.1_6237353_6238193_-	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs
GCF_000177195.2_ASM17719v2	NC_015953	Streptomyces sp. SirexAA-E, complete sequence	6	6255419-6255509	5	CRISPRCasFinder	no		WYL,DEDDh,cas4,csa3,cas3,DinG	Orphan	CGTCCTCCCCGCCGACGCGGGGGTGTTCCG	30	0	0	NA	NA	NA	1	1	Orphan	WYL,DEDDh,cas4,csa3,cas3,DinG	NA|58aa|up_6|NC_015953.1_6249085_6249259_+,NA|106aa|up_1|NC_015953.1_6254525_6254843_-,NA|116aa|up_0|NC_015953.1_6254931_6255279_-,NA|103aa|down_0|NC_015953.1_6255642_6255951_+,NA|154aa|down_7|NC_015953.1_6262230_6262692_+	NA|305aa|up_9|NC_015953.1_6242354_6243269_+	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease	NA|226aa|up_8|NC_015953.1_6243547_6244225_-	pfam11361, DUF3159, Protein of unknown function (DUF3159)	NA|272aa|up_7|NC_015953.1_6248187_6249003_+	pfam04672, Methyltransf_19, S-adenosyl methyltransferase	NA|58aa|up_6|NC_015953.1_6249085_6249259_+	NA	NA|147aa|up_5|NC_015953.1_6250045_6250486_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|297aa|up_4|NC_015953.1_6250567_6251458_+	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs	NA|279aa|up_3|NC_015953.1_6252962_6253798_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|200aa|up_2|NC_015953.1_6253818_6254418_-	cd06259, YdcF-like, YdcF-like	NA|106aa|up_1|NC_015953.1_6254525_6254843_-	NA	NA|116aa|up_0|NC_015953.1_6254931_6255279_-	NA	NA|103aa|down_0|NC_015953.1_6255642_6255951_+	NA	NA|302aa|down_1|NC_015953.1_6256004_6256910_-	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|395aa|down_2|NC_015953.1_6257233_6258418_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|425aa|down_3|NC_015953.1_6258448_6259723_+	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase	NA|216aa|down_4|NC_015953.1_6259735_6260383_+	pfam13483, Lactamase_B_3, Beta-lactamase superfamily domain	NA|260aa|down_5|NC_015953.1_6260433_6261213_+	cd09086, ExoIII-like_AP-endo, Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases	NA|260aa|down_6|NC_015953.1_6261233_6262013_-	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|154aa|down_7|NC_015953.1_6262230_6262692_+	NA	NA|248aa|down_8|NC_015953.1_6262793_6263537_+	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|304aa|down_9|NC_015953.1_6263551_6264463_+	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold
