assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003860285.1_ASM386028v1	CP034192	Bifidobacterium breve strain lw01 chromosome, complete genome	1	126534-126611	1	CRISPRCasFinder	no		DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	TACTGGTGGTTTTGCCCCGCTGAGG	25	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|264aa|down_3|CP034192.1_131864_132656_-	NA|314aa|up_9|CP034192.1_111734_112676_+	PRK03072, PRK03072, heat shock protein HtpX; Provisional	NA|312aa|up_8|CP034192.1_112941_113877_+	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter	NA|356aa|up_7|CP034192.1_113939_115007_+	PRK09197, PRK09197, fructose-bisphosphate aldolase; Provisional	NA|429aa|up_6|CP034192.1_115160_116447_+	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional	NA|528aa|up_5|CP034192.1_116470_118054_+	cd01031, EriC, ClC chloride channel EriC	NA|401aa|up_4|CP034192.1_118081_119284_+	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]	NA|356aa|up_3|CP034192.1_118611_119679_+	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB)	NA|509aa|up_2|CP034192.1_121817_123344_+	PRK13840, PRK13840, sucrose phosphorylase; Provisional	NA|545aa|up_1|CP034192.1_123549_125184_+	cd06174, MFS, Major Facilitator Superfamily	NA|351aa|up_0|CP034192.1_125253_126306_+	cd06291, PBP1_Qymf-like, ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs	NA|456aa|down_0|CP034192.1_127291_128659_+	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily	NA|351aa|down_1|CP034192.1_129053_130106_+	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional	NA|351aa|down_2|CP034192.1_130535_131588_+	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional	NA|264aa|down_3|CP034192.1_131864_132656_-	NA	NA|343aa|down_4|CP034192.1_132652_133681_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|605aa|down_5|CP034192.1_133887_135702_-	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins	NA|344aa|down_6|CP034192.1_135973_137005_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|1471aa|down_7|CP034192.1_137878_142291_+	pfam17802, SpaA, Prealbumin-like fold domain	NA|615aa|down_8|CP034192.1_142395_144240_+	pfam16569, GramPos_pilinBB, Gram-positive pilin backbone subunit 2, Cna-B-like domain	NA|320aa|down_9|CP034192.1_144496_145456_+	cd05827, Sortase_C, Sortase domain found in class C sortases
GCA_003860285.1_ASM386028v1	CP034192	Bifidobacterium breve strain lw01 chromosome, complete genome	2	126690-126870	2	CRISPRCasFinder	no		DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	TACTGGTGGTTTTGCCCCGCTGAGG	25	0	0	NA	NA	NA	3	3	Orphan	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|264aa|down_3|CP034192.1_131864_132656_-	NA|314aa|up_9|CP034192.1_111734_112676_+	PRK03072, PRK03072, heat shock protein HtpX; Provisional	NA|312aa|up_8|CP034192.1_112941_113877_+	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter	NA|356aa|up_7|CP034192.1_113939_115007_+	PRK09197, PRK09197, fructose-bisphosphate aldolase; Provisional	NA|429aa|up_6|CP034192.1_115160_116447_+	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional	NA|528aa|up_5|CP034192.1_116470_118054_+	cd01031, EriC, ClC chloride channel EriC	NA|401aa|up_4|CP034192.1_118081_119284_+	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]	NA|356aa|up_3|CP034192.1_118611_119679_+	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB)	NA|509aa|up_2|CP034192.1_121817_123344_+	PRK13840, PRK13840, sucrose phosphorylase; Provisional	NA|545aa|up_1|CP034192.1_123549_125184_+	cd06174, MFS, Major Facilitator Superfamily	NA|351aa|up_0|CP034192.1_125253_126306_+	cd06291, PBP1_Qymf-like, ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs	NA|456aa|down_0|CP034192.1_127291_128659_+	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily	NA|351aa|down_1|CP034192.1_129053_130106_+	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional	NA|351aa|down_2|CP034192.1_130535_131588_+	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional	NA|264aa|down_3|CP034192.1_131864_132656_-	NA	NA|343aa|down_4|CP034192.1_132652_133681_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|605aa|down_5|CP034192.1_133887_135702_-	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins	NA|344aa|down_6|CP034192.1_135973_137005_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|1471aa|down_7|CP034192.1_137878_142291_+	pfam17802, SpaA, Prealbumin-like fold domain	NA|615aa|down_8|CP034192.1_142395_144240_+	pfam16569, GramPos_pilinBB, Gram-positive pilin backbone subunit 2, Cna-B-like domain	NA|320aa|down_9|CP034192.1_144496_145456_+	cd05827, Sortase_C, Sortase domain found in class C sortases
GCA_003860285.1_ASM386028v1	CP034192	Bifidobacterium breve strain lw01 chromosome, complete genome	3	644768-644841	3	CRISPRCasFinder	no		DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	TGGGGACTGCTCAATCTACCGAC	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	NA,NA|77aa|down_5|CP034192.1_651961_652192_-	NA|914aa|up_9|CP034192.1_631082_633824_+	pfam02057, Glyco_hydro_59, Glycosyl hydrolase family 59	NA|528aa|up_8|CP034192.1_633857_635441_+	COG2211, MelB, Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]	NA|481aa|up_7|CP034192.1_635505_636948_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|161aa|up_6|CP034192.1_637000_637483_-	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism]	NA|416aa|up_5|CP034192.1_637595_638843_-	PRK15072, PRK15072, D-galactonate dehydratase family protein	NA|465aa|up_4|CP034192.1_638941_640336_-	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]	NA|476aa|up_3|CP034192.1_640371_641799_-	PRK02925, PRK02925, glucuronate isomerase; Reviewed	NA|131aa|up_2|CP034192.1_641829_642222_-	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]	NA|338aa|up_1|CP034192.1_642451_643465_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|334aa|up_0|CP034192.1_643609_644611_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|476aa|down_0|CP034192.1_644904_646332_-	TIGR00909, putative_amino_acid_transporter, amino acid transporter	NA|453aa|down_1|CP034192.1_646523_647882_+	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase	NA|429aa|down_2|CP034192.1_647921_649208_+	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|701aa|down_3|CP034192.1_649391_651494_+	PRK05667, dnaG, DNA primase; Validated	NA|141aa|down_4|CP034192.1_651542_651965_-	pfam13470, PIN_3, PIN domain	NA|77aa|down_5|CP034192.1_651961_652192_-	NA	NA|292aa|down_6|CP034192.1_652402_653278_+	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA|213aa|down_7|CP034192.1_653467_654106_+	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA|508aa|down_8|CP034192.1_654163_655687_+	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|393aa|down_9|CP034192.1_655767_656946_+	cd01117, YbiR_permease, Putative anion permease YbiR
GCA_003860285.1_ASM386028v1	CP034192	Bifidobacterium breve strain lw01 chromosome, complete genome	4	1672781-1674916	4,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,cas4,cas7,cas8c,cas5,cas3	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	 Type I-U?,Type I-C,Type I-U	ATTTCAATCCACGCTCCCCGGATGGGGAGCGAC,ATTTCAATCCACGCTCCCCGGATGGGGAGCGAC,ATTTCAATCCACGCTCCCCGGATGGGGAGCGAC	33,33,33	1	1	1674039-1674072	CP034192.1_1071997-1072030	I-C:I-C:I-C	31,31,30	31	TypeI-U?,TypeI-C,TypeI-U	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	NA|78aa|up_5|CP034192.1_1665527_1665761_-,NA|69aa|down_0|CP034192.1_1675356_1675563_-,NA|78aa|down_1|CP034192.1_1675740_1675974_-	NA|525aa|up_9|CP034192.1_1660076_1661651_-	TIGR03689, pup_AAA, proteasome ATPase	NA|232aa|up_8|CP034192.1_1661705_1662401_-	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|251aa|up_7|CP034192.1_1662421_1663174_+	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p	NA|770aa|up_6|CP034192.1_1663221_1665531_+	PRK14873, PRK14873, primosomal protein N'	NA|78aa|up_5|CP034192.1_1665527_1665761_-	NA	NA|235aa|up_4|CP034192.1_1665776_1666481_+	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive	NA|338aa|up_3|CP034192.1_1666619_1667633_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed	NA|621aa|up_2|CP034192.1_1667925_1669788_-	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional	NA|95aa|up_1|CP034192.1_1669954_1670239_+	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed	NA|407aa|up_0|CP034192.1_1670524_1671745_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|69aa|down_0|CP034192.1_1675356_1675563_-	NA	NA|78aa|down_1|CP034192.1_1675740_1675974_-	NA	cas2|97aa|down_2|CP034192.1_1676496_1676787_-	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	cas1|344aa|down_3|CP034192.1_1676843_1677875_-	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG	cas4|230aa|down_4|CP034192.1_1677876_1678566_-	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4	cas7|284aa|down_5|CP034192.1_1678604_1679456_-	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7	cas8c|653aa|down_6|CP034192.1_1679459_1681418_-	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1)	cas5|235aa|down_7|CP034192.1_1681420_1682125_-	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas3|813aa|down_8|CP034192.1_1682131_1684570_-	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	NA|230aa|down_9|CP034192.1_1685228_1685918_-	pfam13542, HTH_Tnp_ISL3, Helix-turn-helix domain of transposase family ISL3
GCA_003860285.1_ASM386028v1	CP034192	Bifidobacterium breve strain lw01 chromosome, complete genome	5	2050584-2050730	5	CRISPRCasFinder	no		DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	AATCTCCTAAAATCCTGTCACTAAG	25	2	2	2050609-2050644|2050670-2050705	CP034192.1_2051946-2051981|CP034192.1_2052007-2052042	NA	2	2	Orphan	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	NA|75aa|up_9|CP034192.1_2028905_2029130_-,NA|702aa|up_3|CP034192.1_2045775_2047881_+,NA|318aa|down_0|CP034192.1_2050844_2051798_+	NA|75aa|up_9|CP034192.1_2028905_2029130_-	NA	NA|3146aa|up_8|CP034192.1_2030570_2040008_-	COG4982, COG4982, 3-oxoacyl-[acyl-carrier protein]	NA|541aa|up_7|CP034192.1_2040047_2041670_-	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]	NA|623aa|up_6|CP034192.1_2041662_2043531_-	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|200aa|up_5|CP034192.1_2044043_2044643_+	pfam02632, BioY, BioY family	NA|320aa|up_4|CP034192.1_2044644_2045604_-	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]	NA|702aa|up_3|CP034192.1_2045775_2047881_+	NA	NA|286aa|up_2|CP034192.1_2047959_2048817_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|231aa|up_1|CP034192.1_2049088_2049781_-	PRK05424, rplA, 50S ribosomal protein L1; Validated	NA|144aa|up_0|CP034192.1_2049796_2050228_-	PRK00140, rplK, 50S ribosomal protein L11; Validated	NA|318aa|down_0|CP034192.1_2050844_2051798_+	NA	NA|276aa|down_1|CP034192.1_2052214_2053042_-	PRK05609, nusG, transcription antitermination protein NusG; Validated	NA|76aa|down_2|CP034192.1_2053074_2053302_-	PRK07597, secE, preprotein translocase subunit SecE; Reviewed	NA|402aa|down_3|CP034192.1_2053631_2054837_-	PRK05764, PRK05764, aspartate aminotransferase; Provisional	NA|421aa|down_4|CP034192.1_2054978_2056241_+	cd10966, CE4_yadE_5s, Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins	NA|378aa|down_5|CP034192.1_2056318_2057452_-	PRK05429, PRK05429, gamma-glutamyl kinase; Provisional	NA|564aa|down_6|CP034192.1_2057558_2059250_-	PRK12296, obgE, GTPase CgtA; Reviewed	NA|84aa|down_7|CP034192.1_2059316_2059568_-	PRK05435, rpmA, 50S ribosomal protein L27; Validated	NA|103aa|down_8|CP034192.1_2059590_2059899_-	PRK05573, rplU, 50S ribosomal protein L21; Validated	NA|1017aa|down_9|CP034192.1_2060085_2063136_-	TIGR00757, Ribonuclease_E/G-like_protein, ribonuclease, Rne/Rng family
GCA_003860285.1_ASM386028v1	CP034192	Bifidobacterium breve strain lw01 chromosome, complete genome	6	2186942-2187026	6	CRISPRCasFinder	no		DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	Orphan	CCTTCCCGAATATGTACCACTGAC	24	0	0	NA	NA	NA	1	1	Orphan	DEDDh,cas3,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	NA|80aa|up_4|CP034192.1_2180822_2181062_+,NA|98aa|down_9|CP034192.1_2203741_2204035_-	NA|314aa|up_9|CP034192.1_2173415_2174357_+	TIGR04182, glyco_TIGR04182, glycosyltransferase, TIGR04182 family	NA|600aa|up_8|CP034192.1_2174397_2176197_-	cd06414, GH25_LytC-like, The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains	NA|502aa|up_7|CP034192.1_2176471_2177977_-	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|487aa|up_6|CP034192.1_2178281_2179742_+	pfam02687, FtsX, FtsX-like permease family	NA|247aa|up_5|CP034192.1_2180182_2180923_+	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|80aa|up_4|CP034192.1_2180822_2181062_+	NA	NA|255aa|up_3|CP034192.1_2181283_2182048_+	TIGR00295, Uncharacterized_protein_MJ0778, TIGR00295 family protein	NA|287aa|up_2|CP034192.1_2182176_2183037_-	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|804aa|up_1|CP034192.1_2183320_2185732_-	pfam02705, K_trans, K+ potassium transporter	NA|320aa|up_0|CP034192.1_2185930_2186890_-	cd01310, TatD_DNAse, TatD like proteins;  E	NA|602aa|down_0|CP034192.1_2187144_2188950_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|621aa|down_1|CP034192.1_2189146_2191009_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|466aa|down_2|CP034192.1_2191499_2192897_+	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|457aa|down_3|CP034192.1_2193130_2194501_-	pfam13635, DUF4143, Domain of unknown function (DUF4143)	NA|578aa|down_4|CP034192.1_2195908_2197642_-	cd08501, PBP2_Lpqw, The substrate-binding domain of mycobacterial lipoprotein Lpqw contains type 2 periplasmic binding fold	NA|713aa|down_5|CP034192.1_2197673_2199812_-	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|333aa|down_6|CP034192.1_2199829_2200828_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|307aa|down_7|CP034192.1_2200852_2201773_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|510aa|down_8|CP034192.1_2202131_2203661_+	cd00585, Peptidase_C1B, Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC)	NA|98aa|down_9|CP034192.1_2203741_2204035_-	NA
