assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003856575.1_ASM385657v1	CP023834	Escherichia coli strain 4/2-1 chromosome, complete genome	1	424273-424417	1	CRISPRCasFinder	no		DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	ATGCCTGATGCGACGCTTGCCGCGTCTTATCAGGCCTACAAAA	43	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA|66aa|up_5|CP023834.1_420397_420595_+,NA	NA|270aa|up_9|CP023834.1_418031_418841_-	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed	NA|153aa|up_8|CP023834.1_418960_419419_+	PRK00124, PRK00124, YaiI/YqxD family protein	NA|175aa|up_7|CP023834.1_419601_420126_+	PRK03731, aroL, shikimate kinase AroL	NA|64aa|up_6|CP023834.1_420175_420367_+	PRK10380, PRK10380, hypothetical protein; Provisional	NA|66aa|up_5|CP023834.1_420397_420595_+	NA	NA|226aa|up_4|CP023834.1_420624_421302_+	PRK10481, PRK10481, hypothetical protein; Provisional	NA|95aa|up_3|CP023834.1_421373_421658_+	PRK10579, PRK10579, pyrimidine/purine nucleoside phosphorylase	NA|94aa|up_2|CP023834.1_421865_422147_+	pfam10971, DUF2773, Protein of unknown function (DUF2773)	NA|304aa|up_1|CP023834.1_422304_423216_-	COG2974, RdgC, DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]	NA|303aa|up_0|CP023834.1_423340_424249_+	PRK09557, PRK09557, fructokinase; Reviewed	NA|395aa|down_0|CP023834.1_424493_425678_-	PRK10091, PRK10091, MFS transport protein AraJ; Provisional	NA|1049aa|down_1|CP023834.1_425803_428950_-	PRK10246, PRK10246, exonuclease subunit SbcC; Provisional	NA|401aa|down_2|CP023834.1_428946_430149_-	PRK10966, PRK10966, exonuclease subunit SbcD; Provisional	NA|230aa|down_3|CP023834.1_430338_431028_+	PRK10161, PRK10161, phosphate response regulator transcription factor PhoB	NA|432aa|down_4|CP023834.1_431085_432381_+	PRK11006, phoR, phosphate regulon sensor histidine kinase PhoR	NA|440aa|down_5|CP023834.1_432787_434107_+	PRK15433, PRK15433, branched-chain amino acid transporter carrier protein BrnQ	NA|458aa|down_6|CP023834.1_434182_435556_+	PRK10580, proY, putative proline-specific permease; Provisional	NA|605aa|down_7|CP023834.1_435714_437529_+	PRK10785, PRK10785, maltodextrin glucosidase; Provisional	NA|194aa|down_8|CP023834.1_437533_438115_-	PRK10045, PRK10045, ACP phosphodiesterase	NA|357aa|down_9|CP023834.1_438207_439278_+	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional
GCA_003856575.1_ASM385657v1	CP023834	Escherichia coli strain 4/2-1 chromosome, complete genome	2	564459-564555	2	CRISPRCasFinder	no		DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	GCTTGACGCGTCTTATCAGGCCTACAA	27	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA	NA|454aa|up_9|CP023834.1_552239_553601_+	PRK08044, PRK08044, allantoinase AllB	NA|434aa|up_8|CP023834.1_553657_554959_+	PRK11412, PRK11412, uracil/xanthine transporter	NA|382aa|up_7|CP023834.1_554980_556126_+	PRK09932, PRK09932, glycerate 3-kinase	NA|262aa|up_6|CP023834.1_556353_557139_-	TIGR03214, ura-cupin, putative allantoin catabolism protein	NA|412aa|up_5|CP023834.1_557149_558385_-	TIGR03176, AllC, allantoate amidohydrolase	NA|350aa|up_4|CP023834.1_558406_559456_-	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional	NA|556aa|up_3|CP023834.1_559772_561440_+	PRK06091, PRK06091, membrane protein FdrA; Validated	NA|420aa|up_2|CP023834.1_561449_562709_+	pfam06545, DUF1116, Protein of unknown function (DUF1116)	NA|272aa|up_1|CP023834.1_562719_563535_+	pfam11392, DUF2877, Protein of unknown function (DUF2877)	NA|298aa|up_0|CP023834.1_563531_564425_+	PRK09411, PRK09411, carbamate kinase; Reviewed	NA|356aa|down_0|CP023834.1_564619_565687_-	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed	NA|170aa|down_1|CP023834.1_565683_566193_-	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]	NA|241aa|down_2|CP023834.1_566310_567033_-	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional	NA|165aa|down_3|CP023834.1_567035_567530_-	PRK10791, PRK10791, peptidylprolyl isomerase B	NA|462aa|down_4|CP023834.1_567703_569089_+	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated	NA|174aa|down_5|CP023834.1_569124_569646_-	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only]	NA|71aa|down_6|CP023834.1_569753_569966_-	PRK11507, PRK11507, ribosome-associated protein YbcJ	NA|289aa|down_7|CP023834.1_569967_570834_-	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	NA|181aa|down_8|CP023834.1_571304_571847_+	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA	NA|231aa|down_9|CP023834.1_572066_572759_+	PRK15195, PRK15195, molecular chaperone FimC
GCA_003856575.1_ASM385657v1	CP023834	Escherichia coli strain 4/2-1 chromosome, complete genome	3	2392320-2392446	3	CRISPRCasFinder	no		DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	TTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGC	39	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA	NA|395aa|up_9|CP023834.1_2371227_2372412_+	PRK05790, PRK05790, putative acyltransferase; Provisional	NA|259aa|up_8|CP023834.1_2372485_2373262_-	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown]	NA|550aa|up_7|CP023834.1_2373266_2374916_-	COG5445, COG5445, Predicted secreted protein [Function unknown]	NA|1535aa|up_6|CP023834.1_2374916_2379521_-	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only]	NA|208aa|up_5|CP023834.1_2379454_2380078_-	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown]	NA|563aa|up_4|CP023834.1_2380074_2381763_-	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown]	NA|876aa|up_3|CP023834.1_2381911_2384539_-	PRK05560, PRK05560, DNA gyrase subunit A; Validated	NA|241aa|up_2|CP023834.1_2384685_2385408_+	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	NA|1251aa|up_1|CP023834.1_2385535_2389288_-	PRK09752, PRK09752, AIDA-I family autotransporter YfaL	NA|762aa|up_0|CP023834.1_2389983_2392269_+	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha	NA|377aa|down_0|CP023834.1_2392502_2393633_+	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed	NA|85aa|down_1|CP023834.1_2393632_2393887_+	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein	NA|217aa|down_2|CP023834.1_2393940_2394591_-	PRK09902, PRK09902, lipopolysaccharide kinase InaA	NA|69aa|down_3|CP023834.1_2394805_2395012_+	PRK09729, PRK09729, hypothetical protein; Provisional	NA|359aa|down_4|CP023834.1_2395053_2396130_-	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional	NA|453aa|down_5|CP023834.1_2396134_2397493_-	PRK11273, glpT, glycerol-3-phosphate transporter	NA|543aa|down_6|CP023834.1_2397765_2399394_+	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA|420aa|down_7|CP023834.1_2399383_2400643_+	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]	NA|397aa|down_8|CP023834.1_2400639_2401830_+	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	NA|300aa|down_9|CP023834.1_2402022_2402922_+	PRK09956, PRK09956, ISNCY family transposase
GCA_003856575.1_ASM385657v1	CP023834	Escherichia coli strain 4/2-1 chromosome, complete genome	4	2886739-2887440	4,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Type I-E	CGGTTTATCCCCGCTGGCGCGGGGAACTC,CGGTTTATCCCCGCTGGCGCGGGGAACTC,CGGTTTATCCCCGCTGGCGCGGGGAACTC	29,29,29	0	0	NA	NA	I-E:I-E:I-E	11,11,8	11	TypeI-E	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA	NA|254aa|up_9|CP023834.1_2878550_2879312_-	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional	NA|350aa|up_8|CP023834.1_2879292_2880342_-	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|160aa|up_7|CP023834.1_2880338_2880818_-	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|237aa|up_6|CP023834.1_2880817_2881528_-	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|104aa|up_5|CP023834.1_2881546_2881858_-	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|108aa|up_4|CP023834.1_2882051_2882375_-	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|202aa|up_3|CP023834.1_2882424_2883030_-	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|476aa|up_2|CP023834.1_2883029_2884457_-	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|303aa|up_1|CP023834.1_2884458_2885367_-	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|346aa|up_0|CP023834.1_2885618_2886656_+	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	cas2|95aa|down_0|CP023834.1_2887545_2887830_-	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	cas1|306aa|down_1|CP023834.1_2887831_2888749_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|200aa|down_2|CP023834.1_2888764_2889364_-	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas5|225aa|down_3|CP023834.1_2889350_2890025_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|364aa|down_4|CP023834.1_2890027_2891119_-	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cse2gr11|161aa|down_5|CP023834.1_2891131_2891614_-	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2	cas8e|495aa|down_6|CP023834.1_2891606_2893091_-	PRK09693, PRK09693, Cascade antiviral complex protein; Validated	cas3|889aa|down_7|CP023834.1_2893529_2896196_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|245aa|down_8|CP023834.1_2896554_2897289_-	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|571aa|down_9|CP023834.1_2897363_2899076_-	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit
GCA_003856575.1_ASM385657v1	CP023834	Escherichia coli strain 4/2-1 chromosome, complete genome	5	2912989-2913323	5,2,2	CRISPRCasFinder,PILER-CR,CRT	no	cas3	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Unclear	TCGGTTTATCCCCGCTGGCGCGGGGAACAC,GGTTTATCCCCGCTGGCGCGGGGAAC,GGTTTATCCCCGCTGGCGCGGGGAACAC	30,26,28	0	0	NA	NA	I-E:I-E:I-E	5,5,5	5	Unclear	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA|47aa|down_1|CP023834.1_2914472_2914613_+	NA|424aa|up_9|CP023834.1_2901633_2902905_+	PRK10015, PRK10015, oxidoreductase; Provisional	NA|87aa|up_8|CP023834.1_2902895_2903156_+	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|192aa|up_7|CP023834.1_2903172_2903748_+	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|287aa|up_6|CP023834.1_2903895_2904756_-	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|260aa|up_5|CP023834.1_2904752_2905532_-	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|446aa|up_4|CP023834.1_2905509_2906847_-	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|485aa|up_3|CP023834.1_2906940_2908395_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|262aa|up_2|CP023834.1_2908464_2909250_-	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|426aa|up_1|CP023834.1_2909568_2910846_+	cd06174, MFS, Major Facilitator Superfamily	NA|493aa|up_0|CP023834.1_2910872_2912351_+	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|224aa|down_0|CP023834.1_2913662_2914334_-	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|47aa|down_1|CP023834.1_2914472_2914613_+	NA	NA|291aa|down_2|CP023834.1_2914626_2915499_+	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|433aa|down_3|CP023834.1_2915558_2916857_-	PRK00077, eno, enolase; Provisional	NA|546aa|down_4|CP023834.1_2916944_2918582_-	PRK05380, pyrG, CTP synthetase; Validated	NA|264aa|down_5|CP023834.1_2918809_2919601_-	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|112aa|down_6|CP023834.1_2919671_2920007_-	PRK09907, PRK09907, endoribonuclease MazF	NA|83aa|down_7|CP023834.1_2920006_2920255_-	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|745aa|down_8|CP023834.1_2920332_2922567_-	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|434aa|down_9|CP023834.1_2922614_2923916_-	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
GCA_003856575.1_ASM385657v1	CP023834	Escherichia coli strain 4/2-1 chromosome, complete genome	6	4602901-4603050	6	CRISPRCasFinder	no		DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	54	0	0	NA	NA	NA	1	1	Orphan	DEDDh,DinG,cas3,RT,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA|146aa|down_6|CP023834.1_4611697_4612135_+	NA|132aa|up_9|CP023834.1_4591448_4591844_-	cd02198, YjgH_like, YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function	NA|238aa|up_8|CP023834.1_4591974_4592688_-	PRK12742, PRK12742, SDR family oxidoreductase	NA|198aa|up_7|CP023834.1_4592758_4593352_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|151aa|up_6|CP023834.1_4593496_4593949_+	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]	NA|335aa|up_5|CP023834.1_4595871_4596876_-	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional	NA|139aa|up_4|CP023834.1_4597037_4597454_+	PRK11191, PRK11191, ribonuclease E inhibitor RraB	NA|168aa|up_3|CP023834.1_4597499_4598003_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|396aa|up_2|CP023834.1_4598195_4599383_+	COG4269, COG4269, Predicted membrane protein [Function unknown]	NA|952aa|up_1|CP023834.1_4599434_4602290_-	PRK05729, valS, valyl-tRNA synthetase; Reviewed	NA|148aa|up_0|CP023834.1_4602289_4602733_-	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated	NA|504aa|down_0|CP023834.1_4603086_4604598_-	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional	NA|367aa|down_1|CP023834.1_4604864_4605965_+	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional	NA|361aa|down_2|CP023834.1_4605964_4607047_+	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional	NA|501aa|down_3|CP023834.1_4607207_4608710_-	pfam05872, DUF853, Bacterial protein of unknown function (DUF853)	NA|340aa|down_4|CP023834.1_4608837_4609857_-	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD)	NA|418aa|down_5|CP023834.1_4610300_4611554_+	PRK09692, PRK09692, integrase; Provisional	NA|146aa|down_6|CP023834.1_4611697_4612135_+	NA	NA|891aa|down_7|CP023834.1_4612127_4614800_+	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]	NA|514aa|down_8|CP023834.1_4615214_4616756_+	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|249aa|down_9|CP023834.1_4616770_4617517_+	pfam01695, IstB_IS21, IstB-like ATP binding protein
