assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	1	1855538-1855626	1	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GCGACTGCGGACCGGCCGTGGCTG	24	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|154aa|up_6|CP033581.1_1844879_1845341_+,NA|308aa|up_4|CP033581.1_1850138_1851062_-,NA|508aa|up_3|CP033581.1_1851159_1852683_-,NA|466aa|down_1|CP033581.1_1856516_1857914_-,NA|65aa|down_3|CP033581.1_1859007_1859202_+	NA|137aa|up_9|CP033581.1_1840639_1841050_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|146aa|up_8|CP033581.1_1841060_1841498_-	pfam03259, Robl_LC7, Roadblock/LC7 domain	NA|999aa|up_7|CP033581.1_1841494_1844491_-	pfam08376, NIT, Nitrate and nitrite sensing	NA|154aa|up_6|CP033581.1_1844879_1845341_+	NA	NA|1554aa|up_5|CP033581.1_1845423_1850085_-	TIGR02680, conserved_hypothetical_protein, TIGR02680 family protein	NA|308aa|up_4|CP033581.1_1850138_1851062_-	NA	NA|508aa|up_3|CP033581.1_1851159_1852683_-	NA	NA|265aa|up_2|CP033581.1_1852844_1853639_+	pfam03746, LamB_YcsF, LamB/YcsF family	NA|204aa|up_1|CP033581.1_1853635_1854247_+	pfam02682, CT_C_D, Carboxyltransferase domain, subdomain C and D	NA|309aa|up_0|CP033581.1_1854243_1855170_+	pfam02626, CT_A_B, Carboxyltransferase domain, subdomain A and B	NA|136aa|down_0|CP033581.1_1855704_1856112_+	pfam11528, DUF3224, Protein of unknown function (DUF3224)	NA|466aa|down_1|CP033581.1_1856516_1857914_-	NA	NA|147aa|down_2|CP033581.1_1858256_1858697_-	sd00045, ANK, ankyrin repeats	NA|65aa|down_3|CP033581.1_1859007_1859202_+	NA	NA|544aa|down_4|CP033581.1_1859281_1860913_+	cd01120, RecA-like_NTPases, RecA-like NTPases	NA|501aa|down_5|CP033581.1_1860948_1862451_-	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|257aa|down_6|CP033581.1_1862633_1863404_+	cd08561, GDPD_cytoplasmic_ScUgpQ2_like, Glycerophosphodiester phosphodiesterase domain of Streptomyces coelicolor cytoplasmic phosphodiesterases UgpQ2 and similar proteins	NA|458aa|down_7|CP033581.1_1863469_1864843_+	cd17482, MFS_YxiO_like, Bacillus subtilis YxiO, Listeria monocytogenes BtlA, and similar transporters of the Major Facilitator Superfamily	NA|125aa|down_8|CP033581.1_1865166_1865541_+	pfam13397, RbpA, RNA polymerase-binding protein	NA|193aa|down_9|CP033581.1_1865643_1866222_-	pfam04186, FxsA, FxsA cytoplasmic membrane protein
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	2	1872835-1873038	2	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GCCGGCCCGCACACGGCTCCGGGCTCAGCGCTCCGAGGGCGCCGCGGCG	49	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|149aa|up_2|CP033581.1_1869796_1870243_+,NA|378aa|up_0|CP033581.1_1871440_1872574_-,NA|59aa|down_2|CP033581.1_1875896_1876073_-	NA|257aa|up_9|CP033581.1_1862633_1863404_+	cd08561, GDPD_cytoplasmic_ScUgpQ2_like, Glycerophosphodiester phosphodiesterase domain of Streptomyces coelicolor cytoplasmic phosphodiesterases UgpQ2 and similar proteins	NA|458aa|up_8|CP033581.1_1863469_1864843_+	cd17482, MFS_YxiO_like, Bacillus subtilis YxiO, Listeria monocytogenes BtlA, and similar transporters of the Major Facilitator Superfamily	NA|125aa|up_7|CP033581.1_1865166_1865541_+	pfam13397, RbpA, RNA polymerase-binding protein	NA|193aa|up_6|CP033581.1_1865643_1866222_-	pfam04186, FxsA, FxsA cytoplasmic membrane protein	NA|287aa|up_5|CP033581.1_1866302_1867163_-	cd06442, DPM1_like, DPM1_like represents putative enzymes similar to eukaryotic DPM1	NA|545aa|up_4|CP033581.1_1867433_1869068_-	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases	NA|150aa|up_3|CP033581.1_1869136_1869586_-	smart00344, HTH_ASNC, helix_turn_helix ASNC type	NA|149aa|up_2|CP033581.1_1869796_1870243_+	NA	NA|369aa|up_1|CP033581.1_1870268_1871375_-	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins	NA|378aa|up_0|CP033581.1_1871440_1872574_-	NA	NA|391aa|down_0|CP033581.1_1873793_1874966_-	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|232aa|down_1|CP033581.1_1875114_1875810_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|59aa|down_2|CP033581.1_1875896_1876073_-	NA	NA|141aa|down_3|CP033581.1_1876249_1876672_-	pfam03779, SPW, SPW repeat	NA|457aa|down_4|CP033581.1_1876790_1878161_-	cd02549, Peptidase_C39A, A sub-family of peptidase family C39	NA|221aa|down_5|CP033581.1_1878306_1878969_+	PRK06547, PRK06547, hypothetical protein; Provisional	NA|652aa|down_6|CP033581.1_1879346_1881302_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|365aa|down_7|CP033581.1_1881354_1882449_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|459aa|down_8|CP033581.1_1882445_1883822_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|155aa|down_9|CP033581.1_1884022_1884487_-	pfam10756, bPH_6, Bacterial PH domain
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	3	1982424-1982505	3	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GGTCGGGGCGGAGCCCGGTGCCCGGC	26	1	10	1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479|1982450-1982479	CP033581.1_2832977-2832948|CP033581.1_2844111-2844140|CP033581.1_1361332-1361361|CP033581.1_2013290-2013319|CP033581.1_2844057-2844086|CP033581.1_2844282-2844253|CP033581.1_4267163-4267134|CP033581.1_4274746-4274717|CP033581.1_6056215-6056186|CP033581.1_6056319-6056290	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|194aa|up_7|CP033581.1_1975572_1976154_-,NA|65aa|down_5|CP033581.1_1986851_1987046_-	NA|1103aa|up_9|CP033581.1_1971117_1974426_-	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|386aa|up_8|CP033581.1_1974418_1975576_-	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit	NA|194aa|up_7|CP033581.1_1975572_1976154_-	NA	NA|429aa|up_6|CP033581.1_1976150_1977437_-	PRK09357, pyrC, dihydroorotase; Validated	NA|331aa|up_5|CP033581.1_1977439_1978432_-	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit	NA|193aa|up_4|CP033581.1_1978546_1979125_-	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA|167aa|up_3|CP033581.1_1979372_1979873_+	cd16837, BldD_C_like, C-terminal domain of BldD and similar transcription factors	NA|145aa|up_2|CP033581.1_1980055_1980490_-	PRK00202, nusB, transcription antitermination factor NusB	NA|189aa|up_1|CP033581.1_1980492_1981059_-	PRK00529, PRK00529, elongation factor P; Validated	NA|369aa|up_0|CP033581.1_1981118_1982225_-	cd01092, APP-like, Similar to Prolidase and Aminopeptidase P	NA|257aa|down_0|CP033581.1_1982649_1983420_-	pfam13671, AAA_33, AAA domain	NA|147aa|down_1|CP033581.1_1983512_1983953_-	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase	NA|364aa|down_2|CP033581.1_1983949_1985041_-	PRK00002, aroB, 3-dehydroquinate synthase; Reviewed	NA|173aa|down_3|CP033581.1_1985037_1985556_-	PRK00131, aroK, shikimate kinase; Reviewed	NA|395aa|down_4|CP033581.1_1985552_1986737_-	PRK05382, PRK05382, chorismate synthase; Validated	NA|65aa|down_5|CP033581.1_1986851_1987046_-	NA	NA|275aa|down_6|CP033581.1_1987084_1987909_-	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed	NA|608aa|down_7|CP033581.1_1987915_1989739_-	pfam02618, YceG, YceG-like family	NA|157aa|down_8|CP033581.1_1989867_1990338_-	pfam03652, RuvX, Holliday junction resolvase	NA|893aa|down_9|CP033581.1_1990340_1993019_-	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	4	2401785-2401880	4	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	CAGTGCCGACAAGGCCCGGGGGCGCGGGG	29	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|74aa|up_9|CP033581.1_2390747_2390969_+,NA|67aa|up_7|CP033581.1_2392382_2392583_+,NA|507aa|up_5|CP033581.1_2394261_2395782_-,NA|86aa|up_3|CP033581.1_2398140_2398398_+,NA|455aa|down_2|CP033581.1_2402875_2404240_-	NA|74aa|up_9|CP033581.1_2390747_2390969_+	NA	NA|427aa|up_8|CP033581.1_2391022_2392303_+	pfam02342, TerD, TerD domain	NA|67aa|up_7|CP033581.1_2392382_2392583_+	NA	NA|480aa|up_6|CP033581.1_2392656_2394096_-	pfam05787, DUF839, Bacterial protein of unknown function (DUF839)	NA|507aa|up_5|CP033581.1_2394261_2395782_-	NA	NA|614aa|up_4|CP033581.1_2396124_2397966_+	COG2374, COG2374, Predicted extracellular nuclease [General function prediction only]	NA|86aa|up_3|CP033581.1_2398140_2398398_+	NA	NA|327aa|up_2|CP033581.1_2398518_2399499_-	TIGR03535, DapD_actino, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA|411aa|up_1|CP033581.1_2399508_2400741_-	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|294aa|up_0|CP033581.1_2400838_2401720_+	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|188aa|down_0|CP033581.1_2401939_2402503_-	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown]	NA|108aa|down_1|CP033581.1_2402502_2402826_-	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]	NA|455aa|down_2|CP033581.1_2402875_2404240_-	NA	NA|115aa|down_3|CP033581.1_2404390_2404735_-	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]	NA|154aa|down_4|CP033581.1_2404731_2405193_-	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family	NA|419aa|down_5|CP033581.1_2405221_2406478_-	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily	NA|258aa|down_6|CP033581.1_2406474_2407248_-	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]	NA|106aa|down_7|CP033581.1_2407255_2407573_-	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO)	NA|393aa|down_8|CP033581.1_2407572_2408751_-	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]	NA|472aa|down_9|CP033581.1_2408829_2410245_-	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	5	2439421-2439530	5	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GCCGGCGTTTGAGGCGCGGGTCGGGCA	27	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA,NA|115aa|down_0|CP033581.1_2439669_2440014_-	NA|96aa|up_9|CP033581.1_2426956_2427244_-	pfam13397, RbpA, RNA polymerase-binding protein	NA|79aa|up_8|CP033581.1_2427471_2427708_-	PRK06870, secG, preprotein translocase subunit SecG; Reviewed	NA|259aa|up_7|CP033581.1_2427823_2428600_-	PRK00042, tpiA, triosephosphate isomerase; Provisional	NA|404aa|up_6|CP033581.1_2428606_2429818_-	PRK00073, pgk, phosphoglycerate kinase; Provisional	NA|336aa|up_5|CP033581.1_2429956_2430964_-	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]	NA|991aa|up_4|CP033581.1_2431194_2434167_-	cd03859, M14_CPT, Peptidase M14 Carboxypeptidase T subfamily	NA|332aa|up_3|CP033581.1_2434318_2435314_-	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA	NA|352aa|up_2|CP033581.1_2435304_2436360_-	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related	NA|322aa|up_1|CP033581.1_2436356_2437322_-	PRK05416, PRK05416, RNase adapter RapZ	NA|670aa|up_0|CP033581.1_2437318_2439328_-	PRK00558, uvrC, excinuclease ABC subunit UvrC	NA|115aa|down_0|CP033581.1_2439669_2440014_-	NA	NA|197aa|down_1|CP033581.1_2440494_2441085_-	pfam12385, Peptidase_C70, Papain-like cysteine protease AvrRpt2	NA|313aa|down_2|CP033581.1_2441316_2442255_+	PRK13355, PRK13355, bifunctional HTH-domain containing protein/aminotransferase; Provisional	NA|144aa|down_3|CP033581.1_2442301_2442733_-	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes	NA|291aa|down_4|CP033581.1_2442807_2443680_+	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate	NA|463aa|down_5|CP033581.1_2443821_2445210_-	pfam01548, DEDD_Tnp_IS110, Transposase	NA|999aa|down_6|CP033581.1_2445528_2448525_-	PRK00349, uvrA, excinuclease ABC subunit UvrA	NA|230aa|down_7|CP033581.1_2448714_2449404_+	PRK09583, PRK09583, mycothiol-dependent maleylpyruvate isomerase; Reviewed	NA|219aa|down_8|CP033581.1_2449413_2450070_+	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|173aa|down_9|CP033581.1_2451028_2451547_+	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	6	2832949-2833024	6	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GCGCCTCAAACGCCGGCGAGGCT	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA,NA|368aa|down_5|CP033581.1_2839347_2840451_+	NA|433aa|up_9|CP033581.1_2823055_2824354_+	TIGR01412, Probable_deferrochelatase/peroxidase_EfeN, Tat-translocated enzyme	NA|285aa|up_8|CP033581.1_2824375_2825230_+	pfam03239, FTR1, Iron permease FTR1 family	NA|207aa|up_7|CP033581.1_2825303_2825924_-	COG2153, ElaA, Predicted acyltransferase [General function prediction only]	NA|287aa|up_6|CP033581.1_2825920_2826781_-	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only]	NA|254aa|up_5|CP033581.1_2826839_2827601_-	cd05233, SDR_c, classical (c) SDRs	NA|435aa|up_4|CP033581.1_2827707_2829012_+	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|340aa|up_3|CP033581.1_2829044_2830064_+	pfam09243, Rsm22, Mitochondrial small ribosomal subunit Rsm22	NA|270aa|up_2|CP033581.1_2830090_2830900_-	COG1834, COG1834, N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]	NA|247aa|up_1|CP033581.1_2831031_2831772_+	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|250aa|up_0|CP033581.1_2831947_2832697_+	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal	NA|267aa|down_0|CP033581.1_2833083_2833884_-	PRK02101, PRK02101, peroxide stress protein YaaA	NA|482aa|down_1|CP033581.1_2833987_2835433_+	COG0557, VacB, Exoribonuclease R [Transcription]	NA|455aa|down_2|CP033581.1_2835991_2837356_-	PRK07238, PRK07238, bifunctional RNase H/acid phosphatase; Provisional	NA|174aa|down_3|CP033581.1_2837355_2837877_-	COG1579, COG1579, Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]	NA|283aa|down_4|CP033581.1_2838114_2838963_-	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3)	NA|368aa|down_5|CP033581.1_2839347_2840451_+	NA	NA|314aa|down_6|CP033581.1_2840513_2841455_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|359aa|down_7|CP033581.1_2841469_2842546_-	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase	NA|285aa|down_8|CP033581.1_2842578_2843433_-	PLN02864, PLN02864, enoyl-CoA hydratase	NA|120aa|down_9|CP033581.1_2843666_2844026_+	cd19930, REC_DesR-like, phosphoacceptor receiver (REC) domain of DesR and similar proteins
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	7	2937910-2938013	7	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	TGCTCTGCCAATTGAGCTACAGGGGA	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|203aa|up_9|CP033581.1_2927480_2928089_+,NA|246aa|up_4|CP033581.1_2932236_2932974_+,NA|125aa|up_2|CP033581.1_2934483_2934858_+,NA|104aa|down_0|CP033581.1_2938159_2938471_+	NA|203aa|up_9|CP033581.1_2927480_2928089_+	NA	NA|241aa|up_8|CP033581.1_2928148_2928871_-	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]	NA|346aa|up_7|CP033581.1_2929092_2930130_+	pfam06723, MreB_Mbl, MreB/Mbl protein	NA|521aa|up_6|CP033581.1_2930126_2931689_+	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms]	NA|149aa|up_5|CP033581.1_2931719_2932166_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|246aa|up_4|CP033581.1_2932236_2932974_+	NA	NA|459aa|up_3|CP033581.1_2933022_2934399_+	COG0825, AccA, Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]	NA|125aa|up_2|CP033581.1_2934483_2934858_+	NA	NA|443aa|up_1|CP033581.1_2934882_2936211_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|382aa|up_0|CP033581.1_2936360_2937506_+	PRK13517, PRK13517, glutamate--cysteine ligase	NA|104aa|down_0|CP033581.1_2938159_2938471_+	NA	NA|495aa|down_1|CP033581.1_2938511_2939996_+	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|578aa|down_2|CP033581.1_2940144_2941878_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|634aa|down_3|CP033581.1_2941895_2943797_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|363aa|down_4|CP033581.1_2943892_2944981_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|236aa|down_5|CP033581.1_2945186_2945894_-	COG2949, SanA, Uncharacterized membrane protein [Function unknown]	NA|240aa|down_6|CP033581.1_2946254_2946974_+	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]	NA|446aa|down_7|CP033581.1_2947031_2948369_+	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|425aa|down_8|CP033581.1_2948462_2949737_+	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|636aa|down_9|CP033581.1_2949771_2951679_+	PRK05667, dnaG, DNA primase; Validated
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	8	3468589-3468688	8	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	TCCAGCCCCGCCGGCGTTTGAGGCGC	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|393aa|up_9|CP033581.1_3456622_3457801_-,NA|230aa|up_7|CP033581.1_3458870_3459560_-,NA|162aa|up_0|CP033581.1_3467863_3468349_+,NA|283aa|down_3|CP033581.1_3473137_3473986_+,NA|121aa|down_4|CP033581.1_3473969_3474332_-	NA|393aa|up_9|CP033581.1_3456622_3457801_-	NA	NA|352aa|up_8|CP033581.1_3457797_3458853_-	PRK11855, PRK11855, dihydrolipoamide acetyltransferase; Reviewed	NA|230aa|up_7|CP033581.1_3458870_3459560_-	NA	NA|393aa|up_6|CP033581.1_3459717_3460896_-	PRK14085, PRK14085, imidazolonepropionase; Provisional	NA|447aa|up_5|CP033581.1_3461070_3462411_-	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated	NA|410aa|up_4|CP033581.1_3462401_3463631_-	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed	NA|555aa|up_3|CP033581.1_3463627_3465292_-	PRK05414, PRK05414, urocanate hydratase; Provisional	NA|459aa|up_2|CP033581.1_3465396_3466773_+	cd06836, PLPDE_III_ODC_DapDC_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Uncharacterized Proteins with similarity to Ornithine and Diaminopimelate Decarboxylases	NA|281aa|up_1|CP033581.1_3466968_3467811_-	COG1737, RpiR, Transcriptional regulators [Transcription]	NA|162aa|up_0|CP033581.1_3467863_3468349_+	NA	NA|461aa|down_0|CP033581.1_3468953_3470336_-	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|373aa|down_1|CP033581.1_3470457_3471576_+	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|407aa|down_2|CP033581.1_3471627_3472848_+	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|283aa|down_3|CP033581.1_3473137_3473986_+	NA	NA|121aa|down_4|CP033581.1_3473969_3474332_-	NA	NA|77aa|down_5|CP033581.1_3474433_3474664_+	pfam14117, DUF4287, Domain of unknown function (DUF4287)	NA|288aa|down_6|CP033581.1_3474797_3475661_-	pfam12811, BaxI_1, Bax inhibitor 1 like	NA|258aa|down_7|CP033581.1_3476331_3477105_+	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]	NA|851aa|down_8|CP033581.1_3477160_3479713_+	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]	NA|444aa|down_9|CP033581.1_3479799_3481131_-	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	11	3723492-3723577	10	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	CCCGCCGGGGCAAATTCAGCCTCGCCGGCG	30	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|112aa|up_6|CP033581.1_3715765_3716101_-,NA|98aa|up_4|CP033581.1_3717137_3717431_-,NA|205aa|up_2|CP033581.1_3719377_3719992_+,NA|83aa|down_9|CP033581.1_3737998_3738247_+	NA|142aa|up_9|CP033581.1_3714138_3714564_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|279aa|up_8|CP033581.1_3714693_3715530_+	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|81aa|up_7|CP033581.1_3715526_3715769_+	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|112aa|up_6|CP033581.1_3715765_3716101_-	NA	NA|281aa|up_5|CP033581.1_3716179_3717022_-	pfam14023, DUF4239, Protein of unknown function (DUF4239)	NA|98aa|up_4|CP033581.1_3717137_3717431_-	NA	NA|520aa|up_3|CP033581.1_3717508_3719068_-	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|205aa|up_2|CP033581.1_3719377_3719992_+	NA	NA|503aa|up_1|CP033581.1_3720187_3721696_-	cd07089, ALDH_CddD-AldA-like, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like and related proteins	NA|580aa|up_0|CP033581.1_3721692_3723432_-	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics	NA|374aa|down_0|CP033581.1_3723932_3725054_-	COG2141, COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]	NA|263aa|down_1|CP033581.1_3725163_3725952_-	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|316aa|down_2|CP033581.1_3725969_3726917_-	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family	NA|270aa|down_3|CP033581.1_3727286_3728096_-	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|136aa|down_4|CP033581.1_3730194_3730602_+	cd04685, Nudix_Hydrolase_26, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|293aa|down_5|CP033581.1_3731197_3732076_-	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]	NA|380aa|down_6|CP033581.1_3732265_3733405_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|413aa|down_7|CP033581.1_3733411_3734650_-	pfam04909, Amidohydro_2, Amidohydrolase	NA|1006aa|down_8|CP033581.1_3734782_3737800_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|83aa|down_9|CP033581.1_3737998_3738247_+	NA
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	12	3729670-3729768	11	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	AGCCGAGAGGCAGGCGGGTAGCGATCGTGGG	31	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|98aa|up_8|CP033581.1_3717137_3717431_-,NA|205aa|up_6|CP033581.1_3719377_3719992_+,NA|83aa|down_5|CP033581.1_3737998_3738247_+	NA|281aa|up_9|CP033581.1_3716179_3717022_-	pfam14023, DUF4239, Protein of unknown function (DUF4239)	NA|98aa|up_8|CP033581.1_3717137_3717431_-	NA	NA|520aa|up_7|CP033581.1_3717508_3719068_-	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|205aa|up_6|CP033581.1_3719377_3719992_+	NA	NA|503aa|up_5|CP033581.1_3720187_3721696_-	cd07089, ALDH_CddD-AldA-like, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like and related proteins	NA|580aa|up_4|CP033581.1_3721692_3723432_-	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics	NA|374aa|up_3|CP033581.1_3723932_3725054_-	COG2141, COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]	NA|263aa|up_2|CP033581.1_3725163_3725952_-	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|316aa|up_1|CP033581.1_3725969_3726917_-	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family	NA|270aa|up_0|CP033581.1_3727286_3728096_-	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|136aa|down_0|CP033581.1_3730194_3730602_+	cd04685, Nudix_Hydrolase_26, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|293aa|down_1|CP033581.1_3731197_3732076_-	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]	NA|380aa|down_2|CP033581.1_3732265_3733405_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|413aa|down_3|CP033581.1_3733411_3734650_-	pfam04909, Amidohydro_2, Amidohydrolase	NA|1006aa|down_4|CP033581.1_3734782_3737800_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|83aa|down_5|CP033581.1_3737998_3738247_+	NA	NA|241aa|down_6|CP033581.1_3738437_3739160_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|537aa|down_7|CP033581.1_3739176_3740787_-	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated	NA|384aa|down_8|CP033581.1_3740873_3742025_+	PRK07855, PRK07855, lipid-transfer protein; Provisional	NA|149aa|down_9|CP033581.1_3742038_3742485_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	14	4033491-4033927	2	CRT	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	CCACGGTCGCCACCACGGTCGTCACG	26	0	0	NA	NA	NA	5	5	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA,NA|285aa|down_9|CP033581.1_4045979_4046834_-	NA|257aa|up_9|CP033581.1_4015498_4016269_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|685aa|up_8|CP033581.1_4016560_4018615_+	pfam08305, NPCBM, NPCBM/NEW2 domain	NA|1082aa|up_7|CP033581.1_4018601_4021847_-	COG3903, COG3903, Predicted ATPase [General function prediction only]	NA|740aa|up_6|CP033581.1_4022030_4024250_-	COG0367, AsnB, Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]	NA|523aa|up_5|CP033581.1_4024937_4026506_+	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional	NA|403aa|up_4|CP033581.1_4026565_4027774_+	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase	NA|269aa|up_3|CP033581.1_4027867_4028674_+	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed	NA|442aa|up_2|CP033581.1_4028760_4030086_+	pfam13367, PrsW-protease, Protease prsW family	NA|359aa|up_1|CP033581.1_4029994_4031071_-	pfam01551, Peptidase_M23, Peptidase family M23	NA|387aa|up_0|CP033581.1_4031372_4032533_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|197aa|down_0|CP033581.1_4035852_4036443_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|125aa|down_1|CP033581.1_4036525_4036900_-	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]	NA|181aa|down_2|CP033581.1_4036896_4037439_-	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB)	NA|117aa|down_3|CP033581.1_4037435_4037786_-	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein	NA|281aa|down_4|CP033581.1_4038243_4039086_-	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]	NA|247aa|down_5|CP033581.1_4039082_4039823_-	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti	NA|165aa|down_6|CP033581.1_4039876_4040371_-	PRK12678, PRK12678, transcription termination factor Rho; Provisional	NA|1311aa|down_7|CP033581.1_4040478_4044411_+	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional	NA|69aa|down_8|CP033581.1_4045183_4045390_-	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins	NA|285aa|down_9|CP033581.1_4045979_4046834_-	NA
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	15	4210708-4210791	13	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GGGGCGATGTTTCACGTGAAACATCG	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|102aa|up_6|CP033581.1_4200444_4200750_+,NA|754aa|down_1|CP033581.1_4212467_4214729_+,NA|320aa|down_4|CP033581.1_4219522_4220482_+	NA|79aa|up_9|CP033581.1_4198950_4199187_-	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed	NA|200aa|up_8|CP033581.1_4199230_4199830_-	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional	NA|97aa|up_7|CP033581.1_4199902_4200193_-	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed	NA|102aa|up_6|CP033581.1_4200444_4200750_+	NA	NA|373aa|up_5|CP033581.1_4200889_4202008_+	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis]	NA|344aa|up_4|CP033581.1_4202086_4203118_+	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase	NA|493aa|up_3|CP033581.1_4203154_4204633_-	COG5650, COG5650, Predicted integral membrane protein [Function unknown]	NA|874aa|up_2|CP033581.1_4204719_4207341_-	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]	NA|201aa|up_1|CP033581.1_4207615_4208218_+	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|361aa|up_0|CP033581.1_4208268_4209351_+	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type	NA|481aa|down_0|CP033581.1_4210840_4212283_-	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase	NA|754aa|down_1|CP033581.1_4212467_4214729_+	NA	NA|573aa|down_2|CP033581.1_4217070_4218789_+	cd13973, PK_MviN-like, Pseudokinase domain of the peptidoglycan biosynthetic protein MviN	NA|238aa|down_3|CP033581.1_4218812_4219526_+	PRK09643, PRK09643, RNA polymerase sigma factor SigM; Reviewed	NA|320aa|down_4|CP033581.1_4219522_4220482_+	NA	NA|320aa|down_5|CP033581.1_4220606_4221566_+	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase	NA|114aa|down_6|CP033581.1_4221615_4221957_+	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin	NA|206aa|down_7|CP033581.1_4222026_4222644_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|365aa|down_8|CP033581.1_4222752_4223847_-	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein	NA|349aa|down_9|CP033581.1_4223839_4224886_-	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	19	4979059-4979178	16	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	CCCCCGGTCCTCAATCGCCGGACGGGCTGG	30	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|515aa|up_8|CP033581.1_4964887_4966432_-,NA|386aa|up_7|CP033581.1_4966679_4967837_-,NA|749aa|up_5|CP033581.1_4969257_4971504_+,NA|202aa|down_0|CP033581.1_4979588_4980194_-	NA|134aa|up_9|CP033581.1_4964028_4964430_+	cd02071, MM_CoA_mut_B12_BD, methylmalonyl CoA mutase B12 binding domain	NA|515aa|up_8|CP033581.1_4964887_4966432_-	NA	NA|386aa|up_7|CP033581.1_4966679_4967837_-	NA	NA|369aa|up_6|CP033581.1_4968154_4969261_+	pfam07728, AAA_5, AAA domain (dynein-related subfamily)	NA|749aa|up_5|CP033581.1_4969257_4971504_+	NA	NA|395aa|up_4|CP033581.1_4971606_4972791_+	pfam05762, VWA_CoxE, VWA domain containing CoxE-like protein	NA|393aa|up_3|CP033581.1_4973043_4974222_+	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta	NA|297aa|up_2|CP033581.1_4974243_4975134_+	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated	NA|681aa|up_1|CP033581.1_4975235_4977278_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|501aa|up_0|CP033581.1_4977499_4979002_+	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau	NA|202aa|down_0|CP033581.1_4979588_4980194_-	NA	NA|208aa|down_1|CP033581.1_4980425_4981049_+	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed	NA|531aa|down_2|CP033581.1_4981045_4982638_+	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional	NA|226aa|down_3|CP033581.1_4982719_4983397_-	pfam09849, DUF2076, Uncharacterized protein conserved in bacteria (DUF2076)	NA|289aa|down_4|CP033581.1_4983643_4984510_+	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional	NA|231aa|down_5|CP033581.1_4984499_4985192_+	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|330aa|down_6|CP033581.1_4985384_4986374_+	PRK05442, PRK05442, malate dehydrogenase; Provisional	NA|575aa|down_7|CP033581.1_4986475_4988200_+	cd17330, MFS_SLC46_TetA_like, Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters	NA|140aa|down_8|CP033581.1_4988183_4988603_+	pfam11896, DUF3416, Domain of unknown function (DUF3416)	NA|344aa|down_9|CP033581.1_4988606_4989638_+	PHA03247, PHA03247, large tegument protein UL36; Provisional
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	20	5105898-5105990	17	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	GTGGCTGGACACAAGCCGCCCACGA	25	1	1	5105923-5105965	CP033581.1_1958054-1958096	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|75aa|up_8|CP033581.1_5093373_5093598_+,NA|144aa|up_3|CP033581.1_5102490_5102922_+,NA|134aa|up_2|CP033581.1_5103113_5103515_-,NA|82aa|up_0|CP033581.1_5105243_5105489_+,NA|156aa|down_1|CP033581.1_5107554_5108022_-,NA|136aa|down_2|CP033581.1_5108160_5108568_-,NA|62aa|down_3|CP033581.1_5108768_5108954_-	NA|287aa|up_9|CP033581.1_5092510_5093371_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|75aa|up_8|CP033581.1_5093373_5093598_+	NA	NA|1077aa|up_7|CP033581.1_5093741_5096972_-	sd00006, TPR, Tetratricopeptide repeat	NA|688aa|up_6|CP033581.1_5097371_5099435_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|227aa|up_5|CP033581.1_5099492_5100173_-	pfam03006, HlyIII, Haemolysin-III related	NA|613aa|up_4|CP033581.1_5100384_5102223_+	PRK04210, PRK04210, phosphoenolpyruvate carboxykinase (GTP)	NA|144aa|up_3|CP033581.1_5102490_5102922_+	NA	NA|134aa|up_2|CP033581.1_5103113_5103515_-	NA	NA|404aa|up_1|CP033581.1_5103620_5104832_-	PRK09265, PRK09265, aminotransferase AlaT; Validated	NA|82aa|up_0|CP033581.1_5105243_5105489_+	NA	NA|159aa|down_0|CP033581.1_5107085_5107562_+	cd02901, Macro_Poa1p-like, macrodomain, Poa1p-like family	NA|156aa|down_1|CP033581.1_5107554_5108022_-	NA	NA|136aa|down_2|CP033581.1_5108160_5108568_-	NA	NA|62aa|down_3|CP033581.1_5108768_5108954_-	NA	NA|339aa|down_4|CP033581.1_5109037_5110054_-	cd06259, YdcF-like, YdcF-like	NA|529aa|down_5|CP033581.1_5110076_5111663_-	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics	NA|427aa|down_6|CP033581.1_5111671_5112952_-	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase	NA|255aa|down_7|CP033581.1_5113108_5113873_+	COG1414, IclR, Transcriptional regulator [Transcription]	NA|137aa|down_8|CP033581.1_5113869_5114280_+	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function	NA|446aa|down_9|CP033581.1_5114362_5115700_-	cd03859, M14_CPT, Peptidase M14 Carboxypeptidase T subfamily
GCA_003721495.1_ASM372149v1	CP033581	Streptomyces sp. ADI95-16 chromosome, complete genome	23	7427950-7428040	20	CRISPRCasFinder	no		WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT	Orphan	TCAGGGAACGGCGGCCGGGCGTCAGG	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA,NA|202aa|down_3|CP033581.1_7431300_7431906_-,NA|167aa|down_5|CP033581.1_7434429_7434930_-	NA|306aa|up_9|CP033581.1_7415701_7416619_-	COG1737, RpiR, Transcriptional regulators [Transcription]	NA|276aa|up_8|CP033581.1_7416841_7417669_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|293aa|up_7|CP033581.1_7417789_7418668_+	pfam05231, MASE1, MASE1	NA|283aa|up_6|CP033581.1_7418806_7419655_+	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|226aa|up_5|CP033581.1_7419801_7420479_+	cd01624, HAD_VSP_like, vegetative storage proteins and related proteins, similar to soybean VSPalpha and VSPbeta proteins; belongs to the haloacid dehalogenase-like superfamily	NA|682aa|up_4|CP033581.1_7420554_7422600_-	pfam02128, Peptidase_M36, Fungalysin metallopeptidase (M36)	NA|642aa|up_3|CP033581.1_7422629_7424555_-	pfam04389, Peptidase_M28, Peptidase family M28	NA|293aa|up_2|CP033581.1_7424860_7425739_+	cd06583, PGRP, Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls	NA|543aa|up_1|CP033581.1_7425870_7427499_+	PRK08315, PRK08315, AMP-binding domain protein; Validated	NA|109aa|up_0|CP033581.1_7427512_7427839_-	COG1359, COG1359, Uncharacterized conserved protein [Function unknown]	NA|246aa|down_0|CP033581.1_7428055_7428793_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|320aa|down_1|CP033581.1_7429006_7429966_-	pfam04909, Amidohydro_2, Amidohydrolase	NA|417aa|down_2|CP033581.1_7430036_7431287_-	pfam01391, Collagen, Collagen triple helix repeat (20 copies)	NA|202aa|down_3|CP033581.1_7431300_7431906_-	NA	NA|693aa|down_4|CP033581.1_7432258_7434337_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|167aa|down_5|CP033581.1_7434429_7434930_-	NA	NA|370aa|down_6|CP033581.1_7435051_7436161_-	pfam05935, Arylsulfotrans, Arylsulfotransferase (ASST)	NA|364aa|down_7|CP033581.1_7436245_7437337_-	cd01008, PBP2_NrtA_SsuA_CpmA_like, Substrate binding domain of ABC-type nitrate/sulfonate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily	NA|250aa|down_8|CP033581.1_7437333_7438083_-	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters	NA|267aa|down_9|CP033581.1_7438079_7438880_-	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]
GCA_003721495.1_ASM372149v1	CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	2	566244-566386	1	CRISPRCasFinder	no		DEDDh	Orphan	CCGCCGACGCGGGGGTGTTCCGG	23	0	0	NA	NA	NA	2	2	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|247aa|up_9|CP033582.1_560101_560842_-,NA|155aa|up_8|CP033582.1_560889_561354_+,NA|208aa|up_7|CP033582.1_561410_562034_-,NA|76aa|up_6|CP033582.1_562107_562335_-,NA|125aa|up_5|CP033582.1_562452_562827_-,NA|204aa|up_4|CP033582.1_563060_563672_-,NA|183aa|up_3|CP033582.1_563788_564337_-,NA|49aa|up_2|CP033582.1_564431_564578_-,NA|51aa|up_1|CP033582.1_564678_564831_-,NA|423aa|up_0|CP033582.1_564889_566158_-,NA|76aa|down_4|CP033582.1_573892_574120_-,NA|145aa|down_9|CP033582.1_577453_577888_+	NA|247aa|up_9|CP033582.1_560101_560842_-	NA	NA|155aa|up_8|CP033582.1_560889_561354_+	NA	NA|208aa|up_7|CP033582.1_561410_562034_-	NA	NA|76aa|up_6|CP033582.1_562107_562335_-	NA	NA|125aa|up_5|CP033582.1_562452_562827_-	NA	NA|204aa|up_4|CP033582.1_563060_563672_-	NA	NA|183aa|up_3|CP033582.1_563788_564337_-	NA	NA|49aa|up_2|CP033582.1_564431_564578_-	NA	NA|51aa|up_1|CP033582.1_564678_564831_-	NA	NA|423aa|up_0|CP033582.1_564889_566158_-	NA	NA|431aa|down_0|CP033582.1_566575_567868_-	pfam00872, Transposase_mut, Transposase, Mutator family	NA|513aa|down_1|CP033582.1_568113_569652_+	COG4469, CoiA, Competence protein CoiA-like family, contains a predicted nuclease    domain [General function prediction only]	NA|573aa|down_2|CP033582.1_570448_572167_+	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases	NA|498aa|down_3|CP033582.1_572367_573861_+	pfam00872, Transposase_mut, Transposase, Mutator family	NA|76aa|down_4|CP033582.1_573892_574120_-	NA	NA|396aa|down_5|CP033582.1_574355_575543_+	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin	NA|183aa|down_6|CP033582.1_575857_576406_-	pfam00932, LTD, Lamin Tail Domain	NA|75aa|down_7|CP033582.1_576488_576713_-	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain	NA|77aa|down_8|CP033582.1_576749_576980_-	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain	NA|145aa|down_9|CP033582.1_577453_577888_+	NA
GCA_003721495.1_ASM372149v1	CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	3	581188-581335	1,2	PILER-CR,CRISPRCasFinder	no		DEDDh	Orphan	CTGCTCCCCGCGCA---------------------------------CGCGGGGATGGCCCCA,CATCCCCGCGTGCGCGGGGAGCAG	63,24	0	0	NA	NA	NA:I-E	2,2	2	Orphan	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|76aa|up_9|CP033582.1_573892_574120_-,NA|145aa|up_4|CP033582.1_577453_577888_+,NA|142aa|up_3|CP033582.1_577995_578421_+,NA|418aa|up_1|CP033582.1_579237_580491_+,NA|192aa|up_0|CP033582.1_580487_581063_+,NA|81aa|down_0|CP033582.1_581848_582091_+,NA|168aa|down_1|CP033582.1_583243_583747_+,NA|167aa|down_2|CP033582.1_584166_584667_-,NA|207aa|down_3|CP033582.1_584983_585604_-,NA|102aa|down_5|CP033582.1_586086_586392_+,NA|51aa|down_6|CP033582.1_586313_586466_-,NA|374aa|down_7|CP033582.1_586951_588073_-,NA|109aa|down_9|CP033582.1_589952_590279_+	NA|76aa|up_9|CP033582.1_573892_574120_-	NA	NA|396aa|up_8|CP033582.1_574355_575543_+	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin	NA|183aa|up_7|CP033582.1_575857_576406_-	pfam00932, LTD, Lamin Tail Domain	NA|75aa|up_6|CP033582.1_576488_576713_-	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain	NA|77aa|up_5|CP033582.1_576749_576980_-	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain	NA|145aa|up_4|CP033582.1_577453_577888_+	NA	NA|142aa|up_3|CP033582.1_577995_578421_+	NA	NA|249aa|up_2|CP033582.1_578494_579241_+	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component	NA|418aa|up_1|CP033582.1_579237_580491_+	NA	NA|192aa|up_0|CP033582.1_580487_581063_+	NA	NA|81aa|down_0|CP033582.1_581848_582091_+	NA	NA|168aa|down_1|CP033582.1_583243_583747_+	NA	NA|167aa|down_2|CP033582.1_584166_584667_-	NA	NA|207aa|down_3|CP033582.1_584983_585604_-	NA	NA|85aa|down_4|CP033582.1_585687_585942_+	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system	NA|102aa|down_5|CP033582.1_586086_586392_+	NA	NA|51aa|down_6|CP033582.1_586313_586466_-	NA	NA|374aa|down_7|CP033582.1_586951_588073_-	NA	NA|510aa|down_8|CP033582.1_588390_589920_-	TIGR00665, DnaB, replicative DNA helicase	NA|109aa|down_9|CP033582.1_589952_590279_+	NA
GCA_003721495.1_ASM372149v1	CP033583	Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence	1	55871-61936	1,1,1,2,3,4,5	CRISPRCasFinder,CRT,PILER-CR,PILER-CR,PILER-CR,PILER-CR,PILER-CR	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	RT,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	Type I-E	CGGTCCACCCCCGCGTCGGCGGGGAGCAC,CACCCCCGCGTCGGCGGGGAGCAC,CTCCCCGCCGA---------------------------------CGCGGGGGTGAACCG,GTGCTCCCCGCCGA---------------------------------CGCGGGG,GTGCTCCCCGCCGA---------------------------------CGCGGGGGTGAACCG,GTGCTCCCCGCCGA---------------------------------CGCGGGGGTGGACC,GTGCTCCCCGCCGA---------------------------------CGCGGGGGTGGACCG	29,24,59,54,62,61,62	2	8	61571-61602|61571-61602|61571-61602|61571-61602|61571-61602|61571-61602|61571-61602|61632-61663	CP033581.1_1827562-1827531|CP033581.1_2308915-2308884|CP033581.1_3404085-3404054|CP033581.1_4000373-4000342|CP033581.1_4009150-4009119|CP033581.1_4692699-4692730|CP033581.1_5918237-5918268|CP033583.1_40330-40361	NA:NA:NA:NA:NA:NA:NA	99,99,86,86,86,86,86	99	TypeI-E	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA|56aa|up_6|CP033583.1_49001_49169_-,NA|348aa|up_5|CP033583.1_49289_50333_+,NA	NA|283aa|up_9|CP033583.1_46148_46997_-	PTZ00121, PTZ00121, MAEBL; Provisional	NA|253aa|up_8|CP033583.1_47331_48090_+	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|229aa|up_7|CP033583.1_48086_48773_+	pfam13671, AAA_33, AAA domain	NA|56aa|up_6|CP033583.1_49001_49169_-	NA	NA|348aa|up_5|CP033583.1_49289_50333_+	NA	NA|227aa|up_4|CP033583.1_50334_51015_+	PRK05625, PRK05625, 5-amino-6-(5-phosphoribosylamino)uracil reductase; Validated	NA|157aa|up_3|CP033583.1_51014_51485_+	cd01284, Riboflavin_deaminase-reductase, Riboflavin-specific deaminase	NA|89aa|up_2|CP033583.1_51911_52178_+	pfam01381, HTH_3, Helix-turn-helix	NA|668aa|up_1|CP033583.1_53035_55039_+	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|270aa|up_0|CP033583.1_55035_55845_+	PRK03195, PRK03195, DUF721 family protein	cas3|963aa|down_0|CP033583.1_62104_64993_+	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	cas8e|539aa|down_1|CP033583.1_65284_66901_+	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	cse2gr11|243aa|down_2|CP033583.1_66897_67626_+	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas7|377aa|down_3|CP033583.1_67622_68753_+	pfam09344, Cas_CT1975, CT1975-like protein	cas5|270aa|down_4|CP033583.1_68749_69559_+	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas6e|217aa|down_5|CP033583.1_69555_70206_+	pfam08798, CRISPR_assoc, CRISPR associated protein	cas1|310aa|down_6|CP033583.1_70262_71192_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	NA|106aa|down_7|CP033583.1_73460_73778_+	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|291aa|down_8|CP033583.1_73774_74647_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|462aa|down_9|CP033583.1_74741_76127_+	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases
GCA_003721495.1_ASM372149v1	CP033583	Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence	2	71538-73213	2,2	CRISPRCasFinder,CRT	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	RT,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	Type I-E	GTGCTCCCCGCCGACGCGGGGGTGAACCG,GTGCTCCCCGCCGACGCGGGGGTGAACCG	29,29	0	0	NA	NA	NA:NA	27,27	27	TypeI-E	WYL,csa3,PrimPol,DEDDh,cas4,cas3,DinG,RT,cas8e,cse2gr11,cas7,cas5,cas6e,cas1	NA,NA|84aa|down_3|CP033583.1_76291_76543_+,NA|53aa|down_5|CP033583.1_76847_77006_+,NA|97aa|down_7|CP033583.1_77386_77677_+,NA|82aa|down_8|CP033583.1_77683_77929_-	NA|89aa|up_9|CP033583.1_51911_52178_+	pfam01381, HTH_3, Helix-turn-helix	NA|668aa|up_8|CP033583.1_53035_55039_+	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|270aa|up_7|CP033583.1_55035_55845_+	PRK03195, PRK03195, DUF721 family protein	cas3|963aa|up_6|CP033583.1_62104_64993_+	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	cas8e|539aa|up_5|CP033583.1_65284_66901_+	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	cse2gr11|243aa|up_4|CP033583.1_66897_67626_+	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas7|377aa|up_3|CP033583.1_67622_68753_+	pfam09344, Cas_CT1975, CT1975-like protein	cas5|270aa|up_2|CP033583.1_68749_69559_+	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas6e|217aa|up_1|CP033583.1_69555_70206_+	pfam08798, CRISPR_assoc, CRISPR associated protein	cas1|310aa|up_0|CP033583.1_70262_71192_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	NA|106aa|down_0|CP033583.1_73460_73778_+	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|291aa|down_1|CP033583.1_73774_74647_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|462aa|down_2|CP033583.1_74741_76127_+	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases	NA|84aa|down_3|CP033583.1_76291_76543_+	NA	NA|86aa|down_4|CP033583.1_76539_76797_+	pfam01527, HTH_Tnp_1, Transposase	NA|53aa|down_5|CP033583.1_76847_77006_+	NA	NA|115aa|down_6|CP033583.1_76992_77337_-	PRK06526, PRK06526, transposase; Provisional	NA|97aa|down_7|CP033583.1_77386_77677_+	NA	NA|82aa|down_8|CP033583.1_77683_77929_-	NA	NA|466aa|down_9|CP033583.1_78450_79848_-	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional
