assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003074055.1_ASM307405v1	CP029043	Streptomyces nigra strain 452 chromosome, complete genome	2	2299155-2299241	2	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	Orphan	TGGCTCTGCTCACGGCGGTCGGC	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	NA,NA|72aa|down_5|CP029043.1_2307059_2307275_+	NA|404aa|up_9|CP029043.1_2283144_2284356_+	COG1251, NirB, NAD(P)H-nitrite reductase [Energy production and conversion]	NA|871aa|up_8|CP029043.1_2284355_2286968_+	PRK14989, PRK14989, nitrite reductase subunit NirD; Provisional	NA|117aa|up_7|CP029043.1_2286964_2287315_+	pfam13806, Rieske_2, Rieske-like [2Fe-2S] domain	NA|323aa|up_6|CP029043.1_2287389_2288358_-	PRK06197, PRK06197, short chain dehydrogenase; Provisional	NA|150aa|up_5|CP029043.1_2288434_2288884_-	pfam05901, Excalibur, Excalibur calcium-binding domain	NA|386aa|up_4|CP029043.1_2289274_2290432_+	pfam05787, DUF839, Bacterial protein of unknown function (DUF839)	NA|98aa|up_3|CP029043.1_2290752_2291046_-	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain	NA|907aa|up_2|CP029043.1_2291316_2294037_-	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional	NA|399aa|up_1|CP029043.1_2294488_2295685_-	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|481aa|up_0|CP029043.1_2295806_2297249_+	PRK10137, PRK10137, alpha-glucosidase; Provisional	NA|589aa|down_0|CP029043.1_2299392_2301159_+	cd16015, LTA_synthase, Lipoteichoic acid synthase like	NA|381aa|down_1|CP029043.1_2301173_2302316_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|482aa|down_2|CP029043.1_2302405_2303851_+	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|236aa|down_3|CP029043.1_2303993_2304701_+	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|756aa|down_4|CP029043.1_2304697_2306965_+	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|72aa|down_5|CP029043.1_2307059_2307275_+	NA	NA|208aa|down_6|CP029043.1_2307271_2307895_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|200aa|down_7|CP029043.1_2307899_2308499_-	pfam17935, TetR_C_27, Tetracyclin repressor-like, C-terminal domain	NA|336aa|down_8|CP029043.1_2308540_2309548_-	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR)	NA|349aa|down_9|CP029043.1_2309710_2310757_+	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD)
GCA_003074055.1_ASM307405v1	CP029043	Streptomyces nigra strain 452 chromosome, complete genome	3	2724328-2724395	3	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	Orphan	TCGGATCCGGCGGTCTCAGATCCG	24	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	NA|188aa|up_0|CP029043.1_2723659_2724223_-,NA|275aa|down_1|CP029043.1_2726371_2727196_-,NA|104aa|down_7|CP029043.1_2731975_2732287_-	NA|253aa|up_9|CP029043.1_2712020_2712779_+	COG1414, IclR, Transcriptional regulator [Transcription]	NA|168aa|up_8|CP029043.1_2713178_2713682_-	PRK14326, PRK14326, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional	NA|202aa|up_7|CP029043.1_2713777_2714383_-	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading	NA|377aa|up_6|CP029043.1_2714502_2715633_-	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily	NA|476aa|up_5|CP029043.1_2715726_2717154_-	pfam01471, PG_binding_1, Putative peptidoglycan binding domain	NA|667aa|up_4|CP029043.1_2717875_2719876_+	cd06421, CESA_CelA_like, CESA_CelA_like are involved in the elongation of the glucan chain of cellulose	NA|646aa|up_3|CP029043.1_2719872_2721810_+	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase	NA|344aa|up_2|CP029043.1_2721879_2722911_-	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6	NA|223aa|up_1|CP029043.1_2722988_2723657_-	cd05829, Sortase_F, Sortase domain found in the class F family of sortases	NA|188aa|up_0|CP029043.1_2723659_2724223_-	NA	NA|260aa|down_0|CP029043.1_2724416_2725196_-	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase	NA|275aa|down_1|CP029043.1_2726371_2727196_-	NA	NA|373aa|down_2|CP029043.1_2727325_2728444_-	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|358aa|down_3|CP029043.1_2728492_2729566_+	PRK11579, PRK11579, putative oxidoreductase; Provisional	NA|169aa|down_4|CP029043.1_2729562_2730069_+	PRK02487, PRK02487, heme-degrading domain-containing protein	NA|286aa|down_5|CP029043.1_2730115_2730973_-	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]	NA|241aa|down_6|CP029043.1_2731133_2731856_-	pfam02096, 60KD_IMP, 60Kd inner membrane protein	NA|104aa|down_7|CP029043.1_2731975_2732287_-	NA	NA|176aa|down_8|CP029043.1_2732391_2732919_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|474aa|down_9|CP029043.1_2732987_2734409_+	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily
GCA_003074055.1_ASM307405v1	CP029043	Streptomyces nigra strain 452 chromosome, complete genome	6	4395062-4395146	5	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	Orphan	GTCCCCGCACCCCACCACGTGAGC	24	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	NA,NA|492aa|down_5|CP029043.1_4400094_4401570_-,NA|84aa|down_9|CP029043.1_4403777_4404029_+	NA|219aa|up_9|CP029043.1_4383023_4383680_+	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB	NA|323aa|up_8|CP029043.1_4385087_4386056_+	pfam00146, NADHdh, NADH dehydrogenase	NA|188aa|up_7|CP029043.1_4386058_4386622_+	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI	NA|234aa|up_6|CP029043.1_4386654_4387356_+	pfam00499, Oxidored_q3, NADH-ubiquinone/plastoquinone oxidoreductase chain 6	NA|127aa|up_5|CP029043.1_4387355_4387736_+	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK	NA|665aa|up_4|CP029043.1_4387732_4389727_+	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed	NA|525aa|up_3|CP029043.1_4389733_4391308_+	TIGR01972, NADH-quinone_oxidoreductase_subunit_M, proton-translocating NADH-quinone oxidoreductase, chain M	NA|508aa|up_2|CP029043.1_4391304_4392828_+	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN	NA|287aa|up_1|CP029043.1_4393068_4393929_+	PRK03072, PRK03072, heat shock protein HtpX; Provisional	NA|132aa|up_0|CP029043.1_4393925_4394321_+	PRK11770, PRK11770, YccF domain-containing protein	NA|422aa|down_0|CP029043.1_4395213_4396479_-	TIGR00909, putative_amino_acid_transporter, amino acid transporter	NA|89aa|down_1|CP029043.1_4396627_4396894_+	PRK10457, PRK10457, hypothetical protein; Provisional	NA|163aa|down_2|CP029043.1_4397051_4397540_-	cd11740, YajQ_like, Proteins similar to Escherichia coli YajQ	NA|457aa|down_3|CP029043.1_4398022_4399393_-	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|63aa|down_4|CP029043.1_4399452_4399641_-	COG3311, AlpA, Predicted transcriptional regulator [Transcription]	NA|492aa|down_5|CP029043.1_4400094_4401570_-	NA	NA|276aa|down_6|CP029043.1_4401572_4402400_-	smart00943, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal	NA|248aa|down_7|CP029043.1_4402396_4403140_-	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair]	NA|102aa|down_8|CP029043.1_4403229_4403535_-	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins	NA|84aa|down_9|CP029043.1_4403777_4404029_+	NA
GCA_003074055.1_ASM307405v1	CP029043	Streptomyces nigra strain 452 chromosome, complete genome	7	4507192-4507268	6	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	Orphan	GACCTGTGCCGTCCGCCTGAAGCG	24	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	NA,NA|61aa|down_0|CP029043.1_4507398_4507581_+,NA|187aa|down_1|CP029043.1_4507590_4508151_-,NA|93aa|down_5|CP029043.1_4510547_4510826_+	NA|313aa|up_9|CP029043.1_4496784_4497723_-	TIGR00271, Uncharacterized_protein_MJ0678, uncharacterized hydrophobic domain	NA|330aa|up_8|CP029043.1_4497739_4498729_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|616aa|up_7|CP029043.1_4498894_4500742_+	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|128aa|up_6|CP029043.1_4500793_4501177_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|479aa|up_5|CP029043.1_4501203_4502640_-	cd01171, YXKO-related, B	NA|124aa|up_4|CP029043.1_4502682_4503054_-	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional	NA|283aa|up_3|CP029043.1_4503178_4504027_+	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD	NA|389aa|up_2|CP029043.1_4504088_4505255_+	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase	NA|415aa|up_1|CP029043.1_4505435_4506680_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|171aa|up_0|CP029043.1_4506645_4507158_+	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE	NA|61aa|down_0|CP029043.1_4507398_4507581_+	NA	NA|187aa|down_1|CP029043.1_4507590_4508151_-	NA	NA|219aa|down_2|CP029043.1_4508253_4508910_+	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ	NA|166aa|down_3|CP029043.1_4508960_4509458_+	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase	NA|367aa|down_4|CP029043.1_4509450_4510551_+	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	NA|93aa|down_5|CP029043.1_4510547_4510826_+	NA	NA|353aa|down_6|CP029043.1_4510973_4512032_+	cd06296, PBP1_CatR-like, ligand-binding domain of a LacI-like transcriptional regulator, CatR which is involved in catechol degradation	NA|351aa|down_7|CP029043.1_4512145_4513198_+	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|119aa|down_8|CP029043.1_4513307_4513664_+	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown]	NA|409aa|down_9|CP029043.1_4514071_4515298_+	COG4941, COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription]
GCA_003074055.1_ASM307405v1	CP029043	Streptomyces nigra strain 452 chromosome, complete genome	8	4898830-4898949	7	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	Orphan	CCGGCACTCCCCCAAGCTCTTCGAGCAGGGGG	32	1	21	4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917|4898862-4898917	CP029043.1_3453743-3453688|CP029043.1_3776916-3776861|CP029043.1_4211536-4211591|CP029043.1_4884460-4884515|CP029043.1_6079155-6079100|CP029043.1_6501094-6501149|CP029043.1_6731286-6731341|CP029043.1_406055-406000|CP029043.1_417185-417130|CP029043.1_5607068-5607123|CP029043.1_6218501-6218556|CP029043.1_6836500-6836555|CP029043.1_25027-24972|CP029043.1_316785-316730|CP029043.1_494192-494137|CP029043.1_1326513-1326458|CP029043.1_1849397-1849342|CP029043.1_2027954-2027899|CP029043.1_4515375-4515320|CP029043.1_6123964-6124019|CP029043.1_7314164-7314109	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	NA|251aa|up_4|CP029043.1_4893909_4894662_+,NA|250aa|up_0|CP029043.1_4898033_4898783_+,NA|170aa|down_0|CP029043.1_4899021_4899531_-,NA|214aa|down_4|CP029043.1_4903189_4903831_+,NA|51aa|down_7|CP029043.1_4905605_4905758_-	NA|56aa|up_9|CP029043.1_4887770_4887938_+	pfam11314, DUF3117, Protein of unknown function (DUF3117)	NA|211aa|up_8|CP029043.1_4888031_4888664_-	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only]	NA|233aa|up_7|CP029043.1_4888965_4889664_+	PRK09647, PRK09647, RNA polymerase sigma factor SigE; Reviewed	NA|322aa|up_6|CP029043.1_4889660_4890626_+	pfam13490, zf-HC2, Putative zinc-finger	NA|144aa|up_5|CP029043.1_4893335_4893767_+	PRK01371, PRK01371, Sec-independent protein translocase protein TatB	NA|251aa|up_4|CP029043.1_4893909_4894662_+	NA	NA|378aa|up_3|CP029043.1_4894742_4895876_-	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase	NA|199aa|up_2|CP029043.1_4895919_4896516_-	pfam06210, DUF1003, Protein of unknown function (DUF1003)	NA|432aa|up_1|CP029043.1_4896505_4897801_-	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]	NA|250aa|up_0|CP029043.1_4898033_4898783_+	NA	NA|170aa|down_0|CP029043.1_4899021_4899531_-	NA	NA|372aa|down_1|CP029043.1_4899563_4900679_-	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily	NA|195aa|down_2|CP029043.1_4901182_4901767_+	pfam05076, SUFU, Suppressor of fused protein (SUFU)	NA|409aa|down_3|CP029043.1_4901797_4903024_-	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily	NA|214aa|down_4|CP029043.1_4903189_4903831_+	NA	NA|286aa|down_5|CP029043.1_4903944_4904802_+	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]	NA|202aa|down_6|CP029043.1_4904915_4905521_+	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion]	NA|51aa|down_7|CP029043.1_4905605_4905758_-	NA	NA|298aa|down_8|CP029043.1_4905997_4906891_+	COG1432, COG1432, Uncharacterized conserved protein [Function unknown]	NA|294aa|down_9|CP029043.1_4906887_4907769_-	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]
GCA_003074055.1_ASM307405v1	CP029043	Streptomyces nigra strain 452 chromosome, complete genome	9	4918984-4919072	8	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	Orphan	CGGAGGGGGCGCGATGAGCGGCGC	24	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,Cas9_archaeal,cas3,DinG	NA|127aa|up_6|CP029043.1_4910089_4910470_+,NA|90aa|up_4|CP029043.1_4911419_4911689_-,NA|75aa|up_1|CP029043.1_4913179_4913404_-,NA	NA|298aa|up_9|CP029043.1_4905997_4906891_+	COG1432, COG1432, Uncharacterized conserved protein [Function unknown]	NA|294aa|up_8|CP029043.1_4906887_4907769_-	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|757aa|up_7|CP029043.1_4907877_4910148_-	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]	NA|127aa|up_6|CP029043.1_4910089_4910470_+	NA	NA|252aa|up_5|CP029043.1_4910626_4911382_+	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	NA|90aa|up_4|CP029043.1_4911419_4911689_-	NA	NA|76aa|up_3|CP029043.1_4911916_4912144_-	pfam11305, DUF3107, Protein of unknown function (DUF3107)	NA|214aa|up_2|CP029043.1_4912300_4912942_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|75aa|up_1|CP029043.1_4913179_4913404_-	NA	NA|458aa|up_0|CP029043.1_4915142_4916516_+	pfam11350, DUF3152, Protein of unknown function (DUF3152)	NA|331aa|down_0|CP029043.1_4920521_4921514_+	pfam01370, Epimerase, NAD dependent epimerase/dehydratase family	NA|278aa|down_1|CP029043.1_4921501_4922335_+	pfam12138, Spherulin4, Spherulation-specific family 4	NA|393aa|down_2|CP029043.1_4922398_4923577_+	PRK07878, PRK07878, molybdopterin biosynthesis-like protein MoeZ; Validated	NA|516aa|down_3|CP029043.1_4923681_4925229_-	pfam08386, Abhydrolase_4, TAP-like protein	NA|516aa|down_4|CP029043.1_4925362_4926910_-	pfam08386, Abhydrolase_4, TAP-like protein	NA|929aa|down_5|CP029043.1_4927031_4929818_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|165aa|down_6|CP029043.1_4929896_4930391_+	COG3695, COG3695, Predicted methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]	NA|1118aa|down_7|CP029043.1_4930702_4934056_+	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]	NA|1230aa|down_8|CP029043.1_4934077_4937767_+	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]	NA|468aa|down_9|CP029043.1_4937777_4939181_+	cd05680, M20_dipept_like, uncharacterized M20 dipeptidase
