assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	1	145784-145875	1	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	CCACCTTTTTTACCTGCTTCAGATGC	26	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA|73aa|up_9|CP025753.1_134956_135175_+,NA|44aa|down_3|CP025753.1_148572_148704_-	NA|73aa|up_9|CP025753.1_134956_135175_+	NA	NA|1321aa|up_8|CP025753.1_135298_139261_+	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed	NA|213aa|up_7|CP025753.1_139300_139939_-	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional	NA|364aa|up_6|CP025753.1_140226_141318_+	TIGR03612, RutA, pyrimidine utilization protein A	NA|232aa|up_5|CP025753.1_141314_142010_+	TIGR03614, RutB, pyrimidine utilization protein B	NA|129aa|up_4|CP025753.1_142021_142408_+	TIGR03610, RutC, pyrimidine utilization protein C	NA|267aa|up_3|CP025753.1_142415_143216_+	TIGR03611, RutD, pyrimidine utilization protein D	NA|197aa|up_2|CP025753.1_143225_143816_+	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|165aa|up_1|CP025753.1_143826_144321_+	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F	NA|443aa|up_0|CP025753.1_144341_145670_+	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|199aa|down_0|CP025753.1_146298_146895_+	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|76aa|down_1|CP025753.1_146915_147143_+	PRK10174, PRK10174, hypothetical protein; Provisional	NA|414aa|down_2|CP025753.1_147180_148422_-	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional	NA|44aa|down_3|CP025753.1_148572_148704_-	NA	NA|420aa|down_4|CP025753.1_148713_149973_-	PRK09784, PRK09784, YccE family protein	NA|307aa|down_5|CP025753.1_150232_151153_+	PRK10266, PRK10266, curved DNA-binding protein	NA|102aa|down_6|CP025753.1_151152_151458_+	PRK10265, PRK10265, chaperone modulator CbpM	NA|200aa|down_7|CP025753.1_151550_152150_-	PRK04976, torD, chaperone protein TorD; Validated	NA|849aa|down_8|CP025753.1_152146_154693_-	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA	NA|391aa|down_9|CP025753.1_154692_155865_-	PRK15032, PRK15032, pentaheme c-type cytochrome TorC
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	2	408848-408992	2	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	52	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA|39aa|down_3|CP025753.1_414106_414223_-	NA|330aa|up_9|CP025753.1_396746_397736_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|303aa|up_8|CP025753.1_398132_399041_+	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related	NA|674aa|up_7|CP025753.1_399232_401254_-	PRK05298, PRK05298, excinuclease ABC subunit UvrB	NA|226aa|up_6|CP025753.1_401832_402510_-	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD	NA|252aa|up_5|CP025753.1_402502_403258_-	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional	NA|385aa|up_4|CP025753.1_403244_404399_-	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed	NA|347aa|up_3|CP025753.1_404395_405436_-	PRK15108, PRK15108, biotin synthase; Provisional	NA|411aa|up_2|CP025753.1_405579_406812_+	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated	NA|159aa|up_1|CP025753.1_406870_407347_+	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional	NA|428aa|up_0|CP025753.1_407498_408782_+	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase	NA|754aa|down_0|CP025753.1_409015_411277_-	PRK11413, PRK11413, putative hydratase; Provisional	NA|478aa|down_1|CP025753.1_411459_412893_-	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region	NA|351aa|down_2|CP025753.1_412968_414021_-	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase	NA|39aa|down_3|CP025753.1_414106_414223_-	NA	NA|318aa|down_4|CP025753.1_414204_415158_+	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|332aa|down_5|CP025753.1_415198_416194_-	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional	NA|307aa|down_6|CP025753.1_416246_417167_+	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional	NA|353aa|down_7|CP025753.1_417167_418226_-	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC	NA|230aa|down_8|CP025753.1_418228_418918_-	PRK09421, modB, molybdate ABC transporter permease subunit	NA|258aa|down_9|CP025753.1_418917_419691_-	PRK10677, modA, molybdate transporter periplasmic protein; Provisional
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	3	908923-909076	3	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCG	53	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA|150aa|down_9|CP025753.1_918653_919103_-	NA|415aa|up_9|CP025753.1_900301_901546_-	PRK05077, frsA, esterase FrsA	NA|153aa|up_8|CP025753.1_901637_902096_-	PRK09177, PRK09177, xanthine-guanine phosphoribosyltransferase; Validated	NA|486aa|up_7|CP025753.1_902356_903814_+	PRK15026, PRK15026, aminoacyl-histidine dipeptidase; Provisional	NA|47aa|up_6|CP025753.1_903870_904011_-	PRK08179, prfH, peptide chain release factor-like protein; Reviewed	NA|66aa|up_5|CP025753.1_904004_904202_-	PRK08179, prfH, peptide chain release factor-like protein; Reviewed	NA|85aa|up_4|CP025753.1_904170_904425_-	PRK09588, PRK09588, hypothetical protein; Reviewed	NA|151aa|up_3|CP025753.1_904743_905196_-	PRK09831, PRK09831, GNAT family N-acetyltransferase	NA|352aa|up_2|CP025753.1_905192_906248_-	PRK02406, PRK02406, DNA polymerase IV; Validated	NA|257aa|up_1|CP025753.1_906318_907089_-	PRK06778, PRK06778, hypothetical protein; Validated	NA|580aa|up_0|CP025753.1_907048_908788_+	COG1298, FlhA, Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]	NA|166aa|down_0|CP025753.1_909105_909603_-	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|250aa|down_1|CP025753.1_909778_910528_-	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]	NA|247aa|down_2|CP025753.1_910828_911569_+	COG3034, COG3034, Uncharacterized protein conserved in bacteria [Function unknown]	NA|256aa|down_3|CP025753.1_911539_912307_-	pfam13230, GATase_4, Glutamine amidotransferases class-II	NA|193aa|down_4|CP025753.1_912512_913091_-	PRK00414, gmhA, D-sedoheptulose 7-phosphate isomerase	NA|815aa|down_5|CP025753.1_913330_915775_+	PRK09463, fadE, acyl-CoA dehydrogenase; Reviewed	NA|150aa|down_6|CP025753.1_915817_916267_-	PRK09993, PRK09993, C-lysozyme inhibitor; Provisional	NA|257aa|down_7|CP025753.1_916444_917215_+	PRK10438, PRK10438, C-N hydrolase family amidase; Provisional	NA|348aa|down_8|CP025753.1_917256_918300_-	COG5433, COG5433, Transposase [DNA replication, recombination, and repair]	NA|150aa|down_9|CP025753.1_918653_919103_-	NA
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	4	1118792-1118907	4	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	AACGCCTGATGCGACGCTGACGCGTCTTATC	31	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA	NA|393aa|up_9|CP025753.1_1106807_1107986_-	TIGR00899, Sugar_efflux_transporter_A, sugar efflux transporter	NA|44aa|up_8|CP025753.1_1108087_1108219_-	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT	NA|552aa|up_7|CP025753.1_1108307_1109963_+	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR	NA|328aa|up_6|CP025753.1_1110126_1111110_+	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional	NA|537aa|up_5|CP025753.1_1111085_1112696_+	PRK09433, thiP, thiamine transporter membrane protein; Reviewed	NA|233aa|up_4|CP025753.1_1112679_1113378_+	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ	NA|255aa|up_3|CP025753.1_1113491_1114256_-	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|310aa|up_2|CP025753.1_1114341_1115271_-	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC	NA|567aa|up_1|CP025753.1_1115558_1117259_+	PRK04123, PRK04123, ribulokinase; Provisional	NA|501aa|up_0|CP025753.1_1117269_1118772_+	PRK02929, PRK02929, L-arabinose isomerase; Provisional	NA|232aa|down_0|CP025753.1_1118971_1119667_+	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD	NA|784aa|down_1|CP025753.1_1119741_1122093_+	PRK05762, PRK05762, DNA polymerase II; Reviewed	NA|920aa|down_2|CP025753.1_1122404_1125164_+	PRK04914, PRK04914, RNA polymerase-associated protein RapA	NA|220aa|down_3|CP025753.1_1125175_1125835_+	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA|272aa|down_4|CP025753.1_1125951_1126767_-	PRK09430, djlA, co-chaperone DjlA	NA|785aa|down_5|CP025753.1_1127021_1129376_+	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional	NA|429aa|down_6|CP025753.1_1129428_1130715_+	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional	NA|330aa|down_7|CP025753.1_1130714_1131704_+	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed	NA|274aa|down_8|CP025753.1_1131700_1132522_+	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA	NA|126aa|down_9|CP025753.1_1132524_1132902_+	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	5	1141820-1141952	1	PILER-CR	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	ATCACCAATATTGAAAA	17	0	0	NA	NA	NA	2	2	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA|73aa|down_7|CP025753.1_1149868_1150087_+	NA|126aa|up_9|CP025753.1_1132524_1132902_+	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed	NA|281aa|up_8|CP025753.1_1132908_1133751_+	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical)	NA|197aa|up_7|CP025753.1_1133828_1134419_-	PRK10769, folA, type 3 dihydrofolate reductase	NA|621aa|up_6|CP025753.1_1134499_1136362_-	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional	NA|177aa|up_5|CP025753.1_1136354_1136885_-	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF	NA|444aa|up_4|CP025753.1_1136992_1138324_-	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily	NA|96aa|up_3|CP025753.1_1138381_1138669_-	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional	NA|429aa|up_2|CP025753.1_1138665_1139952_-	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional	NA|314aa|up_1|CP025753.1_1140002_1140944_-	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein	NA|257aa|up_0|CP025753.1_1140958_1141729_-	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed	NA|505aa|down_0|CP025753.1_1142202_1143717_+	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter	NA|381aa|down_1|CP025753.1_1143747_1144890_+	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated	NA|406aa|down_2|CP025753.1_1145018_1146236_+	PRK03525, PRK03525, L-carnitine CoA-transferase	NA|518aa|down_3|CP025753.1_1146309_1147863_+	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated	NA|298aa|down_4|CP025753.1_1147863_1148757_+	PRK03580, PRK03580, crotonobetainyl-CoA hydratase	NA|197aa|down_5|CP025753.1_1148762_1149353_+	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional	NA|132aa|down_6|CP025753.1_1149438_1149834_-	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF	NA|73aa|down_7|CP025753.1_1149868_1150087_+	NA	NA|1074aa|down_8|CP025753.1_1150094_1153316_-	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|348aa|down_9|CP025753.1_1153333_1154377_-	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	6	2581042-2581181	5	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA	49	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA	NA|336aa|up_9|CP025753.1_2573507_2574515_-	PRK10508, PRK10508, luciferase-like monooxygenase	NA|293aa|up_8|CP025753.1_2574720_2575599_-	PRK15447, PRK15447, putative protease; Provisional	NA|332aa|up_7|CP025753.1_2575607_2576603_-	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]	NA|175aa|up_6|CP025753.1_2576811_2577336_+	COG3154, COG3154, Putative lipid carrier protein [Lipid metabolism]	NA|168aa|up_5|CP025753.1_2577329_2577833_+	COG3153, COG3153, Predicted acetyltransferase [General function prediction only]	NA|94aa|up_4|CP025753.1_2577819_2578101_-	PRK00329, PRK00329, GIY-YIG nuclease superfamily protein; Validated	NA|148aa|up_3|CP025753.1_2578172_2578616_+	PRK03467, PRK03467, hypothetical protein; Provisional	NA|173aa|up_2|CP025753.1_2578595_2579114_-	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus	NA|212aa|up_1|CP025753.1_2579241_2579877_+	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs	NA|347aa|up_0|CP025753.1_2579949_2580990_+	COG0701, COG0701, Predicted permeases [General function prediction only]	NA|192aa|down_0|CP025753.1_2581194_2581770_-	PRK11023, PRK11023, divisome-associated lipoprotein YraP	NA|197aa|down_1|CP025753.1_2581779_2582370_-	PRK10886, PRK10886, DnaA initiator-associating protein DiaA; Provisional	NA|132aa|down_2|CP025753.1_2582389_2582785_-	TIGR00252, UPF0102_protein_HI_1656, TIGR00252 family protein	NA|679aa|down_3|CP025753.1_2582742_2584779_-	COG3107, LppC, Putative lipoprotein [General function prediction only]	NA|287aa|down_4|CP025753.1_2584843_2585704_+	PRK14994, PRK14994, SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional	NA|364aa|down_5|CP025753.1_2585746_2586838_-	pfam00419, Fimbrial, Fimbrial protein	NA|425aa|down_6|CP025753.1_2586848_2588123_-	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]	NA|302aa|down_7|CP025753.1_2588107_2589013_-	PRK09409, PRK09409, IS2 transposase TnpB; Reviewed	NA|82aa|down_8|CP025753.1_2588970_2589216_-	PRK09413, PRK09413, IS2 repressor TnpA; Reviewed	NA|430aa|down_9|CP025753.1_2589411_2590701_-	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	7	2626396-2626513	6	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	40	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA|56aa|down_0|CP025753.1_2626586_2626754_-	NA|115aa|up_9|CP025753.1_2614117_2614462_-	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional	NA|313aa|up_8|CP025753.1_2614650_2615589_+	PRK10341, PRK10341, transcriptional regulator TdcA	NA|330aa|up_7|CP025753.1_2615687_2616677_+	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA|444aa|up_6|CP025753.1_2616698_2618030_+	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional	NA|403aa|up_5|CP025753.1_2618055_2619264_+	PRK12379, PRK12379, propionate kinase	NA|765aa|up_4|CP025753.1_2619297_2621592_+	cd01678, PFL1, Pyruvate formate lyase 1	NA|130aa|up_3|CP025753.1_2621605_2621995_+	PRK11401, PRK11401, enamine/imine deaminase	NA|455aa|up_2|CP025753.1_2622066_2623431_+	PRK15040, PRK15040, L-serine ammonia-lyase	NA|444aa|up_1|CP025753.1_2623705_2625037_+	TIGR00814, membrane_transport_protein_YhjV, serine transporter	NA|437aa|up_0|CP025753.1_2625064_2626375_+	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|56aa|down_0|CP025753.1_2626586_2626754_-	NA	NA|217aa|down_1|CP025753.1_2626773_2627424_-	COG1741, COG1741, Pirin-related protein [General function prediction only]	NA|299aa|down_2|CP025753.1_2627579_2628476_+	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold	NA|119aa|down_3|CP025753.1_2628526_2628883_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|122aa|down_4|CP025753.1_2629124_2629490_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|329aa|down_5|CP025753.1_2629782_2630769_-	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]	NA|161aa|down_6|CP025753.1_2630838_2631321_-	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|100aa|down_7|CP025753.1_2631416_2631716_-	pfam13997, YqjK, YqjK-like protein	NA|135aa|down_8|CP025753.1_2631705_2632110_-	COG5393, COG5393, Predicted membrane protein [Function unknown]	NA|102aa|down_9|CP025753.1_2632112_2632418_-	COG4575, ElaB, Uncharacterized conserved protein [Function unknown]
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	8	3055500-3055955	2,7,1	PILER-CR,CRISPRCasFinder,CRT	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	GAGTTCCCCGCGCCAGCGGGGATAAACCG,GAGTTCCCCGCGCCAGCGGGGATAAACCG,GAGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	0	0	NA	NA	I-E:I-E:I-E	7,7,7	7	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA|47aa|up_1|CP025753.1_3054209_3054350_-,NA	NA|434aa|up_9|CP025753.1_3044906_3046208_+	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	NA|745aa|up_8|CP025753.1_3046255_3048490_+	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|83aa|up_7|CP025753.1_3048567_3048816_+	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|112aa|up_6|CP025753.1_3048815_3049151_+	PRK09907, PRK09907, endoribonuclease MazF	NA|264aa|up_5|CP025753.1_3049221_3050013_+	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|546aa|up_4|CP025753.1_3050240_3051878_+	PRK05380, pyrG, CTP synthetase; Validated	NA|433aa|up_3|CP025753.1_3051965_3053264_+	PRK00077, eno, enolase; Provisional	NA|291aa|up_2|CP025753.1_3053323_3054196_-	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|47aa|up_1|CP025753.1_3054209_3054350_-	NA	NA|224aa|up_0|CP025753.1_3054488_3055160_+	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|493aa|down_0|CP025753.1_3056592_3058071_-	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|426aa|down_1|CP025753.1_3058097_3059375_-	cd06174, MFS, Major Facilitator Superfamily	NA|262aa|down_2|CP025753.1_3059693_3060479_+	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|485aa|down_3|CP025753.1_3060548_3062003_+	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|446aa|down_4|CP025753.1_3062096_3063434_+	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|260aa|down_5|CP025753.1_3063411_3064191_+	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|287aa|down_6|CP025753.1_3064187_3065048_+	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|192aa|down_7|CP025753.1_3065195_3065771_-	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|87aa|down_8|CP025753.1_3065787_3066048_-	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|424aa|down_9|CP025753.1_3066038_3067310_-	PRK10015, PRK10015, oxidoreductase; Provisional
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	9	3083002-3083885	8,3,2	CRISPRCasFinder,PILER-CR,CRT	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Type I-E	TGTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG	30,29,29	0	0	NA	NA	I-E:I-E:I-E	13,13,14	14	TypeI-E	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA,NA	NA|51aa|up_9|CP025753.1_3072652_3072805_+	pfam01848, HOK_GEF, Hok/gef family	NA|371aa|up_8|CP025753.1_3072997_3074110_-	pfam01609, DDE_Tnp_1, Transposase DDE domain	cas3|900aa|up_7|CP025753.1_3074347_3077047_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas8e|521aa|up_6|CP025753.1_3077144_3078707_+	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1	cse2gr11|179aa|up_5|CP025753.1_3078703_3079240_+	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2	cas7|352aa|up_4|CP025753.1_3079251_3080307_+	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cas5|249aa|up_3|CP025753.1_3080317_3081064_+	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas6e|217aa|up_2|CP025753.1_3081045_3081696_+	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas1|308aa|up_1|CP025753.1_3081692_3082616_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|96aa|up_0|CP025753.1_3082618_3082906_+	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	NA|346aa|down_0|CP025753.1_3083905_3084943_-	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	NA|303aa|down_1|CP025753.1_3085194_3086103_+	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|476aa|down_2|CP025753.1_3086104_3087532_+	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|202aa|down_3|CP025753.1_3087531_3088137_+	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|108aa|down_4|CP025753.1_3088186_3088510_+	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|104aa|down_5|CP025753.1_3088703_3089015_+	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|237aa|down_6|CP025753.1_3089033_3089744_+	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|160aa|down_7|CP025753.1_3089743_3090223_+	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|350aa|down_8|CP025753.1_3090219_3091269_+	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|254aa|down_9|CP025753.1_3091249_3092011_+	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional
GCA_002893905.2_ASM289390v2	CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	10	3610644-3610785	9	CRISPRCasFinder	no		cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	Orphan	CGCGTCTTATCAGGCCTACAAATCCGAGCCGTAGGCCGGATAAGGCGTTCACGC	54	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	NA|66aa|up_8|CP025753.1_3603618_3603816_-,NA|357aa|up_5|CP025753.1_3606524_3607595_-,NA|44aa|up_4|CP025753.1_3607773_3607905_-,NA	NA|543aa|up_9|CP025753.1_3601965_3603594_-	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA|66aa|up_8|CP025753.1_3603618_3603816_-	NA	NA|453aa|up_7|CP025753.1_3603866_3605225_+	PRK11273, glpT, glycerol-3-phosphate transporter	NA|359aa|up_6|CP025753.1_3605229_3606306_+	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional	NA|357aa|up_5|CP025753.1_3606524_3607595_-	NA	NA|44aa|up_4|CP025753.1_3607773_3607905_-	NA	NA|69aa|up_3|CP025753.1_3608060_3608267_-	PRK09729, PRK09729, hypothetical protein; Provisional	NA|217aa|up_2|CP025753.1_3608481_3609132_+	PRK09902, PRK09902, lipopolysaccharide kinase InaA	NA|85aa|up_1|CP025753.1_3609185_3609440_-	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein	NA|390aa|up_0|CP025753.1_3609439_3610609_-	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed	NA|762aa|down_0|CP025753.1_3610804_3613090_-	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha	NA|1235aa|down_1|CP025753.1_3613833_3617538_+	PRK09752, PRK09752, AIDA-I family autotransporter YfaL	NA|241aa|down_2|CP025753.1_3617665_3618388_-	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	NA|876aa|down_3|CP025753.1_3618534_3621162_+	PRK05560, PRK05560, DNA gyrase subunit A; Validated	NA|563aa|down_4|CP025753.1_3621310_3622999_+	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown]	NA|208aa|down_5|CP025753.1_3622995_3623619_+	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown]	NA|1505aa|down_6|CP025753.1_3623642_3628157_+	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only]	NA|550aa|down_7|CP025753.1_3628157_3629807_+	COG5445, COG5445, Predicted secreted protein [Function unknown]	NA|259aa|down_8|CP025753.1_3629811_3630588_+	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown]	NA|395aa|down_9|CP025753.1_3630661_3631846_-	PRK05790, PRK05790, putative acyltransferase; Provisional
